integrin alpha-5 isoform 2 [Mus musculus]
integrin alpha( domain architecture ID 12192630)
integrin alpha forms a heterodimer with integrin beta to mediate cell-extracellular matrix and cell-cell interactions; integrin alpha is a component of integrin, a cell adhesion molecule that mediates cell-extracellular matrix and cell-cell interactions
List of domain hits
Name | Accession | Description | Interval | E-value | |||||||
Integrin_alpha2 | pfam08441 | Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C ... |
169-597 | 0e+00 | |||||||
Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains. : Pssm-ID: 462478 [Multi-domain] Cd Length: 449 Bit Score: 553.47 E-value: 0e+00
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Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
68-122 | 1.82e-15 | |||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 70.87 E-value: 1.82e-15
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Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
1-58 | 8.76e-13 | |||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 63.55 E-value: 8.76e-13
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Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
134-186 | 6.69e-06 | |||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 43.90 E-value: 6.69e-06
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Name | Accession | Description | Interval | E-value | |||||||
Integrin_alpha2 | pfam08441 | Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C ... |
169-597 | 0e+00 | |||||||
Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains. Pssm-ID: 462478 [Multi-domain] Cd Length: 449 Bit Score: 553.47 E-value: 0e+00
|
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Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
68-122 | 1.82e-15 | |||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 70.87 E-value: 1.82e-15
|
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Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
1-58 | 8.76e-13 | |||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 63.55 E-value: 8.76e-13
|
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FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
5-47 | 3.23e-09 | |||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 52.51 E-value: 3.23e-09
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FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
71-107 | 4.55e-09 | |||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 52.13 E-value: 4.55e-09
|
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Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
134-186 | 6.69e-06 | |||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 43.90 E-value: 6.69e-06
|
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FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
135-157 | 8.98e-03 | |||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 34.41 E-value: 8.98e-03
|
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Name | Accession | Description | Interval | E-value | |||||||
Integrin_alpha2 | pfam08441 | Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C ... |
169-597 | 0e+00 | |||||||
Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains. Pssm-ID: 462478 [Multi-domain] Cd Length: 449 Bit Score: 553.47 E-value: 0e+00
|
|||||||||||
Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
68-122 | 1.82e-15 | |||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 70.87 E-value: 1.82e-15
|
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Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
1-58 | 8.76e-13 | |||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 63.55 E-value: 8.76e-13
|
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FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
5-47 | 3.23e-09 | |||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 52.51 E-value: 3.23e-09
|
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FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
71-107 | 4.55e-09 | |||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 52.13 E-value: 4.55e-09
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FG-GAP_3 | pfam13517 | FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ... |
13-91 | 2.18e-06 | |||||||
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses. Pssm-ID: 433275 [Multi-domain] Cd Length: 61 Bit Score: 45.29 E-value: 2.18e-06
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Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
134-186 | 6.69e-06 | |||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 43.90 E-value: 6.69e-06
|
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FG-GAP_3 | pfam13517 | FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ... |
80-155 | 1.42e-03 | |||||||
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses. Pssm-ID: 433275 [Multi-domain] Cd Length: 61 Bit Score: 37.59 E-value: 1.42e-03
|
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FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
135-157 | 8.98e-03 | |||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 34.41 E-value: 8.98e-03
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Blast search parameters | ||||
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