|
Name |
Accession |
Description |
Interval |
E-value |
| GT4_ALG11-like |
cd03806 |
alpha-1,2-mannosyltransferase ALG11 and similar proteins; This family is most closely related ... |
33-457 |
0e+00 |
|
alpha-1,2-mannosyltransferase ALG11 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides.
Pssm-ID: 340835 [Multi-domain] Cd Length: 419 Bit Score: 734.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 33 AVAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEILDGARRRFNIRLPRPVKFVF-LKHRLLVEAK 111
Cdd:cd03806 2 TVGFFHPYCNAGGGGERVLWCAVKATQKAYPNNICVIYTGDTDSSPEEILEKVESRFNIDLDSPRIVFFlLKYRKLVEAK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 112 LYPHFTLLGQSVGSIFLGWEALTEFVPDLYIDSMGFAFTLPVFRYLGGCQVGSYVHYPTISTDMLSVVRERNPRFNNADY 191
Cdd:cd03806 82 TYPRFTLLGQALGSMILGFEALLKLVPDVFIDTMGYPFTYPLVRLLGGCPVVAYVHYPTISTDMLNKVRSREASYNNDST 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 192 ISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILALWRTPNRTSVVYPPCDVQAFLDVPIgedneeKEQK 271
Cdd:cd03806 162 IARSSVLSIAKLLYYRLFAFLYGLAGSFADVVMVNSTWTYNHIRQLWKRNIKPSIVYPPCDTEELTKLPI------DEKT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 272 KCHSLVSVGQFRPEKDHQLQIRAFKKLLDRKEVEPagREAVKLVLIGGCRNQEDEDRVLMLRGLCQELGIADRVEFKLNI 351
Cdd:cd03806 236 RENQILSIAQFRPEKNHPLQLRAFAELLKRLPESI--RSNPKLVLIGSCRNEEDKERVEALKLLAKELILEDSVEFVVDA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 352 PFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVPYDGGPTGFLADDEDNYADAMERILSMS 431
Cdd:cd03806 314 PYEELKELLSTASIGLHTMWNEHFGIGVVEYMAAGLIPLAHASAGPLLDIVVPWDGGPTGFLASTPEEYAEAIEKILTLS 393
|
410 420
....*....|....*....|....*.
gi 529367223 432 PATRLEMRRRARLSVSRFSDQEFEGS 457
Cdd:cd03806 394 EEERLQRREAARSSAERFSDEEFERD 419
|
|
| PLN02949 |
PLN02949 |
transferase, transferring glycosyl groups |
7-467 |
0e+00 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215511 [Multi-domain] Cd Length: 463 Bit Score: 557.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 7 FSLCLCDLISWLQMKRKTRRvqdgrpAVAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEILDGAR 86
Cdd:PLN02949 15 VLLLVAIALSVLRARRSRKR------AVGFFHPYTNDGGGGERVLWCAVRAIQEENPDLDCVIYTGDHDASPDSLAARAR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 87 RRFNIRLPRPVKFVFLKHRLLVEAKLYPHFTLLGQSVGSIFLGWEALTEFVPDLYIDSMGFAFTLPVFRyLGGCQVGSYV 166
Cdd:PLN02949 89 DRFGVELLSPPKVVHLRKRKWIEEETYPRFTMIGQSLGSVYLAWEALCKFTPLYFFDTSGYAFTYPLAR-LFGCKVVCYT 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 167 HYPTISTDMLSVVRERNPRFNNADYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILALWRTPNRTSV 246
Cdd:PLN02949 168 HYPTISSDMISRVRDRSSMYNNDASIARSFWLSTCKILYYRAFAWMYGLVGRCAHLAMVNSSWTKSHIEALWRIPERIKR 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 247 VYPPCDVQAFLDVPIgEDNEEKEQkkchsLVSVGQFRPEKDHQLQIRAFKKLLDRKEVEPagrEAVKLVLIGGCRNQEDE 326
Cdd:PLN02949 248 VYPPCDTSGLQALPL-ERSEDPPY-----IISVAQFRPEKAHALQLEAFALALEKLDADV---PRPKLQFVGSCRNKEDE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 327 DRVLMLRGLCQELGIADRVEFKLNIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVPYD 406
Cdd:PLN02949 319 ERLQKLKDRAKELGLDGDVEFHKNVSYRDLVRLLGGAVAGLHSMIDEHFGISVVEYMAAGAVPIAHNSAGPKMDIVLDED 398
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 529367223 407 GGPTGFLADDEDNYADAMERILSMSPATRLEMRRRARLSVSRFSDQEFEGSFLSAMEPLMS 467
Cdd:PLN02949 399 GQQTGFLATTVEEYADAILEVLRMRETERLEIAAAARKRANRFSEQRFNEDFKDAIRPILN 459
|
|
| ALG11_N |
pfam15924 |
ALG11 mannosyltransferase N-terminus; |
31-238 |
1.00e-143 |
|
ALG11 mannosyltransferase N-terminus;
Pssm-ID: 464944 Cd Length: 209 Bit Score: 409.56 E-value: 1.00e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 31 RPAVAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEILDGARRRFNIRLPR-PVKFVFLKHRLLVE 109
Cdd:pfam15924 1 KGIVGFFHPYCNAGGGGERVLWCAVRATQRRYPNAICVVYTGDIDASKEEILAKVKSRFNIELDPsRIVFVYLRKRKLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 110 AKLYPHFTLLGQSVGSIFLGWEALTEFVPDLYIDSMGFAFTLPVFRYLGGCQVGSYVHYPTISTDMLSVVRERNPRFNNA 189
Cdd:pfam15924 81 ASTYPRFTLLGQSLGSIILAWEALSKLVPDVFIDTMGYAFTYPLVRLLGGCPVGAYVHYPTISTDMLSRVSSREAGYNND 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 529367223 190 DYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILALW 238
Cdd:pfam15924 161 SAIASSGLLSKAKLIYYRLFALLYGLVGSFADVVMVNSSWTQNHIRSLW 209
|
|
| GT4_ALG2-like |
cd03805 |
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ... |
34-458 |
1.25e-36 |
|
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.
Pssm-ID: 340834 [Multi-domain] Cd Length: 392 Bit Score: 138.88 E-value: 1.25e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 34 VAFFHPYCnaG-GGGERVLWCALRALQNRYQDVSFvvYTG--DQGVTAEEILDGarrRFNIR-----LPRpvkfvflkhr 105
Cdd:cd03805 3 VAFLHPDL--GiGGAERLVVDAALALQSRGHEVTI--YTShhDPSHCFEETKDG---TLPVRvrgdwLPR---------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 106 llveaKLYPHFTLLGQSVGSIFLGWEALTEFV--PDLYI-DSMgfAFTLPVFRYLGGCQVGSYVHYPtistDMLSVVREr 182
Cdd:cd03805 66 -----SIFGRFHALCAYLRMLYLALYLLLFSGekYDVFIvDQV--SACVPLLKLFRPSKILFYCHFP----DQLLAQRK- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 183 nprfnnadyissnpvlSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHIL----ALWRTPNRtsVVYPPCDVQAFLD 258
Cdd:cd03805 134 ----------------SLLKRLYRKPFDWLEEFTTGMADQIVVNSNFTAGVFKktfpSLAKNPPE--VLYPCVDTDSFDS 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 259 VPIGEDNEEKEQKKC-HSLVSVGQFRPEKDHQLQIRAFKKLLDRKEvepaGREAVKLVLIGGC--RNQEDEDRVLMLRGL 335
Cdd:cd03805 196 TSEDPDPGDLIAKSNkKFFLSINRFERKKNIALAIEAFAKLKQKLP----EFENVRLVIAGGYdpRVAENVEYLEELQRL 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 336 CQEL-GIADRVEFKLNIPfQELKKDLTDATIG-LHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVpydgGPTGFL 413
Cdd:cd03805 272 AEELlNVEDQVLFLRSIS-DSQKEQLLSSALAlLYTPSNEHFGIVPLEAMYAGKPVIACNSGGPLETVVE----GVTGFL 346
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 529367223 414 AD-DEDNYADAMERILSMsPATRLEMRRRARLSVS-RFSDQEFEGSF 458
Cdd:cd03805 347 CEpTPEAFAEAMLKLAND-PDLADRMGAAGRKRVKeKFSREAFAERL 392
|
|
| Glycos_transf_1 |
pfam00534 |
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ... |
276-443 |
2.13e-27 |
|
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
Pssm-ID: 425737 [Multi-domain] Cd Length: 158 Bit Score: 107.36 E-value: 2.13e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 276 LVSVGQFRPEKDHQLQIRAFKKLLDRKEVepagreaVKLVLIGgcrNQEDEDRvlmLRGLCQELGIADRVEFKLNIPFQE 355
Cdd:pfam00534 5 ILFVGRLEPEKGLDLLIKAFALLKEKNPN-------LKLVIAG---DGEEEKR---LKKLAEKLGLGDNVIFLGFVSDED 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 356 LKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVPYDggpTGFLAD--DEDNYADAMERILSmSPA 433
Cdd:pfam00534 72 LPELLKIADVFVLPSRYEGFGIVLLEAMACGLPVIASDVGGPP-EVVKDGE---TGFLVKpnNAEALAEAIDKLLE-DEE 146
|
170
....*....|
gi 529367223 434 TRLEMRRRAR 443
Cdd:pfam00534 147 LRERLGENAR 156
|
|
| GT4_PimA-like |
cd03801 |
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
34-450 |
9.34e-24 |
|
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 102.23 E-value: 9.34e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 34 VAFFHPYCNAG-GGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEIldgarRRFNIRLPRPVKFVFLKHRLLVEAKL 112
Cdd:cd03801 2 ILLLSPELPPPvGGAERHVRELARALAARGHDVTVLTPADPGEPPEELE-----DGVIVPLLPSLAALLRARRLLRELRP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 113 YPHFtllgqsvgsiflgwealteFVPDL-YIDSMGFAFTLPVFRYLGGCQVGSYVHYPTistdmlsvvrernPRFNNADY 191
Cdd:cd03801 77 LLRL-------------------RKFDVvHAHGLLAALLAALLALLLGAPLVVTLHGAE-------------PGRLLLLL 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 192 ISSNPVLSAIKVIYYCVfallyglagscsDVIMVNSTWTLGHILAL-WRTPNRTSVVYPPCDVQAFlDVPIGEDNEEKEQ 270
Cdd:cd03801 125 AAERRLLARAEALLRRA------------DAVIAVSEALRDELRALgGIPPEKIVVIPNGVDLERF-SPPLRRKLGIPPD 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 271 KKchSLVSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIGgcRNQEDEDRVLMLrglcqELGIADRVEFKLN 350
Cdd:cd03801 192 RP--VLLFVGRLSPRKGVDLLLEALAKLLRR-------GPDVRLVIVG--GDGPLRAELEEL-----ELGLGDRVRFLGF 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 351 IPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVPydgGPTGFLA--DDEDNYADAMERIL 428
Cdd:cd03801 256 VPDEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLP-EVVED---GEGGLVVppDDVEALADALLRLL 331
|
410 420
....*....|....*....|...
gi 529367223 429 SmSPATRLEMRRRARLSVS-RFS 450
Cdd:cd03801 332 A-DPELRARLGRAARERVAeRFS 353
|
|
| GT4_GT28_WabH-like |
cd03811 |
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ... |
34-455 |
1.60e-22 |
|
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.
Pssm-ID: 340839 [Multi-domain] Cd Length: 351 Bit Score: 98.58 E-value: 1.60e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 34 VAFFHPyCNAGGGGERVLWCALRALQNRYQDVSFVVYTGdqgvtaEEILDGARRRFNIRLPRPVKFVFLKHRLLVEAKLY 113
Cdd:cd03811 2 ILFVIP-SLSGGGAERVLLNLANALDKRGYDVTLVLLRD------EGDLDKQLNGDVKLIRLLIRVLKLIKLGLLKAILK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 114 phftllgqsVGSIFLgwealtEFVPDLYIDSMGFAFTLPVFRYLGGCQVgsyvhyptistdmlsVVRERNPRFNNadYIS 193
Cdd:cd03811 75 ---------LKRILK------RAKPDVVISFLGFATYIVAKLAAARSKV---------------IAWIHSSLSKL--YYL 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 194 SNPVLSAIKVIYYCvfallyglagscsDVIMVNSTWTLGHILAL-WRTPNRTSVVYPPCDVQAFLDVPIGEDNEEKEQKK 272
Cdd:cd03811 123 KKKLLLKLKLYKKA-------------DKIVCVSKGIKEDLIRLgPSPPEKIEVIYNPIDIDRIRALAKEPILNEPEDGP 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 273 chSLVSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIGgcrNQEDEDRvlmLRGLCQELGIADRVEF---KL 349
Cdd:cd03811 190 --VILAVGRLDPQKGHDLLIEAFAKLRKK-------YPDVKLVILG---DGPLREE---LEKLAKELGLAERVIFlgfQS 254
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 350 NiPFQELKKdltdATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVvpyDGGPTGFLADDEDNYADAMERILS 429
Cdd:cd03811 255 N-PYPYLKK----ADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPGPR-EIL---DDGENGLLVPDGDAAALAGILAAL 325
|
410 420
....*....|....*....|....*.
gi 529367223 430 MSPATRLEMRRRARLSVSRFSDQEFE 455
Cdd:cd03811 326 LQKKLDAALRERLAKAQEAVFREYTI 351
|
|
| GT4_sucrose_synthase |
cd03800 |
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ... |
215-449 |
2.20e-19 |
|
sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.
Pssm-ID: 340830 [Multi-domain] Cd Length: 398 Bit Score: 89.61 E-value: 2.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 215 LAGSCSDVIMVNSTWTLGHILALWRT-PNRTSVVYPPCDVQAFldVPIGEDNEE-----KEQKKcHSLVSVGQFRPEKDH 288
Cdd:cd03800 159 QILEAADRVIASTPQEADELISLYGAdPSRINVVPPGVDLERF--FPVDRAEARrarllLPPDK-PVVLALGRLDPRKGI 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 289 QLQIRAFKKLLDRkevepagREAVKLVLIGGCRNQEDEDRVLMLRGLCQELGIADRVEFKLNIPFQELKKDLTDATIGLH 368
Cdd:cd03800 236 DTLVRAFAQLPEL-------RELANLVLVGGPSDDPLSMDREELAELAEELGLIDRVRFPGRVSRDDLPELYRAADVFVV 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 369 TMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVPydgGPTGFLAD--DEDNYADAMERILsMSPATRLEMRRRARLSV 446
Cdd:cd03800 309 PSLYEPFGLTAIEAMACGTPVVATAVGGLQ-DIVRD---GRTGLLVDphDPEALAAALRRLL-DDPALWQRLSRAGLERA 383
|
...
gi 529367223 447 SRF 449
Cdd:cd03800 384 RAH 386
|
|
| GT4_WlbH-like |
cd03798 |
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ... |
277-454 |
4.72e-18 |
|
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
Pssm-ID: 340828 [Multi-domain] Cd Length: 376 Bit Score: 85.51 E-value: 4.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 277 VSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIGgcrNQEDEDRvlmLRGLCQELGIADRVEFKLNIPFQEL 356
Cdd:cd03798 204 LFVGRLIPRKGIDLLLEAFARLAKA-------RPDVVLLIVG---DGPLREA---LRALAEDLGLGDRVTFTGRLPHEQV 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 357 KKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVvpyDGGPTGFLAD--DEDNYADAMERILsMSPAT 434
Cdd:cd03798 271 PAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVGGIP-EVV---GDPETGLLVPpgDADALAAALRRAL-AEPYL 345
|
170 180
....*....|....*....|
gi 529367223 435 RLEMRRRARLSVSRFSDQEF 454
Cdd:cd03798 346 RELGEAARARVAERFSWVKA 365
|
|
| GT4_MtfB-like |
cd03809 |
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ... |
219-450 |
1.94e-16 |
|
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Pssm-ID: 340838 [Multi-domain] Cd Length: 362 Bit Score: 80.49 E-value: 1.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 219 CSDVIMVNSTWTLGHILALWRTP-NRTSVVYPPCDVQAFLDVPIGEDNEEKEQKkCHSLVSVGQFRPEKDHQLQIRAFKK 297
Cdd:cd03809 138 RADAIITVSEATRDDIIKFYGVPpEKIVVIPLGVDPSFFPPESAAVLIAKYLLP-EPYFLYVGTLEPRKNHERLLKAFAL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 298 LLDRKEVepagreaVKLVLIGGcrnqeDEDRVLMLRGLCQELGIADRVEFKLNIPFQELKKDLTDATI----GLHtmwnE 373
Cdd:cd03809 217 LKKQGGD-------LKLVIVGG-----KGWEDEELLDLVKKLGLGGRVRFLGYVSDEDLPALYRGARAfvfpSLY----E 280
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 529367223 374 HFGIGIVECMAAGTIILAhkSGGPKLDIVVpydgGPTGFLAD--DEDNYADAMERILSmSPATRLEMRRRARLSVSRFS 450
Cdd:cd03809 281 GFGLPVLEAMACGTPVIA--SNISVLPEVA----GDAALYFDplDPESIADAILRLLE-DPSLREELIRKGLERAKKFS 352
|
|
| GT4_UGDG-like |
cd03817 |
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ... |
246-450 |
1.84e-14 |
|
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Pssm-ID: 340844 [Multi-domain] Cd Length: 372 Bit Score: 74.62 E-value: 1.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 246 VVYPPCDVQAFLDVPIGEDNEE---KEQKKchSLVSVGQFRPEKDHQLQIRAFKKLLDRKEvepagreaVKLVLIG-GCR 321
Cdd:cd03817 173 VIPNGIDLDKFEKPLNTEERRKlglPPDEP--ILLYVGRLAKEKNIDFLLRAFAELKKEPN--------IKLVIVGdGPE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 322 NQEdedrvlmLRGLCQELGIADRVEFKLNIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDI 401
Cdd:cd03817 243 REE-------LKELARELGLADKVIFTGFVPREELPEYYKAADLFVFASTTETQGLVYLEAMAAGLPVVAAKDPAAS-EL 314
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 529367223 402 VvpyDGGPTGFL-ADDEDNYADAMERILSMsPATRLEMRRRARLSVSRFS 450
Cdd:cd03817 315 V---EDGENGFLfEPNDETLAEKLLHLREN-LELLRKLSKNAEISAREFA 360
|
|
| GT4_WbnK-like |
cd03807 |
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ... |
276-450 |
1.26e-13 |
|
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.
Pssm-ID: 340836 [Multi-domain] Cd Length: 362 Bit Score: 71.96 E-value: 1.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 276 LVSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIG-GCRNQEDEdrvLMLRglcqELGIADRVEFKLNIpfQ 354
Cdd:cd03807 193 IGIVGRLHPVKDHSDLLRAAALLVET-------HPDLRLLLVGrGPERPNLE---RLLL----ELGLEDRVHLLGER--S 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 355 ELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGpKLDIVVPydggPTGFL--ADDEDNYADAMERILSMsP 432
Cdd:cd03807 257 DVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVGG-AAELVDD----GTGFLvpAGDPQALADAIRALLED-P 330
|
170
....*....|....*....
gi 529367223 433 ATRLEMRRRARLSV-SRFS 450
Cdd:cd03807 331 EKRARLGRAARERIaNEFS 349
|
|
| Glycosyltransferase_GTB-type |
cd01635 |
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
221-408 |
6.57e-13 |
|
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340816 [Multi-domain] Cd Length: 235 Bit Score: 68.20 E-value: 6.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 221 DVIMVNSTW--TLGHILALWRTPNRTSVVYPPCDVQAFLDVPIGEDNEEKEQKKCHSLVSVGQFRPEKDHQLQIRAFKKL 298
Cdd:cd01635 56 DVVHAHSPHaaALAALLAARLLGIPIVVTVHGPDSLESTRSELLALARLLVSLPLADKVSVGRLVPEKGIDLLLEALALL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 299 ldrkevePAGREAVKLVLIGGCRNQEDEDRVLmlrglcQELGIADRVEFKLNIPFQELKKDLT-DATIGLHTMWNEHFGI 377
Cdd:cd01635 136 -------KARLPDLVLVLVGGGGEREEEEALA------AALGLLERVVIIGGLVDDEVLELLLaAADVFVLPSRSEGFGL 202
|
170 180 190
....*....|....*....|....*....|.
gi 529367223 378 GIVECMAAGTIILAHKSGGPKLDIVVPYDGG 408
Cdd:cd01635 203 VLLEAMAAGKPVIATDVGGIPEFVVDGENGL 233
|
|
| GT4_AviGT4-like |
cd03802 |
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ... |
236-452 |
2.95e-12 |
|
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.
Pssm-ID: 340832 [Multi-domain] Cd Length: 333 Bit Score: 67.70 E-value: 2.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 236 ALWRTPNRTSVVYPPCDVQAFLDVPIGEDNeekeqkkchsLVSVGQFRPEKDHQLQIRAFKKlldrkevepAGReavKLV 315
Cdd:cd03802 142 AATPPIDYLTVVHNGLDPADYRFQPDPEDY----------LAFLGRIAPEKGLEDAIRVARR---------AGL---PLK 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 316 LIGGCRNQEDEDRVlmlrglcQELGIADRVEFKLNIPFQELKKDLTDATIGLHT-MWNEHFGIGIVECMAAGTIILAHKS 394
Cdd:cd03802 200 IAGKVRDEDYFYYL-------QEPLPGPRIEFIGEVGHDEKQELLGGARALLFPiNWDEPFGLVMIEAMACGTPVIAYRR 272
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 395 GGPkLDIVVPydgGPTGFLADDEDNYADAMERILSMSPATrleMRRRA--RLSVSRFSDQ 452
Cdd:cd03802 273 GGL-PEVIQH---GETGFLVDSVEEMAEAIANIDRIDRAA---CRRYAedRFSAARMADR 325
|
|
| GT4_AmsD-like |
cd03820 |
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ... |
34-450 |
1.32e-11 |
|
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.
Pssm-ID: 340847 [Multi-domain] Cd Length: 351 Bit Score: 65.72 E-value: 1.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 34 VAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEildgarrrfnirLPRPVKFVFLKHRLLVEAKLY 113
Cdd:cd03820 2 IAIVIPSISNAGGAERVAINLANHLAKKGYDVTIISLDSAEKPPFYE------------LDDNIKIKNLGDRKYSHFKLL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 114 PHFtllgQSVGSIFLgwEALTEFVPDLYIDSMGFAFTLPvfrylggcqvgsyvhyPTISTDMLSVVRERNPRFNNADYIS 193
Cdd:cd03820 70 LKY----FKKVRRLR--KYLKNNKPDVVISFRTSLLTFL----------------ALIGLKSKLIVWEHNNYEAYNKGLR 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 194 SnpvlsaikviyYCVFALLYGLAgscsDVIMVNSTWTLghILALWRTPNRTSVVYPPCDvqaFLDVPIGEDNEEKeqkkc 273
Cdd:cd03820 128 R-----------LLLRRLLYKRA----DKIVVLTEADK--LKKYKQPNSNVVVIPNPLS---FPSEEPSTNLKSK----- 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 274 hSLVSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIGGCrnqEDEDRvlmLRGLCQELGIADRVEFKLNIpf 353
Cdd:cd03820 183 -RILAVGRLTYQKGFDLLIEAWALIAKK-------HPDWKLRIYGDG---PEREE---LEKLIDKLGLEDRVKLLGPT-- 246
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 354 QELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKS-GGPKlDIVvpyDGGPTGFLADDED--NYADAMERILSm 430
Cdd:cd03820 247 KNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCpTGPS-EII---EDGENGLLVPNGDvdALAEALLRLME- 321
|
410 420
....*....|....*....|
gi 529367223 431 SPATRLEMRRRARLSVSRFS 450
Cdd:cd03820 322 DEELRKKMGKNARKNAERFS 341
|
|
| GT4_WbaZ-like |
cd03804 |
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ... |
221-458 |
1.33e-11 |
|
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.
Pssm-ID: 340833 [Multi-domain] Cd Length: 356 Bit Score: 65.77 E-value: 1.33e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 221 DVIMVNSTWTLGHIlalWRTPNRTS-VVYPPCDVQAFLDVPIGEDneekeqkkchSLVSVGQFRPEKDHQLQIRAFKKLl 299
Cdd:cd03804 159 DLFIANSQFVARRI---KKFYGREStVIYPPVDTDAFAPAADKED----------YYLTASRLVPYKRIDLAVEAFNEL- 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 300 drkevepaGReavKLVLIGgcrNQEDEDRvlmLRGlcqelgIADR-VEFKLNIPFQELKKDLTDATiGLHTMWNEHFGIG 378
Cdd:cd03804 225 --------PK---RLVVIG---DGPDLDR---LRA------MASPnVEFLGYQPDEVLKELLSKAR-AFVFAAEEDFGIV 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 379 IVECMAAGTIILAHKSGGpKLDIVVPydgGPTGFLADDEDNYA--DAMERILSMSPATRLEmrrRARLSVSRFSDQEFEG 456
Cdd:cd03804 281 PVEAQACGTPVIAFGKGG-ALETVRP---GPTGILFGEQTVESlkAAVEEFEQNFDRFKPQ---AIRANAERFSRARFRQ 353
|
..
gi 529367223 457 SF 458
Cdd:cd03804 354 EI 355
|
|
| RfaB |
COG0438 |
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
360-467 |
5.88e-11 |
|
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 59.62 E-value: 5.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 360 LTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVPydgGPTGFLAD--DEDNYADAMERILSmSPATRLE 437
Cdd:COG0438 18 LAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLP-EVIED---GETGLLVPpgDPEALAEAILRLLE-DPELRRR 92
|
90 100 110
....*....|....*....|....*....|.
gi 529367223 438 MRRRAR-LSVSRFSDQEFEGSFLSAMEPLMS 467
Cdd:COG0438 93 LGEAAReRAEERFSWEAIAERLLALYEELLA 123
|
|
| Glyco_trans_1_4 |
pfam13692 |
Glycosyl transferases group 1; |
276-429 |
1.41e-10 |
|
Glycosyl transferases group 1;
Pssm-ID: 463957 [Multi-domain] Cd Length: 138 Bit Score: 59.06 E-value: 1.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 276 LVSVGQFRPE-KDHQLQIRAFKKLLDRkevepagREAVKLVLIGGCRNQEDEDRVLmlrglcqelGIADRVEFklnIPF- 353
Cdd:pfam13692 4 ILFVGRLHPNvKGVDYLLEAVPLLRKR-------DNDVRLVIVGDGPEEELEELAA---------GLEDRVIF---TGFv 64
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 529367223 354 QELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVpydgGPTGFLA--DDEDNYADAMERILS 429
Cdd:pfam13692 65 EDLAELLAAADVFVLPSLYEGFGLKLLEAMAAGLPVVATDVGGIP-ELVD----GENGLLVppGDPEALAEAILRLLE 137
|
|
| GT4_CapM-like |
cd03808 |
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ... |
208-453 |
3.18e-10 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.
Pssm-ID: 340837 [Multi-domain] Cd Length: 358 Bit Score: 61.46 E-value: 3.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 208 VFALLYGLAGSCSDVIMVNSTWTLGHILALWRTPNRTSVVYPPCDVQAFLDVPIGEDNEEKEqkkcHSLVSVGQFRPEKD 287
Cdd:cd03808 128 LYLLLEKLALLFTDKVIFVNEDDRDLAIKKGIIKKKKTVLIPGSGVDLDRFQYSPESLPSEK----VVFLFVARLLKDKG 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 288 HQLQIRAFKKLLDRKevepagrEAVKLVLIGGCRnqEDEDRVLMLrglcQELGIADRVEF---KLNIPfqelkKDLTDAT 364
Cdd:cd03808 204 IDELIEAAKILKKKG-------PNVRFLLVGDGE--LENPSEILI----EKLGLEGRIEFlgfRSDVP-----ELLAESD 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 365 IGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVPydgGPTGFLAD--DEDNYADAMERILSmSPATRLEMRRRA 442
Cdd:cd03808 266 VFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCR-ELVID---GVNGFLVPpgDVEALADAIEKLIE-DPELRKEMGEAA 340
|
250
....*....|..
gi 529367223 443 RLSV-SRFSDQE 453
Cdd:cd03808 341 RKRVeEKFDEEK 352
|
|
| GT4_BshA-like |
cd04962 |
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ... |
263-450 |
1.32e-09 |
|
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340859 [Multi-domain] Cd Length: 370 Bit Score: 59.67 E-value: 1.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 263 EDNEEKEQKKCHS----LVSVGQFRPEKDHQLQIRAFKKLldRKEVePAgreavKLVLIGgcrnqEDEDRVLMLRgLCQE 338
Cdd:cd04962 182 PAGALKRRLLAPPdekvVIHVSNFRPVKRIDDVVRVFARV--RRKI-PA-----KLLLVG-----DGPERVPAEE-LARE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 339 LGIADRVEFKLNIPfqELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGpkLDIVVpyDGGPTGFLAD--D 416
Cdd:cd04962 248 LGVEDRVLFLGKQD--DVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGG--IPEVV--KHGETGFLSDvgD 321
|
170 180 190
....*....|....*....|....*....|....*
gi 529367223 417 EDNYADAMERILSmSPATRLEMRRRARL-SVSRFS 450
Cdd:cd04962 322 VDAMAKSALSILE-DDELYNRMGRAARKrAAERFD 355
|
|
| GT4-like |
cd03814 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
276-463 |
7.13e-09 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340842 [Multi-domain] Cd Length: 365 Bit Score: 57.30 E-value: 7.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 276 LVSVGQFRPEKDhqlqIRAFKKLLDRkevePAGREAVKLVLIGGCRNQEdedrVLMLRGLCQE-LGIADRvefklnipfQ 354
Cdd:cd03814 201 LLYVGRLAPEKN----LEALLDADLP----LAASPPVRLVVVGDGPARA----ELEARGPDVIfTGFLTG---------E 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 355 ELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVvpyDGGPTGFLAD--DEDNYADAMERiLSMSP 432
Cdd:cd03814 260 ELARAYASADVFVFPSRTETFGLVVLEAMASGLPVVAADAGGPR-DIV---RPGGTGALVEpgDAAAFAAALRA-LLEDP 334
|
170 180 190
....*....|....*....|....*....|.
gi 529367223 433 ATRLEMRRRARLSVSRFSDQEFEGSFLSAME 463
Cdd:cd03814 335 ELRRRMAARARAEAERYSWEAFLDNLLDYYA 365
|
|
| GT4_WavL-like |
cd03819 |
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ... |
279-444 |
3.53e-08 |
|
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.
Pssm-ID: 340846 [Multi-domain] Cd Length: 345 Bit Score: 55.05 E-value: 3.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 279 VGQFRPEKDHQLQIRAFKKLLDRKEVepagreavkLVLIGGCRNQEDEDRVLMlrglcQELGIADRVEFKLNIPfqELKK 358
Cdd:cd03819 188 VGRLSPEKGWLLLVDAAAELKDEPDF---------RLLVAGDGPERDEIRRLV-----ERLGLRDRVTFTGFRE--DVPA 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 359 DLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPkLDIVVPydgGPTGFLADDEDN--YADAMERiLSMSPATRL 436
Cdd:cd03819 252 ALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGA-REIVVH---GRTGLLVPPGDAeaLADAIRA-AKLLPEARE 326
|
....*...
gi 529367223 437 EMRRRARL 444
Cdd:cd03819 327 KLQAAAAL 334
|
|
| GT4_WbuB-like |
cd03794 |
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ... |
241-450 |
1.28e-07 |
|
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
Pssm-ID: 340825 [Multi-domain] Cd Length: 391 Bit Score: 53.50 E-value: 1.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 241 PNRTSVVYPPCDVQAFLDVPIGEDNEEKEQKKCHSLVSVGQFRPEKDHQLQIRAFKKLLDRKEVepagreavKLVLIGGC 320
Cdd:cd03794 185 KEKIIVIPNWADLEEFKPPPKDELRKKLGLDDKFVVVYAGNIGKAQGLETLLEAAERLKRRPDI--------RFLFVGDG 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 321 RNQEDEDRVLMLRGLcqelgiaDRVEFKLNIPFQELKKDLTDATIGLHTMWNEHFGIGIV-----ECMAAGTIILAHKSG 395
Cdd:cd03794 257 DEKERLKELAKARGL-------DNVTFLGRVPKEEVPELLSAADVGLVPLKDNPANRGSSpsklfEYMAAGKPILASDDG 329
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 529367223 396 GPKLDIVVpydgGPTGFLADDEDN--YADAMERiLSMSPATRLEMRRRAR-LSVSRFS 450
Cdd:cd03794 330 GSDLAVEI----NGCGLVVEPGDPeaLADAILE-LLDDPELRRAMGENGReLAEEKFS 382
|
|
| GT4-like |
cd03813 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
190-453 |
3.83e-07 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340841 [Multi-domain] Cd Length: 474 Bit Score: 52.34 E-value: 3.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 190 DYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILALWRTPNRTSVVYPPCDVQAFLDVPigednEEKE 269
Cdd:cd03813 215 EILQSTWIMGYIKKLWIRFFERLGKLAYQQADKIISLYEGNRRRQIRLGADPDKTRVIPNGIDIQRFAPAR-----EERP 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 270 QKKCHSLVSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIGGcrNQEDEDRVLMLRGLCQELGIADRVEFkl 349
Cdd:cd03813 290 EKEPPVVGLVGRVVPIKDVKTFIRAFKLVRRA-------MPDAEGWLIGP--EDEDPEYAQECKRLVASLGLENKVKF-- 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 350 nIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVvpYDG----GPTGFL---ADDEDnYAD 422
Cdd:cd03813 359 -LGFQNIKEYYPKLGLLVLTSISEGQPLVILEAMASGVPVVATDVGSCR-ELI--YGAddalGQAGLVvppADPEA-LAE 433
|
250 260 270
....*....|....*....|....*....|.
gi 529367223 423 AMERILSmSPATRLEMRRRARLSVSRFSDQE 453
Cdd:cd03813 434 ALIKLLR-DPELRQAFGEAGRKRVEKYYTLE 463
|
|
| GT4_trehalose_phosphorylase |
cd03792 |
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ... |
248-448 |
1.77e-06 |
|
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.
Pssm-ID: 340823 [Multi-domain] Cd Length: 378 Bit Score: 50.01 E-value: 1.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 248 YPPCDVQAFLDVPIGEDNEEKeqkkchSLVSVGQFRPEKDHQLQIRAFKKLLDRKEVepagreaVKLVLIGGcRNQEDED 327
Cdd:cd03792 178 LSPADIRYYLEKPFVIDPERP------YILQVARFDPSKDPLGVIDAYKLFKRRAEE-------PQLVICGH-GAVDDPE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 328 RVLMLRGLCQELGIADRVEF-KLNIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVvpyd 406
Cdd:cd03792 244 GSVVYEEVMEYAGDDHDIHVlRLPPSDQEINALQRAATVVLQLSTREGFGLTVSEALWKGKPVIATPAGGIPLQVI---- 319
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 529367223 407 GGPTGFLADDEDNYADAMERILSmSPATRLEMRRRARLSVSR 448
Cdd:cd03792 320 DGETGFLVNSVEGAAVRILRLLT-DPELRRKMGLAAREHVRD 360
|
|
| GT4_GtfA-like |
cd04949 |
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ... |
268-451 |
5.52e-06 |
|
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340855 [Multi-domain] Cd Length: 328 Bit Score: 48.07 E-value: 5.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 268 KEQKKcHSLVSVGQFRPEKDHQLQIRAFKKLldRKEVePagreAVKLVLIGgcRNQEDEDrvlmLRGLCQELGIADRVEF 347
Cdd:cd04949 156 HERKS-NKIITISRLAPEKQLDHLIEAVAKA--VKKV-P----EITLDIYG--YGEEREK----LKKLIEELHLEDNVFL 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 348 K--LNIPFQELKkdltDATIGLHTMWNEHFGIGIVECMAAGTIILAHKsggpkldivVPYdgGPTGFLADDE-------- 417
Cdd:cd04949 222 KgyHSNLDQEYQ----DAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYD---------VKY--GPSELIEDGEngyliekn 286
|
170 180 190
....*....|....*....|....*....|....*.
gi 529367223 418 --DNYADAMERILSmSPATRLEMRRRARLSVSRFSD 451
Cdd:cd04949 287 niDALADKIIELLN-DPEKLQQFSEESYKIAEKYST 321
|
|
| GT4_ExpE7-like |
cd03823 |
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ... |
279-452 |
8.91e-06 |
|
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).
Pssm-ID: 340850 [Multi-domain] Cd Length: 357 Bit Score: 47.71 E-value: 8.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 279 VGQFRPEKDHQLQIRAFKKLlDRKEVEpagreavkLVLIGGCRNQEdedrvlmlrglCQELGIADRVEFKLNIPFQELKK 358
Cdd:cd03823 197 IGRLTEEKGIDLLVEAFKRL-PREDIE--------LVIAGHGPLSD-----------ERQIEGGRRIAFLGRVPTDDIKD 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 359 --DLTDATIgLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVvpydGGPTGFL--ADDEDNYADAMERI-----LS 429
Cdd:cd03823 257 fyEKIDVLV-VPSIWPEPFGLVVREAIAAGLPVIASDLGGIAELIQ----PGVNGLLfaPGDAEDLAAAMRRLltdpaLL 331
|
170 180
....*....|....*....|...
gi 529367223 430 MSPATRLEMRRRARLSVSRFSDQ 452
Cdd:cd03823 332 ERLRAGAEPPRSTESQAEEYLKL 354
|
|
| PLN02871 |
PLN02871 |
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase |
373-450 |
1.81e-05 |
|
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
Pssm-ID: 215469 [Multi-domain] Cd Length: 465 Bit Score: 47.01 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 373 EHFGIGIVECMAAGTIILAHKSGGPKlDIVVPYDGGPTGFLADDEDnYADAMERI--LSMSPATRLEMRRRARLSVSRFS 450
Cdd:PLN02871 342 ETLGFVVLEAMASGVPVVAARAGGIP-DIIPPDQEGKTGFLYTPGD-VDDCVEKLetLLADPELRERMGAAAREEVEKWD 419
|
|
| GT4_WbdM_like |
cd04951 |
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ... |
256-450 |
4.67e-05 |
|
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340857 [Multi-domain] Cd Length: 360 Bit Score: 45.51 E-value: 4.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 256 FLDVPIGEDNEEKEQKKCHSL---------VSVGQFRPEKDHQLQIRAFKKLLDRKEvepagreAVKLVLIGgcrnqEDE 326
Cdd:cd04951 162 GIDLNKFKKDINVRLKIRNKLnlkndefviLNVGRLTEAKDYPNLLLAISELILSKN-------DFKLLIAG-----DGP 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 327 DRVLMLRGLCQeLGIADRVEFklnIPFQELKKDLTDAT--IGLHTMWnEHFGIGIVECMAAGTIILAHKSGGPKlDIVVP 404
Cdd:cd04951 230 LRNELERLICN-LNLVDRVIL---LGQISNISEYYNAAdlFVLSSEW-EGFGLVVAEAMACERPVVATDAGGVA-EVVGD 303
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 529367223 405 YDggptgFLADDEDNY--ADAMERILSMSPATRLEMRRRARLSVSRFS 450
Cdd:cd04951 304 HN-----YVVPVSDPQllAEKIKEIFDMSDEERDILGNKNEYIAKNFS 346
|
|
| GT4_Bme6-like |
cd03821 |
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ... |
276-450 |
6.43e-05 |
|
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.
Pssm-ID: 340848 [Multi-domain] Cd Length: 377 Bit Score: 45.05 E-value: 6.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 276 LVSVGQFRPEKDHQLQIRAFKKLLDrkevepAGREaVKLVLIGgcrnqEDEDRVLMLRGLCQELGIADRVEFKLNIPFQE 355
Cdd:cd03821 207 ILFLGRIHPKKGLDLLIRAARKLAE------QGRD-WHLVIAG-----PDDGAYPAFLQLQSSLGLGDRVTFTGPLYGEA 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 356 LKKDLTDATIGLHTMWNEHFGIGIVECMAAGT-IILAHKSGGPKLdivvpYDGGpTGFLADDEDNY-ADAMERILS--MS 431
Cdd:cd03821 275 KWALYASADLFVLPSYSENFGNVVAEALACGLpVVITDKCGLSEL-----VEAG-CGVVVDPNVSSlAEALAEALRdpAD 348
|
170
....*....|....*....
gi 529367223 432 PATRLEMRRRARLSVSRFS 450
Cdd:cd03821 349 RKRLGEMARRARQVEENFS 367
|
|
| GT4_WcaC-like |
cd03825 |
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ... |
346-452 |
2.60e-04 |
|
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
Pssm-ID: 340851 [Multi-domain] Cd Length: 364 Bit Score: 43.09 E-value: 2.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529367223 346 EFKLNIPFQELKKDLTDATIGLHTMWN-----------EHFGIGIVECMAAGTIILAHKSGGPkLDIVvpyDGGPTGFLA 414
Cdd:cd03825 236 PQIVILPFDIISLGYIDDDEQLVDIYSaadlfvhpslaDNLPNTLLEAMACGTPVVAFDTGGS-PEIV---QHGVTGYLV 311
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 529367223 415 DDED--NYADAMERILsMSPATRLEMRRRAR-LSVSRFSDQ 452
Cdd:cd03825 312 PPGDvqALAEAIEWLL-ANPKERESLGERARaLAENHFDQR 351
|
|
| GT5_Glycogen_synthase_DULL1-like |
cd03791 |
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ... |
373-442 |
6.69e-03 |
|
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.
Pssm-ID: 340822 [Multi-domain] Cd Length: 474 Bit Score: 38.70 E-value: 6.69e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 529367223 373 EHFGIGIVECMAAGTIILAHKSGGPKlDIVVPYD---GGPTGFLADDEDNYA--DAMERILSM--SPATRLEMRRRA 442
Cdd:cd03791 379 EPCGLVQMYAMRYGTLPIVRRTGGLA-DTVFDYDpetGEGTGFVFEDYDAEAllAALRRALALyrNPELWRKLQKNA 454
|
|
| |
