NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

786-1025

1.40e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.36 E-value: 1.40e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  786 QLLDALEEARTKHEQIETSIRESCAQDRE-AIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERD-RLQSELRQ 863
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAElAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDiARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  864 RENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKyQNRVNTIEQQYQAdfelwKTEHENKTKLAQAEKENAIRQHYR 943
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEA-EEELEEAEAELAE-----AEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  944 AERDRQLDELVvrmEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQL 1023
Cdd:COG1196   387 ELLEALRAAAE---LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463


                  ..
gi 665399881 1024 EL 1025
Cdd:COG1196   464 LL 465

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

742-1110

2.07e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.09 E-value: 2.07e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   742 RERWVRENTKKIKELTVKGLEAEInkmncdhqrEVTELKRTHQmQLLDALEEARTKHEQIETSIREscAQDREAIIEKER 821
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEK---------ALAELRKELE-ELEEELEQLRKELEELSRQISA--LRKDLARLEAEV 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   822 TAIRERFERQ------LEEEQRTQAEQRQKLTEEFAA---ERDRLQSELRQRENEHQArrqeaLREQEQELEQAKFEMQE 892
Cdd:TIGR02168  743 EQLEERIAQLskelteLEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKA-----LREALDELRAELTLLNE 817

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   893 RMAKQEEKYQNRVNTIEQQYQadfELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVrmeadALQHKEEHELKM 972
Cdd:TIGR02168  818 EAANLRERLESLERRIAATER---RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-----LLNERASLEEAL 889

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   973 NRLKEKYEK---DLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAD 1049
Cdd:TIGR02168  890 ALLRSELEElseELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665399881  1050 IQ----------SELGVLNERHKQEMDQLQKRvHQTIQRQEETIEILKGDndaLRQQCLKLNAVIRQQRKD 1110
Cdd:TIGR02168  970 ARrrlkrlenkiKELGPVNLAAIEEYEELKER-YDFLTAQKEDLTEAKET---LEEAIEEIDREARERFKD 1036

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

713-1009

6.69e-11

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 66.69 E-value: 6.69e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   713 ESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKG-LEAEINKMNCDHQREVT---------ELKRT 782
Cdd:pfam17380  286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAaIYAEQERMAMERERELErirqeerkrELERI 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   783 HQMQL------LDALEEARTKHEQIETSIRESC-AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERD 855
Cdd:pfam17380  366 RQEEIameisrMRELERLQMERQQKNERVRQELeAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   856 RLQSELRQRENEHQaRRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELwKTEHENKTKLAQAEKE 935
Cdd:pfam17380  446 REMERVRLEEQERQ-QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA-MIEEERKRKLLEKEME 523

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 665399881   936 NAIRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNRLKEkyEKDLVLAESVEKSLREKYAETRGKLAEADA 1009
Cdd:pfam17380  524 ERQKAIYEEERRREAEE--ERRKQQEMEERRRIQEQMRKATE--ERSRLEAMEREREMMRQIVESEKARAEYEA 593

PTZ00121

MAEBL; Provisional

657-1031

2.30e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.16 E-value: 2.30e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  657 EKQKSLRAEKSTAAAKLR-DQKKHYEEVVTRHQGFIEQLLKDKGSLCEKvAALTRRLESQNQAWEHRLETELARTKETTM 735
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAKKKaDEAKKAAEAKKKADEAKKAEEAKKADEAKK-AEEAKKADEAKKAEEKKKADELKKAEELKK 1559

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  736 AGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSirescaqdrea 815
Cdd:PTZ00121 1560 AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA----------- 1628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  816 iiEKERTAIRERfeRQLEEEQRTQAEQRQKlteefAAERDRLQSELRQRENEHQARRQEALREQEQElEQAKFEMQERMA 895
Cdd:PTZ00121 1629 --EEEKKKVEQL--KKKEAEEKKKAEELKK-----AEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-EKKAAEALKKEA 1698

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  896 KQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnAIRQHYRAERDRQLDElvvrmEADALQHKEEHELKMNRL 975
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE-AEEDKKKAEEAKKDEE-----EKKKIAHLKKEEEKKAEE 1772

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665399881  976 KEKyEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKM 1031
Cdd:PTZ00121 1773 IRK-EKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEM 1827

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

659-900

6.76e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 6.76e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  659 QKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEhRLETELARTkETTMAGE 738
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA-ALEAELAEL-EKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  739 KIRRERWVRENTKKIKELTVKGLEAEINKMNcdHQREVTELKRThqMQLLDALEEARTkhEQIETsiresCAQDREAIIE 818
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQPPLALLL--SPEDFLDAVRR--LQYLKYLAPARR--EQAEE-----LRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  819 KERTAIRERfeRQLEEEQRTQAEQRQKLTEEfAAERDRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQE 898
Cdd:COG4942   165 LRAELEAER--AELEALLAELEEERAALEAL-KAERQKLLARLEKELAELAAELAE-LQQEAEELEALIARLEAEAAAAA 240


                  ..
gi 665399881  899 EK 900
Cdd:COG4942   241 ER 242

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

625-907

2.80e-05

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 48.21 E-value: 2.80e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   625 QLARRVIALSLRANElaNAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRH----QGFIEQLLKDKGS 700
Cdd:pfam09731  139 SKAESATAVAKEAKD--DAIQAVKAHTDSLKEASDTAEISREKATDSALQKAEALAEKLKEVInlakQSEEEAAPPLLDA 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   701 LCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKirRERWVRENTKKIKELTV------KGLEAEINKMNCDHQR 774
Cdd:pfam09731  217 APETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASE--RIVFQQELVSIFPDIIPvlkednLLSNDDLNSLIAHAHR 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   775 EVTELKRthQMQLLDALEEARtkheqIETSIRESCAQDREAIiEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFaaeR 854
Cdd:pfam09731  295 EIDQLSK--KLAELKKREEKH-----IERALEKQKEELDKLA-EELSARLEEVRAADEAQLRLEFEREREEIRESY---E 363

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 665399881   855 DRLQSELRQRENEHQARRQEALREQEQELE-QAKFEMQERMAKQEEKYQNRVNT 907
Cdd:pfam09731  364 EKLRTELERQAEAHEEHLKDVLVEQEIELQrEFLQDIKEKVEEERAGRLLKLNE 417

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

958-1109

7.14e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 7.14e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  958 EADALQHK-EEHELKMNRLKEKYekDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDI- 1035
Cdd:COG3206   183 QLPELRKElEEAEAALEEFRQKN--GLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELl 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881 1036 ----IMERDRLRDNLNADIQSELGVLNERH------KQEMDQLQKRVHQTIQRQEETIEIlkgDNDALRQQCLKLNAVIR 1105
Cdd:COG3206   261 qspvIQQLRAQLAELEAELAELSARYTPNHpdvialRAQIAALRAQLQQEAQRILASLEA---ELEALQAREASLQAQLA 337


                  ....
gi 665399881 1106 QQRK 1109
Cdd:COG3206   338 QLEA 341

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

785-897

1.98e-04

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 44.49 E-value: 1.98e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  785 MQLLDALEEA--RTKHEQIETSIRESCAQDREAIIEKERTAIRERF---ERQLEEEQRTQAEQRQKLTEEFAAERDRLQS 859
Cdd:cd16269   176 LQSKEAEAEAilQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQrelEQKLEDQERSYEEHLRQLKEKMEEERENLLK 255

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 665399881  860 ELrQRENEHQarrqeaLREQEQELEQAKFEMQERMAKQ 897
Cdd:cd16269   256 EQ-ERALESK------LKEQEALLEEGFKEQAELLQEE 286

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

625-916

2.83e-04

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.05 E-value: 2.83e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   625 QLARRVIALSLRANELANAIHMSKEHVFQLRG---------EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLL 695
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEelaeaeaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   696 KDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRrerwvrENTKKIKELT--VKGLEAEINKMNCDHQ 773
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE------ELESELEALLneRASLEEALALLRSELE 897

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   774 REVTELK--RTHQMQLLDALEEARTKHEQIETsirescaqdREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFA 851
Cdd:TIGR02168  898 ELSEELRelESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665399881   852 AERDRLqSELRQR-------------ENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADF 916
Cdd:TIGR02168  969 EARRRL-KRLENKikelgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQVNENF 1045

growth_prot_Scy

NF041483

polarized growth protein Scy;

709-1021

5.25e-04

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 44.43 E-value: 5.25e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  709 TRRLESQNQAWEHRLETELARTkETTMAGEKIRRERwVRENTKKIKE--------LTVKGLEAE--INKMNCDHQR---E 775
Cdd:NF041483  433 AKTVELQEEARRLRGEAEQLRA-EAVAEGERIRGEA-RREAVQQIEEaartaeelLTKAKADADelRSTATAESERvrtE 510

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  776 VTELKRTHQMQLLDALEEARTKHEQIETsirESCAQDREAIIEKERTAirerfeRQLEEEQRTQAEQRQkltEEFAAERD 855
Cdd:NF041483  511 AIERATTLRRQAEETLERTRAEAERLRA---EAEEQAEEVRAAAERAA------RELREETERAIAARQ---AEAAEELT 578

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  856 RLQSELRQRenehQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKE 935
Cdd:NF041483  579 RLHTEAEER----LTAAEEALADARAEAERIRREAAEETERLRTEAAERIRTLQAQAEQEAERLRTEAAADASAARAEGE 654

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  936 NA---IRQHYRAERDRQLDELV-----VRMEADALQHK--EEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGK-- 1003
Cdd:NF041483  655 NVavrLRSEAAAEAERLKSEAQesadrVRAEAAAAAERvgTEAAEALAAAQEEAARRRREAEETLGSARAEADQERERar 734

                         330       340
                  ....*....|....*....|....
gi 665399881 1004 ------LAEADAQVRNSQAEVKQL 1021
Cdd:NF041483  735 eqseelLASARKRVEEAQAEAQRL 758

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

903-1083

9.28e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 43.67 E-value: 9.28e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  903 NRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA--IRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNrlkEKYE 980
Cdd:NF012221 1533 NVVATSESSQQADAVSKHAKQDDAAQNALADKERAeaDRQRLEQEKQQQLAA--ISGSQSQLESTDQNALETN---GQAQ 1607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  981 KDLVLAES--VEKSLREK---------YAETRGklaEADAQVRNSQAE--VKQLQLELSHSKKMCGDIIME-RDRLRDNL 1046
Cdd:NF012221 1608 RDAILEESraVTKELTTLaqgldaldsQATYAG---ESGDQWRNPFAGglLDRVQEQLDDAKKISGKQLADaKQRHVDNQ 1684

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 665399881 1047 ----NADIQSELGVLN-ERHKQEMDQ-LQKRVHQTIQRQEETI 1083
Cdd:NF012221 1685 qkvkDAVAKSEAGVAQgEQNQANAEQdIDDAKADAEKRKDDAL 1727

PRK11281

mechanosensitive channel MscK;

955-1109

6.69e-03

mechanosensitive channel MscK;

Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 40.67 E-value: 6.69e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  955 VRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSlREKYAETRGKLAEADAQVRNSQAEVKQLqlelshsKKMCGD 1034
Cdd:PRK11281   41 VQAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQ-KEETEQLKQQLAQAPAKLRQAQAELEAL-------KDDNDE 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881 1035 IIMER------DRLRDNLN------ADIQSELGVLN----------ERHKQEMDQLQKRVhQTIQRQEETIEILKGDNDA 1092
Cdd:PRK11281  113 ETRETlstlslRQLESRLAqtldqlQNAQNDLAEYNsqlvslqtqpERAQAALYANSQRL-QQIRNLLKGGKVGGKALRP 191

                         170       180
                  ....*....|....*....|..
gi 665399881 1093 LRQQCLK-----LNAVIRQQRK 1109
Cdd:PRK11281  192 SQRVLLQaeqalLNAQNDLQRK 213

Name

Accession

Description

Interval

E-value

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

786-1025

1.40e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.36 E-value: 1.40e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  786 QLLDALEEARTKHEQIETSIRESCAQDRE-AIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERD-RLQSELRQ 863
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAElAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDiARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  864 RENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKyQNRVNTIEQQYQAdfelwKTEHENKTKLAQAEKENAIRQHYR 943
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEA-EEELEEAEAELAE-----AEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  944 AERDRQLDELVvrmEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQL 1023
Cdd:COG1196   387 ELLEALRAAAE---LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463


                  ..
gi 665399881 1024 EL 1025
Cdd:COG1196   464 LL 465

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

657-989

2.07e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.97 E-value: 2.07e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  657 EKQ-KSLRAEKSTA--AAKLRDQKKHYEEVVTRHQgfIEQLLKDKGSLCEKVAALTRRLESQnQAWEHRLETELARTKEt 733
Cdd:COG1196   199 ERQlEPLERQAEKAerYRELKEELKELEAELLLLK--LRELEAELEELEAELEELEAELEEL-EAELAELEAELEELRL- 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  734 tmageKIRRERwvrentKKIKELtvKGLEAEINKmncdhQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDR 813
Cdd:COG1196   275 -----ELEELE------LELEEA--QAEEYELLA-----ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  814 EAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQaRRQEALREQEQELEQAKFEMQER 893
Cdd:COG1196   337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL-RAAAELAAQLEELEEAEEALLER 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  894 MAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRmEADALQHKEEHELKMN 973
Cdd:COG1196   416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA-LAELLEELAEAAARLL 494

                         330
                  ....*....|....*.
gi 665399881  974 RLKEKYEKDLVLAESV 989
Cdd:COG1196   495 LLLEAEADYEGFLEGV 510

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

742-1110

2.07e-13

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.09 E-value: 2.07e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   742 RERWVRENTKKIKELTVKGLEAEInkmncdhqrEVTELKRTHQmQLLDALEEARTKHEQIETSIREscAQDREAIIEKER 821
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEK---------ALAELRKELE-ELEEELEQLRKELEELSRQISA--LRKDLARLEAEV 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   822 TAIRERFERQ------LEEEQRTQAEQRQKLTEEFAA---ERDRLQSELRQRENEHQArrqeaLREQEQELEQAKFEMQE 892
Cdd:TIGR02168  743 EQLEERIAQLskelteLEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKA-----LREALDELRAELTLLNE 817

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   893 RMAKQEEKYQNRVNTIEQQYQadfELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVrmeadALQHKEEHELKM 972
Cdd:TIGR02168  818 EAANLRERLESLERRIAATER---RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-----LLNERASLEEAL 889

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   973 NRLKEKYEK---DLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAD 1049
Cdd:TIGR02168  890 ALLRSELEElseELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665399881  1050 IQ----------SELGVLNERHKQEMDQLQKRvHQTIQRQEETIEILKGDndaLRQQCLKLNAVIRQQRKD 1110
Cdd:TIGR02168  970 ARrrlkrlenkiKELGPVNLAAIEEYEELKER-YDFLTAQKEDLTEAKET---LEEAIEEIDREARERFKD 1036

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

653-1027

2.67e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.59 E-value: 2.67e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  653 QLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKE 732
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  733 -TTMAGEKIRRERWVRENTKKIKELTVKGLEAEinkmncDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIREScAQ 811
Cdd:COG1196   297 lARLEQDIARLEERRRELEERLEELEEELAELE------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL-LE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  812 DREAIIEKERTaiRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENehQARRQEALREQEQELEQAKFEMQ 891
Cdd:COG1196   370 AEAELAEAEEE--LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE--LEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  892 ERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKenairqhyRAERDRQLDELVVRMEADALQHKEEHELK 971
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--------AAARLLLLLEAEADYEGFLEGVKAALLLA 517

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665399881  972 MNRLKEKYEKDLVLAESVEkslrEKYAETRGKLAEADAQVRNSQAEVKQLQLELSH 1027
Cdd:COG1196   518 GLRGLAGAVAVLIGVEAAY----EAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

777-1108

5.75e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 70.35 E-value: 5.75e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  777 TELKRTHQMQLLDALEEARTKHEQIETSIREscaqdreaiiekeRTAIRERFERQLEEEQRTQAEQRQKLTEEfAAERDR 856
Cdd:COG1196   220 EELKELEAELLLLKLRELEAELEELEAELEE-------------LEAELEELEAELAELEAELEELRLELEEL-ELELEE 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  857 LQSELRQRENEHQA--RRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEK 934
Cdd:COG1196   286 AQAEEYELLAELARleQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  935 ENAIRQHYRAERDRQLDELVVRmEADALQHKEEHELKMNRLKEkyekdlvlAESVEKSLREKYAETRGKLAEADAQVRNS 1014
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEE-LLEALRAAAELAAQLEELEE--------AEEALLERLERLEEELEELEEALAELEEE 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881 1015 QAEVKQLQLELSHSKKmcgdiimERDRLRDNLNADIQSELGVLNERHKQEMDQLQKRvhQTIQRQEETIEILKGDNDALR 1094
Cdd:COG1196   437 EEEEEEALEEAAEEEA-------ELEEEEEALLELLAELLEEAALLEAALAELLEEL--AEAAARLLLLLEAEADYEGFL 507

                         330
                  ....*....|....
gi 665399881 1095 QQCLKLNAVIRQQR 1108
Cdd:COG1196   508 EGVKAALLLAGLRG 521

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

713-1009

6.69e-11

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 66.69 E-value: 6.69e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   713 ESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKG-LEAEINKMNCDHQREVT---------ELKRT 782
Cdd:pfam17380  286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAaIYAEQERMAMERERELErirqeerkrELERI 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   783 HQMQL------LDALEEARTKHEQIETSIRESC-AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERD 855
Cdd:pfam17380  366 RQEEIameisrMRELERLQMERQQKNERVRQELeAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   856 RLQSELRQRENEHQaRRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELwKTEHENKTKLAQAEKE 935
Cdd:pfam17380  446 REMERVRLEEQERQ-QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA-MIEEERKRKLLEKEME 523

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 665399881   936 NAIRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNRLKEkyEKDLVLAESVEKSLREKYAETRGKLAEADA 1009
Cdd:pfam17380  524 ERQKAIYEEERRREAEE--ERRKQQEMEERRRIQEQMRKATE--ERSRLEAMEREREMMRQIVESEKARAEYEA 593

PTZ00121

MAEBL; Provisional

657-1031

2.30e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.16 E-value: 2.30e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  657 EKQKSLRAEKSTAAAKLR-DQKKHYEEVVTRHQGFIEQLLKDKGSLCEKvAALTRRLESQNQAWEHRLETELARTKETTM 735
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAKKKaDEAKKAAEAKKKADEAKKAEEAKKADEAKK-AEEAKKADEAKKAEEKKKADELKKAEELKK 1559

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  736 AGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSirescaqdrea 815
Cdd:PTZ00121 1560 AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA----------- 1628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  816 iiEKERTAIRERfeRQLEEEQRTQAEQRQKlteefAAERDRLQSELRQRENEHQARRQEALREQEQElEQAKFEMQERMA 895
Cdd:PTZ00121 1629 --EEEKKKVEQL--KKKEAEEKKKAEELKK-----AEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-EKKAAEALKKEA 1698

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  896 KQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnAIRQHYRAERDRQLDElvvrmEADALQHKEEHELKMNRL 975
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE-AEEDKKKAEEAKKDEE-----EKKKIAHLKKEEEKKAEE 1772

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665399881  976 KEKyEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKM 1031
Cdd:PTZ00121 1773 IRK-EKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEM 1827

mukB

chromosome partition protein MukB;

774-1109

3.68e-10

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 64.59 E-value: 3.68e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  774 REVTELKRTHQmqlldALEEARTKHEQIetsireSCAQDREAIIEKERTAIRERfERQLE--EEQRTQAEQRQKLTEEFA 851
Cdd:PRK04863  807 FDVQKLQRLHQ-----AFSRFIGSHLAV------AFEADPEAELRQLNRRRVEL-ERALAdhESQEQQQRSQLEQAKEGL 874

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  852 AERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQermakqeeKYQNRVNTIEQQY------QADFELWKTEHEn 925
Cdd:PRK04863  875 SALNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRFVQ--------QHGNALAQLEPIVsvlqsdPEQFEQLKQDYQ- 945

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  926 ktklaQAEKenaiRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKyekdlvlaesveksLREKYAETRGKLA 1005
Cdd:PRK04863  946 -----QAQQ----TQRDAKQQAFALTEVVQRRAHFSYEDAAEMLAKNSDLNEK--------------LRQRLEQAEQERT 1002

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881 1006 EADAQVRNSQAEVKQlqlelshSKKMCGDIIMERDRLRDNLNADIQ--SELGV-----LNERHKQEMDQLQKRVHQTIQR 1078
Cdd:PRK04863 1003 RAREQLRQAQAQLAQ-------YNQVLASLKSSYDAKRQMLQELKQelQDLGVpadsgAEERARARRDELHARLSANRSR 1075

                         330       340       350
                  ....*....|....*....|....*....|....
gi 665399881 1079 Q---EETIEILKGDNDALRQQCLKLNAVIRQQRK 1109
Cdd:PRK04863 1076 RnqlEKQLTFCEAEMDNLTKKLRKLERDYHEMRE 1109

PTZ00121

MAEBL; Provisional

636-1070

5.05e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.01 E-value: 5.05e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  636 RANELANAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEV--VTRHQGFIEQLLKDKGSLCEKVAALTRRLE 713
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKkkADEAKKKAEEDKKKADELKKAAAAKKKADE 1422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  714 SQNQAWEHRLETELARTKETTMAGEKIRRERwvrENTKKIKELTVKGLE---AEINKMNCDHQREVTELKRTHQMQLLDA 790
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKKADEAKKKA---EEAKKAEEAKKKAEEakkADEAKKKAEEAKKADEAKKKAEEAKKKA 1499

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  791 lEEARTKHEQIETSIRESCAQD-REAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQ 869
Cdd:PTZ00121 1500 -DEAKKAAEAKKKADEAKKAEEaKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNM 1578

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  870 A-RRQEALREQEQ----------------ELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADF--------ELWKTEHE 924
Cdd:PTZ00121 1579 AlRKAEEAKKAEEarieevmklyeeekkmKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEaeekkkaeELKKAEEE 1658

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  925 NKTKLAQaEKENAIRQHYRAERDRQLDElVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKL 1004
Cdd:PTZ00121 1659 NKIKAAE-EAKKAEEDKKKAEEAKKAEE-DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAK 1736

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665399881 1005 AEADAQVRNSQaEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSELGVLNERHKQEMDQLQK 1070
Cdd:PTZ00121 1737 KEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

811-1093

2.10e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 62.01 E-value: 2.10e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   811 QDREAIIEKERTAIRERFER--QLEEEQRTQAEQRQKLTEEFAAERDRLQSElRQRENEHQARRQEALREQEQELEQAKF 888
Cdd:TIGR02169  680 RERLEGLKRELSSLQSELRRieNRLDELSQELSDASRKIGEIEKEIEQLEQE-EEKLKERLEELEEDLSSLEQEIENVKS 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   889 EMQE---RMAKQEE---KYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDElvvRMEADAL 962
Cdd:TIGR02169  759 ELKEleaRIEELEEdlhKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK---EYLEKEI 835

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   963 QHKEEhelKMNRLKEKyekdlvlaesvEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKmcgdiimERDRL 1042
Cdd:TIGR02169  836 QELQE---QRIDLKEQ-----------IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK-------ERDEL 894

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 665399881  1043 rdnlnadiQSELGVLNERHKQEMDQLQKRVHQtIQRQEETIEILKGDNDAL 1093
Cdd:TIGR02169  895 --------EAQLRELERKIEELEAQIEKKRKR-LSELKAKLEALEEELSEI 936

PTZ00121

MAEBL; Provisional

647-1006

2.39e-09

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.08 E-value: 2.39e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  647 SKEHVFQLRGEKQKSL-----RAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLceKVAALTRRLESQNQAWEH 721
Cdd:PTZ00121 1062 AKAHVGQDEGLKPSYKdfdfdAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAK--KKAEDARKAEEARKAEDA 1139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  722 R-----------------------LETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTE 778
Cdd:PTZ00121 1140 RkaeearkaedakrveiarkaedaRKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARK 1219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  779 LKRTHQMQLLDALEEARTKHEqietsirESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQ 858
Cdd:PTZ00121 1220 AEDAKKAEAVKKAEEAKKDAE-------EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA 1292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  859 SELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNrvntIEQQYQADfELWKTEHENKTKLAQAEKENAI 938
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAA-EAAKAEAEAAADEAEAAEEKAE 1367

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665399881  939 RQHYRAERDRQldelvvrmEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLRE-KYAETRGKLAE 1006
Cdd:PTZ00121 1368 AAEKKKEEAKK--------KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAkKKADEAKKKAE 1428

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

812-1109

9.01e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 59.97 E-value: 9.01e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  812 DREAIIEKERTAIRErFERQLEEEQRTQAEQRQKLTEefAAER----DRLQSELRQRENEHQARRQEALREQEQELEQAK 887
Cdd:COG3096   833 DPEAELAALRQRRSE-LERELAQHRAQEQQLRQQLDQ--LKEQlqllNKLLPQANLLADETLADRLEELREELDAAQEAQ 909

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  888 FEMQeRMAKQEEKYQNRVNTIeQQYQADFELWKTEHENktklAQAEKENAIRQHYraerdrQLDELVVRMEADALQHKEE 967
Cdd:COG3096   910 AFIQ-QHGKALAQLEPLVAVL-QSDPEQFEQLQADYLQ----AKEQQRRLKQQIF------ALSEVVQRRPHFSYEDAVG 977

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  968 HELKMNRLKEKYEKDLVLAESvekslrekyaetrgKLAEADAQVRNSQAEVKQLQLELSHSKKmcgdiimERDRLRDNLN 1047
Cdd:COG3096   978 LLGENSDLNEKLRARLEQAEE--------------ARREAREQLRQAQAQYSQYNQVLASLKS-------SRDAKQQTLQ 1036

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 665399881 1048 ADIQ--SELGVLN-----ERHKQEMDQLQKRVHQTIQRQ---EETIEILKGDNDALRQQCLKLNAVIRQQRK 1109
Cdd:COG3096  1037 ELEQelEELGVQAdaeaeERARIRRDELHEELSQNRSRRsqlEKQLTRCEAEMDSLQKRLRKAERDYKQERE 1108

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

751-1020

1.76e-08

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 57.62 E-value: 1.76e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   751 KKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETsiRESCAQDREAIIEKERTAIRERFER 830
Cdd:pfam13868   32 KRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEE--REQKRQEEYEEKLQEREQMDEIVER 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   831 QLEEEQRTQAEQRQKLTE------EFAAERDRLQSELRQRENE----------HQARRQEALREQEQELEQAKFEMQERM 894
Cdd:pfam13868  110 IQEEDQAEAEEKLEKQRQlreeidEFNEEQAEWKELEKEEEREederileylkEKAEREEEREAEREEIEEEKEREIARL 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   895 AKQEEKYQNRvntIEQQYQADFELWKTEHENKTK---LAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHELK 971
Cdd:pfam13868  190 RAQQEKAQDE---KAERDELRAKLYQEEQERKERqkeREEAEKKARQRQELQQAREEQIELKERRLAEEAEREEEEFERM 266

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 665399881   972 MNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQ 1020
Cdd:pfam13868  267 LRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELE 315

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

671-1077

2.31e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.24 E-value: 2.31e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  671 AKLRDQKKHYEEVVTRHQGfIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKettmAGEKIRRERWVRENT 750
Cdd:COG4717    81 KEAEEKEEEYAELQEELEE-LEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAE----LAELPERLEELEERL 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  751 KKIKEL--TVKGLEAEINKmncdHQREVTELKRTHQMQLLDALEEARTKHEQIETSIREscAQDREAIIEKERTAIRERF 828
Cdd:COG4717   156 EELRELeeELEELEAELAE----LQEELEELLEQLSLATEEELQDLAEELEELQQRLAE--LEEELEEAQEELEELEEEL 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  829 ErQLEEEQRTQAEQRQKLTEE-----------FAAERDRLQSELRQREN-------------EHQARRQEALREQEQELE 884
Cdd:COG4717   230 E-QLENELEAAALEERLKEARlllliaaallaLLGLGGSLLSLILTIAGvlflvlgllallfLLLAREKASLGKEAEELQ 308

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  885 QAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEN--AIRQHYRAERDRQLDELVVRMEAD-- 960
Cdd:COG4717   309 ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEeeLQLEELEQEIAALLAEAGVEDEEElr 388

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  961 --ALQHKEEHELK--MNRLKEKYEKDL-----VLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHskkm 1031
Cdd:COG4717   389 aaLEQAEEYQELKeeLEELEEQLEELLgeleeLLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQ---- 464

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 665399881 1032 cgdiiMERDRLRDNLNADIQSELGVLNERHKQE---------MDQLQKRVHQTIQ 1077
Cdd:COG4717   465 -----LEEDGELAELLQELEELKAELRELAEEWaalklalelLEEAREEYREERL 514

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

823-1025

3.51e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.47 E-value: 3.51e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  823 AIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHqarrqEALREQEQELEQAKfEMQERMAKQEEKYQ 902
Cdd:COG4717    42 FIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKE-----EEYAELQEELEELE-EELEELEAELEELR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  903 NRVNTIEQQYQAdFELWKTEHENKTKLAQAEKE-NAIRQHY--RAERDRQLDELvvrmEADALQHKEEHELKMNRLKEKY 979
Cdd:COG4717   116 EELEKLEKLLQL-LPLYQELEALEAELAELPERlEELEERLeeLRELEEELEEL----EAELAELQEELEELLEQLSLAT 190

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 665399881  980 EKDLvlaesveKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLEL 1025
Cdd:COG4717   191 EEEL-------QDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

803-1109

4.18e-08

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.77 E-value: 4.18e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   803 TSIRESCAQDREAIIEkeRTAIRERFERQLEEEQRTQAEQRQKLteefaAERDRLQSELRQRENEHQARRQEALREQEQE 882
Cdd:TIGR02169  145 TDFISMSPVERRKIID--EIAGVAEFDRKKEKALEELEEVEENI-----ERLDLIIDEKRQQLERLRREREKAERYQALL 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   883 LEQAKFEMQER------MAKQEEKYQNRVNTIEQQyQADF-----ELWKTEHENKTKLAQAEKE---------NAIR--- 939
Cdd:TIGR02169  218 KEKREYEGYELlkekeaLERQKEAIERQLASLEEE-LEKLteeisELEKRLEEIEQLLEELNKKikdlgeeeqLRVKeki 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   940 ---QHYRAERDRQLDELVVRME-ADALQHKEEHEL-----KMNRLKEKYEKDLVLAESVE---KSLREKYAETRGKLAEA 1007
Cdd:TIGR02169  297 gelEAEIASLERSIAEKERELEdAEERLAKLEAEIdkllaEIEELEREIEEERKRRDKLTeeyAELKEELEDLRAELEEV 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  1008 DAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLN------ADIQSELGVLNERHKQ---EMDQLQKRVHQTIQR 1078
Cdd:TIGR02169  377 DKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQrlseelADLNAAIAGIEAKINEleeEKEDKALEIKKQEWK 456

                          330       340       350
                   ....*....|....*....|....*....|.
gi 665399881  1079 QEETIEILKGDNDALRQQCLKLNAVIRQQRK 1109
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSK 487

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

632-968

4.61e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 57.65 E-value: 4.61e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  632 ALSLRANELANAIHMSKEHvfQLRGEKQKSLRAEKSTAAAklrdqkkHYEEVVT--RHQGFIEQLLKDkgslcekVAALT 709
Cdd:COG3096   297 ARRQLAEEQYRLVEMAREL--EELSARESDLEQDYQAASD-------HLNLVQTalRQQEKIERYQED-------LEELT 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  710 RRLESQNQAWEHRLEtELARTKETTMAGEKirrerwvrentkkikelTVKGLEAEInkmnCDHQREVTELK-RTHQ-MQL 787
Cdd:COG3096   361 ERLEEQEEVVEEAAE-QLAEAEARLEAAEE-----------------EVDSLKSQL----ADYQQALDVQQtRAIQyQQA 418

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  788 LDALEEARTKHEQIETSIrESCAQDREAIIEKERTAIRERFE-RQ---LEEEQRTQAEQRQKLTEEFAAERDRLQSELRQ 863
Cdd:COG3096   419 VQALEKARALCGLPDLTP-ENAEDYLAAFRAKEQQATEEVLElEQklsVADAARRQFEKAYELVCKIAGEVERSQAWQTA 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  864 RENEHQARRQEALREQEQELEQAKFEMQERMAKQE--EKYQNRVN-TIEQQYQA--DFELWKTEHENKTKLAQAEKENAI 938
Cdd:COG3096   498 RELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQnaERLLEEFCqRIGQQLDAaeELEELLAELEAQLEELEEQAAEAV 577

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 665399881  939 RQhyRAERDRQLDELVVRME------------ADALQHKEEH 968
Cdd:COG3096   578 EQ--RSELRQQLEQLRARIKelaarapawlaaQDALERLREQ 617

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

786-1095

6.34e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 57.06 E-value: 6.34e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   786 QLLDALEEARTKHEQIETSIRESCAQDREAIiEKERTAIRERFERQLEE-EQRTQAE---------QRQKLTEEFAAERD 855
Cdd:pfam17380  273 QLLHIVQHQKAVSERQQQEKFEKMEQERLRQ-EKEEKAREVERRRKLEEaEKARQAEmdrqaaiyaEQERMAMERERELE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   856 RLQSELRQRENEhQARRQEALREQEQ--ELEQAKFEMQER--MAKQEEKYQNRVNTIEQQYQADFELWKTEHENktklAQ 931
Cdd:pfam17380  352 RIRQEERKRELE-RIRQEEIAMEISRmrELERLQMERQQKneRVRQELEAARKVKILEEERQRKIQQQKVEMEQ----IR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   932 AEKENAIRQHYR---AERDRQLDElvVRMEadalQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEAD 1008
Cdd:pfam17380  427 AEQEEARQREVRrleEERAREMER--VRLE----EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKE 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  1009 AQVRnsqaevKQLQLELSHSKKMCGDIIMErdrlRDNLNADIQSELGVLNERHKQEMDQLQKRVHQTIQRQEET---IEI 1085
Cdd:pfam17380  501 LEER------KQAMIEEERKRKLLEKEMEE----RQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEErsrLEA 570

                          330
                   ....*....|
gi 665399881  1086 LKGDNDALRQ 1095
Cdd:pfam17380  571 MEREREMMRQ 580

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

810-1110

6.74e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.87 E-value: 6.74e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  810 AQDREAIIE--------KERtaiRERFERQLEEeqrtqAEQR----QKLTEEFAAERDRLQselRQREnehQARRQEALR 877
Cdd:COG1196   154 PEERRAIIEeaagiskyKER---KEEAERKLEA-----TEENlerlEDILGELERQLEPLE---RQAE---KAERYRELK 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  878 EqeqELEQAKFEM--------QERMAKQEEKYQNRVNTIEQQyQADFELWKTEHEnKTKLAQAEKENAIRQhyRAERDRQ 949
Cdd:COG1196   220 E---ELKELEAELlllklrelEAELEELEAELEELEAELEEL-EAELAELEAELE-ELRLELEELELELEE--AQAEEYE 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  950 LDELVVRMEADaLQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSK 1029
Cdd:COG1196   293 LLAELARLEQD-IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881 1030 KMCGDIIMERDRLRDNLNADIQSELGVLNERhkQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNAVIRQQRK 1109
Cdd:COG1196   372 AELAEAEEELEELAEELLEALRAAAELAAQL--EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449


                  .
gi 665399881 1110 D 1110
Cdd:COG1196   450 E 450

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

657-914

2.73e-07

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.06 E-value: 2.73e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   657 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRhQGFIEQLLKDKGSLCEKVAALTRRLESQNQAwEHRLETELARTKEttma 736
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQEL-EEKLEELRLEVSELEEEIEELQKELYALANE-ISRLEQQKQILRE---- 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   737 gekiRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIREscaqdREAI 816
Cdd:TIGR02168  310 ----RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE-----LEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   817 IEKERTAIRERfERQLEEEQRTQAEQRQKLtEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQ---ER 893
Cdd:TIGR02168  381 LETLRSKVAQL-ELQIASLNNEIERLEARL-ERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQeelER 458

                          250       260
                   ....*....|....*....|.
gi 665399881   894 MAKQEEKYQNRVNTIEQQYQA 914
Cdd:TIGR02168  459 LEEALEELREELEEAEQALDA 479

PTZ00121

MAEBL; Provisional

657-1081

2.86e-07

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.15 E-value: 2.86e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  657 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTrhqgfIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMA 736
Cdd:PTZ00121 1288 EKKKADEAKKAEEKKKADEAKKKAEEAKK-----ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA 1362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  737 GEKIRRERWVRENTKKikeltvkglEAEINKMNCDHQREVTELKRThqmqlldaLEEARTKHEQIETSIRESCAQDrEAI 816
Cdd:PTZ00121 1363 EEKAEAAEKKKEEAKK---------KADAAKKKAEEKKKADEAKKK--------AEEDKKKADELKKAAAAKKKAD-EAK 1424

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  817 IEKERTAIRERFERQLEEEQRTQaEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQE--QELEQAKFEMQE-R 893
Cdd:PTZ00121 1425 KKAEEKKKADEAKKKAEEAKKAD-EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEakKKAEEAKKKADEaK 1503

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  894 MAKQEEKYQNRVNTIEQQYQADfELWKTEHENKtklaqAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHELKMN 973
Cdd:PTZ00121 1504 KAAEAKKKADEAKKAEEAKKAD-EAKKAEEAKK-----ADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKN 1577

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  974 RLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSE 1053
Cdd:PTZ00121 1578 MALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE 1657

                         410       420
                  ....*....|....*....|....*...
gi 665399881 1054 LGVLNERHKQEMDQLQKRVHQTIQRQEE 1081
Cdd:PTZ00121 1658 ENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685

mukB

chromosome partition protein MukB;

632-978

6.33e-07

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 53.81 E-value: 6.33e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  632 ALSLRAnELANA---IHMSKEHVFQLRGEKQKSLRAEKSTAAAkLRDQKKHYEEVVT--RHQGFIEQLLKDkgslcekVA 706
Cdd:PRK04863  288 ALELRR-ELYTSrrqLAAEQYRLVEMARELAELNEAESDLEQD-YQAASDHLNLVQTalRQQEKIERYQAD-------LE 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  707 ALTRRLESQNQAWEHRLETELARTKETTMAGEKIRR---------ERWVRENTKKIK------------------ELTVK 759
Cdd:PRK04863  359 ELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDElksqladyqQALDVQQTRAIQyqqavqalerakqlcglpDLTAD 438

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  760 GLEAEINKMNcDHQREVTElKRTHQMQLLDALEEARTKHEQIETSI----------------RESCAQDREAIIEKERT- 822
Cdd:PRK04863  439 NAEDWLEEFQ-AKEQEATE-ELLSLEQKLSVAQAAHSQFEQAYQLVrkiagevsrseawdvaRELLRRLREQRHLAEQLq 516

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  823 AIRERF---ERQLEEEQR-----TQAEQRQKLTEEFAAERDRLQSELRQRENEHQArRQEALREQ----EQELEQAKFEM 890
Cdd:PRK04863  517 QLRMRLselEQRLRQQQRaerllAEFCKRLGKNLDDEDELEQLQEELEARLESLSE-SVSEARERrmalRQQLEQLQARI 595

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  891 QERMAKQEE--KYQNRVNTIEQQYQADFElwKTEHENKTKLAQAEKENAIRQHYR--AERDRQLDElvvrmEADALQHKE 966
Cdd:PRK04863  596 QRLAARAPAwlAAQDALARLREQSGEEFE--DSQDVTEYMQQLLERERELTVERDelAARKQALDE-----EIERLSQPG 668

                         410
                  ....*....|...
gi 665399881  967 EHEL-KMNRLKEK 978
Cdd:PRK04863  669 GSEDpRLNALAER 681

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

703-1030

7.33e-07

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 7.33e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   703 EKVAALTRRLEsQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKEL--TVKGLEAEINKMNcdhqREVTELK 780
Cdd:TIGR02169  211 ERYQALLKEKR-EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELekRLEEIEQLLEELN----KKIKDLG 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   781 RTHQMQLLDALEEARTKHEQIETSIRESC-----AQDREAIIEKERTAIRERFErQLEEEQRTQAeqrqklteefaAERD 855
Cdd:TIGR02169  286 EEEQLRVKEKIGELEAEIASLERSIAEKEreledAEERLAKLEAEIDKLLAEIE-ELEREIEEER-----------KRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   856 RLQSELRQRENEHQARRQEAlreqeqeleqakfemqermakqeekyqnrvntieQQYQADFELWKTEHenktKLAQAEKE 935
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAEL----------------------------------EEVDKEFAETRDEL----KDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   936 NAIRQHY--RAERDRQLDELvVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSlREKYAETRGKLAEADAQVRN 1013
Cdd:TIGR02169  396 KLKREINelKRELDRLQEEL-QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ-EWKLEQLAADLSKYEQELYD 473

                          330
                   ....*....|....*..
gi 665399881  1014 SQAEVKQLQLELSHSKK 1030
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQR 490

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

669-1110

7.89e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.38 E-value: 7.89e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  669 AAAKLRDQKKHYEEVVTRHQGFIEQLLKdkgslcekvAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRE 748
Cdd:COG4913   243 ALEDAREQIELLEPIRELAERYAAARER---------LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELER 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  749 NTKKIKELTVKGLEAEINKMNCDHQReVTELKRthqmqLLDALEEARTKHEQIETSIRESCAQdreaiIEKERTAIRERF 828
Cdd:COG4913   314 LEARLDALREELDELEAQIRGNGGDR-LEQLER-----EIERLERELEERERRRARLEALLAA-----LGLPLPASAEEF 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  829 ERQLEEEQRtQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQE--ALREQ----EQELEQAKFEMQER--------- 893
Cdd:COG4913   383 AALRAEAAA-LLEALEEELEALEEALAEAEAALRDLRRELRELEAEiaSLERRksniPARLLALRDALAEAlgldeaelp 461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  894 -------MAKQEEKYQNRVNT----------IEQQYQADFelwkTEHENKTKLAQaekenaiRQHYRAERDRQLDELVVR 956
Cdd:COG4913   462 fvgelieVRPEEERWRGAIERvlggfaltllVPPEHYAAA----LRWVNRLHLRG-------RLVYERVRTGLPDPERPR 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  957 MEADALQHK---EEHELKmNRLKEKYEK--DLVLAESVEKSLREKYAETR-------GKLAEADAQVRNS---------- 1014
Cdd:COG4913   531 LDPDSLAGKldfKPHPFR-AWLEAELGRrfDYVCVDSPEELRRHPRAITRagqvkgnGTRHEKDDRRRIRsryvlgfdnr 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881 1015 ------QAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAdiqseLGVLNERHKQEMDQLQkrVHQTIQRQEETIEILKG 1088
Cdd:COG4913   610 aklaalEAELAELEEELAEAEERLEALEAELDALQERREA-----LQRLAEYSWDEIDVAS--AEREIAELEAELERLDA 682

                         490       500
                  ....*....|....*....|....*
gi 665399881 1089 DND---ALRQQCLKLNAVIRQQRKD 1110
Cdd:COG4913   683 SSDdlaALEEQLEELEAELEELEEE 707

PRK12704

phosphodiesterase; Provisional

779-903

8.23e-07

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.86 E-value: 8.23e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  779 LKRTHQMQLLDALEEARtkhEQIETSIRESCAQDREAIIE--KERTAIRERFERQLEEEQR--TQAEQRQKLTEEFAaer 854
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAK---RILEEAKKEAEAIKKEALLEakEEIHKLRNEFEKELRERRNelQKLEKRLLQKEENL--- 98

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 665399881  855 DRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQEEKYQN 903
Cdd:PRK12704   99 DRKLELLEKREEELEKKEKE-LEQKQQELEKKEEELEELIEEQLQELER 146

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

703-953

1.22e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.00 E-value: 1.22e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  703 EKVAALTRRLESQNQAWEhRLETELARTKETTMAGEKIRRERWVrentkkikELTVKGLEAEINkmncDHQREVTELKRT 782
Cdd:COG4913   617 AELAELEEELAEAEERLE-ALEAELDALQERREALQRLAEYSWD--------EIDVASAEREIA----ELEAELERLDAS 683

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  783 HQMqlLDALEE----ARTKHEQIETSIREscAQDREAIIEKERTAIRERFER---QLEE-EQRTQAEQRQKLTEEFAAE- 853
Cdd:COG4913   684 SDD--LAALEEqleeLEAELEELEEELDE--LKGEIGRLEKELEQAEEELDElqdRLEAaEDLARLELRALLEERFAAAl 759

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  854 RDRLQSELRQRENEHQARRQEALREQEQELEQA--------KFEMQERMAKQE--EKYQNRVNTIEQ----QYQADFElw 919
Cdd:COG4913   760 GDAVERELRENLEERIDALRARLNRAEEELERAmrafnrewPAETADLDADLEslPEYLALLDRLEEdglpEYEERFK-- 837

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 665399881  920 ktehENKTKLAQAEKENAIRQHYRAERD--RQLDEL 953
Cdd:COG4913   838 ----ELLNENSIEFVADLLSKLRRAIREikERIDPL 869

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

773-953

1.43e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.61 E-value: 1.43e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  773 QREVTELKRTHQmQLLDA------LEEARTKHEQIETSIREscAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKL 846
Cdd:COG4913   231 VEHFDDLERAHE-ALEDAreqielLEPIRELAERYAAARER--LAELEYLRAALRLWFAQRRLELLEAELEELRAELARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  847 TeefaAERDRLQS---ELRQRENEHQARRQEA----LREQEQELEQAKFEMQERMAKQEEkYQNRVNTIEQQY---QADF 916
Cdd:COG4913   308 E----AELERLEArldALREELDELEAQIRGNggdrLEQLEREIERLERELEERERRRAR-LEALLAALGLPLpasAEEF 382

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 665399881  917 -ELWKTEHENKTKLAQAEK--ENAIRQHYRAERD--RQLDEL 953
Cdd:COG4913   383 aALRAEAAALLEALEEELEalEEALAEAEAALRDlrRELREL 424

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

826-1025

1.67e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 51.82 E-value: 1.67e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   826 ERFERQLEEEQRTQAEQRQKLteEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRV 905
Cdd:pfam07888   30 ELLQNRLEECLQERAELLQAQ--EAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   906 NTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHElkmnrLKEKYEKDLVL 985
Cdd:pfam07888  108 ASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEA-----ERKQLQAKLQQ 182

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 665399881   986 AESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLEL 1025
Cdd:pfam07888  183 TEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKL 222

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

773-1102

1.70e-06

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 1.70e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   773 QREVTELK----RTHQMQLLDALEEARTKHEQIEtsIRESCAQD----REAIIEKERTAIRERFErQLEEEQRTQAEQRQ 844
Cdd:TIGR02168  173 RRKETERKlertRENLDRLEDILNELERQLKSLE--RQAEKAERykelKAELRELELALLVLRLE-ELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   845 KLTEEFAAERDRLQ-------------SELRQRENEHQARRQEALREQEqELEQAKFEMQERMAKQEEKYQNRVNTIEQQ 911
Cdd:TIGR02168  250 EAEEELEELTAELQeleekleelrlevSELEEEIEELQKELYALANEIS-RLEQQKQILRERLANLERQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   912 YQADFELWKTEHENKTKLAQAEKEnairqhyraerdrqldelvvrMEADALQHKEEHELKMNrLKEKYEKDLVLAEsvek 991
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEE---------------------LESLEAELEELEAELEE-LESRLEELEEQLE---- 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   992 SLREKYAETRGKLAEADAQVRNSQAEVKQLQLELshsKKMCGDIIMERDRLRDNLNADIQSELgvlnERHKQEMDQLQKR 1071
Cdd:TIGR02168  383 TLRSKVAQLELQIASLNNEIERLEARLERLEDRR---ERLQQEIEELLKKLEEAELKELQAEL----EELEEELEELQEE 455

                          330       340       350
                   ....*....|....*....|....*....|....
gi 665399881  1072 VHQTIQR---QEETIEILKGDNDALRQQCLKLNA 1102
Cdd:TIGR02168  456 LERLEEAleeLREELEEAEQALDAAERELAQLQA 489

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

810-963

2.04e-06

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 51.41 E-value: 2.04e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  810 AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQeqelEQAKfe 889
Cdd:COG2268   188 ALGRRKIAEIIRDARIAEAEAERETEIAIAQANREAEEAELEQEREIETARIAEAEAELAKKKAEERREA----ETAR-- 261

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665399881  890 mqermAKQEEKYqnRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQ-----HYRAERDRQLDELVVRMEADALQ 963
Cdd:COG2268   262 -----AEAEAAY--EIAEANAEREVQRQLEIAEREREIELQEKEAEREEAEleadvRKPAEAEKQAAEAEAEAEAEAIR 333

PRK02224

DNA double-strand break repair Rad50 ATPase;

751-1110

2.15e-06

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 51.96 E-value: 2.15e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  751 KKIKEL--TVKGLEAEINKM-----NCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAiiEKERTA 823
Cdd:PRK02224  199 KEEKDLheRLNGLESELAELdeeieRYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAET--EREREE 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  824 IRERFerqleeeqRTQAEQRQKLTEEFAAERDRlqSELRQRENEHQARRQEALREQEQELEQAKFEM---QERMAKQEEK 900
Cdd:PRK02224  277 LAEEV--------RDLRERLEELEEERDDLLAE--AGLDDADAEAVEARREELEDRDEELRDRLEECrvaAQAHNEEAES 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  901 YQNRVNTIEQQYQadfELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEaDAlqhkeehelkmnrlkekyE 980
Cdd:PRK02224  347 LREDADDLEERAE---ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG-DA------------------P 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  981 KDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSK-KMCG---------DIIMERDRLRDNLNA-- 1048
Cdd:PRK02224  405 VDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcPECGqpvegsphvETIEEDRERVEELEAel 484

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665399881 1049 -DIQSELGVLNERHKQ---------EMDQLQ---KRVHQTIQRQEETIEILKGDNDALRQQCLKLNAVIRQQRKD 1110
Cdd:PRK02224  485 eDLEEEVEEVEERLERaedlveaedRIERLEerrEDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREA 559

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

621-1092

3.75e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 51.38 E-value: 3.75e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   621 LPNHQLARRVIALSLRANELANAIHMSKEHVFQLRGEKqKSLRAEKSTAAAKLrdqkkhyEEVVTRHQGFIEQLLKDKGS 700
Cdd:pfam12128  227 IRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLH-FGYKSDETLIASRQ-------EERQETSAELNQLLRTLDDQ 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   701 LCEKVAALTRRLESQNQAWEHRlETELARTKETTMAGEKIRRERWVRE--------NTKKIKELTVKGLEAEINKMNCDH 772
Cdd:pfam12128  299 WKEKRDELNGELSAADAAVAKD-RSELEALEDQHGAFLDADIETAAADqeqlpswqSELENLEERLKALTGKHQDVTAKY 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   773 QRE--------VTELKRTHQMqlLDALEEARTK--------HEQIETSIRESC-AQDREAIIEKERTAIRERFER----- 830
Cdd:pfam12128  378 NRRrskikeqnNRDIAGIKDK--LAKIREARDRqlavaeddLQALESELREQLeAGKLEFNEEEYRLKSRLGELKlrlnq 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   831 -QLEEEQRTQAEQ--------RQKLTEEFaAERDRLQSELRQreneHQARRQEALREQEQElEQAKFEMQERMAKQEEKY 901
Cdd:pfam12128  456 aTATPELLLQLENfderieraREEQEAAN-AEVERLQSELRQ----ARKRRDQASEALRQA-SRRLEERQSALDELELQL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   902 QNRVNTIEQQYQADFELWKtehENKTKLAQAEKENAIRQHYRAERDRQLDELV---VRMEADALQHKE--EHELKMNRLK 976
Cdd:pfam12128  530 FPQAGTLLHFLRKEAPDWE---QSIGKVISPELLHRTDLDPEVWDGSVGGELNlygVKLDLKRIDVPEwaASEEELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   977 EKYEKDLVLAESVEKSLREKYAETRGKLAEADAQ-------VRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAD 1049
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASREetfartaLKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNS 686

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 665399881  1050 IQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIEILKGDNDA 1092
Cdd:pfam12128  687 LEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDA 729

PRK02224

DNA double-strand break repair Rad50 ATPase;

788-1060

3.99e-06

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 51.19 E-value: 3.99e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  788 LDALEE-------ARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEqrqklTEEFAAERDRLQS- 859
Cdd:PRK02224  161 LGKLEEyrerasdARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEE-----IERYEEQREQAREt 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  860 --ELRQRENEHQARRQEAlreqeQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELwktEHENKTKLAQAEKENA 937
Cdd:PRK02224  236 rdEADEVLEEHEERREEL-----ETLEAEIEDLRETIAETEREREELAEEVRDLRERLEEL---EEERDDLLAEAGLDDA 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  938 ------IRQHYRAERDRQLDELVVRMEADALQHKEEHElkmnRLKEKYEKdlvlAESVEKSLREKYAETRGKLAEADAQV 1011
Cdd:PRK02224  308 daeaveARREELEDRDEELRDRLEECRVAAQAHNEEAE----SLREDADD----LEERAEELREEAAELESELEEAREAV 379

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 665399881 1012 RNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDnLNADIQSELGVLNER 1060
Cdd:PRK02224  380 EDRREEIEELEEEIEELRERFGDAPVDLGNAED-FLEELREERDELRER 427

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

862-1102

5.56e-06

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.83 E-value: 5.56e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   862 RQRENEHQARRQE--ALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIR 939
Cdd:TIGR02168  666 AKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   940 QHYRAERDRQLDELVVRME------ADALQHKEEHELKMNRLKEKYEKDLVLAesveKSLREKYAETRGKLAEADAQVRN 1013
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEeleerlEEAEEELAEAEAEIEELEAQIEQLKEEL----KALREALDELRAELTLLNEEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  1014 SQAEVKQLQLELSHSKKMCGDIIMERDRLRDNL--NADIQSELGVLNERHKQEMDQLQKRVHQTIQR----------QEE 1081
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIesLAAEIEELEELIEELESELEALLNERASLEEAlallrseleeLSE 901

                          250       260
                   ....*....|....*....|.
gi 665399881  1082 TIEILKGDNDALRQQCLKLNA 1102
Cdd:TIGR02168  902 ELRELESKRSELRRELEELRE 922

PRK12704

phosphodiesterase; Provisional

813-986

5.88e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.16 E-value: 5.88e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  813 REAIIEKERTAIRERFERQLEEEQR-TQAEQRQKLTE---EFAAERDRLQSELRQRENEHQaRRQEALREQEQELEQakf 888
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAKRILEEAKKeAEAIKKEALLEakeEIHKLRNEFEKELRERRNELQ-KLEKRLLQKEENLDR--- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  889 eMQERMAKQEEKYQNRVNTIEQQYQaDFELWKTEHENKTKLAQAEKENaIRQHYRAE-RDRQLDELVVRMEADALQH-KE 966
Cdd:PRK12704  101 -KLELLEKREEELEKKEKELEQKQQ-ELEKKEEELEELIEEQLQELER-ISGLTAEEaKEILLEKVEEEARHEAAVLiKE 177

                         170       180
                  ....*....|....*....|
gi 665399881  967 EHELKMNRLKEKYEKDLVLA 986
Cdd:PRK12704  178 IEEEAKEEADKKAKEILAQA 197

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

659-900

6.76e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 6.76e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  659 QKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEhRLETELARTkETTMAGE 738
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA-ALEAELAEL-EKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  739 KIRRERWVRENTKKIKELTVKGLEAEINKMNcdHQREVTELKRThqMQLLDALEEARTkhEQIETsiresCAQDREAIIE 818
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQPPLALLL--SPEDFLDAVRR--LQYLKYLAPARR--EQAEE-----LRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  819 KERTAIRERfeRQLEEEQRTQAEQRQKLTEEfAAERDRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQE 898
Cdd:COG4942   165 LRAELEAER--AELEALLAELEEERAALEAL-KAERQKLLARLEKELAELAAELAE-LQQEAEELEALIARLEAEAAAAA 240


                  ..
gi 665399881  899 EK 900
Cdd:COG4942   241 ER 242

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

657-1067

7.98e-06

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.22 E-value: 7.98e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   657 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLcekvAALTRRLESQNQAWEHRLETELARTKETTma 736
Cdd:pfam12128  478 EEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSAL----DELELQLFPQAGTLLHFLRKEAPDWEQSI-- 551

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   737 GEKIRRERWVREN-------TKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESC 809
Cdd:pfam12128  552 GKVISPELLHRTDldpevwdGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQAN 631

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   810 AQDREAIIEKERTAI-----RERFeRQLEEEQRTQAEQRQKLTEE---FAAERDR-LQSELRQRENEHQA---------- 870
Cdd:pfam12128  632 GELEKASREETFARTalknaRLDL-RRLFDEKQSEKDKKNKALAErkdSANERLNsLEAQLKQLDKKHQAwleeqkeqkr 710

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   871 ----RRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQaEKENAIRQHYRAER 946
Cdd:pfam12128  711 eartEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKR-EIRTLERKIERIAV 789

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   947 DRQ-LDELVVRMEADALQHK--------------EEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQV 1011
Cdd:pfam12128  790 RRQeVLRYFDWYQETWLQRRprlatqlsnieraiSELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM 869

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665399881  1012 R-----NSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSELGVLNERHKQEMDQ 1067
Cdd:pfam12128  870 SklatlKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHSGSGLAE 930

PRK03918

DNA double-strand break repair ATPase Rad50;

691-1026

8.08e-06

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.06 E-value: 8.08e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  691 IEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNc 770
Cdd:PRK03918  340 LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK- 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  771 dhqREVTELKrthqmqllDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRErferqLEEEQRTQAEQRQKLTEEF 850
Cdd:PRK03918  419 ---KEIKELK--------KAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKR-----IEKELKEIEEKERKLRKEL 482

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  851 AAERDRLQSELRQRENEHQArrqEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLA 930
Cdd:PRK03918  483 RELEKVLKKESELIKLKELA---EQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA 559

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  931 QAEKEnairqhyRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVE---------KSLREKYAETR 1001
Cdd:PRK03918  560 ELEKK-------LDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKelereekelKKLEEELDKAF 632

                         330       340
                  ....*....|....*....|....*
gi 665399881 1002 GKLAEADAQVRNSQAEVKQLQLELS 1026
Cdd:PRK03918  633 EELAETEKRLEELRKELEELEKKYS 657

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

777-953

9.54e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 9.54e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  777 TELKRTHQMQLLDALEEARTKHEQIETSIRE----SCAQDREAIIEKERTAIRERFERQLEeeqrtQAEQRQKLTEEFAA 852
Cdd:COG4717   332 PDLSPEELLELLDRIEELQELLREAEELEEElqleELEQEIAALLAEAGVEDEEELRAALE-----QAEEYQELKEELEE 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  853 ERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEqQYQADFELWKTEHEN---KTKL 929
Cdd:COG4717   407 LEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELE-QLEEDGELAELLQELeelKAEL 485

                         170       180       190
                  ....*....|....*....|....*....|..
gi 665399881  930 AQAEKENA--------IRQHYRAERDRQLDEL 953
Cdd:COG4717   486 RELAEEWAalklalelLEEAREEYREERLPPV 517

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

759-1086

9.87e-06

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.07 E-value: 9.87e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   759 KGLEAEINKMncdhQREVTELKRtHQMQLLDALEEARTKHEQIETSIrESCAQDREAiiEKERTAIRERFERQLEEEQrt 838
Cdd:TIGR02169  684 EGLKRELSSL----QSELRRIEN-RLDELSQELSDASRKIGEIEKEI-EQLEQEEEK--LKERLEELEEDLSSLEQEI-- 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   839 qaeqrqkltEEFAAERDRLQSELRQREnEHQARRQEALREQEQELEQAKF-EMQERMAKQEEKYQNRVNTIEqqyqadfE 917
Cdd:TIGR02169  754 ---------ENVKSELKELEARIEELE-EDLHKLEEALNDLEARLSHSRIpEIQAELSKLEEEVSRIEARLR-------E 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   918 LWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELvvrmeadalqHKEEHELKMNrlKEKYEKDLVLAESVEKSLREKY 997
Cdd:TIGR02169  817 IEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSI----------EKEIENLNGK--KEELEEELEELEAALRDLESRL 884

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   998 AETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLnADIQSELGVLNERHKQEMDqlQKRVHQTIQ 1077
Cdd:TIGR02169  885 GDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL-SEIEDPKGEDEEIPEEELS--LEDVQAELQ 961


                   ....*....
gi 665399881  1078 RQEETIEIL 1086
Cdd:TIGR02169  962 RVEEEIRAL 970

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

714-913

1.03e-05

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 49.56 E-value: 1.03e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   714 SQNQAWEHRLETElaRTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKmncdHQREVTELKRTHQMQLLDalEE 793
Cdd:pfam15709  329 EQEKASRDRLRAE--RAEMRRLEVERKRREQEEQRRLQQEQLERAEKMREELEL----EQQRRFEEIRLRKQRLEE--ER 400

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   794 ARTKHEQIETSIRESCAQDREAIIEKE--RTAIRERFERQLEEEQRTQAE-QRQKLTEEFAAERDRLQSELRQREnehqa 870
Cdd:pfam15709  401 QRQEEEERKQRLQLQAAQERARQQQEEfrRKLQELQRKKQQEEAERAEAEkQRQKELEMQLAEEQKRLMEMAEEE----- 475

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 665399881   871 rRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQ 913
Cdd:pfam15709  476 -RLEYQRQKQEAEEKARLEAEERRQKEEEAARLALEEAMKQAQ 517

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

749-1113

1.27e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.38 E-value: 1.27e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  749 NTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERF 828
Cdd:COG4717    69 NLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERL 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  829 E---------RQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQEE 899
Cdd:COG4717   149 EeleerleelRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE-LQQRLAELEEELEEAQEELEELEE 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  900 KYQNRVNTIEQQYQAD-----------------------------------------------FELWKTEHENKTKLAQA 932
Cdd:COG4717   228 ELEQLENELEAAALEErlkearlllliaaallallglggsllsliltiagvlflvlgllallfLLLAREKASLGKEAEEL 307

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  933 EKENAIRQHYRAERDRQLDEL---------VVRMEADALQHKEEHELKMNRLKEKYEKDlVLAESVEKSLREKYAETRGK 1003
Cdd:COG4717   308 QALPALEELEEEELEELLAALglppdlspeELLELLDRIEELQELLREAEELEEELQLE-ELEQEIAALLAEAGVEDEEE 386

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881 1004 LAEADAQVRnsqaEVKQLQLELSHSKKMCGDIIMERDRLRDNLN-ADIQSELGVLnERHKQEMDQLQKRVHQTIQRQEET 1082
Cdd:COG4717   387 LRAALEQAE----EYQELKEELEELEEQLEELLGELEELLEALDeEELEEELEEL-EEELEELEEELEELREELAELEAE 461

                         410       420       430
                  ....*....|....*....|....*....|...
gi 665399881 1083 IEILKGDN--DALRQQCLKLNAVIRQQRKDYCV 1113
Cdd:COG4717   462 LEQLEEDGelAELLQELEELKAELRELAEEWAA 494

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

792-1069

1.49e-05

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 49.45 E-value: 1.49e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   792 EEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFE------------------------RQLEEEQRTQAEQRQKL- 846
Cdd:pfam12128  214 PKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNtlesaelrlshlhfgyksdetliaSRQEERQETSAELNQLLr 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   847 --TEEFAAERDRLQSELR-QRENEHQARRQ-EALREQEQELEQAKFEMQERMAKQEEKYQN--------------RVNTI 908
Cdd:pfam12128  294 tlDDQWKEKRDELNGELSaADAAVAKDRSElEALEDQHGAFLDADIETAAADQEQLPSWQSelenleerlkaltgKHQDV 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   909 EQQYQAdfELWKTEHENKTKLAQAEKEnaiRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKyekdlvlaes 988
Cdd:pfam12128  374 TAKYNR--RRSKIKEQNNRDIAGIKDK---LAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEE---------- 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   989 vEKSLREKYAETRGKLAEADA------QVRNSQAEVKQLQLELSHSKKMCGDIIMER---DRLRDNLNADIQSELGVLNE 1059
Cdd:pfam12128  439 -EYRLKSRLGELKLRLNQATAtpelllQLENFDERIERAREEQEAANAEVERLQSELrqaRKRRDQASEALRQASRRLEE 517

                          330
                   ....*....|
gi 665399881  1060 RhKQEMDQLQ 1069
Cdd:pfam12128  518 R-QSALDELE 526

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

814-935

1.53e-05

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 49.05 E-value: 1.53e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  814 EAIIEKERTAI---RERFERQLE--EEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKf 888
Cdd:PRK00409  501 ENIIEEAKKLIgedKEKLNELIAslEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAI- 579

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 665399881  889 emqeRMAKQE-EKYQNRVNTIEQQYQADFELWKTEhENKTKLAQAEKE 935
Cdd:PRK00409  580 ----KEAKKEaDEIIKELRQLQKGGYASVKAHELI-EARKRLNKANEK 622

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

869-1109

2.23e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 2.23e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  869 QARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKE----NAIRQHYRA 944
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElaelEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  945 ERDRQLDELVVRMeaDALQhkeehelKMNRlkEKYEKDLVLAESVEKSLR-----EKYAETRGKLAEadaQVRNSQAEVK 1019
Cdd:COG4942    98 ELEAQKEELAELL--RALY-------RLGR--QPPLALLLSPEDFLDAVRrlqylKYLAPARREQAE---ELRADLAELA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881 1020 QLQLELSHskkmcgdiimERDRLRdNLNADIQSELGVLnERHKQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLK 1099
Cdd:COG4942   164 ALRAELEA----------ERAELE-ALLAELEEERAAL-EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                         250
                  ....*....|
gi 665399881 1100 LNAVIRQQRK 1109
Cdd:COG4942   232 LEAEAAAAAE 241

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

792-933

2.39e-05

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 48.41 E-value: 2.39e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   792 EEARTKHEQIETS--IRESCAQDREAIIEkertAIRERFERQLEEEQRTQAEQR-QKLTEEFAAERDRLQSE-------- 860
Cdd:pfam15709  359 EQRRLQQEQLERAekMREELELEQQRRFE----EIRLRKQRLEEERQRQEEEERkQRLQLQAAQERARQQQEefrrklqe 434

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665399881   861 LRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEK----YQNRVNTIEQQYQADFELWKTEHENKTKLAQAE 933
Cdd:pfam15709  435 LQRKKQQEEAERAEAEKQRQKELEMQLAEEQKRLMEMAEEerleYQRQKQEAEEKARLEAEERRQKEEEAARLALEE 511

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

625-907

2.80e-05

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 48.21 E-value: 2.80e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   625 QLARRVIALSLRANElaNAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRH----QGFIEQLLKDKGS 700
Cdd:pfam09731  139 SKAESATAVAKEAKD--DAIQAVKAHTDSLKEASDTAEISREKATDSALQKAEALAEKLKEVInlakQSEEEAAPPLLDA 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   701 LCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKirRERWVRENTKKIKELTV------KGLEAEINKMNCDHQR 774
Cdd:pfam09731  217 APETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASE--RIVFQQELVSIFPDIIPvlkednLLSNDDLNSLIAHAHR 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   775 EVTELKRthQMQLLDALEEARtkheqIETSIRESCAQDREAIiEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFaaeR 854
Cdd:pfam09731  295 EIDQLSK--KLAELKKREEKH-----IERALEKQKEELDKLA-EELSARLEEVRAADEAQLRLEFEREREEIRESY---E 363

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 665399881   855 DRLQSELRQRENEHQARRQEALREQEQELE-QAKFEMQERMAKQEEKYQNRVNT 907
Cdd:pfam09731  364 EKLRTELERQAEAHEEHLKDVLVEQEIELQrEFLQDIKEKVEEERAGRLLKLNE 417

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

799-973

3.00e-05

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 47.95 E-value: 3.00e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  799 EQIETSIRESCAQDREAII---EKERTAIRERFERQLEEEQRTQAEQRqklteefaAERDRLQSELRQRENEHQARRQEA 875
Cdd:COG2268   196 EIIRDARIAEAEAERETEIaiaQANREAEEAELEQEREIETARIAEAE--------AELAKKKAEERREAETARAEAEAA 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  876 LREQEQELEQAKfEMQERMAKQEEkyQNRVNTIEQQYQAdfelwKTEHENKTKLAQAEKENAIRQHyRAERDRQLDELVV 955
Cdd:COG2268   268 YEIAEANAEREV-QRQLEIAERER--EIELQEKEAEREE-----AELEADVRKPAEAEKQAAEAEA-EAEAEAIRAKGLA 338

                         170
                  ....*....|....*...
gi 665399881  956 rmEADALQHKEEHELKMN 973
Cdd:COG2268   339 --EAEGKRALAEAWNKLG 354

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

825-1026

4.32e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.07 E-value: 4.32e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  825 RERFERQLEEEQRTQAEQRQKLtEEFAAERDRLQSELRQREnehqaRRQEALREQEQELEQAKFEMQERMA---KQEEKY 901
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKEL-AALKKEEKALLKQLAALE-----RRIAALARRIRALEQELAALEAELAeleKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  902 QNRVNTIEQQYQADF-ELWKTEHENKTKL-------AQAEKENAIRQHYRAERDRQLDELVVRME--ADALQHKEEHELK 971
Cdd:COG4942    96 RAELEAQKEELAELLrALYRLGRQPPLALllspedfLDAVRRLQYLKYLAPARREQAEELRADLAelAALRAELEAERAE 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 665399881  972 MNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELS 1026
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230

tolA

PRK09510

cell envelope integrity inner membrane protein TolA; Provisional

823-1021

5.44e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 46.72 E-value: 5.44e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  823 AIRERFERQLEEE--QRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEM----QERMAK 896
Cdd:PRK09510   59 AVVEQYNRQQQQQksAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAAlkqkQAEEAA 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  897 QEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAirqhyRAERDRQLDELVVRMEADALQHKEEHELKMNRLK 976
Cdd:PRK09510  139 AKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKA-----AAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAA 213

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 665399881  977 EKYEKDLVLAESV-EKSLREKYAETRGKLAEADAQVRNSQAEVKQL 1021
Cdd:PRK09510  214 EAKKKAAAEAKAAaAKAAAEAKAAAEKAAAAKAAEKAAAAKAAAEV 259

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

625-1080

5.79e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.60 E-value: 5.79e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  625 QLARRVIALSLRANELANAIHMSK----EHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKG- 699
Cdd:COG4913   259 ELAERYAAARERLAELEYLRAALRlwfaQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGd 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  700 ---SLCEKVAALTRRLESQNQAWEhRLETELARTKETTMAGEKI---RRERWVR-----ENTKKIKELTVKGLEAEINKM 768
Cdd:COG4913   339 rleQLEREIERLERELEERERRRA-RLEALLAALGLPLPASAEEfaaLRAEAAAllealEEELEALEEALAEAEAALRDL 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  769 NCDH---QREVTELKRT------HQMQLLDALEEA-----------------RTKHEQIETSI-------------RESC 809
Cdd:COG4913   418 RRELrelEAEIASLERRksnipaRLLALRDALAEAlgldeaelpfvgelievRPEEERWRGAIervlggfaltllvPPEH 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  810 AQDREAIIEKERTAIRERFER---QLEEEQRTQAEQRQ---KLTEEFAAERDRLQSELRQREN----------------- 866
Cdd:COG4913   498 YAAALRWVNRLHLRGRLVYERvrtGLPDPERPRLDPDSlagKLDFKPHPFRAWLEAELGRRFDyvcvdspeelrrhprai 577

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  867 -------------EHQARRQ---------------EALREQEQELEQAKFEMQERMAKQEEKYQNRvntieQQYQADFEL 918
Cdd:COG4913   578 tragqvkgngtrhEKDDRRRirsryvlgfdnraklAALEAELAELEEELAEAEERLEALEAELDAL-----QERREALQR 652

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  919 WKTEHENKTKLAQAEKEnairqhyRAERDRQLDELvvRMEADALQhkeehelkmnRLKEKYEKdlvlAESVEKSLREKYA 998
Cdd:COG4913   653 LAEYSWDEIDVASAERE-------IAELEAELERL--DASSDDLA----------ALEEQLEE----LEAELEELEEELD 709

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  999 ETRGKLAEADAQVRNSQAEVKQLQLELShskkmcGDIIMERDRLRDNLNADIQSELGvlNERHKQEMDQLQKRVHQTIQR 1078
Cdd:COG4913   710 ELKGEIGRLEKELEQAEEELDELQDRLE------AAEDLARLELRALLEERFAAALG--DAVERELRENLEERIDALRAR 781


                  ..
gi 665399881 1079 QE 1080
Cdd:COG4913   782 LN 783

mukB

chromosome partition protein MukB;

772-1096

6.40e-05

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.26 E-value: 6.40e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  772 HQREVTELKRthqmQLLDALEEARTKHEQIETSIRESCAQ-DREAIIEKERTAIRERFerQLEEEQRTQAEQRQKLTEEF 850
Cdd:PRK04863  284 HLEEALELRR----ELYTSRRQLAAEQYRLVEMARELAELnEAESDLEQDYQAASDHL--NLVQTALRQQEKIERYQADL 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  851 AAERDRL--QSELRQRENEHQARRQEALREQEQELEQAK---------FEMQERMAKQeekYQNRVNTIEQQYQ----AD 915
Cdd:PRK04863  358 EELEERLeeQNEVVEEADEQQEENEARAEAAEEEVDELKsqladyqqaLDVQQTRAIQ---YQQAVQALERAKQlcglPD 434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  916 FEL-----WKTEHENKTKLA-----QAEK-----ENAIRQHYRAErdrqldELVVRMeADALQHKEEHElKMNRLKEKYE 980
Cdd:PRK04863  435 LTAdnaedWLEEFQAKEQEAteellSLEQklsvaQAAHSQFEQAY------QLVRKI-AGEVSRSEAWD-VARELLRRLR 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  981 KDLVLAESVEkSLREKYAETRGKLaeadaqvrNSQAEVKQLQLELSHskkmcgdiimerdrlRDNLNADIQSELGVLNER 1060
Cdd:PRK04863  507 EQRHLAEQLQ-QLRMRLSELEQRL--------RQQQRAERLLAEFCK---------------RLGKNLDDEDELEQLQEE 562

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 665399881 1061 HKQEMDQLQKRVHQTIQRQEET---IEILKGDNDALRQQ 1096
Cdd:PRK04863  563 LEARLESLSESVSEARERRMALrqqLEQLQARIQRLAAR 601

tolA

PRK09510

cell envelope integrity inner membrane protein TolA; Provisional

789-937

6.47e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 46.72 E-value: 6.47e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  789 DALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAErdrlQSELRQRENEH 868
Cdd:PRK09510   76 RAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAK----AAAAAKAKAEA 151

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665399881  869 QARRQEALREQEQElEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA 937
Cdd:PRK09510  152 EAKRAAAAAKKAAA-EAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKA 219

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

729-1102

6.81e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 47.27 E-value: 6.81e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   729 RTKETTMAGEKIRRERWVRENTKKIKeltvKGLEAEINKMncDHQREVTELKRTHQMQLLDALEEARTKHEQietSIRES 808
Cdd:TIGR00618  164 EKKELLMNLFPLDQYTQLALMEFAKK----KSLHGKAELL--TLRSQLLTLCTPCMPDTYHERKQVLEKELK---HLREA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   809 CAQDRE--AIIEKERTAIRERFERQLE-EEQRTQAEQRQKLTEEFAAERDRLQ---------------SELRQRENEHQA 870
Cdd:TIGR00618  235 LQQTQQshAYLTQKREAQEEQLKKQQLlKQLRARIEELRAQEAVLEETQERINrarkaaplaahikavTQIEQQAQRIHT 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   871 RRQEALREQEQELEQAKFEMQERMAKQEEKyqnrvnTIEQQYQADFELWKTEHENKTK-LAQAEKENAIRQHYRAERdrq 949
Cdd:TIGR00618  315 ELQSKMRSRAKLLMKRAAHVKQQSSIEEQR------RLLQTLHSQEIHIRDAHEVATSiREISCQQHTLTQHIHTLQ--- 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   950 ldelvvrmeadalQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAEtRGKLAEADAQVRNSQAEVKQLQLELSHSK 1029
Cdd:TIGR00618  386 -------------QQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDL-QGQLAHAKKQQELQQRYAELCAAAITCTA 451

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 665399881  1030 KMCGDIIMERDRLRDNLNADIQSElgvlnerhkQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNA 1102
Cdd:TIGR00618  452 QCEKLEKIHLQESAQSLKEREQQL---------QTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNP 515

FAM184

pfam15665

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

765-983

6.85e-05

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 45.42 E-value: 6.85e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   765 INKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAiiekertairerfeRQLEEEQRTQAEQRQ 844
Cdd:pfam15665    5 LNTKNDEHEAEIQALKEAHEEEIQQILAETREKILQYKSKIGEELDLKRRI--------------QTLEESLEQHERMKR 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   845 KLTEEFAAERDRLQSELRQRENEHQARrqeaLREQEQELEQAKFEMQER-------MAKQEEKYQNRVNTIEQQYQADFE 917
Cdd:pfam15665   71 QALTEFEQYKRRVEERELKAEAEHRQR----VVELSREVEEAKRAFEEKlesfeqlQAQFEQEKRKALEELRAKHRQEIQ 146

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665399881   918 LWKTEHENKTKLAQAEKENaIRQHYRAERDrQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDL 983
Cdd:pfam15665  147 ELLTTQRAQSASSLAEQEK-LEELHKAELE-SLRKEVEDLRKEKKKLAEEYEQKLSKAQAFYEREL 210

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

958-1109

7.14e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 7.14e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  958 EADALQHK-EEHELKMNRLKEKYekDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDI- 1035
Cdd:COG3206   183 QLPELRKElEEAEAALEEFRQKN--GLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELl 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881 1036 ----IMERDRLRDNLNADIQSELGVLNERH------KQEMDQLQKRVHQTIQRQEETIEIlkgDNDALRQQCLKLNAVIR 1105
Cdd:COG3206   261 qspvIQQLRAQLAELEAELAELSARYTPNHpdvialRAQIAALRAQLQQEAQRILASLEA---ELEALQAREASLQAQLA 337


                  ....
gi 665399881 1106 QQRK 1109
Cdd:COG3206   338 QLEA 341

ClpA

COG0542

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...

781-898

7.75e-05

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 47.00 E-value: 7.75e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  781 RTHQMQLLDALEEARTKHEQIETsirescaqDREAIIEKERTAIRERFERqLEEEQRTQAEQRQKLTEEFAAERDRLQSE 860
Cdd:COG0542   403 RMEIDSKPEELDELERRLEQLEI--------EKEALKKEQDEASFERLAE-LRDELAELEEELEALKARWEAEKELIEEI 473

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 665399881  861 LRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQE 898
Cdd:COG0542   474 QELKEELEQRYGKIPELEKELAELEEELAELAPLLREE 511

Caldesmon

pfam02029

Caldesmon;

799-1087

9.54e-05

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 46.40 E-value: 9.54e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   799 EQIETSIRESCAQDREAIIEKERTAIRERfERQLEEEQRTQAEQRQKLTEEFAA--ERDRLQSELRQRENEHQARRQEAL 876
Cdd:pfam02029    5 EEAARERRRRAREERRRQKEEEEPSGQVT-ESVEPNEHNSYEEDSELKPSGQGGldEEEAFLDRTAKREERRQKRLQEAL 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   877 REQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDrqldelvvR 956
Cdd:pfam02029   84 ERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEE--------E 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   957 MEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAeadAQVRNSQAEVKQLQLELSHSKKMCGDII 1036
Cdd:pfam02029  156 GEEEEDKSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGH---PEVKSQNGEEEVTKLKVTTKRRQGGLSQ 232

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 665399881  1037 MERDRLRDNLNADIQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIEILK 1087
Cdd:pfam02029  233 SQEREEEAEVFLEAEQKLEELRRRRQEKESEEFEKLRQKQQEAELELEELK 283

PRK07353

F0F1 ATP synthase subunit B'; Validated

819-886

1.01e-04

F0F1 ATP synthase subunit B'; Validated

Pssm-ID: 235999 [Multi-domain] Cd Length: 140 Bit Score: 43.45 E-value: 1.01e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665399881  819 KERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSE-LRQRENEHQARRQEALREQEQELEQA 886
Cdd:PRK07353   49 KERLAEAEKLEAQYEQQLASARKQAQAVIAEAEAEADKLAAEaLAEAQAEAQASKEKARREIEQQKQAA 117

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

787-1018

1.08e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.30 E-value: 1.08e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  787 LLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAirerfeRQLEEEQRTQAEQRQKLTEEFAAERDRLqSELRQREN 866
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEA------EEKEEEYAELQEELEELEEELEELEAEL-EELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  867 EHqaRRQEALREQEQELEQAKFEMQErmakqeekYQNRVNTIEQQYQAdfelwktEHENKTKLAQAEKEnaiRQHYRAER 946
Cdd:COG4717   120 KL--EKLLQLLPLYQELEALEAELAE--------LPERLEELEERLEE-------LRELEEELEELEAE---LAELQEEL 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 665399881  947 DRQLDELVVRMEADALQHKEEHELKMNRLKEkYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEV 1018
Cdd:COG4717   180 EELLEQLSLATEEELQDLAEELEELQQRLAE-LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARL 250

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

632-970

1.19e-04

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.50 E-value: 1.19e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   632 ALSLRANELANAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEV----VTRHQGFIEQllkdkgSLCEKVAA 707
Cdd:TIGR00618  574 ILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQdlqdVRLHLQQCSQ------ELALKLTA 647

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   708 LTRRLEsqNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQL 787
Cdd:TIGR00618  648 LHALQL--TLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIEN 725

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   788 LD--ALEEARTKHEQIETSIRESCAQDREAIieKERTAIRER-FERQLEEEQR-TQAEQRQKLTEEFAAERDRLQSELRQ 863
Cdd:TIGR00618  726 ASssLGSDLAAREDALNQSLKELMHQARTVL--KARTEAHFNnNEEVTAALQTgAELSHLAAEIQFFNRLREEDTHLLKT 803

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   864 RENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQnRVNTIEQQYQADfelwkteHENKTKLAQAEKENAiRQHYR 943
Cdd:TIGR00618  804 LEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSA-TLGEITHQLLKY-------EECSKQLAQLTQEQA-KIIQL 874

                          330       340
                   ....*....|....*....|....*..
gi 665399881   944 AERDRQLDELVVRMEADALQhKEEHEL 970
Cdd:TIGR00618  875 SDKLNGINQIKIQFDGDALI-KFLHEI 900

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

747-961

1.37e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 1.37e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  747 RENTKKIKEL--TVKGLEAEINKMNCDHQREVTELKRTHQM--QLLDALEEARTKHEQIETSIREscAQDREAIIEKERT 822
Cdd:COG4942    23 AEAEAELEQLqqEIAELEKELAALKKEEKALLKQLAALERRiaALARRIRALEQELAALEAELAE--LEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  823 AIRERFERQLEEEQRTQAEQRQKL---TEEFAAERDRLQ-----SELRQRENEHQARRQEALREQEQELEQAKFEMQERM 894
Cdd:COG4942   101 AQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQylkylAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665399881  895 AKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnairqhyraerDRQLDELVVRMEADA 961
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE-----------AEELEALIARLEAEA 236

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

720-978

1.55e-04

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 45.29 E-value: 1.55e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   720 EHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHE 799
Cdd:pfam13868   87 QKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   800 QIETSIREscaqdrEAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQ 879
Cdd:pfam13868  167 REEEREAE------REEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   880 EQELEQAKFEMQERMAKQEEKYQNRVntieqqyqadfeLWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEA 959
Cdd:pfam13868  241 REEQIELKERRLAEEAEREEEEFERM------------LRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAA 308

                          250
                   ....*....|....*....
gi 665399881   960 DALQHKEEHELKMNRLKEK 978
Cdd:pfam13868  309 EREEELEEGERLREEEAER 327

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

785-897

1.98e-04

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 44.49 E-value: 1.98e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  785 MQLLDALEEA--RTKHEQIETSIRESCAQDREAIIEKERTAIRERF---ERQLEEEQRTQAEQRQKLTEEFAAERDRLQS 859
Cdd:cd16269   176 LQSKEAEAEAilQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQrelEQKLEDQERSYEEHLRQLKEKMEEERENLLK 255

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 665399881  860 ELrQRENEHQarrqeaLREQEQELEQAKFEMQERMAKQ 897
Cdd:cd16269   256 EQ-ERALESK------LKEQEALLEEGFKEQAELLQEE 286

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

811-998

2.24e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 45.71 E-value: 2.24e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  811 QDREAiiekertAIRERfERQLEEEQRTQAEQR--QKLTEE----FAA-------ERDRLQSELRQRENEHQARRQEALR 877
Cdd:COG3096   232 QDMEA-------ALREN-RMTLEAIRVTQSDRDlfKHLITEatnyVAAdymrhanERRELSERALELRRELFGARRQLAE 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  878 EQEQeleqakfemQERMAKQEEKYQNRVNTIEQQYQAdfelwKTEHENK--TKLAQAEKenaiRQHYRAErdrqLDELVV 955
Cdd:COG3096   304 EQYR---------LVEMARELEELSARESDLEQDYQA-----ASDHLNLvqTALRQQEK----IERYQED----LEELTE 361

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 665399881  956 RMEADALQHKEEHElkmnrLKEKYEKDLVLAESVEKSLREKYA 998
Cdd:COG3096   362 RLEEQEEVVEEAAE-----QLAEAEARLEAAEEEVDSLKSQLA 399

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

625-916

2.83e-04

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.05 E-value: 2.83e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   625 QLARRVIALSLRANELANAIHMSKEHVFQLRG---------EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLL 695
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEelaeaeaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   696 KDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRrerwvrENTKKIKELT--VKGLEAEINKMNCDHQ 773
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE------ELESELEALLneRASLEEALALLRSELE 897

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   774 REVTELK--RTHQMQLLDALEEARTKHEQIETsirescaqdREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFA 851
Cdd:TIGR02168  898 ELSEELRelESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665399881   852 AERDRLqSELRQR-------------ENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADF 916
Cdd:TIGR02168  969 EARRRL-KRLENKikelgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQVNENF 1045

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

823-1024

2.91e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.01 E-value: 2.91e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  823 AIRERFERQLEEEQRTQAEQRQKLTEEfaaERDRLQSELRQRENEHQARRQE----ALREQEQELEQAKFEMQERMAK-- 896
Cdd:COG3206   156 ALAEAYLEQNLELRREEARKALEFLEE---QLPELRKELEEAEAALEEFRQKnglvDLSEEAKLLLQQLSELESQLAEar 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  897 -QEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDE--LVVRMEA--DALQHKEEHELK 971
Cdd:COG3206   233 aELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNhpDVIALRAqiAALRAQLQQEAQ 312

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 665399881  972 mnRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEAdaqvrnSQAEVKQLQLE 1024
Cdd:COG3206   313 --RILASLEAELEALQAREASLQAQLAQLEARLAEL------PELEAELRRLE 357

PRK02224

DNA double-strand break repair Rad50 ATPase;

775-1027

3.22e-04

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 45.03 E-value: 3.22e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  775 EVTELKRTHQMQLLDALEEARTKHEQIETSIrESCAQDREAiiEKERTAIRERFER--QLEEEQRTQAEQRQKLTEEFAA 852
Cdd:PRK02224  468 ETIEEDRERVEELEAELEDLEEEVEEVEERL-ERAEDLVEA--EDRIERLEERREDleELIAERRETIEEKRERAEELRE 544

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  853 ERDRLQSELRQRENEHQARRQEAlreqEQELEQAKFEMQERMAKQEEKyqNRVNTIEQQYQADFELWKTEHENKTKLAQ- 931
Cdd:PRK02224  545 RAAELEAEAEEKREAAAEAEEEA----EEAREEVAELNSKLAELKERI--ESLERIRTLLAAIADAEDEIERLREKREAl 618

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  932 AEKENAIRQHYRAERDRQlDELVVRMEADALQHKEEHelkmnrlKEKYEKDLvlaESVEKSLREKyAETRGKLAEADAQV 1011
Cdd:PRK02224  619 AELNDERRERLAEKRERK-RELEAEFDEARIEEARED-------KERAEEYL---EQVEEKLDEL-REERDDLQAEIGAV 686

                         250
                  ....*....|....*.
gi 665399881 1012 RNSQAEVKQLQLELSH 1027
Cdd:PRK02224  687 ENELEELEELRERREA 702

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

691-892

3.40e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.93 E-value: 3.40e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  691 IEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTmagekiRRERWVRENTKKIKELTVKGLEAEINKMnc 770
Cdd:COG1196   587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA------RLEAALRRAVTLAGRLREVTLEGEGGSA-- 658

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  771 dhQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEF 850
Cdd:COG1196   659 --GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE 736

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 665399881  851 AAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQE 892
Cdd:COG1196   737 LLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

810-1026

3.67e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 44.07 E-value: 3.67e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   810 AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEF-AAERDRLQSELRQRENEHQARRQEALREQEQELEQAKF 888
Cdd:TIGR02794   64 KKEQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAkQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERK 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   889 EMQERMAKQEEKYQNRVNTIEQQyQADFELWKTEHENKTKlaqaekenairqhyrAERDRQLDELVVRMEADALQHKEEH 968
Cdd:TIGR02794  144 AKEEAAKQAEEEAKAKAAAEAKK-KAEEAKKKAEAEAKAK---------------AEAEAKAKAEEAKAKAEAAKAKAAA 207

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 665399881   969 ELKMNRLKEKYEKDLVLAESVEKSLRekyAETRGKLAEADAQVRNSQAEVKQLQLELS 1026
Cdd:TIGR02794  208 EAAAKAEAEAAAAAAAEAERKADEAE---LGDIFGLASGSNAEKQGGARGAAAGSEVD 262

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

784-914

4.49e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.24 E-value: 4.49e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  784 QMQLLDA---LEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERF---ERQLEEEQRT--------QA--EQRQKLT 847
Cdd:COG3206   225 ESQLAEAraeLAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLaelEAELAELSARytpnhpdvIAlrAQIAALR 304

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665399881  848 EEFAAERDRLQSELRQrENEHQARRQEALREQEQELEQAKFEMQERMAKQEEkYQNRVNTIEQQYQA 914
Cdd:COG3206   305 AQLQQEAQRILASLEA-ELEALQAREASLQAQLAQLEARLAELPELEAELRR-LEREVEVARELYES 369

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

792-972

5.10e-04

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 44.17 E-value: 5.10e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   792 EEARTKHEQIETSIRESCAQDREAIIEKERTairERFERQLEEEQRTQAE------QRQKLTEEFAAERDRLQSELRQRE 865
Cdd:pfam15709  341 ERAEMRRLEVERKRREQEEQRRLQQEQLERA---EKMREELELEQQRRFEeirlrkQRLEEERQRQEEEERKQRLQLQAA 417

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   866 NEHQARRQEALREQEQELEQAKfemQERMAKQEEKYQNRVNTIEQQYQAdfelwktEHENKTKLAQAEKENAIRQHYRAE 945
Cdd:pfam15709  418 QERARQQQEEFRRKLQELQRKK---QQEEAERAEAEKQRQKELEMQLAE-------EQKRLMEMAEEERLEYQRQKQEAE 487

                          170       180
                   ....*....|....*....|....*..
gi 665399881   946 RDRQLdelvvrmEADALQHKEEHELKM 972
Cdd:pfam15709  488 EKARL-------EAEERRQKEEEAARL 507

growth_prot_Scy

NF041483

polarized growth protein Scy;

709-1021

5.25e-04

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 44.43 E-value: 5.25e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  709 TRRLESQNQAWEHRLETELARTkETTMAGEKIRRERwVRENTKKIKE--------LTVKGLEAE--INKMNCDHQR---E 775
Cdd:NF041483  433 AKTVELQEEARRLRGEAEQLRA-EAVAEGERIRGEA-RREAVQQIEEaartaeelLTKAKADADelRSTATAESERvrtE 510

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  776 VTELKRTHQMQLLDALEEARTKHEQIETsirESCAQDREAIIEKERTAirerfeRQLEEEQRTQAEQRQkltEEFAAERD 855
Cdd:NF041483  511 AIERATTLRRQAEETLERTRAEAERLRA---EAEEQAEEVRAAAERAA------RELREETERAIAARQ---AEAAEELT 578

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  856 RLQSELRQRenehQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKE 935
Cdd:NF041483  579 RLHTEAEER----LTAAEEALADARAEAERIRREAAEETERLRTEAAERIRTLQAQAEQEAERLRTEAAADASAARAEGE 654

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  936 NA---IRQHYRAERDRQLDELV-----VRMEADALQHK--EEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGK-- 1003
Cdd:NF041483  655 NVavrLRSEAAAEAERLKSEAQesadrVRAEAAAAAERvgTEAAEALAAAQEEAARRRREAEETLGSARAEADQERERar 734

                         330       340
                  ....*....|....*....|....
gi 665399881 1004 ------LAEADAQVRNSQAEVKQL 1021
Cdd:NF041483  735 eqseelLASARKRVEEAQAEAQRL 758

MAP7

pfam05672

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...

806-910

6.69e-04

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.

Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 41.56 E-value: 6.69e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   806 RESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQ---- 881
Cdd:pfam05672   27 REREEQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEERQRKAEEEAEEREQREQEEQERLQKQkeea 106

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 665399881   882 ------ELEQAKFEMQERMAKQEEKYQNRVNTIEQ 910
Cdd:pfam05672  107 eakareEAERQRQEREKIMQQEEQERLERKKRIEE 141

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

791-914

6.72e-04

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.95 E-value: 6.72e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  791 LEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRtqaEQRQKLTEEfaaERdRLQSELRQRENEHQA 870
Cdd:cd16269   176 LQSKEAEAEAILQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQR---ELEQKLEDQ---ER-SYEEHLRQLKEKMEE 248

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 665399881  871 RRQEALREQEQELEQakfEMQERMAKQEEKYQNRVNTIEQQYQA 914
Cdd:cd16269   249 ERENLLKEQERALES---KLKEQEALLEEGFKEQAELLQEEIRS 289

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

625-1025

7.10e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.77 E-value: 7.10e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  625 QLARRVIALSLRANELANAIHMSKEHvfqlRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEK 704
Cdd:COG1196   334 ELEEELEELEEELEEAEEELEEAEAE----LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  705 VAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQ 784
Cdd:COG1196   410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  785 MQLLDALEEARTKHEQIETSIRESCAQDREAII-----------EKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAE 853
Cdd:COG1196   490 AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  854 RD--------------RLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERM----AKQEEKYQNRVNTIEQQYQAD 915
Cdd:COG1196   570 KAgratflpldkirarAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGrtlvAARLEAALRRAVTLAGRLREV 649

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  916 FELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLRE 995
Cdd:COG1196   650 TLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 665399881  996 KYAETRGKLAE-----------------ADAQVRNSQAEVKQLQLEL 1025
Cdd:COG1196   730 LEAEREELLEElleeeelleeealeelpEPPDLEELERELERLEREI 776

GBP_C

pfam02841

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...

825-953

8.71e-04

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.

Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 42.66 E-value: 8.71e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   825 RERFERQLEEEQR--TQAEQ--RQKLTEEFAAERDRLQSE----LRQRENEHQARRQEALREQEQELEQAKFEMQERMAK 896
Cdd:pfam02841  157 RDKLEAKYNQVPRkgVKAEEvlQEFLQSKEAVEEAILQTDqaltAKEKAIEAERAKAEAAEAEQELLREKQKEEEQMMEA 236

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 665399881   897 QEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDEL 953
Cdd:pfam02841  237 QERSYQEHVKQLIEKMEAEREQLLAEQERMLEHKLQEQEELLKEGFKTEAESLQKEI 293

SMC_N

pfam02463

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

722-1084

9.25e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.42 E-value: 9.25e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   722 RLETELARTKETTMagEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDhQREVTELKRTHQMQLLDALEEARTKHEQI 801
Cdd:pfam02463  170 KKKEALKKLIEETE--NLAELIIDLEELKLQELKLKEQAKKALEYYQLKE-KLELEEEYLLYLDYLKLNEERIDLLQELL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   802 ETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERdrLQSELRQRENEHQARRQEALREQEQ 881
Cdd:pfam02463  247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK--SELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   882 ELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADA 961
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   962 LQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKyaetrgklaeaDAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDR 1041
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESI-----------ELKQGKLTEEKEELEKQELKLLKDELELKKSEDL 473

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 665399881  1042 LrdnlnadiQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIE 1084
Cdd:pfam02463  474 L--------KETQLVKLQEQLELLLSRQKLEERSQKESKARSG 508

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

903-1083

9.28e-04

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 43.67 E-value: 9.28e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  903 NRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA--IRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNrlkEKYE 980
Cdd:NF012221 1533 NVVATSESSQQADAVSKHAKQDDAAQNALADKERAeaDRQRLEQEKQQQLAA--ISGSQSQLESTDQNALETN---GQAQ 1607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  981 KDLVLAES--VEKSLREK---------YAETRGklaEADAQVRNSQAE--VKQLQLELSHSKKMCGDIIME-RDRLRDNL 1046
Cdd:NF012221 1608 RDAILEESraVTKELTTLaqgldaldsQATYAG---ESGDQWRNPFAGglLDRVQEQLDDAKKISGKQLADaKQRHVDNQ 1684

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 665399881 1047 ----NADIQSELGVLN-ERHKQEMDQ-LQKRVHQTIQRQEETI 1083
Cdd:NF012221 1685 qkvkDAVAKSEAGVAQgEQNQANAEQdIDDAKADAEKRKDDAL 1727

Caldesmon

pfam02029

Caldesmon;

657-902

9.85e-04

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 42.93 E-value: 9.85e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   657 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSlCEKVAALTRRLESQNQAW---EHRLETELARTKET 733
Cdd:pfam02029   84 ERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGR-YKEEETEIREKEYQENKWsteVRQAEEEGEEEEDK 162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   734 TMAGEKIRRERWVRENTKKI---KELTVKgleaEINKMNCDHQREVTELKrTHQMQLLDALEEARTKHEQIETSIRESCA 810
Cdd:pfam02029  163 SEEAEEVPTENFAKEEVKDEkikKEKKVK----YESKVFLDQKRGHPEVK-SQNGEEEVTKLKVTTKRRQGGLSQSQERE 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   811 QDREAIIEKERTAIRERFERQ-LEEEQRTQAEQRQKLTEEFAAERDRLQSELRQ-RENEHQARRQEALREQ---EQELEQ 885
Cdd:pfam02029  238 EEAEVFLEAEQKLEELRRRRQeKESEEFEKLRQKQQEAELELEELKKKREERRKlLEEEEQRRKQEEAERKlreEEEKRR 317

                          250
                   ....*....|....*..
gi 665399881   886 AKFEMQERMAKQEEKYQ 902
Cdd:pfam02029  318 MKEEIERRRAEAAEKRQ 334

PRK12704

phosphodiesterase; Provisional

751-915

9.94e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.23 E-value: 9.94e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  751 KKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQiETSIRESCAQDREA-IIEKErtairERFE 829
Cdd:PRK12704   26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEK-ELRERRNELQKLEKrLLQKE-----ENLD 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  830 RQLEEeqrtqAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQ----ELEQAKFEMQERMaKQEEKYQ--N 903
Cdd:PRK12704  100 RKLEL-----LEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERisglTAEEAKEILLEKV-EEEARHEaaV 173

                         170
                  ....*....|..
gi 665399881  904 RVNTIEQQYQAD 915
Cdd:PRK12704  174 LIKEIEEEAKEE 185

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

625-1024

1.01e-03

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.96 E-value: 1.01e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   625 QLARRVIALSLRANELANAIHMSKEHVFQLRgEKQKslraEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEK 704
Cdd:pfam07888   70 QWERQRRELESRVAELKEELRQSREKHEELE-EKYK----ELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQR 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   705 VaaLTRrlesqnqawehrlETELARTKETTmagEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQrevtELKRTHQ 784
Cdd:pfam07888  145 V--LER-------------ETELERMKERA---KKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ----ELRNSLA 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   785 MQLLDALeeaRTKHEQIETSIRESCAQDREAIIEKERTAIRERFERqLEEEQRTQAEQRQKLtEEFAAERDRLQSELrqr 864
Cdd:pfam07888  203 QRDTQVL---QLQDTITTLTQKLTTAHRKEAENEALLEELRSLQER-LNASERKVEGLGEEL-SSMAAQRDRTQAEL--- 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   865 eneHQARRQEAlrEQEQELEQAKFEMQERMAKqeekyqnrvntieqqyqadfelWKTEHENKTKLAQAEKEnairqhyra 944
Cdd:pfam07888  275 ---HQARLQAA--QLTLQLADASLALREGRAR----------------------WAQERETLQQSAEADKD--------- 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   945 eRDRQLDELVVRMEAdALQhkeehELKMNRLKEKYEkdlvLAESVEKSlREKYAETRGKLAEADAQVRNSQAEVKQLQLE 1024
Cdd:pfam07888  319 -RIEKLSAELQRLEE-RLQ-----EERMEREKLEVE----LGREKDCN-RVQLSESRRELQELKASLRVAQKEKEQLQAE 386

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

831-1081

1.27e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.18 E-value: 1.27e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   831 QLEEEQRTQAEQR----QKLTEEFAAERDRLqSELRQRENEHQARRQEALREQEQELEQAKF---EMQERMAKQEEKYQN 903
Cdd:pfam15921   99 ELHEKQKFYLRQSvidlQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHELEAAKClkeDMLEDSNTQIEQLRK 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   904 RVNTIEQQYQ------ADFELWKT----EHENKTKLAQAEKENAIRQHYRaERDRQLDELVVR----------------- 956
Cdd:pfam15921  178 MMLSHEGVLQeirsilVDFEEASGkkiyEHDSMSTMHFRSLGSAISKILR-ELDTEISYLKGRifpvedqlealksesqn 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   957 -MEADALQHKE-------EHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHS 1028
Cdd:pfam15921  257 kIELLLQQHQDrieqlisEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREA 336

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 665399881  1029 KKMCGDIIMERDRLRDNLNADIqSELGVLNERHKQEM----DQLQKRVHQTIQRQEE 1081
Cdd:pfam15921  337 KRMYEDKIEELEKQLVLANSEL-TEARTERDQFSQESgnldDQLQKLLADLHKREKE 392

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

840-1024

1.38e-03

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 42.14 E-value: 1.38e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   840 AEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEAlrEQEQELEQAKFEMQErmAKQEEkyQNRVNTIEQQYQADFELW 919
Cdd:TIGR02794   53 NRIQQQKKPAAKKEQERQKKLEQQAEEAEKQRAAEQ--ARQKELEQRAAAEKA--AKQAE--QAAKQAEEKQKQAEEAKA 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   920 KTEHENKtklAQAEKENAIRQHYRAERDRqldELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKyAE 999
Cdd:TIGR02794  127 KQAAEAK---AKAEAEAERKAKEEAAKQA---EEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAK-AE 199

                          170       180
                   ....*....|....*....|....*
gi 665399881  1000 TRGKLAEADAQVRNSQAEVKQLQLE 1024
Cdd:TIGR02794  200 AAKAKAAAEAAAKAEAEAAAAAAAE 224

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

758-1084

1.55e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 42.80 E-value: 1.55e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   758 VKGLEAEINKMNCDHQREVTELKRThQMQLLDALEEARTKHEQIeTSIRESCAQDREAIIEKERTAIRER-----FERQL 832
Cdd:pfam15921   87 VKDLQRRLNESNELHEKQKFYLRQS-VIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHELeaakcLKEDM 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   833 EEEQRTQAEQRQKLTEEFAAERDRLQSELRQREN-------EHQARR-----------QEALREQEQELEQAK---FEMQ 891
Cdd:pfam15921  165 LEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEasgkkiyEHDSMStmhfrslgsaiSKILRELDTEISYLKgriFPVE 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   892 ERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENK----TKLAQAEKENA---------IRQHYRAERD---RQLDEL-- 953
Cdd:pfam15921  245 DQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEitglTEKASSARSQAnsiqsqleiIQEQARNQNSmymRQLSDLes 324

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   954 -VVRMEADALQHKEEHELKMnrlkEKYEKDLVLAES---VEKSLREKYAETRGKLaeaDAQVRNSQAEV----KQLQLEL 1025
Cdd:pfam15921  325 tVSQLRSELREAKRMYEDKI----EELEKQLVLANSeltEARTERDQFSQESGNL---DDQLQKLLADLhkreKELSLEK 397

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665399881  1026 SHSKKM----CGDIIMeRDRLR---DNLNADIQsELGVLNERHKQEMDQLQKRVHQTIQRQEETIE 1084
Cdd:pfam15921  398 EQNKRLwdrdTGNSIT-IDHLRrelDDRNMEVQ-RLEALLKAMKSECQGQMERQMAAIQGKNESLE 461

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

791-1012

1.63e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 1.63e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  791 LEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFErQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQA 870
Cdd:COG3206   184 LPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLS-ELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQS 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  871 RRQEALREQEQELEQAKFEMQERMAKQEEKYQ---NRVNTIEQQYQAdfelwktehENKTKLAQAEKENAIRQHYRAERD 947
Cdd:COG3206   263 PVIQQLRAQLAELEAELAELSARYTPNHPDVIalrAQIAALRAQLQQ---------EAQRILASLEAELEALQAREASLQ 333

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665399881  948 RQLDELVVRMEADAlqhkeEHELKMNRLKEKYEkdlvLAESVEKSLREKYAETRGKLAEADAQVR 1012
Cdd:COG3206   334 AQLAQLEARLAELP-----ELEAELRRLEREVE----VARELYESLLQRLEEARLAEALTVGNVR 389

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

790-956

1.63e-03

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 42.14 E-value: 1.63e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   790 ALEEARTKHEQIETSIREScAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQ 869
Cdd:TIGR02794   79 EAEKQRAAEQARQKELEQR-AAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERKAKEEAAKQAEEEAK 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   870 ARRQEAlREQEQELEQAKFEmQERMAKQEEKYQNRVNtiEQQYQADFELWKTEHENKTKLAQAEKENAirqhyRAERDRQ 949
Cdd:TIGR02794  158 AKAAAE-AKKKAEEAKKKAE-AEAKAKAEAEAKAKAE--EAKAKAEAAKAKAAAEAAAKAEAEAAAAA-----AAEAERK 228


                   ....*..
gi 665399881   950 LDELVVR 956
Cdd:TIGR02794  229 ADEAELG 235

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

834-978

1.68e-03

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 42.25 E-value: 1.68e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   834 EEQRTQAEQRQKLT---EEFAAERDRL---QSELRQRENEHQARRQEALREQEQEleqaKFEMQERMAKQEEKYQNRV-- 905
Cdd:pfam15709  312 EEERSEEDPSKALLekrEQEKASRDRLraeRAEMRRLEVERKRREQEEQRRLQQE----QLERAEKMREELELEQQRRfe 387

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665399881   906 -NTIEQQYQADFELWKTEHENKTKLA-QAEKENAIRQhyRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEK 978
Cdd:pfam15709  388 eIRLRKQRLEEERQRQEEEERKQRLQlQAAQERARQQ--QEEFRRKLQELQRKKQQEEAERAEAEKQRQKELEMQ 460

PRK12705

hypothetical protein; Provisional

779-917

1.71e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.39 E-value: 1.71e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  779 LKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREaiiEKERTAIRERFERQLEEEQRTQAEQRQ--------KLTEEF 850
Cdd:PRK12705   31 LAKEAERILQEAQKEAEEKLEAALLEAKELLLRERN---QQRQEARREREELQREEERLVQKEEQLdaraekldNLENQL 107

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665399881  851 AAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERM-AKQEEKYQNRVNTIEQQYQADFE 917
Cdd:PRK12705  108 EEREKALSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLdAELEEEKAQRVKKIEEEADLEAE 175

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

632-1087

2.20e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 42.41 E-value: 2.20e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   632 ALSLRANELANAIHMSKEHVFQLrgekQKSLRAEKSTAAAKLrdqkkhyEEVVTRHQGFIEQLLKDKGSlceKVAALTRR 711
Cdd:pfam15921  221 AISKILRELDTEISYLKGRIFPV----EDQLEALKSESQNKI-------ELLLQQHQDRIEQLISEHEV---EITGLTEK 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   712 LESqnqawehrletelARTKETTMAGE-KIRRERWVRENTKKIKEL-----TVKGLEAEINKMNCDHQREVTELKRthQM 785
Cdd:pfam15921  287 ASS-------------ARSQANSIQSQlEIIQEQARNQNSMYMRQLsdlesTVSQLRSELREAKRMYEDKIEELEK--QL 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   786 QLLDA-LEEARTKHEQIEtsiRESCAQDREaiIEKERTAIRERferqlEEEQRTQAEQRQKLTEEFAAER---DRLQSEL 861
Cdd:pfam15921  352 VLANSeLTEARTERDQFS---QESGNLDDQ--LQKLLADLHKR-----EKELSLEKEQNKRLWDRDTGNSitiDHLRREL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   862 RQRENEHQarRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKT-------------- 927
Cdd:pfam15921  422 DDRNMEVQ--RLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTakkmtlessertvs 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   928 --KLAQAEKENAIR------QHYRAERDRQLDELV-VRMEADALQHKEEH----ELKMNR-------LKEKYEKDLVL-- 985
Cdd:pfam15921  500 dlTASLQEKERAIEatnaeiTKLRSRVDLKLQELQhLKNEGDHLRNVQTEcealKLQMAEkdkvieiLRQQIENMTQLvg 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881   986 -------AESVEKSLREK-YAETRGKLAE-------ADAQVRNSQAEVKQLQLEL-------SHSKKMCGDIIMERDRLR 1043
Cdd:pfam15921  580 qhgrtagAMQVEKAQLEKeINDRRLELQEfkilkdkKDAKIRELEARVSDLELEKvklvnagSERLRAVKDIKQERDQLL 659

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 665399881  1044 DNLNADiQSELGVLNErhkqEMDQLQKRVHQTIQRQEETIEILK 1087
Cdd:pfam15921  660 NEVKTS-RNELNSLSE----DYEVLKRNFRNKSEEMETTTNKLK 698

mukB

chromosome partition protein MukB;

823-955

2.71e-03

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.87 E-value: 2.71e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  823 AIRERFERQleEEQRTQAEQRQKLTEEFAAERDRLQSELRqreNEHQARRQEaLREQEQELE----QAKFEMQERMAKQE 898
Cdd:PRK04863  989 KLRQRLEQA--EQERTRAREQLRQAQAQLAQYNQVLASLK---SSYDAKRQM-LQELKQELQdlgvPADSGAEERARARR 1062

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 665399881  899 EKYQNRVNTIEQQyqadfelwKTEHENKTKLAQAEKENAIRQHYRAERD-RQLDELVV 955
Cdd:PRK04863 1063 DELHARLSANRSR--------RNQLEKQLTFCEAEMDNLTKKLRKLERDyHEMREQVV 1112

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

747-937

2.71e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.35 E-value: 2.71e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  747 RENTKKIKELT--VKGLEAEINKMncdhQREVTELKRTHQmQLLDALEEARTKHEQIETSIrescaQDREAIIEKERTAI 824
Cdd:COG3883    19 QAKQKELSELQaeLEAAQAELDAL----QAELEELNEEYN-ELQAELEALQAEIDKLQAEI-----AEAEAEIEERREEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665399881  825 RERFERQLEEEQ------------------------RTQAEQRQKLTEEFAAERDRLQSELRQRENEhqarrQEALREQE 880
Cdd:COG3883    89 GERARALYRSGGsvsyldvllgsesfsdfldrlsalSKIADADADLLEELKADKAELEAKKAELEAK-----LAELEALK 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 665399881  881 QELEQAKFEMQERMAKQEEKYqNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA 937
Cdd:COG3883   164 AELEAAKAELEAQQAEQEALL-AQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAA 219

MukB