NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|409971436|ref|NP_001258501|]
View 

peroxisomal membrane protein 11A isoform 2 [Homo sapiens]

Protein Classification

PEX11 family protein( domain architecture ID 10529115)

peroxin-11 (PEX11) family protein is a membrane elongation factor that coordinates peroxisome proliferation and maintenance

Gene Ontology:  GO:0005778|GO:0016559
PubMed:  20826455|16978390

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PEX11 pfam05648
Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal ...
1-206 1.14e-62

Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal biogenesis factor 11 (PEX11) proteins from several eukaryotic species. The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple eukaryotes.


:

Pssm-ID: 398979  Cd Length: 223  Bit Score: 194.41  E-value: 1.14e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409971436    1 MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRK----------------------- 57
Cdd:pfam05648   1 LDHLVRFLASTVGRDKLLRTLQYASRLLAYYLERKGSSPELVDKLKNLESQFSLSRKllrlgkflnhlqaaakyydnklp 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409971436   58 ----------SNLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRV-TCDRAKKE 126
Cdd:pfam05648  81 dpvlrllavlRNLGYALYLFLDHVLWLARTGLLKVKNAKRWSRISSRFWLFGLVLSLVRDLYELRRLQEKEaSLRKEKKE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409971436  127 KSASQDPlwfsvaeeetewlqsfllLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITV 206
Cdd:pfam05648 161 KESNEER------------------KLAAVLKKRPAALLDLVKNLCDLFIALNLLGILRFNDGVVGLAGLISSLIGLYQL 222
 
Name Accession Description Interval E-value
PEX11 pfam05648
Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal ...
1-206 1.14e-62

Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal biogenesis factor 11 (PEX11) proteins from several eukaryotic species. The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple eukaryotes.


Pssm-ID: 398979  Cd Length: 223  Bit Score: 194.41  E-value: 1.14e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409971436    1 MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRK----------------------- 57
Cdd:pfam05648   1 LDHLVRFLASTVGRDKLLRTLQYASRLLAYYLERKGSSPELVDKLKNLESQFSLSRKllrlgkflnhlqaaakyydnklp 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409971436   58 ----------SNLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRV-TCDRAKKE 126
Cdd:pfam05648  81 dpvlrllavlRNLGYALYLFLDHVLWLARTGLLKVKNAKRWSRISSRFWLFGLVLSLVRDLYELRRLQEKEaSLRKEKKE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409971436  127 KSASQDPlwfsvaeeetewlqsfllLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITV 206
Cdd:pfam05648 161 KESNEER------------------KLAAVLKKRPAALLDLVKNLCDLFIALNLLGILRFNDGVVGLAGLISSLIGLYQL 222
 
Name Accession Description Interval E-value
PEX11 pfam05648
Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal ...
1-206 1.14e-62

Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal biogenesis factor 11 (PEX11) proteins from several eukaryotic species. The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple eukaryotes.


Pssm-ID: 398979  Cd Length: 223  Bit Score: 194.41  E-value: 1.14e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409971436    1 MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRK----------------------- 57
Cdd:pfam05648   1 LDHLVRFLASTVGRDKLLRTLQYASRLLAYYLERKGSSPELVDKLKNLESQFSLSRKllrlgkflnhlqaaakyydnklp 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409971436   58 ----------SNLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRV-TCDRAKKE 126
Cdd:pfam05648  81 dpvlrllavlRNLGYALYLFLDHVLWLARTGLLKVKNAKRWSRISSRFWLFGLVLSLVRDLYELRRLQEKEaSLRKEKKE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409971436  127 KSASQDPlwfsvaeeetewlqsfllLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITV 206
Cdd:pfam05648 161 KESNEER------------------KLAAVLKKRPAALLDLVKNLCDLFIALNLLGILRFNDGVVGLAGLISSLIGLYQL 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH