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Conserved domains on  [gi|392887836|ref|NP_001252409|]
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CTLH domain-containing protein [Caenorhabditis elegans]

Protein Classification

topless-related protein; WD40 repeat domain-containing protein( domain architecture ID 10652955)

topless-related protein may act as transcription corepressor| WD40 repeat domain-containing protein folds into a beta-propeller structure and functions as a scaffold, providing a platform for the interaction and assembly of several proteins into a signalosome; similar to a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CTLH smart00668
C-terminal to LisH motif; Alpha-helical motif of unknown function.
 55-113 6.57e-05

C-terminal to LisH motif; Alpha-helical motif of unknown function.


:

Pssm-ID: 128914  Cd Length: 58  Bit Score: 40.25  E-value: 6.57e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 392887836    55 YYAQRKEITDMILKAARGAEIhEKIEKYFPGLVEDDANVHLLILCLRYIDLANTLHEPP 113
Cdd:smart00668   1 EFDERKRIRELILKGDWDEAL-EWLSSLKPPLLERNSKLEFELRKQKFLELVRQGKLEE 58
 
Name Accession Description Interval E-value
CTLH smart00668
C-terminal to LisH motif; Alpha-helical motif of unknown function.
 55-113 6.57e-05

C-terminal to LisH motif; Alpha-helical motif of unknown function.


Pssm-ID: 128914  Cd Length: 58  Bit Score: 40.25  E-value: 6.57e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 392887836    55 YYAQRKEITDMILKAARGAEIhEKIEKYFPGLVEDDANVHLLILCLRYIDLANTLHEPP 113
Cdd:smart00668   1 EFDERKRIRELILKGDWDEAL-EWLSSLKPPLLERNSKLEFELRKQKFLELVRQGKLEE 58
 
Name Accession Description Interval E-value
CTLH smart00668
C-terminal to LisH motif; Alpha-helical motif of unknown function.
 55-113 6.57e-05

C-terminal to LisH motif; Alpha-helical motif of unknown function.


Pssm-ID: 128914  Cd Length: 58  Bit Score: 40.25  E-value: 6.57e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 392887836    55 YYAQRKEITDMILKAARGAEIhEKIEKYFPGLVEDDANVHLLILCLRYIDLANTLHEPP 113
Cdd:smart00668   1 EFDERKRIRELILKGDWDEAL-EWLSSLKPPLLERNSKLEFELRKQKFLELVRQGKLEE 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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