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Conserved domains on  [gi|665404078|ref|NP_001285557|]
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phospholipase A2 activator protein, isoform C [Drosophila melanogaster]

Protein Classification

WD repeat PLAP family protein( domain architecture ID 10078051)

WD repeat PLAP family protein containing WD40, PFU, and PUL domains, similar to vertebrate phospholipase A-2-activating protein (PLAP or PLAA), a ubiquitin-binding protein involved in protein ubiquitination, sorting and degradation

CATH:  2.130.10.10
Gene Ontology:  GO:0005515|GO:0043130
PubMed:  10322433|8090199|30069656|29026209
SCOP:  4002744

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PFU pfam09070
PFU (PLAA family ubiquitin binding); This domain is found N terminal to pfam08324 and binds to ...
 353-462 3.70e-57

PFU (PLAA family ubiquitin binding); This domain is found N terminal to pfam08324 and binds to ubiquitin.


:

Pssm-ID: 462670  Cd Length: 111  Bit Score: 190.42  E-value: 3.70e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  353 GTREGQTKMVRHADGSVKCYTWTLGN--WNLVGDVTGATGgtqsNSGKKLHEGKEYDFVFSVDISDTEPPIKLPYNRSDD 430
Cdd:pfam09070   2 GKKEGQVKMVREGNGVVEAYQWSAAEqqWEKIGDVVGSAG----SSQKKEYEGKEYDYVFDVDIEDGKPPLKLPYNVGDN 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 665404078  431 PWQAAQTFIHRHSLPQAYLDQVANFIIKNSEG 462
Cdd:pfam09070  78 PYEAAQKFLARNELPQSYLDQVVNFIIKNTGG 109
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 10-305 1.38e-49

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


:

Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 176.37  E-value: 1.38e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  10 LSCELLGHSMDVRAVAVGPptpeGRQTILSGSRDKSTKVWKPHGNEYLesLTLQDHKNFISYICFLESERWICTASNDAT 89
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSP----DGKLLATGSGDGTIKVWDLETGELL--RTLKGHTGPVRDVAASADGTYLASGSSDKT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  90 ICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVSfvALEGHEAAVWAVATLKEQRKYVT 169
Cdd:cd00200   75 IRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLT--TLRGHTDWVNSVAFSPDGTFVAS 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 170 GGADRNIYYWNAKGEKL-RLLKGHTDCVRGVMGL-DANTLLSCGNDAVLRFWN-EDGECVREMNGHSNYIYSMARNEalG 246
Cdd:cd00200  153 SSQDGTIKLWDLRTGKCvATLTGHTGEVNSVAFSpDGEKLLSSSSDGTIKLWDlSTGKCLGTLRGHENGVNSVAFSP--D 230

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 247 DQVVVSCGEDSTLRMWNVITGDELGAPIIHPGiSVWSVTCLQNG-DIVTGCSDGVVRVFS 305
Cdd:cd00200  231 GYLLASGSEDGTIRVWDLRTGECVQTLSGHTN-SVTSLAWSPDGkRLASGSADGTIRIWD 289
PUL pfam08324
PUL domain; The PUL (PLAP, Ufd3p and Lub1p) domain is a novel alpha-helical Ub-associated ...
 531-781 7.91e-48

PUL domain; The PUL (PLAP, Ufd3p and Lub1p) domain is a novel alpha-helical Ub-associated domain. It directly binds to Cdc48, a chaperone-like AAA ATPase that collects ubiquitylated substrates.


:

Pssm-ID: 462428  Cd Length: 261  Bit Score: 170.21  E-value: 7.91e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  531 PVSNYRIFDTCDAKKVLEKMIEFNGK----LSLPDGRVgeEVLLAVIKLADQSPELDLTSLEAL-AILLKWPASMQFPVL 605
Cdd:pfam08324   1 PQKTYLSFKKANLDKILKKLGEFNGGepkvLALSPEEL--ATLEALLSFLESSSSASEADIELLlKILTSWPPEDRFPAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  606 DILRLAVRNEAIFSVLNNS--HNFLATVIPQLSGSA--PNQLMVVRCLANIMSHAAGRQNVMSRLAEIIDLVGAIKTGS- 680
Cdd:pfam08324  79 DLLRLLALDPRVAAYFAEEegGKTISTLLSLLISSGlyALRMLALRLLCNLFSSPLGRQLLLSHFDSILSTLASLLSSSl 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  681 ----ANLQIAVATFYLNLTISQT--LDVAKSEVCHVVTSGIVELLKW-AKDLEACYRSMQAIGNLTTTSCGQE--TIAQV 751
Cdd:pfam08324 159 ldsnKNLRIALATLLLNYAVLLHkeKSPLSEEDQVELLAALLEALSTeEEDSEALYRLLVALGTLVYAPDGEVlaDLAQV 238

                         250       260       270
                  ....*....|....*....|....*....|
gi 665404078  752 VSVDYVMDKLREltitpqdKNFSKVNSVGQ 781
Cdd:pfam08324 239 LDAASWVKKAKK-------KKEPRIKEVGS 261
 
Name Accession Description Interval E-value
PFU pfam09070
PFU (PLAA family ubiquitin binding); This domain is found N terminal to pfam08324 and binds to ...
 353-462 3.70e-57

PFU (PLAA family ubiquitin binding); This domain is found N terminal to pfam08324 and binds to ubiquitin.


Pssm-ID: 462670  Cd Length: 111  Bit Score: 190.42  E-value: 3.70e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  353 GTREGQTKMVRHADGSVKCYTWTLGN--WNLVGDVTGATGgtqsNSGKKLHEGKEYDFVFSVDISDTEPPIKLPYNRSDD 430
Cdd:pfam09070   2 GKKEGQVKMVREGNGVVEAYQWSAAEqqWEKIGDVVGSAG----SSQKKEYEGKEYDYVFDVDIEDGKPPLKLPYNVGDN 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 665404078  431 PWQAAQTFIHRHSLPQAYLDQVANFIIKNSEG 462
Cdd:pfam09070  78 PYEAAQKFLARNELPQSYLDQVVNFIIKNTGG 109
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 10-305 1.38e-49

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 176.37  E-value: 1.38e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  10 LSCELLGHSMDVRAVAVGPptpeGRQTILSGSRDKSTKVWKPHGNEYLesLTLQDHKNFISYICFLESERWICTASNDAT 89
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSP----DGKLLATGSGDGTIKVWDLETGELL--RTLKGHTGPVRDVAASADGTYLASGSSDKT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  90 ICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVSfvALEGHEAAVWAVATLKEQRKYVT 169
Cdd:cd00200   75 IRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLT--TLRGHTDWVNSVAFSPDGTFVAS 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 170 GGADRNIYYWNAKGEKL-RLLKGHTDCVRGVMGL-DANTLLSCGNDAVLRFWN-EDGECVREMNGHSNYIYSMARNEalG 246
Cdd:cd00200  153 SSQDGTIKLWDLRTGKCvATLTGHTGEVNSVAFSpDGEKLLSSSSDGTIKLWDlSTGKCLGTLRGHENGVNSVAFSP--D 230

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 247 DQVVVSCGEDSTLRMWNVITGDELGAPIIHPGiSVWSVTCLQNG-DIVTGCSDGVVRVFS 305
Cdd:cd00200  231 GYLLASGSEDGTIRVWDLRTGECVQTLSGHTN-SVTSLAWSPDGkRLASGSADGTIRIWD 289
PUL pfam08324
PUL domain; The PUL (PLAP, Ufd3p and Lub1p) domain is a novel alpha-helical Ub-associated ...
 531-781 7.91e-48

PUL domain; The PUL (PLAP, Ufd3p and Lub1p) domain is a novel alpha-helical Ub-associated domain. It directly binds to Cdc48, a chaperone-like AAA ATPase that collects ubiquitylated substrates.


Pssm-ID: 462428  Cd Length: 261  Bit Score: 170.21  E-value: 7.91e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  531 PVSNYRIFDTCDAKKVLEKMIEFNGK----LSLPDGRVgeEVLLAVIKLADQSPELDLTSLEAL-AILLKWPASMQFPVL 605
Cdd:pfam08324   1 PQKTYLSFKKANLDKILKKLGEFNGGepkvLALSPEEL--ATLEALLSFLESSSSASEADIELLlKILTSWPPEDRFPAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  606 DILRLAVRNEAIFSVLNNS--HNFLATVIPQLSGSA--PNQLMVVRCLANIMSHAAGRQNVMSRLAEIIDLVGAIKTGS- 680
Cdd:pfam08324  79 DLLRLLALDPRVAAYFAEEegGKTISTLLSLLISSGlyALRMLALRLLCNLFSSPLGRQLLLSHFDSILSTLASLLSSSl 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  681 ----ANLQIAVATFYLNLTISQT--LDVAKSEVCHVVTSGIVELLKW-AKDLEACYRSMQAIGNLTTTSCGQE--TIAQV 751
Cdd:pfam08324 159 ldsnKNLRIALATLLLNYAVLLHkeKSPLSEEDQVELLAALLEALSTeEEDSEALYRLLVALGTLVYAPDGEVlaDLAQV 238

                         250       260       270
                  ....*....|....*....|....*....|
gi 665404078  752 VSVDYVMDKLREltitpqdKNFSKVNSVGQ 781
Cdd:pfam08324 239 LDAASWVKKAKK-------KKEPRIKEVGS 261
WD40 COG2319
WD40 repeat [General function prediction only];
14-303 4.75e-46

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 169.71  E-value: 4.75e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  14 LLGHSMDVRAVAVgppTPEGrQTILSGSRDKSTKVWKPHGNEYLEslTLQDHKNFISYICFLESERWICTASNDATICIY 93
Cdd:COG2319  116 LTGHTGAVRSVAF---SPDG-KTLASGSADGTVRLWDLATGKLLR--TLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLW 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  94 KQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVSFvaLEGHEAAVWAVATLKEQRKYVTGGAD 173
Cdd:COG2319  190 DLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRT--LTGHSGSVRSVAFSPDGRLLASGSAD 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 174 RNIYYWNAK-GEKLRLLKGHTDCVRGV-MGLDANTLLSCGNDAVLRFWN-EDGECVREMNGHSNYIYSMARNEalGDQVV 250
Cdd:COG2319  268 GTVRLWDLAtGELLRTLTGHSGGVNSVaFSPDGKLLASGSDDGTVRLWDlATGKLLRTLTGHTGAVRSVAFSP--DGKTL 345

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 665404078 251 VSCGEDSTLRMWNVITGDELGAPIIHPGiSVWSVTCLQNGD-IVTGCSDGVVRV 303
Cdd:COG2319  346 ASGSDDGTVRLWDLATGELLRTLTGHTG-AVTSVAFSPDGRtLASGSADGTVRL 398
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 104-220 8.82e-07

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 52.78  E-value: 8.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 104 LKGHESTVCALS-AGLEPRSLISGSWDKTARVWTISEAGDVSFVALEgheAAVWAVATLKEQ-RKYVTGGADRNIYYWNA 181
Cdd:PLN00181 571 MKEHEKRVWSIDySSADPTLLASGSDDGSVKLWSINQGVSIGTIKTK---ANICCVQFPSESgRSLAFGSADHKVYYYDL 647

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 665404078 182 KGEKLRL--LKGHTDCVRGVMGLDANTLLSCGNDAVLRFWN 220
Cdd:PLN00181 648 RNPKLPLctMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWD 688
WD40 pfam00400
WD domain, G-beta repeat;
98-135 6.97e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.79  E-value: 6.97e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 665404078   98 FVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVW 135
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 222-263 1.63e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 39.60  E-value: 1.63e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 665404078   222 DGECVREMNGHSNYIYSMARNEalGDQVVVSCGEDSTLRMWN 263
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSP--DGKYLASGSDDGTIKLWD 40
 
Name Accession Description Interval E-value
PFU pfam09070
PFU (PLAA family ubiquitin binding); This domain is found N terminal to pfam08324 and binds to ...
 353-462 3.70e-57

PFU (PLAA family ubiquitin binding); This domain is found N terminal to pfam08324 and binds to ubiquitin.


Pssm-ID: 462670  Cd Length: 111  Bit Score: 190.42  E-value: 3.70e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  353 GTREGQTKMVRHADGSVKCYTWTLGN--WNLVGDVTGATGgtqsNSGKKLHEGKEYDFVFSVDISDTEPPIKLPYNRSDD 430
Cdd:pfam09070   2 GKKEGQVKMVREGNGVVEAYQWSAAEqqWEKIGDVVGSAG----SSQKKEYEGKEYDYVFDVDIEDGKPPLKLPYNVGDN 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 665404078  431 PWQAAQTFIHRHSLPQAYLDQVANFIIKNSEG 462
Cdd:pfam09070  78 PYEAAQKFLARNELPQSYLDQVVNFIIKNTGG 109
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 10-305 1.38e-49

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 176.37  E-value: 1.38e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  10 LSCELLGHSMDVRAVAVGPptpeGRQTILSGSRDKSTKVWKPHGNEYLesLTLQDHKNFISYICFLESERWICTASNDAT 89
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSP----DGKLLATGSGDGTIKVWDLETGELL--RTLKGHTGPVRDVAASADGTYLASGSSDKT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  90 ICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVSfvALEGHEAAVWAVATLKEQRKYVT 169
Cdd:cd00200   75 IRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLT--TLRGHTDWVNSVAFSPDGTFVAS 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 170 GGADRNIYYWNAKGEKL-RLLKGHTDCVRGVMGL-DANTLLSCGNDAVLRFWN-EDGECVREMNGHSNYIYSMARNEalG 246
Cdd:cd00200  153 SSQDGTIKLWDLRTGKCvATLTGHTGEVNSVAFSpDGEKLLSSSSDGTIKLWDlSTGKCLGTLRGHENGVNSVAFSP--D 230

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 247 DQVVVSCGEDSTLRMWNVITGDELGAPIIHPGiSVWSVTCLQNG-DIVTGCSDGVVRVFS 305
Cdd:cd00200  231 GYLLASGSEDGTIRVWDLRTGECVQTLSGHTN-SVTSLAWSPDGkRLASGSADGTIRIWD 289
PUL pfam08324
PUL domain; The PUL (PLAP, Ufd3p and Lub1p) domain is a novel alpha-helical Ub-associated ...
 531-781 7.91e-48

PUL domain; The PUL (PLAP, Ufd3p and Lub1p) domain is a novel alpha-helical Ub-associated domain. It directly binds to Cdc48, a chaperone-like AAA ATPase that collects ubiquitylated substrates.


Pssm-ID: 462428  Cd Length: 261  Bit Score: 170.21  E-value: 7.91e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  531 PVSNYRIFDTCDAKKVLEKMIEFNGK----LSLPDGRVgeEVLLAVIKLADQSPELDLTSLEAL-AILLKWPASMQFPVL 605
Cdd:pfam08324   1 PQKTYLSFKKANLDKILKKLGEFNGGepkvLALSPEEL--ATLEALLSFLESSSSASEADIELLlKILTSWPPEDRFPAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  606 DILRLAVRNEAIFSVLNNS--HNFLATVIPQLSGSA--PNQLMVVRCLANIMSHAAGRQNVMSRLAEIIDLVGAIKTGS- 680
Cdd:pfam08324  79 DLLRLLALDPRVAAYFAEEegGKTISTLLSLLISSGlyALRMLALRLLCNLFSSPLGRQLLLSHFDSILSTLASLLSSSl 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  681 ----ANLQIAVATFYLNLTISQT--LDVAKSEVCHVVTSGIVELLKW-AKDLEACYRSMQAIGNLTTTSCGQE--TIAQV 751
Cdd:pfam08324 159 ldsnKNLRIALATLLLNYAVLLHkeKSPLSEEDQVELLAALLEALSTeEEDSEALYRLLVALGTLVYAPDGEVlaDLAQV 238

                         250       260       270
                  ....*....|....*....|....*....|
gi 665404078  752 VSVDYVMDKLREltitpqdKNFSKVNSVGQ 781
Cdd:pfam08324 239 LDAASWVKKAKK-------KKEPRIKEVGS 261
WD40 COG2319
WD40 repeat [General function prediction only];
14-303 4.75e-46

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 169.71  E-value: 4.75e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  14 LLGHSMDVRAVAVgppTPEGrQTILSGSRDKSTKVWKPHGNEYLEslTLQDHKNFISYICFLESERWICTASNDATICIY 93
Cdd:COG2319  116 LTGHTGAVRSVAF---SPDG-KTLASGSADGTVRLWDLATGKLLR--TLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLW 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  94 KQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVSFvaLEGHEAAVWAVATLKEQRKYVTGGAD 173
Cdd:COG2319  190 DLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRT--LTGHSGSVRSVAFSPDGRLLASGSAD 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 174 RNIYYWNAK-GEKLRLLKGHTDCVRGV-MGLDANTLLSCGNDAVLRFWN-EDGECVREMNGHSNYIYSMARNEalGDQVV 250
Cdd:COG2319  268 GTVRLWDLAtGELLRTLTGHSGGVNSVaFSPDGKLLASGSDDGTVRLWDlATGKLLRTLTGHTGAVRSVAFSP--DGKTL 345

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 665404078 251 VSCGEDSTLRMWNVITGDELGAPIIHPGiSVWSVTCLQNGD-IVTGCSDGVVRV 303
Cdd:COG2319  346 ASGSDDGTVRLWDLATGELLRTLTGHTG-AVTSVAFSPDGRtLASGSADGTVRL 398
WD40 COG2319
WD40 repeat [General function prediction only];
14-305 1.61e-42

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 159.69  E-value: 1.61e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  14 LLGHSMDVRAVAVGPPtpegRQTILSGSRDKSTKVWKPHGNEYLesLTLQDHKNFISYICFLESERWICTASNDATICIY 93
Cdd:COG2319   74 LLGHTAAVLSVAFSPD----GRLLASASADGTVRLWDLATGLLL--RTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLW 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  94 KQDGFVPLLTLKGHESTV--CALSA-GlepRSLISGSWDKTARVWTISEAGDVSfvALEGHEAAVWAVATLKEQRKYVTG 170
Cdd:COG2319  148 DLATGKLLRTLTGHSGAVtsVAFSPdG---KLLASGSDDGTVRLWDLATGKLLR--TLTGHTGAVRSVAFSPDGKLLASG 222

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 171 GADRNIYYWNAK-GEKLRLLKGHTDCVRGV-MGLDANTLLSCGNDAVLRFWN-EDGECVREMNGHSNYIYSMARneALGD 247
Cdd:COG2319  223 SADGTVRLWDLAtGKLLRTLTGHSGSVRSVaFSPDGRLLASGSADGTVRLWDlATGELLRTLTGHSGGVNSVAF--SPDG 300

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 665404078 248 QVVVSCGEDSTLRMWNVITGDELGAPIIHPGiSVWSVTCLQNGD-IVTGCSDGVVRVFS 305
Cdd:COG2319  301 KLLASGSDDGTVRLWDLATGKLLRTLTGHTG-AVRSVAFSPDGKtLASGSDDGTVRLWD 358
WD40 COG2319
WD40 repeat [General function prediction only];
4-264 1.19e-39

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 151.60  E-value: 1.19e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078   4 SLDNYKLSCELLGHSMDVRAVAVgppTPEGRqTILSGSRDKSTKVWKPHGNEYLEslTLQDHKNFISYICFLESERWICT 83
Cdd:COG2319  148 DLATGKLLRTLTGHSGAVTSVAF---SPDGK-LLASGSDDGTVRLWDLATGKLLR--TLTGHTGAVRSVAFSPDGKLLAS 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  84 ASNDATICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTIseAGDVSFVALEGHEAAVWAVATLKE 163
Cdd:COG2319  222 GSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDL--ATGELLRTLTGHSGGVNSVAFSPD 299

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 164 QRKYVTGGADRNIYYWNAK-GEKLRLLKGHTDCVRGV-MGLDANTLLSCGNDAVLRFWN-EDGECVREMNGHSNYIYSMA 240
Cdd:COG2319  300 GKLLASGSDDGTVRLWDLAtGKLLRTLTGHTGAVRSVaFSPDGKTLASGSDDGTVRLWDlATGELLRTLTGHTGAVTSVA 379

                        250       260
                 ....*....|....*....|....*
gi 665404078 241 rneALGD-QVVVSCGEDSTLRMWNV 264
Cdd:COG2319  380 ---FSPDgRTLASGSADGTVRLWDL 401
WD40 COG2319
WD40 repeat [General function prediction only];
14-305 3.16e-38

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 147.37  E-value: 3.16e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  14 LLGHSMDVRAVAVGPPtpegRQTILSGSRDKSTKVWKPHGNEylESLTLQDHKNFISYICFLESERWICTASNDATICIY 93
Cdd:COG2319   32 LLGLAAAVASLAASPD----GARLAAGAGDLTLLLLDAAAGA--LLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLW 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  94 KQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVSfvALEGHEAAVWAVATLKEQRKYVTGGAD 173
Cdd:COG2319  106 DLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLR--TLTGHSGAVTSVAFSPDGKLLASGSDD 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 174 RNIYYWNAK-GEKLRLLKGHTDCVRGV-MGLDANTLLSCGNDAVLRFWN-EDGECVREMNGHSNYIYSMARNeaLGDQVV 250
Cdd:COG2319  184 GTVRLWDLAtGKLLRTLTGHTGAVRSVaFSPDGKLLASGSADGTVRLWDlATGKLLRTLTGHSGSVRSVAFS--PDGRLL 261

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 665404078 251 VSCGEDSTLRMWNVITGDELGAPIIHPGiSVWSVTCLQNGD-IVTGCSDGVVRVFS 305
Cdd:COG2319  262 ASGSADGTVRLWDLATGELLRTLTGHSG-GVNSVAFSPDGKlLASGSDDGTVRLWD 316
WD40 COG2319
WD40 repeat [General function prediction only];
57-305 7.68e-32

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 128.49  E-value: 7.68e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  57 LESLTLQDHKNFISYICFLESERWICTASNDATICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWT 136
Cdd:COG2319   27 ALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWD 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 137 ISEAGDVsfVALEGHEAAVWAVATLKEQRKYVTGGADRNIYYWNAK-GEKLRLLKGHTDCVRGV-MGLDANTLLSCGNDA 214
Cdd:COG2319  107 LATGLLL--RTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLAtGKLLRTLTGHSGAVTSVaFSPDGKLLASGSDDG 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 215 VLRFWN-EDGECVREMNGHSNYIYSMA--RNealgDQVVVSCGEDSTLRMWNVITGDELgAPIIHPGISVWSVTCLQNGD 291
Cdd:COG2319  185 TVRLWDlATGKLLRTLTGHTGAVRSVAfsPD----GKLLASGSADGTVRLWDLATGKLL-RTLTGHSGSVRSVAFSPDGR 259

                        250
                 ....*....|....*
gi 665404078 292 -IVTGCSDGVVRVFS 305
Cdd:COG2319  260 lLASGSADGTVRLWD 274
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 103-306 6.38e-30

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 120.13  E-value: 6.38e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 103 TLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISeaGDVSFVALEGHEAAVWAVATLKEQRKYVTGGADRNIYYWNA- 181
Cdd:cd00200    4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLE--TGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLe 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 182 KGEKLRLLKGHTDCVRGVMGLDANTLL-SCGNDAVLRFWN-EDGECVREMNGHSNYIYSMARNEalGDQVVVSCGEDSTL 259
Cdd:cd00200   82 TGECVRTLTGHTSYVSSVAFSPDGRILsSSSRDKTIKVWDvETGKCLTTLRGHTDWVNSVAFSP--DGTFVASSSQDGTI 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 665404078 260 RMWNVITGDELGAPIIHPGiSVWSVTCLQNG-DIVTGCSDGVVRVFSH 306
Cdd:cd00200  160 KLWDLRTGKCVATLTGHTG-EVNSVAFSPDGeKLLSSSSDGTIKLWDL 206
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 4-220 2.22e-29

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 118.59  E-value: 2.22e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078   4 SLDNYKLSCELLGHSMDVRAVAVGPptpeGRQTILSGSRDKSTKVWkpHGNEYLESLTLQDHKNFISYICFLESERWICT 83
Cdd:cd00200   79 DLETGECVRTLTGHTSYVSSVAFSP----DGRILSSSSRDKTIKVW--DVETGKCLTTLRGHTDWVNSVAFSPDGTFVAS 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  84 ASNDATICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAgdvSFVA-LEGHEAAVWAVATLK 162
Cdd:cd00200  153 SSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTG---KCLGtLRGHENGVNSVAFSP 229

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 163 EQRKYVTGGADRNIYYWN-AKGEKLRLLKGHTDCVRGVMGL-DANTLLSCGNDAVLRFWN 220
Cdd:cd00200  230 DGYLLASGSEDGTIRVWDlRTGECVQTLSGHTNSVTSLAWSpDGKRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
4-183 1.26e-25

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 110.00  E-value: 1.26e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078   4 SLDNYKLSCELLGHSMDVRAVAVgppTPEGrQTILSGSRDKSTKVWKPHGNEYLEslTLQDHKNFISYICFLESERWICT 83
Cdd:COG2319  232 DLATGKLLRTLTGHSGSVRSVAF---SPDG-RLLASGSADGTVRLWDLATGELLR--TLTGHSGGVNSVAFSPDGKLLAS 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078  84 ASNDATICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVsfVALEGHEAAVWAVATLKE 163
Cdd:COG2319  306 GSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELL--RTLTGHTGAVTSVAFSPD 383

                        170       180
                 ....*....|....*....|
gi 665404078 164 QRKYVTGGADRNIYYWNAKG 183
Cdd:COG2319  384 GRTLASGSADGTVRLWDLAT 403
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 104-220 8.82e-07

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 52.78  E-value: 8.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 104 LKGHESTVCALS-AGLEPRSLISGSWDKTARVWTISEAGDVSFVALEgheAAVWAVATLKEQ-RKYVTGGADRNIYYWNA 181
Cdd:PLN00181 571 MKEHEKRVWSIDySSADPTLLASGSDDGSVKLWSINQGVSIGTIKTK---ANICCVQFPSESgRSLAFGSADHKVYYYDL 647

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 665404078 182 KGEKLRL--LKGHTDCVRGVMGLDANTLLSCGNDAVLRFWN 220
Cdd:PLN00181 648 RNPKLPLctMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWD 688
WD40 COG2319
WD40 repeat [General function prediction only];
179-305 1.37e-06

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 51.45  E-value: 1.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404078 179 WNAKGEKLRLLKGHTDCVRGVMG--LDANTLLSCGNDAVLRFWNEDGECVREMNGHSNYIYSMARneALGDQVVVSCGED 256
Cdd:COG2319   22 AAALGALLLLLLGLAAAVASLAAspDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAF--SPDGRLLASASAD 99

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 665404078 257 STLRMWNVITGDELGAPIIHPGiSVWSVTCLQNGD-IVTGCSDGVVRVFS 305
Cdd:COG2319  100 GTVRLWDLATGLLLRTLTGHTG-AVRSVAFSPDGKtLASGSADGTVRLWD 148
WD40 pfam00400
WD domain, G-beta repeat;
98-135 6.97e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.79  E-value: 6.97e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 665404078   98 FVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVW 135
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 222-263 1.63e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 39.60  E-value: 1.63e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 665404078   222 DGECVREMNGHSNYIYSMARNEalGDQVVVSCGEDSTLRMWN 263
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSP--DGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
223-263 2.84e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 38.87  E-value: 2.84e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 665404078  223 GECVREMNGHSNYIYSMARNEalGDQVVVSCGEDSTLRMWN 263
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSP--DGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 98-135 1.28e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 36.91  E-value: 1.28e-03
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 665404078    98 FVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVW 135
Cdd:smart00320   2 GELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 61-94 2.26e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 36.52  E-value: 2.26e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 665404078    61 TLQDHKNFISYICFLESERWICTASNDATICIYK 94
Cdd:smart00320   7 TLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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