uncharacterized protein Dmel_CG8079, isoform E [Drosophila melanogaster]
Protein Classification
LCP family protein( domain architecture ID 10888443)
LytR-CpsA-Psr (LCP) family protein is implicated in the attachment of anionic polymers to cell wall peptidoglycan in bacteria
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| OCRE_VG5Q | cd16164 | OCRE domain found in angiogenic factor VG5Q and similar proteins; VG5Q, also called angiogenic ... |
124-177 | 2.20e-20 | ||
OCRE domain found in angiogenic factor VG5Q and similar proteins; VG5Q, also called angiogenic factor with G patch and FHA domains 1 (AGGF1), or G patch domain-containing protein 7, or vasculogenesis gene on 5q protein, functions as a potent angiogenic factor in promoting angiogenesis through interacting with TWEAK (also known as TNFSF12), which is a member of the tumor necrosis factor (TNF) superfamily that induces angiogenesis in vivo. VG5Q can bind to the surface of endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. The chromosomal translocation t(5;11) and the E133K variant in VG5Q are associated with Klippel-Trenaunay syndrome (KTS), a disorder characterized by diverse effects in the vascular system. In addition to a forkhead-associated (FHA) domain and a G-patch motif, VG5Q contains an N-terminal OCtamer REpeat (OCRE) domain that is characterized by a 5-fold, imperfectly repeated octameric sequence. : Pssm-ID: 293883 Cd Length: 54 Bit Score: 80.79 E-value: 2.20e-20
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| Name | Accession | Description | Interval | E-value | ||
| OCRE_VG5Q | cd16164 | OCRE domain found in angiogenic factor VG5Q and similar proteins; VG5Q, also called angiogenic ... |
124-177 | 2.20e-20 | ||
OCRE domain found in angiogenic factor VG5Q and similar proteins; VG5Q, also called angiogenic factor with G patch and FHA domains 1 (AGGF1), or G patch domain-containing protein 7, or vasculogenesis gene on 5q protein, functions as a potent angiogenic factor in promoting angiogenesis through interacting with TWEAK (also known as TNFSF12), which is a member of the tumor necrosis factor (TNF) superfamily that induces angiogenesis in vivo. VG5Q can bind to the surface of endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. The chromosomal translocation t(5;11) and the E133K variant in VG5Q are associated with Klippel-Trenaunay syndrome (KTS), a disorder characterized by diverse effects in the vascular system. In addition to a forkhead-associated (FHA) domain and a G-patch motif, VG5Q contains an N-terminal OCtamer REpeat (OCRE) domain that is characterized by a 5-fold, imperfectly repeated octameric sequence. Pssm-ID: 293883 Cd Length: 54 Bit Score: 80.79 E-value: 2.20e-20
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| OCRE | pfam17780 | OCRE domain; The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with ... |
131-177 | 1.22e-14 | ||
OCRE domain; The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with 12 tyrosine residues in the spliceosome trans-regulatory elements RBM5 and RBM10 (RBM [RNA-binding motif]), which are known to regulate alternative splicing of Fas and Bcl-x pre-mRNA transcripts. The structure of the domain consists of an anti-parallel arrangement of six beta strands. Pssm-ID: 465502 Cd Length: 51 Bit Score: 65.73 E-value: 1.22e-14
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| Name | Accession | Description | Interval | E-value | ||
| OCRE_VG5Q | cd16164 | OCRE domain found in angiogenic factor VG5Q and similar proteins; VG5Q, also called angiogenic ... |
124-177 | 2.20e-20 | ||
OCRE domain found in angiogenic factor VG5Q and similar proteins; VG5Q, also called angiogenic factor with G patch and FHA domains 1 (AGGF1), or G patch domain-containing protein 7, or vasculogenesis gene on 5q protein, functions as a potent angiogenic factor in promoting angiogenesis through interacting with TWEAK (also known as TNFSF12), which is a member of the tumor necrosis factor (TNF) superfamily that induces angiogenesis in vivo. VG5Q can bind to the surface of endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. The chromosomal translocation t(5;11) and the E133K variant in VG5Q are associated with Klippel-Trenaunay syndrome (KTS), a disorder characterized by diverse effects in the vascular system. In addition to a forkhead-associated (FHA) domain and a G-patch motif, VG5Q contains an N-terminal OCtamer REpeat (OCRE) domain that is characterized by a 5-fold, imperfectly repeated octameric sequence. Pssm-ID: 293883 Cd Length: 54 Bit Score: 80.79 E-value: 2.20e-20
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| OCRE | pfam17780 | OCRE domain; The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with ... |
131-177 | 1.22e-14 | ||
OCRE domain; The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with 12 tyrosine residues in the spliceosome trans-regulatory elements RBM5 and RBM10 (RBM [RNA-binding motif]), which are known to regulate alternative splicing of Fas and Bcl-x pre-mRNA transcripts. The structure of the domain consists of an anti-parallel arrangement of six beta strands. Pssm-ID: 465502 Cd Length: 51 Bit Score: 65.73 E-value: 1.22e-14
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| OCRE | cd16074 | OCRE domain; The OCRE (OCtamer REpeat) domain contains 5 repeats of an 8-residue motif, which ... |
129-168 | 2.78e-09 | ||
OCRE domain; The OCRE (OCtamer REpeat) domain contains 5 repeats of an 8-residue motif, which were shown to form beta-strands. Based on the architectures of proteins containing OCRE domains, a role in RNA metabolism and/or signalling has been proposed. Pssm-ID: 293880 Cd Length: 54 Bit Score: 51.52 E-value: 2.78e-09
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| OCRE_SUA_like | cd16166 | OCRE domain found in Suppressor of ABI3-5 (SUA) and similar proteins; SUA is an RNA-binding ... |
131-175 | 5.86e-09 | ||
OCRE domain found in Suppressor of ABI3-5 (SUA) and similar proteins; SUA is an RNA-binding protein located in the nucleus and expressed in all plant tissues. It functions as a splicing factor that influences seed maturation by controlling alternative splicing of ABI3. The suppression of the cryptic ABI3 intron indicates a role of SUA in mRNA processing. SUA also interacts with the prespliceosomal component U2AF65, the larger subunit of the conserved pre-mRNA splicing factor U2AF. SUA contains two RNA recognition motifs surrounding a zinc finger domain, an OCtamer REpeat (OCRE) domain, and a Gly-rich domain close to the C-terminus. Pssm-ID: 293885 Cd Length: 54 Bit Score: 50.76 E-value: 5.86e-09
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| OCRE_RBM6 | cd16163 | OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins; RBM6, also called lung ... |
130-171 | 3.05e-08 | ||
OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins; RBM6, also called lung cancer antigen NY-LU-12, or protein G16, or RNA-binding protein DEF-3, has been predicted to be a nuclear factor based on its nuclear localization signal. It shows high sequence similarity to RNA-binding protein 5 (RBM5 or LUCA15 or NY-REN-9). Both specifically binds poly(G) RNA. RBM6 contain two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), an OCtamer REpeat (OCRE) domain, two C2H2-type zinc fingers, a nuclear localization signal, and a G-patch/D111 domain. In contrast to RBM5, RBM6 has an additional unique domain, the POZ (poxvirus and zinc finger) domain, which may be involved in protein-protein interactions and inhibit binding of target sequences by zinc fingers. Pssm-ID: 293882 [Multi-domain] Cd Length: 57 Bit Score: 48.88 E-value: 3.05e-08
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| OCRE_RBM5_like | cd16162 | OCRE domain found in RNA-binding protein RBM5, RBM10, and similar proteins; RBM5 is a known ... |
127-174 | 7.76e-08 | ||
OCRE domain found in RNA-binding protein RBM5, RBM10, and similar proteins; RBM5 is a known modulator of apoptosis. It may also act as a tumor suppressor or an RNA splicing factor; it specifically binds poly(G) RNA. RBM10, a paralog of RBM5, may play an important role in mRNA generation, processing, and degradation in several cell types. The rat homolog of human RBM10 is protein S1-1, a hypothetical RNA binding protein with poly(G) and poly(U) binding capabilities. Both RBM5 and RBM10, contain two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), an OCtamer REpeat (OCRE) domain, two C2H2-type zinc fingers, and a G-patch/D111 domain. Pssm-ID: 293881 Cd Length: 56 Bit Score: 47.70 E-value: 7.76e-08
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| OCRE | cd16074 | OCRE domain; The OCRE (OCtamer REpeat) domain contains 5 repeats of an 8-residue motif, which ... |
136-166 | 2.42e-07 | ||
OCRE domain; The OCRE (OCtamer REpeat) domain contains 5 repeats of an 8-residue motif, which were shown to form beta-strands. Based on the architectures of proteins containing OCRE domains, a role in RNA metabolism and/or signalling has been proposed. Pssm-ID: 293880 Cd Length: 54 Bit Score: 46.12 E-value: 2.42e-07
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| OCRE_ZOP1_plant | cd16165 | OCRE domain found in Zinc-finger and OCRE domain-containing Protein 1 (ZOP1) and similar ... |
141-166 | 2.27e-05 | ||
OCRE domain found in Zinc-finger and OCRE domain-containing Protein 1 (ZOP1) and similar proteins found in plant; ZOP1 is a novel plant-specific nucleic acid-binding protein required for both RNA-directed DNA methylation (RdDM) and pre-mRNA splicing. It promotes RNA polymerase IV (Pol IV)-dependent siRNA accumulation, DNA methylation, and transcriptional silencing. As a pre-mRNA splicing factor, ZOP1 associates with several typical splicing proteins as well as with RNA polymerase II (RNAP II and Pol II). It also shows both RdDM-dependent and -independent roles in transcriptional silencing. ZOP1 contains an N-terminal C2H2-type ZnF domain and an OCtamer REpeat (OCRE) domain that is usually related to RNA processing. Pssm-ID: 293884 Cd Length: 55 Bit Score: 40.84 E-value: 2.27e-05
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| OCRE_RBM5 | cd16168 | OCRE domain found in RNA-binding protein 5 (RBM5) and similar proteins; RBM5 is also called ... |
129-174 | 4.89e-05 | ||
OCRE domain found in RNA-binding protein 5 (RBM5) and similar proteins; RBM5 is also called protein G15, H37, putative tumor suppressor LUCA15, or renal carcinoma antigen NY-REN-9. It is a known modulator of apoptosis. It acts as a tumor suppressor or an RNA splicing factor. RBM5 shows high sequence similarity to RNA-binding protein 6 (RBM6 or NY-LU-12 or g16 or DEF-3). Both of them specifically binds poly(G) RNA. RBM5 contains two N-terminal RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), an OCtamer REpeat (OCRE) domain, two C2H2-type zinc fingers, a nuclear localization signal, and a G-patch/D111 domain. Pssm-ID: 293887 Cd Length: 56 Bit Score: 40.09 E-value: 4.89e-05
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| OCRE_RBM10 | cd16167 | OCRE domain found in RNA-binding protein 10 (RBM10) and similar proteins; RBM10, also called G ... |
127-174 | 7.75e-05 | ||
OCRE domain found in RNA-binding protein 10 (RBM10) and similar proteins; RBM10, also called G patch domain-containing protein 9, or RNA-binding protein S1-1 (S1-1), is a paralogue of putative tumor suppressor RNA-binding protein 5 (RBM5 or LUCA15 or H37). It may play an important role in mRNA generation, processing and degradation in several cell types. The rat homolog of human RBM10 is protein S1-1, a hypothetical RNA binding protein with poly(G) and poly(U) binding capabilities. RBM10 contains two N-terminal RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), an OCtamer REpeat (OCRE) domain, two C2H2-type zinc fingers, and a G-patch/D111 domain. Pssm-ID: 293886 Cd Length: 64 Bit Score: 39.66 E-value: 7.75e-05
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| OCRE_RBM5 | cd16168 | OCRE domain found in RNA-binding protein 5 (RBM5) and similar proteins; RBM5 is also called ... |
136-166 | 5.15e-04 | ||
OCRE domain found in RNA-binding protein 5 (RBM5) and similar proteins; RBM5 is also called protein G15, H37, putative tumor suppressor LUCA15, or renal carcinoma antigen NY-REN-9. It is a known modulator of apoptosis. It acts as a tumor suppressor or an RNA splicing factor. RBM5 shows high sequence similarity to RNA-binding protein 6 (RBM6 or NY-LU-12 or g16 or DEF-3). Both of them specifically binds poly(G) RNA. RBM5 contains two N-terminal RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), an OCtamer REpeat (OCRE) domain, two C2H2-type zinc fingers, a nuclear localization signal, and a G-patch/D111 domain. Pssm-ID: 293887 Cd Length: 56 Bit Score: 37.01 E-value: 5.15e-04
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| OCRE_ZOP1_plant | cd16165 | OCRE domain found in Zinc-finger and OCRE domain-containing Protein 1 (ZOP1) and similar ... |
125-162 | 2.09e-03 | ||
OCRE domain found in Zinc-finger and OCRE domain-containing Protein 1 (ZOP1) and similar proteins found in plant; ZOP1 is a novel plant-specific nucleic acid-binding protein required for both RNA-directed DNA methylation (RdDM) and pre-mRNA splicing. It promotes RNA polymerase IV (Pol IV)-dependent siRNA accumulation, DNA methylation, and transcriptional silencing. As a pre-mRNA splicing factor, ZOP1 associates with several typical splicing proteins as well as with RNA polymerase II (RNAP II and Pol II). It also shows both RdDM-dependent and -independent roles in transcriptional silencing. ZOP1 contains an N-terminal C2H2-type ZnF domain and an OCtamer REpeat (OCRE) domain that is usually related to RNA processing. Pssm-ID: 293884 Cd Length: 55 Bit Score: 35.44 E-value: 2.09e-03
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| OCRE_RBM6 | cd16163 | OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins; RBM6, also called lung ... |
133-165 | 8.22e-03 | ||
OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins; RBM6, also called lung cancer antigen NY-LU-12, or protein G16, or RNA-binding protein DEF-3, has been predicted to be a nuclear factor based on its nuclear localization signal. It shows high sequence similarity to RNA-binding protein 5 (RBM5 or LUCA15 or NY-REN-9). Both specifically binds poly(G) RNA. RBM6 contain two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), an OCtamer REpeat (OCRE) domain, two C2H2-type zinc fingers, a nuclear localization signal, and a G-patch/D111 domain. In contrast to RBM5, RBM6 has an additional unique domain, the POZ (poxvirus and zinc finger) domain, which may be involved in protein-protein interactions and inhibit binding of target sequences by zinc fingers. Pssm-ID: 293882 [Multi-domain] Cd Length: 57 Bit Score: 33.86 E-value: 8.22e-03
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