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Conserved domains on  [gi|392889908|ref|NP_001254097|]
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Mannosyltransferase [Caenorhabditis elegans]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229536)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PMT_2 super family cl21590
Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are ...
 1-425 1.99e-65

Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are not captured by pfam02366.


The actual alignment was detected with superfamily member PLN02816:

Pssm-ID: 473917  Cd Length: 546  Bit Score: 220.68  E-value: 1.99e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908   1 MRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHPALIAVIIKFLDILSLSSQ 80
Cdd:PLN02816  35 IGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTP 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908  81 PLIYHIPRLAHALLFALADFSFYKICLRLcKTKGIAENSFVTYLSSWFVFYCAPRTLSNSLETSLTLIALNWFP-FETKN 159
Cdd:PLN02816 115 YIMIKAPRLMQSIFSAIGDLYLYKLSDAL-YGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPcIRDSS 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908 160 FKGPT---WPyIALGVLTIIIRPTVALIWLVFGVYHLYHSPTPVRLIFQLVLPVTLPILIVTTLIDSWAYGTPTIPLWNF 236
Cdd:PLN02816 194 IDYPVnrkWG-LVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNF 272

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908 237 LQFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFAtityIIVHSLLPHKEQRFLLPIIP 316
Cdd:PLN02816 273 LKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWV----LAIYSILGHKEFRFVLPVLP 348

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908 317 LLCIYAGGAF----------------------QNLKKWRGS---AMAVMIAINIGIALFTSRYHQVGPFTAPRRIMEEwr 371
Cdd:PLN02816 349 IALIFSGYAFaqmevsgssssssvtkkkqvprQNHTKWSPKlrlSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDE-- 426

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 392889908 372 GHHGKL-SVAALMPCYSIPGHAFWHDHLDnLRLLDCSPDLEQlrgpTELDESDQF 425
Cdd:PLN02816 427 AYKGRVkSILFLMPCHSTPYYSTLHRNIP-MQFLDCTPSAEK----GELDESDQF 476
 
Name Accession Description Interval E-value
PLN02816 PLN02816
mannosyltransferase
 1-425 1.99e-65

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 220.68  E-value: 1.99e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908   1 MRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHPALIAVIIKFLDILSLSSQ 80
Cdd:PLN02816  35 IGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTP 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908  81 PLIYHIPRLAHALLFALADFSFYKICLRLcKTKGIAENSFVTYLSSWFVFYCAPRTLSNSLETSLTLIALNWFP-FETKN 159
Cdd:PLN02816 115 YIMIKAPRLMQSIFSAIGDLYLYKLSDAL-YGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPcIRDSS 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908 160 FKGPT---WPyIALGVLTIIIRPTVALIWLVFGVYHLYHSPTPVRLIFQLVLPVTLPILIVTTLIDSWAYGTPTIPLWNF 236
Cdd:PLN02816 194 IDYPVnrkWG-LVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNF 272

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908 237 LQFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFAtityIIVHSLLPHKEQRFLLPIIP 316
Cdd:PLN02816 273 LKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWV----LAIYSILGHKEFRFVLPVLP 348

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908 317 LLCIYAGGAF----------------------QNLKKWRGS---AMAVMIAINIGIALFTSRYHQVGPFTAPRRIMEEwr 371
Cdd:PLN02816 349 IALIFSGYAFaqmevsgssssssvtkkkqvprQNHTKWSPKlrlSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDE-- 426

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 392889908 372 GHHGKL-SVAALMPCYSIPGHAFWHDHLDnLRLLDCSPDLEQlrgpTELDESDQF 425
Cdd:PLN02816 427 AYKGRVkSILFLMPCHSTPYYSTLHRNIP-MQFLDCTPSAEK----GELDESDQF 476
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 11-395 1.76e-61

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 206.83  E-value: 1.76e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908   11 LVVFRCISVyLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEW--RHSLRSFFHPALIAVIIKFLDILSLSSQPLIYHIPR 88
Cdd:pfam03901   6 LLALRLLLA-LLVQTSDPDEHFQSWEPLHYLIFGYGFLTWEWspKYGIRSYLYPLLFALPYYLLARLFGDSKYLVFYAPR 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908   89 LAHALLFALADFSFYK-ICLRLCKTkgIAENSFVTYLSSWFVFYCAPRTLSNSLETSLTLIALNWFPFETKN---FKGPT 164
Cdd:pfam03901  85 LLLGLFSALCDYYLYRaVCRKYGLE--IARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGNTsvsNYKYL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908  165 WPYIALGVLTIIIRPTVALIWLVFGVYHLYHSP-----TPVRLIFQLVLPVTLPILIVTTLIDSWAYGTPTIPLWNFLQF 239
Cdd:pfam03901 163 KAVLLIAALAILGRPTSALLWLPLVLYLLLRLRgkrlkLFLFLAISLGLLVALLVLGAVILIDSYFYGRFVFTPLNFLKY 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908  240 NVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITYI--IVHSLLPHKEQRFLLPIIPL 317
Cdd:pfam03901 243 NVLSNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLRKVSRLSQLLAPILIwlFIYSLQPHKEERFLYPVYPL 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908  318 LCIYAGGAFQNLK--KWRGSAMA----VMIAINIGIALFTSRYHQVGPFTAPRRIMEEWR--------GHHGKLSVAALM 383
Cdd:pfam03901 323 ILLSAAIALTRLSrrSWKVRKKLsllfLLLFFNVSLARLFGLVHQYGAPLAVYDVMSFLNetprenrnPAGPPVNVCIGM 402

                         410
                  ....*....|..
gi 392889908  384 PCYSIPGHAFWH 395
Cdd:pfam03901 403 ECYSTPSSFFLH 414
 
Name Accession Description Interval E-value
PLN02816 PLN02816
mannosyltransferase
 1-425 1.99e-65

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 220.68  E-value: 1.99e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908   1 MRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHPALIAVIIKFLDILSLSSQ 80
Cdd:PLN02816  35 IGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTP 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908  81 PLIYHIPRLAHALLFALADFSFYKICLRLcKTKGIAENSFVTYLSSWFVFYCAPRTLSNSLETSLTLIALNWFP-FETKN 159
Cdd:PLN02816 115 YIMIKAPRLMQSIFSAIGDLYLYKLSDAL-YGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPcIRDSS 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908 160 FKGPT---WPyIALGVLTIIIRPTVALIWLVFGVYHLYHSPTPVRLIFQLVLPVTLPILIVTTLIDSWAYGTPTIPLWNF 236
Cdd:PLN02816 194 IDYPVnrkWG-LVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNF 272

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908 237 LQFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFAtityIIVHSLLPHKEQRFLLPIIP 316
Cdd:PLN02816 273 LKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWV----LAIYSILGHKEFRFVLPVLP 348

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908 317 LLCIYAGGAF----------------------QNLKKWRGS---AMAVMIAINIGIALFTSRYHQVGPFTAPRRIMEEwr 371
Cdd:PLN02816 349 IALIFSGYAFaqmevsgssssssvtkkkqvprQNHTKWSPKlrlSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDE-- 426

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 392889908 372 GHHGKL-SVAALMPCYSIPGHAFWHDHLDnLRLLDCSPDLEQlrgpTELDESDQF 425
Cdd:PLN02816 427 AYKGRVkSILFLMPCHSTPYYSTLHRNIP-MQFLDCTPSAEK----GELDESDQF 476
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 11-395 1.76e-61

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 206.83  E-value: 1.76e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908   11 LVVFRCISVyLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEW--RHSLRSFFHPALIAVIIKFLDILSLSSQPLIYHIPR 88
Cdd:pfam03901   6 LLALRLLLA-LLVQTSDPDEHFQSWEPLHYLIFGYGFLTWEWspKYGIRSYLYPLLFALPYYLLARLFGDSKYLVFYAPR 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908   89 LAHALLFALADFSFYK-ICLRLCKTkgIAENSFVTYLSSWFVFYCAPRTLSNSLETSLTLIALNWFPFETKN---FKGPT 164
Cdd:pfam03901  85 LLLGLFSALCDYYLYRaVCRKYGLE--IARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGNTsvsNYKYL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908  165 WPYIALGVLTIIIRPTVALIWLVFGVYHLYHSP-----TPVRLIFQLVLPVTLPILIVTTLIDSWAYGTPTIPLWNFLQF 239
Cdd:pfam03901 163 KAVLLIAALAILGRPTSALLWLPLVLYLLLRLRgkrlkLFLFLAISLGLLVALLVLGAVILIDSYFYGRFVFTPLNFLKY 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908  240 NVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITYI--IVHSLLPHKEQRFLLPIIPL 317
Cdd:pfam03901 243 NVLSNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLRKVSRLSQLLAPILIwlFIYSLQPHKEERFLYPVYPL 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392889908  318 LCIYAGGAFQNLK--KWRGSAMA----VMIAINIGIALFTSRYHQVGPFTAPRRIMEEWR--------GHHGKLSVAALM 383
Cdd:pfam03901 323 ILLSAAIALTRLSrrSWKVRKKLsllfLLLFFNVSLARLFGLVHQYGAPLAVYDVMSFLNetprenrnPAGPPVNVCIGM 402

                         410
                  ....*....|..
gi 392889908  384 PCYSIPGHAFWH 395
Cdd:pfam03901 403 ECYSTPSSFFLH 414
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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