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Conserved domains on  [gi|392921798|ref|NP_001256573|]
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DUF148 domain-containing protein [Caenorhabditis elegans]

Protein Classification

DUF4473 domain-containing protein( domain architecture ID 10631710)

DUF4473 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF4473 pfam14747
Domain of unknown function (DUF4473); This short family is largely confined to Caenorhabditis ...
23-99 8.98e-26

Domain of unknown function (DUF4473); This short family is largely confined to Caenorhabditis proteins. The function is not known. There are two well-conserved aspartate residues.


:

Pssm-ID: 373266  Cd Length: 78  Bit Score: 91.13  E-value: 8.98e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392921798   23 PSQEQYNAELKSAGMSQAGIDGLNVLSQKFVSQYPVVQANKEAADKFLAEYTEEAQNYVKSMSPEDQKIYAESLKKY 99
Cdd:pfam14747   2 PTAEEAKAELVAAGMSEKAADGLVKIAEKFKSEFPKAKGDKEAAKKAFEKYKAETDAFIKTQSEEDQTAYKAFVEKK 78
 
Name Accession Description Interval E-value
DUF4473 pfam14747
Domain of unknown function (DUF4473); This short family is largely confined to Caenorhabditis ...
23-99 8.98e-26

Domain of unknown function (DUF4473); This short family is largely confined to Caenorhabditis proteins. The function is not known. There are two well-conserved aspartate residues.


Pssm-ID: 373266  Cd Length: 78  Bit Score: 91.13  E-value: 8.98e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392921798   23 PSQEQYNAELKSAGMSQAGIDGLNVLSQKFVSQYPVVQANKEAADKFLAEYTEEAQNYVKSMSPEDQKIYAESLKKY 99
Cdd:pfam14747   2 PTAEEAKAELVAAGMSEKAADGLVKIAEKFKSEFPKAKGDKEAAKKAFEKYKAETDAFIKTQSEEDQTAYKAFVEKK 78
HMG-box_UBF1_rpt6-like cd22003
sixth high mobility group (HMG)-box found in upstream-binding factor 1 (UBF1) and similar ...
63-96 6.77e-03

sixth high mobility group (HMG)-box found in upstream-binding factor 1 (UBF1) and similar proteins; UBF1, also called UBTF, nucleolar transcription factor 1, or auto-antigen NOR-90, is a nucleolar transcription factor that recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. UBF1 contains six HMG-box domains. This model corresponds to the sixth one. This model also includes the second HMG-box domain of upstream-binding factor 1-like protein 1 (UBTFL1), which contains two HMG-box domains.


Pssm-ID: 438819 [Multi-domain]  Cd Length: 86  Bit Score: 33.04  E-value: 6.77e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 392921798  63 KEAADKFLAEYTEEAQNYVKSMSPEDQKIYAESL 96
Cdd:cd22003   52 KKKAEELQKQYKKKLDKYLKSLSPEERAAYEEYS 85
 
Name Accession Description Interval E-value
DUF4473 pfam14747
Domain of unknown function (DUF4473); This short family is largely confined to Caenorhabditis ...
23-99 8.98e-26

Domain of unknown function (DUF4473); This short family is largely confined to Caenorhabditis proteins. The function is not known. There are two well-conserved aspartate residues.


Pssm-ID: 373266  Cd Length: 78  Bit Score: 91.13  E-value: 8.98e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392921798   23 PSQEQYNAELKSAGMSQAGIDGLNVLSQKFVSQYPVVQANKEAADKFLAEYTEEAQNYVKSMSPEDQKIYAESLKKY 99
Cdd:pfam14747   2 PTAEEAKAELVAAGMSEKAADGLVKIAEKFKSEFPKAKGDKEAAKKAFEKYKAETDAFIKTQSEEDQTAYKAFVEKK 78
HMG-box_UBF1_rpt6-like cd22003
sixth high mobility group (HMG)-box found in upstream-binding factor 1 (UBF1) and similar ...
63-96 6.77e-03

sixth high mobility group (HMG)-box found in upstream-binding factor 1 (UBF1) and similar proteins; UBF1, also called UBTF, nucleolar transcription factor 1, or auto-antigen NOR-90, is a nucleolar transcription factor that recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. UBF1 contains six HMG-box domains. This model corresponds to the sixth one. This model also includes the second HMG-box domain of upstream-binding factor 1-like protein 1 (UBTFL1), which contains two HMG-box domains.


Pssm-ID: 438819 [Multi-domain]  Cd Length: 86  Bit Score: 33.04  E-value: 6.77e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 392921798  63 KEAADKFLAEYTEEAQNYVKSMSPEDQKIYAESL 96
Cdd:cd22003   52 KKKAEELQKQYKKKLDKYLKSLSPEERAAYEEYS 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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