|
Name |
Accession |
Description |
Interval |
E-value |
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
161-649 |
2.91e-169 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 489.84 E-value: 2.91e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 161 LCGLYVMIIWEIVNRTFAAIIASTLSVGILAALNSrPSMATIMGWIDVETLLLLFGMMILVAILSETGVFDYLAVYAYKI 240
Cdd:cd01116 1 FIITYALIIFEKVHRTVAALAGALWLVILGLATLS-PDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 241 TNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIIASnsy 320
Cdd:cd01116 80 SKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIGS--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 321 isKNGVNFAVFTLHMLPGVLLVMVQTYIQLRFKFRNISDLQFKDSPEveelrheihvwkraaaslsayskdeelvrqtlm 400
Cdd:cd01116 157 --AAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLA--------------------------------- 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 401 kkvnrlkrslkkrmtaviepapnyqqtLANLQAKYPIRNKPLLIKCSAALVFVISLFFLHSVPELqrlSLGWTALLGAIF 480
Cdd:cd01116 202 ---------------------------LAELEPKYPIKDKVLLLKSLTILTLVIIGFVLHSPLGV---SLGWIALLGALL 251
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 481 LIILADIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGIILGvgedrRLMVAILIILWVSAVASAFVD 560
Cdd:cd01116 252 LLLLADKLDFEDVLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILG-----RIAVAVILILWISALLSAFID 326
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 561 NIPLTTMMVKITISLAqnSTLNLPLQPLVWALALGACLGGNGTLIGASANVVCAGVAEQHGYKFTFLQFFKVGFPIMIGS 640
Cdd:cd01116 327 NIPVTATMIPIVKDLA--SQLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWEFLKVGFPIMLVS 404
|
....*....
gi 442626004 641 IIVTTGYLL 649
Cdd:cd01116 405 LILATVYLL 413
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
155-650 |
1.20e-101 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 316.30 E-value: 1.20e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 155 IYAAAVLCGLYVMIIWEI--VNRTFAAIIASTLSVGILAAlnsrpSMATIMGWIDVETLLLLFGMMILVAILSETGVFDY 232
Cdd:COG1055 3 ILALAIFVLTYLLIILEPrgLNRAVAALLGAALLLLLGVV-----SLEDALEAIDWNTILFLLGMMIIVAILDESGFFEW 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 233 LAVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPN 312
Cdd:COG1055 78 LAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNPTN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 313 VIIASNSyisknGVNFAVFTLHMLPGVLLVMVQTYIQLRFKFRNisDLQFKDSPEVEElrheihvwkraaaslsayskde 392
Cdd:COG1055 158 IMIASAG-----GLSFLDFLANLFPPSLVSLLVTLLVLYLLFRK--ELPAAPDLEDDP---------------------- 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 393 elvrqtlmkkvnrlkrslkkrmtaviepapnyqqtlanlqaKYPIRNKPLLIKCSAALVFVISLFFLHSVPelqRLSLGW 472
Cdd:COG1055 209 -----------------------------------------KEAIKDRRLLRISLLVLALLLVGFVLHSFL---GLPPAL 244
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 473 TALLGAIFLIILADIeDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGIILGvgedrRLMVAILIILWVS 552
Cdd:COG1055 245 IALLGAAVLLLLARV-DVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGG-----NLLLAALLILWLS 318
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 553 AVASAFVDNIPLTTMMvkitISLAQNSTLNLPLQPLVWALALGACLGGNGTLIGASANVVCAGVAEQHGYKFTFLQFFKV 632
Cdd:COG1055 319 AILSAVVDNVPLVAAL----LPLIPDLGATGNPEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFGEFLKV 394
|
490
....*....|....*...
gi 442626004 633 GFPIMIGSIIVTTGYLLV 650
Cdd:COG1055 395 GLPLTLLTLLIALLYLLL 412
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
165-648 |
4.68e-94 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 295.70 E-value: 4.68e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 165 YVMIIWEIVNRTFAAIIASTLSVGILAAlnsrpSMATIMGWIDVETLLLLFGMMILVAILSETGVFDYLAVYAYKITNGH 244
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVV-----SPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 245 VWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIIASnsyisKN 324
Cdd:cd00625 76 RRLLLLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSPPVPLLLALAFAANIGGAATPIGNPPNLIIAS-----LS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 325 GVNFAVFTLHMLPGVLLVMVQTYIQLRFKFRNISDLQFKDSPEVeelrheihvwkraaaslsayskdeelvrqtlmkkvn 404
Cdd:cd00625 151 GLGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLLLPDEDKLTV------------------------------------ 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 405 rlkrslkkrmtaviepapnyqqtLANLQAKYPIRNKPLLIKCSAALVFVISLFFLhsvpelqrLSLGWTALLGAIFLIIL 484
Cdd:cd00625 195 -----------------------LAEPLPARPLLKKFLLLALLLLLLFVLLFFFL--------IPLGLIALLGALLLLLL 243
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 485 ADIE-DMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGIILGvgedrRLMVAILIILWVSAVASAFVDNIP 563
Cdd:cd00625 244 LVRGlDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALVGL-----PPLAALLLIGLLSALLSNFISNVP 318
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 564 LTTMMVKITISLAqnstlnlPLQPLVWALALGACLGGNGTLIGASANVVCAGVAEQHGYKFTFLQFFKVGFPIMIGSIIV 643
Cdd:cd00625 319 TVALLLPIAASLA-------PPEPAWLALALGSTLGGNLTLIGSLANLIPLGAAENAGVGISFGEFLKVGLPLTLLSLVV 391
|
....*
gi 442626004 644 TTGYL 648
Cdd:cd00625 392 SLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
165-595 |
2.45e-75 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 244.91 E-value: 2.45e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 165 YVMIIWEIVNRTFAAIIastlsVGILAALNSRPSMATIMGWIDVETLLLLFGMMILVAILSETGVFDYLAVYAYKITNGH 244
Cdd:pfam03600 1 YVLIITEKLPRDVVALL-----GAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 245 VWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIIASNSYISkn 324
Cdd:pfam03600 76 PRRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNIIIASALGLS-- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 325 gvnFAVFTLHMLPGVLLVMVQT-YIQLRFKFRNISDLQFKDSPEVEELRheihvwkraaaslsayskdeelvrqtlmkkv 403
Cdd:pfam03600 154 ---FGDFGFFMFPPVGVALLLVgLLPLLLIFRKLLPVRKEEEAELEELR------------------------------- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 404 nrlkrslkkrmtaviepapnyqqtlanlqaKYPIRNKPLLIKCSAALVFVISLFFLHSVpelqrlslgwtALLGAIFLII 483
Cdd:pfam03600 200 ------------------------------KRAIKDKLLLAISALVLALVILGFLLLSV-----------LALAGALLLL 238
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 484 LADIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGIIlgvgedrRLMVAILIILWVSAVASAFVDNIP 563
Cdd:pfam03600 239 LTGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGLS-------GLLVALALILWLSALLSAFISNVP 311
|
410 420 430
....*....|....*....|....*....|..
gi 442626004 564 LTTMMVKITISLAQNSTLNlPLQPLVWALALG 595
Cdd:pfam03600 312 TAALMAPIIVGMAPAAGLG-DPDPLAWALAVG 342
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
174-648 |
2.27e-44 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 163.22 E-value: 2.27e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 174 NRTFAAIIASTLSVGILAalnsrPSMATIMGWIDVETLLLLFGMMILVAILSETGVFDYLAVY-AYKITNGhvWPLINCL 252
Cdd:cd01117 12 DRWAIALLGAALMLLFGV-----ISLEDAPAAIDLDTIILLFGLMVVSAALELSGFFDALGSRiLVKAGSP--RRLLFLL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 253 CLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIIASNSyisknGVNFAVFT 332
Cdd:cd01117 85 VLLSGILSALLTNDTACLVFTPIVLELARVAGLPPIPLLLALATAANIGSAATPIGNPQNLLIASES-----GISFPFFL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 333 LHMLPGVLLVMVQTYIQLRFKFrnisdlqfkdspeveelrheihvwkraaaslsayskdeelvrqtlmkkvnRLKRSLKK 412
Cdd:cd01117 160 AAMAPLALLGLLLLLILLLVLF--------------------------------------------------PGELKGLP 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 413 RMTAVIEPAPNyqqtlanlqakYPIRNKPLLIKCSAALVFVISLFFLHSVpelqrlslgWTALLGAIfLIILADIEDMEA 492
Cdd:cd01117 190 LDKATKEEGVG-----------ARKLAVKLLVLILLLLVAFLALLGVIPL---------WTAALVAA-VLLLLTRLKPRR 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 493 ILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGIilgvgedrrlmVAILIILWVSAVASAFVDNIPLTTMMVKIT 572
Cdd:cd01117 249 VLKKVDWGLLLFFAGLFILVGGFAQGLPLEGLSRLLPLL-----------DSVLSLFLVSIGLSQLISNVPAVLLLLPFL 317
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442626004 573 ISLAQNSTLnlplqplvwALALGACLGGNGTLIGASANVVCAGVAEQHGYKFTFLQFFKVGFPIMIGSIIVTTGYL 648
Cdd:cd01117 318 PSADEKDWL---------LLAAGSTIAGNLTLLGSAANLIVAEAAERRGVRLSFGEFLKYGVPLTLLTAAIGILWL 384
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
215-650 |
7.98e-31 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 124.11 E-value: 7.98e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 215 FGMMILVAILSETGVFDYLAVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLN-----PVP 289
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEkrskfGSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 290 ILMCMVIYSNIGGALTPVGDPPNVIIASnsYISKN---GVNFAVFTLHMLPGVLLVMVQTYIQLRFKFRnisdlqfkdsP 366
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAG--LLEEAtgiPISFFEWMLVGLPVALVGLLLLWLVLYRLLP----------P 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 367 EVEELRHEIHVWKRAAASLSAYSKDEelvrqtlmkkvnrlkrslkKRMTAVIepapnyqqtlanlqakypirnkpllikc 446
Cdd:COG0471 149 EIKEVPGSKEVIREELAELGPLSRRE-------------------KIALAIF---------------------------- 181
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 447 sAALVFVISLFFLHSVPelqrlsLGWTALLGAIFLIILaDIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGN 526
Cdd:COG0471 182 -ALTVLLWITGSLHGIP------IAVVALLGAVLLLLT-GVLTWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLAD 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 527 MTEGIILGVGedrrLMVAILIILWVSAVASAFVDNIPLTTMMVKITISLAQnsTLNLPLQPLVWALALGAcLGGNGTLIG 606
Cdd:COG0471 254 ALLPLLGGLS----PLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQ--ALGVNPLPLALAVAFAA-SCAFLLPVG 326
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 442626004 607 ASANVVCAGVaeqhGYkFTFLQFFKVGFPIMIGSIIVTTGYLLV 650
Cdd:COG0471 327 TPPNAIVYGS----GY-YKFKDFLKVGLPLNLIGLVVLLLLGPL 365
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
173-644 |
9.26e-24 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 105.08 E-value: 9.26e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 173 VNRTFAAIIASTLSVgILAALNSRPSMATImgwiDVETLLLLFGMMILVAILSETGVFDYLA-VYAYKITNGHvwPLINC 251
Cdd:PLN00136 33 IGRTAGALLSAVLMI-VFHVISPDDAYASI----DLPILGLLFATMVVGSYLKNAGMFKHLGrLLAWRSQGGR--DLLCR 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 252 LCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIIASNSYISkngvnFAVF 331
Cdd:PLN00136 106 VCVVTALASALFTNDTCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSSATPIGNPQNLVIAFNSKIT-----FPKF 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 332 TLHMLPGVLLVMVQTYIQLRFKFrnISDLQFKDSPEVEELRHEihVWKRAAASLSAYSKDEELVRQTLMKKVNRLKRSLK 411
Cdd:PLN00136 181 LLGILPAMLAGMAVNMVMLLCMY--WKDLDGGAELSVDGKQME--AVEEGRSPASAKSTKQQSPALLQAGLNGDGNGDMS 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 412 KRMTaviepapnyqqtlANLQAKYPI------RNKPLLIKCSAALVFVISLfflhsVPELQRLSLGWTALLGAIFLIILa 485
Cdd:PLN00136 257 SMMS-------------ENISTKHPWfmqcteHRRKLFLKSFAYVVTVGMV-----VAYMVGLNMSWTAITTAIALVVV- 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 486 DIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTeGIILGVGEDRRLMVAILIILWVSAVASafvdNIPLT 565
Cdd:PLN00136 318 DFRDAEPCLDTVSYSLLVFFSGMFITVSGFNKTGLPGAIWNFM-APYSKVNSVGGISVLSVIILLLSNLAS----NVPTV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 566 TMM---VKITISLAQNSTLNLPLQPLVWAlalgACLGGNGTLIGASAN-VVC--AGVAEQHGYKFTFLQFFKVGFPimiG 639
Cdd:PLN00136 393 LLMgdeVAAAAALISPAAVTRSWLLLAWV----STVAGNLSLLGSAANlIVCeqARRAPRNAYDLTFWQHIVFGVP---S 465
|
....*
gi 442626004 640 SIIVT 644
Cdd:PLN00136 466 TLIVT 470
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
465-643 |
1.02e-18 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 88.14 E-value: 1.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 465 LQRLSLGWTALLGAIFLIILAdIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMtegIILGVGEDRRLMVA 544
Cdd:pfam03600 6 TEKLPRDVVALLGAVLLVLLG-VLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALK---LLRLAGGKPRRLLV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 545 ILIIlwVSAVASAFVDNIPLTTMMVKITISLAQnsTLNLPLQPLVWALALGACLGGNGTLIGASANVVCAGVAEQHGYKF 624
Cdd:pfam03600 82 ALML--ATALLSAFLSNDGTVLIMIPIVLALAR--RLGLPPSPLLIALAFAANIGGTATPIGDPPNIIIASALGLSFGDF 157
|
170
....*....|....*....
gi 442626004 625 TFLQFFKVGFPIMIGSIIV 643
Cdd:pfam03600 158 GFFMFPPVGVALLLVGLLP 176
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
467-650 |
5.64e-18 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 86.53 E-value: 5.64e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 467 RLSLGWTALLGAIFLIILADIeDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTegIILGVGEDRRLMVAIL 546
Cdd:cd00625 8 KLPRAVVALLGAVLLVLLGVV-SPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKL--ARASKGSRRLLLLLML 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 547 iilwVSAVASAFVDNIPLTTMMVKITISLAQNSTLNlPLQPLVWALALGACLGGNGTLIGASANVVCAGVAeqhgyKFTF 626
Cdd:cd00625 85 ----LTAALSAFFSNDATAVLLTPIVLALLRKLGLS-PPVPLLLALAFAANIGGAATPIGNPPNLIIASLS-----GLGF 154
|
170 180
....*....|....*....|....
gi 442626004 627 LQFFKVGFPIMIGSIIVTTGYLLV 650
Cdd:cd00625 155 LDFLAFMAPPALGLLLLLLGLLYL 178
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
212-649 |
2.35e-17 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 84.62 E-value: 2.35e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 212 LLLFGMMILVAILSETGVFDYLAVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNP---V 288
Cdd:cd01118 56 LTLIGVILLSLLLDEEGFFEWVAALAARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKnrtL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 289 PILMCMVIYSNIGGALTPVGDPPNVIIASNSYISkngvnFAVFTLHMLPGVLLVMVQTYIQLRFKFRnisdlqfkdspev 368
Cdd:cd01118 136 PFLYACAFIADAASLPLPISNLVNIVTAGYFGIG-----FTEYAALMFLPSIVSILATYVVLYLFFR------------- 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 369 eelrheihvwKRAAASLSAYSKDEElvrqtlmkkvnrlKRSLKKRMTAVIepapnyqqtlanlqakypirnkplliKCSA 448
Cdd:cd01118 198 ----------RALPKRLETASVKKP-------------SLAIKDPLLFGL--------------------------AWTL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 449 ALVFVISLFFLHSvpelqrLSLGWTALLGAIFLIILADIEDMEAILAR-----VEWSTLLFFAALFILMEALTELGLIEW 523
Cdd:cd01118 229 LVLLVVSAFGVDI------LLIPPSFIAGVLALIFLLLARRGGAINPLkvlkeAPWGVLLFSLGLYVVVFGLKNAGLTAI 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 524 IGNmtegiILGVGEDRRLMVAILIILWVSAVASAFVDNIPLTTMMvkiTISLAQNSTLnlplQPLVWALALGACLGGNGT 603
Cdd:cd01118 303 LAD-----LLNWLVSQGLLAAILGVGLLAAFLSNVMNNLPAVLIG---ALALAAGHAP----EALVYANLIGVDLGPKLT 370
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 442626004 604 LIGASANVVCAGVAEQHGYKFTFLQFFKVGFPIMIGSIIVTTGYLL 649
Cdd:cd01118 371 PIGSLATLLWLHVLRRKGIRVSWGYYLKVGLIVTPPVLVVTLAALI 416
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
197-650 |
3.67e-17 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 83.79 E-value: 3.67e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 197 PSMATIMGWIDVE---------TLLLLFGMMILVAILSETGVFDYLAVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVT 267
Cdd:cd01115 26 PVLLVLLGVVPPKeafsgfsdpAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAFMSNTA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 268 TVLLMTPVTIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIIASN-SYISKNGVNFAVFTLHMLPGVLLVMvqt 346
Cdd:cd01115 106 TVAIMLPVALGLAAKLDISPSRLLMPLAFAASIGGMLTLIGTPPNLVASGYlESLGGQGFSFFEFTPIGLPLLIIGL--- 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 347 yIQLRFKFRnisdlqfkdspeveelrheihvwkraaaslsayskdeelvrqtlmkkvnrlkrslkkrmTAVIepapnyqq 426
Cdd:cd01115 183 -LYLWFIFR-----------------------------------------------------------LAVL-------- 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 427 tlanlqakypirnkPLLIKCSAALVFVISLFFLHSvpelqrlslgwTALLGAIFLIILADIeDMEAILARVEWSTLLFFA 506
Cdd:cd01115 195 --------------IITIVLLAALAAITGLLPVSV-----------AIAIGAIVLVFGGVL-LTKEDYKSIDWGIIFLFA 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 507 ALFILMEALTELGLIEWIGNMtegiILGVGEDRRLMVAILIILWVSAVASAFVDNIPLTTMMVKITISLAQnsTLNLPLQ 586
Cdd:cd01115 249 GGIPLGKALESSGAAALIAEA----LISLLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIAL--SLGLPPE 322
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442626004 587 PLVWALALGACLgGNGTLIGASANVVCAGVAeqhgyKFTFLQFFKVGFPIMIGSIIVTTGYLLV 650
Cdd:cd01115 323 ALLLAVAIGASC-AFMLPVGTPPNAIVLGPG-----GYKFSDFAKVGLPLSILSLVVSVTMIPL 380
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
448-638 |
9.74e-15 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 76.47 E-value: 9.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 448 AALVFVISLFFLHSVPelqrlsLGWTALLgAIFLIILADIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNM 527
Cdd:cd01115 2 AILVFAAVLFVTEALP------LDVTALL-VPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 528 tegIILGVGEDRRLMVAILIIlwVSAVASAFVDNIPLTTMMVKITISLAqnSTLNLPLQPLVWALALGACLGGNGTLIGA 607
Cdd:cd01115 75 ---LLKRAGKGERRLLLLLML--VTAFLSAFMSNTATVAIMLPVALGLA--AKLDISPSRLLMPLAFAASIGGMLTLIGT 147
|
170 180 190
....*....|....*....|....*....|..
gi 442626004 608 SANVVCAGVAEQHGYK-FTFLQFFKVGFPIMI 638
Cdd:cd01115 148 PPNLVASGYLESLGGQgFSFFEFTPIGLPLLI 179
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
129-350 |
1.85e-14 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 75.75 E-value: 1.85e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 129 FTSSIEGELPLQLNVDESPIYKRDGVIYAAAVLCGLYVMIIWEIVNRTFAAIIASTLSVGILAALNSRPSMATIMGWIDV 208
Cdd:cd00625 180 FRKKLLLPDEDKLTVLAEPLPARPLLKKFLLLALLLLLLFVLLFFFLIPLGLIALLGALLLLLLLVRGLDPEEVLKSVDW 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 209 ETLLLLFGMMILVAILSETGVFDYLAVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLcevmcLNPV 288
Cdd:cd00625 260 GTLLFFAGLFVLVGALESTGLLEWLAELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASL-----APPE 334
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442626004 289 PILMCMVIYSNIGGALTPVGDPPNVIIASNSYISKNGVNFAVFTLHMLPGVLLVMVQTYIQL 350
Cdd:cd00625 335 PAWLALALGSTLGGNLTLIGSLANLIPLGAAENAGVGISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
474-652 |
1.00e-11 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 67.28 E-value: 1.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 474 ALLGAIFLIIL---ADIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTegIILGVGEDRRLMvaILIILw 550
Cdd:cd01116 19 ALAGALWLVILglaTLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWA--VKISKGRPWRLL--LLLGL- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 551 VSAVASAFVDNIPLTTMMVKITISLAQnsTLNLPLQPLVWALALGACLGGNGTLIGASANVVCAGVAeqhgyKFTFLQFF 630
Cdd:cd01116 94 LTAFLSAFLDNVTTVLLMVPVTIRLCE--VLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIGSAA-----GLTFNDFL 166
|
170 180
....*....|....*....|..
gi 442626004 631 KVGFPIMIGSIIVTTGYLLVSH 652
Cdd:cd01116 167 LHMLPSVVLALVVTFILLYFLY 188
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
206-322 |
1.23e-11 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 66.72 E-value: 1.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 206 IDVETLLLLFGMMILVAILSETGVFDYLAVYAYKITNG-HVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMC 284
Cdd:COG0471 224 IPWGVLLLFGGGLALGAALEKTGLAAWLADALLPLLGGlSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALG 303
|
90 100 110
....*....|....*....|....*....|....*...
gi 442626004 285 LNPVPILMCMVIySNIGGALTPVGDPPNVIIASNSYIS 322
Cdd:COG0471 304 VNPLPLALAVAF-AASCAFLLPVGTPPNAIVYGSGYYK 340
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
159-647 |
1.63e-11 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 66.98 E-value: 1.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 159 AVLCGLYVMIIWEIVNRTFAAIIASTLSVGILAALNSRPSMATIMGWIDvETLLLLFGMMILVAILSETGVFDYLAvyaY 238
Cdd:TIGR00785 15 AIFVAAIVGWILEPLPLPVTALLAIPIIAVLLGVLSAFKFKNALSGFAD-PTIWLFFGAFILATALVKTGLGKRIA---Y 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 239 KITN--GHVWPLINCLCLF-TAVLSSFLDNVT--TVLLMTPVTIRLCEVMCLNPVPI-------LMCMVIYS-NIGGALT 305
Cdd:TIGR00785 91 KLVGkmGGTTLGLGYFLVFlETLLAPMWPSNTarAGGILLPIIKSLLPLLGSKPEKSprkigkyLMLGIAYSaSIGSSGF 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 306 PVGDPPNVIIASN-SYISKNGVNFAVFTLHMLP-GVLLVMVQTYiqlrfkfrnisdLQFKDSPEVEELRHEIHVWKRaaa 383
Cdd:TIGR00785 171 LTGSAPNALAAGIlSKILGIQISWGDWFLAGLPlGIILLLLVPL------------LLYVLFPPELKLKDEVDLWAK--- 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 384 slsayskdEELVRQTLMkkvnrlkrSLKKRMTAVIepapnyqqtlanlqakypirnkpllikCSAALVFVISLFFLHsvp 463
Cdd:TIGR00785 236 --------EELEEMGPM--------SFREKALLGI---------------------------FLLALLLWIFGGSLG--- 269
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 464 elqrLSLGWTALLGAIFLIILADIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGIILGVGEdrrLMV 543
Cdd:TIGR00785 270 ----INASVVALLAVVLMLFLGIVTWKDIQKNKVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSP---TIA 342
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 544 AILIILWVSAVASAFVDNIPLTTMMVKITISLAQnsTLNLPLQPLVWALALGACLGGNGTLIGASANVVCAGVaeqhGYk 623
Cdd:TIGR00785 343 VLVLVVLFYIILYFFASNTAHTAALVPIFFSVAS--AQGIPLELLALALALSASLMGFLTPYATPPNAIAYGS----GY- 415
|
490 500
....*....|....*....|....
gi 442626004 624 FTFLQFFKVGFPIMIGSIIVTTGY 647
Cdd:TIGR00785 416 VKIKDMWRVGAIIGIVGLIVLLLV 439
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
153-322 |
2.00e-10 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 62.99 E-value: 2.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 153 GVIYAAAVLCGLYVMIIWEIVNRTFAAIIASTLSVGILAA-----LNSRPSMATIMGWIDVETLLLLFGMMILVAILSET 227
Cdd:cd01115 181 GLLYLWFIFRLAVLIITIVLLAALAAITGLLPVSVAIAIGaivlvFGGVLLTKEDYKSIDWGIIFLFAGGIPLGKALESS 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 228 GVFDYLAVY-AYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNPVPILMCMVIYSNIgGALTP 306
Cdd:cd01115 261 GAAALIAEAlISLLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASC-AFMLP 339
|
170
....*....|....*.
gi 442626004 307 VGDPPNVIIASNSYIS 322
Cdd:cd01115 340 VGTPPNAIVLGPGGYK 355
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
136-296 |
5.98e-09 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 58.09 E-value: 5.98e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 136 ELPLQLNVDESPIYKRDGVIYAAAVLCGLYVMIIWEIVNrtFAAIIASTLSVGILAALNSRPSMATIMGWIDVETLLLLF 215
Cdd:pfam03600 184 LLPVRKEEEAELEELRKRAIKDKLLLAISALVLALVILG--FLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTLLFFA 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 216 GMMILVAILSETGVFDYLAVYAYKITNGHVwpLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVM-CLNPVPILMCM 294
Cdd:pfam03600 262 GLFILVGALEKTGLADALADALGGLSGLLV--ALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAgLGDPDPLAWAL 339
|
..
gi 442626004 295 VI 296
Cdd:pfam03600 340 AV 341
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
449-643 |
6.25e-08 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 55.46 E-value: 6.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 449 ALVFVISLFFLHSVPELQrLSLGWTALLGAIFLIILaDIEDMEAILA-RVEWSTLLFFAALFILMEALTELGLIEWIGNM 527
Cdd:pfam00939 273 LGLFVLLLLLWIFGGSLN-IDATTVAIIGLALMLLL-RILDWKDIVKnKGAWNTLIWLGGLIMLANGLERSGFIEWLGNT 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 528 TEGIIlgvgEDRRLMVAILIILWVS-AVASAFVDNIPLTTMMVKITISLAQNSTLNLPLQpLVWALALGACLGGNGTLIG 606
Cdd:pfam00939 351 LSTSL----SGFSPAMAFIIILSLFyLSHYLFASATAHTAAMLPIFAAVAQAIPGAPPLL-AALLLGFAISLGGFLTPYG 425
|
170 180 190
....*....|....*....|....*....|....*..
gi 442626004 607 ASANVVCAGVaeqhGYkFTFLQFFKVGFPIMIGSIIV 643
Cdd:pfam00939 426 TGPGPIYFGS----GY-LKVKDWWRIGAILTIIGLLI 457
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
448-650 |
4.25e-07 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 52.73 E-value: 4.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 448 AALVFVISLFFLHSVPelqrlsLGWTALLGAIFLIILADIEDMEAILARVEW----STLLFFAAlFILMEALTELGLIEW 523
Cdd:TIGR00785 15 AIFVAAIVGWILEPLP------LPVTALLAIPIIAVLLGVLSAFKFKNALSGfadpTIWLFFGA-FILATALVKTGLGKR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 524 IGNmtegIILGVGEDRRLMVAILIILWVSAVASAFVDNIPLTTMMVkitISLAQNSTLNLPLQP----------LVWALA 593
Cdd:TIGR00785 88 IAY----KLVGKMGGTTLGLGYFLVFLETLLAPMWPSNTARAGGIL---LPIIKSLLPLLGSKPeksprkigkyLMLGIA 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 442626004 594 LGACLGGNGTLIGASANVVCAG-VAEQHGYKFTFLQFFKVGFPIMIGSIIVTTGYLLV 650
Cdd:TIGR00785 161 YSASIGSSGFLTGSAPNALAAGiLSKILGIQISWGDWFLAGLPLGIILLLLVPLLLYV 218
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
456-649 |
4.40e-07 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 52.69 E-value: 4.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 456 LFFLHSV-PELQRLSLGWTA--LLGAIFLIILADIEDMEAiLARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGII 532
Cdd:PLN00136 18 VFWMLAVfPSVPFLPIGRTAgaLLSAVLMIVFHVISPDDA-YASIDLPILGLLFATMVVGSYLKNAGMFKHLGRLLAWRS 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 533 LGvgeDRRLMVAILIilwVSAVASAFVDNIPLTTMMVKITISLAQNStlNLPLQPLVWALALGACLGGNGTLIGASANVV 612
Cdd:PLN00136 97 QG---GRDLLCRVCV---VTALASALFTNDTCCVVLTEFVLELAAER--NLPAKPFLLALASSANIGSSATPIGNPQNLV 168
|
170 180 190
....*....|....*....|....*....|....*..
gi 442626004 613 CAgvaeqHGYKFTFLQFFKVGFPIMIGSIIVTTGYLL 649
Cdd:PLN00136 169 IA-----FNSKITFPKFLLGILPAMLAGMAVNMVMLL 200
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
448-648 |
2.14e-05 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 47.26 E-value: 2.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 448 AALVFVISLFFLHSVPelQRLSLGWTALLGAIFLIIL-----ADIEDMEAILarveWSTLLFFAALFILMEALTELGLIE 522
Cdd:cd01118 2 AIAIFVLTLVLVIWRP--FGLPEAVWAVLGAVIALILglvspHDALEVWGIV----WDVTLTLIGVILLSLLLDEEGFFE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 523 WIGNMTegIILGVGEDRRLMVAILIilwVSAVASAFVDNIplTTMMVKITISLAQNSTLNL---PLQPLVWALALGACLG 599
Cdd:cd01118 76 WVAALA--ARWARGSGRKLFTLIVL---LGAAVTAFFAND--GTALILTPIVIALLRALGAkknRTLPFLYACAFIADAA 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 442626004 600 GNGTLIGASANVVCAGvaeqhGYKFTFLQFFKVGFPIMIGSIIVTTGYL 648
Cdd:cd01118 149 SLPLPISNLVNIVTAG-----YFGIGFTEYAALMFLPSIVSILATYVVL 192
|
|
| PLN00137 |
PLN00137 |
NHAD transporter family protein; Provisional |
208-652 |
4.10e-05 |
|
NHAD transporter family protein; Provisional
Pssm-ID: 215071 Cd Length: 424 Bit Score: 46.61 E-value: 4.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 208 VETLLLLFGMMILVAILSETGVFDylaVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEvmclNP 287
Cdd:PLN00137 66 SEIVFFLLGAMTIVEIVDAHQGFK---LVTDSITTRSPRTLLWVVGFITFFLSSILDNLTTTIVMVSLLRKLVP----PS 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 288 VPILMC---MVIYSNIGGALTPVGDPPNVIIASNSYISkngvnfavfTLHMLPGVLLvmvqtyiqlrfkfrnisdlqfkd 364
Cdd:PLN00137 139 EYRKLLgavVVVAANAGGAWTPIGDVTTTMLWIHGQIS---------TLPTMQGLFL----------------------- 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 365 sPEVEELrheihvwkraAASLSAYSkdeelvrqtLMKKVNRLKRSLKKRMTAViEPAPNYQQTLAnlqakypirnkplli 444
Cdd:PLN00137 187 -PSAVSL----------AVPLALMS---------LTSEENGSPQDSSPLLASE-QMAPRGQLVFG--------------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 445 kcsaalVFVISLFFLHSVPELQRLSLGWTALLGAIFLIILADIE----------DMEAILARVEWSTLLFFAALFILMEA 514
Cdd:PLN00137 231 ------VGVGALLFVPVFKALTGLPPYMGMLLGLGVLWILTDAIhygeserqalKVPQALSRIDTQGILFFLGILLSVGS 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 515 LTELGLIEWIGNMTEGIILGVGedrrlmvailIILWVSAVASAFVDNIPLT--TMMVKITISLAQNSTLnlplqplvWAL 592
Cdd:PLN00137 305 LDAAGILRELANYLDANIPNVE----------LIASAIGVASAIIDNVPLVaaTMGMYDLTDYPMDSEL--------WQL 366
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442626004 593 -ALGACLGGNGTLIGASANVVCAGVAEqhgyKFTFLQFFKVGFPIMIGSIIVTTGYLLVSH 652
Cdd:PLN00137 367 iALCAGTGGSLLVIGSAAGVAFMGMEK----VDFFWYLRKVSGFAFAGYVAGIAAYLAVNG 423
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
161-322 |
5.47e-05 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 46.21 E-value: 5.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 161 LCGLYVMIIWEIVNRTFAAIIASTLSVGILAALnsrpSMATIMGWIDV-------ETLLLLFGMMILVAILSETGVFDYL 233
Cdd:pfam00939 272 LLGLFVLLLLLWIFGGSLNIDATTVAIIGLALM----LLLRILDWKDIvknkgawNTLIWLGGLIMLANGLERSGFIEWL 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 234 AVYAYKITNGHVWPL--INCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNPVPILMCMVIYS-NIGGALTPVGDP 310
Cdd:pfam00939 348 GNTLSTSLSGFSPAMafIIILSLFYLSHYLFASATAHTAAMLPIFAAVAQAIPGAPPLLAALLLGFAiSLGGFLTPYGTG 427
|
170
....*....|..
gi 442626004 311 PNVIIASNSYIS 322
Cdd:pfam00939 428 PGPIYFGSGYLK 439
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
150-350 |
5.52e-05 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 46.12 E-value: 5.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 150 KRDGVIYAAAVLCGLYVMI--IWEIVNRTFAAIIASTLsvgilaALNSRPSMATIMGWIDVETLLLLFGMMILVAILSET 227
Cdd:cd01117 201 ARKLAVKLLVLILLLLVAFlaLLGVIPLWTAALVAAVL------LLLTRLKPRRVLKKVDWGLLLFFAGLFILVGGFAQG 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 228 GVFDYLAVYAykITNGHVWPLInclcLFTAVLSSFLDNVTTVLLMTPVTIRLcevmclnPVPILMCMVIYSNIGGALTPV 307
Cdd:cd01117 275 LPLEGLSRLL--PLLDSVLSLF----LVSIGLSQLISNVPAVLLLLPFLPSA-------DEKDWLLLAAGSTIAGNLTLL 341
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 442626004 308 GDPPNVIIASNSYISKNGVNFAVFTLHMLPGVLLVMVQTYIQL 350
Cdd:cd01117 342 GSAANLIVAEAAERRGVRLSFGEFLKYGVPLTLLTAAIGILWL 384
|
|
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
474-655 |
8.94e-04 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 42.08 E-value: 8.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 474 ALLGAIFLIILA---DIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGIIlgvgeDRRLMVAILIILW 550
Cdd:PRK15445 251 AGVGALILLLVArrgHAINTKKVLKGAPWQIVIFSLGMYLVVYGLRNAGLTDYLAGVLNYLA-----DQGLFAATLGTGF 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 551 VSAVASAFVDNIPlTTMMVKITISLAQNSTLnlPLQPLVWALALGACLGGNGTLIGASANVVCAGVAEQHGYKFTFLQFF 630
Cdd:PRK15445 326 LAAFLSSVMNNMP-TVLIGALAIDGSNATGV--IKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGYYF 402
|
170 180
....*....|....*....|....*
gi 442626004 631 KVGFPIMIGSIIVTTGYLLVSHSLF 655
Cdd:PRK15445 403 KVGIIITLPVLLVTLLALALRLSLF 427
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
211-308 |
9.79e-04 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 41.87 E-value: 9.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 211 LLLLFGMMILVAILSETGVFDYLAVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLcevmcLNPVPI 290
Cdd:cd01118 281 LLFSLGLYVVVFGLKNAGLTAILADLLNWLVSQGLLAAILGVGLLAAFLSNVMNNLPAVLIGALALAAG-----HAPEAL 355
|
90
....*....|....*...
gi 442626004 291 LMCMVIYSNIGGALTPVG 308
Cdd:cd01118 356 VYANLIGVDLGPKLTPIG 373
|
|
| CitMHS_2 |
pfam16980 |
Putative citrate transport; CitMHS is a family of putative citrate transporters, belonging to ... |
211-344 |
7.00e-03 |
|
Putative citrate transport; CitMHS is a family of putative citrate transporters, belonging to the Na+/H+ antiporter NhaD-like permease superfamily.
Pssm-ID: 465328 Cd Length: 440 Bit Score: 39.50 E-value: 7.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 211 LLLLFGMMILVAILSETGVFDYLA----VYA-YKITNG-HVW------PLINCLCLFT-AVLSSFLDnvTT---VLLMTP 274
Cdd:pfam16980 49 FAALFGVGAAGAELLHTLLLEYIPfiilLFAlFTVAGGiLIRgnlagtPLVNTLLLAIgTVLASWIG--TTgasMLLIRP 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 275 VtIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIiasnSYIskNGVNFAVFTLHMLPGVLLVMV 344
Cdd:pfam16980 127 L-IRANDWRKHKVHVVVFFIFLVSNIGGSLTPLGDPPLFL----GFL--KGVPFFWTTRHLLPETLFAVG 189
|
|
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
448-561 |
9.03e-03 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 39.00 E-value: 9.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442626004 448 AALVFVISLFFLHSVPelQRLSLGWTALLGAIFLII-----LADIEDMEAILarveWSTLLFFAALFILMEALTELGLIE 522
Cdd:PRK15445 3 AIAIFLLTLVLVIWQP--KGLGIGWSALLGAVLALLtgvvsLGDVPVVWGIV----WNATLTFIAIIIISLLLDEAGFFE 76
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 442626004 523 WIG-NMtegIILGVGEDRRLMVAILIIlwvSAVASAFVDN 561
Cdd:PRK15445 77 WAAlHV---ARWAKGNGRKLFVYIVLL---GAAVAALFAN 110
|
|
| |
