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Conserved domains on  [gi|922581634|ref|NP_001300326|]
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Calponin-homology (CH) domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2313-2407 8.92e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 8.92e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   2313 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2392
Cdd:smart00557    1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581634   2393 EHVPGSPFLVMIVDT 2407
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2219-2310 6.85e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.90  E-value: 6.85e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   2219 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2297
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581634   2298 VKGSPFVVHVSLP 2310
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
15-107 1.43e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.13  E-value: 1.43e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634     15 ASSVSVYGENLRSASVGKTASFMVHAIGAEAKDISAHVTVPSGGKFPAKVVTLDDVTFQIEWTPKEPGEHSVDVMLADQR 94
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581634     95 VPDAPFACNVGAP 107
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2124-2213 1.13e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.13e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   2124 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2202
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|.
gi 922581634   2203 VKGSPFAVSAD 2213
Cdd:smart00557   81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1389-1472 5.52e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.81  E-value: 5.52e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1389 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVCEGR---VPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1463
Cdd:smart00557    1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                    ....*....
gi 922581634   1464 VPGSPFLCQ 1472
Cdd:smart00557   81 IPGSPFTVK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1143-1236 1.30e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 1.30e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1143 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1221
Cdd:smart00557    1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581634   1222 EVLKNSPFEVNIVDA 1236
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
304-388 7.64e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 80.73  E-value: 7.64e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    304 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 380
Cdd:smart00557    5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*...
gi 922581634    381 PIKVEILP 388
Cdd:smart00557   85 PFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1300-1389 4.81e-17

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 78.41  E-value: 4.81e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1300 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1375
Cdd:smart00557    1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 922581634   1376 PVTGSPFTCRAYDP 1389
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1579-1658 1.40e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.40e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1579 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1657
Cdd:smart00557   13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92

                    .
gi 922581634   1658 A 1658
Cdd:smart00557   93 A 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
212-297 1.49e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.49e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    212 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 291
Cdd:smart00557    3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                    ....*.
gi 922581634    292 GSPLSV 297
Cdd:smart00557   83 GSPFTV 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1723-1804 1.74e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.49  E-value: 1.74e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1723 LNSAQIGQKKGFTIDNINK-SSDCNVIITDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPGSPFKTEV 1801
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ...
gi 922581634   1802 IDP 1804
Cdd:smart00557   91 GPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1900-1987 1.08e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.56  E-value: 1.08e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1900 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 1978
Cdd:smart00557    6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581634   1979 PFTVNVVDP 1987
Cdd:smart00557   85 PFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1486-1569 1.03e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 71.48  E-value: 1.03e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1486 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1564
Cdd:smart00557   11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88

                    ....*
gi 922581634   1565 KAYDA 1569
Cdd:smart00557   89 KVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
119-197 1.90e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 70.71  E-value: 1.90e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    119 IQPSKLHTDHSFEIDASAAGSGNLEIMI---NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPV 195
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ..
gi 922581634    196 ED 197
Cdd:smart00557   91 GP 92
IG_FLMN super family cl42963
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1821-1894 2.94e-10

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


The actual alignment was detected with superfamily member smart00557:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 58.77  E-value: 2.94e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581634   1821 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 1894
Cdd:smart00557   19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
IG_FLMN super family cl42963
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2006-2082 2.63e-09

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


The actual alignment was detected with superfamily member smart00557:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 56.07  E-value: 2.63e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581634   2006 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 2082
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
PTZ00121 super family cl31754
MAEBL; Provisional
728-1150 2.35e-05

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 2.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  728 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 807
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  808 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 884
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  885 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV--------- 955
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakka 1670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  956 -----------KSEDDKILAKHGFTRKPEPSIEIqepvtEQIRDDVVETAIAPEvPLRPVEELPHSPAPSSRSTPATTPK 1024
Cdd:PTZ00121 1671 eedkkkaeeakKAEEDEKKAAEALKKEAEEAKKA-----EELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKK 1744
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634 1025 LSAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKS 1104
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDI 1803
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 922581634 1105 SSKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1150
Cdd:PTZ00121 1804 FDNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2313-2407 8.92e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 8.92e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   2313 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2392
Cdd:smart00557    1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581634   2393 EHVPGSPFLVMIVDT 2407
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
2310-2400 1.08e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 94.28  E-value: 1.08e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  2310 PPDPSKVRVYGPGVEHGILSLfKSNFVVETRGAGaGQLTVRVRGPKGAFnVEMQREKKNERTIHCKYEPKEPGDYQVEVK 2389
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGK-PAEFTVDTRDAG-GEGEVEVTGPDGSP-VPVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|.
gi 922581634  2390 WHGEHVPGSPF 2400
Cdd:pfam00630   78 FNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2219-2310 6.85e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.90  E-value: 6.85e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   2219 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2297
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581634   2298 VKGSPFVVHVSLP 2310
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
15-107 1.43e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.13  E-value: 1.43e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634     15 ASSVSVYGENLRSASVGKTASFMVHAIGAEAKDISAHVTVPSGGKFPAKVVTLDDVTFQIEWTPKEPGEHSVDVMLADQR 94
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581634     95 VPDAPFACNVGAP 107
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2124-2213 1.13e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.13e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   2124 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2202
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|.
gi 922581634   2203 VKGSPFAVSAD 2213
Cdd:smart00557   81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1389-1472 5.52e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.81  E-value: 5.52e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1389 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVCEGR---VPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1463
Cdd:smart00557    1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                    ....*....
gi 922581634   1464 VPGSPFLCQ 1472
Cdd:smart00557   81 IPGSPFTVK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1143-1236 1.30e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 1.30e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1143 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1221
Cdd:smart00557    1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581634   1222 EVLKNSPFEVNIVDA 1236
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
304-388 7.64e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 80.73  E-value: 7.64e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    304 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 380
Cdd:smart00557    5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*...
gi 922581634    381 PIKVEILP 388
Cdd:smart00557   85 PFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
13-100 3.81e-17

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 78.48  E-value: 3.81e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    13 ADASSVSVYGENLRSASVGKTASFMVHAIGAEAkDISAHVTVPSGGKFPAKVVTLDDVTFQIEWTPKEPGEHSVDVMLAD 92
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGG-EGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*...
gi 922581634    93 QRVPDAPF 100
Cdd:pfam00630   81 QHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1300-1389 4.81e-17

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 78.41  E-value: 4.81e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1300 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1375
Cdd:smart00557    1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 922581634   1376 PVTGSPFTCRAYDP 1389
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1579-1658 1.40e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.40e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1579 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1657
Cdd:smart00557   13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92

                    .
gi 922581634   1658 A 1658
Cdd:smart00557   93 A 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
212-297 1.49e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.49e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    212 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 291
Cdd:smart00557    3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                    ....*.
gi 922581634    292 GSPLSV 297
Cdd:smart00557   83 GSPFTV 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1723-1804 1.74e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.49  E-value: 1.74e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1723 LNSAQIGQKKGFTIDNINK-SSDCNVIITDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPGSPFKTEV 1801
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ...
gi 922581634   1802 IDP 1804
Cdd:smart00557   91 GPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1723-1798 2.45e-16

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 76.17  E-value: 2.45e-16
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581634  1723 LNSAQIGQKKGFTIDNINKSSDCNVIITDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPGSPFK 1798
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1900-1987 1.08e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.56  E-value: 1.08e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1900 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 1978
Cdd:smart00557    6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581634   1979 PFTVNVVDP 1987
Cdd:smart00557   85 PFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1486-1569 1.03e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 71.48  E-value: 1.03e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1486 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1564
Cdd:smart00557   11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88

                    ....*
gi 922581634   1565 KAYDA 1569
Cdd:smart00557   89 KVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
119-197 1.90e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 70.71  E-value: 1.90e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    119 IQPSKLHTDHSFEIDASAAGSGNLEIMI---NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPV 195
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ..
gi 922581634    196 ED 197
Cdd:smart00557   91 GP 92
Filamin pfam00630
Filamin/ABP280 repeat;
1900-1981 4.15e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 69.63  E-value: 4.15e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1900 VYGAAVDQSiKIGEPASLIFDPKKTNGGLKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGSP 1979
Cdd:pfam00630    9 ASGPGLEPG-VVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581634  1980 FT 1981
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1566-1650 8.87e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.85  E-value: 8.87e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1566 AYDARKTVLVPPA--NAVVGKPATFVIDAARSGAGNMEIIVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNG 1643
Cdd:pfam00630    1 AADASKVKASGPGlePGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*..
gi 922581634  1644 ISVPGSP 1650
Cdd:pfam00630   81 QHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
2124-2208 1.24e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.47  E-value: 1.24e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  2124 SRIMVRGDGLHRAVLKEHNEFIIDGSDinKEGRITATLLGSK-ADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2202
Cdd:pfam00630    5 SKVKASGPGLEPGVVGKPAEFTVDTRD--AGGEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQH 82

                   ....*.
gi 922581634  2203 VKGSPF 2208
Cdd:pfam00630   83 IPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1386-1469 2.22e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 67.70  E-value: 2.22e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1386 AYDPAKIKVG--AIPKGLLDKPVYFTVDASEAGvGNLEVAVCE---GRVPSMAHALGHHKYDISFVPKEDVDHTITVRFN 1460
Cdd:pfam00630    1 AADASKVKASgpGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGpdgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*....
gi 922581634  1461 NEPVPGSPF 1469
Cdd:pfam00630   80 GQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
304-383 2.19e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 65.00  E-value: 2.19e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   304 KVRLEPLGGGVPKQPVQFYVDAVEA-GKGQLEISVNQGK-VPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGCP 381
Cdd:pfam00630    8 KASGPGLEPGVVGKPAEFTVDTRDAgGEGEVEVTGPDGSpVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581634   382 IK 383
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
213-294 7.13e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 63.46  E-value: 7.13e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   213 SELSGPGLVRAPVNRTAQFDITGEGlELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVDG 292
Cdd:pfam00630    7 VKASGPGLEPGVVGKPAEFTVDTRD-AGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85

                   ..
gi 922581634   293 SP 294
Cdd:pfam00630   86 SP 87
Filamin pfam00630
Filamin/ABP280 repeat;
1140-1230 1.42e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 62.69  E-value: 1.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1140 VYDASEIIV-GEIPNQSNLNDTVEFTVDAGRAGfGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNIT 1218
Cdd:pfam00630    1 AADASKVKAsGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGT--YTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|..
gi 922581634  1219 FNKEVLKNSPFE 1230
Cdd:pfam00630   78 FNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1313-1383 8.99e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 8.99e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581634  1313 RVGQPSSLVVEVSGHD-QLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGVPVTGSPFT 1383
Cdd:pfam00630   18 VVGKPAEFTVDTRDAGgEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1486-1563 1.94e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 59.22  E-value: 1.94e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581634  1486 LERIPVDEETEIQILTDEIDSAPEARVRDPQGNDLPVNVTrSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFT 1563
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVT-DNGDGT-YTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1821-1894 2.94e-10

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 58.77  E-value: 2.94e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581634   1821 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 1894
Cdd:smart00557   19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
2229-2304 3.63e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 58.45  E-value: 3.63e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 922581634  2229 LKIGIINENIKTLIDTRRAGsGQLSALCMGPN-KPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEHVKGSPFV 2304
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1801-1887 7.54e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 57.68  E-value: 7.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1801 VIDPKNVEIRGLS-DQVLLRHATTINVDRRNAGnGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVA 1879
Cdd:pfam00630    1 AADASKVKASGPGlEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*...
gi 922581634  1880 GFQIPGYP 1887
Cdd:pfam00630   80 GQHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
119-192 1.89e-09

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 56.53  E-value: 1.89e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581634   119 IQPSKLHTDHSFEIDAS-AAGSGNLEIMI-NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWK 192
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRdAGGEGEVEVTGpDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2006-2082 2.63e-09

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 56.07  E-value: 2.63e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581634   2006 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 2082
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
1984-2074 1.96e-08

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 53.83  E-value: 1.96e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1984 VVDPTKVIVNDLDMDRDgtlllRLGHSNSFDVDATAAGpGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKY 2063
Cdd:pfam00630    1 AADASKVKASGPGLEPG-----VVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVP--VEVTDNGDGTYTVSYTPTEPGDY 72
                           90
                   ....*....|.
gi 922581634  2064 SIYLYWNELPV 2074
Cdd:pfam00630   73 TVSVKFNGQHI 83
PTZ00121 PTZ00121
MAEBL; Provisional
728-1150 2.35e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 2.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  728 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 807
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  808 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 884
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  885 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV--------- 955
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakka 1670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  956 -----------KSEDDKILAKHGFTRKPEPSIEIqepvtEQIRDDVVETAIAPEvPLRPVEELPHSPAPSSRSTPATTPK 1024
Cdd:PTZ00121 1671 eedkkkaeeakKAEEDEKKAAEALKKEAEEAKKA-----EELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKK 1744
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634 1025 LSAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKS 1104
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDI 1803
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 922581634 1105 SSKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1150
Cdd:PTZ00121 1804 FDNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1056-1143 4.20e-05

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 44.13  E-value: 4.20e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1056 GKEVEVKLEGIKLGkEDQLRVVVLPPANKaipganggpptEVDTKVK-KSSSKYEISFKPTEVGTHKVFAYVNDMQHPLS 1134
Cdd:smart00557   17 GEPAEFTVDTRDAG-GGELEVEVTGPSGK-----------KVPVEVKdNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581634   1135 PFAVRVYDA 1143
Cdd:smart00557   85 PFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1086-1136 5.06e-04

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 41.12  E-value: 5.06e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 922581634  1086 IPGANGGP-PTEVdtkVKKSSSKYEISFKPTEVGTHKVFAYVNDMQHPLSPF 1136
Cdd:pfam00630   40 VTGPDGSPvPVEV---TDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2313-2407 8.92e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 8.92e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   2313 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2392
Cdd:smart00557    1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581634   2393 EHVPGSPFLVMIVDT 2407
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
2310-2400 1.08e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 94.28  E-value: 1.08e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  2310 PPDPSKVRVYGPGVEHGILSLfKSNFVVETRGAGaGQLTVRVRGPKGAFnVEMQREKKNERTIHCKYEPKEPGDYQVEVK 2389
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGK-PAEFTVDTRDAG-GEGEVEVTGPDGSP-VPVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|.
gi 922581634  2390 WHGEHVPGSPF 2400
Cdd:pfam00630   78 FNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2219-2310 6.85e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.90  E-value: 6.85e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   2219 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2297
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581634   2298 VKGSPFVVHVSLP 2310
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
15-107 1.43e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.13  E-value: 1.43e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634     15 ASSVSVYGENLRSASVGKTASFMVHAIGAEAKDISAHVTVPSGGKFPAKVVTLDDVTFQIEWTPKEPGEHSVDVMLADQR 94
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581634     95 VPDAPFACNVGAP 107
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2124-2213 1.13e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.13e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   2124 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2202
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|.
gi 922581634   2203 VKGSPFAVSAD 2213
Cdd:smart00557   81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1389-1472 5.52e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.81  E-value: 5.52e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1389 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVCEGR---VPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1463
Cdd:smart00557    1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                    ....*....
gi 922581634   1464 VPGSPFLCQ 1472
Cdd:smart00557   81 IPGSPFTVK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1143-1236 1.30e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 1.30e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1143 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1221
Cdd:smart00557    1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581634   1222 EVLKNSPFEVNIVDA 1236
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
304-388 7.64e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 80.73  E-value: 7.64e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    304 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 380
Cdd:smart00557    5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*...
gi 922581634    381 PIKVEILP 388
Cdd:smart00557   85 PFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
13-100 3.81e-17

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 78.48  E-value: 3.81e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    13 ADASSVSVYGENLRSASVGKTASFMVHAIGAEAkDISAHVTVPSGGKFPAKVVTLDDVTFQIEWTPKEPGEHSVDVMLAD 92
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGG-EGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*...
gi 922581634    93 QRVPDAPF 100
Cdd:pfam00630   81 QHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1300-1389 4.81e-17

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 78.41  E-value: 4.81e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1300 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1375
Cdd:smart00557    1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 922581634   1376 PVTGSPFTCRAYDP 1389
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1579-1658 1.40e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.40e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1579 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1657
Cdd:smart00557   13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92

                    .
gi 922581634   1658 A 1658
Cdd:smart00557   93 A 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
212-297 1.49e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.49e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    212 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 291
Cdd:smart00557    3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                    ....*.
gi 922581634    292 GSPLSV 297
Cdd:smart00557   83 GSPFTV 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1723-1804 1.74e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.49  E-value: 1.74e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1723 LNSAQIGQKKGFTIDNINK-SSDCNVIITDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPGSPFKTEV 1801
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ...
gi 922581634   1802 IDP 1804
Cdd:smart00557   91 GPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1723-1798 2.45e-16

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 76.17  E-value: 2.45e-16
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581634  1723 LNSAQIGQKKGFTIDNINKSSDCNVIITDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPGSPFK 1798
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1900-1987 1.08e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.56  E-value: 1.08e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1900 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 1978
Cdd:smart00557    6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581634   1979 PFTVNVVDP 1987
Cdd:smart00557   85 PFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1486-1569 1.03e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 71.48  E-value: 1.03e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1486 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1564
Cdd:smart00557   11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88

                    ....*
gi 922581634   1565 KAYDA 1569
Cdd:smart00557   89 KVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
119-197 1.90e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 70.71  E-value: 1.90e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634    119 IQPSKLHTDHSFEIDASAAGSGNLEIMI---NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPV 195
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ..
gi 922581634    196 ED 197
Cdd:smart00557   91 GP 92
Filamin pfam00630
Filamin/ABP280 repeat;
1900-1981 4.15e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 69.63  E-value: 4.15e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1900 VYGAAVDQSiKIGEPASLIFDPKKTNGGLKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGSP 1979
Cdd:pfam00630    9 ASGPGLEPG-VVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581634  1980 FT 1981
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1566-1650 8.87e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.85  E-value: 8.87e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1566 AYDARKTVLVPPA--NAVVGKPATFVIDAARSGAGNMEIIVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNG 1643
Cdd:pfam00630    1 AADASKVKASGPGlePGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*..
gi 922581634  1644 ISVPGSP 1650
Cdd:pfam00630   81 QHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
2124-2208 1.24e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.47  E-value: 1.24e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  2124 SRIMVRGDGLHRAVLKEHNEFIIDGSDinKEGRITATLLGSK-ADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2202
Cdd:pfam00630    5 SKVKASGPGLEPGVVGKPAEFTVDTRD--AGGEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQH 82

                   ....*.
gi 922581634  2203 VKGSPF 2208
Cdd:pfam00630   83 IPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1386-1469 2.22e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 67.70  E-value: 2.22e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1386 AYDPAKIKVG--AIPKGLLDKPVYFTVDASEAGvGNLEVAVCE---GRVPSMAHALGHHKYDISFVPKEDVDHTITVRFN 1460
Cdd:pfam00630    1 AADASKVKASgpGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGpdgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*....
gi 922581634  1461 NEPVPGSPF 1469
Cdd:pfam00630   80 GQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
304-383 2.19e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 65.00  E-value: 2.19e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   304 KVRLEPLGGGVPKQPVQFYVDAVEA-GKGQLEISVNQGK-VPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGCP 381
Cdd:pfam00630    8 KASGPGLEPGVVGKPAEFTVDTRDAgGEGEVEVTGPDGSpVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581634   382 IK 383
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
213-294 7.13e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 63.46  E-value: 7.13e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   213 SELSGPGLVRAPVNRTAQFDITGEGlELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVDG 292
Cdd:pfam00630    7 VKASGPGLEPGVVGKPAEFTVDTRD-AGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85

                   ..
gi 922581634   293 SP 294
Cdd:pfam00630   86 SP 87
Filamin pfam00630
Filamin/ABP280 repeat;
1140-1230 1.42e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 62.69  E-value: 1.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1140 VYDASEIIV-GEIPNQSNLNDTVEFTVDAGRAGfGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNIT 1218
Cdd:pfam00630    1 AADASKVKAsGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGT--YTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|..
gi 922581634  1219 FNKEVLKNSPFE 1230
Cdd:pfam00630   78 FNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1313-1383 8.99e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 8.99e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581634  1313 RVGQPSSLVVEVSGHD-QLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGVPVTGSPFT 1383
Cdd:pfam00630   18 VVGKPAEFTVDTRDAGgEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1486-1563 1.94e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 59.22  E-value: 1.94e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581634  1486 LERIPVDEETEIQILTDEIDSAPEARVRDPQGNDLPVNVTrSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFT 1563
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVT-DNGDGT-YTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1821-1894 2.94e-10

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 58.77  E-value: 2.94e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581634   1821 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 1894
Cdd:smart00557   19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
2229-2304 3.63e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 58.45  E-value: 3.63e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 922581634  2229 LKIGIINENIKTLIDTRRAGsGQLSALCMGPN-KPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEHVKGSPFV 2304
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1801-1887 7.54e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 57.68  E-value: 7.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1801 VIDPKNVEIRGLS-DQVLLRHATTINVDRRNAGnGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVA 1879
Cdd:pfam00630    1 AADASKVKASGPGlEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*...
gi 922581634  1880 GFQIPGYP 1887
Cdd:pfam00630   80 GQHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
119-192 1.89e-09

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 56.53  E-value: 1.89e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581634   119 IQPSKLHTDHSFEIDAS-AAGSGNLEIMI-NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWK 192
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRdAGGEGEVEVTGpDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2006-2082 2.63e-09

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 56.07  E-value: 2.63e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581634   2006 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 2082
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
1984-2074 1.96e-08

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 53.83  E-value: 1.96e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  1984 VVDPTKVIVNDLDMDRDgtlllRLGHSNSFDVDATAAGpGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKY 2063
Cdd:pfam00630    1 AADASKVKASGPGLEPG-----VVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVP--VEVTDNGDGTYTVSYTPTEPGDY 72
                           90
                   ....*....|.
gi 922581634  2064 SIYLYWNELPV 2074
Cdd:pfam00630   73 TVSVKFNGQHI 83
PTZ00121 PTZ00121
MAEBL; Provisional
728-1150 2.35e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 2.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  728 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 807
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  808 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 884
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  885 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV--------- 955
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakka 1670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634  956 -----------KSEDDKILAKHGFTRKPEPSIEIqepvtEQIRDDVVETAIAPEvPLRPVEELPHSPAPSSRSTPATTPK 1024
Cdd:PTZ00121 1671 eedkkkaeeakKAEEDEKKAAEALKKEAEEAKKA-----EELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKK 1744
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634 1025 LSAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKS 1104
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDI 1803
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 922581634 1105 SSKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1150
Cdd:PTZ00121 1804 FDNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1056-1143 4.20e-05

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 44.13  E-value: 4.20e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581634   1056 GKEVEVKLEGIKLGkEDQLRVVVLPPANKaipganggpptEVDTKVK-KSSSKYEISFKPTEVGTHKVFAYVNDMQHPLS 1134
Cdd:smart00557   17 GEPAEFTVDTRDAG-GGELEVEVTGPSGK-----------KVPVEVKdNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581634   1135 PFAVRVYDA 1143
Cdd:smart00557   85 PFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1086-1136 5.06e-04

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 41.12  E-value: 5.06e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 922581634  1086 IPGANGGP-PTEVdtkVKKSSSKYEISFKPTEVGTHKVFAYVNDMQHPLSPF 1136
Cdd:pfam00630   40 VTGPDGSPvPVEV---TDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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