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Conserved domains on  [gi|442619352|ref|NP_001262621|]
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pannier, isoform D [Drosophila melanogaster]

Protein Classification

GATA-type transcription factor( domain architecture ID 10078896)

GATA-type transcription factor binds to the DNA consensus sequence [AT]GATA[AG] and may function as a transcription factor/regulator

CATH:  3.30.50.10
Gene Ontology:  GO:0003700|GO:0006357|GO:0008270|GO:0043565
PubMed:  31574210
SCOP:  4003617

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 174-224 2.60e-22

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 89.74  E-value: 2.60e-22
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 442619352 174 CTNCGTRTTTLWRRN-NDGEPVCNACGLYYKLHGVNRPLAMRK-DGIQTRKRK 224
Cdd:cd00202    2 CSNCGTTTTPLWRRGpSGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 116-160 1.34e-17

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 76.64  E-value: 1.34e-17
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 442619352 116 ECVNCGAISTPLWRRDG-TGHYLCNACGLYHKMNGMNRPLIKPSKR 160
Cdd:cd00202    1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKD 46
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 174-224 2.60e-22

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 89.74  E-value: 2.60e-22
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 442619352 174 CTNCGTRTTTLWRRN-NDGEPVCNACGLYYKLHGVNRPLAMRK-DGIQTRKRK 224
Cdd:cd00202    2 CSNCGTTTTPLWRRGpSGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
169-218 1.71e-18

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 79.00  E-value: 1.71e-18
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 442619352   169 RMGLCCTNCGTRTTTLWRRNNDGE-PVCNACGLYYKLHGV-NRPLAMRKDGI 218
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGlKRPLSLKKDGI 52
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 116-160 1.34e-17

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 76.64  E-value: 1.34e-17
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 442619352 116 ECVNCGAISTPLWRRDG-TGHYLCNACGLYHKMNGMNRPLIKPSKR 160
Cdd:cd00202    1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKD 46
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
112-160 2.12e-14

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 67.44  E-value: 2.12e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 442619352   112 GEGRECVNCGAISTPLWRRDGTGH-YLCNACGLYHKMNG-MNRPLIKPSKR 160
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGgLKRPLSLKKDG 51
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 174-208 3.89e-13

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 63.49  E-value: 3.89e-13
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 442619352  174 CTNCGTRTTTLWRRNNDGEP-VCNACGLYYKLHGVN 208
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGLK 36
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 117-149 1.20e-11

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 59.25  E-value: 1.20e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 442619352  117 CVNCGAISTPLWRRDGTGHY-LCNACGLYHKMNG 149
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKG 34
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
119-286 1.34e-08

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 57.19  E-value: 1.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442619352 119 NCGAISTPLWRR-DGTGHYLCNACGLYHKMNGMNRPLIKPSKrlvsaTATRRMGLCCTNCGTRTTTlwrRNNDGEPVCNA 197
Cdd:COG5641  303 LTTSTATPLWRRtSDKSSFSCNASGSALKPPGSKRPLLPKPD-----PNSKRSNATCMNCSSTPTN---KILSPPTTSNS 374

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442619352 198 CGLYYKLHGVNRPLAMRKDGIQTRKRKPKKTGSGSAVGAGTGSGTGSTL-EAIKECKEEHDLKPSLSLERHSLSKLHTDm 276
Cdd:COG5641  375 PGAQVKLPNQTRSTGATKKKITRRRMNSGKIPALSSSMKNPVPKEFSPLiPQSTESETPSQSKSSLTSKLEEFESLSLL- 453

                        170
                 ....*....|
gi 442619352 277 KSGTSSSSTL 286
Cdd:COG5641  454 KSVSSMMNLE 463
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 174-224 2.60e-22

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 89.74  E-value: 2.60e-22
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 442619352 174 CTNCGTRTTTLWRRN-NDGEPVCNACGLYYKLHGVNRPLAMRK-DGIQTRKRK 224
Cdd:cd00202    2 CSNCGTTTTPLWRRGpSGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
169-218 1.71e-18

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 79.00  E-value: 1.71e-18
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 442619352   169 RMGLCCTNCGTRTTTLWRRNNDGE-PVCNACGLYYKLHGV-NRPLAMRKDGI 218
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGlKRPLSLKKDGI 52
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 116-160 1.34e-17

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 76.64  E-value: 1.34e-17
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 442619352 116 ECVNCGAISTPLWRRDG-TGHYLCNACGLYHKMNGMNRPLIKPSKR 160
Cdd:cd00202    1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKKD 46
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
112-160 2.12e-14

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 67.44  E-value: 2.12e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 442619352   112 GEGRECVNCGAISTPLWRRDGTGH-YLCNACGLYHKMNG-MNRPLIKPSKR 160
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGgLKRPLSLKKDG 51
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 174-208 3.89e-13

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 63.49  E-value: 3.89e-13
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 442619352  174 CTNCGTRTTTLWRRNNDGEP-VCNACGLYYKLHGVN 208
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGLK 36
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 117-149 1.20e-11

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 59.25  E-value: 1.20e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 442619352  117 CVNCGAISTPLWRRDGTGHY-LCNACGLYHKMNG 149
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKG 34
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
119-286 1.34e-08

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 57.19  E-value: 1.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442619352 119 NCGAISTPLWRR-DGTGHYLCNACGLYHKMNGMNRPLIKPSKrlvsaTATRRMGLCCTNCGTRTTTlwrRNNDGEPVCNA 197
Cdd:COG5641  303 LTTSTATPLWRRtSDKSSFSCNASGSALKPPGSKRPLLPKPD-----PNSKRSNATCMNCSSTPTN---KILSPPTTSNS 374

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442619352 198 CGLYYKLHGVNRPLAMRKDGIQTRKRKPKKTGSGSAVGAGTGSGTGSTL-EAIKECKEEHDLKPSLSLERHSLSKLHTDm 276
Cdd:COG5641  375 PGAQVKLPNQTRSTGATKKKITRRRMNSGKIPALSSSMKNPVPKEFSPLiPQSTESETPSQSKSSLTSKLEEFESLSLL- 453

                        170
                 ....*....|
gi 442619352 277 KSGTSSSSTL 286
Cdd:COG5641  454 KSVSSMMNLE 463
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
117-230 3.61e-08

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 55.65  E-value: 3.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442619352 117 CVNCGAISTPLWRRD-----GTGHYLCNACGLYHKMNGMNRPLIK----------------------------------- 156
Cdd:COG5641  161 CSNCKTTSTPLWRRAssessLPGNNLCNACGLYLKLHGSPRAPISlksdsiksrssrsshnnndsngenantesignssa 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442619352 157 -------------------------PSKRLVSATATRRMG-----------------LCCTNCG--TRTTTLWRRNNDGE 192
Cdd:COG5641  241 skltksweerpqgrqllsdagslspRSNNPKSPLLEGLMGstslqpvstpklvlpsdKKRSTLTtsTATPLWRRTSDKSS 320

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 442619352 193 PVCNACGLYYKLHGVNRPLAMRKDGIQTRKRKPKKTGS 230
Cdd:COG5641  321 FSCNASGSALKPPGSKRPLLPKPDPNSKRSNATCMNCS 358
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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