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Conserved domains on  [gi|442621415|ref|NP_001263013|]
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distracted, isoform C [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
343-614 3.88e-22

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 97.92  E-value: 3.88e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  343 WETVHPedgseVPDKRYGASTVMYGDKIFMYGGVVKGhGISNELWAFDVSARTWaniSVRADPscnatggttamcgPLHV 422
Cdd:COG3055     3 WSSLPD-----LPTPRSEAAAALLDGKVYVAGGLSGG-SASNSFEVYDPATNTW---SELAPL-------------PGPP 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  423 VGHTATLVpgYGDKnnyqymVVIFG----HSPNYGYLNTVQEFNFASREWRIVPTTGyvvKGGYGHSAAydFLTEKVYVY 498
Cdd:COG3055    61 RHHAAAVA--QDGK------LYVFGgftgANPSSTPLNDVYVYDPATNTWTKLAPMP---TPRGGATAL--LLDGKIYVV 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  499 GGIVSESESSQVlssrlYAYEPATRVWSLLSAAPSARLLHTANFVNQGLMMVFGGNTHNDTSQSY--------------- 563
Cdd:COG3055   128 GGWDDGGNVAWV-----EVYDPATGTWTQLAPLPTPRDHLAAAVLPDGKILVIGGRNGSGFSNTWttlaplptaraghaa 202

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442621415  564 -----------GAKCYSQDLLVYDVYCDSWHYHP-MPghlqadLARFGHSSVVFEESLYIYGG 614
Cdd:COG3055   203 avlggkilvfgGESGFSDEVEAYDPATNTWTALGeLP------TPRHGHAAVLTDGKVYVIGG 259
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 86-212 7.36e-14

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 68.98  E-value: 7.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415   86 CGGKVRmYHPMGTIH-DGW-GNYSVSVKCSWLIDARHPHwnrrhntnpsrtaNIRIHLREFATE----CGWDHLYIYDGD 159
Cdd:cd00041     1 CGGTLT-ASTSGTISsPNYpNNYPNNLNCVWTIEAPPGY-------------RIRLTFEDFDLEsspnCSYDYLEIYDGP 66

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 442621415  160 SVDSPLLAVFSGLmyrgnfsiRRVPQVIATSGTALVHFFSDDAYNMSGFNLTY 212
Cdd:cd00041    67 STSSPLLGRFCGS--------TLPPPIISSGNSLTVRFRSDSSVTGRGFKATY 111
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 948-994 1.03e-06

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


:

Pssm-ID: 238012  Cd Length: 50  Bit Score: 46.58  E-value: 1.03e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442621415  948 RCNCNGHS----YCNDQQ-HCEqpCNNLTTGAHCEKCRTGYWGNPINGGKCQ 994
Cdd:cd00055     1 PCDCNGHGslsgQCDPGTgQCE--CKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
NanM super family cl34543
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
288-391 7.34e-06

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG3055:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 49.38  E-value: 7.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  288 SAHGAWSTVHPkhspAPAGSASHGATIWRDTLHIVGGESYGRGKLMStYDFNGNVWETVhpedgSEVPDKRYGASTVMYG 367
Cdd:COG3055   182 GFSNTWTTLAP----LPTARAGHAAAVLGGKILVFGGESGFSDEVEA-YDPATNTWTAL-----GELPTPRHGHAAVLTD 251

                          90       100
                  ....*....|....*....|....
gi 442621415  368 DKIFMYGGVVKGHGISNELWAFDV 391
Cdd:COG3055   252 GKVYVIGGETKPGVRTPLVTSAEV 275
PSI pfam01437
Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The ...
 821-870 2.14e-05

Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The function of the repeat is unknown. Three copies of the repeat are found Plexin. Two copies of the repeat are found in mahogany protein. A related C. elegans protein contains four copies of the repeat. The Met receptor contains a single copy of the repeat. The Pfam alignment shows 6 conserved cysteine residues that may form three conserved disulphide bridges, whereas some members show 8 conserved cysteines. The pattern of conservation suggests that cysteines 5 and 7 (that are not absolutely conserved) form a disulphide bridge (Personal observation. A Bateman).


:

Pssm-ID: 396154 [Multi-domain]  Cd Length: 52  Bit Score: 43.08  E-value: 2.14e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 442621415   821 SCASLTNCQNCTED---ECIWCQNEQRCVDRNAYtaSFPYGQCREWTTFTAKC 870
Cdd:pfam01437    1 RCSQYTSCSSCLAArdpYCGWCSSEGRCVRRSAC--GAPEGNCEEWEQASSKC 51
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 995-1040 2.93e-05

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


:

Pssm-ID: 238012  Cd Length: 50  Bit Score: 42.73  E-value: 2.93e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 442621415  995 RCDCNGQG---VYCHPDTGKCFCtTKGIVGDHCEKCdsQNHYHGDPLKG 1040
Cdd:cd00055     1 PCDCNGHGslsGQCDPGTGQCEC-KPNTTGRRCDRC--APGYYGLPSQG 46
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
343-614 3.88e-22

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 97.92  E-value: 3.88e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  343 WETVHPedgseVPDKRYGASTVMYGDKIFMYGGVVKGhGISNELWAFDVSARTWaniSVRADPscnatggttamcgPLHV 422
Cdd:COG3055     3 WSSLPD-----LPTPRSEAAAALLDGKVYVAGGLSGG-SASNSFEVYDPATNTW---SELAPL-------------PGPP 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  423 VGHTATLVpgYGDKnnyqymVVIFG----HSPNYGYLNTVQEFNFASREWRIVPTTGyvvKGGYGHSAAydFLTEKVYVY 498
Cdd:COG3055    61 RHHAAAVA--QDGK------LYVFGgftgANPSSTPLNDVYVYDPATNTWTKLAPMP---TPRGGATAL--LLDGKIYVV 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  499 GGIVSESESSQVlssrlYAYEPATRVWSLLSAAPSARLLHTANFVNQGLMMVFGGNTHNDTSQSY--------------- 563
Cdd:COG3055   128 GGWDDGGNVAWV-----EVYDPATGTWTQLAPLPTPRDHLAAAVLPDGKILVIGGRNGSGFSNTWttlaplptaraghaa 202

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442621415  564 -----------GAKCYSQDLLVYDVYCDSWHYHP-MPghlqadLARFGHSSVVFEESLYIYGG 614
Cdd:COG3055   203 avlggkilvfgGESGFSDEVEAYDPATNTWTALGeLP------TPRHGHAAVLTDGKVYVIGG 259
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 86-212 7.36e-14

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 68.98  E-value: 7.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415   86 CGGKVRmYHPMGTIH-DGW-GNYSVSVKCSWLIDARHPHwnrrhntnpsrtaNIRIHLREFATE----CGWDHLYIYDGD 159
Cdd:cd00041     1 CGGTLT-ASTSGTISsPNYpNNYPNNLNCVWTIEAPPGY-------------RIRLTFEDFDLEsspnCSYDYLEIYDGP 66

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 442621415  160 SVDSPLLAVFSGLmyrgnfsiRRVPQVIATSGTALVHFFSDDAYNMSGFNLTY 212
Cdd:cd00041    67 STSSPLLGRFCGS--------TLPPPIISSGNSLTVRFRSDSSVTGRGFKATY 111
PLN02153 PLN02153
epithiospecifier protein
 290-582 8.47e-11

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 65.01  E-value: 8.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  290 HGAWSTVHPKHSPAPAGSASHGATIWRDTLHIVGGE---SYGRGKLMSTYDFNGNVWeTVHPEDGSEVPDKRYGASTVMY 366
Cdd:PLN02153    6 QGGWIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGGElkpNEHIDKDLYVFDFNTHTW-SIAPANGDVPRISCLGVRMVAV 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  367 GDKIFMYGGVVKGHGISNeLWAFDVSARTWANISvradpSCNATGGTTAMcgplhvVGHTATlvpgyGDKNNyqymVVIF 446
Cdd:PLN02153   85 GTKLYIFGGRDEKREFSD-FYSYDTVKNEWTFLT-----KLDEEGGPEAR------TFHSMA-----SDENH----VYVF 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  447 GHSPNYGYLN------TVQEFNFASREWRIVPTTG--YVVKGGYGHSAAYDflteKVYVYGGIVSES---ESSQVLSSRL 515
Cdd:PLN02153  144 GGVSKGGLMKtperfrTIEAYNIADGKWVQLPDPGenFEKRGGAGFAVVQG----KIWVVYGFATSIlpgGKSDYESNAV 219

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  516 YAYEPATRVWSLLS---AAPSARLLHTANFVNQgLMMVFGGNTHNDTSQSYGAKCYSQDLLVYDVYCDSW 582
Cdd:PLN02153  220 QFFDPASGKWTEVEttgAKPSARSVFAHAVVGK-YIIIFGGEVWPDLKGHLGPGTLSNEGYALDTETLVW 288
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 104-212 1.48e-10

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 59.33  E-value: 1.48e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415    104 GNYSVSVKCSWLIdarHPHWNRRhntnpsrtanIRIHLREFATE----CGWDHLYIYDGDSVDSPLLAVFSGlmyrgnfs 179
Cdd:smart00042   10 QSYPNNLDCVWTI---RAPPGYR----------IELQFTDFDLEssdnCEYDYVEIYDGPSASSPLLGRFCG-------- 68

                            90       100       110
                    ....*....|....*....|....*....|....
gi 442621415    180 IRRVPQVIATSG-TALVHFFSDDAYNMSGFNLTY 212
Cdd:smart00042   69 SEAPPPVISSSSnSLTLTFVSDSSVQKRGFSARY 102
CUB pfam00431
CUB domain;
86-212 6.15e-09

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 54.99  E-value: 6.15e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415    86 CGGKVRmyHPMGTIH--DGWGNYSVSVKCSWLIDArhphwnrrhntnpsrTANIRIHLR------EFATECGWDHLYIYD 157
Cdd:pfam00431    1 CGGVLT--DSSGSISspNYPNPYPPNKDCVWLIRA---------------PPGFRVKLTfqdfelEDHDECGYDYVEIRD 63

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 442621415   158 GDSVDSPLLAVFSGLmyrgnfsiRRVPQVIATSGTALVHFFSDDAYNMSGFNLTY 212
Cdd:pfam00431   64 GPSASSPLLGRFCGS--------GIPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 948-994 1.03e-06

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 46.58  E-value: 1.03e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442621415  948 RCNCNGHS----YCNDQQ-HCEqpCNNLTTGAHCEKCRTGYWGNPINGGKCQ 994
Cdd:cd00055     1 PCDCNGHGslsgQCDPGTgQCE--CKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
288-391 7.34e-06

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 49.38  E-value: 7.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  288 SAHGAWSTVHPkhspAPAGSASHGATIWRDTLHIVGGESYGRGKLMStYDFNGNVWETVhpedgSEVPDKRYGASTVMYG 367
Cdd:COG3055   182 GFSNTWTTLAP----LPTARAGHAAAVLGGKILVFGGESGFSDEVEA-YDPATNTWTAL-----GELPTPRHGHAAVLTD 251

                          90       100
                  ....*....|....*....|....
gi 442621415  368 DKIFMYGGVVKGHGISNELWAFDV 391
Cdd:COG3055   252 GKVYVIGGETKPGVRTPLVTSAEV 275
PSI pfam01437
Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The ...
 821-870 2.14e-05

Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The function of the repeat is unknown. Three copies of the repeat are found Plexin. Two copies of the repeat are found in mahogany protein. A related C. elegans protein contains four copies of the repeat. The Met receptor contains a single copy of the repeat. The Pfam alignment shows 6 conserved cysteine residues that may form three conserved disulphide bridges, whereas some members show 8 conserved cysteines. The pattern of conservation suggests that cysteines 5 and 7 (that are not absolutely conserved) form a disulphide bridge (Personal observation. A Bateman).


Pssm-ID: 396154 [Multi-domain]  Cd Length: 52  Bit Score: 43.08  E-value: 2.14e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 442621415   821 SCASLTNCQNCTED---ECIWCQNEQRCVDRNAYtaSFPYGQCREWTTFTAKC 870
Cdd:pfam01437    1 RCSQYTSCSSCLAArdpYCGWCSSEGRCVRRSAC--GAPEGNCEEWEQASSKC 51
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 995-1040 2.93e-05

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 42.73  E-value: 2.93e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 442621415  995 RCDCNGQG---VYCHPDTGKCFCtTKGIVGDHCEKCdsQNHYHGDPLKG 1040
Cdd:cd00055     1 PCDCNGHGslsGQCDPGTGQCEC-KPNTTGRRCDRC--APGYYGLPSQG 46
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 996-1037 1.17e-03

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 38.10  E-value: 1.17e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 442621415   996 CDCNGQGVY---CHPDTGKCFCTTkGIVGDHCEKCdsQNHYHGDP 1037
Cdd:pfam00053    1 CDCNPHGSLsdtCDPETGQCLCKP-GVTGRHCDRC--KPGYYGLP 42
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 949-991 1.23e-03

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 38.10  E-value: 1.23e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 442621415   949 CNCNGHSYCNDQqhCEQ-----PCNNLTTGAHCEKCRTGYWGNPINGG 991
Cdd:pfam00053    1 CDCNPHGSLSDT--CDPetgqcLCKPGVTGRHCDRCKPGYYGLPSDPP 46
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
996-1040 1.99e-03

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 37.29  E-value: 1.99e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 442621415    996 CDCNGQG---VYCHPDTGKCFCTTkGIVGDHCEKCdsQNHYHGDPLKG 1040
Cdd:smart00180    1 CDCDPGGsasGTCDPDTGQCECKP-NVTGRRCDRC--APGYYGDGPPG 45
Kelch_6 pfam13964
Kelch motif;
358-396 3.03e-03

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 36.93  E-value: 3.03e-03
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 442621415   358 RYGASTVMYGDKIFMYGGVVKGHGISNELWAFDVSARTW 396
Cdd:pfam13964    2 RTFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSW 40
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
343-614 3.88e-22

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 97.92  E-value: 3.88e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  343 WETVHPedgseVPDKRYGASTVMYGDKIFMYGGVVKGhGISNELWAFDVSARTWaniSVRADPscnatggttamcgPLHV 422
Cdd:COG3055     3 WSSLPD-----LPTPRSEAAAALLDGKVYVAGGLSGG-SASNSFEVYDPATNTW---SELAPL-------------PGPP 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  423 VGHTATLVpgYGDKnnyqymVVIFG----HSPNYGYLNTVQEFNFASREWRIVPTTGyvvKGGYGHSAAydFLTEKVYVY 498
Cdd:COG3055    61 RHHAAAVA--QDGK------LYVFGgftgANPSSTPLNDVYVYDPATNTWTKLAPMP---TPRGGATAL--LLDGKIYVV 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  499 GGIVSESESSQVlssrlYAYEPATRVWSLLSAAPSARLLHTANFVNQGLMMVFGGNTHNDTSQSY--------------- 563
Cdd:COG3055   128 GGWDDGGNVAWV-----EVYDPATGTWTQLAPLPTPRDHLAAAVLPDGKILVIGGRNGSGFSNTWttlaplptaraghaa 202

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442621415  564 -----------GAKCYSQDLLVYDVYCDSWHYHP-MPghlqadLARFGHSSVVFEESLYIYGG 614
Cdd:COG3055   203 avlggkilvfgGESGFSDEVEAYDPATNTWTALGeLP------TPRHGHAAVLTDGKVYVIGG 259
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
291-569 2.22e-14

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 75.19  E-value: 2.22e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  291 GAWSTVHPkhspAPAGSASHGATIWRDTLHIVGGESYGRGklMST---YDFNGNVWETVHPEDGSEvpdkRYGASTVMYG 367
Cdd:COG3055     1 ATWSSLPD----LPTPRSEAAAALLDGKVYVAGGLSGGSA--SNSfevYDPATNTWSELAPLPGPP----RHHAAAVAQD 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  368 DKIFMYGGVVKGHG---ISNELWAFDVSARTWanisvradpscnatggTTAMCGPLHVVGHTATLVPGYgdknnyqymVV 444
Cdd:COG3055    71 GKLYVFGGFTGANPsstPLNDVYVYDPATNTW----------------TKLAPMPTPRGGATALLLDGK---------IY 125

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  445 IFGHSPNYGYLNTVQEFNFASREWRivpTTGYVVKGGYGHSAAydFLTE-KVYVYGGIVSESESSQ-------------- 509
Cdd:COG3055   126 VVGGWDDGGNVAWVEVYDPATGTWT---QLAPLPTPRDHLAAA--VLPDgKILVIGGRNGSGFSNTwttlaplptaragh 200

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442621415  510 ---VLSSRLY-------------AYEPATRVWSLLSAAPSARLLHTAnFVNQGLMMVFGGNTHN--DTSQSYGAKCYS 569
Cdd:COG3055   201 aaaVLGGKILvfggesgfsdeveAYDPATNTWTALGELPTPRHGHAA-VLTDGKVYVIGGETKPgvRTPLVTSAEVYD 277
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 86-212 7.36e-14

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 68.98  E-value: 7.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415   86 CGGKVRmYHPMGTIH-DGW-GNYSVSVKCSWLIDARHPHwnrrhntnpsrtaNIRIHLREFATE----CGWDHLYIYDGD 159
Cdd:cd00041     1 CGGTLT-ASTSGTISsPNYpNNYPNNLNCVWTIEAPPGY-------------RIRLTFEDFDLEsspnCSYDYLEIYDGP 66

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 442621415  160 SVDSPLLAVFSGLmyrgnfsiRRVPQVIATSGTALVHFFSDDAYNMSGFNLTY 212
Cdd:cd00041    67 STSSPLLGRFCGS--------TLPPPIISSGNSLTVRFRSDSSVTGRGFKATY 111
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
494-628 7.66e-14

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 73.27  E-value: 7.66e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  494 KVYVYGGIVSESESSQVlssrlYAYEPATRVWSLLSAAPSARLLHTANFVNQGLMMVFGGNTHNDTSQSygakcYSQDLL 573
Cdd:COG3055    24 KVYVAGGLSGGSASNSF-----EVYDPATNTWSELAPLPGPPRHHAAAVAQDGKLYVFGGFTGANPSST-----PLNDVY 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 442621415  574 VYDVYCDSWHY-HPMPGhlqadlARFGHSSVVFEESLYIYGGFNGQ-LLNDMLRYQP 628
Cdd:COG3055    94 VYDPATNTWTKlAPMPT------PRGGATALLLDGKIYVVGGWDDGgNVAWVEVYDP 144
PLN02153 PLN02153
epithiospecifier protein
 290-582 8.47e-11

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 65.01  E-value: 8.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  290 HGAWSTVHPKHSPAPAGSASHGATIWRDTLHIVGGE---SYGRGKLMSTYDFNGNVWeTVHPEDGSEVPDKRYGASTVMY 366
Cdd:PLN02153    6 QGGWIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGGElkpNEHIDKDLYVFDFNTHTW-SIAPANGDVPRISCLGVRMVAV 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  367 GDKIFMYGGVVKGHGISNeLWAFDVSARTWANISvradpSCNATGGTTAMcgplhvVGHTATlvpgyGDKNNyqymVVIF 446
Cdd:PLN02153   85 GTKLYIFGGRDEKREFSD-FYSYDTVKNEWTFLT-----KLDEEGGPEAR------TFHSMA-----SDENH----VYVF 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  447 GHSPNYGYLN------TVQEFNFASREWRIVPTTG--YVVKGGYGHSAAYDflteKVYVYGGIVSES---ESSQVLSSRL 515
Cdd:PLN02153  144 GGVSKGGLMKtperfrTIEAYNIADGKWVQLPDPGenFEKRGGAGFAVVQG----KIWVVYGFATSIlpgGKSDYESNAV 219

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  516 YAYEPATRVWSLLS---AAPSARLLHTANFVNQgLMMVFGGNTHNDTSQSYGAKCYSQDLLVYDVYCDSW 582
Cdd:PLN02153  220 QFFDPASGKWTEVEttgAKPSARSVFAHAVVGK-YIIIFGGEVWPDLKGHLGPGTLSNEGYALDTETLVW 288
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 104-212 1.48e-10

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 59.33  E-value: 1.48e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415    104 GNYSVSVKCSWLIdarHPHWNRRhntnpsrtanIRIHLREFATE----CGWDHLYIYDGDSVDSPLLAVFSGlmyrgnfs 179
Cdd:smart00042   10 QSYPNNLDCVWTI---RAPPGYR----------IELQFTDFDLEssdnCEYDYVEIYDGPSASSPLLGRFCG-------- 68

                            90       100       110
                    ....*....|....*....|....*....|....
gi 442621415    180 IRRVPQVIATSG-TALVHFFSDDAYNMSGFNLTY 212
Cdd:smart00042   69 SEAPPPVISSSSnSLTLTFVSDSSVQKRGFSARY 102
CUB pfam00431
CUB domain;
86-212 6.15e-09

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 54.99  E-value: 6.15e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415    86 CGGKVRmyHPMGTIH--DGWGNYSVSVKCSWLIDArhphwnrrhntnpsrTANIRIHLR------EFATECGWDHLYIYD 157
Cdd:pfam00431    1 CGGVLT--DSSGSISspNYPNPYPPNKDCVWLIRA---------------PPGFRVKLTfqdfelEDHDECGYDYVEIRD 63

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 442621415   158 GDSVDSPLLAVFSGLmyrgnfsiRRVPQVIATSGTALVHFFSDDAYNMSGFNLTY 212
Cdd:pfam00431   64 GPSASSPLLGRFCGS--------GIPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
PHA03098 PHA03098
kelch-like protein; Provisional
 358-622 5.88e-07

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 54.00  E-value: 5.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  358 RYGASTVMYGDKIFMYGGVVKGHGISNELWAFDVSARTWANISVRADPSCNAtgGTTAMCGPLHVVGhtatlvpgyGDKN 437
Cdd:PHA03098  285 VYCFGSVVLNNVIYFIGGMNKNNLSVNSVVSYDTKTKSWNKVPELIYPRKNP--GVTVFNNRIYVIG---------GIYN 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  438 NyqymvvifghspnyGYLNTVQEFNFASREWRIVPTTGYvvkGGYGHSAAydFLTEKVYVYGGIVSESESSQVLSSrlya 517
Cdd:PHA03098  354 S--------------ISLNTVESWKPGESKWREEPPLIF---PRYNPCVV--NVNNLIYVIGGISKNDELLKTVEC---- 410

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  518 YEPATRVWSLLSAAPSARLLHTANFVNqGLMMVFGGNTHNDTSQSYGAkcysqdLLVYDVYCDSWHYHPMpghlqADLAR 597
Cdd:PHA03098  411 FSLNTNKWSKGSPLPISHYGGCAIYHD-GKIYVIGGISYIDNIKVYNI------VESYNPVTNKWTELSS-----LNFPR 478

                         250       260
                  ....*....|....*....|....*
gi 442621415  598 FGHSSVVFEESLYIYGGFNGQLLND 622
Cdd:PHA03098  479 INASLCIFNNKIYVVGGDKYEYYIN 503
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 948-994 1.03e-06

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 46.58  E-value: 1.03e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442621415  948 RCNCNGHS----YCNDQQ-HCEqpCNNLTTGAHCEKCRTGYWGNPINGGKCQ 994
Cdd:cd00055     1 PCDCNGHGslsgQCDPGTgQCE--CKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
288-391 7.34e-06

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 49.38  E-value: 7.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  288 SAHGAWSTVHPkhspAPAGSASHGATIWRDTLHIVGGESYGRGKLMStYDFNGNVWETVhpedgSEVPDKRYGASTVMYG 367
Cdd:COG3055   182 GFSNTWTTLAP----LPTARAGHAAAVLGGKILVFGGESGFSDEVEA-YDPATNTWTAL-----GELPTPRHGHAAVLTD 251

                          90       100
                  ....*....|....*....|....
gi 442621415  368 DKIFMYGGVVKGHGISNELWAFDV 391
Cdd:COG3055   252 GKVYVIGGETKPGVRTPLVTSAEV 275
PSI pfam01437
Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The ...
 821-870 2.14e-05

Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The function of the repeat is unknown. Three copies of the repeat are found Plexin. Two copies of the repeat are found in mahogany protein. A related C. elegans protein contains four copies of the repeat. The Met receptor contains a single copy of the repeat. The Pfam alignment shows 6 conserved cysteine residues that may form three conserved disulphide bridges, whereas some members show 8 conserved cysteines. The pattern of conservation suggests that cysteines 5 and 7 (that are not absolutely conserved) form a disulphide bridge (Personal observation. A Bateman).


Pssm-ID: 396154 [Multi-domain]  Cd Length: 52  Bit Score: 43.08  E-value: 2.14e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 442621415   821 SCASLTNCQNCTED---ECIWCQNEQRCVDRNAYtaSFPYGQCREWTTFTAKC 870
Cdd:pfam01437    1 RCSQYTSCSSCLAArdpYCGWCSSEGRCVRRSAC--GAPEGNCEEWEQASSKC 51
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
 995-1040 2.93e-05

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 42.73  E-value: 2.93e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 442621415  995 RCDCNGQG---VYCHPDTGKCFCtTKGIVGDHCEKCdsQNHYHGDPLKG 1040
Cdd:cd00055     1 PCDCNGHGslsGQCDPGTGQCEC-KPNTTGRRCDRC--APGYYGLPSQG 46
PLN02193 PLN02193
nitrile-specifier protein
 310-582 8.57e-04

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 43.41  E-value: 8.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  310 HGATIwrDTLHIVGGESygrgKLMSTYDFNGNvWETVhpEDGSEVPDKRYGASTVMYGDKIFMYGG-VVKGHGISNELWA 388
Cdd:PLN02193  127 HGRST--DVLHSLGAYI----SLPSTPKLLGK-WIKV--EQKGEGPGLRCSHGIAQVGNKIYSFGGeFTPNQPIDKHLYV 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  389 FDVSARTWAnISvradpscNATGGTTAM-CGPLHVVGHTATLVPGYGDKNNYQYmvvifghspnygylNTVQEFNFASRE 467
Cdd:PLN02193  198 FDLETRTWS-IS-------PATGDVPHLsCLGVRMVSIGSTLYVFGGRDASRQY--------------NGFYSFDTTTNE 255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  468 WRIVPTTGYVVKGGYGHSAAYDflTEKVYVYGGIvseseSSQVLSSRLYAYEPATRVW---SLLSAAPSARLLHTANFVN 544
Cdd:PLN02193  256 WKLLTPVEEGPTPRSFHSMAAD--EENVYVFGGV-----SATARLKTLDSYNIVDKKWfhcSTPGDSFSIRGGAGLEVVQ 328

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 442621415  545 QGLMMVFGGNthndtsqsygaKCYSQDLLVYDVYCDSW 582
Cdd:PLN02193  329 GKVWVVYGFN-----------GCEVDDVHYYDPVQDKW 355
PLN02193 PLN02193
nitrile-specifier protein
 461-628 1.15e-03

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 43.02  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  461 FNFASREWRIVPTTGYVvkggyGHSAAYDF----LTEKVYVYGGivsESESSQVlsSRLYAYEPATRVWSLLSA---APS 533
Cdd:PLN02193  198 FDLETRTWSISPATGDV-----PHLSCLGVrmvsIGSTLYVFGG---RDASRQY--NGFYSFDTTTNEWKLLTPveeGPT 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  534 ARLLHTANfVNQGLMMVFGGnthndtsqsYGAKCYSQDLLVYDVYCDSWHYHPMPGhlQADLARFGHSSVVFEESLYIYG 613
Cdd:PLN02193  268 PRSFHSMA-ADEENVYVFGG---------VSATARLKTLDSYNIVDKKWFHCSTPG--DSFSIRGGAGLEVVQGKVWVVY 335

                         170
                  ....*....|....*
gi 442621415  614 GFNGQLLNDMLRYQP 628
Cdd:PLN02193  336 GFNGCEVDDVHYYDP 350
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 996-1037 1.17e-03

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 38.10  E-value: 1.17e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 442621415   996 CDCNGQGVY---CHPDTGKCFCTTkGIVGDHCEKCdsQNHYHGDP 1037
Cdd:pfam00053    1 CDCNPHGSLsdtCDPETGQCLCKP-GVTGRHCDRC--KPGYYGLP 42
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
 949-991 1.23e-03

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 38.10  E-value: 1.23e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 442621415   949 CNCNGHSYCNDQqhCEQ-----PCNNLTTGAHCEKCRTGYWGNPINGG 991
Cdd:pfam00053    1 CDCNPHGSLSDT--CDPetgqcLCKPGVTGRHCDRCKPGYYGLPSDPP 46
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
996-1040 1.99e-03

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 37.29  E-value: 1.99e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 442621415    996 CDCNGQG---VYCHPDTGKCFCTTkGIVGDHCEKCdsQNHYHGDPLKG 1040
Cdd:smart00180    1 CDCDPGGsasGTCDPDTGQCECKP-NVTGRRCDRC--APGYYGDGPPG 45
Kelch_6 pfam13964
Kelch motif;
358-396 3.03e-03

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 36.93  E-value: 3.03e-03
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 442621415   358 RYGASTVMYGDKIFMYGGVVKGHGISNELWAFDVSARTW 396
Cdd:pfam13964    2 RTFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSW 40
Kelch_3 pfam13415
Galactose oxidase, central domain;
492-543 4.75e-03

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 36.50  E-value: 4.75e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 442621415   492 TEKVYVYGGIvseSESSQVLSSRLYAYEPATRVWSLLSAAPSARLLHTANFV 543
Cdd:pfam13415    1 GDKLYIFGGL---GFDGQTRLNDLYVYDLDTNTWTQIGDLPPPRSGHSATYI 49
PHA03098 PHA03098
kelch-like protein; Provisional
 311-510 5.41e-03

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 40.91  E-value: 5.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  311 GATIWRDTLHIVGGESYGRG-KLMSTYDFNGNVWETVHPedgseVPDKRYGASTVMYGDKIFMYGGVVKGHGISNELWAF 389
Cdd:PHA03098  337 GVTVFNNRIYVIGGIYNSISlNTVESWKPGESKWREEPP-----LIFPRYNPCVVNVNNLIYVIGGISKNDELLKTVECF 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442621415  390 DVSARTWANISvradpscnatggttamCGPLHVVGHTATLvpgygdKNNYQYMVVIFGHSPNYGYLNTVQEFNFASREWR 469
Cdd:PHA03098  412 SLNTNKWSKGS----------------PLPISHYGGCAIY------HDGKIYVIGGISYIDNIKVYNIVESYNPVTNKWT 469

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 442621415  470 IVPTTGYVVKggyghSAAYDFLTEKVYVYGGIVSESESSQV 510
Cdd:PHA03098  470 ELSSLNFPRI-----NASLCIFNNKIYVVGGDKYEYYINEI 505
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 355-391 5.79e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 36.00  E-value: 5.79e-03
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 442621415   355 PDKRYGASTVMYGDKIFMYGGVV-KGHGISNELWAFDV 391
Cdd:pfam13854    1 PVPRYGHCAVTVGDYIYLYGGYTgGEGQPSDDVYVLSL 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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