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Conserved domains on  [gi|520975469|ref|NP_001265566|]
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fms-related tyrosine kinase 3 ligand isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Flt3_lig super family cl03795
flt3 ligand; The flt3 ligand is a short chain cytokine with a 4 helical bundle fold.
 1-77 1.73e-46

flt3 ligand; The flt3 ligand is a short chain cytokine with a 4 helical bundle fold.


The actual alignment was detected with superfamily member pfam02947:

Pssm-ID: 460760  Cd Length: 131  Bit Score: 147.62  E-value: 1.73e-46
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 520975469    1 MERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQ 77
Cdd:pfam02947  55 MERLKTVAGSKLQELLEKVNTEIHFVTSCDFQPLPSCLRFVQTNISHLLQDTSAQLLALKPKITRRNFSRCLELRCQ 131
 
Name Accession Description Interval E-value
Flt3_lig pfam02947
flt3 ligand; The flt3 ligand is a short chain cytokine with a 4 helical bundle fold.
 1-77 1.73e-46

flt3 ligand; The flt3 ligand is a short chain cytokine with a 4 helical bundle fold.


Pssm-ID: 460760  Cd Length: 131  Bit Score: 147.62  E-value: 1.73e-46
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 520975469    1 MERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQ 77
Cdd:pfam02947  55 MERLKTVAGSKLQELLEKVNTEIHFVTSCDFQPLPSCLRFVQTNISHLLQDTSAQLLALKPKITRRNFSRCLELRCQ 131
 
Name Accession Description Interval E-value
Flt3_lig pfam02947
flt3 ligand; The flt3 ligand is a short chain cytokine with a 4 helical bundle fold.
 1-77 1.73e-46

flt3 ligand; The flt3 ligand is a short chain cytokine with a 4 helical bundle fold.


Pssm-ID: 460760  Cd Length: 131  Bit Score: 147.62  E-value: 1.73e-46
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 520975469    1 MERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQ 77
Cdd:pfam02947  55 MERLKTVAGSKLQELLEKVNTEIHFVTSCDFQPLPSCLRFVQTNISHLLQDTSAQLLALKPKITRRNFSRCLELRCQ 131
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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