histone deacetylase complex subunit SAP30L [Macaca mulatta]
histone deacetylase complex subunit SAP30 Sin3-binding domain-containing protein( domain architecture ID 10620573)
histone deacetylase complex subunit SAP30 Sin3-binding domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | ||
zf-SAP30 | pfam13866 | SAP30 zinc-finger; SAP30 is a subunit of the histone deacetylase complex, and this domain is a ... |
25-96 | 4.87e-42 | ||
SAP30 zinc-finger; SAP30 is a subunit of the histone deacetylase complex, and this domain is a zinc-finger. Solution of the structure shows a novel fold comprising two beta-strands and two alpha-helices with the zinc organizing centre showing remote resemblance to the treble clef motif. In silico analysis of the structure revealed a highly conserved surface dominated by basic residues. NMR-based analysis of potential ligands for the SAP30 zn-finger motif indicated a strong preference for nucleic acid substrates. The zinc-finger of SAP3 probably functions as a double-stranded DNA-binding motif, thereby expanding the known functions of both SAP30 and the mammalian Sin3 co-repressor complex. : Pssm-ID: 404707 Cd Length: 72 Bit Score: 135.63 E-value: 4.87e-42
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SAP30_Sin3_bdg | pfam13867 | Sin3 binding region of histone deacetylase complex subunit SAP30; This C-terminal domain of ... |
115-167 | 6.28e-27 | ||
Sin3 binding region of histone deacetylase complex subunit SAP30; This C-terminal domain of the SAP30 proteins appears to be the binding region for Sin3. : Pssm-ID: 464006 Cd Length: 53 Bit Score: 96.46 E-value: 6.28e-27
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Name | Accession | Description | Interval | E-value | ||
zf-SAP30 | pfam13866 | SAP30 zinc-finger; SAP30 is a subunit of the histone deacetylase complex, and this domain is a ... |
25-96 | 4.87e-42 | ||
SAP30 zinc-finger; SAP30 is a subunit of the histone deacetylase complex, and this domain is a zinc-finger. Solution of the structure shows a novel fold comprising two beta-strands and two alpha-helices with the zinc organizing centre showing remote resemblance to the treble clef motif. In silico analysis of the structure revealed a highly conserved surface dominated by basic residues. NMR-based analysis of potential ligands for the SAP30 zn-finger motif indicated a strong preference for nucleic acid substrates. The zinc-finger of SAP3 probably functions as a double-stranded DNA-binding motif, thereby expanding the known functions of both SAP30 and the mammalian Sin3 co-repressor complex. Pssm-ID: 404707 Cd Length: 72 Bit Score: 135.63 E-value: 4.87e-42
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SAP30_Sin3_bdg | pfam13867 | Sin3 binding region of histone deacetylase complex subunit SAP30; This C-terminal domain of ... |
115-167 | 6.28e-27 | ||
Sin3 binding region of histone deacetylase complex subunit SAP30; This C-terminal domain of the SAP30 proteins appears to be the binding region for Sin3. Pssm-ID: 464006 Cd Length: 53 Bit Score: 96.46 E-value: 6.28e-27
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Name | Accession | Description | Interval | E-value | ||
zf-SAP30 | pfam13866 | SAP30 zinc-finger; SAP30 is a subunit of the histone deacetylase complex, and this domain is a ... |
25-96 | 4.87e-42 | ||
SAP30 zinc-finger; SAP30 is a subunit of the histone deacetylase complex, and this domain is a zinc-finger. Solution of the structure shows a novel fold comprising two beta-strands and two alpha-helices with the zinc organizing centre showing remote resemblance to the treble clef motif. In silico analysis of the structure revealed a highly conserved surface dominated by basic residues. NMR-based analysis of potential ligands for the SAP30 zn-finger motif indicated a strong preference for nucleic acid substrates. The zinc-finger of SAP3 probably functions as a double-stranded DNA-binding motif, thereby expanding the known functions of both SAP30 and the mammalian Sin3 co-repressor complex. Pssm-ID: 404707 Cd Length: 72 Bit Score: 135.63 E-value: 4.87e-42
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SAP30_Sin3_bdg | pfam13867 | Sin3 binding region of histone deacetylase complex subunit SAP30; This C-terminal domain of ... |
115-167 | 6.28e-27 | ||
Sin3 binding region of histone deacetylase complex subunit SAP30; This C-terminal domain of the SAP30 proteins appears to be the binding region for Sin3. Pssm-ID: 464006 Cd Length: 53 Bit Score: 96.46 E-value: 6.28e-27
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Blast search parameters | ||||
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