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Conserved domains on  [gi|1017483956|ref|NP_001309673|]
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Seven TM Receptor [Caenorhabditis elegans]

Protein Classification

class R serpentine receptor( domain architecture ID 10563422)

class R serpentine receptor, also known as seven TM receptor (Str), belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 41-315 1.63e-84

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402099  Cd Length: 307  Bit Score: 257.77  E-value: 1.63e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956  41 VFITYRILMITFTCSGILFSTFEVVFNPNMFSYNSGTIYFTLSKPFGFGKDVLTVSLVVYTGLYSATTCLIAIQFIYRYW 120
Cdd:pfam10326  30 IFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKSVGQILLALYCGFYGVSISLLAVQFIYRYL 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956 121 AVFDETKLRLFHGWHISIWIIYVLYFGMQWAIGAYNFVKTDQVAKDFFREEIMLRFNASIDDLPALSLVAFDP-SNGS-- 197
Cdd:pfam10326 110 ALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREELLENYNLDIDEVAYVGPVYYPTdENGSkv 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956 198 IRWWNVMTIVNMSFIMSIQYGIIIYCGWSMYSKMEEKIKNYSIVLQKHHNQLFKTLVLQIIAPTVFLLTPLSFIIYLPFF 277
Cdd:pfam10326 190 IRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQLFKALVIQTLIPTILMYIPVGILFLLPLF 269

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1017483956 278 NIKCSLPTGVLLSLFTLYPTADSVVVIYVVTEYRQKLK 315
Cdd:pfam10326 270 NIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 41-315 1.63e-84

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 257.77  E-value: 1.63e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956  41 VFITYRILMITFTCSGILFSTFEVVFNPNMFSYNSGTIYFTLSKPFGFGKDVLTVSLVVYTGLYSATTCLIAIQFIYRYW 120
Cdd:pfam10326  30 IFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKSVGQILLALYCGFYGVSISLLAVQFIYRYL 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956 121 AVFDETKLRLFHGWHISIWIIYVLYFGMQWAIGAYNFVKTDQVAKDFFREEIMLRFNASIDDLPALSLVAFDP-SNGS-- 197
Cdd:pfam10326 110 ALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREELLENYNLDIDEVAYVGPVYYPTdENGSkv 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956 198 IRWWNVMTIVNMSFIMSIQYGIIIYCGWSMYSKMEEKIKNYSIVLQKHHNQLFKTLVLQIIAPTVFLLTPLSFIIYLPFF 277
Cdd:pfam10326 190 IRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQLFKALVIQTLIPTILMYIPVGILFLLPLF 269

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1017483956 278 NIKCSLPTGVLLSLFTLYPTADSVVVIYVVTEYRQKLK 315
Cdd:pfam10326 270 NIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 41-315 1.63e-84

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 257.77  E-value: 1.63e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956  41 VFITYRILMITFTCSGILFSTFEVVFNPNMFSYNSGTIYFTLSKPFGFGKDVLTVSLVVYTGLYSATTCLIAIQFIYRYW 120
Cdd:pfam10326  30 IFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKSVGQILLALYCGFYGVSISLLAVQFIYRYL 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956 121 AVFDETKLRLFHGWHISIWIIYVLYFGMQWAIGAYNFVKTDQVAKDFFREEIMLRFNASIDDLPALSLVAFDP-SNGS-- 197
Cdd:pfam10326 110 ALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREELLENYNLDIDEVAYVGPVYYPTdENGSkv 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956 198 IRWWNVMTIVNMSFIMSIQYGIIIYCGWSMYSKMEEKIKNYSIVLQKHHNQLFKTLVLQIIAPTVFLLTPLSFIIYLPFF 277
Cdd:pfam10326 190 IRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQLFKALVIQTLIPTILMYIPVGILFLLPLF 269

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1017483956 278 NIKCSLPTGVLLSLFTLYPTADSVVVIYVVTEYRQKLK 315
Cdd:pfam10326 270 NIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
 45-314 1.14e-22

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 96.16  E-value: 1.14e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956  45 YRILMITFTCSGILFSTFEVVFNPNMFSYNSGTIYFTLSKPFGFGKDVLTVSLVVYTGLYSATTCLIAIQFIYRYWAVFD 124
Cdd:pfam10319  40 YRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSDGPFFEYSELGQHALSARCSFISASYAVLLIHFIYRYLVLFN 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956 125 ETKL-RLFHGWHISIWIIYVLYFGMQWAIGAYNFVKTDQVAKDFFREEIMLRFNASIDDLPALSLVAFDPSNGSI-RWWN 202
Cdd:pfam10319 120 PQLTrHYFRPWGILISILFFLFHGSVWTAICYFLLRANDEIRDYIREDFRETYGVDSMDINMLGALYWEASDETVfRSWL 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956 203 VMTIVnmSFIMSIQYGIIIYCGWSMYSKMEEKIKNYSIVLQKHHNQLFKTLVLQIIAPTVFLLTPLSFIIYLPFFNIKCS 282
Cdd:pfam10319 200 GILLL--TVISVYSIILYIVLGYKIMRKLNKMSVTMSKKTKRLQKQLLKALIVQTIIPICISFSPCVLAWYSPIFGIDLG 277

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1017483956 283 LPT----GVLLSLFtlyPTADSVVVIYVVTEYRQKL 314
Cdd:pfam10319 278 RWNnyleVIALSAF---PFIDPLAIILCLPVYRNRI 310
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 200-318 1.23e-03

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 40.22  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017483956 200 WWNVMTIVNMSFIMSIQygIIIYCGWSMYSKMEEKIKNYSIVLQKHHNQLFKTLVLQIIAPTVFLLTPLSFIIYLPFFNI 279
Cdd:pfam10318 184 TYFLICIVLLILILIIQ--ILFFVFLTIYYLFKSVKSSLSKKTRKLQKKFFIALIIQVSIPLIVILIPLIYILFSIIFGY 261

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1017483956 280 KCSLPTGVLLSLFTLYPTADSVVVIYVVTEYRQKLKHCF 318
Cdd:pfam10318 262 YNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLF 300
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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