LIn-8 Domain containing [Caenorhabditis elegans]
Protein Classification
Lin-8 superfamily-containing protein( domain architecture ID 5238)
Lin-8 superfamily-containing protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| Lin-8 super family | cl04022 | Ras-mediated vulval-induction antagonist; LIN-8 is a nuclear protein, present at the sites of ... |
26-90 | 6.49e-25 | ||
Ras-mediated vulval-induction antagonist; LIN-8 is a nuclear protein, present at the sites of transcriptional repressor complexes, which interacts with LIN-35 Rb. Lin35 Rb is a product of the class B synMuv gene lin-35 which silences genes required for vulval specification through chromatin modification and remodelling. The biological role of the interaction has not yet been determined however predictions have been made. The interaction shows that class A synMuv genes control vulval induction through the transcriptional regulation of gene expression. LIN-8 normally functions as part of a protein complex however when the complex is absent, other family members can partially replace LIN-8 activity. The actual alignment was detected with superfamily member pfam03353: Pssm-ID: 397436 Cd Length: 309 Bit Score: 102.06 E-value: 6.49e-25
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| Name | Accession | Description | Interval | E-value | ||
| Lin-8 | pfam03353 | Ras-mediated vulval-induction antagonist; LIN-8 is a nuclear protein, present at the sites of ... |
26-90 | 6.49e-25 | ||
Ras-mediated vulval-induction antagonist; LIN-8 is a nuclear protein, present at the sites of transcriptional repressor complexes, which interacts with LIN-35 Rb. Lin35 Rb is a product of the class B synMuv gene lin-35 which silences genes required for vulval specification through chromatin modification and remodelling. The biological role of the interaction has not yet been determined however predictions have been made. The interaction shows that class A synMuv genes control vulval induction through the transcriptional regulation of gene expression. LIN-8 normally functions as part of a protein complex however when the complex is absent, other family members can partially replace LIN-8 activity. Pssm-ID: 397436 Cd Length: 309 Bit Score: 102.06 E-value: 6.49e-25
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| Name | Accession | Description | Interval | E-value | ||
| Lin-8 | pfam03353 | Ras-mediated vulval-induction antagonist; LIN-8 is a nuclear protein, present at the sites of ... |
26-90 | 6.49e-25 | ||
Ras-mediated vulval-induction antagonist; LIN-8 is a nuclear protein, present at the sites of transcriptional repressor complexes, which interacts with LIN-35 Rb. Lin35 Rb is a product of the class B synMuv gene lin-35 which silences genes required for vulval specification through chromatin modification and remodelling. The biological role of the interaction has not yet been determined however predictions have been made. The interaction shows that class A synMuv genes control vulval induction through the transcriptional regulation of gene expression. LIN-8 normally functions as part of a protein complex however when the complex is absent, other family members can partially replace LIN-8 activity. Pssm-ID: 397436 Cd Length: 309 Bit Score: 102.06 E-value: 6.49e-25
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