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Conserved domains on  [gi|442633950|ref|NP_001262165|]
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M6, isoform E [Drosophila melanogaster]

Protein Classification

myelin proteolipid family protein( domain architecture ID 10472648)

myelin proteolipid family protein similar to human myelin proteolipid protein (PLP) that plays an important role in the formation or maintenance of the multilamellar structure of myelin

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Myelin_PLP pfam01275
Myelin proteolipid protein (PLP or lipophilin);
51-274 9.84e-101

Myelin proteolipid protein (PLP or lipophilin);


:

Pssm-ID: 460144  Cd Length: 231  Bit Score: 294.59  E-value: 9.84e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442633950   51 GECCQSCMARIPYATLIATLMCLLGVGIFCFTMYRGASLTVIMVDQVFH-------LRLIWIEAVQMIFVIIGAGMAALG 123
Cdd:pfam01275   1 YDCCVRCLGRVPYASLIATILCFAGVALFCGCGHRALTLTVLMLETVFHrnyqdyeLLATWIDAFQYVIYGIAAFFFLLG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442633950  124 FMILFVGFLATGATRyKVYRAWRSRVGGRISCAVLMGITYLLNFVWSLILCFLVVVTFIYTMFWNMCTSV---EHSQSCI 200
Cdd:pfam01275  81 LLLLAEGFLTTGATK-QVYGAFRSTVGGRCSCAVFMGITYVLALVWLLVFAFLAIPVFIFTNFWSTCQNInvlSTNQLCI 159
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442633950  201 DLTQFHFMFPPNTkleDMKVCEKYEIKAFCKDGVENAEV-MFILATLSTLLVLLSLVHYLMCLSANYAHIRDHEK 274
Cdd:pfam01275 160 DFRQFGFLPWNAT---PGKVCGMTELKAFCKDYEEKMTFhLFILAFAGAGATLLALVHYLMCLTANYAHLRDHGR 231
 
Name Accession Description Interval E-value
Myelin_PLP pfam01275
Myelin proteolipid protein (PLP or lipophilin);
51-274 9.84e-101

Myelin proteolipid protein (PLP or lipophilin);


Pssm-ID: 460144  Cd Length: 231  Bit Score: 294.59  E-value: 9.84e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442633950   51 GECCQSCMARIPYATLIATLMCLLGVGIFCFTMYRGASLTVIMVDQVFH-------LRLIWIEAVQMIFVIIGAGMAALG 123
Cdd:pfam01275   1 YDCCVRCLGRVPYASLIATILCFAGVALFCGCGHRALTLTVLMLETVFHrnyqdyeLLATWIDAFQYVIYGIAAFFFLLG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442633950  124 FMILFVGFLATGATRyKVYRAWRSRVGGRISCAVLMGITYLLNFVWSLILCFLVVVTFIYTMFWNMCTSV---EHSQSCI 200
Cdd:pfam01275  81 LLLLAEGFLTTGATK-QVYGAFRSTVGGRCSCAVFMGITYVLALVWLLVFAFLAIPVFIFTNFWSTCQNInvlSTNQLCI 159
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442633950  201 DLTQFHFMFPPNTkleDMKVCEKYEIKAFCKDGVENAEV-MFILATLSTLLVLLSLVHYLMCLSANYAHIRDHEK 274
Cdd:pfam01275 160 DFRQFGFLPWNAT---PGKVCGMTELKAFCKDYEEKMTFhLFILAFAGAGATLLALVHYLMCLTANYAHLRDHGR 231
 
Name Accession Description Interval E-value
Myelin_PLP pfam01275
Myelin proteolipid protein (PLP or lipophilin);
51-274 9.84e-101

Myelin proteolipid protein (PLP or lipophilin);


Pssm-ID: 460144  Cd Length: 231  Bit Score: 294.59  E-value: 9.84e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442633950   51 GECCQSCMARIPYATLIATLMCLLGVGIFCFTMYRGASLTVIMVDQVFH-------LRLIWIEAVQMIFVIIGAGMAALG 123
Cdd:pfam01275   1 YDCCVRCLGRVPYASLIATILCFAGVALFCGCGHRALTLTVLMLETVFHrnyqdyeLLATWIDAFQYVIYGIAAFFFLLG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442633950  124 FMILFVGFLATGATRyKVYRAWRSRVGGRISCAVLMGITYLLNFVWSLILCFLVVVTFIYTMFWNMCTSV---EHSQSCI 200
Cdd:pfam01275  81 LLLLAEGFLTTGATK-QVYGAFRSTVGGRCSCAVFMGITYVLALVWLLVFAFLAIPVFIFTNFWSTCQNInvlSTNQLCI 159
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442633950  201 DLTQFHFMFPPNTkleDMKVCEKYEIKAFCKDGVENAEV-MFILATLSTLLVLLSLVHYLMCLSANYAHIRDHEK 274
Cdd:pfam01275 160 DFRQFGFLPWNAT---PGKVCGMTELKAFCKDYEEKMTFhLFILAFAGAGATLLALVHYLMCLTANYAHLRDHGR 231
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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