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Conserved domains on  [gi|442626161|ref|NP_001260092|]
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ninein, isoform F [Drosophila melanogaster]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
271-740 7.11e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.42  E-value: 7.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  271 EEEEVNLQQLTKALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAyRQQHEENLKLRADNKAANQRVALLAVEVDER 350
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE-LAEAEEALLEAEAELAEAEEELEELAEELLE 390
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  351 HASLEDNSKKQVQQLEQRHASMVREITLRMTNDRDhwtsmtgkLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAH 430
Cdd:COG1196   391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEE--------LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  431 IQITELLEQNIKLNQELAQTSSSIGGtpehspLRPRRHSEDKEEEMLQLMEKLAALQMENAQLRDKTDELTIEI------ 504
Cdd:COG1196   463 ELLAELLEEAALLEAALAELLEELAE------AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaay 536
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  505 --------ESLNVELIRSKTKAKKQEKQEKQEDQESAAT------ATKRRGDSPSKTHLTEESPRLGKQRKCTEGEQSDA 570
Cdd:COG1196   537 eaaleaalAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpldkIRARAALAAALARGAIGAAVDLVASDLREADARYY 616
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  571 SNSGDWLALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETSLEQMQRAyedcEDYWQTKLSEE 650
Cdd:COG1196   617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL----EELAERLAEEE 692
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  651 RQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQfskDGRLSPIDERDMLEQQYSELEAEAAQLRSSSIQMLEEKAQEI 730
Cdd:COG1196   693 LELEEALLAEEEEERELAEAEEERLEEELEEEALE---EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
                         490
                  ....*....|
gi 442626161  731 SSLQSEIEDL 740
Cdd:COG1196   770 ERLEREIEAL 779
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
271-740 7.11e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.42  E-value: 7.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  271 EEEEVNLQQLTKALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAyRQQHEENLKLRADNKAANQRVALLAVEVDER 350
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE-LAEAEEALLEAEAELAEAEEELEELAEELLE 390
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  351 HASLEDNSKKQVQQLEQRHASMVREITLRMTNDRDhwtsmtgkLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAH 430
Cdd:COG1196   391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEE--------LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  431 IQITELLEQNIKLNQELAQTSSSIGGtpehspLRPRRHSEDKEEEMLQLMEKLAALQMENAQLRDKTDELTIEI------ 504
Cdd:COG1196   463 ELLAELLEEAALLEAALAELLEELAE------AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaay 536
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  505 --------ESLNVELIRSKTKAKKQEKQEKQEDQESAAT------ATKRRGDSPSKTHLTEESPRLGKQRKCTEGEQSDA 570
Cdd:COG1196   537 eaaleaalAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpldkIRARAALAAALARGAIGAAVDLVASDLREADARYY 616
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  571 SNSGDWLALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETSLEQMQRAyedcEDYWQTKLSEE 650
Cdd:COG1196   617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL----EELAERLAEEE 692
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  651 RQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQfskDGRLSPIDERDMLEQQYSELEAEAAQLRSSSIQMLEEKAQEI 730
Cdd:COG1196   693 LELEEALLAEEEEERELAEAEEERLEEELEEEALE---EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
                         490
                  ....*....|
gi 442626161  731 SSLQSEIEDL 740
Cdd:COG1196   770 ERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
393-730 1.65e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 1.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   393 KLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQE---LAQTSSSIGGTPEHSPLRPRRHS 469
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELE 767
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   470 EDKEEEMLQLME---KLAALQMENAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKQEKQEDQESAATATkrrgdspSK 546
Cdd:TIGR02168  768 ERLEEAEEELAEaeaEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER-------RL 840
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   547 THLTEESPRLGKQRKCTEGEQSDASNSGDWL--ALNSELQRSQSQDEELTSLRQRVAELEEELKAAkEGRSLTPESRSKE 624
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELesELEALLNERASLEEALALLRSELEELSEELREL-ESKRSELRRELEE 919
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   625 LETSLEQMQRAYEDCE---DYWQTKLSEERQLfekERQIYEDEQHESDKKFTELMEKVREYEEQFSKDGR--LSPIDERD 699
Cdd:TIGR02168  920 LREKLAQLELRLEGLEvriDNLQERLSEEYSL---TLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnLAAIEEYE 996
                          330       340       350
                   ....*....|....*....|....*....|.
gi 442626161   700 MLEQQYSELEAEAAQLRsSSIQMLEEKAQEI 730
Cdd:TIGR02168  997 ELKERYDFLTAQKEDLT-EAKETLEEAIEEI 1026
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
393-746 3.10e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  393 KLEAQLKSLEQEEIRlrTELELVRTENTELESEqqkahiqITELLEQNIKLNQELAQTSSSIGGTPEHSPLRPRRHSEDK 472
Cdd:PRK03918  376 RLKKRLTGLTPEKLE--KELEELEKAKEEIEEE-------ISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELT 446
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  473 EEEMLQLMEKLAAlqmENAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKQEKQEDQESAATATKRRGDSPSKTHLTEE 552
Cdd:PRK03918  447 EEHRKELLEEYTA---ELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKK 523
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  553 SPRLGKQRKCTEGEQSDASNsgdwlaLNSELQRSQSQDEELTSLRQRVAELEEELKAA-KEGRSLTPESrSKELETSLEQ 631
Cdd:PRK03918  524 AEEYEKLKEKLIKLKGEIKS------LKKELEKLEELKKKLAELEKKLDELEEELAELlKELEELGFES-VEELEERLKE 596
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  632 MQRAYEDcedYWQTKLSE-ERQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKDGRLSPIDERDMLEQQYSELEA 710
Cdd:PRK03918  597 LEPFYNE---YLELKDAEkELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSR 673
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 442626161  711 EAAQLRsSSIQMLEEKAQEISSLqseIEDLRQRLGE 746
Cdd:PRK03918  674 ELAGLR-AELEELEKRREEIKKT---LEKLKEELEE 705
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
274-738 1.81e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.40  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   274 EVNLQQLTKALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAYrqqhEENLKLRADNKAANQ-RVALLAVEVDERHA 352
Cdd:pfam05483  316 EEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSL----EELLRTEQQRLEKNEdQLKIITMELQKKSS 391
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   353 SLEDNSK----KQVQqLEQRHASMVREITLRMTND---------RDHWTSMTGKLEAQLKSLEQEEIR------------ 407
Cdd:pfam05483  392 ELEEMTKfknnKEVE-LEELKKILAEDEKLLDEKKqfekiaeelKGKEQELIFLLQAREKEIHDLEIQltaiktseehyl 470
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   408 -----LRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQTSSSIggtpehsplrprRHSEDKEEEMLQLMEK 482
Cdd:pfam05483  471 kevedLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDI------------INCKKQEERMLKQIEN 538
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   483 LAALQMenaQLRDktdeltiEIESLNVELIRSKTKAKKQEKQekqedqesaataTKRRGDSPSKTHLTEESPRLGKQRKC 562
Cdd:pfam05483  539 LEEKEM---NLRD-------ELESVREEFIQKGDEVKCKLDK------------SEENARSIEYEVLKKEKQMKILENKC 596
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   563 TEGEQSDASNSGDWLALNSE----LQRSQSQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETSleqmqrayed 638
Cdd:pfam05483  597 NNLKKQIENKNKNIEELHQEnkalKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDK---------- 666
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   639 cedywqtKLSEERQLFEKER-QIYEDE----QHESDK----KFTELMEKVREYEEQFSKdgrlsPIDERDMLEQQYSELE 709
Cdd:pfam05483  667 -------KISEEKLLEEVEKaKAIADEavklQKEIDKrcqhKIAEMVALMEKHKHQYDK-----IIEERDSELGLYKNKE 734
                          490       500
                   ....*....|....*....|....*....
gi 442626161   710 AEAAQLRSSSIQMLEEKAQEISSLQSEIE 738
Cdd:pfam05483  735 QEQSSAKAALEIELSNIKAELLSLKKQLE 763
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
271-740 7.11e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.42  E-value: 7.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  271 EEEEVNLQQLTKALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAyRQQHEENLKLRADNKAANQRVALLAVEVDER 350
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE-LAEAEEALLEAEAELAEAEEELEELAEELLE 390
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  351 HASLEDNSKKQVQQLEQRHASMVREITLRMTNDRDhwtsmtgkLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAH 430
Cdd:COG1196   391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEE--------LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  431 IQITELLEQNIKLNQELAQTSSSIGGtpehspLRPRRHSEDKEEEMLQLMEKLAALQMENAQLRDKTDELTIEI------ 504
Cdd:COG1196   463 ELLAELLEEAALLEAALAELLEELAE------AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaay 536
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  505 --------ESLNVELIRSKTKAKKQEKQEKQEDQESAAT------ATKRRGDSPSKTHLTEESPRLGKQRKCTEGEQSDA 570
Cdd:COG1196   537 eaaleaalAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpldkIRARAALAAALARGAIGAAVDLVASDLREADARYY 616
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  571 SNSGDWLALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETSLEQMQRAyedcEDYWQTKLSEE 650
Cdd:COG1196   617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL----EELAERLAEEE 692
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  651 RQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQfskDGRLSPIDERDMLEQQYSELEAEAAQLRSSSIQMLEEKAQEI 730
Cdd:COG1196   693 LELEEALLAEEEEERELAEAEEERLEEELEEEALE---EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
                         490
                  ....*....|
gi 442626161  731 SSLQSEIEDL 740
Cdd:COG1196   770 ERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
393-730 1.65e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 1.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   393 KLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQE---LAQTSSSIGGTPEHSPLRPRRHS 469
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELE 767
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   470 EDKEEEMLQLME---KLAALQMENAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKQEKQEDQESAATATkrrgdspSK 546
Cdd:TIGR02168  768 ERLEEAEEELAEaeaEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER-------RL 840
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   547 THLTEESPRLGKQRKCTEGEQSDASNSGDWL--ALNSELQRSQSQDEELTSLRQRVAELEEELKAAkEGRSLTPESRSKE 624
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELesELEALLNERASLEEALALLRSELEELSEELREL-ESKRSELRRELEE 919
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   625 LETSLEQMQRAYEDCE---DYWQTKLSEERQLfekERQIYEDEQHESDKKFTELMEKVREYEEQFSKDGR--LSPIDERD 699
Cdd:TIGR02168  920 LREKLAQLELRLEGLEvriDNLQERLSEEYSL---TLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnLAAIEEYE 996
                          330       340       350
                   ....*....|....*....|....*....|.
gi 442626161   700 MLEQQYSELEAEAAQLRsSSIQMLEEKAQEI 730
Cdd:TIGR02168  997 ELKERYDFLTAQKEDLT-EAKETLEEAIEEI 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
458-740 7.32e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 7.32e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   458 PEHSPLRPRRHSEDKEEEMLQLMEKLAALQMENAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKQEKQEDQESAATAT 537
Cdd:TIGR02168  668 TNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   538 KRRGDSPSKTHLTEEspRLGKQRKCTEGEQSDASNSGDWLALNSELQRSQSQ----DEELTSLRQRVAELEEEL------ 607
Cdd:TIGR02168  748 RIAQLSKELTELEAE--IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElkalREALDELRAELTLLNEEAanlrer 825
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   608 -------KAAKEGRSLTPESRSKELETSLEQMQRAYEDCEDYwQTKLSEERQLFEKERQIYEDEQHESDKKFTELMEKVR 680
Cdd:TIGR02168  826 leslerrIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL-IEELESELEALLNERASLEEALALLRSELEELSEELR 904
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   681 EYEEQFSK--------DGRLSPIDER--------DMLEQQYSE---LEAEAAQLRSSSIQMLEEKAQ-EISSLQSEIEDL 740
Cdd:TIGR02168  905 ELESKRSElrreleelREKLAQLELRleglevriDNLQERLSEeysLTLEEAEALENKIEDDEEEARrRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
282-743 6.80e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 6.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  282 KALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAYRQQHEEnlkLRADNKAANQRVALLAVEVdERHASLEDNSKKQ 361
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE---LELELEEAQAEEYELLAEL-ARLEQDIARLEER 310
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  362 VQQLEQRHAsmvreitlRMTNDRDHWTSMTGKLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNI 441
Cdd:COG1196   311 RRELEERLE--------ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  442 KLNQELAQTSSSIGGTpEHSPLRPRRHSEDKEEEMLQLMEKLAALQMENAQLRDKTDELTIEIESLNVELIRSKTKAKKQ 521
Cdd:COG1196   383 ELAEELLEALRAAAEL-AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  522 EKQEKQEDQESAATATKRRGDSPSKTHLTEESPRLGKQRKCTEGEQSD-------ASNSGDWLALNSELQRSQSQDEEL- 593
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaalllAGLRGLAGAVAVLIGVEAAYEAALe 541
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  594 -----------TSLRQRVAELEEELKAAKEGR----SLTPESRSKELETSLEQMQRAYE----DCEDYWQTKLSEERQLF 654
Cdd:COG1196   542 aalaaalqnivVEDDEVAAAAIEYLKAAKAGRatflPLDKIRARAALAAALARGAIGAAvdlvASDLREADARYYVLGDT 621
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  655 EKERQIYEDEQHESDKKFTELMEKVREyEEQFSKDGRLSPIDERDMLEQQYSELEAEAAQLRSSSIQMLEEKAQEISSLQ 734
Cdd:COG1196   622 LLGRTLVAARLEAALRRAVTLAGRLRE-VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                  ....*....
gi 442626161  735 SEIEDLRQR 743
Cdd:COG1196   701 AEEEEEREL 709
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
578-754 2.21e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 2.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   578 ALNSELQRSQSQDEEL----TSLRQRVAELEEELKAAKEGRSlTPESRSKELETSLEQMQRAYEdcedywqtKLSEERQL 653
Cdd:TIGR02168  257 ELTAELQELEEKLEELrlevSELEEEIEELQKELYALANEIS-RLEQQKQILRERLANLERQLE--------ELEAQLEE 327
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   654 FEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKDGRlspidERDMLEQQYSELEAEAAQLRSSSIQMLEEKAQ---EI 730
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELEA-----ELEELESRLEELEEQLETLRSKVAQLELQIASlnnEI 402
                          170       180
                   ....*....|....*....|....
gi 442626161   731 SSLQSEIEDLRQRLGESVEILTGA 754
Cdd:TIGR02168  403 ERLEARLERLEDRRERLQQEIEEL 426
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
392-749 3.37e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.69  E-value: 3.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   392 GKLEAQLKSLEQEEirLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQTSSSIggtpehsplrprrhSED 471
Cdd:TIGR02169  221 REYEGYELLKEKEA--LERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKI--------------KDL 284
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   472 KEEEMLQLMEKLAALQMENAQLRDKTDELTIEIESLNVEliRSKTKAKKQEKQEKQEDQESAATATKRRgdspsKTHLTE 551
Cdd:TIGR02169  285 GEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEER--LAKLEAEIDKLLAEIEELEREIEEERKR-----RDKLTE 357
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   552 ESprlgkqrkctegeqsdasnsgdwlalnselqrsQSQDEELTSLRQRVAELEEELKAAKEgrsltpesRSKELETSLEQ 631
Cdd:TIGR02169  358 EY---------------------------------AELKEELEDLRAELEEVDKEFAETRD--------ELKDYREKLEK 396
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   632 MQRAYEDCEDYWQTKLSEERQLFEKERQIY------EDEQHESDKKFTELMEKVREYEEQFSkdgrlSPIDERDMLEQQY 705
Cdd:TIGR02169  397 LKREINELKRELDRLQEELQRLSEELADLNaaiagiEAKINELEEEKEDKALEIKKQEWKLE-----QLAADLSKYEQEL 471
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 442626161   706 SELEAEAAQLRSssiqmleekaqEISSLQSEIEDLRQRLGESVE 749
Cdd:TIGR02169  472 YDLKEEYDRVEK-----------ELSKLQRELAEAEAQARASEE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
394-746 1.40e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 1.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  394 LEAQLKSLEQEEIRLRTELELvRTENTELESEQQKAHIQitelleqniKLNQELAQTSSSIggtpehsplrprrhsEDKE 473
Cdd:COG1196   198 LERQLEPLERQAEKAERYREL-KEELKELEAELLLLKLR---------ELEAELEELEAEL---------------EELE 252
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  474 EEMLQLMEKLAALQMENAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKqekqedqesaatatkrrgdspSKTHLTEES 553
Cdd:COG1196   253 AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ---------------------DIARLEERR 311
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  554 PRLGKQRkctegEQSDAsnsgdwlALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETSLEQMQ 633
Cdd:COG1196   312 RELEERL-----EELEE-------ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  634 RAYEDcedyWQTKLSEERQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKDGRLSPIDERDMLEQQYSELEAEAA 713
Cdd:COG1196   380 ELEEL----AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455
                         330       340       350
                  ....*....|....*....|....*....|...
gi 442626161  714 QLRSSSIQMLEEKAQEISSLQSEIEDLRQRLGE 746
Cdd:COG1196   456 EEEEALLELLAELLEEAALLEAALAELLEELAE 488
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
319-691 3.33e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.60  E-value: 3.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   319 YRQQHEENLKLRADNKAANQRVALLAVEVDERHASLEDNSKKQVQQLEQRHAsmVREITLRMTNDRdhWTSMTGKLEA-- 396
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAE--LRELELALLVLR--LEELREELEElq 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   397 -QLKSLEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQTSSSIGGTPEhSPLRPRRHSEDKEEE 475
Cdd:TIGR02168  246 eELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE-RLANLERQLEELEAQ 324
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   476 MLQLMEKLAALQMENAQLRDKTDELTIEIESLNVELIRSKTKAKKqekqekqedqesaatatkrrgdspSKTHLTEESPR 555
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE------------------------LESRLEELEEQ 380
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   556 LGKQRKctegEQSDASNSGDwlALNSELQRSQSQDEELTSLRQR-VAELEEELKAAKEGRSLTPESRSKELETSLEQMQR 634
Cdd:TIGR02168  381 LETLRS----KVAQLELQIA--SLNNEIERLEARLERLEDRRERlQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 442626161   635 AYEDCEDYWQTKLSEERQLFEKERQIYEDEQHESDKKftELMEKVREYEEQFSKDGR 691
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAERELAQLQARL--DSLERLQENLEGFSEGVK 509
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
588-699 1.55e-05

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 49.31  E-value: 1.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  588 SQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETSLEQMQRAYEDCEDYWQtklsEERQLFEKERQIYEdEQHE 667
Cdd:COG0542   408 SKPEELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWE----AEKELIEEIQELKE-ELEQ 482
                          90       100       110
                  ....*....|....*....|....*....|....
gi 442626161  668 SDKKFTELMEKVREYEEQFSKDGRLSP--IDERD 699
Cdd:COG0542   483 RYGKIPELEKELAELEEELAELAPLLReeVTEED 516
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
317-637 1.94e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 1.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  317 LAYRQQHEENLKLRADNKAANQRVALLAVEVDERHASLEDNsKKQVQQLEQRhasmvreitlrmtndrdhwtsmtgkLEA 396
Cdd:COG1196   232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL-RLELEELELE-------------------------LEE 285
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  397 QLKS---LEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQTSSSIggtpehsplrprrhsEDKE 473
Cdd:COG1196   286 AQAEeyeLLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL---------------EEAE 350
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  474 EEMLQLMEKLAALQMENAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKQEKQEDQESAATATKRRgdspskTHLTEES 553
Cdd:COG1196   351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE------RLEEELE 424
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  554 PRLGKQRKCTEGEQSDAsnsgdwLALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRS--LTPESRSKELETSLEQ 631
Cdd:COG1196   425 ELEEALAELEEEEEEEE------EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAelLEELAEAAARLLLLLE 498

                  ....*.
gi 442626161  632 MQRAYE 637
Cdd:COG1196   499 AEADYE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
578-771 2.06e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 2.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  578 ALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRSLTpESRSKELETSLEQMQRAYEDCEdywQTKLSEERQLFEKE 657
Cdd:COG1196   303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAE---EALLEAEAELAEAE 378
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  658 RQIYEDEQHESDKKFTELMEKVREYEEQFSKDGRLspiDERDMLEQQYSELEAEAAQLRSSSIQmLEEKAQEISSLQSEI 737
Cdd:COG1196   379 EELEELAEELLEALRAAAELAAQLEELEEAEEALL---ERLERLEEELEELEEALAELEEEEEE-EEEALEEAAEEEAEL 454
                         170       180       190
                  ....*....|....*....|....*....|....
gi 442626161  738 EDLRQRLGESVEILTGACELTSESVAQLSAEAGK 771
Cdd:COG1196   455 EEEEEALLELLAELLEEAALLEAALAELLEELAE 488
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
393-746 3.10e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  393 KLEAQLKSLEQEEIRlrTELELVRTENTELESEqqkahiqITELLEQNIKLNQELAQTSSSIGGTPEHSPLRPRRHSEDK 472
Cdd:PRK03918  376 RLKKRLTGLTPEKLE--KELEELEKAKEEIEEE-------ISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELT 446
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  473 EEEMLQLMEKLAAlqmENAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKQEKQEDQESAATATKRRGDSPSKTHLTEE 552
Cdd:PRK03918  447 EEHRKELLEEYTA---ELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKK 523
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  553 SPRLGKQRKCTEGEQSDASNsgdwlaLNSELQRSQSQDEELTSLRQRVAELEEELKAA-KEGRSLTPESrSKELETSLEQ 631
Cdd:PRK03918  524 AEEYEKLKEKLIKLKGEIKS------LKKELEKLEELKKKLAELEKKLDELEEELAELlKELEELGFES-VEELEERLKE 596
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  632 MQRAYEDcedYWQTKLSE-ERQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKDGRLSPIDERDMLEQQYSELEA 710
Cdd:PRK03918  597 LEPFYNE---YLELKDAEkELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSR 673
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 442626161  711 EAAQLRsSSIQMLEEKAQEISSLqseIEDLRQRLGE 746
Cdd:PRK03918  674 ELAGLR-AELEELEKRREEIKKT---LEKLKEELEE 705
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
298-746 3.69e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 3.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  298 SNMLRALAALQATELGNYRLAYRQQHEENLKLRADN-KAANQRVALLAVEVDERHASLEdnskkQVQQLEQRHASMVREI 376
Cdd:COG4717    37 STLLAFIRAMLLERLEKEADELFKPQGRKPELNLKElKELEEELKEAEEKEEEYAELQE-----ELEELEEELEELEAEL 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  377 TlRMTNDRDHWtsmtgKLEAQLKSLEQEEIRLRTELELVRTENTELESEQQkahiQITELLEQNIKLNQELAQTSSSIGg 456
Cdd:COG4717   112 E-ELREELEKL-----EKLLQLLPLYQELEALEAELAELPERLEELEERLE----ELRELEEELEELEAELAELQEELE- 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  457 tpehspLRPRRHSEDKEEEMLQLMEKLAALQMENAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKQEK-QEDQESAAT 535
Cdd:COG4717   181 ------ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERlKEARLLLLI 254
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  536 ATKRRGDSPSKTHLTEESPRLGKQRKCTEGEQSDAsnsgdWLALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRS 615
Cdd:COG4717   255 AAALLALLGLGGSLLSLILTIAGVLFLVLGLLALL-----FLLLAREKASLGKEAEELQALPALEELEEEELEELLAALG 329
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  616 LTPESRSKELETSLEQMQRAYEDCEDYWQTKLSEERQLFEKER-QIYEDEQHESDKKFTELMEKVREYEEqfsKDGRLSP 694
Cdd:COG4717   330 LPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIaALLAEAGVEDEEELRAALEQAEEYQE---LKEELEE 406
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 442626161  695 IDERdmLEQQYSELEAEAAQLRSSSI-QMLEEKAQEISSLQSEIEDLRQRLGE 746
Cdd:COG4717   407 LEEQ--LEELLGELEELLEALDEEELeEELEELEEELEELEEELEELREELAE 457
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
558-746 7.19e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 7.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   558 KQRKCTEGEQSDASNSGDWLALNSELQRSQsqdEELTSLRQRVAELEEELKAAKEGRSlTPESRSKELETSLEQMQRAYE 637
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKLK---ERLEELEEDLSSLEQEIENVKSELK-ELEARIEELEEDLHKLEEALN 782
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   638 DCEDywqtKLSEER-QLFEKERQIYEDEQHESDKKFTELMEKV--REYEEQFSKDGRLSPIDERDMLEQQYSELEAEAAQ 714
Cdd:TIGR02169  783 DLEA----RLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLnrLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN 858
                          170       180       190
                   ....*....|....*....|....*....|..
gi 442626161   715 LRSSsiqmLEEKAQEISSLQSEIEDLRQRLGE 746
Cdd:TIGR02169  859 LNGK----KEELEEELEELEAALRDLESRLGD 886
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
587-769 1.06e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 1.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   587 QSQDEELTSLRQRVAELEEELKAAK--------------------EGRSLTPESRSKELETSLEQMQRAYEDCEDYWQtK 646
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEkalaelrkeleeleeeleqlRKELEELSRQISALRKDLARLEAEVEQLEERIA-Q 751
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   647 LSEERQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKD-GRLSPIDER-DMLEQQYSELEAEAAQLRSSsiqmLE 724
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLkEELKALREAlDELRAELTLLNEEAANLRER----LE 827
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 442626161   725 EKAQEISSLQSEIEDLRQRLG---ESVEILTGACELTSESVAQLSAEA 769
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEQIEelsEDIESLAAEIEELEELIEELESEL 875
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
321-668 1.62e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 1.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   321 QQHEENLKLRADNKAANQRVALLAvEVDERHASLEDnSKKQVQQLEQRHASMVREITLRMTNDRDHWTSMTGKLEAQLKS 400
Cdd:TIGR02169  221 REYEGYELLKEKEALERQKEAIER-QLASLEEELEK-LTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGE 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   401 LEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQtsssiggtpehspLRPRRHS-----EDKEEE 475
Cdd:TIGR02169  299 LEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE-------------ERKRRDKlteeyAELKEE 365
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   476 MLQLMEKLAALQMENAQLRDKTDELTIEIESLNVELIRSKTkakkqekqekqedqesaatatkrrgdspskthlteESPR 555
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR-----------------------------------ELDR 410
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   556 LGKQRKCTEGEQSDASNsgdwlALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRSltpesrskELETSLEQMQRA 635
Cdd:TIGR02169  411 LQEELQRLSEELADLNA-----AIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS--------KYEQELYDLKEE 477
                          330       340       350
                   ....*....|....*....|....*....|...
gi 442626161   636 YEDCEDYwQTKLSEERQLFEKERQIYEDEQHES 668
Cdd:TIGR02169  478 YDRVEKE-LSKLQRELAEAEAQARASEERVRGG 509
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
591-743 2.37e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 2.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  591 EELTSLRQRVAELEEELKAAKEGRSLTpESRSKELETSLEQMQRAYedcedyWQTKLSEERQLfekERQIyedEQHESDK 670
Cdd:COG4913   288 RRLELLEAELEELRAELARLEAELERL-EARLDALREELDELEAQI------RGNGGDRLEQL---EREI---ERLEREL 354
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  671 KftELMEKVREYEEQFSKDGRLSPIDERDMLEQQ---------YSELEAEAAQLRSSSIQMLEEKAQEISSLQSEIEDLR 741
Cdd:COG4913   355 E--ERERRRARLEALLAALGLPLPASAEEFAALRaeaaalleaLEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432

                  ..
gi 442626161  742 QR 743
Cdd:COG4913   433 RR 434
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
393-740 3.38e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 3.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   393 KLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQTSSSIGGTpehsplrpRRHSEDK 472
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN--------NKKIKEL 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   473 EEEMLQLMEKLAALQMENAQlrDKTDELTIEIESLNVELIRSKTKakkqekqekQEDQESAATATKRRGDSPSKTHLTEE 552
Cdd:TIGR04523  287 EKQLNQLKSEISDLNNQKEQ--DWNKELKSELKNQEKKLEEIQNQ---------ISQNNKIISQLNEQISQLKKELTNSE 355
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   553 SPRLGKQRKCTEGEQsdasnsgdwlALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEgrsltpesRSKELETSLEQM 632
Cdd:TIGR04523  356 SENSEKQRELEEKQN----------EIEKLKKENQSYKQEIKNLESQINDLESKIQNQEK--------LNQQKDEQIKKL 417
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   633 QRAYEDCEDYwQTKLSEERQLFEKERQIYEDEQHESDKKFTELmEKVREYEEQFSKDGRLSPIDERDMLEQQYSELEAEA 712
Cdd:TIGR04523  418 QQEKELLEKE-IERLKETIIKNNSEIKDLTNQDSVKELIIKNL-DNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKE 495
                          330       340       350
                   ....*....|....*....|....*....|....
gi 442626161   713 AQLRS--SSIQMLEEK----AQEISSLQSEIEDL 740
Cdd:TIGR04523  496 KELKKlnEEKKELEEKvkdlTKKISSLKEKIEKL 529
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
596-769 5.35e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 5.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  596 LRQRVAELEEELKAAKEGRSLTPESRSKELETSLEQMQRAYEDCEDYWQT---------KLSEERQLFEKERQIYEDEQH 666
Cdd:COG1196   198 LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAEleeleaeleELEAELAELEAELEELRLELE 277
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  667 ESDKKFTELMEKVREYEEQFSK-DGRLSPIDERDM-LEQQYSELEAEAAQLRSSSIQM---LEEKAQEISSLQSEIEDLR 741
Cdd:COG1196   278 ELELELEEAQAEEYELLAELARlEQDIARLEERRReLEERLEELEEELAELEEELEELeeeLEELEEELEEAEEELEEAE 357
                         170       180
                  ....*....|....*....|....*...
gi 442626161  742 QRLGESVEILTGACELTSESVAQLSAEA 769
Cdd:COG1196   358 AELAEAEEALLEAEAELAEAEEELEELA 385
PRK12704 PRK12704
phosphodiesterase; Provisional
619-772 6.35e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 6.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  619 ESRSKELETSLEQM-QRAYEDCEDYWQTKLSEERQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKdgrlspidE 697
Cdd:PRK12704   30 EAKIKEAEEEAKRIlEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDR--------K 101
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442626161  698 RDMLEQQYSELEAEAAQlrsssiqmLEEKAQEISSLQSEIEDLRQrlgESVEILtgaceltsESVAQLSAEAGKS 772
Cdd:PRK12704  102 LELLEKREEELEKKEKE--------LEQKQQELEKKEEELEELIE---EQLQEL--------ERISGLTAEEAKE 157
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
587-748 7.70e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 7.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  587 QSQDEELTSLRQRVAELEEELKAAKEGRSLTpESRSKELETSLEQMQRAYEDCE----------DYWQTKLSE-----ER 651
Cdd:COG1579    13 QELDSELDRLEHRLKELPAELAELEDELAAL-EARLEAAKTELEDLEKEIKRLEleieeveariKKYEEQLGNvrnnkEY 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  652 QLFEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKdgrlspiderdmLEQQYSELEAEAAQLRSSSIQMLEEKAQEIS 731
Cdd:COG1579    92 EALQKEIESLKRRISDLEDEILELMERIEELEEELAE------------LEAELAELEAELEEKKAELDEELAELEAELE 159
                         170
                  ....*....|....*..
gi 442626161  732 SLQSEIEDLRQRLGESV 748
Cdd:COG1579   160 ELEAEREELAAKIPPEL 176
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
556-749 1.30e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   556 LGKQRKCT-EGEQSDASNS--GDWLALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRSltpesrskELETSLEQM 632
Cdd:TIGR02169  636 MGKYRMVTlEGELFEKSGAmtGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELR--------RIENRLDEL 707
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   633 QRAYEDCEdywqtklsEERQLFEKERQIYEDEQHESDKKFTELMEKVREYEEqfskdGRLSPIDERDMLEQQYSELEAEA 712
Cdd:TIGR02169  708 SQELSDAS--------RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ-----EIENVKSELKELEARIEELEEDL 774
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 442626161   713 AQLRSS----SIQMLEEKAQEISSLQSEIEDLRQRLGESVE 749
Cdd:TIGR02169  775 HKLEEAlndlEARLSHSRIPEIQAELSKLEEEVSRIEARLR 815
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
265-507 1.31e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  265 HVLGFDeeeevNLQQLtKALEEELRGIDgdheqsnmlRALAALQAtelgnyRLAYRQQHEENLKLRADnkAANQRVALLA 344
Cdd:COG4913   602 YVLGFD-----NRAKL-AALEAELAELE---------EELAEAEE------RLEALEAELDALQERRE--ALQRLAEYSW 658
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  345 VEVDerHASLEdnskKQVQQLEQRHAsmvreitlRMTNDRDHWTsmtgKLEAQLKSLEQEEIRLRTELELVRTENTELES 424
Cdd:COG4913   659 DEID--VASAE----REIAELEAELE--------RLDASSDDLA----ALEEQLEELEAELEELEEELDELKGEIGRLEK 720
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  425 EQQKAhiqitellEQNIKLNQELAQTSSSIGGTPEHSPLRPRRHSEDKEEEMLQLMEKLAAlqmENAQLRDKTDELTIEI 504
Cdd:COG4913   721 ELEQA--------EEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEE---RIDALRARLNRAEEEL 789

                  ...
gi 442626161  505 ESL 507
Cdd:COG4913   790 ERA 792
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
572-751 1.43e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 1.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  572 NSGDWLALNSELQRSQSQDEELTSLRQRVAELEEELKAAkegrsltpESRSKELETSLEQMQRAyEDCEDYWQTKLSEER 651
Cdd:COG4717    69 NLKELKELEEELKEAEEKEEEYAELQEELEELEEELEEL--------EAELEELREELEKLEKL-LQLLPLYQELEALEA 139
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  652 QLFEKERQIyedeqhesdkkfTELMEKVREYEEqfskdgrlspiderdmLEQQYSELEAEAAQLRSSSIQMLE----EKA 727
Cdd:COG4717   140 ELAELPERL------------EELEERLEELRE----------------LEEELEELEAELAELQEELEELLEqlslATE 191
                         170       180
                  ....*....|....*....|....
gi 442626161  728 QEISSLQSEIEDLRQRLGESVEIL 751
Cdd:COG4717   192 EELQDLAEELEELQQRLAELEEEL 215
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
274-738 1.81e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.40  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   274 EVNLQQLTKALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAYrqqhEENLKLRADNKAANQ-RVALLAVEVDERHA 352
Cdd:pfam05483  316 EEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSL----EELLRTEQQRLEKNEdQLKIITMELQKKSS 391
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   353 SLEDNSK----KQVQqLEQRHASMVREITLRMTND---------RDHWTSMTGKLEAQLKSLEQEEIR------------ 407
Cdd:pfam05483  392 ELEEMTKfknnKEVE-LEELKKILAEDEKLLDEKKqfekiaeelKGKEQELIFLLQAREKEIHDLEIQltaiktseehyl 470
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   408 -----LRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQTSSSIggtpehsplrprRHSEDKEEEMLQLMEK 482
Cdd:pfam05483  471 kevedLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDI------------INCKKQEERMLKQIEN 538
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   483 LAALQMenaQLRDktdeltiEIESLNVELIRSKTKAKKQEKQekqedqesaataTKRRGDSPSKTHLTEESPRLGKQRKC 562
Cdd:pfam05483  539 LEEKEM---NLRD-------ELESVREEFIQKGDEVKCKLDK------------SEENARSIEYEVLKKEKQMKILENKC 596
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   563 TEGEQSDASNSGDWLALNSE----LQRSQSQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETSleqmqrayed 638
Cdd:pfam05483  597 NNLKKQIENKNKNIEELHQEnkalKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDK---------- 666
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   639 cedywqtKLSEERQLFEKER-QIYEDE----QHESDK----KFTELMEKVREYEEQFSKdgrlsPIDERDMLEQQYSELE 709
Cdd:pfam05483  667 -------KISEEKLLEEVEKaKAIADEavklQKEIDKrcqhKIAEMVALMEKHKHQYDK-----IIEERDSELGLYKNKE 734
                          490       500
                   ....*....|....*....|....*....
gi 442626161   710 AEAAQLRSSSIQMLEEKAQEISSLQSEIE 738
Cdd:pfam05483  735 QEQSSAKAALEIELSNIKAELLSLKKQLE 763
FPP pfam05911
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ...
548-715 2.14e-03

Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.


Pssm-ID: 461778 [Multi-domain]  Cd Length: 859  Bit Score: 41.97  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   548 HLTEESPRLGKQRKCTEGEQSDASnsgdwlaLNSELQRSQSQDEEltslrQRVAELEEELKAAKEGRSLtpesrskeLET 627
Cdd:pfam05911  685 RLKEEFEQLKSEKENLEVELASCT-------ENLESTKSQLQESE-----QLIAELRSELASLKESNSL--------AET 744
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   628 SLEQMQRAYEDCE---DYWQTKLSEERQLFEKerqiYEDEQHESDKKFTELMEKVREYEEQF----SKDGRLSPIDERDM 700
Cdd:pfam05911  745 QLKCMAESYEDLEtrlTELEAELNELRQKFEA----LEVELEEEKNCHEELEAKCLELQEQLerneKKESSNCDADQEDK 820
                          170
                   ....*....|....*
gi 442626161   701 LEQQYSELEAEAAQL 715
Cdd:pfam05911  821 KLQQEKEITAASEKL 835
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
303-513 2.32e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.96  E-value: 2.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  303 ALAALQATELGNyrlayrQQHEENLKLRADNKAANQRVALLAVE-----VDERHASLEdnSKKQVQQLEQRHASMVREIT 377
Cdd:PRK10929   14 SWGAYAATAPDE------KQITQELEQAKAAKTPAQAEIVEALQsalnwLEERKGSLE--RAKQYQQVIDNFPKLSAELR 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  378 LRMTNDRDHWTSMTGKLEAQlkSLEQEEIRLRTEL-ELVRtentELESEQQKAhIQITELL----EQNIKLNQELAQTSS 452
Cdd:PRK10929   86 QQLNNERDEPRSVPPNMSTD--ALEQEILQVSSQLlEKSR----QAQQEQDRA-REISDSLsqlpQQQTEARRQLNEIER 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442626161  453 SIGGTPehSPLRPRRHSedkeeemlqlmeKLAALQMENAQLRDKTDELTIEIESLN--VELIR 513
Cdd:PRK10929  159 RLQTLG--TPNTPLAQA------------QLTALQAESAALKALVDELELAQLSANnrQELAR 207
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
392-744 2.57e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 2.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  392 GKLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKahiqITELLEQNIKLNQELAQTSSSIGGTpehsplrpRRHSED 471
Cdd:PRK03918  203 EEVLREINEISSELPELREELEKLEKEVKELEELKEE----IEELEKELESLEGSKRKLEEKIREL--------EERIEE 270
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  472 KEEEMLQLMEKLAALQmENAQLRDKTDELTIEIESLNVELIR-SKTKAKKQEKQEKQEDQESAATATKRRgdspskthLT 550
Cdd:PRK03918  271 LKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREiEKRLSRLEEEINGIEERIKELEEKEER--------LE 341
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  551 EESPRLGKQRKCTEGEQSDASNSGDWLALNSELQRSQSQ---------DEELTSLRQRVAELEEELKAAKEGRSlTPESR 621
Cdd:PRK03918  342 ELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRltgltpeklEKELEELEKAKEEIEEEISKITARIG-ELKKE 420
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  622 SKELETSLEQMQRAYEDCEdYWQTKLSEERQL-----FEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKDGRLSPid 696
Cdd:PRK03918  421 IKELKKAIEELKKAKGKCP-VCGRELTEEHRKelleeYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIK-- 497
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 442626161  697 ERDMLEQqyseLEAEAAQLRSSSIQMLEEKAQEISSLQSEIEDLRQRL 744
Cdd:PRK03918  498 LKELAEQ----LKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEI 541
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
587-749 3.58e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 3.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  587 QSQDEELTSLRQRVAELEEELKAAKEgrsltpesRSKELETSLEQMQRAYEDcedywqTKLSEERQLFEKERQIYEDEQH 666
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRK--------ELEEAEAALEEFRQKNGL------VDLSEEAKLLLQQLSELESQLA 229
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  667 ESDKKFTELMEKVREYEEQFSKDGRLSPIDERD----MLEQQYSELEAEAAQLRSSsiqmLEEKAQEISSLQSEIEDLRQ 742
Cdd:COG3206   230 EARAELAEAEARLAALRAQLGSGPDALPELLQSpviqQLRAQLAELEAELAELSAR----YTPNHPDVIALRAQIAALRA 305

                  ....*..
gi 442626161  743 RLGESVE 749
Cdd:COG3206   306 QLQQEAQ 312
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
587-776 3.84e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.07  E-value: 3.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  587 QSQDEELTSLRQRVAELEEELKAAKEGRSlTPESRSKELE--TSLEqmqrayEDCEDYWQTKLSEeRQLFEKERQIYEDE 664
Cdd:PRK05771   89 KDVEEELEKIEKEIKELEEEISELENEIK-ELEQEIERLEpwGNFD------LDLSLLLGFKYVS-VFVGTVPEDKLEEL 160
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  665 QHESDKKFTELMEKVREYeeqfskdGRLSPIDERDMLEQQYSEL---EAEAAQLRSSSI--QMLEEKAQEISSLQSEIED 739
Cdd:PRK05771  161 KLESDVENVEYISTDKGY-------VYVVVVVLKELSDEVEEELkklGFERLELEEEGTpsELIREIKEELEEIEKERES 233
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 442626161  740 LRQRLGESVEILTgacELTSESVAQLSAEAGKSPASS 776
Cdd:PRK05771  234 LLEELKELAKKYL---EELLALYEYLEIELERAEALS 267
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
259-439 3.85e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 3.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   259 NTRNLLHVLGFDEEEEVNLQQLTKA---LEEELRGIDGDHEQSNMLRALAALQATELGNYRLAYRQQHEENLKLRADNKA 335
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAeeeLAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   336 ANQRVALLAVEVDERHASLEDNSKkQVQQLEQRHASMVREITlRMTNDRDHWT--------------SMTGKLEAQLKSL 401
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSE-DIESLAAEIEELEELIE-ELESELEALLnerasleealallrSELEELSEELREL 906
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 442626161   402 EQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQ 439
Cdd:TIGR02168  907 ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
467-751 4.09e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.50  E-value: 4.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   467 RHSEDKEEEMLQLMEklaalqmENAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKQEKQEDQESAATATKRRGDSPSK 546
Cdd:pfam02463  166 RLKRKKKEALKKLIE-------ETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   547 THLTEESPRLGKQRKctEGEQSDASNSGDWLALNSELQRSQSQDEELTSLRQ-RVAELEEELKAAKEGRSLTPESRSKEL 625
Cdd:pfam02463  239 IDLLQELLRDEQEEI--ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELkLLAKEEEELKSELLKLERRKVDDEEKL 316
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161   626 ETSLEQMQRAYEDCEDYWQTKLSEERQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKDGRLSPIDERDMLEQQY 705
Cdd:pfam02463  317 KESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEE 396
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 442626161   706 SELEAEAAQLRSSSIQMLEEKAQEISSLQSEIEDLRQRLGESVEIL 751
Cdd:pfam02463  397 LELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELK 442
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
392-768 4.38e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.18  E-value: 4.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  392 GKLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQTSSSIGGTPEhSPLRPRRHSED 471
Cdd:PRK02224  338 QAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPV-DLGNAEDFLEE 416
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  472 KEEEMLQLMEKLAALQM----------ENAQLR------------------DKTDELTIEIESLNVELirSKTKAKKQEK 523
Cdd:PRK02224  417 LREERDELREREAELEAtlrtarerveEAEALLeagkcpecgqpvegsphvETIEEDRERVEELEAEL--EDLEEEVEEV 494
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  524 QEKQEDQESAATATKRRGDSPSKTHLTEEspRLGKQRKCTEGEQSDASNSGDWLA-LNSELQ----RSQSQDEELTSLRQ 598
Cdd:PRK02224  495 EERLERAEDLVEAEDRIERLEERREDLEE--LIAERRETIEEKRERAEELRERAAeLEAEAEekreAAAEAEEEAEEARE 572
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  599 RVAELEEELKAAKEGRsltpeSRSKELETSLEqmqrAYEDCEDYWQTkLSEERqlfeKERQIYEDEQHEsdkKFTELMEK 678
Cdd:PRK02224  573 EVAELNSKLAELKERI-----ESLERIRTLLA----AIADAEDEIER-LREKR----EALAELNDERRE---RLAEKRER 635
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  679 VREYEEQFSKDGRLSPIDERDMLEQQYSELEAEAAQLRS------SSIQMLEEKAQEISSLQSEIEDLRQRLgESVEILT 752
Cdd:PRK02224  636 KRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREerddlqAEIGAVENELEELEELRERREALENRV-EALEALY 714
                         410
                  ....*....|....*.
gi 442626161  753 GACELTSESVAQLSAE 768
Cdd:PRK02224  715 DEAEELESMYGDLRAE 730
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
575-746 4.49e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 4.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  575 DWLALNSELQRSQSQDEELTSLRQRVAELEEELKAAKE-------------GRSLTPESRSKELETSLEQMQRAYEDCED 641
Cdd:COG4913   662 DVASAEREIAELEAELERLDASSDDLAALEEQLEELEAeleeleeeldelkGEIGRLEKELEQAEEELDELQDRLEAAED 741
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  642 Y---WQTKLSEER-------QLFEKERQIYEDEQHESDKK----FTELMEKVREYEEQF---SKDGRLSPIDERD---ML 701
Cdd:COG4913   742 LarlELRALLEERfaaalgdAVERELRENLEERIDALRARlnraEEELERAMRAFNREWpaeTADLDADLESLPEylaLL 821
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 442626161  702 EQQYS----ELEAEAAQLRSSsiQMLEEKAQEISSLQSEIEDLRQRLGE 746
Cdd:COG4913   822 DRLEEdglpEYEERFKELLNE--NSIEFVADLLSKLRRAIREIKERIDP 868
PRK12704 PRK12704
phosphodiesterase; Provisional
591-729 4.56e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.92  E-value: 4.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  591 EELTSLRQrvaELEEELKaakegrsltpeSRSKELETSLEQMQRAYEDCEDYWQTkLSEERQLFEKERQIYEDEQHESDK 670
Cdd:PRK12704   64 EEIHKLRN---EFEKELR-----------ERRNELQKLEKRLLQKEENLDRKLEL-LEKREEELEKKEKELEQKQQELEK 128
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  671 KFTELMEKVREYEEQFSKDGRLSPIDERDM-LEQQYSELEAEAAQLrsssIQMLEEKAQE 729
Cdd:PRK12704  129 KEEELEELIEEQLQELERISGLTAEEAKEIlLEKVEEEARHEAAVL----IKEIEEEAKE 184
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
340-572 5.72e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.13  E-value: 5.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  340 VALLAVEVDERHASLEDNSKKQVQQLEQRHASMVREITlRMTNDRDhwtsmtgKLEAQLKSLEQEEIRLRTELELVRTEN 419
Cdd:COG4942     7 LALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELA-ALKKEEK-------ALLKQLAALERRIAALARRIRALEQEL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  420 TELESEQQKAHIQITELLEQNIKLNQELAQTSSSIGGTPEHSPLRPRRHSEDKEE--EMLQLM--------EKLAALQME 489
Cdd:COG4942    79 AALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDavRRLQYLkylaparrEQAEELRAD 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  490 NAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKQEKQEDQESAATATKRRGDSPSKTHLTEESPRLGKQRKCTEGEQSD 569
Cdd:COG4942   159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238

                  ...
gi 442626161  570 ASN 572
Cdd:COG4942   239 AAE 241
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
549-760 9.64e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 40.02  E-value: 9.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  549 LTEESPRLGKQRKCTEGEQSDASNSGDWLALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSK----- 623
Cdd:PRK02224  164 LEEYRERASDARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEadevl 243
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  624 -ELETSLEQMQRAYEDCEDYWQTKLSEERqlfekERQIYEDEQHESDKKFTELMEkvrEYEEQFSKDGRLSPIDERdmLE 702
Cdd:PRK02224  244 eEHEERREELETLEAEIEDLRETIAETER-----EREELAEEVRDLRERLEELEE---ERDDLLAEAGLDDADAEA--VE 313
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442626161  703 QQYSELEAEAAQLRSSsiqmLEEKAQEISSLQSEIEDLRQRL----GESVEILTGACELTSE 760
Cdd:PRK02224  314 ARREELEDRDEELRDR----LEECRVAAQAHNEEAESLREDAddleERAEELREEAAELESE 371
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
579-746 9.64e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 40.05  E-value: 9.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  579 LNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETS-LEQMQRAYEDCEDYWQTKLSE-ERQLFEK 656
Cdd:PRK03918  247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIkLSEFYEEYLDELREIEKRLSRlEEEINGI 326
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  657 ERQIYEDEQHES------------DKKFTELMEKVREYEEQFSKDGRLSPIDER------DMLEQQYSELEAEAAQLRSS 718
Cdd:PRK03918  327 EERIKELEEKEErleelkkklkelEKRLEELEERHELYEEAKAKKEELERLKKRltgltpEKLEKELEELEKAKEEIEEE 406
                         170       180
                  ....*....|....*....|....*...
gi 442626161  719 siqmLEEKAQEISSLQSEIEDLRQRLGE 746
Cdd:PRK03918  407 ----ISKITARIGELKKEIKELKKAIEE 430
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
278-436 9.70e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.90  E-value: 9.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626161  278 QQLTKALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAYRQQHEENlklradnkaANQRVALLAVEVDERHASLEdn 357
Cdd:COG4913   287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGN---------GGDRLEQLEREIERLERELE-- 355
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442626161  358 skkQVQQLEQRHASMVREITLRMTNDRDHWTSMTGKLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAHIQITEL 436
Cdd:COG4913   356 ---ERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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