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Conserved domains on  [gi|442618665|ref|NP_001262490|]
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glutamate carrier 1, isoform B [Drosophila melanogaster]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 37-294 5.75e-21

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 90.98  E-value: 5.75e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665  37 TCVFPLDLVKTRLQNQQIGPNGER----MYNSMFDCFRKTYKAEGYFGMYRGSGVNILLITPEKAIKLTANDYFRHKLTT 112
Cdd:PTZ00169  23 TAVAPIERVKMLIQTQDSIPEIKSgkvpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNFAFKDYFKNMFPK 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665 113 KDGKLPLT----SQMVAGGLAGAFQIIVTTPMELLKIQM-QDAGRvaaaaklaGKTVEKVSATQLASQLIKDKGIFGLYK 187
Cdd:PTZ00169 103 YNQKTDFWkffgVNILSGGLAGASSLLIVYPLDFARTRLaSDIGK--------GGDREFTGLFDCLMKISKQTGFLSLYQ 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665 188 GIGATGLRDVTFSIIYFPLFATLNDLGPRRNDGSGEAVFWcsFLAGlAAGSTAALAVNPFDVVKTR--LQAIKKADGEKE 265
Cdd:PTZ00169 175 GFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNILYKW--AVAQ-TVTILAGLISYPFDTVRRRmmMMSGRKAKSEIQ 251

                        250       260
                 ....*....|....*....|....*....
gi 442618665 266 FKGISDCITKTLKHEGPTAFFKGGLCRMI 294
Cdd:PTZ00169 252 YTGTLDCWKKILKNEGLGGFFKGAWANVL 280
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 37-294 5.75e-21

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 90.98  E-value: 5.75e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665  37 TCVFPLDLVKTRLQNQQIGPNGER----MYNSMFDCFRKTYKAEGYFGMYRGSGVNILLITPEKAIKLTANDYFRHKLTT 112
Cdd:PTZ00169  23 TAVAPIERVKMLIQTQDSIPEIKSgkvpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNFAFKDYFKNMFPK 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665 113 KDGKLPLT----SQMVAGGLAGAFQIIVTTPMELLKIQM-QDAGRvaaaaklaGKTVEKVSATQLASQLIKDKGIFGLYK 187
Cdd:PTZ00169 103 YNQKTDFWkffgVNILSGGLAGASSLLIVYPLDFARTRLaSDIGK--------GGDREFTGLFDCLMKISKQTGFLSLYQ 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665 188 GIGATGLRDVTFSIIYFPLFATLNDLGPRRNDGSGEAVFWcsFLAGlAAGSTAALAVNPFDVVKTR--LQAIKKADGEKE 265
Cdd:PTZ00169 175 GFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNILYKW--AVAQ-TVTILAGLISYPFDTVRRRmmMMSGRKAKSEIQ 251

                        250       260
                 ....*....|....*....|....*....
gi 442618665 266 FKGISDCITKTLKHEGPTAFFKGGLCRMI 294
Cdd:PTZ00169 252 YTGTLDCWKKILKNEGLGGFFKGAWANVL 280
Mito_carr pfam00153
Mitochondrial carrier protein;
226-307 8.90e-20

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 82.32  E-value: 8.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665  226 FWCSFLAGLAAGSTAALAVNPFDVVKTRLQAiKKADGEKEFKGISDCITKTLKHEGPTAFFKGGLCRMIVIAPLFGIAQT 305
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQV-QGGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFG 83


                  ..
gi 442618665  306 VY 307
Cdd:pfam00153  84 TY 85
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 37-294 5.75e-21

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 90.98  E-value: 5.75e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665  37 TCVFPLDLVKTRLQNQQIGPNGER----MYNSMFDCFRKTYKAEGYFGMYRGSGVNILLITPEKAIKLTANDYFRHKLTT 112
Cdd:PTZ00169  23 TAVAPIERVKMLIQTQDSIPEIKSgkvpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNFAFKDYFKNMFPK 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665 113 KDGKLPLT----SQMVAGGLAGAFQIIVTTPMELLKIQM-QDAGRvaaaaklaGKTVEKVSATQLASQLIKDKGIFGLYK 187
Cdd:PTZ00169 103 YNQKTDFWkffgVNILSGGLAGASSLLIVYPLDFARTRLaSDIGK--------GGDREFTGLFDCLMKISKQTGFLSLYQ 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665 188 GIGATGLRDVTFSIIYFPLFATLNDLGPRRNDGSGEAVFWcsFLAGlAAGSTAALAVNPFDVVKTR--LQAIKKADGEKE 265
Cdd:PTZ00169 175 GFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNILYKW--AVAQ-TVTILAGLISYPFDTVRRRmmMMSGRKAKSEIQ 251

                        250       260
                 ....*....|....*....|....*....
gi 442618665 266 FKGISDCITKTLKHEGPTAFFKGGLCRMI 294
Cdd:PTZ00169 252 YTGTLDCWKKILKNEGLGGFFKGAWANVL 280
Mito_carr pfam00153
Mitochondrial carrier protein;
226-307 8.90e-20

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 82.32  E-value: 8.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665  226 FWCSFLAGLAAGSTAALAVNPFDVVKTRLQAiKKADGEKEFKGISDCITKTLKHEGPTAFFKGGLCRMIVIAPLFGIAQT 305
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQV-QGGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFG 83


                  ..
gi 442618665  306 VY 307
Cdd:pfam00153  84 TY 85
Mito_carr pfam00153
Mitochondrial carrier protein;
36-113 2.34e-19

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 81.16  E-value: 2.34e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442618665   36 VTCVFPLDLVKTRLQNQQIGPNGErmYNSMFDCFRKTYKAEGYFGMYRGSGVNILLITPEKAIKLTANDYFRHKLTTK 113
Cdd:pfam00153  20 VTVTYPLDVVKTRLQVQGGSGKSK--GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTYETLKRLLLKK 95
Mito_carr pfam00153
Mitochondrial carrier protein;
115-213 4.27e-14

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 66.91  E-value: 4.27e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665  115 GKLPLTSQMVAGGLAGAFQIIVTTPMELLKIQMQDAGRVAAAaklagktvEKVSATQLASQLIKDKGIFGLYKGIGATGL 194
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKS--------KGRGILDCFKKIYKEEGIRGLYKGLLPNLL 72

                          90
                  ....*....|....*....
gi 442618665  195 RDVTFSIIYFPLFATLNDL 213
Cdd:pfam00153  73 RVAPAAAIYFGTYETLKRL 91
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 113-288 4.17e-10

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 59.78  E-value: 4.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665 113 KDGKLPLTSQMVAGGLAGAFQIIVTTPMELLK--IQMQDAgrvaAAAKLAGKTVEKVSATQLASQLIKDKGIFGLYKGig 190
Cdd:PTZ00169   1 MDKKTNFATDFLMGGISAAISKTAVAPIERVKmlIQTQDS----IPEIKSGKVPRYSGIVNCFRRVSKEQGVLSLWRG-- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442618665 191 atglrDVTFSIIYFPL----FA---TLNDLGPRRNDGSGEAVFWC-SFLAGLAAGSTAALAVNPFDVVKTRLQAIKKADG 262
Cdd:PTZ00169  75 -----NTANVIRYFPTqafnFAfkdYFKNMFPKYNQKTDFWKFFGvNILSGGLAGASSLLIVYPLDFARTRLASDIGKGG 149

                        170       180
                 ....*....|....*....|....*.
gi 442618665 263 EKEFKGISDCITKTLKHEGPTAFFKG 288
Cdd:PTZ00169 150 DREFTGLFDCLMKISKQTGFLSLYQG 175
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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