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Conserved domains on  [gi|442628053|ref|NP_001260504|]
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miles to go, isoform H [Drosophila melanogaster]

Protein Classification

fibronectin type III domain-containing protein( domain architecture ID 10045852)

fibronectin type III (FN3) domain-containing protein may be involved in specific interactions with other molecules through its FN3 domain

CATH:  2.60.40.10
Gene Ontology:  GO:0005515
PubMed:  19576999|9837732|8981327

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1095-1324 4.11e-24

Fibronectin type 3 domain [General function prediction only];


:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 109.71  E-value: 4.11e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1095 DLTPGGMYETQVRAINRIGAGSWSQWMRFTAAAAAPGVPEELRVLVKSATHLGVSWQPPlqeNGAPVTSYTLksasqERK 1174
Cdd:COG3401   198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPV---TESDATGYRV-----YRS 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1175 EDDSE--EEVKEPPSSEFHNcyqgpqtcaelRNLSPYTRYHFRIQASNSAGT-GNSSDVISVCTPAAVPGAPQ-MQGYEF 1250
Cdd:COG3401   270 NSGDGpfTKVATVTTTSYTD-----------TGLTNGTTYYYRVTAVDAAGNeSAPSNVVSVTTDLTPPAAPSgLTATAV 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1251 TAQEVTLNWTqpAAHGSPICSYNIEYGE------RTIATPDACTRYTVSGLMPETGYKFRVQAVNAIG-AGAFSAYAKLT 1323
Cdd:COG3401   339 GSSSITLSWT--ASSDADVTGYNVYRSTsgggtyTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSAT 416


                  .
gi 442628053 1324 T 1324
Cdd:COG3401   417 T 417
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 752-839 1.80e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 70.60  E-value: 1.80e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  752 KLVSRTKNSINLRWAAPAANGASIQHYLLEYDEgrMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPY 831
Cdd:cd00063     8 RVTDVTSTSVTLSWTPPEDDGGPITGYVVEYRE--KGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPP 85


                  ....*...
gi 442628053  832 SPVASYST 839
Cdd:cd00063    86 SESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1334-1429 4.79e-08

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 52.11  E-value: 4.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1334 LECSGAGHNYIKLKWgengngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAV--YSGTNCMCKVHKLQERSSYTFRIYA 1411
Cdd:cd00063     7 LRVTDVTSTSVTLSW----------TPPEDDGGPITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRA 76

                          90
                  ....*....|....*...
gi 442628053 1412 HTDrAGDGDYSEEFVFET 1429
Cdd:cd00063    77 VNG-GGESPPSESVTVTT 93
FN3 super family cl27307
Fibronectin type 3 domain [General function prediction only];
652-840 2.41e-07

Fibronectin type 3 domain [General function prediction only];


The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 55.78  E-value: 2.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  652 VIDVTSRAAKIIWeSPAIANTVTvdmrqlRYQVLLCDSGKQcKYKSLYQGEAYECIVQDLQPGQDYLVRLQVHYQklTGT 731
Cdd:COG3401   241 ATADTPGSVTLSW-DPVTESDAT------GYRVYRSNSGDG-PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDA--AGN 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  732 VSDPTEF---RTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASiqHYLLEYDEGrmpgQPQKFVELAK-IKAKHYVI 807
Cdd:COG3401   311 ESAPSNVvsvTTDLTPPAAPSGLTATAVGSSSITLSWTASSDADVT--GYNVYRSTS----GGGTYTKIAEtVTTTSYTD 384

                         170       180       190
                  ....*....|....*....|....*....|....
gi 442628053  808 GKLQPTTVYSFRLAAVNEAG-QSPYSPVASYSTS 840
Cdd:COG3401   385 TGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTA 418
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 936-1027 3.18e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 49.80  E-value: 3.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  936 PGRPGKPHAKGkIHGTQFKARWDAPSDSGGaEILCYHLELSAAGPAFERIYS---GAETEAMCERLQPGTTYALRACCEG 1012
Cdd:cd00063     1 PSPPTNLRVTD-VTSTSVTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVEvtpGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|....*
gi 442628053 1013 PAGQSPYSDIGHVTT 1027
Cdd:cd00063    79 GGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1049-1124 1.95e-05

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 44.79  E-value: 1.95e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442628053 1049 ALLKLRPPEYNGGaPILEFEAQMRRLEQVQPPQL-VYRGKQTYFVAQDLTPGGMYETQVRAINRIGAGSWSQWMRFT 1124
Cdd:cd00063    17 VTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVeVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVT 92
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 864-931 4.54e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.54e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628053  864 WERRAQDG----DFLLQLQDAETGHGF-LNTYKGTELQTECLQLRRASSYQFRLRSENEAGFSPWSPEVSYRT 931
Cdd:cd00063    21 WTPPEDDGgpitGYVVEYREKGSGDWKeVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
 
Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1095-1324 4.11e-24

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 109.71  E-value: 4.11e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1095 DLTPGGMYETQVRAINRIGAGSWSQWMRFTAAAAAPGVPEELRVLVKSATHLGVSWQPPlqeNGAPVTSYTLksasqERK 1174
Cdd:COG3401   198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPV---TESDATGYRV-----YRS 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1175 EDDSE--EEVKEPPSSEFHNcyqgpqtcaelRNLSPYTRYHFRIQASNSAGT-GNSSDVISVCTPAAVPGAPQ-MQGYEF 1250
Cdd:COG3401   270 NSGDGpfTKVATVTTTSYTD-----------TGLTNGTTYYYRVTAVDAAGNeSAPSNVVSVTTDLTPPAAPSgLTATAV 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1251 TAQEVTLNWTqpAAHGSPICSYNIEYGE------RTIATPDACTRYTVSGLMPETGYKFRVQAVNAIG-AGAFSAYAKLT 1323
Cdd:COG3401   339 GSSSITLSWT--ASSDADVTGYNVYRSTsgggtyTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSAT 416


                  .
gi 442628053 1324 T 1324
Cdd:COG3401   417 T 417
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1130-1235 5.51e-16

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 74.84  E-value: 5.51e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1130 PGVPEELRVLVKSATHLGVSWQPPlQENGAPVTSYTLksasqERKEDDSEEEVKEPPSSefhncyqGPQTCAELRNLSPY 1209
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPP-EDDGGPITGYVV-----EYREKGSGDWKEVEVTP-------GSETSYTLTGLKPG 67

                          90       100
                  ....*....|....*....|....*.
gi 442628053 1210 TRYHFRIQASNSAGTGNSSDVISVCT 1235
Cdd:cd00063    68 TEYEFRVRAVNGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 752-839 1.80e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 70.60  E-value: 1.80e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  752 KLVSRTKNSINLRWAAPAANGASIQHYLLEYDEgrMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPY 831
Cdd:cd00063     8 RVTDVTSTSVTLSWTPPEDDGGPITGYVVEYRE--KGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPP 85


                  ....*...
gi 442628053  832 SPVASYST 839
Cdd:cd00063    86 SESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1130-1225 4.17e-12

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 63.40  E-value: 4.17e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053   1130 PGVPEELRVLVKSATHLGVSWQPPLQENG-APVTSYTLksasQERKEDDSEEEVKEPPSsefhncyqgpQTCAELRNLSP 1208
Cdd:smart00060    1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGItGYIVGYRV----EYREEGSEWKEVNVTPS----------STSYTLTGLKP 66

                            90
                    ....*....|....*..
gi 442628053   1209 YTRYHFRIQASNSAGTG 1225
Cdd:smart00060   67 GTEYEFRVRAVNGAGEG 83
fn3 pfam00041
Fibronectin type III domain;
1133-1228 8.01e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 8.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  1133 PEELRVLVKSATHLGVSWQPPLQENGaPVTSYTLksasqERKEDDSEEEVKEPPSSefhncyqGPQTCAELRNLSPYTRY 1212
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPPDGNG-PITGYEV-----EYRPKNSGEPWNEITVP-------GTTTSVTLTGLKPGTEY 69

                           90
                   ....*....|....*.
gi 442628053  1213 HFRIQASNSAGTGNSS 1228
Cdd:pfam00041   70 EVRVQAVNGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 752-829 1.64e-09

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 56.08  E-value: 1.64e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628053    752 KLVSRTKNSINLRWAAPAANGasIQHYLLEYDEGRMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQS 829
Cdd:smart00060    8 RVTDVTSTSVTLSWEPPPDDG--ITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
fn3 pfam00041
Fibronectin type III domain;
752-832 9.85e-09

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 53.96  E-value: 9.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053   752 KLVSRTKNSINLRWAAPAANGASIQHYLLEYDEGRMPGQPQKFVELAkiKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPY 831
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPG--TTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84


                   .
gi 442628053   832 S 832
Cdd:pfam00041   85 S 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1334-1429 4.79e-08

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 52.11  E-value: 4.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1334 LECSGAGHNYIKLKWgengngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAV--YSGTNCMCKVHKLQERSSYTFRIYA 1411
Cdd:cd00063     7 LRVTDVTSTSVTLSW----------TPPEDDGGPITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRA 76

                          90
                  ....*....|....*...
gi 442628053 1412 HTDrAGDGDYSEEFVFET 1429
Cdd:cd00063    77 VNG-GGESPPSESVTVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
710-836 1.43e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 56.55  E-value: 1.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  710 DLQPGQDYLVRLQVHYQKLTGTVSDPTEFRTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASiqHYLLEydegRMPG 789
Cdd:COG3401   198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPVTESDAT--GYRVY----RSNS 271

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 442628053  790 QPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAG-QSPYSPVAS 836
Cdd:COG3401   272 GDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVS 319
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
652-840 2.41e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 55.78  E-value: 2.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  652 VIDVTSRAAKIIWeSPAIANTVTvdmrqlRYQVLLCDSGKQcKYKSLYQGEAYECIVQDLQPGQDYLVRLQVHYQklTGT 731
Cdd:COG3401   241 ATADTPGSVTLSW-DPVTESDAT------GYRVYRSNSGDG-PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDA--AGN 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  732 VSDPTEF---RTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASiqHYLLEYDEGrmpgQPQKFVELAK-IKAKHYVI 807
Cdd:COG3401   311 ESAPSNVvsvTTDLTPPAAPSGLTATAVGSSSITLSWTASSDADVT--GYNVYRSTS----GGGTYTKIAEtVTTTSYTD 384

                         170       180       190
                  ....*....|....*....|....*....|....
gi 442628053  808 GKLQPTTVYSFRLAAVNEAG-QSPYSPVASYSTS 840
Cdd:COG3401   385 TGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTA 418
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 936-1027 3.18e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 49.80  E-value: 3.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  936 PGRPGKPHAKGkIHGTQFKARWDAPSDSGGaEILCYHLELSAAGPAFERIYS---GAETEAMCERLQPGTTYALRACCEG 1012
Cdd:cd00063     1 PSPPTNLRVTD-VTSTSVTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVEvtpGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|....*
gi 442628053 1013 PAGQSPYSDIGHVTT 1027
Cdd:cd00063    79 GGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 645-740 1.84e-06

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.88  E-value: 1.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  645 SAIEKPEVIDVTSRAAKIIWESPAIANTvtvdmRQLRYQVLLCDSG----KQCKYKSlyqGEAYECIVQDLQPGQDYLVR 720
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEDDGG-----PITGYVVEYREKGsgdwKEVEVTP---GSETSYTLTGLKPGTEYEFR 73

                          90       100
                  ....*....|....*....|
gi 442628053  721 LQVHYQKLTGTVSDPTEFRT 740
Cdd:cd00063    74 VRAVNGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1049-1124 1.95e-05

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 44.79  E-value: 1.95e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442628053 1049 ALLKLRPPEYNGGaPILEFEAQMRRLEQVQPPQL-VYRGKQTYFVAQDLTPGGMYETQVRAINRIGAGSWSQWMRFT 1124
Cdd:cd00063    17 VTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVeVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVT 92
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 936-1017 2.74e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.45  E-value: 2.74e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053    936 PGRPGKPHAKGkIHGTQFKARWDAPSDSGG-AEILCYHLELSAAGPAFERIY-SGAETEAMCERLQPGTTYALRACCEGP 1013
Cdd:smart00060    1 PSPPSNLRVTD-VTSTSVTLSWEPPPDDGItGYIVGYRVEYREEGSEWKEVNvTPSSTSYTLTGLKPGTEYEFRVRAVNG 79


                    ....
gi 442628053   1014 AGQS 1017
Cdd:smart00060   80 AGEG 83
fn3 pfam00041
Fibronectin type III domain;
645-730 1.17e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 39.71  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053   645 SAIEKPEVIDVTSRAAKIIWESPAIANtVTVDMRQLRYQVllCDSGKQCKYKSLyQGEAYECIVQDLQPGQDYLVRLQVH 724
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPDGN-GPITGYEVEYRP--KNSGEPWNEITV-PGTTTSVTLTGLKPGTEYEVRVQAV 76


                   ....*.
gi 442628053   725 YQKLTG 730
Cdd:pfam00041   77 NGGGEG 82
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1054-1115 3.67e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.98  E-value: 3.67e-03
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442628053   1054 RPPEYNGGAPILEFEAQMRRLEQVQPpQLVYRGKQTYFVAQDLTPGGMYETQVRAINRIGAG 1115
Cdd:smart00060   23 PPPDDGITGYIVGYRVEYREEGSEWK-EVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
fn3 pfam00041
Fibronectin type III domain;
1333-1422 3.71e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 38.16  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  1333 RLECSGAGHNYIKLKWgengngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAVY--SGTNCMCKVHKLQERSSYTFRIY 1410
Cdd:pfam00041    5 NLTVTDVTSTSLTVSW----------TPPPDGNGPITGYEVEYRPKNSGEPWNEItvPGTTTSVTLTGLKPGTEYEVRVQ 74

                           90
                   ....*....|..
gi 442628053  1411 AHTDrAGDGDYS 1422
Cdd:pfam00041   75 AVNG-GGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 645-727 3.78e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.98  E-value: 3.78e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053    645 SAIEKPEVIDVTSRAAKIIWESPAIANTVTvdmRQLRYQVLLCDSGKQCKyKSLYQGEAYECIVQDLQPGQDYLVRLQVH 724
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDGITG---YIVGYRVEYREEGSEWK-EVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77


                    ...
gi 442628053    725 YQK 727
Cdd:smart00060   78 NGA 80
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 864-931 4.54e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.54e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628053  864 WERRAQDG----DFLLQLQDAETGHGF-LNTYKGTELQTECLQLRRASSYQFRLRSENEAGFSPWSPEVSYRT 931
Cdd:cd00063    21 WTPPEDDGgpitGYVVEYREKGSGDWKeVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1333-1419 7.08e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.21  E-value: 7.08e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053   1333 RLECSGAGHNYIKLKWGEngngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAVYSGTNCMCKVHKLQERSSYTFRIYAH 1412
Cdd:smart00060    6 NLRVTDVTSTSVTLSWEP--------PPDDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77


                    ....*..
gi 442628053   1413 TDrAGDG 1419
Cdd:smart00060   78 NG-AGEG 83
 
Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1095-1324 4.11e-24

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 109.71  E-value: 4.11e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1095 DLTPGGMYETQVRAINRIGAGSWSQWMRFTAAAAAPGVPEELRVLVKSATHLGVSWQPPlqeNGAPVTSYTLksasqERK 1174
Cdd:COG3401   198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPV---TESDATGYRV-----YRS 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1175 EDDSE--EEVKEPPSSEFHNcyqgpqtcaelRNLSPYTRYHFRIQASNSAGT-GNSSDVISVCTPAAVPGAPQ-MQGYEF 1250
Cdd:COG3401   270 NSGDGpfTKVATVTTTSYTD-----------TGLTNGTTYYYRVTAVDAAGNeSAPSNVVSVTTDLTPPAAPSgLTATAV 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1251 TAQEVTLNWTqpAAHGSPICSYNIEYGE------RTIATPDACTRYTVSGLMPETGYKFRVQAVNAIG-AGAFSAYAKLT 1323
Cdd:COG3401   339 GSSSITLSWT--ASSDADVTGYNVYRSTsgggtyTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSAT 416


                  .
gi 442628053 1324 T 1324
Cdd:COG3401   417 T 417
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1130-1235 5.51e-16

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 74.84  E-value: 5.51e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1130 PGVPEELRVLVKSATHLGVSWQPPlQENGAPVTSYTLksasqERKEDDSEEEVKEPPSSefhncyqGPQTCAELRNLSPY 1209
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPP-EDDGGPITGYVV-----EYREKGSGDWKEVEVTP-------GSETSYTLTGLKPG 67

                          90       100
                  ....*....|....*....|....*.
gi 442628053 1210 TRYHFRIQASNSAGTGNSSDVISVCT 1235
Cdd:cd00063    68 TEYEFRVRAVNGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 752-839 1.80e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 70.60  E-value: 1.80e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  752 KLVSRTKNSINLRWAAPAANGASIQHYLLEYDEgrMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPY 831
Cdd:cd00063     8 RVTDVTSTSVTLSWTPPEDDGGPITGYVVEYRE--KGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPP 85


                  ....*...
gi 442628053  832 SPVASYST 839
Cdd:cd00063    86 SESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1240-1324 5.51e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 69.06  E-value: 5.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1240 PGAPQ-MQGYEFTAQEVTLNWTQPAAHGSPICSYNIEYGERTIATPDAC-------TRYTVSGLMPETGYKFRVQAVNAI 1311
Cdd:cd00063     1 PSPPTnLRVTDVTSTSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVevtpgseTSYTLTGLKPGTEYEFRVRAVNGG 80

                          90
                  ....*....|...
gi 442628053 1312 GAGAFSAYAKLTT 1324
Cdd:cd00063    81 GESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1130-1225 4.17e-12

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 63.40  E-value: 4.17e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053   1130 PGVPEELRVLVKSATHLGVSWQPPLQENG-APVTSYTLksasQERKEDDSEEEVKEPPSsefhncyqgpQTCAELRNLSP 1208
Cdd:smart00060    1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGItGYIVGYRV----EYREEGSEWKEVNVTPS----------STSYTLTGLKP 66

                            90
                    ....*....|....*..
gi 442628053   1209 YTRYHFRIQASNSAGTG 1225
Cdd:smart00060   67 GTEYEFRVRAVNGAGEG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1240-1314 5.17e-12

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 63.40  E-value: 5.17e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053   1240 PGAPQ-MQGYEFTAQEVTLNWTQPA--AHGSPICSYNIEYGE-----RTIATPDACTRYTVSGLMPETGYKFRVQAVNAI 1311
Cdd:smart00060    1 PSPPSnLRVTDVTSTSVTLSWEPPPddGITGYIVGYRVEYREegsewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 442628053   1312 GAG 1314
Cdd:smart00060   81 GEG 83
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1072-1320 7.03e-12

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 70.42  E-value: 7.03e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1072 RRLEQVQPPQLVYRGKQTYFVAQDLTPGGMYETQVRAINRIGAGS-WSQWMRFTAAAAAPGVPEELRVLVKSATHLGVSW 1150
Cdd:COG3401   268 RSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGNESaPSNVVSVTTDLTPPAAPSGLTATAVGSSSITLSW 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1151 QPPLqenGAPVTSYTLksasqERKE--DDSEEEVKEPPSSEFHncyqgpqtcaELRNLSPYTRYHFRIQASNSAGT-GNS 1227
Cdd:COG3401   348 TASS---DADVTGYNV-----YRSTsgGGTYTKIAETVTTTSY----------TDTGLTPGTTYYYKVTAVDAAGNeSAP 409

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1228 SDVISVCTPAAVPGAPQMQGYEFTAQEVTLNWTQPAAHGSPICSYNIEY---GERTIATPDACTRYTV-SGLMPETGYKF 1303
Cdd:COG3401   410 SEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLadgGDTGNAVPFTTTSSTVtATTTDTTTANL 489

                         250
                  ....*....|....*..
gi 442628053 1304 RVQAVNAIGAGAFSAYA 1320
Cdd:COG3401   490 SVTTGSLVGGSGASSVT 506
fn3 pfam00041
Fibronectin type III domain;
1133-1228 8.01e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 8.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  1133 PEELRVLVKSATHLGVSWQPPLQENGaPVTSYTLksasqERKEDDSEEEVKEPPSSefhncyqGPQTCAELRNLSPYTRY 1212
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPPDGNG-PITGYEV-----EYRPKNSGEPWNEITVP-------GTTTSVTLTGLKPGTEY 69

                           90
                   ....*....|....*.
gi 442628053  1213 HFRIQASNSAGTGNSS 1228
Cdd:pfam00041   70 EVRVQAVNGGGEGPPS 85
fn3 pfam00041
Fibronectin type III domain;
1254-1317 9.36e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.43  E-value: 9.36e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442628053  1254 EVTLNWTQPAAHGSPICSYNIEY-------GERTIATPDACTRYTVSGLMPETGYKFRVQAVNAIGAGAFS 1317
Cdd:pfam00041   15 SLTVSWTPPPDGNGPITGYEVEYrpknsgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 752-829 1.64e-09

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 56.08  E-value: 1.64e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442628053    752 KLVSRTKNSINLRWAAPAANGasIQHYLLEYDEGRMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQS 829
Cdd:smart00060    8 RVTDVTSTSVTLSWEPPPDDG--ITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
fn3 pfam00041
Fibronectin type III domain;
752-832 9.85e-09

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 53.96  E-value: 9.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053   752 KLVSRTKNSINLRWAAPAANGASIQHYLLEYDEGRMPGQPQKFVELAkiKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPY 831
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPG--TTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84


                   .
gi 442628053   832 S 832
Cdd:pfam00041   85 S 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1334-1429 4.79e-08

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 52.11  E-value: 4.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1334 LECSGAGHNYIKLKWgengngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAV--YSGTNCMCKVHKLQERSSYTFRIYA 1411
Cdd:cd00063     7 LRVTDVTSTSVTLSW----------TPPEDDGGPITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRA 76

                          90
                  ....*....|....*...
gi 442628053 1412 HTDrAGDGDYSEEFVFET 1429
Cdd:cd00063    77 VNG-GGESPPSESVTVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
710-836 1.43e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 56.55  E-value: 1.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  710 DLQPGQDYLVRLQVHYQKLTGTVSDPTEFRTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASiqHYLLEydegRMPG 789
Cdd:COG3401   198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPVTESDAT--GYRVY----RSNS 271

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 442628053  790 QPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAG-QSPYSPVAS 836
Cdd:COG3401   272 GDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVS 319
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
652-840 2.41e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 55.78  E-value: 2.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  652 VIDVTSRAAKIIWeSPAIANTVTvdmrqlRYQVLLCDSGKQcKYKSLYQGEAYECIVQDLQPGQDYLVRLQVHYQklTGT 731
Cdd:COG3401   241 ATADTPGSVTLSW-DPVTESDAT------GYRVYRSNSGDG-PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDA--AGN 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  732 VSDPTEF---RTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASiqHYLLEYDEGrmpgQPQKFVELAK-IKAKHYVI 807
Cdd:COG3401   311 ESAPSNVvsvTTDLTPPAAPSGLTATAVGSSSITLSWTASSDADVT--GYNVYRSTS----GGGTYTKIAEtVTTTSYTD 384

                         170       180       190
                  ....*....|....*....|....*....|....
gi 442628053  808 GKLQPTTVYSFRLAAVNEAG-QSPYSPVASYSTS 840
Cdd:COG3401   385 TGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTA 418
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 936-1027 3.18e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 49.80  E-value: 3.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  936 PGRPGKPHAKGkIHGTQFKARWDAPSDSGGaEILCYHLELSAAGPAFERIYS---GAETEAMCERLQPGTTYALRACCEG 1012
Cdd:cd00063     1 PSPPTNLRVTD-VTSTSVTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVEvtpGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|....*
gi 442628053 1013 PAGQSPYSDIGHVTT 1027
Cdd:cd00063    79 GGGESPPSESVTVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1205-1567 8.38e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 53.85  E-value: 8.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1205 NLSPYTRYHFRIQASNSAGTGNSSDVISVCTPAAVPGAPQ-MQGYEFTAQEVTLNWTqpAAHGSPICSYNIEYGE----- 1278
Cdd:COG3401   198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTgLTATADTPGSVTLSWD--PVTESDATGYRVYRSNsgdgp 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1279 -RTIATPDAcTRYTVSGLMPETGYKFRVQAVNAIG-AGAFSAYAKLTTQPAPPAPPR-LECSGAGHNYIKLKWgengngk 1355
Cdd:COG3401   276 fTKVATVTT-TSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPPAAPSgLTATAVGSSSITLSW------- 347

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1356 vvnsNPSGnGGDFTKYfvemyvarakqfqavysgtncmckvhklqerssytfRIYahtdRAGDGDYSEEFVFETSATlpa 1435
Cdd:COG3401   348 ----TASS-DADVTGY------------------------------------NVY----RSTSGGGTYTKIAETVTT--- 379

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1436 nikpprvvqegsvclmelpgqlgmqltlewqhsknsfndrveyelqyavlgaaelegeslspkgrsssssgssngapinl 1515
Cdd:COG3401       --------------------------------------------------------------------------------

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442628053 1516 pnhdyrqlyrgpeTKFTIDNLAAGTCYQFRVcpvrIAAGGELLYGQPSSPLR 1567
Cdd:COG3401   380 -------------TSYTDTGLTPGTTYYYKV----TAVDAAGNESAPSEEVS 414
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 645-740 1.84e-06

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.88  E-value: 1.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  645 SAIEKPEVIDVTSRAAKIIWESPAIANTvtvdmRQLRYQVLLCDSG----KQCKYKSlyqGEAYECIVQDLQPGQDYLVR 720
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEDDGG-----PITGYVVEYREKGsgdwKEVEVTP---GSETSYTLTGLKPGTEYEFR 73

                          90       100
                  ....*....|....*....|
gi 442628053  721 LQVHYQKLTGTVSDPTEFRT 740
Cdd:cd00063    74 VRAVNGGGESPPSESVTVTT 93
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
1148-1324 3.53e-06

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 52.25  E-value: 3.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1148 VSWQPPlqengAPVTSYTLksasQERKEDDS--EEEVKEPPSSEFHNCYQGpqtcaelrnlspytRYHFRIQASNSAGTG 1225
Cdd:COG4733   556 VSWDAP-----AGAVAYEV----EWRRDDGNwvSVPRTSGTSFEVPGIYAG--------------DYEVRVRAINALGVS 612

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1226 nSSDVISVCTP----AAVPGAPQmqgyEFTAQ----EVTLNWTQPAahGSPICSYNIEYGERT-------IATPDACTRY 1290
Cdd:COG4733   613 -SAWAASSETTvtgkTAPPPAPT----GLTATgglgGITLSWSFPV--DADTLRTEIRYSTTGdwasatvAQALYPGNTY 685

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 442628053 1291 TVSGLMPETGYKFRVQAVNAIG-AGAFSAYAKLTT 1324
Cdd:COG4733   686 TLAGLKAGQTYYYRARAVDRSGnVSAWWVSGQASA 720
Pur_ac_phosph_N pfam16656
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple ...
 1133-1235 1.46e-05

Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple acid phosphatase proteins.


Pssm-ID: 465220 [Multi-domain]  Cd Length: 93  Bit Score: 45.09  E-value: 1.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  1133 PEELRV-LVKSATHLGVSWQPPLQENGaPVTSYTLKSASQERKEDDSEEEVKEPpssefhNCYQGPQTCAELRNLSPYTR 1211
Cdd:pfam16656    1 PEQVHLsLTGDSTSMTVSWVTPSAVTS-PVVQYGTSSSALTSTATATSSTYTTG------DGGTGYIHRATLTGLEPGTT 73

                           90       100
                   ....*....|....*....|....
gi 442628053  1212 YHFRIQASNSagtgNSSDVISVCT 1235
Cdd:pfam16656   74 YYYRVGDDNG----GWSEVYSFTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1049-1124 1.95e-05

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 44.79  E-value: 1.95e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442628053 1049 ALLKLRPPEYNGGaPILEFEAQMRRLEQVQPPQL-VYRGKQTYFVAQDLTPGGMYETQVRAINRIGAGSWSQWMRFT 1124
Cdd:cd00063    17 VTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVeVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVT 92
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 936-1017 2.74e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.45  E-value: 2.74e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053    936 PGRPGKPHAKGkIHGTQFKARWDAPSDSGG-AEILCYHLELSAAGPAFERIY-SGAETEAMCERLQPGTTYALRACCEGP 1013
Cdd:smart00060    1 PSPPSNLRVTD-VTSTSVTLSWEPPPDDGItGYIVGYRVEYREEGSEWKEVNvTPSSTSYTLTGLKPGTEYEFRVRAVNG 79


                    ....
gi 442628053   1014 AGQS 1017
Cdd:smart00060   80 AGEG 83
COG3979 COG3979
Chitodextrinase [Carbohydrate transport and metabolism];
1251-1312 6.20e-04

Chitodextrinase [Carbohydrate transport and metabolism];


Pssm-ID: 443178 [Multi-domain]  Cd Length: 369  Bit Score: 44.38  E-value: 6.20e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442628053 1251 TAQEVTLNWTqPAAHGSPICSYNIEYGERTIATPDACTRYTVSGLMPETGYKFRVQAVNAIG 1312
Cdd:COG3979    15 TSSSVSLSWD-ASTDNVGVTGYDVYRGGDQVATVTGLTAWTVTGLTPGTEYTFTVGACDAAG 75
fn3 pfam00041
Fibronectin type III domain;
645-730 1.17e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 39.71  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053   645 SAIEKPEVIDVTSRAAKIIWESPAIANtVTVDMRQLRYQVllCDSGKQCKYKSLyQGEAYECIVQDLQPGQDYLVRLQVH 724
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPDGN-GPITGYEVEYRP--KNSGEPWNEITV-PGTTTSVTLTGLKPGTEYEVRVQAV 76


                   ....*.
gi 442628053   725 YQKLTG 730
Cdd:pfam00041   77 NGGGEG 82
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1054-1115 3.67e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.98  E-value: 3.67e-03
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442628053   1054 RPPEYNGGAPILEFEAQMRRLEQVQPpQLVYRGKQTYFVAQDLTPGGMYETQVRAINRIGAG 1115
Cdd:smart00060   23 PPPDDGITGYIVGYRVEYREEGSEWK-EVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
fn3 pfam00041
Fibronectin type III domain;
1333-1422 3.71e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 38.16  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  1333 RLECSGAGHNYIKLKWgengngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAVY--SGTNCMCKVHKLQERSSYTFRIY 1410
Cdd:pfam00041    5 NLTVTDVTSTSLTVSW----------TPPPDGNGPITGYEVEYRPKNSGEPWNEItvPGTTTSVTLTGLKPGTEYEVRVQ 74

                           90
                   ....*....|..
gi 442628053  1411 AHTDrAGDGDYS 1422
Cdd:pfam00041   75 AVNG-GGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 645-727 3.78e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.98  E-value: 3.78e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053    645 SAIEKPEVIDVTSRAAKIIWESPAIANTVTvdmRQLRYQVLLCDSGKQCKyKSLYQGEAYECIVQDLQPGQDYLVRLQVH 724
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDGITG---YIVGYRVEYREEGSEWK-EVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77


                    ...
gi 442628053    725 YQK 727
Cdd:smart00060   78 NGA 80
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 864-931 4.54e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.54e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442628053  864 WERRAQDG----DFLLQLQDAETGHGF-LNTYKGTELQTECLQLRRASSYQFRLRSENEAGFSPWSPEVSYRT 931
Cdd:cd00063    21 WTPPEDDGgpitGYVVEYREKGSGDWKeVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1333-1419 7.08e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.21  E-value: 7.08e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053   1333 RLECSGAGHNYIKLKWGEngngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAVYSGTNCMCKVHKLQERSSYTFRIYAH 1412
Cdd:smart00060    6 NLRVTDVTSTSVTLSWEP--------PPDDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77


                    ....*..
gi 442628053   1413 TDrAGDG 1419
Cdd:smart00060   78 NG-AGEG 83
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
951-1189 7.23e-03

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 41.47  E-value: 7.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053  951 TQFKARWDAPSDSGGaeilcYHLELSAAGPAFERIYSGAETEAMCERLQPGTtYALRACCEGPAG-QSPYSDIGHVTTEA 1029
Cdd:COG4733   552 TTLTVSWDAPAGAVA-----YEVEWRRDDGNWVSVPRTSGTSFEVPGIYAGD-YEVRVRAINALGvSSAWAASSETTVTG 625

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1030 VPPSAPPPPHCSDPPSPYAALLKLRPPEyngGAPILEFEaqMRRLEQV---QPPQLVYRGKQTYFVAQDLTPGGMYETQV 1106
Cdd:COG4733   626 KTAPPPAPTGLTATGGLGGITLSWSFPV---DADTLRTE--IRYSTTGdwaSATVAQALYPGNTYTLAGLKAGQTYYYRA 700

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442628053 1107 RAINRIG-AGSWsqWMRFTAAAAAPGVPEELRVLVKsATHLGvswqPPLQENGAPVTSYTLKSASQERKEDDSEEEVKEP 1185
Cdd:COG4733   701 RAVDRSGnVSAW--WVSGQASADAAGILDAITGQIL-ETELG----QELDAIIQNATVAEVVAATVTDVTAQIDTAVLFA 773


                  ....
gi 442628053 1186 PSSE 1189
Cdd:COG4733   774 GVAT 777
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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