|
Name |
Accession |
Description |
Interval |
E-value |
| FReD |
cd00087 |
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
1589-1798 |
4.05e-111 |
|
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.
:
Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 351.54 E-value: 4.05e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1589 KHPKDCSQALLNGDTTSGLYTIYLRGDeSQPLQVYCDMTTDGGGWIVFVRRQSGKVEFFRNWKNYTAGFGDLNDEFWLGL 1668
Cdd:cd00087 1 PLPRDCSEVLQRGGRTSGVYTIQPPGS-NEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1669 SNLHKITSFGQYELRVDLRD-KGESAYAQYDKFSISEPRARYKVHVGGYSGTAGDSMTYHHGRPFSTYDNDNDIAVTNCA 1747
Cdd:cd00087 80 EKIHLLTSQGPYELRIDLEDwEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 922304343 1748 LSYKGAFWYKNCHRVNIMGRYG----DNSHSKGVNWFHWKGHEHSVEFAEMKIRP 1798
Cdd:cd00087 160 ESYSGGWWYNSCHASNLNGRYYsgghRNEYDNGINWATWKGSTYSLKFTEMKIRP 214
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1333-1568 |
2.46e-18 |
|
Fibronectin type 3 domain [General function prediction only];
:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 91.22 E-value: 2.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1333 DTSATVHWTMPHTRVDNYRVIYVPIQGGSPLTLRVDGGESQ---AMLSNLTPGVTYQVTVIAVKGLEESEPGSE----RV 1405
Cdd:COG3401 150 VDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTtlvDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTP 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1406 TTALDKPRGLTAVNISDTEALLLWQPSIAT-VDGYVITYSADSVAPVMERVSGNTVEFEMSSLTPATLYTVKVYAFrDTA 1484
Cdd:COG3401 230 TTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAV-DAA 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1485 --KSAATST-DFTTDV---DAPQNLAASNIQTETAMLTWKPPR-ADISGY-ILSFESADGVVKEVVLSPTATFYSMSQLT 1556
Cdd:COG3401 309 gnESAPSNVvSVTTDLtppAAPSGLTATAVGSSSITLSWTASSdADVTGYnVYRSTSGGGTYTKIAETVTTTSYTDTGLT 388
|
250
....*....|..
gi 922304343 1557 ASTEYTVKLQAI 1568
Cdd:COG3401 389 PGTTYYYKVTAV 400
|
|
| FN3 super family |
cl27307 |
Fibronectin type 3 domain [General function prediction only]; |
853-1296 |
4.88e-12 |
|
Fibronectin type 3 domain [General function prediction only];
The actual alignment was detected with superfamily member COG3401:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.80 E-value: 4.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 853 NTRGPPASKNVVTMIDAPSQVDV--RDVTDTTALVTWLQPVAQVDGISVSYGPNTDSSDRNTIELSSIETQYHLAELSPD 930
Cdd:COG3401 123 GTATTATAVAGGAATAGTYALGAglYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPG 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 931 TEYEVSLMARRGEMSSFPIYE----TFTTDLDSPKHLKAIEQTDESITLEWR-NSRANVLNYRVKYGPLSGGEHGELVFP 1005
Cdd:COG3401 203 TTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKVATV 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1006 SglqdTTQAKITGLRPGTEYGMGVTSI-KEERESLPATT-NAVTDLDPPK---DLQVSETTETTLALVWRRPVAKIDTYS 1080
Cdd:COG3401 283 T----TTSYTDTGLTNGTTYYYRVTAVdAAGNESAPSNVvSVTTDLTPPAapsGLTATAVGSSSITLSWTASSDADVTGY 358
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1081 LVF--IPADGDKTELKIPGAANTYILTGLNPGMLHTITLTA-----------ERGRKMSAPATLSASTDEEKPQVGNITI 1147
Cdd:COG3401 359 NVYrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdaagnesapsEEVSATTASAASGESLTASVDAVPLTDV 438
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1148 SDVSWDSFSMSWDLDRGEVEGflievsdpdGLSDGQNHTLSGQEFSLAVTDLSPSTFYRVTLYGlYKGELLDPVFAEAIT 1227
Cdd:COG3401 439 AGATAAASAASNPGVSAAVLA---------DGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTT-GSLVGGSGASSVTNS 508
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 922304343 1228 EAEPEVEHITVSDITPHSFKVTWTAPEAVFDSFALKVL--DSSGLGRPHQISVSGDKRTEAVTGLNEDTDY 1296
Cdd:COG3401 509 VSVIGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLitDLVSLTTSASSSVSGAGLGSGNLYLITTLGG 579
|
|
| FN3 super family |
cl27307 |
Fibronectin type 3 domain [General function prediction only]; |
689-908 |
7.82e-12 |
|
Fibronectin type 3 domain [General function prediction only];
The actual alignment was detected with superfamily member COG3401:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.42 E-value: 7.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 689 SPPRDLTVTEVDPETVDVAW--VNEMLVTEYLITYVPTAPGGLEmemRVSGEKKTA-TIRELEPGIEYLISVFAV----L 761
Cdd:COG3401 234 SAPTGLTATADTPGSVTLSWdpVTESDATGYRVYRSNSGDGPFT---KVATVTTTSyTDTGLTNGTTYYYRVTAVdaagN 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 762 NSKMSVPVSARIATHLPE-PEGLKFKSVKETSVEVEWDP-LNIPFDGWNlIFRNTKEEDGEILNSLAPPETTFEQSGLGP 839
Cdd:COG3401 311 ESAPSNVVSVTTDLTPPAaPSGLTATAVGSSSITLSWTAsSDADVTGYN-VYRSTSGGGTYTKIAETVTTTSYTDTGLTP 389
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922304343 840 GQEYEVKLEVVKNNTRGPPASKNVVTMidaPSQVDVRDVTDTTALVTWLQPVAQVDGISVSYGPNTDSS 908
Cdd:COG3401 390 GTTYYYKVTAVDAAGNESAPSEEVSAT---TASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSA 455
|
|
| PRK10767 super family |
cl35946 |
chaperone protein DnaJ; Provisional |
471-544 |
3.78e-05 |
|
chaperone protein DnaJ; Provisional
The actual alignment was detected with superfamily member PRK10767:
Pssm-ID: 236757 [Multi-domain] Cd Length: 371 Bit Score: 48.22 E-value: 3.78e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 922304343 471 KTCPHhCHGHGQcVDGKcichKGFAgedcSI-KTCPnHCHGQGQCIDGKCichdgfagedcsiktcpNHCHGRGR 544
Cdd:PRK10767 160 KTCPT-CHGAGQ-VRMQ----QGFF----TVqQTCP-TCHGRGKIIKDPC-----------------KKCHGQGR 206
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
318-345 |
2.42e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 39.97 E-value: 2.42e-04
10 20
....*....|....*....|....*...
gi 922304343 318 CPQNCNHHGRCVNGQCICNIGYSGEDCS 345
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
380-407 |
2.42e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 39.97 E-value: 2.42e-04
10 20
....*....|....*....|....*...
gi 922304343 380 CPDNCNGRGHCVNGECICGPGYEGDDCS 407
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
659-686 |
8.10e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 38.43 E-value: 8.10e-04
10 20
....*....|....*....|....*...
gi 922304343 659 CPADCNDQGQCLNGMCICDLGFTGDDCS 686
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
535-562 |
2.06e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 37.28 E-value: 2.06e-03
10 20
....*....|....*....|....*...
gi 922304343 535 CPNHCHGRGRCVDGKCICHDGFAGEDCN 562
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
597-623 |
2.25e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 37.28 E-value: 2.25e-03
10 20
....*....|....*....|....*..
gi 922304343 597 CPNDCHNRGRCVNGQCVCNIGFTGEDC 623
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
256-283 |
2.71e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 36.89 E-value: 2.71e-03
10 20
....*....|....*....|....*...
gi 922304343 256 CPSNCLGRGRCVDDECVCDEPWTGFDCS 283
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
628-655 |
2.74e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 36.89 E-value: 2.74e-03
10 20
....*....|....*....|....*...
gi 922304343 628 CPNNCLDRGFCEDGKCVCFEGYTGEDCS 655
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
566-593 |
4.31e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 36.51 E-value: 4.31e-03
10 20
....*....|....*....|....*...
gi 922304343 566 CPNDCHDHGECVDGKCICHAGFTGHDCS 593
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
225-252 |
6.77e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 35.74 E-value: 6.77e-03
10 20
....*....|....*....|....*...
gi 922304343 225 CPVDCGENGECIDGACICAEGFIGEDCS 252
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FReD |
cd00087 |
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
1589-1798 |
4.05e-111 |
|
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.
Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 351.54 E-value: 4.05e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1589 KHPKDCSQALLNGDTTSGLYTIYLRGDeSQPLQVYCDMTTDGGGWIVFVRRQSGKVEFFRNWKNYTAGFGDLNDEFWLGL 1668
Cdd:cd00087 1 PLPRDCSEVLQRGGRTSGVYTIQPPGS-NEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1669 SNLHKITSFGQYELRVDLRD-KGESAYAQYDKFSISEPRARYKVHVGGYSGTAGDSMTYHHGRPFSTYDNDNDIAVTNCA 1747
Cdd:cd00087 80 EKIHLLTSQGPYELRIDLEDwEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 922304343 1748 LSYKGAFWYKNCHRVNIMGRYG----DNSHSKGVNWFHWKGHEHSVEFAEMKIRP 1798
Cdd:cd00087 160 ESYSGGWWYNSCHASNLNGRYYsgghRNEYDNGINWATWKGSTYSLKFTEMKIRP 214
|
|
| FBG |
smart00186 |
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ... |
1590-1799 |
2.12e-108 |
|
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.
Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 343.88 E-value: 2.12e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1590 HPKDCSQALLNGDTTSGLYTIYLRGDeSQPLQVYCDMTTDGGGWIVFVRRQSGKVEFFRNWKNYTAGFGDLNDEFWLGLS 1669
Cdd:smart00186 1 LPRDCSDVLQNGGKTSGLYTIYPDGS-SRPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1670 NLHKITSFGQYELRVDLRD-KGESAYAQYDKFSISEPRARYKVHVGGYSGTAGD-SMTYHHGRPFSTYDNDNDIAVTNCA 1747
Cdd:smart00186 80 NIHLLTSQGKYELRIDLEDwEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 922304343 1748 LSYKGAFWYKNCHRVNIMGRYG-DNSHSKGVNWFHWKGHEHSVEFAEMKIRPA 1799
Cdd:smart00186 160 EEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRPL 212
|
|
| Fibrinogen_C |
pfam00147 |
Fibrinogen beta and gamma chains, C-terminal globular domain; |
1591-1798 |
7.03e-99 |
|
Fibrinogen beta and gamma chains, C-terminal globular domain;
Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 317.16 E-value: 7.03e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1591 PKDCSQALLNGDTTSGLYTIYLRGDeSQPLQVYCDMTTDGGGWIVFVRRQSGKVEFFRNWKNYTAGFGDL-NDEFWLGLS 1669
Cdd:pfam00147 2 GRDCSDVYNKGAKTSGLYTIRPDGA-TKPFEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLsPGEFWLGND 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1670 NLHKITSFGQYELRVDLRD-KGESAYAQYDKFSISEPRARYKVHVGGYSGTAGD-------SMTYHHGRPFSTYDNDNDI 1741
Cdd:pfam00147 81 KIHLLTKQGPYVLRIDLEDwNGETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDNDS 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1742 AVTNCALSYKGAFWYKNCHRVNIMGRY---GDNSHSKGVNWFHWKGHEHSVEFAEMKIRP 1798
Cdd:pfam00147 161 PDGNCALSYGGGWWYNNCHAANLNGVYyygGTYSKQNGIIWATWKGRWYSMKKAEMKIRP 220
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1333-1568 |
2.46e-18 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 91.22 E-value: 2.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1333 DTSATVHWTMPHTRVDNYRVIYVPIQGGSPLTLRVDGGESQ---AMLSNLTPGVTYQVTVIAVKGLEESEPGSE----RV 1405
Cdd:COG3401 150 VDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTtlvDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTP 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1406 TTALDKPRGLTAVNISDTEALLLWQPSIAT-VDGYVITYSADSVAPVMERVSGNTVEFEMSSLTPATLYTVKVYAFrDTA 1484
Cdd:COG3401 230 TTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAV-DAA 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1485 --KSAATST-DFTTDV---DAPQNLAASNIQTETAMLTWKPPR-ADISGY-ILSFESADGVVKEVVLSPTATFYSMSQLT 1556
Cdd:COG3401 309 gnESAPSNVvSVTTDLtppAAPSGLTATAVGSSSITLSWTASSdADVTGYnVYRSTSGGGTYTKIAETVTTTSYTDTGLT 388
|
250
....*....|..
gi 922304343 1557 ASTEYTVKLQAI 1568
Cdd:COG3401 389 PGTTYYYKVTAV 400
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1323-1400 |
1.11e-16 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 76.68 E-value: 1.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1323 PKGIRFSDVTDTSATVHWTMPHTR---VDNYRVIYVPIQGGSP-LTLRVDGGESQAMLSNLTPGVTYQVTVIAVKGLEES 1398
Cdd:pfam00041 3 PSNLTVTDVTSTSLTVSWTPPPDGngpITGYEVEYRPKNSGEPwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82
|
..
gi 922304343 1399 EP 1400
Cdd:pfam00041 83 PP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1321-1407 |
4.21e-15 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 72.53 E-value: 4.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1321 GTPKGIRFSDVTDTSATVHWTMP---HTRVDNYRVIYVPIQGGSPLTLRV-DGGESQAMLSNLTPGVTYQVTVIAVKGLE 1396
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPeddGGPITGYVVEYREKGSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 922304343 1397 ESEPG-SERVTT 1407
Cdd:cd00063 82 ESPPSeSVTVTT 93
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
853-1296 |
4.88e-12 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.80 E-value: 4.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 853 NTRGPPASKNVVTMIDAPSQVDV--RDVTDTTALVTWLQPVAQVDGISVSYGPNTDSSDRNTIELSSIETQYHLAELSPD 930
Cdd:COG3401 123 GTATTATAVAGGAATAGTYALGAglYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPG 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 931 TEYEVSLMARRGEMSSFPIYE----TFTTDLDSPKHLKAIEQTDESITLEWR-NSRANVLNYRVKYGPLSGGEHGELVFP 1005
Cdd:COG3401 203 TTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKVATV 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1006 SglqdTTQAKITGLRPGTEYGMGVTSI-KEERESLPATT-NAVTDLDPPK---DLQVSETTETTLALVWRRPVAKIDTYS 1080
Cdd:COG3401 283 T----TTSYTDTGLTNGTTYYYRVTAVdAAGNESAPSNVvSVTTDLTPPAapsGLTATAVGSSSITLSWTASSDADVTGY 358
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1081 LVF--IPADGDKTELKIPGAANTYILTGLNPGMLHTITLTA-----------ERGRKMSAPATLSASTDEEKPQVGNITI 1147
Cdd:COG3401 359 NVYrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdaagnesapsEEVSATTASAASGESLTASVDAVPLTDV 438
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1148 SDVSWDSFSMSWDLDRGEVEGflievsdpdGLSDGQNHTLSGQEFSLAVTDLSPSTFYRVTLYGlYKGELLDPVFAEAIT 1227
Cdd:COG3401 439 AGATAAASAASNPGVSAAVLA---------DGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTT-GSLVGGSGASSVTNS 508
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 922304343 1228 EAEPEVEHITVSDITPHSFKVTWTAPEAVFDSFALKVL--DSSGLGRPHQISVSGDKRTEAVTGLNEDTDY 1296
Cdd:COG3401 509 VSVIGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLitDLVSLTTSASSSVSGAGLGSGNLYLITTLGG 579
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
689-908 |
7.82e-12 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.42 E-value: 7.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 689 SPPRDLTVTEVDPETVDVAW--VNEMLVTEYLITYVPTAPGGLEmemRVSGEKKTA-TIRELEPGIEYLISVFAV----L 761
Cdd:COG3401 234 SAPTGLTATADTPGSVTLSWdpVTESDATGYRVYRSNSGDGPFT---KVATVTTTSyTDTGLTNGTTYYYRVTAVdaagN 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 762 NSKMSVPVSARIATHLPE-PEGLKFKSVKETSVEVEWDP-LNIPFDGWNlIFRNTKEEDGEILNSLAPPETTFEQSGLGP 839
Cdd:COG3401 311 ESAPSNVVSVTTDLTPPAaPSGLTATAVGSSSITLSWTAsSDADVTGYN-VYRSTSGGGTYTKIAETVTTTSYTDTGLTP 389
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922304343 840 GQEYEVKLEVVKNNTRGPPASKNVVTMidaPSQVDVRDVTDTTALVTWLQPVAQVDGISVSYGPNTDSS 908
Cdd:COG3401 390 GTTYYYKVTAVDAAGNESAPSEEVSAT---TASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSA 455
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
958-1047 |
1.48e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 62.13 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 958 DSPKHLKAIEQTDESITLEW---RNSRANVLNYRVKYGPLSGGEHGELVFPSGlqDTTQAKITGLRPGTEYGMGVTSIKE 1034
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWtppEDDGGPITGYVVEYREKGSGDWKEVEVTPG--SETSYTLTGLKPGTEYEFRVRAVNG 79
|
90
....*....|...
gi 922304343 1035 ERESLPATTNAVT 1047
Cdd:cd00063 80 GGESPPSESVTVT 92
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1140-1215 |
2.10e-11 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.66 E-value: 2.10e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922304343 1140 PQVGNITISDVSWDSFSMSW---DLDRGEVEGFLIEVSDPDGLSDGQNHTLSGQEFSLAVTDLSPSTFYRVTLYGLYKG 1215
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
778-858 |
2.21e-11 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.66 E-value: 2.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 778 PEPEGLKFKSVKETSVEVEWDP---LNIPFDGWNLIFRNTKEEDGEILNSLAPPETTFEQSGLGPGQEYEVKLEVVKNNT 854
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 922304343 855 RGPP 858
Cdd:pfam00041 81 EGPP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
780-865 |
4.67e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 60.97 E-value: 4.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 780 PEGLKFKSVKETSVEVEWDPL---NIPFDGWNLIFRNTKEEDGEILNSLAPPETTFEQSGLGPGQEYEVKLEVVKNNTRG 856
Cdd:cd00063 4 PTNLRVTDVTSTSVTLSWTPPeddGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGES 83
|
....*....
gi 922304343 857 PPASKNVVT 865
Cdd:cd00063 84 PPSESVTVT 92
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1321-1398 |
5.21e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 60.32 E-value: 5.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1321 GTPKGIRFSDVTDTSATVHWTMP-HTRVDNYRVIYVPI---QGGSPLTLRVDGGESQAMLSNLTPGVTYQVTVIAVKGLE 1396
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpDDGITGYIVGYRVEyreEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 922304343 1397 ES 1398
Cdd:smart00060 82 EG 83
|
|
| GGGWT_bact |
NF040941 |
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ... |
1594-1633 |
3.36e-09 |
|
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.
Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 54.11 E-value: 3.36e-09
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 922304343 1594 CSQALLNG-DTTSGLYTIYLRGDES-QPLQVYCDMTTDGGGW 1633
Cdd:NF040941 2 CWEILQAGpSAPSGVYWIDPDGMGGlAPFQVYCDMTTDGGGW 43
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1050-1123 |
7.08e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 54.54 E-value: 7.08e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922304343 1050 DPPKDLQVSETTETTLALVWRRP-----VAKIDTYSLVFIPADGDKTELKIPGAANTYILTGLNPGMLHTITLTAERGR 1123
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
689-760 |
1.32e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.77 E-value: 1.32e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922304343 689 SPPRDLTVTEVDPETVDVAW--VNEMLVTEYLITYVP--TAPGGLEMEMRVSGEKKTATIRELEPGIEYLISVFAV 760
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWepPPDDGITGYIVGYRVeyREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
|
|
| PRK10767 |
PRK10767 |
chaperone protein DnaJ; Provisional |
471-544 |
3.78e-05 |
|
chaperone protein DnaJ; Provisional
Pssm-ID: 236757 [Multi-domain] Cd Length: 371 Bit Score: 48.22 E-value: 3.78e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 922304343 471 KTCPHhCHGHGQcVDGKcichKGFAgedcSI-KTCPnHCHGQGQCIDGKCichdgfagedcsiktcpNHCHGRGR 544
Cdd:PRK10767 160 KTCPT-CHGAGQ-VRMQ----QGFF----TVqQTCP-TCHGRGKIIKDPC-----------------KKCHGQGR 206
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
318-345 |
2.42e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.97 E-value: 2.42e-04
10 20
....*....|....*....|....*...
gi 922304343 318 CPQNCNHHGRCVNGQCICNIGYSGEDCS 345
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
380-407 |
2.42e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.97 E-value: 2.42e-04
10 20
....*....|....*....|....*...
gi 922304343 380 CPDNCNGRGHCVNGECICGPGYEGDDCS 407
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
1412-1782 |
7.07e-04 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 43.99 E-value: 7.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1412 PRGLTAVNISDTEALLLWQPSIAT--VDGYVITYSADSVApvmerVSGNTVEFEMSSLTPATLYTVKVYAfRDTA-KSAA 1488
Cdd:COG3979 6 PTGLTASNVTSSSVSLSWDASTDNvgVTGYDVYRGGDQVA-----TVTGLTAWTVTGLTPGTEYTFTVGA-CDAAgNVSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1489 TSTDFTTDVDAPQNLAASNIQTETAMLTWKPPRADISGYILSFESADGVVKEVVLSPTATFYSMSQLTASTEYTVKLQAI 1568
Cdd:COG3979 80 ASGTSTAMFGGSSTTLGSAEGVADTSGNLAASGAFFGVTTPPTPSSTLVVDGTTTVNAAATANGGTGGSGGTTTIITTGV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1569 AGPkrSRVISTVFLTIGVLYKHPKDCSQALLNGDTTSGLYTIYLRGDESQPLQVYCDmTTDGGGWIVFVRRQSGKVEFFR 1648
Cdd:COG3979 160 EGG--GGSKTAQSLNAITAAGTAALNGGVVGGADEVLTCSAVKDDGSGGAGAGNTYW-ALNTLGVSDTPSGTTATGGTVG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1649 NWKNYTAGFGDLNDEFWLGLSNLHKITSFGQYELRVDLRDkgesAYAQYDKFSISEPRARYKVHVGGYSGTAGDSMTYHH 1728
Cdd:COG3979 237 ITSAYGAGVSGNAAVNVNAGFVVGNVGGAAGNTGTTSGTA----TSDAATNDVGDAAVTGLNDGAANGPTGGYGATGTTV 312
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 922304343 1729 GRPFSTYDNDNDIAVTNCALSYKGAFWYKNCHRVNIMGRYGDNSHSKGVNWFHW 1782
Cdd:COG3979 313 AGAAGVGGTKSGTGALGLSGAGGAGAAVSGTATGDDDAGADDSTAGVSGAGSTT 366
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
659-686 |
8.10e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.43 E-value: 8.10e-04
10 20
....*....|....*....|....*...
gi 922304343 659 CPADCNDQGQCLNGMCICDLGFTGDDCS 686
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
535-562 |
2.06e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.28 E-value: 2.06e-03
10 20
....*....|....*....|....*...
gi 922304343 535 CPNHCHGRGRCVDGKCICHDGFAGEDCN 562
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
597-623 |
2.25e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.28 E-value: 2.25e-03
10 20
....*....|....*....|....*..
gi 922304343 597 CPNDCHNRGRCVNGQCVCNIGFTGEDC 623
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
256-283 |
2.71e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.89 E-value: 2.71e-03
10 20
....*....|....*....|....*...
gi 922304343 256 CPSNCLGRGRCVDDECVCDEPWTGFDCS 283
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
628-655 |
2.74e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.89 E-value: 2.74e-03
10 20
....*....|....*....|....*...
gi 922304343 628 CPNNCLDRGFCEDGKCVCFEGYTGEDCS 655
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
473-500 |
3.08e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.89 E-value: 3.08e-03
10 20
....*....|....*....|....*...
gi 922304343 473 CPHHCHGHGQCVDGKCICHKGFAGEDCS 500
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
566-593 |
4.31e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.51 E-value: 4.31e-03
10 20
....*....|....*....|....*...
gi 922304343 566 CPNDCHDHGECVDGKCICHAGFTGHDCS 593
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
225-252 |
6.77e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 35.74 E-value: 6.77e-03
10 20
....*....|....*....|....*...
gi 922304343 225 CPVDCGENGECIDGACICAEGFIGEDCS 252
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FReD |
cd00087 |
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
1589-1798 |
4.05e-111 |
|
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.
Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 351.54 E-value: 4.05e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1589 KHPKDCSQALLNGDTTSGLYTIYLRGDeSQPLQVYCDMTTDGGGWIVFVRRQSGKVEFFRNWKNYTAGFGDLNDEFWLGL 1668
Cdd:cd00087 1 PLPRDCSEVLQRGGRTSGVYTIQPPGS-NEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1669 SNLHKITSFGQYELRVDLRD-KGESAYAQYDKFSISEPRARYKVHVGGYSGTAGDSMTYHHGRPFSTYDNDNDIAVTNCA 1747
Cdd:cd00087 80 EKIHLLTSQGPYELRIDLEDwEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 922304343 1748 LSYKGAFWYKNCHRVNIMGRYG----DNSHSKGVNWFHWKGHEHSVEFAEMKIRP 1798
Cdd:cd00087 160 ESYSGGWWYNSCHASNLNGRYYsgghRNEYDNGINWATWKGSTYSLKFTEMKIRP 214
|
|
| FBG |
smart00186 |
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ... |
1590-1799 |
2.12e-108 |
|
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.
Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 343.88 E-value: 2.12e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1590 HPKDCSQALLNGDTTSGLYTIYLRGDeSQPLQVYCDMTTDGGGWIVFVRRQSGKVEFFRNWKNYTAGFGDLNDEFWLGLS 1669
Cdd:smart00186 1 LPRDCSDVLQNGGKTSGLYTIYPDGS-SRPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1670 NLHKITSFGQYELRVDLRD-KGESAYAQYDKFSISEPRARYKVHVGGYSGTAGD-SMTYHHGRPFSTYDNDNDIAVTNCA 1747
Cdd:smart00186 80 NIHLLTSQGKYELRIDLEDwEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 922304343 1748 LSYKGAFWYKNCHRVNIMGRYG-DNSHSKGVNWFHWKGHEHSVEFAEMKIRPA 1799
Cdd:smart00186 160 EEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRPL 212
|
|
| Fibrinogen_C |
pfam00147 |
Fibrinogen beta and gamma chains, C-terminal globular domain; |
1591-1798 |
7.03e-99 |
|
Fibrinogen beta and gamma chains, C-terminal globular domain;
Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 317.16 E-value: 7.03e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1591 PKDCSQALLNGDTTSGLYTIYLRGDeSQPLQVYCDMTTDGGGWIVFVRRQSGKVEFFRNWKNYTAGFGDL-NDEFWLGLS 1669
Cdd:pfam00147 2 GRDCSDVYNKGAKTSGLYTIRPDGA-TKPFEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLsPGEFWLGND 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1670 NLHKITSFGQYELRVDLRD-KGESAYAQYDKFSISEPRARYKVHVGGYSGTAGD-------SMTYHHGRPFSTYDNDNDI 1741
Cdd:pfam00147 81 KIHLLTKQGPYVLRIDLEDwNGETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDNDS 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1742 AVTNCALSYKGAFWYKNCHRVNIMGRY---GDNSHSKGVNWFHWKGHEHSVEFAEMKIRP 1798
Cdd:pfam00147 161 PDGNCALSYGGGWWYNNCHAANLNGVYyygGTYSKQNGIIWATWKGRWYSMKKAEMKIRP 220
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1333-1568 |
2.46e-18 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 91.22 E-value: 2.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1333 DTSATVHWTMPHTRVDNYRVIYVPIQGGSPLTLRVDGGESQ---AMLSNLTPGVTYQVTVIAVKGLEESEPGSE----RV 1405
Cdd:COG3401 150 VDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTtlvDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTP 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1406 TTALDKPRGLTAVNISDTEALLLWQPSIAT-VDGYVITYSADSVAPVMERVSGNTVEFEMSSLTPATLYTVKVYAFrDTA 1484
Cdd:COG3401 230 TTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAV-DAA 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1485 --KSAATST-DFTTDV---DAPQNLAASNIQTETAMLTWKPPR-ADISGY-ILSFESADGVVKEVVLSPTATFYSMSQLT 1556
Cdd:COG3401 309 gnESAPSNVvSVTTDLtppAAPSGLTATAVGSSSITLSWTASSdADVTGYnVYRSTSGGGTYTKIAETVTTTSYTDTGLT 388
|
250
....*....|..
gi 922304343 1557 ASTEYTVKLQAI 1568
Cdd:COG3401 389 PGTTYYYKVTAV 400
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1323-1400 |
1.11e-16 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 76.68 E-value: 1.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1323 PKGIRFSDVTDTSATVHWTMPHTR---VDNYRVIYVPIQGGSP-LTLRVDGGESQAMLSNLTPGVTYQVTVIAVKGLEES 1398
Cdd:pfam00041 3 PSNLTVTDVTSTSLTVSWTPPPDGngpITGYEVEYRPKNSGEPwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82
|
..
gi 922304343 1399 EP 1400
Cdd:pfam00041 83 PP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1321-1407 |
4.21e-15 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 72.53 E-value: 4.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1321 GTPKGIRFSDVTDTSATVHWTMP---HTRVDNYRVIYVPIQGGSPLTLRV-DGGESQAMLSNLTPGVTYQVTVIAVKGLE 1396
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPeddGGPITGYVVEYREKGSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 922304343 1397 ESEPG-SERVTT 1407
Cdd:cd00063 82 ESPPSeSVTVTT 93
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1313-1578 |
1.94e-14 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 78.51 E-value: 1.94e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1313 FTVARTGLGTPKGIRFSDVTDTSATVHWTmPHT--RVDNYRvIYVPIQGGSPLTLRVDGGESQAMLSNLTPGVTYQVTVI 1390
Cdd:COG3401 226 VTTPTTPPSAPTGLTATADTPGSVTLSWD-PVTesDATGYR-VYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVT 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1391 AV-KGLEESEPgSERVTTALDK-----PRGLTAVNISDTEALLLWQPS-IATVDGYVITYSADSVAPVmERV--SGNTVE 1461
Cdd:COG3401 304 AVdAAGNESAP-SNVVSVTTDLtppaaPSGLTATAVGSSSITLSWTASsDADVTGYNVYRSTSGGGTY-TKIaeTVTTTS 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1462 FEMSSLTPATLYTVKVYAFRDT-AKSAATSTDFTTDVDAPQNL---AASNIQTETAMLTWKPPRADISGYILSFESADGV 1537
Cdd:COG3401 382 YTDTGLTPGTTYYYKVTAVDAAgNESAPSEEVSATTASAASGEsltASVDAVPLTDVAGATAAASAASNPGVSAAVLADG 461
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 922304343 1538 VKEVVLSP--TATFYSMSQLTASTEYTVKLQAIAGPKRSRVIS 1578
Cdd:COG3401 462 GDTGNAVPftTTSSTVTATTTDTTTANLSVTTGSLVGGSGASS 504
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1498-1570 |
4.72e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.59 E-value: 4.72e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922304343 1498 DAPQNLAASNIQTETAMLTWKPPR---ADISGYILSFESADG--VVKEVVLSPTATFYSMSQLTASTEYTVKLQAIAG 1570
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
853-1296 |
4.88e-12 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.80 E-value: 4.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 853 NTRGPPASKNVVTMIDAPSQVDV--RDVTDTTALVTWLQPVAQVDGISVSYGPNTDSSDRNTIELSSIETQYHLAELSPD 930
Cdd:COG3401 123 GTATTATAVAGGAATAGTYALGAglYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPG 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 931 TEYEVSLMARRGEMSSFPIYE----TFTTDLDSPKHLKAIEQTDESITLEWR-NSRANVLNYRVKYGPLSGGEHGELVFP 1005
Cdd:COG3401 203 TTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKVATV 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1006 SglqdTTQAKITGLRPGTEYGMGVTSI-KEERESLPATT-NAVTDLDPPK---DLQVSETTETTLALVWRRPVAKIDTYS 1080
Cdd:COG3401 283 T----TTSYTDTGLTNGTTYYYRVTAVdAAGNESAPSNVvSVTTDLTPPAapsGLTATAVGSSSITLSWTASSDADVTGY 358
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1081 LVF--IPADGDKTELKIPGAANTYILTGLNPGMLHTITLTA-----------ERGRKMSAPATLSASTDEEKPQVGNITI 1147
Cdd:COG3401 359 NVYrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdaagnesapsEEVSATTASAASGESLTASVDAVPLTDV 438
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1148 SDVSWDSFSMSWDLDRGEVEGflievsdpdGLSDGQNHTLSGQEFSLAVTDLSPSTFYRVTLYGlYKGELLDPVFAEAIT 1227
Cdd:COG3401 439 AGATAAASAASNPGVSAAVLA---------DGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTT-GSLVGGSGASSVTNS 508
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 922304343 1228 EAEPEVEHITVSDITPHSFKVTWTAPEAVFDSFALKVL--DSSGLGRPHQISVSGDKRTEAVTGLNEDTDY 1296
Cdd:COG3401 509 VSVIGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLitDLVSLTTSASSSVSGAGLGSGNLYLITTLGG 579
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
689-908 |
7.82e-12 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.42 E-value: 7.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 689 SPPRDLTVTEVDPETVDVAW--VNEMLVTEYLITYVPTAPGGLEmemRVSGEKKTA-TIRELEPGIEYLISVFAV----L 761
Cdd:COG3401 234 SAPTGLTATADTPGSVTLSWdpVTESDATGYRVYRSNSGDGPFT---KVATVTTTSyTDTGLTNGTTYYYRVTAVdaagN 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 762 NSKMSVPVSARIATHLPE-PEGLKFKSVKETSVEVEWDP-LNIPFDGWNlIFRNTKEEDGEILNSLAPPETTFEQSGLGP 839
Cdd:COG3401 311 ESAPSNVVSVTTDLTPPAaPSGLTATAVGSSSITLSWTAsSDADVTGYN-VYRSTSGGGTYTKIAETVTTTSYTDTGLTP 389
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922304343 840 GQEYEVKLEVVKNNTRGPPASKNVVTMidaPSQVDVRDVTDTTALVTWLQPVAQVDGISVSYGPNTDSS 908
Cdd:COG3401 390 GTTYYYKVTAVDAAGNESAPSEEVSAT---TASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSA 455
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
958-1047 |
1.48e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 62.13 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 958 DSPKHLKAIEQTDESITLEW---RNSRANVLNYRVKYGPLSGGEHGELVFPSGlqDTTQAKITGLRPGTEYGMGVTSIKE 1034
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWtppEDDGGPITGYVVEYREKGSGDWKEVEVTPG--SETSYTLTGLKPGTEYEFRVRAVNG 79
|
90
....*....|...
gi 922304343 1035 ERESLPATTNAVT 1047
Cdd:cd00063 80 GGESPPSESVTVT 92
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1410-1482 |
1.54e-11 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.05 E-value: 1.54e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922304343 1410 DKPRGLTAVNISDTEALLLWQPS---IATVDGYVITYSA--DSVAPVMERVSGNTVEFEMSSLTPATLYTVKVYAFRD 1482
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPknSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1140-1215 |
2.10e-11 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.66 E-value: 2.10e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922304343 1140 PQVGNITISDVSWDSFSMSW---DLDRGEVEGFLIEVSDPDGLSDGQNHTLSGQEFSLAVTDLSPSTFYRVTLYGLYKG 1215
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
778-858 |
2.21e-11 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.66 E-value: 2.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 778 PEPEGLKFKSVKETSVEVEWDP---LNIPFDGWNLIFRNTKEEDGEILNSLAPPETTFEQSGLGPGQEYEVKLEVVKNNT 854
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 922304343 855 RGPP 858
Cdd:pfam00041 81 EGPP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
780-865 |
4.67e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 60.97 E-value: 4.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 780 PEGLKFKSVKETSVEVEWDPL---NIPFDGWNLIFRNTKEEDGEILNSLAPPETTFEQSGLGPGQEYEVKLEVVKNNTRG 856
Cdd:cd00063 4 PTNLRVTDVTSTSVTLSWTPPeddGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGES 83
|
....*....
gi 922304343 857 PPASKNVVT 865
Cdd:cd00063 84 PPSESVTVT 92
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1321-1398 |
5.21e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 60.32 E-value: 5.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1321 GTPKGIRFSDVTDTSATVHWTMP-HTRVDNYRVIYVPI---QGGSPLTLRVDGGESQAMLSNLTPGVTYQVTVIAVKGLE 1396
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpDDGITGYIVGYRVEyreEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 922304343 1397 ES 1398
Cdd:smart00060 82 EG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1050-1128 |
7.62e-11 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 60.12 E-value: 7.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1050 DPPKDLQVSETTETTLALVWRRPV---AKIDTYSLVFIPADG--DKTELKIPGAANTYILTGLNPGMLHTITLTAERGRK 1124
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 922304343 1125 MSAP 1128
Cdd:pfam00041 81 EGPP 84
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
689-760 |
8.08e-11 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 59.74 E-value: 8.08e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922304343 689 SPPRDLTVTEVDPETVDVAW----VNEMLVTEYLITYVPTAPGGLEMEMRVSGEKKTATIRELEPGIEYLISVFAV 760
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtpppDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV 76
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
868-948 |
1.10e-10 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 59.35 E-value: 1.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 868 DAPSQVDVRDVTDTTALVTWLQPV---AQVDGISVSYGPNTDSSDRNTIELSSIETQYHLAELSPDTEYEVSLMARRGEM 944
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 922304343 945 SSFP 948
Cdd:pfam00041 81 EGPP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
689-775 |
1.90e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 59.05 E-value: 1.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 689 SPPRDLTVTEVDPETVDVAWV----NEMLVTEYLITYVPTAPGGLEMEMRVSGEKKTATIRELEPGIEYLISVFAVLNSK 764
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTppedDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|.
gi 922304343 765 MSVPVSARIAT 775
Cdd:cd00063 82 ESPPSESVTVT 92
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1498-1568 |
3.57e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 58.01 E-value: 3.57e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922304343 1498 DAPQNLAASNIQTETAMLTWKPPRAD-----ISGYILSFESADGVVKEVVLSPTATFYSMSQLTASTEYTVKLQAI 1568
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1498-1583 |
3.72e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 58.28 E-value: 3.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1498 DAPQNLAASNIQTETAMLTWKPPRAD---ISGYILSFESADG--VVKEVVLSPTATFYSMSQLTASTEYTVKLQAIAGPK 1572
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSgdWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|.
gi 922304343 1573 RSRVISTVFLT 1583
Cdd:cd00063 82 ESPPSESVTVT 92
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1050-1130 |
4.75e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 57.89 E-value: 4.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1050 DPPKDLQVSETTETTLALVWRRPV---AKIDTYSLVFIPADGDKTEL--KIPGAANTYILTGLNPGMLHTITLTAERGRK 1124
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEveVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
....*.
gi 922304343 1125 MSAPAT 1130
Cdd:cd00063 82 ESPPSE 87
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1231-1303 |
9.17e-10 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 57.04 E-value: 9.17e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922304343 1231 PEVEHITVSDITPHSFKVTWTAPE---AVFDSFALKVLDSSGLGRPHQISVSGDKRTEAVTGLNEDTDYEIELFGI 1303
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV 76
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1410-1495 |
1.39e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 56.74 E-value: 1.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1410 DKPRGLTAVNISDTEALLLWQP---SIATVDGYVITYSADSVAPVME--RVSGNTVEFEMSSLTPATLYTVKVYAFRDTA 1484
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPpedDGGPITGYVVEYREKGSGDWKEveVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 922304343 1485 KSA-ATSTDFTT 1495
Cdd:cd00063 82 ESPpSESVTVTT 93
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
868-955 |
1.46e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 56.74 E-value: 1.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 868 DAPSQVDVRDVTDTTALVTWLQPV---AQVDGISVSYGPNTDSSDRNTIELSSIETQYHLAELSPDTEYEVSLMARRGEM 944
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 922304343 945 SSFPIY-ETFTT 955
Cdd:cd00063 82 ESPPSEsVTVTT 93
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1184-1563 |
1.66e-09 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 62.71 E-value: 1.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1184 NHTLSGQEFSLAVTDLSPST--FYRVTLYGLYKGELLDPVFAEAITEAEPEVEH-ITVSDITPHSFKVTWTAPEAV-FDS 1259
Cdd:COG3401 184 SLTVTSTTLVDGGGDIEPGTtyYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTgLTATADTPGSVTLSWDPVTESdATG 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1260 FALKVlDSSGLGRPHQISVSgdKRTEAV-TGLNEDTDYEIELFGI----ILGRKFQPI-FTVARTGLGTPKGIRFSDVTD 1333
Cdd:COG3401 264 YRVYR-SNSGDGPFTKVATV--TTTSYTdTGLTNGTTYYYRVTAVdaagNESAPSNVVsVTTDLTPPAAPSGLTATAVGS 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1334 TSATVHWTMPHT-RVDNYRVIYVPIQGGSPLTLRVDGGESQAMLSNLTPGVTYQVTVIAV-KGLEESEPGSERVTTALDK 1411
Cdd:COG3401 341 SSITLSWTASSDaDVTGYNVYRSTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVdAAGNESAPSEEVSATTASA 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1412 PRGLTAVNISDTEALLLWQP-SIATVDGYVITYSADSVAPVMERVSGNTVEfEMSSLTPATLYTVKVYAFRDTAKSAATS 1490
Cdd:COG3401 421 ASGESLTASVDAVPLTDVAGaTAAASAASNPGVSAAVLADGGDTGNAVPFT-TTSSTVTATTTDTTTANLSVTTGSLVGG 499
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 922304343 1491 TDFTTDVDAPQNLAASNIQTETAMLTWKPPRADISGYILSFESADGVVKEVVLSPTATFYSMSQLTASTEYTV 1563
Cdd:COG3401 500 SGASSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLITDLVSLTTSASSSVSGAGLGSGNLY 572
|
|
| GGGWT_bact |
NF040941 |
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ... |
1594-1633 |
3.36e-09 |
|
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.
Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 54.11 E-value: 3.36e-09
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 922304343 1594 CSQALLNG-DTTSGLYTIYLRGDES-QPLQVYCDMTTDGGGW 1633
Cdd:NF040941 2 CWEILQAGpSAPSGVYWIDPDGMGGlAPFQVYCDMTTDGGGW 43
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
958-1040 |
5.27e-09 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 54.73 E-value: 5.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 958 DSPKHLKAIEQTDESITLEW---RNSRANVLNYRVKYGPLSGGEHG-ELVFPSglqDTTQAKITGLRPGTEYGMGVTSIK 1033
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYRPKNSGEPWnEITVPG---TTTSVTLTGLKPGTEYEVRVQAVN 77
|
....*..
gi 922304343 1034 EERESLP 1040
Cdd:pfam00041 78 GGGEGPP 84
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1050-1123 |
7.08e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 54.54 E-value: 7.08e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922304343 1050 DPPKDLQVSETTETTLALVWRRP-----VAKIDTYSLVFIPADGDKTELKIPGAANTYILTGLNPGMLHTITLTAERGR 1123
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
689-760 |
1.32e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.77 E-value: 1.32e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922304343 689 SPPRDLTVTEVDPETVDVAW--VNEMLVTEYLITYVP--TAPGGLEMEMRVSGEKKTATIRELEPGIEYLISVFAV 760
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWepPPDDGITGYIVGYRVeyREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
958-1038 |
1.71e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.39 E-value: 1.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 958 DSPKHLKAIEQTDESITLEWRN-SRANVLNYRVKYGPLSGGEHGELVFPSGLQDTTQAKITGLRPGTEYGMGVTSIKEER 1036
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPpPDDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 922304343 1037 ES 1038
Cdd:smart00060 82 EG 83
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
868-946 |
6.26e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 51.85 E-value: 6.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 868 DAPSQVDVRDVTDTTALVTWLQPV-AQVDGISVSYGPNTDSSDRNTIEL--SSIETQYHLAELSPDTEYEVSLMARRGEM 944
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPdDGITGYIVGYRVEYREEGSEWKEVnvTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 922304343 945 SS 946
Cdd:smart00060 82 EG 83
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
734-1102 |
3.21e-07 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 55.39 E-value: 3.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 734 RVSGEKKTATIRELEPGIEYLISVFAV---LNSKMSVPVSARIATHLPE-PEGLKFKSVKETSVEVEWDP-LNIPFDGWN 808
Cdd:COG3401 186 TVTSTTLVDGGGDIEPGTTYYYRVAATdtgGESAPSNEVSVTTPTTPPSaPTGLTATADTPGSVTLSWDPvTESDATGYR 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 809 lIFR-NTKEEDGEILNSLAppETTFEQSGLGPGQEYEVKLEVV-KNNTRGPPASKNVVTMI----DAPSQVDVRDVTDTT 882
Cdd:COG3401 266 -VYRsNSGDGPFTKVATVT--TTSYTDTGLTNGTTYYYRVTAVdAAGNESAPSNVVSVTTDltppAAPSGLTATAVGSSS 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 883 ALVTWlQPVAQVDGIS--VSYGPNTDSSDRNTIELSSiETQYHLAELSPDTEYEVSLMAR--RGEMS--SFPIYETFTTD 956
Cdd:COG3401 343 ITLSW-TASSDADVTGynVYRSTSGGGTYTKIAETVT-TTSYTDTGLTPGTTYYYKVTAVdaAGNESapSEEVSATTASA 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 957 LDSPKHLKAIEQTDESITLEWRNSRANVLNYRVKYGPLSGGEHGELVFPSGlqDTTQAKITGLRPGTEYGMGVTSIkeer 1036
Cdd:COG3401 421 ASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFT--TTSSTVTATTTDTTTANLSVTTG---- 494
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922304343 1037 eSLPATTNAVTDLDPPKDLQVSETTETTLALVWRRPVAKIDTYSLVFIPADGDKTELKIPGAANTY 1102
Cdd:COG3401 495 -SLVGGSGASSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLITDLVSLTTSASS 559
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1410-1482 |
6.28e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.76 E-value: 6.28e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922304343 1410 DKPRGLTAVNISDTEALLLWQPSIAT-----VDGYVITYSADSVAPVMERVSGNTVEFEMSSLTPATLYTVKVYAFRD 1482
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1140-1215 |
1.13e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 48.26 E-value: 1.13e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922304343 1140 PQVGNITISDVSWDSFSMSWD---LDRGEVEGFLIEVSDPDGLSDGQNHTLSGQEFSLAVTDLSPSTFYRVTLYGLYKG 1215
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTppeDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1233-1303 |
2.91e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 47.11 E-value: 2.91e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 922304343 1233 VEHITVSDITPHSFKVTWTAPE---AVFDSFALKVLDSSGlGRPHQISVSGDKRTEA-VTGLNEDTDYEIELFGI 1303
Cdd:cd00063 4 PTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGS-GDWKEVEVTPGSETSYtLTGLKPGTEYEFRVRAV 77
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1231-1300 |
1.45e-05 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 44.91 E-value: 1.45e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 922304343 1231 PEVEHITVSDITPHSFKVTWTAPE-AVFDSFAL--KVLDSSGLGRPHQISVSGDKRTEAVTGLNEDTDYEIEL 1300
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPdDGITGYIVgyRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRV 74
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
778-856 |
2.66e-05 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 44.14 E-value: 2.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 778 PEPEGLKFKSVKETSVEVEWDPLNIPFDGWNLIF---RNTKEEDGEILNSLAPPETTFEQSGLGPGQEYEVKLEVVKNNT 854
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGyrvEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 922304343 855 RG 856
Cdd:smart00060 82 EG 83
|
|
| PRK10767 |
PRK10767 |
chaperone protein DnaJ; Provisional |
471-544 |
3.78e-05 |
|
chaperone protein DnaJ; Provisional
Pssm-ID: 236757 [Multi-domain] Cd Length: 371 Bit Score: 48.22 E-value: 3.78e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 922304343 471 KTCPHhCHGHGQcVDGKcichKGFAgedcSI-KTCPnHCHGQGQCIDGKCichdgfagedcsiktcpNHCHGRGR 544
Cdd:PRK10767 160 KTCPT-CHGAGQ-VRMQ----QGFF----TVqQTCP-TCHGRGKIIKDPC-----------------KKCHGQGR 206
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
318-345 |
2.42e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.97 E-value: 2.42e-04
10 20
....*....|....*....|....*...
gi 922304343 318 CPQNCNHHGRCVNGQCICNIGYSGEDCS 345
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
380-407 |
2.42e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.97 E-value: 2.42e-04
10 20
....*....|....*....|....*...
gi 922304343 380 CPDNCNGRGHCVNGECICGPGYEGDDCS 407
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1140-1215 |
2.84e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 41.45 E-value: 2.84e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922304343 1140 PQVGNITISDVSWDSFSMSWD-LDRGEVEGFLIE--VSDPDGLSDGQNHTLSGQEFSLAVTDLSPSTFYRVTLYGLYKG 1215
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEpPPDDGITGYIVGyrVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
1412-1782 |
7.07e-04 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 43.99 E-value: 7.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1412 PRGLTAVNISDTEALLLWQPSIAT--VDGYVITYSADSVApvmerVSGNTVEFEMSSLTPATLYTVKVYAfRDTA-KSAA 1488
Cdd:COG3979 6 PTGLTASNVTSSSVSLSWDASTDNvgVTGYDVYRGGDQVA-----TVTGLTAWTVTGLTPGTEYTFTVGA-CDAAgNVSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1489 TSTDFTTDVDAPQNLAASNIQTETAMLTWKPPRADISGYILSFESADGVVKEVVLSPTATFYSMSQLTASTEYTVKLQAI 1568
Cdd:COG3979 80 ASGTSTAMFGGSSTTLGSAEGVADTSGNLAASGAFFGVTTPPTPSSTLVVDGTTTVNAAATANGGTGGSGGTTTIITTGV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1569 AGPkrSRVISTVFLTIGVLYKHPKDCSQALLNGDTTSGLYTIYLRGDESQPLQVYCDmTTDGGGWIVFVRRQSGKVEFFR 1648
Cdd:COG3979 160 EGG--GGSKTAQSLNAITAAGTAALNGGVVGGADEVLTCSAVKDDGSGGAGAGNTYW-ALNTLGVSDTPSGTTATGGTVG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1649 NWKNYTAGFGDLNDEFWLGLSNLHKITSFGQYELRVDLRDkgesAYAQYDKFSISEPRARYKVHVGGYSGTAGDSMTYHH 1728
Cdd:COG3979 237 ITSAYGAGVSGNAAVNVNAGFVVGNVGGAAGNTGTTSGTA----TSDAATNDVGDAAVTGLNDGAANGPTGGYGATGTTV 312
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 922304343 1729 GRPFSTYDNDNDIAVTNCALSYKGAFWYKNCHRVNIMGRYGDNSHSKGVNWFHW 1782
Cdd:COG3979 313 AGAAGVGGTKSGTGALGLSGAGGAGAAVSGTATGDDDAGADDSTAGVSGAGSTT 366
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
659-686 |
8.10e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.43 E-value: 8.10e-04
10 20
....*....|....*....|....*...
gi 922304343 659 CPADCNDQGQCLNGMCICDLGFTGDDCS 686
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
1322-1565 |
1.16e-03 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 43.22 E-value: 1.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1322 TPKGIRFSDVTDTSATVHWTmPHTrvDNYRVIYVPI-QGGSplTLRVDGGESQAMLSNLTPGVTYQVTVIAV--KGLEES 1398
Cdd:COG3979 5 APTGLTASNVTSSSVSLSWD-AST--DNVGVTGYDVyRGGD--QVATVTGLTAWTVTGLTPGTEYTFTVGACdaAGNVSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1399 EPGSERVTTALDKPRGLTAVNISDTEALLLWQPSIATVDGYVITYSADSVAPVMERVSGNTVEFEMSSLTPATLYTVKVY 1478
Cdd:COG3979 80 ASGTSTAMFGGSSTTLGSAEGVADTSGNLAASGAFFGVTTPPTPSSTLVVDGTTTVNAAATANGGTGGSGGTTTIITTGV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922304343 1479 AFRDTAKSAATSTDFTTDVDAPQNLAASNIQTETamLTWKPPRADISGYILSFESADGVVKEVVLSPTATFYSMSQLTAS 1558
Cdd:COG3979 160 EGGGGSKTAQSLNAITAAGTAALNGGVVGGADEV--LTCSAVKDDGSGGAGAGNTYWALNTLGVSDTPSGTTATGGTVGI 237
|
....*..
gi 922304343 1559 TEYTVKL 1565
Cdd:COG3979 238 TSAYGAG 244
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
535-562 |
2.06e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.28 E-value: 2.06e-03
10 20
....*....|....*....|....*...
gi 922304343 535 CPNHCHGRGRCVDGKCICHDGFAGEDCN 562
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
597-623 |
2.25e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.28 E-value: 2.25e-03
10 20
....*....|....*....|....*..
gi 922304343 597 CPNDCHNRGRCVNGQCVCNIGFTGEDC 623
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
256-283 |
2.71e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.89 E-value: 2.71e-03
10 20
....*....|....*....|....*...
gi 922304343 256 CPSNCLGRGRCVDDECVCDEPWTGFDCS 283
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
628-655 |
2.74e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.89 E-value: 2.74e-03
10 20
....*....|....*....|....*...
gi 922304343 628 CPNNCLDRGFCEDGKCVCFEGYTGEDCS 655
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
473-500 |
3.08e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.89 E-value: 3.08e-03
10 20
....*....|....*....|....*...
gi 922304343 473 CPHHCHGHGQCVDGKCICHKGFAGEDCS 500
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
504-531 |
3.75e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.51 E-value: 3.75e-03
10 20
....*....|....*....|....*...
gi 922304343 504 CPNHCHGQGQCIDGKCICHDGFAGEDCS 531
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
566-593 |
4.31e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.51 E-value: 4.31e-03
10 20
....*....|....*....|....*...
gi 922304343 566 CPNDCHDHGECVDGKCICHAGFTGHDCS 593
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
225-252 |
6.77e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 35.74 E-value: 6.77e-03
10 20
....*....|....*....|....*...
gi 922304343 225 CPVDCGENGECIDGACICAEGFIGEDCS 252
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
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