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Conserved domains on  [gi|663071149|ref|NP_001284667|]
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tubulin-specific chaperone A isoform 1 [Homo sapiens]

Protein Classification

tubulin-specific chaperone A( domain architecture ID 10503071)

tubulin-specific chaperone A (TBCA) is a tubulin-folding protein similar to human TBCA which interacts with beta-tubulin and is involved in the folding and dimerization of new tubulin heterodimers, the building blocks of microtubules

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TBCA pfam02970
Tubulin binding cofactor A;
4-84 3.47e-35

Tubulin binding cofactor A;


:

Pssm-ID: 460769 [Multi-domain]  Cd Length: 99  Bit Score: 116.84  E-value: 3.47e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663071149    4 PRVRQIKIKTGVVKRLVKEKVMYEKEAKQQEEKIEKMRAEDGENYDIKKQAEILQESRMMIPDCQRRLEAAYLDLQRILV 83
Cdd:pfam02970   1 PRPRQLKIKTGVVKRLVKEEASYEKELEEQEARLEKLKADGADEYDLKKQEEVLEETKAMIPDLKKRLEEAVEDLEEFLE 80


                  .
gi 663071149   84 S 84
Cdd:pfam02970  81 E 81
 
Name Accession Description Interval E-value
TBCA pfam02970
Tubulin binding cofactor A;
4-84 3.47e-35

Tubulin binding cofactor A;


Pssm-ID: 460769 [Multi-domain]  Cd Length: 99  Bit Score: 116.84  E-value: 3.47e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663071149    4 PRVRQIKIKTGVVKRLVKEKVMYEKEAKQQEEKIEKMRAEDGENYDIKKQAEILQESRMMIPDCQRRLEAAYLDLQRILV 83
Cdd:pfam02970   1 PRPRQLKIKTGVVKRLVKEEASYEKELEEQEARLEKLKADGADEYDLKKQEEVLEETKAMIPDLKKRLEEAVEDLEEFLE 80


                  .
gi 663071149   84 S 84
Cdd:pfam02970  81 E 81
 
Name Accession Description Interval E-value
TBCA pfam02970
Tubulin binding cofactor A;
4-84 3.47e-35

Tubulin binding cofactor A;


Pssm-ID: 460769 [Multi-domain]  Cd Length: 99  Bit Score: 116.84  E-value: 3.47e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663071149    4 PRVRQIKIKTGVVKRLVKEKVMYEKEAKQQEEKIEKMRAEDGENYDIKKQAEILQESRMMIPDCQRRLEAAYLDLQRILV 83
Cdd:pfam02970   1 PRPRQLKIKTGVVKRLVKEEASYEKELEEQEARLEKLKADGADEYDLKKQEEVLEETKAMIPDLKKRLEEAVEDLEEFLE 80


                  .
gi 663071149   84 S 84
Cdd:pfam02970  81 E 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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