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Conserved domains on  [gi|922581638|ref|NP_001300328|]
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Calponin-homology (CH) domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2169-2263 8.72e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 8.72e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   2169 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2248
Cdd:smart00557    1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581638   2249 EHVPGSPFLVMIVDT 2263
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2075-2166 6.64e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.90  E-value: 6.64e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   2075 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2153
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581638   2154 VKGSPFVVHVSLP 2166
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1980-2069 1.09e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.09e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1980 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2058
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|.
gi 922581638   2059 VKGSPFAVSAD 2069
Cdd:smart00557   81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1245-1328 5.30e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.81  E-value: 5.30e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1245 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVCEGR---VPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1319
Cdd:smart00557    1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                    ....*....
gi 922581638   1320 VPGSPFLCQ 1328
Cdd:smart00557   81 IPGSPFTVK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
999-1092 1.25e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 1.25e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638    999 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1077
Cdd:smart00557    1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581638   1078 EVLKNSPFEVNIVDA 1092
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
160-244 7.33e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 80.34  E-value: 7.33e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638    160 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 236
Cdd:smart00557    5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*...
gi 922581638    237 PIKVEILP 244
Cdd:smart00557   85 PFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1156-1245 4.57e-17

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 78.41  E-value: 4.57e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1156 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1231
Cdd:smart00557    1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 922581638   1232 PVTGSPFTCRAYDP 1245
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1435-1514 1.35e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.35e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1435 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1513
Cdd:smart00557   13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92

                    .
gi 922581638   1514 A 1514
Cdd:smart00557   93 A 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
68-153 1.41e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.41e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638     68 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 147
Cdd:smart00557    3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                    ....*.
gi 922581638    148 GSPLSV 153
Cdd:smart00557   83 GSPFTV 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1579-1660 1.65e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.49  E-value: 1.65e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1579 LNSAQIGQKKGFTIDNINK-SSDCNVIITDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPGSPFKTEV 1657
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ...
gi 922581638   1658 IDP 1660
Cdd:smart00557   91 GPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1756-1843 1.03e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.56  E-value: 1.03e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1756 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 1834
Cdd:smart00557    6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581638   1835 PFTVNVVDP 1843
Cdd:smart00557   85 PFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1342-1425 9.77e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 71.48  E-value: 9.77e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1342 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1420
Cdd:smart00557   11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88

                    ....*
gi 922581638   1421 KAYDA 1425
Cdd:smart00557   89 KVGPA 93
IG_FLMN super family cl42963
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1677-1750 2.82e-10

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


The actual alignment was detected with superfamily member smart00557:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 58.77  E-value: 2.82e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581638   1677 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 1750
Cdd:smart00557   19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
IG_FLMN super family cl42963
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1862-1938 2.55e-09

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


The actual alignment was detected with superfamily member smart00557:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 56.07  E-value: 2.55e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581638   1862 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 1938
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
IG_FLMN super family cl42963
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
4-53 1.18e-07

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


The actual alignment was detected with superfamily member smart00557:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 51.45  E-value: 1.18e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|
gi 922581638      4 GGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPVED 53
Cdd:smart00557   43 GKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
PTZ00121 super family cl31754
MAEBL; Provisional
584-1006 3.08e-05

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 3.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  584 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 663
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  664 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 740
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  741 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV--------- 811
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakka 1670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  812 -----------KSEDDKILAKHGFTRKPEPSIEIqepvtEQIRDDVVETAIAPEvPLRPVEELPHSPAPSSRSTPATTPK 880
Cdd:PTZ00121 1671 eedkkkaeeakKAEEDEKKAAEALKKEAEEAKKA-----EELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKK 1744
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  881 LSAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKS 960
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDI 1803
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 922581638  961 SSKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1006
Cdd:PTZ00121 1804 FDNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2169-2263 8.72e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 8.72e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   2169 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2248
Cdd:smart00557    1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581638   2249 EHVPGSPFLVMIVDT 2263
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
2166-2256 1.03e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 94.28  E-value: 1.03e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  2166 PPDPSKVRVYGPGVEHGILSLfKSNFVVETRGAGaGQLTVRVRGPKGAFnVEMQREKKNERTIHCKYEPKEPGDYQVEVK 2245
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGK-PAEFTVDTRDAG-GEGEVEVTGPDGSP-VPVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|.
gi 922581638  2246 WHGEHVPGSPF 2256
Cdd:pfam00630   78 FNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2075-2166 6.64e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.90  E-value: 6.64e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   2075 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2153
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581638   2154 VKGSPFVVHVSLP 2166
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1980-2069 1.09e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.09e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1980 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2058
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|.
gi 922581638   2059 VKGSPFAVSAD 2069
Cdd:smart00557   81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1245-1328 5.30e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.81  E-value: 5.30e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1245 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVCEGR---VPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1319
Cdd:smart00557    1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                    ....*....
gi 922581638   1320 VPGSPFLCQ 1328
Cdd:smart00557   81 IPGSPFTVK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
999-1092 1.25e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 1.25e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638    999 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1077
Cdd:smart00557    1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581638   1078 EVLKNSPFEVNIVDA 1092
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
160-244 7.33e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 80.34  E-value: 7.33e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638    160 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 236
Cdd:smart00557    5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*...
gi 922581638    237 PIKVEILP 244
Cdd:smart00557   85 PFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1156-1245 4.57e-17

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 78.41  E-value: 4.57e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1156 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1231
Cdd:smart00557    1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 922581638   1232 PVTGSPFTCRAYDP 1245
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1435-1514 1.35e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.35e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1435 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1513
Cdd:smart00557   13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92

                    .
gi 922581638   1514 A 1514
Cdd:smart00557   93 A 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
68-153 1.41e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.41e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638     68 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 147
Cdd:smart00557    3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                    ....*.
gi 922581638    148 GSPLSV 153
Cdd:smart00557   83 GSPFTV 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1579-1660 1.65e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.49  E-value: 1.65e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1579 LNSAQIGQKKGFTIDNINK-SSDCNVIITDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPGSPFKTEV 1657
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ...
gi 922581638   1658 IDP 1660
Cdd:smart00557   91 GPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1579-1654 2.39e-16

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 76.17  E-value: 2.39e-16
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581638  1579 LNSAQIGQKKGFTIDNINKSSDCNVIITDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPGSPFK 1654
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1756-1843 1.03e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.56  E-value: 1.03e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1756 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 1834
Cdd:smart00557    6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581638   1835 PFTVNVVDP 1843
Cdd:smart00557   85 PFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1342-1425 9.77e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 71.48  E-value: 9.77e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1342 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1420
Cdd:smart00557   11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88

                    ....*
gi 922581638   1421 KAYDA 1425
Cdd:smart00557   89 KVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1756-1837 3.98e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 69.63  E-value: 3.98e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1756 VYGAAVDQSiKIGEPASLIFDPKKTNGGLKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGSP 1835
Cdd:pfam00630    9 ASGPGLEPG-VVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581638  1836 FT 1837
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1422-1506 8.51e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.85  E-value: 8.51e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1422 AYDARKTVLVPPA--NAVVGKPATFVIDAARSGAGNMEIIVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNG 1499
Cdd:pfam00630    1 AADASKVKASGPGlePGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*..
gi 922581638  1500 ISVPGSP 1506
Cdd:pfam00630   81 QHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
1980-2064 1.21e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.47  E-value: 1.21e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1980 SRIMVRGDGLHRAVLKEHNEFIIDGSDinKEGRITATLLGSK-ADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2058
Cdd:pfam00630    5 SKVKASGPGLEPGVVGKPAEFTVDTRD--AGGEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQH 82

                   ....*.
gi 922581638  2059 VKGSPF 2064
Cdd:pfam00630   83 IPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1242-1325 2.13e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 67.70  E-value: 2.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1242 AYDPAKIKVG--AIPKGLLDKPVYFTVDASEAGvGNLEVAVCE---GRVPSMAHALGHHKYDISFVPKEDVDHTITVRFN 1316
Cdd:pfam00630    1 AADASKVKASgpGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGpdgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*....
gi 922581638  1317 NEPVPGSPF 1325
Cdd:pfam00630   80 GQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
160-239 2.14e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 65.00  E-value: 2.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   160 KVRLEPLGGGVPKQPVQFYVDAVEA-GKGQLEISVNQGK-VPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGCP 237
Cdd:pfam00630    8 KASGPGLEPGVVGKPAEFTVDTRDAgGEGEVEVTGPDGSpVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581638   238 IK 239
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
69-150 6.90e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 63.46  E-value: 6.90e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638    69 SELSGPGLVRAPVNRTAQFDITGEGlELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVDG 148
Cdd:pfam00630    7 VKASGPGLEPGVVGKPAEFTVDTRD-AGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85

                   ..
gi 922581638   149 SP 150
Cdd:pfam00630   86 SP 87
Filamin pfam00630
Filamin/ABP280 repeat;
996-1086 1.38e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 62.69  E-value: 1.38e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   996 VYDASEIIV-GEIPNQSNLNDTVEFTVDAGRAGfGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNIT 1074
Cdd:pfam00630    1 AADASKVKAsGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGT--YTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|..
gi 922581638  1075 FNKEVLKNSPFE 1086
Cdd:pfam00630   78 FNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1169-1239 8.71e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 8.71e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581638  1169 RVGQPSSLVVEVSGHD-QLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGVPVTGSPFT 1239
Cdd:pfam00630   18 VVGKPAEFTVDTRDAGgEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1342-1419 1.88e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 59.22  E-value: 1.88e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581638  1342 LERIPVDEETEIQILTDEIDSAPEARVRDPQGNDLPVNVTrSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFT 1419
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVT-DNGDGT-YTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1677-1750 2.82e-10

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 58.77  E-value: 2.82e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581638   1677 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 1750
Cdd:smart00557   19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
2085-2160 3.58e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 58.45  E-value: 3.58e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 922581638  2085 LKIGIINENIKTLIDTRRAGsGQLSALCMGPN-KPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEHVKGSPFV 2160
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1657-1743 7.31e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 57.68  E-value: 7.31e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1657 VIDPKNVEIRGLS-DQVLLRHATTINVDRRNAGnGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVA 1735
Cdd:pfam00630    1 AADASKVKASGPGlEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*...
gi 922581638  1736 GFQIPGYP 1743
Cdd:pfam00630   80 GQHIPGSP 87
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1862-1938 2.55e-09

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 56.07  E-value: 2.55e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581638   1862 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 1938
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
1840-1930 1.88e-08

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 53.45  E-value: 1.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1840 VVDPTKVIVNDLDMDRDgtlllRLGHSNSFDVDATAAGpGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKY 1919
Cdd:pfam00630    1 AADASKVKASGPGLEPG-----VVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVP--VEVTDNGDGTYTVSYTPTEPGDY 72
                           90
                   ....*....|.
gi 922581638  1920 SIYLYWNELPV 1930
Cdd:pfam00630   73 TVSVKFNGQHI 83
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
4-53 1.18e-07

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 51.45  E-value: 1.18e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|
gi 922581638      4 GGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPVED 53
Cdd:smart00557   43 GKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
3-48 1.51e-06

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 48.05  E-value: 1.51e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 922581638     3 NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWK 48
Cdd:pfam00630   44 DGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
PTZ00121 PTZ00121
MAEBL; Provisional
584-1006 3.08e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 3.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  584 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 663
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  664 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 740
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  741 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV--------- 811
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakka 1670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  812 -----------KSEDDKILAKHGFTRKPEPSIEIqepvtEQIRDDVVETAIAPEvPLRPVEELPHSPAPSSRSTPATTPK 880
Cdd:PTZ00121 1671 eedkkkaeeakKAEEDEKKAAEALKKEAEEAKKA-----EELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKK 1744
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  881 LSAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKS 960
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDI 1803
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 922581638  961 SSKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1006
Cdd:PTZ00121 1804 FDNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
912-999 4.07e-05

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 44.13  E-value: 4.07e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638    912 GKEVEVKLEGIKLGkEDQLRVVVLPPANKaipganggpptEVDTKVK-KSSSKYEISFKPTEVGTHKVFAYVNDMQHPLS 990
Cdd:smart00557   17 GEPAEFTVDTRDAG-GGELEVEVTGPSGK-----------KVPVEVKdNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581638    991 PFAVRVYDA 999
Cdd:smart00557   85 PFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
942-992 4.91e-04

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 41.12  E-value: 4.91e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 922581638   942 IPGANGGP-PTEVdtkVKKSSSKYEISFKPTEVGTHKVFAYVNDMQHPLSPF 992
Cdd:pfam00630   40 VTGPDGSPvPVEV---TDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2169-2263 8.72e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 8.72e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   2169 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2248
Cdd:smart00557    1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581638   2249 EHVPGSPFLVMIVDT 2263
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
2166-2256 1.03e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 94.28  E-value: 1.03e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  2166 PPDPSKVRVYGPGVEHGILSLfKSNFVVETRGAGaGQLTVRVRGPKGAFnVEMQREKKNERTIHCKYEPKEPGDYQVEVK 2245
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGK-PAEFTVDTRDAG-GEGEVEVTGPDGSP-VPVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|.
gi 922581638  2246 WHGEHVPGSPF 2256
Cdd:pfam00630   78 FNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2075-2166 6.64e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.90  E-value: 6.64e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   2075 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2153
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581638   2154 VKGSPFVVHVSLP 2166
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1980-2069 1.09e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.09e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1980 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2058
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|.
gi 922581638   2059 VKGSPFAVSAD 2069
Cdd:smart00557   81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1245-1328 5.30e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.81  E-value: 5.30e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1245 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVCEGR---VPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1319
Cdd:smart00557    1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                    ....*....
gi 922581638   1320 VPGSPFLCQ 1328
Cdd:smart00557   81 IPGSPFTVK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
999-1092 1.25e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 1.25e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638    999 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1077
Cdd:smart00557    1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581638   1078 EVLKNSPFEVNIVDA 1092
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
160-244 7.33e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 80.34  E-value: 7.33e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638    160 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 236
Cdd:smart00557    5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*...
gi 922581638    237 PIKVEILP 244
Cdd:smart00557   85 PFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1156-1245 4.57e-17

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 78.41  E-value: 4.57e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1156 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1231
Cdd:smart00557    1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 922581638   1232 PVTGSPFTCRAYDP 1245
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1435-1514 1.35e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.35e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1435 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1513
Cdd:smart00557   13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92

                    .
gi 922581638   1514 A 1514
Cdd:smart00557   93 A 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
68-153 1.41e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.41e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638     68 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 147
Cdd:smart00557    3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                    ....*.
gi 922581638    148 GSPLSV 153
Cdd:smart00557   83 GSPFTV 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1579-1660 1.65e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.49  E-value: 1.65e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1579 LNSAQIGQKKGFTIDNINK-SSDCNVIITDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPGSPFKTEV 1657
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ...
gi 922581638   1658 IDP 1660
Cdd:smart00557   91 GPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1579-1654 2.39e-16

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 76.17  E-value: 2.39e-16
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581638  1579 LNSAQIGQKKGFTIDNINKSSDCNVIITDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPGSPFK 1654
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1756-1843 1.03e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.56  E-value: 1.03e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1756 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 1834
Cdd:smart00557    6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581638   1835 PFTVNVVDP 1843
Cdd:smart00557   85 PFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1342-1425 9.77e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 71.48  E-value: 9.77e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   1342 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1420
Cdd:smart00557   11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88

                    ....*
gi 922581638   1421 KAYDA 1425
Cdd:smart00557   89 KVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1756-1837 3.98e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 69.63  E-value: 3.98e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1756 VYGAAVDQSiKIGEPASLIFDPKKTNGGLKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGSP 1835
Cdd:pfam00630    9 ASGPGLEPG-VVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581638  1836 FT 1837
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1422-1506 8.51e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.85  E-value: 8.51e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1422 AYDARKTVLVPPA--NAVVGKPATFVIDAARSGAGNMEIIVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNG 1499
Cdd:pfam00630    1 AADASKVKASGPGlePGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*..
gi 922581638  1500 ISVPGSP 1506
Cdd:pfam00630   81 QHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
1980-2064 1.21e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.47  E-value: 1.21e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1980 SRIMVRGDGLHRAVLKEHNEFIIDGSDinKEGRITATLLGSK-ADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2058
Cdd:pfam00630    5 SKVKASGPGLEPGVVGKPAEFTVDTRD--AGGEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQH 82

                   ....*.
gi 922581638  2059 VKGSPF 2064
Cdd:pfam00630   83 IPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1242-1325 2.13e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 67.70  E-value: 2.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1242 AYDPAKIKVG--AIPKGLLDKPVYFTVDASEAGvGNLEVAVCE---GRVPSMAHALGHHKYDISFVPKEDVDHTITVRFN 1316
Cdd:pfam00630    1 AADASKVKASgpGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGpdgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*....
gi 922581638  1317 NEPVPGSPF 1325
Cdd:pfam00630   80 GQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
160-239 2.14e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 65.00  E-value: 2.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   160 KVRLEPLGGGVPKQPVQFYVDAVEA-GKGQLEISVNQGK-VPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGCP 237
Cdd:pfam00630    8 KASGPGLEPGVVGKPAEFTVDTRDAgGEGEVEVTGPDGSpVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581638   238 IK 239
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
69-150 6.90e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 63.46  E-value: 6.90e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638    69 SELSGPGLVRAPVNRTAQFDITGEGlELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVDG 148
Cdd:pfam00630    7 VKASGPGLEPGVVGKPAEFTVDTRD-AGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85

                   ..
gi 922581638   149 SP 150
Cdd:pfam00630   86 SP 87
Filamin pfam00630
Filamin/ABP280 repeat;
996-1086 1.38e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 62.69  E-value: 1.38e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638   996 VYDASEIIV-GEIPNQSNLNDTVEFTVDAGRAGfGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNIT 1074
Cdd:pfam00630    1 AADASKVKAsGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGT--YTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|..
gi 922581638  1075 FNKEVLKNSPFE 1086
Cdd:pfam00630   78 FNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1169-1239 8.71e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 8.71e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581638  1169 RVGQPSSLVVEVSGHD-QLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGVPVTGSPFT 1239
Cdd:pfam00630   18 VVGKPAEFTVDTRDAGgEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1342-1419 1.88e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 59.22  E-value: 1.88e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581638  1342 LERIPVDEETEIQILTDEIDSAPEARVRDPQGNDLPVNVTrSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFT 1419
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVT-DNGDGT-YTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1677-1750 2.82e-10

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 58.77  E-value: 2.82e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581638   1677 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 1750
Cdd:smart00557   19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
2085-2160 3.58e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 58.45  E-value: 3.58e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 922581638  2085 LKIGIINENIKTLIDTRRAGsGQLSALCMGPN-KPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEHVKGSPFV 2160
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1657-1743 7.31e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 57.68  E-value: 7.31e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1657 VIDPKNVEIRGLS-DQVLLRHATTINVDRRNAGnGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVA 1735
Cdd:pfam00630    1 AADASKVKASGPGlEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*...
gi 922581638  1736 GFQIPGYP 1743
Cdd:pfam00630   80 GQHIPGSP 87
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1862-1938 2.55e-09

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 56.07  E-value: 2.55e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581638   1862 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 1938
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
1840-1930 1.88e-08

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 53.45  E-value: 1.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  1840 VVDPTKVIVNDLDMDRDgtlllRLGHSNSFDVDATAAGpGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKY 1919
Cdd:pfam00630    1 AADASKVKASGPGLEPG-----VVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVP--VEVTDNGDGTYTVSYTPTEPGDY 72
                           90
                   ....*....|.
gi 922581638  1920 SIYLYWNELPV 1930
Cdd:pfam00630   73 TVSVKFNGQHI 83
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
4-53 1.18e-07

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 51.45  E-value: 1.18e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|
gi 922581638      4 GGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPVED 53
Cdd:smart00557   43 GKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
3-48 1.51e-06

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 48.05  E-value: 1.51e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 922581638     3 NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWK 48
Cdd:pfam00630   44 DGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
PTZ00121 PTZ00121
MAEBL; Provisional
584-1006 3.08e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 3.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  584 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 663
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  664 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 740
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  741 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV--------- 811
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakka 1670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  812 -----------KSEDDKILAKHGFTRKPEPSIEIqepvtEQIRDDVVETAIAPEvPLRPVEELPHSPAPSSRSTPATTPK 880
Cdd:PTZ00121 1671 eedkkkaeeakKAEEDEKKAAEALKKEAEEAKKA-----EELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKK 1744
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638  881 LSAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKS 960
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDI 1803
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 922581638  961 SSKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1006
Cdd:PTZ00121 1804 FDNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
912-999 4.07e-05

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 44.13  E-value: 4.07e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581638    912 GKEVEVKLEGIKLGkEDQLRVVVLPPANKaipganggpptEVDTKVK-KSSSKYEISFKPTEVGTHKVFAYVNDMQHPLS 990
Cdd:smart00557   17 GEPAEFTVDTRDAG-GGELEVEVTGPSGK-----------KVPVEVKdNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581638    991 PFAVRVYDA 999
Cdd:smart00557   85 PFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
942-992 4.91e-04

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 41.12  E-value: 4.91e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 922581638   942 IPGANGGP-PTEVdtkVKKSSSKYEISFKPTEVGTHKVFAYVNDMQHPLSPF 992
Cdd:pfam00630   40 VTGPDGSPvPVEV---TDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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