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Conserved domains on  [gi|392892361|ref|NP_001254409|]
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Rubicon Homology domain-containing protein [Caenorhabditis elegans]

Protein Classification

zf-RING_9 domain-containing protein( domain architecture ID 10621367)

zf-RING_9 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-RING_9 pfam13901
Putative zinc-RING and/or ribbon; This is a family of cysteine-rich proteins. Many members ...
 260-460 5.40e-78

Putative zinc-RING and/or ribbon; This is a family of cysteine-rich proteins. Many members also carry a pleckstrin-homology domain, pfam00169


:

Pssm-ID: 464030  Cd Length: 205  Bit Score: 242.14  E-value: 5.40e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392892361  260 CAIDSKYYCTECMkSGGKVSIPARVVMDWDWRERAVSDRGRAWYEANQEKALINIKTTNSRLYAHAPALEETRKLREKLQ 339
Cdd:pfam13901   3 CDYTGKYYCSGCH-WNDTSVIPARILHNWDFKKYPVSKFAKQLLDSIYSQPLLNLSDLNPSLYSKVKELAKVRELREQLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392892361  340 LVSMYLFTCRESVSEDFRR--RLWPKEYLRSEIDVYSFADLIDVKSGALQRRLNSLLKHSINHVMTCTLCKQKGFCCELC 417
Cdd:pfam13901  82 LLKDYLKTCRFAAEEELLKlfRLRPRHHLLEDSHLYSLQDLVDIKNGSLLPFLEELVQFAEKHVTNCELCQGKGFICELC 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 392892361  418 TVNEVIYPFNTESTHRCLVCFSAFHVECWR-TSGDCPKCVRRQN 460
Cdd:pfam13901 162 NSDDIIFPFDIDTTSRCEKCKAVFHKSCFRsGASPCPKCERLQK 205
 
Name Accession Description Interval E-value
zf-RING_9 pfam13901
Putative zinc-RING and/or ribbon; This is a family of cysteine-rich proteins. Many members ...
 260-460 5.40e-78

Putative zinc-RING and/or ribbon; This is a family of cysteine-rich proteins. Many members also carry a pleckstrin-homology domain, pfam00169


Pssm-ID: 464030  Cd Length: 205  Bit Score: 242.14  E-value: 5.40e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392892361  260 CAIDSKYYCTECMkSGGKVSIPARVVMDWDWRERAVSDRGRAWYEANQEKALINIKTTNSRLYAHAPALEETRKLREKLQ 339
Cdd:pfam13901   3 CDYTGKYYCSGCH-WNDTSVIPARILHNWDFKKYPVSKFAKQLLDSIYSQPLLNLSDLNPSLYSKVKELAKVRELREQLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392892361  340 LVSMYLFTCRESVSEDFRR--RLWPKEYLRSEIDVYSFADLIDVKSGALQRRLNSLLKHSINHVMTCTLCKQKGFCCELC 417
Cdd:pfam13901  82 LLKDYLKTCRFAAEEELLKlfRLRPRHHLLEDSHLYSLQDLVDIKNGSLLPFLEELVQFAEKHVTNCELCQGKGFICELC 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 392892361  418 TVNEVIYPFNTESTHRCLVCFSAFHVECWR-TSGDCPKCVRRQN 460
Cdd:pfam13901 162 NSDDIIFPFDIDTTSRCEKCKAVFHKSCFRsGASPCPKCERLQK 205
RING-HC_PCGF5 cd16737
RING finger found in polycomb group RING finger protein 5 (PCGF5) and similar proteins; PCGF5, ...
 399-455 6.31e-03

RING finger found in polycomb group RING finger protein 5 (PCGF5) and similar proteins; PCGF5, also known as RING finger protein 159 (RNF159), is one of six PcG RING finger (PCGF) homologs (PCGF1/NSPc1, PCGF2/Mel-18, PCGF3, PCGF4/BMI1, PCGF5, and PCGF6/MBLR) and serves as the core component of a Polycomb repressive complex 1 (PRC1). Like other PCGF homologs, PCGF5 associates with ring finger protein 2 (RNF2) to form a RNF2-PCGF heterodimer, which is catalytically competent as an E3 ubiquitin transferase and is the scaffold for the assembly of additional components. PCGF5 contains a C3HC4-type RING-HC finger.


Pssm-ID: 438395 [Multi-domain]  Cd Length: 95  Bit Score: 36.27  E-value: 6.31e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 392892361 399 NHVMTCTLCkqKGFCCELCTVNEVIYPFntesthrCLVCFsafhVECWRTSGDCPKC 455
Cdd:cd16737    8 NPYITCRIC--KGYLIKPTTVTECLHTF-------CKSCI----VQHFEDSNDCPEC 51
 
Name Accession Description Interval E-value
zf-RING_9 pfam13901
Putative zinc-RING and/or ribbon; This is a family of cysteine-rich proteins. Many members ...
 260-460 5.40e-78

Putative zinc-RING and/or ribbon; This is a family of cysteine-rich proteins. Many members also carry a pleckstrin-homology domain, pfam00169


Pssm-ID: 464030  Cd Length: 205  Bit Score: 242.14  E-value: 5.40e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392892361  260 CAIDSKYYCTECMkSGGKVSIPARVVMDWDWRERAVSDRGRAWYEANQEKALINIKTTNSRLYAHAPALEETRKLREKLQ 339
Cdd:pfam13901   3 CDYTGKYYCSGCH-WNDTSVIPARILHNWDFKKYPVSKFAKQLLDSIYSQPLLNLSDLNPSLYSKVKELAKVRELREQLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392892361  340 LVSMYLFTCRESVSEDFRR--RLWPKEYLRSEIDVYSFADLIDVKSGALQRRLNSLLKHSINHVMTCTLCKQKGFCCELC 417
Cdd:pfam13901  82 LLKDYLKTCRFAAEEELLKlfRLRPRHHLLEDSHLYSLQDLVDIKNGSLLPFLEELVQFAEKHVTNCELCQGKGFICELC 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 392892361  418 TVNEVIYPFNTESTHRCLVCFSAFHVECWR-TSGDCPKCVRRQN 460
Cdd:pfam13901 162 NSDDIIFPFDIDTTSRCEKCKAVFHKSCFRsGASPCPKCERLQK 205
RING-HC_PCGF5 cd16737
RING finger found in polycomb group RING finger protein 5 (PCGF5) and similar proteins; PCGF5, ...
 399-455 6.31e-03

RING finger found in polycomb group RING finger protein 5 (PCGF5) and similar proteins; PCGF5, also known as RING finger protein 159 (RNF159), is one of six PcG RING finger (PCGF) homologs (PCGF1/NSPc1, PCGF2/Mel-18, PCGF3, PCGF4/BMI1, PCGF5, and PCGF6/MBLR) and serves as the core component of a Polycomb repressive complex 1 (PRC1). Like other PCGF homologs, PCGF5 associates with ring finger protein 2 (RNF2) to form a RNF2-PCGF heterodimer, which is catalytically competent as an E3 ubiquitin transferase and is the scaffold for the assembly of additional components. PCGF5 contains a C3HC4-type RING-HC finger.


Pssm-ID: 438395 [Multi-domain]  Cd Length: 95  Bit Score: 36.27  E-value: 6.31e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 392892361 399 NHVMTCTLCkqKGFCCELCTVNEVIYPFntesthrCLVCFsafhVECWRTSGDCPKC 455
Cdd:cd16737    8 NPYITCRIC--KGYLIKPTTVTECLHTF-------CKSCI----VQHFEDSNDCPEC 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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