Vacuolar protein sorting-associated protein 54 [Caenorhabditis elegans]
vacuolar protein sorting-associated protein 54( domain architecture ID 10996507)
vacuolar protein sorting-associated protein 54 is a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network
List of domain hits
Name | Accession | Description | Interval | E-value | |||
Vps54 | pfam07928 | Vps54-like protein; This family contains various proteins that are homologs of the yeast Vps54 ... |
510-638 | 1.89e-49 | |||
Vps54-like protein; This family contains various proteins that are homologs of the yeast Vps54 protein, such as the rat homolog, the human homolog, and the mouse homolog. In yeast, Vps54 associates with Vps52 and Vps53 proteins to form a trimolecular complex that is involved in protein transport between Golgi, endosomal, and vacuolar compartments. All Vps54 homologs contain a coiled coil region (not found in the region featured in this family) and multiple dileucine motifs. : Pssm-ID: 462318 Cd Length: 131 Bit Score: 169.62 E-value: 1.89e-49
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COG2 super family | cl19297 | COG (conserved oligomeric Golgi) complex component, COG2; The COG complex comprises eight ... |
3-140 | 3.82e-04 | |||
COG (conserved oligomeric Golgi) complex component, COG2; The COG complex comprises eight proteins COG1-8. The COG complex plays critical roles in Golgi structure and function. The proposed function of the complex is to mediate the initial physical contact between transport vesicles and their membrane targets. A comparable role in tethering vesicles has been suggested for at least six additional large multisubunit complexes, including the exocyst, a complex that mediates trafficking to the plasma membrane. COG2 structure reveals a six-helix bundle with few conserved surface features but a general resemblance to recently determined crystal structures of four different exocyst subunits. These bundles inCOG2 may act as platforms for interaction with other trafficing proteins including SNAREs (soluble N-ethylmaleimide factor attachment protein receptors) and Rabs. The actual alignment was detected with superfamily member pfam10475: Pssm-ID: 473160 Cd Length: 291 Bit Score: 43.11 E-value: 3.82e-04
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Name | Accession | Description | Interval | E-value | |||
Vps54 | pfam07928 | Vps54-like protein; This family contains various proteins that are homologs of the yeast Vps54 ... |
510-638 | 1.89e-49 | |||
Vps54-like protein; This family contains various proteins that are homologs of the yeast Vps54 protein, such as the rat homolog, the human homolog, and the mouse homolog. In yeast, Vps54 associates with Vps52 and Vps53 proteins to form a trimolecular complex that is involved in protein transport between Golgi, endosomal, and vacuolar compartments. All Vps54 homologs contain a coiled coil region (not found in the region featured in this family) and multiple dileucine motifs. Pssm-ID: 462318 Cd Length: 131 Bit Score: 169.62 E-value: 1.89e-49
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Vps54_N | pfam10475 | Vacuolar-sorting protein 54, of GARP complex; This is a family of vacuolar-sorting proteins 54, ... |
3-140 | 3.82e-04 | |||
Vacuolar-sorting protein 54, of GARP complex; This is a family of vacuolar-sorting proteins 54, from eukaryotes. Along with VPS52 and VPS53 this forms the Golgi-associated retrograde protein complex GARP. VPS54 is separated into N- and C-terminal regions each of which has a different function. This N-terminal family of is important for GARP complex assembly and stability, whereas the C-terminal domain, pfam07928, brings about localization to an early endocytic compartment. Pssm-ID: 431303 Cd Length: 291 Bit Score: 43.11 E-value: 3.82e-04
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Name | Accession | Description | Interval | E-value | |||
Vps54 | pfam07928 | Vps54-like protein; This family contains various proteins that are homologs of the yeast Vps54 ... |
510-638 | 1.89e-49 | |||
Vps54-like protein; This family contains various proteins that are homologs of the yeast Vps54 protein, such as the rat homolog, the human homolog, and the mouse homolog. In yeast, Vps54 associates with Vps52 and Vps53 proteins to form a trimolecular complex that is involved in protein transport between Golgi, endosomal, and vacuolar compartments. All Vps54 homologs contain a coiled coil region (not found in the region featured in this family) and multiple dileucine motifs. Pssm-ID: 462318 Cd Length: 131 Bit Score: 169.62 E-value: 1.89e-49
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Vps54_N | pfam10475 | Vacuolar-sorting protein 54, of GARP complex; This is a family of vacuolar-sorting proteins 54, ... |
3-140 | 3.82e-04 | |||
Vacuolar-sorting protein 54, of GARP complex; This is a family of vacuolar-sorting proteins 54, from eukaryotes. Along with VPS52 and VPS53 this forms the Golgi-associated retrograde protein complex GARP. VPS54 is separated into N- and C-terminal regions each of which has a different function. This N-terminal family of is important for GARP complex assembly and stability, whereas the C-terminal domain, pfam07928, brings about localization to an early endocytic compartment. Pssm-ID: 431303 Cd Length: 291 Bit Score: 43.11 E-value: 3.82e-04
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Blast search parameters | ||||
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