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Conserved domains on  [gi|808357196|ref|NP_001294126|]
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Fibronectin type-III domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 70-160 6.72e-18

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 79.46  E-value: 6.72e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   70 PLAPGRPTVIAVDGQGVLLEWTPPVADvhSSPPQGYQVEYRVYGSRDWIVANEQLVQENVFTVESLRPNGVYEFRVRGKN 149
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPPEDD--GGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|.
gi 808357196  150 QDGLGHPSMSS 160
Cdd:cd00063    79 GGGESPPSESV 89
FN3 super family cl27307
Fibronectin type 3 domain [General function prediction only];
16-270 3.31e-13

Fibronectin type 3 domain [General function prediction only];


The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 73.50  E-value: 3.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   16 SYAVVDEEVTNLTSHEVQFRVSAYGRTGFGPASNPslpvkipISETDLATsagAPLAPGRPTVIAVDGQGVLLEWTP-PV 94
Cdd:COG3401   189 STTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNE-------VSVTTPTT---PPSAPTGLTATADTPGSVTLSWDPvTE 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   95 ADVhssppQGYQVEYRVYGSRDW-IVANeqlVQENVFTVESLRPNGVYEFRVRGKNQDGLghPSMSSGGVairpaapqrh 173
Cdd:COG3401   259 SDA-----TGYRVYRSNSGDGPFtKVAT---VTTTSYTDTGLTNGTTYYYRVTAVDAAGN--ESAPSNVV---------- 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  174 vparKVSESVQPPGQPQMVEV---GDDVVKLEWAPSVQN--ARYIVEYREVGDPEWHTANyDPIVQNGIQVEGLHRNSTY 248
Cdd:COG3401   319 ----SVTTDLTPPAAPSGLTAtavGSSSITLSWTASSDAdvTGYNVYRSTSGGGTYTKIA-ETVTTTSYTDTGLTPGTTY 393

                         250       260
                  ....*....|....*....|...
gi 808357196  249 EFCVISI-VDNIASQPSETSDII 270
Cdd:COG3401   394 YYKVTAVdAAGNESAPSEEVSAT 416
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 285-376 1.27e-11

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 61.74  E-value: 1.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  285 PNILEAPEFLEVDGDKITICW-LPAQSQLPVMGYDVEFRDLQqDDRWYKVNDQPVFACKMTVGDLIMDHDYQFRVLAHNA 363
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWtPPEDDGGPITGYVVEYREKG-SGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                          90
                  ....*....|...
gi 808357196  364 SGCSQPSPPSDFV 376
Cdd:cd00063    80 GGESPPSESVTVT 92
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 479-518 3.15e-07

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


:

Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 47.45  E-value: 3.15e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 808357196   479 DNQIKEETREYGGIPKLIALLRSDTPRIQKNACACLKNLS 518
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
PLN03200 super family cl33659
cellulose synthase-interactive protein; Provisional
 448-655 4.21e-07

cellulose synthase-interactive protein; Provisional


The actual alignment was detected with superfamily member PLN03200:

Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 54.34  E-value: 4.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  448 PSLKEVIEYLSSADKDKQLNASGYLQHLTYTDNQIKEETREYGGIPKLIALLRSDTPRIQKNACACLKNLSFGKENDANK 527
Cdd:PLN03200  147 PSLWDQLQPGNKQDKVVEGLLTGALRNLCGSTDGFWSATLEAGGVDILVKLLSSGNSDAQANAASLLARLMMAFESSISK 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  528 laVMEADGVRLIAEVLRTTHDASVKEEAAAALWNLSSADMlkpvilESATEILSQQVIaPVLAVGTSDPTRHF-----GS 602
Cdd:PLN03200  227 --VLDAGAVKQLLKLLGQGNEVSVRAEAAGALEALSSQSK------EAKQAIADAGGI-PALINATVAPSKEFmqgefAQ 297

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 808357196  603 TLFKNSTGVLRNVSAAsqqarrrlrdipnlIEALVHFLTHAIQKSQVDSPTVE 655
Cdd:PLN03200  298 ALQENAMGALANICGG--------------MSALILYLGELSESPRSPAPIAD 336
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 721-756 5.07e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


:

Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.51  E-value: 5.07e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 808357196   721 VLWQPHVVKLYLKLLQdSSNIETLEASAGAIQNLAA 756
Cdd:pfam00514    7 AVIEAGAVPPLVRLLS-SPDEEVQEEAAWALSNLAA 41
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 70-160 6.72e-18

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 79.46  E-value: 6.72e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   70 PLAPGRPTVIAVDGQGVLLEWTPPVADvhSSPPQGYQVEYRVYGSRDWIVANEQLVQENVFTVESLRPNGVYEFRVRGKN 149
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPPEDD--GGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|.
gi 808357196  150 QDGLGHPSMSS 160
Cdd:cd00063    79 GGGESPPSESV 89
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 70-154 5.76e-14

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 68.02  E-value: 5.76e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196     70 PLAPGRPTVIAVDGQGVLLEWTPPVADVHSSPPQGYQVEYRVyGSRDWIVANEQlVQENVFTVESLRPNGVYEFRVRGKN 149
Cdd:smart00060    1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYRE-EGSEWKEVNVT-PSSTSYTLTGLKPGTEYEFRVRAVN 78


                    ....*
gi 808357196    150 QDGLG 154
Cdd:smart00060   79 GAGEG 83
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
16-270 3.31e-13

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 73.50  E-value: 3.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   16 SYAVVDEEVTNLTSHEVQFRVSAYGRTGFGPASNPslpvkipISETDLATsagAPLAPGRPTVIAVDGQGVLLEWTP-PV 94
Cdd:COG3401   189 STTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNE-------VSVTTPTT---PPSAPTGLTATADTPGSVTLSWDPvTE 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   95 ADVhssppQGYQVEYRVYGSRDW-IVANeqlVQENVFTVESLRPNGVYEFRVRGKNQDGLghPSMSSGGVairpaapqrh 173
Cdd:COG3401   259 SDA-----TGYRVYRSNSGDGPFtKVAT---VTTTSYTDTGLTNGTTYYYRVTAVDAAGN--ESAPSNVV---------- 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  174 vparKVSESVQPPGQPQMVEV---GDDVVKLEWAPSVQN--ARYIVEYREVGDPEWHTANyDPIVQNGIQVEGLHRNSTY 248
Cdd:COG3401   319 ----SVTTDLTPPAAPSGLTAtavGSSSITLSWTASSDAdvTGYNVYRSTSGGGTYTKIA-ETVTTTSYTDTGLTPGTTY 393

                         250       260
                  ....*....|....*....|...
gi 808357196  249 EFCVISI-VDNIASQPSETSDII 270
Cdd:COG3401   394 YYKVTAVdAAGNESAPSEEVSAT 416
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 185-270 8.52e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 62.13  E-value: 8.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  185 PPGQPQMVEVGDDVVKLEWAPSVQNAR----YIVEYREVGDPEWHTANYDPIVQNGIQVEGLHRNSTYEFCVISIVDNIA 260
Cdd:cd00063     3 PPTNLRVTDVTSTSVTLSWTPPEDDGGpitgYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82

                          90
                  ....*....|
gi 808357196  261 SQPSETSDII 270
Cdd:cd00063    83 SPPSESVTVT 92
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 285-376 1.27e-11

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 61.74  E-value: 1.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  285 PNILEAPEFLEVDGDKITICW-LPAQSQLPVMGYDVEFRDLQqDDRWYKVNDQPVFACKMTVGDLIMDHDYQFRVLAHNA 363
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWtPPEDDGGPITGYVVEYREKG-SGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                          90
                  ....*....|...
gi 808357196  364 SGCSQPSPPSDFV 376
Cdd:cd00063    80 GGESPPSESVTVT 92
fn3 pfam00041
Fibronectin type III domain;
72-157 1.71e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 61.28  E-value: 1.71e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196    72 APGRPTVIAVDGQGVLLEWTPPvaDVHSSPPQGYQVEYR-VYGSRDWivaNEQLV--QENVFTVESLRPNGVYEFRVRGK 148
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPP--PDGNGPITGYEVEYRpKNSGEPW---NEITVpgTTTSVTLTGLKPGTEYEVRVQAV 76


                   ....*....
gi 808357196   149 NQDGLGHPS 157
Cdd:pfam00041   77 NGGGEGPPS 85
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 479-518 3.15e-07

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 47.45  E-value: 3.15e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 808357196   479 DNQIKEETREYGGIPKLIALLRSDTPRIQKNACACLKNLS 518
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 448-655 4.21e-07

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 54.34  E-value: 4.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  448 PSLKEVIEYLSSADKDKQLNASGYLQHLTYTDNQIKEETREYGGIPKLIALLRSDTPRIQKNACACLKNLSFGKENDANK 527
Cdd:PLN03200  147 PSLWDQLQPGNKQDKVVEGLLTGALRNLCGSTDGFWSATLEAGGVDILVKLLSSGNSDAQANAASLLARLMMAFESSISK 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  528 laVMEADGVRLIAEVLRTTHDASVKEEAAAALWNLSSADMlkpvilESATEILSQQVIaPVLAVGTSDPTRHF-----GS 602
Cdd:PLN03200  227 --VLDAGAVKQLLKLLGQGNEVSVRAEAAGALEALSSQSK------EAKQAIADAGGI-PALINATVAPSKEFmqgefAQ 297

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 808357196  603 TLFKNSTGVLRNVSAAsqqarrrlrdipnlIEALVHFLTHAIQKSQVDSPTVE 655
Cdd:PLN03200  298 ALQENAMGALANICGG--------------MSALILYLGELSESPRSPAPIAD 336
fn3 pfam00041
Fibronectin type III domain;
185-264 4.99e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 48.57  E-value: 4.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   185 PPGQPQMVEVGDDVVKLEWAPSVQN----ARYIVEYREVGDPE-WHTANyDPIVQNGIQVEGLHRNSTYEFCVISIVDNI 259
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPPDGngpiTGYEVEYRPKNSGEpWNEIT-VPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*
gi 808357196   260 ASQPS 264
Cdd:pfam00041   81 EGPPS 85
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 479-519 5.03e-07

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 47.04  E-value: 5.03e-07
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|.
gi 808357196    479 DNQIKEETREYGGIPKLIALLRSDTPRIQKNACACLKNLSF 519
Cdd:smart00185    1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 185-255 2.45e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 46.45  E-value: 2.45e-06
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 808357196    185 PPGQPQMVEVGDDVVKLEWAPSVQNA--RYIVEYREVG---DPEWHTANYDPIvQNGIQVEGLHRNSTYEFCVISI 255
Cdd:smart00060    3 PPSNLRVTDVTSTSVTLSWEPPPDDGitGYIVGYRVEYreeGSEWKEVNVTPS-STSYTLTGLKPGTEYEFRVRAV 77
fn3 pfam00041
Fibronectin type III domain;
283-370 1.01e-05

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 44.71  E-value: 1.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   283 PAPNILEapeFLEVDGDKITICWL-PAQSQLPVMGYDVEFRDL--QQDDRWYKVNDQPVFackMTVGDLIMDHDYQFRVL 359
Cdd:pfam00041    1 SAPSNLT---VTDVTSTSLTVSWTpPPDGNGPITGYEVEYRPKnsGEPWNEITVPGTTTS---VTLTGLKPGTEYEVRVQ 74

                           90
                   ....*....|.
gi 808357196   360 AHNASGCSQPS 370
Cdd:pfam00041   75 AVNGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 291-367 1.50e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 44.14  E-value: 1.50e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 808357196    291 PEFLEVDGDKITICWLPAQSQlPVMGYDVEFR--DLQQDDRWYKVNDQPVfACKMTVGDLIMDHDYQFRVLAHNASGCS 367
Cdd:smart00060    7 LRVTDVTSTSVTLSWEPPPDD-GITGYIVGYRveYREEGSEWKEVNVTPS-STSYTLTGLKPGTEYEFRVRAVNGAGEG 83
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
23-152 6.14e-05

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 47.25  E-value: 6.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   23 EVTNLTSHEVQFRVSAYGRtgFGPASNPSLPvkipiSETDLATSAGAPLAPGRPTVIAVDGqGVLLEWTPPV-ADVhssp 101
Cdd:COG4733   590 EVPGIYAGDYEVRVRAINA--LGVSSAWAAS-----SETTVTGKTAPPPAPTGLTATGGLG-GITLSWSFPVdADT---- 657

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 808357196  102 pQGYQVEYRVYGSRDWIVANEQLVQENVFTVESLRPNGVYEFRVRGKNQDG 152
Cdd:COG4733   658 -LRTEIRYSTTGDWASATVAQALYPGNTYTLAGLKAGQTYYYRARAVDRSG 707
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 523-564 7.37e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 40.90  E-value: 7.37e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 808357196   523 NDANKLAVMEADGVRLIAEVLRTThDASVKEEAAAALWNLSS 564
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSP-DEEVQEEAAWALSNLAA 41
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
490-588 1.65e-03

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 42.18  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  490 GGIPKLIALLRSDTPRIQKNACACLKNLSFGKENDANklAVMEADGVRLIAEVLrTTHDASVKEEAAAALWNLSSADMLK 569
Cdd:COG5064   327 GALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIQ--AVIDANLIPPLIHLL-SSAEYKIKKEACWAISNATSGGLNR 403

                          90
                  ....*....|....*....
gi 808357196  570 PVILESateILSQQVIAPV 588
Cdd:COG5064   404 PDIIRY---LVSQGFIKPL 419
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 721-756 5.07e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.51  E-value: 5.07e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 808357196   721 VLWQPHVVKLYLKLLQdSSNIETLEASAGAIQNLAA 756
Cdd:pfam00514    7 AVIEAGAVPPLVRLLS-SPDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 523-564 5.99e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.48  E-value: 5.99e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 808357196    523 NDANKLAVMEADGVRLIAEVLRTTHDaSVKEEAAAALWNLSS 564
Cdd:smart00185    1 DDENKQAVVDAGGLPALVELLKSEDE-EVVKEAAWALSNLSS 41
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 70-160 6.72e-18

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 79.46  E-value: 6.72e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   70 PLAPGRPTVIAVDGQGVLLEWTPPVADvhSSPPQGYQVEYRVYGSRDWIVANEQLVQENVFTVESLRPNGVYEFRVRGKN 149
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPPEDD--GGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|.
gi 808357196  150 QDGLGHPSMSS 160
Cdd:cd00063    79 GGGESPPSESV 89
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 70-154 5.76e-14

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 68.02  E-value: 5.76e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196     70 PLAPGRPTVIAVDGQGVLLEWTPPVADVHSSPPQGYQVEYRVyGSRDWIVANEQlVQENVFTVESLRPNGVYEFRVRGKN 149
Cdd:smart00060    1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYRE-EGSEWKEVNVT-PSSTSYTLTGLKPGTEYEFRVRAVN 78


                    ....*
gi 808357196    150 QDGLG 154
Cdd:smart00060   79 GAGEG 83
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
16-270 3.31e-13

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 73.50  E-value: 3.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   16 SYAVVDEEVTNLTSHEVQFRVSAYGRTGFGPASNPslpvkipISETDLATsagAPLAPGRPTVIAVDGQGVLLEWTP-PV 94
Cdd:COG3401   189 STTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNE-------VSVTTPTT---PPSAPTGLTATADTPGSVTLSWDPvTE 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   95 ADVhssppQGYQVEYRVYGSRDW-IVANeqlVQENVFTVESLRPNGVYEFRVRGKNQDGLghPSMSSGGVairpaapqrh 173
Cdd:COG3401   259 SDA-----TGYRVYRSNSGDGPFtKVAT---VTTTSYTDTGLTNGTTYYYRVTAVDAAGN--ESAPSNVV---------- 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  174 vparKVSESVQPPGQPQMVEV---GDDVVKLEWAPSVQN--ARYIVEYREVGDPEWHTANyDPIVQNGIQVEGLHRNSTY 248
Cdd:COG3401   319 ----SVTTDLTPPAAPSGLTAtavGSSSITLSWTASSDAdvTGYNVYRSTSGGGTYTKIA-ETVTTTSYTDTGLTPGTTY 393

                         250       260
                  ....*....|....*....|...
gi 808357196  249 EFCVISI-VDNIASQPSETSDII 270
Cdd:COG3401   394 YYKVTAVdAAGNESAPSEEVSAT 416
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 185-270 8.52e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 62.13  E-value: 8.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  185 PPGQPQMVEVGDDVVKLEWAPSVQNAR----YIVEYREVGDPEWHTANYDPIVQNGIQVEGLHRNSTYEFCVISIVDNIA 260
Cdd:cd00063     3 PPTNLRVTDVTSTSVTLSWTPPEDDGGpitgYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82

                          90
                  ....*....|
gi 808357196  261 SQPSETSDII 270
Cdd:cd00063    83 SPPSESVTVT 92
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 285-376 1.27e-11

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 61.74  E-value: 1.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  285 PNILEAPEFLEVDGDKITICW-LPAQSQLPVMGYDVEFRDLQqDDRWYKVNDQPVFACKMTVGDLIMDHDYQFRVLAHNA 363
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWtPPEDDGGPITGYVVEYREKG-SGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                          90
                  ....*....|...
gi 808357196  364 SGCSQPSPPSDFV 376
Cdd:cd00063    80 GGESPPSESVTVT 92
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
36-393 1.51e-11

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 68.49  E-value: 1.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   36 VSAYGRTGFGPASNPSLPVKIPISETDLATSAGAPLAPGRPTVIAVDG-QGVLLEWTPPVADVHSSPPQGYQVEYRVYGS 114
Cdd:COG3401    99 GSGSVGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGlYGVDGANASGTTASSVAGAGVVVSPDTSATA 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  115 RDWIVANEQLVQENVFTVESLRPNGVYEFRVRGKNQDGLGHPSmssggvairpaapqrhvPARKVSESVQPPGQPQMVEV 194
Cdd:COG3401   179 AVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPS-----------------NEVSVTTPTTPPSAPTGLTA 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  195 ---GDDVVKLEWAPSVQN--ARYIVEYREVGDPEW------HTANY-DPIVQNGiqveglhrnSTYEFCVISI-VDNIAS 261
Cdd:COG3401   242 tadTPGSVTLSWDPVTESdaTGYRVYRSNSGDGPFtkvatvTTTSYtDTGLTNG---------TTYYYRVTAVdAAGNES 312

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  262 QPSETSdiihlrpTCNTSALRPApnileAPEFLEV---DGDKITICWLPAqSQLPVMGYDVEfRDLQQDDRWYKVN---D 335
Cdd:COG3401   313 APSNVV-------SVTTDLTPPA-----APSGLTAtavGSSSITLSWTAS-SDADVTGYNVY-RSTSGGGTYTKIAetvT 378

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 808357196  336 QPVFackmTVGDLIMDHDYQFRVLAHNASGCSqpSPPSDFVHIEPSTNRFSSDTMESP 393
Cdd:COG3401   379 TTSY----TDTGLTPGTTYYYKVTAVDAAGNE--SAPSEEVSATTASAASGESLTASV 430
fn3 pfam00041
Fibronectin type III domain;
72-157 1.71e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 61.28  E-value: 1.71e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196    72 APGRPTVIAVDGQGVLLEWTPPvaDVHSSPPQGYQVEYR-VYGSRDWivaNEQLV--QENVFTVESLRPNGVYEFRVRGK 148
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPP--PDGNGPITGYEVEYRpKNSGEPW---NEITVpgTTTSVTLTGLKPGTEYEVRVQAV 76


                   ....*....
gi 808357196   149 NQDGLGHPS 157
Cdd:pfam00041   77 NGGGEGPPS 85
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 479-518 3.15e-07

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 47.45  E-value: 3.15e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 808357196   479 DNQIKEETREYGGIPKLIALLRSDTPRIQKNACACLKNLS 518
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 448-655 4.21e-07

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 54.34  E-value: 4.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  448 PSLKEVIEYLSSADKDKQLNASGYLQHLTYTDNQIKEETREYGGIPKLIALLRSDTPRIQKNACACLKNLSFGKENDANK 527
Cdd:PLN03200  147 PSLWDQLQPGNKQDKVVEGLLTGALRNLCGSTDGFWSATLEAGGVDILVKLLSSGNSDAQANAASLLARLMMAFESSISK 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  528 laVMEADGVRLIAEVLRTTHDASVKEEAAAALWNLSSADMlkpvilESATEILSQQVIaPVLAVGTSDPTRHF-----GS 602
Cdd:PLN03200  227 --VLDAGAVKQLLKLLGQGNEVSVRAEAAGALEALSSQSK------EAKQAIADAGGI-PALINATVAPSKEFmqgefAQ 297

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 808357196  603 TLFKNSTGVLRNVSAAsqqarrrlrdipnlIEALVHFLTHAIQKSQVDSPTVE 655
Cdd:PLN03200  298 ALQENAMGALANICGG--------------MSALILYLGELSESPRSPAPIAD 336
fn3 pfam00041
Fibronectin type III domain;
185-264 4.99e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 48.57  E-value: 4.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   185 PPGQPQMVEVGDDVVKLEWAPSVQN----ARYIVEYREVGDPE-WHTANyDPIVQNGIQVEGLHRNSTYEFCVISIVDNI 259
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPPDGngpiTGYEVEYRPKNSGEpWNEIT-VPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*
gi 808357196   260 ASQPS 264
Cdd:pfam00041   81 EGPPS 85
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 479-519 5.03e-07

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 47.04  E-value: 5.03e-07
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|.
gi 808357196    479 DNQIKEETREYGGIPKLIALLRSDTPRIQKNACACLKNLSF 519
Cdd:smart00185    1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 185-255 2.45e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 46.45  E-value: 2.45e-06
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 808357196    185 PPGQPQMVEVGDDVVKLEWAPSVQNA--RYIVEYREVG---DPEWHTANYDPIvQNGIQVEGLHRNSTYEFCVISI 255
Cdd:smart00060    3 PPSNLRVTDVTSTSVTLSWEPPPDDGitGYIVGYRVEYreeGSEWKEVNVTPS-STSYTLTGLKPGTEYEFRVRAV 77
fn3 pfam00041
Fibronectin type III domain;
283-370 1.01e-05

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 44.71  E-value: 1.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   283 PAPNILEapeFLEVDGDKITICWL-PAQSQLPVMGYDVEFRDL--QQDDRWYKVNDQPVFackMTVGDLIMDHDYQFRVL 359
Cdd:pfam00041    1 SAPSNLT---VTDVTSTSLTVSWTpPPDGNGPITGYEVEYRPKnsGEPWNEITVPGTTTS---VTLTGLKPGTEYEVRVQ 74

                           90
                   ....*....|.
gi 808357196   360 AHNASGCSQPS 370
Cdd:pfam00041   75 AVNGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 291-367 1.50e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 44.14  E-value: 1.50e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 808357196    291 PEFLEVDGDKITICWLPAQSQlPVMGYDVEFR--DLQQDDRWYKVNDQPVfACKMTVGDLIMDHDYQFRVLAHNASGCS 367
Cdd:smart00060    7 LRVTDVTSTSVTLSWEPPPDD-GITGYIVGYRveYREEGSEWKEVNVTPS-STSYTLTGLKPGTEYEFRVRAVNGAGEG 83
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
23-152 6.14e-05

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 47.25  E-value: 6.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196   23 EVTNLTSHEVQFRVSAYGRtgFGPASNPSLPvkipiSETDLATSAGAPLAPGRPTVIAVDGqGVLLEWTPPV-ADVhssp 101
Cdd:COG4733   590 EVPGIYAGDYEVRVRAINA--LGVSSAWAAS-----SETTVTGKTAPPPAPTGLTATGGLG-GITLSWSFPVdADT---- 657

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 808357196  102 pQGYQVEYRVYGSRDWIVANEQLVQENVFTVESLRPNGVYEFRVRGKNQDG 152
Cdd:COG4733   658 -LRTEIRYSTTGDWASATVAQALYPGNTYTLAGLKAGQTYYYRARAVDRSG 707
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 523-564 7.37e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 40.90  E-value: 7.37e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 808357196   523 NDANKLAVMEADGVRLIAEVLRTThDASVKEEAAAALWNLSS 564
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSP-DEEVQEEAAWALSNLAA 41
Tissue_fac pfam01108
Tissue factor; This family is found in metazoa, and is very similar to the fibronectin type ...
 63-148 1.26e-03

Tissue factor; This family is found in metazoa, and is very similar to the fibronectin type III domain. The family is found in cytokine receptors, interleukin and interferon receptors and coagulation factor III proteins. It occurs multiple times, as does fn3, family pfam00041.


Pssm-ID: 460067  Cd Length: 107  Bit Score: 39.29  E-value: 1.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196    63 LATSAGAPLAPGRPTVIAVDGQGVLlEWTPpvaDVHSSPPQGYQVEYRVYGSRDWI-VANEQLVQENV--FTVESLRPNG 139
Cdd:pfam01108   15 SAAGGPSLPAPQNVTFQSTNFKNIL-TWEP---GPNSPPDVVYTVQYKIYGSGDWKnVPNCTNITRTEcdLTDETSDLTE 90


                   ....*....
gi 808357196   140 VYEFRVRGK 148
Cdd:pfam01108   91 TYYARVRAV 99
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
490-588 1.65e-03

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 42.18  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808357196  490 GGIPKLIALLRSDTPRIQKNACACLKNLSFGKENDANklAVMEADGVRLIAEVLrTTHDASVKEEAAAALWNLSSADMLK 569
Cdd:COG5064   327 GALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIQ--AVIDANLIPPLIHLL-SSAEYKIKKEACWAISNATSGGLNR 403

                          90
                  ....*....|....*....
gi 808357196  570 PVILESateILSQQVIAPV 588
Cdd:COG5064   404 PDIIRY---LVSQGFIKPL 419
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 721-756 5.07e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.51  E-value: 5.07e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 808357196   721 VLWQPHVVKLYLKLLQdSSNIETLEASAGAIQNLAA 756
Cdd:pfam00514    7 AVIEAGAVPPLVRLLS-SPDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 523-564 5.99e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.48  E-value: 5.99e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 808357196    523 NDANKLAVMEADGVRLIAEVLRTTHDaSVKEEAAAALWNLSS 564
Cdd:smart00185    1 DDENKQAVVDAGGLPALVELLKSEDE-EVVKEAAWALSNLSS 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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