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Conserved domains on  [gi|442630662|ref|NP_001261497|]
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cornetto, isoform E [Drosophila melanogaster]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 340-627 1.76e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 1.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   340 ETAVQTALTS-EDLEQVLGggLLQTRAVDAvEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELHLN 418
Cdd:TIGR02168  697 EKALAELRKElEELEEELE--QLRKELEEL-SRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA 773

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   419 TERvmgmLELARVVSASAGTPTSEDSgdgsghDSLLMLESQIQISGHELFERQQEIGQLRSMCRALQlemRRSLATQQLL 498
Cdd:TIGR02168  774 EEE----LAEAEAEIEELEAQIEQLK------EELKALREALDELRAELTLLNEEAANLRERLESLE---RRIAATERRL 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   499 LQEKAAIEQESSELQDfLQHEKAAQCDALRDLEADYQAVKLQLANREEEAKVLRDEcrhlvrlNEQRRQENRLLQTKFTA 578
Cdd:TIGR02168  841 EDLEEQIEELSEDIES-LAAEIEELEELIEELESELEALLNERASLEEALALLRSE-------LEELSEELRELESKRSE 912

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 442630662   579 LENKSRELihqqNASVAGASTALSGLHSRLDGLVEQLVYSYSISEQDLE 627
Cdd:TIGR02168  913 LRRELEEL----REKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAE 957
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 92-336 2.20e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 2.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   92 VTTVAQTPSETGSEKTSPPRRTGSVKKkvAMFEPEPTGTPAKDQLRGRVANLkraESLPRNSAAPGTPGTPSTHRDKA-- 169
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPSRLAP--AILPDEPVGEPVHPRMLTWIRGL---EELASDDAGDPPPPLPPAAPPAApd 2565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  170 RLSTSSFRVPSTTGTPSSSRLARPQKPdtlpnalnraqsvqrltqvqrtPSLSRARTPGTPSDDGRWPANRGAARRGMSV 249
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPAVTSRARRPDAP----------------------PQSARPRAPVDDRGDPRGPAPPSPLPPDTHA 2623

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  250 -TPEVTTNRMRGSPAPGG-TLPRRRKQQSVEDLTGGRLSRSNSISRAAivDARMTSSVMVVPTsRRSLAPAAAKVNSLRR 327
Cdd:PHA03247 2624 pDPPPPSPSPAANEPDPHpPPTVPPPERPRDDPAPGRVSRPRRARRLG--RAAQASSPPQRPR-RRAARPTVGSLTSLAD 2700

                         250
                  ....*....|.
gi 442630662  328 P--QPATPRTR 336
Cdd:PHA03247 2701 PppPPPTPEPA 2711
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 340-627 1.76e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 1.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   340 ETAVQTALTS-EDLEQVLGggLLQTRAVDAvEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELHLN 418
Cdd:TIGR02168  697 EKALAELRKElEELEEELE--QLRKELEEL-SRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA 773

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   419 TERvmgmLELARVVSASAGTPTSEDSgdgsghDSLLMLESQIQISGHELFERQQEIGQLRSMCRALQlemRRSLATQQLL 498
Cdd:TIGR02168  774 EEE----LAEAEAEIEELEAQIEQLK------EELKALREALDELRAELTLLNEEAANLRERLESLE---RRIAATERRL 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   499 LQEKAAIEQESSELQDfLQHEKAAQCDALRDLEADYQAVKLQLANREEEAKVLRDEcrhlvrlNEQRRQENRLLQTKFTA 578
Cdd:TIGR02168  841 EDLEEQIEELSEDIES-LAAEIEELEELIEELESELEALLNERASLEEALALLRSE-------LEELSEELRELESKRSE 912

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 442630662   579 LENKSRELihqqNASVAGASTALSGLHSRLDGLVEQLVYSYSISEQDLE 627
Cdd:TIGR02168  913 LRRELEEL----REKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAE 957
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 361-615 9.98e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 9.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 361 LQTRAVDAVEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELHLNTERVmgmLELARVVSASAGTPT 440
Cdd:COG1196  229 LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIA 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 441 SEDSGDGSGHDSLLMLESQIQISGHELFERQQEIGQLRSMCRALQLEMRRSLAT----QQLLLQEKAAIEQESSELQDFL 516
Cdd:COG1196  306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAElaeaEEALLEAEAELAEAEEELEELA 385

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 517 QHEKAAQcDALRDLEADYQAVKLQLANREEEAKVLRDECRHL---VRLNEQRRQENRLLQTKFTALENKSRELIHQQNAS 593
Cdd:COG1196  386 EELLEAL-RAAAELAAQLEELEEAEEALLERLERLEEELEELeeaLAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                        250       260
                 ....*....|....*....|..
gi 442630662 594 VAGASTALSGLHSRLDGLVEQL 615
Cdd:COG1196  465 LAELLEEAALLEAALAELLEEL 486
PHA03247 PHA03247
large tegument protein UL36; Provisional
 92-336 2.20e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 2.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   92 VTTVAQTPSETGSEKTSPPRRTGSVKKkvAMFEPEPTGTPAKDQLRGRVANLkraESLPRNSAAPGTPGTPSTHRDKA-- 169
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPSRLAP--AILPDEPVGEPVHPRMLTWIRGL---EELASDDAGDPPPPLPPAAPPAApd 2565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  170 RLSTSSFRVPSTTGTPSSSRLARPQKPdtlpnalnraqsvqrltqvqrtPSLSRARTPGTPSDDGRWPANRGAARRGMSV 249
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPAVTSRARRPDAP----------------------PQSARPRAPVDDRGDPRGPAPPSPLPPDTHA 2623

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  250 -TPEVTTNRMRGSPAPGG-TLPRRRKQQSVEDLTGGRLSRSNSISRAAivDARMTSSVMVVPTsRRSLAPAAAKVNSLRR 327
Cdd:PHA03247 2624 pDPPPPSPSPAANEPDPHpPPTVPPPERPRDDPAPGRVSRPRRARRLG--RAAQASSPPQRPR-RRAARPTVGSLTSLAD 2700

                         250
                  ....*....|.
gi 442630662  328 P--QPATPRTR 336
Cdd:PHA03247 2701 PppPPPTPEPA 2711
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 382-570 1.36e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  382 QREFELEQLRHEVRQLsgKLQREREEKLAM-----------QQELHLNTERVMGMLELARVVSasagtptsedsgdgsgh 450
Cdd:pfam17380 345 ERERELERIRQEERKR--ELERIRQEEIAMeisrmrelerlQMERQQKNERVRQELEAARKVK----------------- 405

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  451 dsllMLESqiqisghelfERQQEIGQLRSMCRALQLEMRRSLATQQLLLQEKAAIEQESSELQDFlqhEKAAQCDALRDL 530
Cdd:pfam17380 406 ----ILEE----------ERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQ---ERQQQVERLRQQ 468

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 442630662  531 EADYQAVKLQLANREEEAKVLRDECRHLVrlnEQRRQENR 570
Cdd:pfam17380 469 EEERKRKKLELEKEKRDRKRAEEQRRKIL---EKELEERK 505
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 340-627 1.76e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 1.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   340 ETAVQTALTS-EDLEQVLGggLLQTRAVDAvEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELHLN 418
Cdd:TIGR02168  697 EKALAELRKElEELEEELE--QLRKELEEL-SRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA 773

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   419 TERvmgmLELARVVSASAGTPTSEDSgdgsghDSLLMLESQIQISGHELFERQQEIGQLRSMCRALQlemRRSLATQQLL 498
Cdd:TIGR02168  774 EEE----LAEAEAEIEELEAQIEQLK------EELKALREALDELRAELTLLNEEAANLRERLESLE---RRIAATERRL 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   499 LQEKAAIEQESSELQDfLQHEKAAQCDALRDLEADYQAVKLQLANREEEAKVLRDEcrhlvrlNEQRRQENRLLQTKFTA 578
Cdd:TIGR02168  841 EDLEEQIEELSEDIES-LAAEIEELEELIEELESELEALLNERASLEEALALLRSE-------LEELSEELRELESKRSE 912

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 442630662   579 LENKSRELihqqNASVAGASTALSGLHSRLDGLVEQLVYSYSISEQDLE 627
Cdd:TIGR02168  913 LRRELEEL----REKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAE 957
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 361-615 9.98e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 9.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 361 LQTRAVDAVEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELHLNTERVmgmLELARVVSASAGTPT 440
Cdd:COG1196  229 LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIA 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 441 SEDSGDGSGHDSLLMLESQIQISGHELFERQQEIGQLRSMCRALQLEMRRSLAT----QQLLLQEKAAIEQESSELQDFL 516
Cdd:COG1196  306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAElaeaEEALLEAEAELAEAEEELEELA 385

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 517 QHEKAAQcDALRDLEADYQAVKLQLANREEEAKVLRDECRHL---VRLNEQRRQENRLLQTKFTALENKSRELIHQQNAS 593
Cdd:COG1196  386 EELLEAL-RAAAELAAQLEELEEAEEALLERLERLEEELEELeeaLAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                        250       260
                 ....*....|....*....|..
gi 442630662 594 VAGASTALSGLHSRLDGLVEQL 615
Cdd:COG1196  465 LAELLEEAALLEAALAELLEEL 486
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 321-647 6.09e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.44  E-value: 6.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   321 KVNSLRRPQPATPRTRIYHE--TAVQTALTSEDLEQvLGGGLLQTR-AVDAVEQRNQSTQAEPDQREFELEQLRHEVRQL 397
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAelRELELALLVLRLEE-LREELEELQeELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   398 SGKLQREREEKLAMQQELhlntERVMGMLELARVVSASAGTPTSEDSGDgsghdsLLMLESQIQISGHELFERQQEIGQL 477
Cdd:TIGR02168  280 EEEIEELQKELYALANEI----SRLEQQKQILRERLANLERQLEELEAQ------LEELESKLDELAEELAELEEKLEEL 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   478 rsmcralqlemrrslatQQLLLQEKAAIEQESSELQDFLQHEKAAQcDALRDLEADYQAVKLQLANREEEAKVLRDECRH 557
Cdd:TIGR02168  350 -----------------KEELESLEAELEELEAELEELESRLEELE-EQLETLRSKVAQLELQIASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   558 LVRLNEQRRQENRLLQTKFTALEnksrelIHQQNASVAGASTALSGLHSRLDGLVEQLvYSYSISEQDLEDIRFQAETEH 637
Cdd:TIGR02168  412 LEDRRERLQQEIEELLKKLEEAE------LKELQAELEELEEELEELQEELERLEEAL-EELREELEEAEQALDAAEREL 484

                          330
                   ....*....|
gi 442630662   638 VQNGQRPNGL 647
Cdd:TIGR02168  485 AQLQARLDSL 494
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
361-543 2.17e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 2.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  361 LQTRAVDAVEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELHLNTERVmGMLELARvvsasagtpt 440
Cdd:COG4913   264 YAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEL-DELEAQI---------- 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  441 sedsgDGSGHDSLLMLESQIQISGHELFERQQEIGQLRSMCRALQLEMRRS----LATQQLLLQEKAAIEQESSELQDfl 516
Cdd:COG4913   333 -----RGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASaeefAALRAEAAALLEALEEELEALEE-- 405

                         170       180
                  ....*....|....*....|....*..
gi 442630662  517 qhEKAAQCDALRDLEADYQAVKLQLAN 543
Cdd:COG4913   406 --ALAEAEAALRDLRRELRELEAEIAS 430
PHA03247 PHA03247
large tegument protein UL36; Provisional
 92-336 2.20e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 2.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   92 VTTVAQTPSETGSEKTSPPRRTGSVKKkvAMFEPEPTGTPAKDQLRGRVANLkraESLPRNSAAPGTPGTPSTHRDKA-- 169
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPSRLAP--AILPDEPVGEPVHPRMLTWIRGL---EELASDDAGDPPPPLPPAAPPAApd 2565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  170 RLSTSSFRVPSTTGTPSSSRLARPQKPdtlpnalnraqsvqrltqvqrtPSLSRARTPGTPSDDGRWPANRGAARRGMSV 249
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPAVTSRARRPDAP----------------------PQSARPRAPVDDRGDPRGPAPPSPLPPDTHA 2623

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  250 -TPEVTTNRMRGSPAPGG-TLPRRRKQQSVEDLTGGRLSRSNSISRAAivDARMTSSVMVVPTsRRSLAPAAAKVNSLRR 327
Cdd:PHA03247 2624 pDPPPPSPSPAANEPDPHpPPTVPPPERPRDDPAPGRVSRPRRARRLG--RAAQASSPPQRPR-RRAARPTVGSLTSLAD 2700

                         250
                  ....*....|.
gi 442630662  328 P--QPATPRTR 336
Cdd:PHA03247 2701 PppPPPTPEPA 2711
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 364-629 2.36e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 2.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   364 RAVDAVEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELhlnTERVMGMLELARVVSASAGTPTSED 443
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI---ENVKSELKELEARIEELEEDLHKLE 778

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   444 SGDGSGHDSLLMleSQIQISGHELFERQQEIGQLRSMCRALQLEMRRSLATQQLLLQEKAAIEQESSELQDflqhEKAAQ 523
Cdd:TIGR02169  779 EALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE----QIKSI 852

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   524 CDALRDLEADYQAVKLQLANREEEAKVLRDECRHLVRLNEQRRQENRLLQTKFTALENKSRELIHQQNASVAGASTALSG 603
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932

                          250       260
                   ....*....|....*....|....*.
gi 442630662   604 LhSRLDGLVEQLVySYSISEQDLEDI 629
Cdd:TIGR02169  933 L-SEIEDPKGEDE-EIPEEELSLEDV 956
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 98-269 3.06e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 48.24  E-value: 3.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   98 TPSETGSEKTSPPRRTGSVKKKVAMFEPEPTGTPAKDQL-RGRVANL-KRAESLPRNSAAPGTPG-----TPSTHRDKAR 170
Cdd:PHA03307  280 SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSsSSRESSSsSTSSSSESSRGAAVSPGpspsrSPSPSRPPPP 359

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  171 LSTSSfrvPSTTGTPSSSRLARPQKPDTLPNALNRAQSVQRLTQVQRTPSLSRARTPGTPSDDGrwpanrGAARRGMSVT 250
Cdd:PHA03307  360 ADPSS---PRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAG------AASGAFYARY 430

                         170
                  ....*....|....*....
gi 442630662  251 PEVTTNrmrGSPAPGGTLP 269
Cdd:PHA03307  431 PLLTPS---GEPWPGSPPP 446
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 99-295 1.05e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 1.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   99 PSETGSEKTSPPRRTGSVKKKVAMFEPEPTGTPAKDQLRGRVANLKRAESLPRNSAAPGTPGTPSThrdkarlSTSSFRV 178
Cdd:PHA03307  233 GASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSP-------SPSSPGS 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  179 PSTTGTPSSSRLARPQKPDTLPNALnRAQSVQRLTQVQRTPSLSRARTPGTPSD--DGRWPANRGAARRGMSvTPEVTTN 256
Cdd:PHA03307  306 GPAPSSPRASSSSSSSRESSSSSTS-SSSESSRGAAVSPGPSPSRSPSPSRPPPpaDPSSPRKRPRPSRAPS-SPAASAG 383

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 442630662  257 RMRGSPAPGGTLPRRRKQQSVEDLTGGRLSRSNSISRAA 295
Cdd:PHA03307  384 RPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAA 422
PHA03247 PHA03247
large tegument protein UL36; Provisional
 125-333 2.02e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 2.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  125 PEPTGTPAKDQLRGRVANLKRAESLPRNSAAPGTPGTPSTHRDKARLSTSS-----FRVPSTTGTPSS-SRLARPQKPDT 198
Cdd:PHA03247 2627 PPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASsppqrPRRRAARPTVGSlTSLADPPPPPP 2706

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  199 LPNALNRAQSVQrlTQVQRTPSLSRARTPGTPSDDGRWPANRGAARRG---MSVTPEVTTNRMRGSP--APGGTLPRRRK 273
Cdd:PHA03247 2707 TPEPAPHALVSA--TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGgpaRPARPPTTAGPPAPAPpaAPAAGPPRRLT 2784

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  274 QQSVEDLTGGRLSrSNSISRAAIVDARMTSSVMVVPTSRRSLAPAAAKVNSLRRPQPATP 333
Cdd:PHA03247 2785 RPAVASLSESRES-LPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP 2843
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 382-639 3.75e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 3.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   382 QREFELEQLRHEVRQLSGKLQREREEKLAMqQELHLNTERVMGMLELARVVSASAGTPTSEDSGDGsghdsllmLESQIQ 461
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERLRREREKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLAS--------LEEELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   462 ISGHELFERQQEIGQLRSMCRALQLEMRRSLATQQLLLQEK------------AAIEQESSELQDFlqHEKAAQCDALRD 529
Cdd:TIGR02169  255 KLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKigeleaeiasleRSIAEKERELEDA--EERLAKLEAEID 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   530 --------LEADYQAVKLQLANREEEAKVLRDECRHLVRLNEQRRQENRLLQTKFTALENKSRELIHQQNasvagastAL 601
Cdd:TIGR02169  333 kllaeieeLEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN--------EL 404

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 442630662   602 SGLHSRLDGLVEQLVYSYSISEQDLEDIR-----FQAETEHVQ 639
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAGIEakineLEEEKEDKA 447
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 364-579 3.88e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 3.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 364 RAVDAVEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQR--------EREEKLAMQQELHLNTERVMGMLELARVVSAS 435
Cdd:COG4942   34 QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAleqelaalEAELAELEKEIAELRAELEAQKEELAELLRAL 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 436 AGTptsedsgdgSGHDSLLMLESQ---------IQISGHELFERQQEIGQLRSMCRALQlEMRRSLATQQlllQEKAAIE 506
Cdd:COG4942  114 YRL---------GRQPPLALLLSPedfldavrrLQYLKYLAPARREQAEELRADLAELA-ALRAELEAER---AELEALL 180

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442630662 507 QESSELQDFLQHEKAAQCDALRDLEADYQAVKLQLANREEEAKVLRDECRHLVRlnEQRRQENRLLQTKFTAL 579
Cdd:COG4942  181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA--EAAAAAERTPAAGFAAL 251
PHA03247 PHA03247
large tegument protein UL36; Provisional
 124-333 4.40e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 4.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  124 EPEPTG-TPAKDQLRGRVANLKRAESLPRNSAAPGTPGTPSTHRDKARLSTSSFRVPSTTGTPSSSRLARPQKPDTLPNA 202
Cdd:PHA03247 2709 EPAPHAlVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAV 2788

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  203 LNRAQSVQRLTQ-----------VQRTPSLSRARTPGTPSDDgrwPANRGAARRGMSVTPEVTTNRMRGSPAPGGTLPRR 271
Cdd:PHA03247 2789 ASLSESRESLPSpwdpadppaavLAPAAALPPAASPAGPLPP---PTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRR 2865

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442630662  272 -RKQQSVEDLTGGRLSRSNSISRAAIvdARMTSSVMVVPTSRRSLAPAAAKVNSLRRPQPATP 333
Cdd:PHA03247 2866 pPSRSPAAKPAAPARPPVRRLARPAV--SRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPP 2926
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 374-615 5.88e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 5.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 374 QSTQAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELHLNTERvmgMLELARVVSAsagtptsedsgdgsghdsl 453
Cdd:COG4942   16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR---IAALARRIRA------------------- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 454 lmLESQIQISGHELFERQQEIGQLRSMCRALQLEMRRSLATQQLLLQEKAAIEQESSElqDFLQHEKAAQ-----CDALR 528
Cdd:COG4942   74 --LEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPE--DFLDAVRRLQylkylAPARR 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 529 DLEADYQAVKLQLANREEEAKVLRDECRHLVRLNEQRRQENRLLQTKFTALENKsrelIHQQNASVAGASTALSGLHSRL 608
Cdd:COG4942  150 EQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLAR----LEKELAELAAELAELQQEAEEL 225


                 ....*..
gi 442630662 609 DGLVEQL 615
Cdd:COG4942  226 EALIARL 232
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 467-643 8.61e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 8.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   467 LFERQQEIGQLRSMCRALQLEMRRSLATQQLLLQEKAAIEQESSELQDflqhEKAAQCDALRDLEADYQAVKLQLANREE 546
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK----ELEELSRQISALRKDLARLEAEVEQLEE 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   547 EAKVLRDEcrhLVRLNEQRRQENRLLQTKFTALENKSRElIHQQNASVAGASTALSGLHSRLDGLVEQLvysysiseqDL 626
Cdd:TIGR02168  748 RIAQLSKE---LTELEAEIEELEERLEEAEEELAEAEAE-IEELEAQIEQLKEELKALREALDELRAEL---------TL 814

                          170
                   ....*....|....*..
gi 442630662   627 EDIRFQAETEHVQNGQR 643
Cdd:TIGR02168  815 LNEEAANLRERLESLER 831
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 382-570 1.36e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  382 QREFELEQLRHEVRQLsgKLQREREEKLAM-----------QQELHLNTERVMGMLELARVVSasagtptsedsgdgsgh 450
Cdd:pfam17380 345 ERERELERIRQEERKR--ELERIRQEEIAMeisrmrelerlQMERQQKNERVRQELEAARKVK----------------- 405

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  451 dsllMLESqiqisghelfERQQEIGQLRSMCRALQLEMRRSLATQQLLLQEKAAIEQESSELQDFlqhEKAAQCDALRDL 530
Cdd:pfam17380 406 ----ILEE----------ERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQ---ERQQQVERLRQQ 468

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 442630662  531 EADYQAVKLQLANREEEAKVLRDECRHLVrlnEQRRQENR 570
Cdd:pfam17380 469 EEERKRKKLELEKEKRDRKRAEEQRRKIL---EKELEERK 505
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 386-643 1.52e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 1.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 386 ELEQLRHEVRQLSGKLQREREEKLAMQQELhLNTERVMGMLELARvvsasagtptsedsgdgsghdsllmLESQIQISGH 465
Cdd:COG1196  221 ELKELEAELLLLKLRELEAELEELEAELEE-LEAELEELEAELAE-------------------------LEAELEELRL 274

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 466 ELFERQQEIGQLRSMCRALQLEMRRSLATQQLLLQEKAAIEQESSELQDFLQH----------EKAAQCDALRDLEADYQ 535
Cdd:COG1196  275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEleeeleeleeELEELEEELEEAEEELE 354

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 536 AVKLQLANREEEAKVLRDECRHLVRLNEQRRQENRLLQTKFTALENKSRELIHQQNASVAGASTALSGLHSRLDGLVEQL 615
Cdd:COG1196  355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434

                        250       260
                 ....*....|....*....|....*...
gi 442630662 616 VYSYSISEQDLEDIRFQAETEHVQNGQR 643
Cdd:COG1196  435 EEEEEEEEALEEAAEEEAELEEEEEALL 462
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 350-592 2.38e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.85  E-value: 2.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 350 EDLEQVLGGGLLQTRAVDAVEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELhLNTERVMGMLELA 429
Cdd:COG1196  281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL-EEAEEELEEAEAE 359

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 430 RVVSASAgtptsedsgdgsghdsLLMLESQIQisghelfERQQEIGQLRSMCRALQLEMRRSLATQQLLLQEKAAIEQES 509
Cdd:COG1196  360 LAEAEEA----------------LLEAEAELA-------EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 510 SELQDflqhEKAAQCDALRDLEADYQAVKLQLANREEEAKVLRDECRHLVRLNEQRRQENRLLQTKFTALENKSRELIHQ 589
Cdd:COG1196  417 ERLEE----ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492


                 ...
gi 442630662 590 QNA 592
Cdd:COG1196  493 LLL 495
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 348-639 3.41e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.49  E-value: 3.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   348 TSEDLEQVLGGGLLQTRAVDAVEQRNQSTQAEPDQREFELEQLRHEVRQLSG------KLQRERE-----EKLAM----- 411
Cdd:TIGR00618  223 VLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAqeavleETQERINrarkaAPLAAhikav 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   412 ----QQELHLNTERVMGMLELARVVSASAGTptSEDSGDGSGHDSLLmlesQIQISGHELFERQ--QEIGQLRSMCRALQ 485
Cdd:TIGR00618  303 tqieQQAQRIHTELQSKMRSRAKLLMKRAAH--VKQQSSIEEQRRLL----QTLHSQEIHIRDAheVATSIREISCQQHT 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   486 LEMR-RSLATQQLLLQEKAAIEQESSELQDFLQHEKAAQCDALRDLEADYQAVK-----------LQLANREEEAKVLRD 553
Cdd:TIGR00618  377 LTQHiHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKkqqelqqryaeLCAAAITCTAQCEKL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662   554 ECRHLVRLNEQRRQENRLLQTKFTALENKSRE--------LIHQQNASVAGASTA-------LSGLHSRLDGLVEQLVYS 618
Cdd:TIGR00618  457 EKIHLQESAQSLKEREQQLQTKEQIHLQETRKkavvlarlLELQEEPCPLCGSCIhpnparqDIDNPGPLTRRMQRGEQT 536

                          330       340
                   ....*....|....*....|...
gi 442630662   619 YSISEQDLEDIRFQ--AETEHVQ 639
Cdd:TIGR00618  537 YAQLETSEEDVYHQltSERKQRA 559
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
334-638 4.59e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.91  E-value: 4.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 334 RTRIYHETAVQTALTSEDLEQVLgggllqtRAVDAVEQRNQSTQAEPDQREFELEQLRHEVRQLSGKLQREREEK----- 408
Cdd:COG4717  176 QEELEELLEQLSLATEEELQDLA-------EELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlkea 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 409 -------------LAMQQELHLNTERVMGML-ELARVVSASAGTPTSEDSGDGSGHDSLLMLESQIQISGHELFERQQEI 474
Cdd:COG4717  249 rlllliaaallalLGLGGSLLSLILTIAGVLfLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAL 328

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 475 GQLRSMCRALQLEMRRSLATQQLL------LQEKAAIEQESSELQDFLQH----------EKAAQCDALRDLEADYQAVK 538
Cdd:COG4717  329 GLPPDLSPEELLELLDRIEELQELlreaeeLEEELQLEELEQEIAALLAEagvedeeelrAALEQAEEYQELKEELEELE 408

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662 539 LQLANREEEAKVL---RDECRHLVRLNEQRRQENRlLQTKFTALENKSRELIHQQNAsvAGASTALSGLHSRLDGLVEQL 615
Cdd:COG4717  409 EQLEELLGELEELleaLDEEELEEELEELEEELEE-LEEELEELREELAELEAELEQ--LEEDGELAELLQELEELKAEL 485

                        330       340
                 ....*....|....*....|....*....
gi 442630662 616 ------VYSYSISEQDLEDIRFQAETEHV 638
Cdd:COG4717  486 relaeeWAALKLALELLEEAREEYREERL 514
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
387-614 4.94e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 4.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  387 LEQLRHEVRQLSGKLQREREEKLAMQQELHLNTERVMGMLELARVVSASAGTPTSEDSGDG---------SGHDSLLMLE 457
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAEleaelerldASSDDLAALE 691

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  458 SQIQisghelfERQQEIGQLRSMCRALQLEMRRslatqqlLLQEKAAIEQESSELQDFLQhekAAQCDALRDLEADYQAV 537
Cdd:COG4913   692 EQLE-------ELEAELEELEEELDELKGEIGR-------LEKELEQAEEELDELQDRLE---AAEDLARLELRALLEER 754

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630662  538 KLQLANREEEAKVLRdecrhlvRLNEQRRQENRLLQTKFTALENKSRELIHQQNASVAGASTALSGLHS---RLDGLVEQ 614
Cdd:COG4913   755 FAAALGDAVERELRE-------NLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEylaLLDRLEED 827
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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