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Conserved domains on  [gi|1033837602|ref|NP_001314965|]
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uncharacterized protein KIAA0232 homolog [Danio rerio]

Protein Classification

DUF4603 domain-containing protein( domain architecture ID 10634086)

DUF4603 domain-containing protein similar to Homo sapiens protein KIAA0232

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 24-1315 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


:

Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2292.05  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602   24 GPVSSSEMSSLQSLGPVQSWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIFLGWEKGAAKKWGKSKRKGgT 103
Cdd:pfam15376    1 GPLPASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIFLGWEKGAGKKWGKSKKKG-T 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  104 DLSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDIQNKQKEkEKHGIKKSDISQSPEPDESLSSKDQVEMYYEAF 183
Cdd:pfam15376   80 DLSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQKE-EKKINKKSEGSQSPERDESPSSKDQVEMYYEAF 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  184 PPLSEKPVCLQEIMTVWNTAKACTYSSSSSSAVPQTSTDTSSPKDCTSEGEAFKDRTVDAPSstsTTSEKAQQRRTKREK 263
Cdd:pfam15376  159 PPLSEKPVCLQEIMTVWNKAKACSYSSSSSSAAPQTSTDTSSPKDCNSEGEATKERNSEAPA---TTSERTQQRRSKKEK 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  264 ENRFHGsatGMPDDQVAPHSKRQARHRSEGRFRPRSWSSGSSEAGSSSSGNQGDQAPSCKSVRIRHKSREvSGRNKKGRS 343
Cdd:pfam15376  236 ENRFHN---GAAEEKSAVHSKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSRE-AVRNKKGRN 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  344 GggQVKLALKVIDKEERKNARGNMSTTGGPPKQQQhYMKKGKRPLREIRKDANLVEAQESGGEA-SKKEYMEEPLWYTEP 422
Cdd:pfam15376  312 G--QVKLALKVIDKEERRNAGGSSSSASGGSIKQQ-LCKKGKRPLKEIRKDPGWVEGKESGGEArNKKEYMEEPLWYTEP 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  423 IAEYFVPLSR-SKLETKYRSKEDSSNDLAMSIDVDCLSERIQGICIANSCFQRAYLAAGTFVDGHFIEMPGEGDEeASEL 501
Cdd:pfam15376  389 ITEYFVPLSRkSKLETKYRSKEDSPDGFALSIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNE-AADL 467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  502 NGIPSCPPPEDGQDLDDEHLSEFTHFYEVDLYQSILDPSASDAVQESRILSMIRQKSVERKHFEAG-CVVLDGLELQGES 580
Cdd:pfam15376  468 NGTSSCPQPEDNKDLDDEHLSEFTHFYEVDIYQSILDPSASDSVQESRILNMIRQKSKEQRDFEAEcCIVLDGLELQGES 547

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  581 AIRVDSLGASEAEVSITQDMENIAQVWECCSSSSLEDLEGESCPGDSPGRLSPVLDSVPFNFSKLSGAYVGsRLQEASGS 660
Cdd:pfam15376  548 AIRADSTSASGAEGFLMQDLENIAQVWECCSSSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEE-LFSEANEG 626

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  661 SSAPNPYFSLFEVQYDSPTFSFPCDSLTGGQENVDSSSCLDPQGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSE 740
Cdd:pfam15376  627 SGLNSSCFSLFEVQYDSSTFPFPRDSLTLGHENTDSSSCLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSE 706

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  741 ETRSDSEQVSAPADESAQFGNEEVSCIslIPPLC---LEEELLDFFQENSSHqQEETSVSAESNQPFNKKSKLESVCGIA 817
Cdd:pfam15376  707 ETRSDNEQFNAQAEESAQFGNEEINCV--IPPLSstyLEEELLDFLQEESCH-QEEVSVSTASNQTFKKKSKLESVCGIA 783

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  818 LEQDESKLY-NAVVFSDVPNQQSDEYTSGIIKDIWMAIGDRDCVLTLGVKNTGEHLFSEDSTSYQCSCLDKDAKGEIIQ- 895
Cdd:pfam15376  784 LEQDESKQYeSTGVFSDNSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYCCCCLDVEAKGEPLQe 863

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  896 -KKAVQCSEYHLWDGQK---ENDGLPKNKLTKMNDGDYTAPAKPWNCNSQESTSFILGGVYGELKTLSGDREWAMIPPGD 971
Cdd:pfam15376  864 qKKAVQRSEYHLWEGQKenlEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSD 943

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  972 ACGSLLQCAAatsSDMVTIAGADVFMNTSSCFAPGHKPLWRPIVSLGQNEQATKGTGEGLNKGFSVVFHEDLLGSCGGFR 1051
Cdd:pfam15376  944 SRGSLLQCAA---SDVVTIAGTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAIKGGGDGLNKGFSFIFHEDLLGSCGNFR 1020

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602 1052 GEESGLDYPFSSFDLNNPFSQVLHVECSFEPEDMASFSPGFKPKSILCSD--KEPFCPWLYGINRTQYRAIRISPRTHFR 1129
Cdd:pfam15376 1021 GEEPGLEYPFSSFDLNNPFSQVLHVECSFEPEDIASFSPGFKPKSILCSDseNEVFHPRIYGINRTQYRAIRISPRTHFR 1100

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602 1130 PISASELSPGGCSESDVESEKEEASIPV-GQADLFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQ 1208
Cdd:pfam15376 1101 PISASELSPGGGSESEAESEKEEASIPVlSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQ 1180

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602 1209 TSLDSQEGGSTLLPITEQEICVHCEVAADSVPCSHVQSSVLL------QEETSGETEPCNCVATGQIPKSGKSLDVAQDM 1282
Cdd:pfam15376 1181 TSLDSQEGSGGLLPIAEQEICLDCSIAASLESISTEGSKTNCkigepqKEESSGEKEFCSCKAACQIPKYGKAYDFAGDL 1260

                         1290      1300      1310
                   ....*....|....*....|....*....|...
gi 1033837602 1283 HEFPLLNFGEQCLTNMQQEECWWQSSLCSPLFP 1315
Cdd:pfam15376 1261 PEFPLLNIDLQGGTGSQQEECWWQKALCSPLFP 1293
 
Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 24-1315 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2292.05  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602   24 GPVSSSEMSSLQSLGPVQSWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIFLGWEKGAAKKWGKSKRKGgT 103
Cdd:pfam15376    1 GPLPASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIFLGWEKGAGKKWGKSKKKG-T 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  104 DLSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDIQNKQKEkEKHGIKKSDISQSPEPDESLSSKDQVEMYYEAF 183
Cdd:pfam15376   80 DLSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQKE-EKKINKKSEGSQSPERDESPSSKDQVEMYYEAF 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  184 PPLSEKPVCLQEIMTVWNTAKACTYSSSSSSAVPQTSTDTSSPKDCTSEGEAFKDRTVDAPSstsTTSEKAQQRRTKREK 263
Cdd:pfam15376  159 PPLSEKPVCLQEIMTVWNKAKACSYSSSSSSAAPQTSTDTSSPKDCNSEGEATKERNSEAPA---TTSERTQQRRSKKEK 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  264 ENRFHGsatGMPDDQVAPHSKRQARHRSEGRFRPRSWSSGSSEAGSSSSGNQGDQAPSCKSVRIRHKSREvSGRNKKGRS 343
Cdd:pfam15376  236 ENRFHN---GAAEEKSAVHSKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSRE-AVRNKKGRN 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  344 GggQVKLALKVIDKEERKNARGNMSTTGGPPKQQQhYMKKGKRPLREIRKDANLVEAQESGGEA-SKKEYMEEPLWYTEP 422
Cdd:pfam15376  312 G--QVKLALKVIDKEERRNAGGSSSSASGGSIKQQ-LCKKGKRPLKEIRKDPGWVEGKESGGEArNKKEYMEEPLWYTEP 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  423 IAEYFVPLSR-SKLETKYRSKEDSSNDLAMSIDVDCLSERIQGICIANSCFQRAYLAAGTFVDGHFIEMPGEGDEeASEL 501
Cdd:pfam15376  389 ITEYFVPLSRkSKLETKYRSKEDSPDGFALSIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNE-AADL 467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  502 NGIPSCPPPEDGQDLDDEHLSEFTHFYEVDLYQSILDPSASDAVQESRILSMIRQKSVERKHFEAG-CVVLDGLELQGES 580
Cdd:pfam15376  468 NGTSSCPQPEDNKDLDDEHLSEFTHFYEVDIYQSILDPSASDSVQESRILNMIRQKSKEQRDFEAEcCIVLDGLELQGES 547

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  581 AIRVDSLGASEAEVSITQDMENIAQVWECCSSSSLEDLEGESCPGDSPGRLSPVLDSVPFNFSKLSGAYVGsRLQEASGS 660
Cdd:pfam15376  548 AIRADSTSASGAEGFLMQDLENIAQVWECCSSSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEE-LFSEANEG 626

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  661 SSAPNPYFSLFEVQYDSPTFSFPCDSLTGGQENVDSSSCLDPQGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSE 740
Cdd:pfam15376  627 SGLNSSCFSLFEVQYDSSTFPFPRDSLTLGHENTDSSSCLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSE 706

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  741 ETRSDSEQVSAPADESAQFGNEEVSCIslIPPLC---LEEELLDFFQENSSHqQEETSVSAESNQPFNKKSKLESVCGIA 817
Cdd:pfam15376  707 ETRSDNEQFNAQAEESAQFGNEEINCV--IPPLSstyLEEELLDFLQEESCH-QEEVSVSTASNQTFKKKSKLESVCGIA 783

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  818 LEQDESKLY-NAVVFSDVPNQQSDEYTSGIIKDIWMAIGDRDCVLTLGVKNTGEHLFSEDSTSYQCSCLDKDAKGEIIQ- 895
Cdd:pfam15376  784 LEQDESKQYeSTGVFSDNSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYCCCCLDVEAKGEPLQe 863

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  896 -KKAVQCSEYHLWDGQK---ENDGLPKNKLTKMNDGDYTAPAKPWNCNSQESTSFILGGVYGELKTLSGDREWAMIPPGD 971
Cdd:pfam15376  864 qKKAVQRSEYHLWEGQKenlEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSD 943

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  972 ACGSLLQCAAatsSDMVTIAGADVFMNTSSCFAPGHKPLWRPIVSLGQNEQATKGTGEGLNKGFSVVFHEDLLGSCGGFR 1051
Cdd:pfam15376  944 SRGSLLQCAA---SDVVTIAGTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAIKGGGDGLNKGFSFIFHEDLLGSCGNFR 1020

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602 1052 GEESGLDYPFSSFDLNNPFSQVLHVECSFEPEDMASFSPGFKPKSILCSD--KEPFCPWLYGINRTQYRAIRISPRTHFR 1129
Cdd:pfam15376 1021 GEEPGLEYPFSSFDLNNPFSQVLHVECSFEPEDIASFSPGFKPKSILCSDseNEVFHPRIYGINRTQYRAIRISPRTHFR 1100

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602 1130 PISASELSPGGCSESDVESEKEEASIPV-GQADLFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQ 1208
Cdd:pfam15376 1101 PISASELSPGGGSESEAESEKEEASIPVlSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQ 1180

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602 1209 TSLDSQEGGSTLLPITEQEICVHCEVAADSVPCSHVQSSVLL------QEETSGETEPCNCVATGQIPKSGKSLDVAQDM 1282
Cdd:pfam15376 1181 TSLDSQEGSGGLLPIAEQEICLDCSIAASLESISTEGSKTNCkigepqKEESSGEKEFCSCKAACQIPKYGKAYDFAGDL 1260

                         1290      1300      1310
                   ....*....|....*....|....*....|...
gi 1033837602 1283 HEFPLLNFGEQCLTNMQQEECWWQSSLCSPLFP 1315
Cdd:pfam15376 1261 PEFPLLNIDLQGGTGSQQEECWWQKALCSPLFP 1293
 
Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 24-1315 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2292.05  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602   24 GPVSSSEMSSLQSLGPVQSWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIFLGWEKGAAKKWGKSKRKGgT 103
Cdd:pfam15376    1 GPLPASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIFLGWEKGAGKKWGKSKKKG-T 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  104 DLSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDIQNKQKEkEKHGIKKSDISQSPEPDESLSSKDQVEMYYEAF 183
Cdd:pfam15376   80 DLSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQKE-EKKINKKSEGSQSPERDESPSSKDQVEMYYEAF 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  184 PPLSEKPVCLQEIMTVWNTAKACTYSSSSSSAVPQTSTDTSSPKDCTSEGEAFKDRTVDAPSstsTTSEKAQQRRTKREK 263
Cdd:pfam15376  159 PPLSEKPVCLQEIMTVWNKAKACSYSSSSSSAAPQTSTDTSSPKDCNSEGEATKERNSEAPA---TTSERTQQRRSKKEK 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  264 ENRFHGsatGMPDDQVAPHSKRQARHRSEGRFRPRSWSSGSSEAGSSSSGNQGDQAPSCKSVRIRHKSREvSGRNKKGRS 343
Cdd:pfam15376  236 ENRFHN---GAAEEKSAVHSKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSRE-AVRNKKGRN 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  344 GggQVKLALKVIDKEERKNARGNMSTTGGPPKQQQhYMKKGKRPLREIRKDANLVEAQESGGEA-SKKEYMEEPLWYTEP 422
Cdd:pfam15376  312 G--QVKLALKVIDKEERRNAGGSSSSASGGSIKQQ-LCKKGKRPLKEIRKDPGWVEGKESGGEArNKKEYMEEPLWYTEP 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  423 IAEYFVPLSR-SKLETKYRSKEDSSNDLAMSIDVDCLSERIQGICIANSCFQRAYLAAGTFVDGHFIEMPGEGDEeASEL 501
Cdd:pfam15376  389 ITEYFVPLSRkSKLETKYRSKEDSPDGFALSIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNE-AADL 467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  502 NGIPSCPPPEDGQDLDDEHLSEFTHFYEVDLYQSILDPSASDAVQESRILSMIRQKSVERKHFEAG-CVVLDGLELQGES 580
Cdd:pfam15376  468 NGTSSCPQPEDNKDLDDEHLSEFTHFYEVDIYQSILDPSASDSVQESRILNMIRQKSKEQRDFEAEcCIVLDGLELQGES 547

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  581 AIRVDSLGASEAEVSITQDMENIAQVWECCSSSSLEDLEGESCPGDSPGRLSPVLDSVPFNFSKLSGAYVGsRLQEASGS 660
Cdd:pfam15376  548 AIRADSTSASGAEGFLMQDLENIAQVWECCSSSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEE-LFSEANEG 626

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  661 SSAPNPYFSLFEVQYDSPTFSFPCDSLTGGQENVDSSSCLDPQGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSE 740
Cdd:pfam15376  627 SGLNSSCFSLFEVQYDSSTFPFPRDSLTLGHENTDSSSCLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSE 706

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  741 ETRSDSEQVSAPADESAQFGNEEVSCIslIPPLC---LEEELLDFFQENSSHqQEETSVSAESNQPFNKKSKLESVCGIA 817
Cdd:pfam15376  707 ETRSDNEQFNAQAEESAQFGNEEINCV--IPPLSstyLEEELLDFLQEESCH-QEEVSVSTASNQTFKKKSKLESVCGIA 783

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  818 LEQDESKLY-NAVVFSDVPNQQSDEYTSGIIKDIWMAIGDRDCVLTLGVKNTGEHLFSEDSTSYQCSCLDKDAKGEIIQ- 895
Cdd:pfam15376  784 LEQDESKQYeSTGVFSDNSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYCCCCLDVEAKGEPLQe 863

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  896 -KKAVQCSEYHLWDGQK---ENDGLPKNKLTKMNDGDYTAPAKPWNCNSQESTSFILGGVYGELKTLSGDREWAMIPPGD 971
Cdd:pfam15376  864 qKKAVQRSEYHLWEGQKenlEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSD 943

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602  972 ACGSLLQCAAatsSDMVTIAGADVFMNTSSCFAPGHKPLWRPIVSLGQNEQATKGTGEGLNKGFSVVFHEDLLGSCGGFR 1051
Cdd:pfam15376  944 SRGSLLQCAA---SDVVTIAGTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAIKGGGDGLNKGFSFIFHEDLLGSCGNFR 1020

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602 1052 GEESGLDYPFSSFDLNNPFSQVLHVECSFEPEDMASFSPGFKPKSILCSD--KEPFCPWLYGINRTQYRAIRISPRTHFR 1129
Cdd:pfam15376 1021 GEEPGLEYPFSSFDLNNPFSQVLHVECSFEPEDIASFSPGFKPKSILCSDseNEVFHPRIYGINRTQYRAIRISPRTHFR 1100

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602 1130 PISASELSPGGCSESDVESEKEEASIPV-GQADLFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQ 1208
Cdd:pfam15376 1101 PISASELSPGGGSESEAESEKEEASIPVlSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQ 1180

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033837602 1209 TSLDSQEGGSTLLPITEQEICVHCEVAADSVPCSHVQSSVLL------QEETSGETEPCNCVATGQIPKSGKSLDVAQDM 1282
Cdd:pfam15376 1181 TSLDSQEGSGGLLPIAEQEICLDCSIAASLESISTEGSKTNCkigepqKEESSGEKEFCSCKAACQIPKYGKAYDFAGDL 1260

                         1290      1300      1310
                   ....*....|....*....|....*....|...
gi 1033837602 1283 HEFPLLNFGEQCLTNMQQEECWWQSSLCSPLFP 1315
Cdd:pfam15376 1261 PEFPLLNIDLQGGTGSQQEECWWQKALCSPLFP 1293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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