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Conserved domains on  [gi|576796148|ref|NP_001276707|]
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MAP7 domain-containing protein 2 [Rattus norvegicus]

Protein Classification

MAP7 domain-containing protein( domain architecture ID 12064852)

MAP7 domain-containing protein such as MAP7D1 (microtubule-associated protein 7 domain containing 1) identified as a novel substrate of doublecortin-like kinase 1 (DCLK1)

Gene Ontology:  GO:0005737

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 422-588 2.51e-19

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


:

Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 85.48  E-value: 2.51e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148  422 KSTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEEQERLEKEELKRKAEEERLRIEKQEEEKKQQEEEEKRKAEEK 501
Cdd:pfam05672   1 KPSAGTTDAEEAARILAEKRRQAREQREREEQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEERQRK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148  502 AKEKAEEELLSKEEQEKekqekekkekamiekQIQAEKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKR 581
Cdd:pfam05672  81 AEEEAEEREQREQEEQE---------------RLQKQKEEAEAKAREEAERQRQEREKIMQQEEQERLERKKRIEEIMKR 145


                  ....*..
gi 576796148  582 TRKSDAS 588
Cdd:pfam05672 146 TRKSDQA 152
DUF5401 super family cl38662
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 57-150 4.19e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


The actual alignment was detected with superfamily member pfam17380:

Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.12  E-value: 4.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   57 ERQRLAKERREEREKCLAAREQQILEKQKRAKLqYEKQIEERWRKLEEqrqrEDQKRAAVEEKRKQKLREEEERLEAMMR 136
Cdd:pfam17380 485 DRKRAEEQRRKILEKELEERKQAMIEEERKRKL-LEKEMEERQKAIYE----EERRREAEEERRKQQEMEERRRIQEQMR 559

                          90
                  ....*....|....
gi 576796148  137 RSLERTQQLELKKK 150
Cdd:pfam17380 560 KATEERSRLEAMER 573
 
Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 422-588 2.51e-19

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 85.48  E-value: 2.51e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148  422 KSTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEEQERLEKEELKRKAEEERLRIEKQEEEKKQQEEEEKRKAEEK 501
Cdd:pfam05672   1 KPSAGTTDAEEAARILAEKRRQAREQREREEQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEERQRK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148  502 AKEKAEEELLSKEEQEKekqekekkekamiekQIQAEKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKR 581
Cdd:pfam05672  81 AEEEAEEREQREQEEQE---------------RLQKQKEEAEAKAREEAERQRQEREKIMQQEEQERLERKKRIEEIMKR 145


                  ....*..
gi 576796148  582 TRKSDAS 588
Cdd:pfam05672 146 TRKSDQA 152
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 57-150 4.19e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.12  E-value: 4.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   57 ERQRLAKERREEREKCLAAREQQILEKQKRAKLqYEKQIEERWRKLEEqrqrEDQKRAAVEEKRKQKLREEEERLEAMMR 136
Cdd:pfam17380 485 DRKRAEEQRRKILEKELEERKQAMIEEERKRKL-LEKEMEERQKAIYE----EERRREAEEERRKQQEMEERRRIQEQMR 559

                          90
                  ....*....|....
gi 576796148  137 RSLERTQQLELKKK 150
Cdd:pfam17380 560 KATEERSRLEAMER 573
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 57-150 1.33e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 41.75  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   57 ERQRLAKERREEREkclaAREQQILEKQKRAKLQYEKQIEERWRKLEEQR-QREDQKRAAVEEKRKQKLREEEERLEAMM 135
Cdd:TIGR02794  66 EQERQKKLEQQAEE----AEKQRAAEQARQKELEQRAAAEKAAKQAEQAAkQAEEKQKQAEEAKAKQAAEAKAKAEAEAE 141

                          90
                  ....*....|....*.
gi 576796148  136 RRSLERTQ-QLELKKK 150
Cdd:TIGR02794 142 RKAKEEAAkQAEEEAK 157
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
57-146 4.40e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 4.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148  57 ERQRLAKERREEREKCLAAREQQILEKQKRAKLQyekQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMR 136
Cdd:COG4717  109 AELEELREELEKLEKLLQLLPLYQELEALEAELA---ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQ 185

                         90
                 ....*....|
gi 576796148 137 RSLERTQQLE 146
Cdd:COG4717  186 LSLATEEELQ 195
PTZ00121 PTZ00121
MAEBL; Provisional
 54-150 4.47e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 4.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   54 KSDERQRLAKE-RREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLE 132
Cdd:PTZ00121 1641 KEAEEKKKAEElKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEE 1720

                          90
                  ....*....|....*...
gi 576796148  133 AMMRRSLERTQQLELKKK 150
Cdd:PTZ00121 1721 LKKAEEENKIKAEEAKKE 1738
 
Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 422-588 2.51e-19

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 85.48  E-value: 2.51e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148  422 KSTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEEQERLEKEELKRKAEEERLRIEKQEEEKKQQEEEEKRKAEEK 501
Cdd:pfam05672   1 KPSAGTTDAEEAARILAEKRRQAREQREREEQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEERQRK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148  502 AKEKAEEELLSKEEQEKekqekekkekamiekQIQAEKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKR 581
Cdd:pfam05672  81 AEEEAEEREQREQEEQE---------------RLQKQKEEAEAKAREEAERQRQEREKIMQQEEQERLERKKRIEEIMKR 145


                  ....*..
gi 576796148  582 TRKSDAS 588
Cdd:pfam05672 146 TRKSDQA 152
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 57-150 4.19e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.12  E-value: 4.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   57 ERQRLAKERREEREKCLAAREQQILEKQKRAKLqYEKQIEERWRKLEEqrqrEDQKRAAVEEKRKQKLREEEERLEAMMR 136
Cdd:pfam17380 485 DRKRAEEQRRKILEKELEERKQAMIEEERKRKL-LEKEMEERQKAIYE----EERRREAEEERRKQQEMEERRRIQEQMR 559

                          90
                  ....*....|....
gi 576796148  137 RSLERTQQLELKKK 150
Cdd:pfam17380 560 KATEERSRLEAMER 573
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 57-144 5.65e-04

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 41.18  E-value: 5.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   57 ERQRLAKERREEREKclaAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAvEEKRKQKLREEEERLEAMMR 136
Cdd:pfam05672  18 EKRRQAREQREREEQ---ERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRRE-EEERQRKAEEEAEEREQREQ 93


                  ....*...
gi 576796148  137 RSLERTQQ 144
Cdd:pfam05672  94 EEQERLQK 101
ARGLU pfam15346
Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is ...
 57-150 8.03e-04

Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is required for the oestrogen-dependent expression of ESR1 target genes. It functions in cooperation with MED1. The family of proteins is found in eukaryotes.


Pssm-ID: 405931 [Multi-domain]  Cd Length: 151  Bit Score: 40.42  E-value: 8.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   57 ERQRLAKERRE--EREKCLAAREQQILEKQKRAKLQ-YEKQIEERWRKLEE-QRQREDQKRAAVEEKRKQKlrEEEERLE 132
Cdd:pfam15346  46 ARKIMEKQVLEelEREREAELEEERRKEEEERKKREeLERILEENNRKIEEaQRKEAEERLAMLEEQRRMK--EERQRRE 123

                          90
                  ....*....|....*...
gi 576796148  133 AMMRRSLERTQQLELKKK 150
Cdd:pfam15346 124 KEEEEREKREQQKILNKK 141
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 57-150 1.33e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 41.75  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   57 ERQRLAKERREEREkclaAREQQILEKQKRAKLQYEKQIEERWRKLEEQR-QREDQKRAAVEEKRKQKLREEEERLEAMM 135
Cdd:TIGR02794  66 EQERQKKLEQQAEE----AEKQRAAEQARQKELEQRAAAEKAAKQAEQAAkQAEEKQKQAEEAKAKQAAEAKAKAEAEAE 141

                          90
                  ....*....|....*.
gi 576796148  136 RRSLERTQ-QLELKKK 150
Cdd:TIGR02794 142 RKAKEEAAkQAEEEAK 157
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 56-123 1.38e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 41.44  E-value: 1.38e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 576796148   56 DERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQK 123
Cdd:pfam13868  58 EEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQ 125
DDRGK pfam09756
DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and ...
 54-123 2.42e-03

DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


Pssm-ID: 370664 [Multi-domain]  Cd Length: 188  Bit Score: 39.64  E-value: 2.42e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   54 KSDERQRLAKERREEREKclaarEQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQK 123
Cdd:pfam09756   6 KKRAKLELKEAKRQQREA-----EEEEREEREKLEEKREEEYKEREEREEEAEKEKEEEERKQEEEQERK 70
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 56-122 3.17e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 40.29  E-value: 3.17e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   56 DERQRLAKERREEREKCLA---AREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQ 122
Cdd:pfam13868  40 EEERRLDEMMEEERERALEeeeEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVER 109
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
57-146 4.40e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 4.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148  57 ERQRLAKERREEREKCLAAREQQILEKQKRAKLQyekQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMR 136
Cdd:COG4717  109 AELEELREELEKLEKLLQLLPLYQELEALEAELA---ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQ 185

                         90
                 ....*....|
gi 576796148 137 RSLERTQQLE 146
Cdd:COG4717  186 LSLATEEELQ 195
PTZ00121 PTZ00121
MAEBL; Provisional
 54-150 4.47e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 4.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   54 KSDERQRLAKE-RREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLE 132
Cdd:PTZ00121 1641 KEAEEKKKAEElKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEE 1720

                          90
                  ....*....|....*...
gi 576796148  133 AMMRRSLERTQQLELKKK 150
Cdd:PTZ00121 1721 LKKAEEENKIKAEEAKKE 1738
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 57-150 5.88e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.11  E-value: 5.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   57 ERQRLAKERREEREkclAAREQQILEKQKRAKLQYEKQI------------EERWRKLEEQRQREDQKRAAVEEKRKQKL 124
Cdd:pfam17380 386 ERQQKNERVRQELE---AARKVKILEEERQRKIQQQKVEmeqiraeqeearQREVRRLEEERAREMERVRLEEQERQQQV 462

                          90       100
                  ....*....|....*....|....*.
gi 576796148  125 REEEERLEAMMRRSLERTQQLELKKK 150
Cdd:pfam17380 463 ERLRQQEEERKRKKLELEKEKRDRKR 488
PTZ00121 PTZ00121
MAEBL; Provisional
 54-150 7.55e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.12  E-value: 7.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   54 KSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEA 133
Cdd:PTZ00121 1451 KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                          90
                  ....*....|....*..
gi 576796148  134 MMRRSLERTQQLELKKK 150
Cdd:PTZ00121 1531 EEAKKADEAKKAEEKKK 1547
PTZ00121 PTZ00121
MAEBL; Provisional
 60-149 7.81e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 7.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   60 RLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSL 139
Cdd:PTZ00121 1662 KAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741

                          90
                  ....*....|
gi 576796148  140 ERTQQLELKK 149
Cdd:PTZ00121 1742 DKKKAEEAKK 1751
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 54-123 7.87e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 39.72  E-value: 7.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   54 KSDERQRLAKERREEREKCLAA---REQQIL------EKQKRAKLQYEKQIEERWRKLEEQR-----QREDQKRAAVEEK 119
Cdd:pfam17380 433 RQREVRRLEEERAREMERVRLEeqeRQQQVErlrqqeEERKRKKLELEKEKRDRKRAEEQRRkilekELEERKQAMIEEE 512


                  ....
gi 576796148  120 RKQK 123
Cdd:pfam17380 513 RKRK 516
rne PRK10811
ribonuclease E; Reviewed
 57-185 8.23e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 39.64  E-value: 8.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   57 ERQRlaKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERwrkLEEQRQREDQKRAA--------VEEKRKQKLREEE 128
Cdd:PRK10811  637 EENR--RNRRQAQQQTAETRESQQAEVTEKARTQDEQQQAPR---RERQRRRNDEKRQAqqeakalnVEEQSVQETEQEE 711

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 576796148  129 ERLEAMMRRslertQQLELKKKCSwAGSAASGPGGRDGESENTPPLPLTLAASIPPS 185
Cdd:PRK10811  712 RVQQVQPRR-----KQRQLNQKVR-IEQSVAEEAVAPVVEETVAAEPVVQEVPAPRT 762
PTZ00121 PTZ00121
MAEBL; Provisional
 54-146 9.26e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 9.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576796148   54 KSDERQRLAKERREEREKCLAAREQQILEK--QKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERL 131
Cdd:PTZ00121 1559 KAEEKKKAEEAKKAEEDKNMALRKAEEAKKaeEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQL 1638

                          90
                  ....*....|....*
gi 576796148  132 EAMMRRSLERTQQLE 146
Cdd:PTZ00121 1639 KKKEAEEKKKAEELK 1653
DDRGK pfam09756
DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and ...
 58-111 9.77e-03

DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


Pssm-ID: 370664 [Multi-domain]  Cd Length: 188  Bit Score: 38.10  E-value: 9.77e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 576796148   58 RQRLAKER-REEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQ 111
Cdd:pfam09756  19 QQREAEEEeREEREKLEEKREEEYKEREEREEEAEKEKEEEERKQEEEQERKEQE 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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