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Conserved domains on  [gi|1046754173|ref|NP_001316643|]
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protein FAM163A [Homo sapiens]

Protein Classification

FAM163 domain-containing protein( domain architecture ID 10633389)

FAM163 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FAM163 pfam15069
FAM163 family; This protein family is alternatively named Neuroblastoma-derived secretory ...
1-167 5.49e-79

FAM163 family; This protein family is alternatively named Neuroblastoma-derived secretory proteins. Highly expressed in neuroblastoma compared to other tissues, suggesting that it may be used as a marker for metastasis in bone marrow.


:

Pssm-ID: 464484  Cd Length: 164  Bit Score: 231.50  E-value: 5.49e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046754173   1 MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKSGTEVADEEEEREHDLPTHprgpTCNACSSQALDGRGSLAPLT 80
Cdd:pfam15069   1 MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEEEEEEPDFAVIPPL----ACNACSSNGVDGPAVTANGP 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046754173  81 SEPCSQP----CGVAASHCTTCSPYSSPFYIRTADMVPNggGGERLSFAPTYYKEGGPPsLKLAAPQSYPVTWPGSGREA 156
Cdd:pfam15069  77 SEPSSPPfpkkCGGSRSYCPSCSPYSSPFYLRTPDEVRN--GGERISYMPTHYEDLGLP-VDLANLQGLNLSRSSTMREA 153
                         170
                  ....*....|.
gi 1046754173 157 FTNPRAISTDV 167
Cdd:pfam15069 154 FTNSRAISTDV 164
 
Name Accession Description Interval E-value
FAM163 pfam15069
FAM163 family; This protein family is alternatively named Neuroblastoma-derived secretory ...
1-167 5.49e-79

FAM163 family; This protein family is alternatively named Neuroblastoma-derived secretory proteins. Highly expressed in neuroblastoma compared to other tissues, suggesting that it may be used as a marker for metastasis in bone marrow.


Pssm-ID: 464484  Cd Length: 164  Bit Score: 231.50  E-value: 5.49e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046754173   1 MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKSGTEVADEEEEREHDLPTHprgpTCNACSSQALDGRGSLAPLT 80
Cdd:pfam15069   1 MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEEEEEEPDFAVIPPL----ACNACSSNGVDGPAVTANGP 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046754173  81 SEPCSQP----CGVAASHCTTCSPYSSPFYIRTADMVPNggGGERLSFAPTYYKEGGPPsLKLAAPQSYPVTWPGSGREA 156
Cdd:pfam15069  77 SEPSSPPfpkkCGGSRSYCPSCSPYSSPFYLRTPDEVRN--GGERISYMPTHYEDLGLP-VDLANLQGLNLSRSSTMREA 153
                         170
                  ....*....|.
gi 1046754173 157 FTNPRAISTDV 167
Cdd:pfam15069 154 FTNSRAISTDV 164
 
Name Accession Description Interval E-value
FAM163 pfam15069
FAM163 family; This protein family is alternatively named Neuroblastoma-derived secretory ...
1-167 5.49e-79

FAM163 family; This protein family is alternatively named Neuroblastoma-derived secretory proteins. Highly expressed in neuroblastoma compared to other tissues, suggesting that it may be used as a marker for metastasis in bone marrow.


Pssm-ID: 464484  Cd Length: 164  Bit Score: 231.50  E-value: 5.49e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046754173   1 MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKSGTEVADEEEEREHDLPTHprgpTCNACSSQALDGRGSLAPLT 80
Cdd:pfam15069   1 MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEEEEEEPDFAVIPPL----ACNACSSNGVDGPAVTANGP 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046754173  81 SEPCSQP----CGVAASHCTTCSPYSSPFYIRTADMVPNggGGERLSFAPTYYKEGGPPsLKLAAPQSYPVTWPGSGREA 156
Cdd:pfam15069  77 SEPSSPPfpkkCGGSRSYCPSCSPYSSPFYLRTPDEVRN--GGERISYMPTHYEDLGLP-VDLANLQGLNLSRSSTMREA 153
                         170
                  ....*....|.
gi 1046754173 157 FTNPRAISTDV 167
Cdd:pfam15069 154 FTNSRAISTDV 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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