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Conserved domains on  [gi|1017368092|ref|NP_001309541|]
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Uncharacterized protein CELE_C30G12.1 [Caenorhabditis elegans]

Protein Classification

API3 superfamily-containing protein( domain architecture ID 707701)

API3 superfamily-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
API3 super family cl26972
Ascaris pepsin inhibitor-3 (API3); protein inhibitor that reversibly inhibits aspartic ...
 30-132 3.37e-11

Ascaris pepsin inhibitor-3 (API3); protein inhibitor that reversibly inhibits aspartic proteinase cathepsin E, and gastric enzymes pepsin and gastricsin.


The actual alignment was detected with superfamily member cd00225:

Pssm-ID: 474876 [Multi-domain]  Cd Length: 159  Bit Score: 61.51  E-value: 3.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017368092  30 GYVGPA-CAVFDSTLFLHGVSKRKLNDHELHIFSSYQHDLSAFK--------------------DSSSSFDSFEASFPTI 88
Cdd:cd00225     7 GGGGSAgCVVTDNVLFANGFPLRELTPDEQQELAQYVEDVADYKeevkqalkerqeglklrragKKKKAVTLAEEKLPKA 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1017368092  89 PK---FCGGyDDSIEVVLDSCIVRNNHVYVGDHLIRPLTNFEKQKIQ 132
Cdd:cd00225    87 PKkpsFCSP-DDTTQFYFDGCMVQNNKVYVGNTYARDLTPKEIAELK 132
 
Name Accession Description Interval E-value
API3 cd00225
Ascaris pepsin inhibitor-3 (API3); protein inhibitor that reversibly inhibits aspartic ...
 30-132 3.37e-11

Ascaris pepsin inhibitor-3 (API3); protein inhibitor that reversibly inhibits aspartic proteinase cathepsin E, and gastric enzymes pepsin and gastricsin.


Pssm-ID: 119406 [Multi-domain]  Cd Length: 159  Bit Score: 61.51  E-value: 3.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017368092  30 GYVGPA-CAVFDSTLFLHGVSKRKLNDHELHIFSSYQHDLSAFK--------------------DSSSSFDSFEASFPTI 88
Cdd:cd00225     7 GGGGSAgCVVTDNVLFANGFPLRELTPDEQQELAQYVEDVADYKeevkqalkerqeglklrragKKKKAVTLAEEKLPKA 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1017368092  89 PK---FCGGyDDSIEVVLDSCIVRNNHVYVGDHLIRPLTNFEKQKIQ 132
Cdd:cd00225    87 PKkpsFCSP-DDTTQFYFDGCMVQNNKVYVGNTYARDLTPKEIAELK 132
 
Name Accession Description Interval E-value
API3 cd00225
Ascaris pepsin inhibitor-3 (API3); protein inhibitor that reversibly inhibits aspartic ...
 30-132 3.37e-11

Ascaris pepsin inhibitor-3 (API3); protein inhibitor that reversibly inhibits aspartic proteinase cathepsin E, and gastric enzymes pepsin and gastricsin.


Pssm-ID: 119406 [Multi-domain]  Cd Length: 159  Bit Score: 61.51  E-value: 3.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017368092  30 GYVGPA-CAVFDSTLFLHGVSKRKLNDHELHIFSSYQHDLSAFK--------------------DSSSSFDSFEASFPTI 88
Cdd:cd00225     7 GGGGSAgCVVTDNVLFANGFPLRELTPDEQQELAQYVEDVADYKeevkqalkerqeglklrragKKKKAVTLAEEKLPKA 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1017368092  89 PK---FCGGyDDSIEVVLDSCIVRNNHVYVGDHLIRPLTNFEKQKIQ 132
Cdd:cd00225    87 PKkpsFCSP-DDTTQFYFDGCMVQNNKVYVGNTYARDLTPKEIAELK 132
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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