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Conserved domains on  [gi|1017461076|ref|NP_001309461|]
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Seven TM Receptor [Caenorhabditis elegans]

Protein Classification

class R serpentine receptor( domain architecture ID 10563422)

class R serpentine receptor, also known as seven TM receptor (Str), belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
9-315 1.86e-97

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402099  Cd Length: 307  Bit Score: 291.28  E-value: 1.86e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076   9 ADVISYSAYFVTLALNSTLIYLTKYCSTRLTIIYRRMIIGFAVFGIGFSTLDIVVRPIMHSYNGCFLYFSLKGSFRSSKA 88
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076  89 ITEMLLAIYSAVYAAILSFLTIQYIYRVCVLRCPQLVQYFRGWRFILWLGYVFMFGLAWGVITYFYAYPDEYARDYVREE 168
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076 169 MYEQYKVDSDKVALFVLLAYGEN-NGTKFVRPQSLICIFGQMGIMSLQYMIMMICGILIYKQIKaDLKETTMILNSKFQK 247
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPTDeNGSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMK-KLKSLGSEKTRKLQK 239
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1017461076 248 QIFNALLYQLVAPSLLVHLPAVPLFFAPFFDMKFSFRTRVVVYFFSVYPLLDSLILLTVVSDYRLAVR 315
Cdd:pfam10326 240 QLFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
9-315 1.86e-97

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 291.28  E-value: 1.86e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076   9 ADVISYSAYFVTLALNSTLIYLTKYCSTRLTIIYRRMIIGFAVFGIGFSTLDIVVRPIMHSYNGCFLYFSLKGSFRSSKA 88
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076  89 ITEMLLAIYSAVYAAILSFLTIQYIYRVCVLRCPQLVQYFRGWRFILWLGYVFMFGLAWGVITYFYAYPDEYARDYVREE 168
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076 169 MYEQYKVDSDKVALFVLLAYGEN-NGTKFVRPQSLICIFGQMGIMSLQYMIMMICGILIYKQIKaDLKETTMILNSKFQK 247
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPTDeNGSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMK-KLKSLGSEKTRKLQK 239
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1017461076 248 QIFNALLYQLVAPSLLVHLPAVPLFFAPFFDMKFSFRTRVVVYFFSVYPLLDSLILLTVVSDYRLAVR 315
Cdd:pfam10326 240 QLFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
9-315 1.86e-97

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 291.28  E-value: 1.86e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076   9 ADVISYSAYFVTLALNSTLIYLTKYCSTRLTIIYRRMIIGFAVFGIGFSTLDIVVRPIMHSYNGCFLYFSLKGSFRSSKA 88
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076  89 ITEMLLAIYSAVYAAILSFLTIQYIYRVCVLRCPQLVQYFRGWRFILWLGYVFMFGLAWGVITYFYAYPDEYARDYVREE 168
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076 169 MYEQYKVDSDKVALFVLLAYGEN-NGTKFVRPQSLICIFGQMGIMSLQYMIMMICGILIYKQIKaDLKETTMILNSKFQK 247
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPTDeNGSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMK-KLKSLGSEKTRKLQK 239
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1017461076 248 QIFNALLYQLVAPSLLVHLPAVPLFFAPFFDMKFSFRTRVVVYFFSVYPLLDSLILLTVVSDYRLAVR 315
Cdd:pfam10326 240 QLFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
23-311 1.06e-27

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 110.41  E-value: 1.06e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076  23 LNSTLIYLTKYCSTRLTIIYRRMIIGFAVFGIGFSTLDIVVRPIMHSYNGCFLYFSLKGSFRSSKAITEMLLAIYSAVYA 102
Cdd:pfam10319  21 VNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSDGPFFEYSELGQHALSARCSFIS 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076 103 AILSFLTIQYIYRVCVLRCPQLV-QYFRGWRFILWLGYVFMFGLAWGVITYFYAYPDEYARDYVREEMYEQYKVDSDKVA 181
Cdd:pfam10319 101 ASYAVLLIHFIYRYLVLFNPQLTrHYFRPWGILISILFFLFHGSVWTAICYFLLRANDEIRDYIREDFRETYGVDSMDIN 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017461076 182 LFVLLAYGENNGTKFvrpQSLICIfgqmGIMSLQYMIMMICGILIYKQIKADLKETTMILN---SKFQKQIFNALLYQLV 258
Cdd:pfam10319 181 MLGALYWEASDETVF---RSWLGI----LLLTVISVYSIILYIVLGYKIMRKLNKMSVTMSkktKRLQKQLLKALIVQTI 253
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1017461076 259 APSLLVHLPAVPLFFAPFFDMKFsfrTRVVVYF----FSVYPLLDSLILLTVVSDYR 311
Cdd:pfam10319 254 IPICISFSPCVLAWYSPIFGIDL---GRWNNYLeviaLSAFPFIDPLAIILCLPVYR 307
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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