large ribosomal subunit protein uL18m isoform 2 [Homo sapiens]
Protein Classification
uL18 family ribosomal protein( domain architecture ID 227)
uL18 family ribosomal protein such as bacteria 50S ribosomal protein L18, chloroplast 50S ribosomal protein L18, and mitochondrial 39S ribosomal protein L18.
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| Ribosomal_L18_L5e super family | cl00379 | Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of ... |
68-109 | 3.16e-10 | ||
Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA depends on the binding of L18 and L5 to 5S rRNA. L18/L5e is generally described as L18 in prokaryotes and archaea, and as L5e (or L5) in eukaryotes. In bacteria, the CP proteins L5, L18, and L25 are required for the ribosome to incorporate 5S rRNA into the large subunit, one of the last steps in ribosome assembly. In archaea, both L18 and L5 bind 5S rRNA; in eukaryotes, only the L18 homolog (L5e) binds 5S rRNA but a homolog to L5 is also identified. The actual alignment was detected with superfamily member cd00432: Pssm-ID: 444873 Cd Length: 103 Bit Score: 53.31 E-value: 3.16e-10
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| Name | Accession | Description | Interval | E-value | ||
| Ribosomal_L18_L5e | cd00432 | Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of ... |
68-109 | 3.16e-10 | ||
Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA depends on the binding of L18 and L5 to 5S rRNA. L18/L5e is generally described as L18 in prokaryotes and archaea, and as L5e (or L5) in eukaryotes. In bacteria, the CP proteins L5, L18, and L25 are required for the ribosome to incorporate 5S rRNA into the large subunit, one of the last steps in ribosome assembly. In archaea, both L18 and L5 bind 5S rRNA; in eukaryotes, only the L18 homolog (L5e) binds 5S rRNA but a homolog to L5 is also identified. Pssm-ID: 238246 Cd Length: 103 Bit Score: 53.31 E-value: 3.16e-10
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| Name | Accession | Description | Interval | E-value | ||
| Ribosomal_L18_L5e | cd00432 | Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of ... |
68-109 | 3.16e-10 | ||
Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA depends on the binding of L18 and L5 to 5S rRNA. L18/L5e is generally described as L18 in prokaryotes and archaea, and as L5e (or L5) in eukaryotes. In bacteria, the CP proteins L5, L18, and L25 are required for the ribosome to incorporate 5S rRNA into the large subunit, one of the last steps in ribosome assembly. In archaea, both L18 and L5 bind 5S rRNA; in eukaryotes, only the L18 homolog (L5e) binds 5S rRNA but a homolog to L5 is also identified. Pssm-ID: 238246 Cd Length: 103 Bit Score: 53.31 E-value: 3.16e-10
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