NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|758818565|ref|NP_001292013|]
View 

alpha/beta-tubulin-N-acetyltransferase 9 isoform 8 [Homo sapiens]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 12134272)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.1.-
Gene Ontology:  GO:0008080
SCOP:  3000403

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
14-132 1.47e-12

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


:

Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 60.44  E-value: 1.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 758818565   14 VVLVPYTSEHVPsRYHEWMKSEELQRLTASEPLTLEQEYA-MQCSWQEDADK--CTFIVLDAEkwqaqpgateeSCMVGD 90
Cdd:pfam13302   2 LLLRPLTEEDAE-ALFELLSDPEVMRYGVPWPLTLEEAREwLARIWAADEAErgYGWAIELKD-----------TGFIGS 69
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 758818565   91 VNLFLTDLEDLTLgEIEVMIAePSCRGKGLGTEAVLAMLSYG 132
Cdd:pfam13302  70 IGLYDIDGEPERA-ELGYWLG-PDYWGKGYATEAVRALLEYA 109
 
Name Accession Description Interval E-value
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
14-132 1.47e-12

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 60.44  E-value: 1.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 758818565   14 VVLVPYTSEHVPsRYHEWMKSEELQRLTASEPLTLEQEYA-MQCSWQEDADK--CTFIVLDAEkwqaqpgateeSCMVGD 90
Cdd:pfam13302   2 LLLRPLTEEDAE-ALFELLSDPEVMRYGVPWPLTLEEAREwLARIWAADEAErgYGWAIELKD-----------TGFIGS 69
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 758818565   91 VNLFLTDLEDLTLgEIEVMIAePSCRGKGLGTEAVLAMLSYG 132
Cdd:pfam13302  70 IGLYDIDGEPERA-ELGYWLG-PDYWGKGYATEAVRALLEYA 109
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
9-132 6.77e-12

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 59.63  E-value: 6.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 758818565   9 LLGKKVVLVPYTSEHVPsRYHEWMKSEELQRLTASEPLTLEQEYAMQCSWQEDADKCTFIVLDAEKwqaqpgaTEESCMV 88
Cdd:COG1670    3 LETERLRLRPLRPEDAE-ALAELLNDPEVARYLPGPPYSLEEARAWLERLLADWADGGALPFAIED-------KEDGELI 74
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 758818565  89 GDVNLFLTDLEDLTlGEIEVMIAePSCRGKGLGTEAVLAMLSYG 132
Cdd:COG1670   75 GVVGLYDIDRANRS-AEIGYWLA-PAYWGKGYATEALRALLDYA 116
 
Name Accession Description Interval E-value
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
14-132 1.47e-12

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 60.44  E-value: 1.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 758818565   14 VVLVPYTSEHVPsRYHEWMKSEELQRLTASEPLTLEQEYA-MQCSWQEDADK--CTFIVLDAEkwqaqpgateeSCMVGD 90
Cdd:pfam13302   2 LLLRPLTEEDAE-ALFELLSDPEVMRYGVPWPLTLEEAREwLARIWAADEAErgYGWAIELKD-----------TGFIGS 69
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 758818565   91 VNLFLTDLEDLTLgEIEVMIAePSCRGKGLGTEAVLAMLSYG 132
Cdd:pfam13302  70 IGLYDIDGEPERA-ELGYWLG-PDYWGKGYATEAVRALLEYA 109
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
9-132 6.77e-12

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 59.63  E-value: 6.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 758818565   9 LLGKKVVLVPYTSEHVPsRYHEWMKSEELQRLTASEPLTLEQEYAMQCSWQEDADKCTFIVLDAEKwqaqpgaTEESCMV 88
Cdd:COG1670    3 LETERLRLRPLRPEDAE-ALAELLNDPEVARYLPGPPYSLEEARAWLERLLADWADGGALPFAIED-------KEDGELI 74
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 758818565  89 GDVNLFLTDLEDLTlGEIEVMIAePSCRGKGLGTEAVLAMLSYG 132
Cdd:COG1670   75 GVVGLYDIDRANRS-AEIGYWLA-PAYWGKGYATEALRALLDYA 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH