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Conserved domains on  [gi|383872260|ref|NP_001244507|]
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probable E3 ubiquitin-protein ligase HERC4 [Macaca mulatta]

Protein Classification

E3 ubiquitin-protein ligase HERC family protein( domain architecture ID 18804227)

E3 ubiquitin-protein ligase HERC (HECT and RCC1 domain) family protein similar to human E3 ISG15--protein ligase HERC5, the major E3 ligase for ISG15 conjugation, that functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 709-1055 1.44e-145

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


:

Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 438.92  E-value: 1.44e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  709 LILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDS-RLIWFSDK 787
Cdd:cd00078     1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  788 TFEDSD---LFHLIGVICGLAIYNFTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDdiEETFCLNF 864
Cdd:cd00078    81 SFADEDhlkLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGD--EDDLELTF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  865 TITVEN-FGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIG 943
Cdd:cd00078   159 TIELDSsFGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  944 NTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKQQFLLFLTGSDRIPILGMKSL--KLVIQSTGGGEEYLPV 1021
Cdd:cd00078   239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLnpKFTIRRVGSPDDRLPT 318

                         330       340       350
                  ....*....|....*....|....*....|....
gi 383872260 1022 SHTCFNLLDLPKYTDKETLRSKLIQAIDHNEGFS 1055
Cdd:cd00078   319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGFG 352
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 3-338 2.13e-85

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 279.55  E-value: 2.13e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    3 CWGNASFGQLGLGgiDEEIVLEPRKSDFFINkkVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVA 80
Cdd:COG5184    21 CWGDNSYGQLGDG--TTTDRSTPVRVPGLSN--VVAVAAGGDHTCALKADGTVWCWGNNSYGQLGdgTTTDRTTPVKVPG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   81 LDaqNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGlLGSEECIRVPRNI-KSLSDiqIIQVACGYYHSLALSKASEVF 159
Cdd:COG5184    97 LT--GVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLG-DGTTTNRLTPVQVdAGLSG--VVAIAAGGYHTCALKSDGTVW 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  160 CWGQNKYGQLGLGTDcKKQTSPQLIKSLLGIpfMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSL 239
Cdd:COG5184   172 CWGANSYGQLGDGTT-TDRPTPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCWGSNSSGQLGDGTTTDRATPVQVAGL 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  240 rsQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGsiVTQIACGRQHTSAfVPSSGRIYSF 319
Cdd:COG5184   249 --TGVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSG--VVAVAAGSSHTCA-LLTDGTVWCW 323

                         330
                  ....*....|....*....
gi 383872260  320 GLGGNGQLGTGSTSNRKSP 338
Cdd:COG5184   324 GDNAYGQLGDGTTTDRSTP 342
 
Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 709-1055 1.44e-145

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 438.92  E-value: 1.44e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  709 LILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDS-RLIWFSDK 787
Cdd:cd00078     1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  788 TFEDSD---LFHLIGVICGLAIYNFTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDdiEETFCLNF 864
Cdd:cd00078    81 SFADEDhlkLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGD--EDDLELTF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  865 TITVEN-FGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIG 943
Cdd:cd00078   159 TIELDSsFGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  944 NTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKQQFLLFLTGSDRIPILGMKSL--KLVIQSTGGGEEYLPV 1021
Cdd:cd00078   239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLnpKFTIRRVGSPDDRLPT 318

                         330       340       350
                  ....*....|....*....|....*....|....
gi 383872260 1022 SHTCFNLLDLPKYTDKETLRSKLIQAIDHNEGFS 1055
Cdd:cd00078   319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGFG 352
HECTc smart00119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
 735-1054 2.17e-113

Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.


Pssm-ID: 214523  Cd Length: 328  Bit Score: 353.85  E-value: 2.17e-113
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    735 KKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSD----LFHLIGVICGLAIYNFT 810
Cdd:smart00119    4 KRVLEIEFEGEEGLDGGGVTREFFFLLSKELFNPDYGLFRYSPNDYLLYPNPRSGFANEehlsYFRFIGRVLGKALYDNR 83

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    811 IVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQL-LDYPEDDIEEtfcLNFTITVEN-FGATEVKELVLNGADTAV 888
Cdd:smart00119   84 LLDLFFARPFYKKLLGKPVTLHDLESLDPELYKSLKWLlLNNDTSEELD---LTFSIVLTSeFGQVKVVELKPGGSNIPV 160

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    889 NKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPT 968
Cdd:smart00119  161 TEENKKEYVHLVIEYRLNKGIEKQLEAFREGFSEVIPENLLKLFDPEELELLICGSPEIDVDDLKSNTEYKGGYSANSQT 240

                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    969 IKIFWEVFHELPLEKKQQFLLFLTGSDRIPILGMKSL--KLVIQSTGGGEEYLPVSHTCFNLLDLPKYTDKETLRSKLIQ 1046
Cdd:smart00119  241 IKWFWEVVESFTNEERRKLLQFVTGSSRLPVGGFAALspKFTIRKAGSDDERLPTAHTCFNRLKLPPYSSKEILREKLLL 320


                    ....*...
gi 383872260   1047 AIDHNEGF 1054
Cdd:smart00119  321 AINEGKGF 328
HECT pfam00632
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
 759-1057 8.15e-105

HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.


Pssm-ID: 459880  Cd Length: 304  Bit Score: 330.34  E-value: 8.15e-105
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   759 LLIMRELLDPKYGMFRY-YEDSRLIWFSDKTFED-----SDLFHLIGVICGLAIYNFTIVDLHFPLALYKKLLKKKPSLD 832
Cdd:pfam00632    1 TLLSKELFDPNYGLFEYeTEDDRTYWFNPSSSESpdlelLDYFKFLGKLLGKAIYNGILLDLPFPPFFYKKLLGEPLTLE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   833 DLKELMPDVGRSMQQLLDYpEDDIEETFCLNFTITVenFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASL 912
Cdd:pfam00632   81 DLESIDPELYKSLKSLLNM-DNDDDEDLGLTFTIPV--FGESKTIELIPNGRNIPVTNENKEEYIRLYVDYRLNKSIEPQ 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   913 FDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKQQFLLFLT 992
Cdd:pfam00632  158 LEAFRKGFYSVIPKEALSLFTPEELELLICGSPEIDVEDLKKNTEYDGGYTKNSPTIQWFWEILEEFSPEQRRLFLKFVT 237

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 383872260   993 GSDRIPILGMKSL-KLVIQSTGG-GEEYLPVSHTCFNLLDLPKYTDKETLRSKLIQAIDHNEGFSLI 1057
Cdd:pfam00632  238 GSSRLPVGGFKSLpKFTIVRKGGdDDDRLPTAHTCFNRLKLPDYSSKEILKEKLLIAIEEGEGFGLS 304
HUL4 COG5021
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
660-1057 1.07e-90

Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227354 [Multi-domain]  Cd Length: 872  Bit Score: 309.77  E-value: 1.07e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  660 TYPFVFDAQAKTTLLQTD-----AVLQMQMAIDQ---AHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKN 731
Cdd:COG5021   458 LYRFYFVEHRKKTLTKNDsrlgsFISLNKLDIRRikeDKRRKLFYSLKQKAKIFDPYLHIKVRRDRVFEDSYREIMDESG 537

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  732 IDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIW----FSDKTFEDSDLFHLIGVICGLAIY 807
Cdd:COG5021   538 DDLKKTLEIEFVGEEGIDAGGLTREWLFLLSKEMFNPDYGLFEYITEDLYTLpinpLSSINPEHLSYFKFLGRVIGKAIY 617

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  808 NFTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDdiEETFCLNFTITVENFGATEVKELVLNGADTA 887
Cdd:COG5021   618 DSRILDVQFSKAFYKKLLGKPVSLVDLESLDPELYRSLVWLLNNDID--ETILDLTFTVEDDSFGESRTVELIPNGRNIS 695

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  888 VNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIG-NTNYDWKELEKNTEYKGeYWAEH 966
Cdd:COG5021   696 VTNENKKEYVKKVVDYKLNKRVEKQFSAFKSGFSEIIPPDLLQIFDESELELLIGGiPEDIDIDDWKSNTAYHG-YTEDS 774

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  967 PTIKIFWEVFHELPLEKKQQFLLFLTGSDRIPILGMKSL-------KLVIQSTGGGEEYLPVSHTCFNLLDLPKYTDKET 1039
Cdd:COG5021   775 PIIVWFWEIISEFDFEERAKLLQFVTGTSRIPINGFKDLqgsdgvrKFTIEKGGTDDDRLPSAHTCFNRLKLPEYSSKEK 854

                         410
                  ....*....|....*...
gi 383872260 1040 LRSKLIQAIDHNEGFSLI 1057
Cdd:COG5021   855 LRSKLLTAINEGAGFGLL 872
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 3-338 2.13e-85

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 279.55  E-value: 2.13e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    3 CWGNASFGQLGLGgiDEEIVLEPRKSDFFINkkVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVA 80
Cdd:COG5184    21 CWGDNSYGQLGDG--TTTDRSTPVRVPGLSN--VVAVAAGGDHTCALKADGTVWCWGNNSYGQLGdgTTTDRTTPVKVPG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   81 LDaqNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGlLGSEECIRVPRNI-KSLSDiqIIQVACGYYHSLALSKASEVF 159
Cdd:COG5184    97 LT--GVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLG-DGTTTNRLTPVQVdAGLSG--VVAIAAGGYHTCALKSDGTVW 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  160 CWGQNKYGQLGLGTDcKKQTSPQLIKSLLGIpfMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSL 239
Cdd:COG5184   172 CWGANSYGQLGDGTT-TDRPTPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCWGSNSSGQLGDGTTTDRATPVQVAGL 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  240 rsQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGsiVTQIACGRQHTSAfVPSSGRIYSF 319
Cdd:COG5184   249 --TGVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSG--VVAVAAGSSHTCA-LLTDGTVWCW 323

                         330
                  ....*....|....*....
gi 383872260  320 GLGGNGQLGTGSTSNRKSP 338
Cdd:COG5184   324 GDNAYGQLGDGTTTDRSTP 342
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
208-257 4.64e-16

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 72.94  E-value: 4.64e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 383872260   208 SGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 257
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 709-1055 1.44e-145

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 438.92  E-value: 1.44e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  709 LILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDS-RLIWFSDK 787
Cdd:cd00078     1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  788 TFEDSD---LFHLIGVICGLAIYNFTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDdiEETFCLNF 864
Cdd:cd00078    81 SFADEDhlkLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGD--EDDLELTF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  865 TITVEN-FGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIG 943
Cdd:cd00078   159 TIELDSsFGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  944 NTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKQQFLLFLTGSDRIPILGMKSL--KLVIQSTGGGEEYLPV 1021
Cdd:cd00078   239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLnpKFTIRRVGSPDDRLPT 318

                         330       340       350
                  ....*....|....*....|....*....|....
gi 383872260 1022 SHTCFNLLDLPKYTDKETLRSKLIQAIDHNEGFS 1055
Cdd:cd00078   319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGFG 352
HECTc smart00119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
 735-1054 2.17e-113

Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.


Pssm-ID: 214523  Cd Length: 328  Bit Score: 353.85  E-value: 2.17e-113
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    735 KKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSD----LFHLIGVICGLAIYNFT 810
Cdd:smart00119    4 KRVLEIEFEGEEGLDGGGVTREFFFLLSKELFNPDYGLFRYSPNDYLLYPNPRSGFANEehlsYFRFIGRVLGKALYDNR 83

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    811 IVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQL-LDYPEDDIEEtfcLNFTITVEN-FGATEVKELVLNGADTAV 888
Cdd:smart00119   84 LLDLFFARPFYKKLLGKPVTLHDLESLDPELYKSLKWLlLNNDTSEELD---LTFSIVLTSeFGQVKVVELKPGGSNIPV 160

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    889 NKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPT 968
Cdd:smart00119  161 TEENKKEYVHLVIEYRLNKGIEKQLEAFREGFSEVIPENLLKLFDPEELELLICGSPEIDVDDLKSNTEYKGGYSANSQT 240

                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    969 IKIFWEVFHELPLEKKQQFLLFLTGSDRIPILGMKSL--KLVIQSTGGGEEYLPVSHTCFNLLDLPKYTDKETLRSKLIQ 1046
Cdd:smart00119  241 IKWFWEVVESFTNEERRKLLQFVTGSSRLPVGGFAALspKFTIRKAGSDDERLPTAHTCFNRLKLPPYSSKEILREKLLL 320


                    ....*...
gi 383872260   1047 AIDHNEGF 1054
Cdd:smart00119  321 AINEGKGF 328
HECT pfam00632
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
 759-1057 8.15e-105

HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.


Pssm-ID: 459880  Cd Length: 304  Bit Score: 330.34  E-value: 8.15e-105
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   759 LLIMRELLDPKYGMFRY-YEDSRLIWFSDKTFED-----SDLFHLIGVICGLAIYNFTIVDLHFPLALYKKLLKKKPSLD 832
Cdd:pfam00632    1 TLLSKELFDPNYGLFEYeTEDDRTYWFNPSSSESpdlelLDYFKFLGKLLGKAIYNGILLDLPFPPFFYKKLLGEPLTLE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   833 DLKELMPDVGRSMQQLLDYpEDDIEETFCLNFTITVenFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASL 912
Cdd:pfam00632   81 DLESIDPELYKSLKSLLNM-DNDDDEDLGLTFTIPV--FGESKTIELIPNGRNIPVTNENKEEYIRLYVDYRLNKSIEPQ 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   913 FDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKQQFLLFLT 992
Cdd:pfam00632  158 LEAFRKGFYSVIPKEALSLFTPEELELLICGSPEIDVEDLKKNTEYDGGYTKNSPTIQWFWEILEEFSPEQRRLFLKFVT 237

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 383872260   993 GSDRIPILGMKSL-KLVIQSTGG-GEEYLPVSHTCFNLLDLPKYTDKETLRSKLIQAIDHNEGFSLI 1057
Cdd:pfam00632  238 GSSRLPVGGFKSLpKFTIVRKGGdDDDRLPTAHTCFNRLKLPDYSSKEILKEKLLIAIEEGEGFGLS 304
HUL4 COG5021
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
660-1057 1.07e-90

Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227354 [Multi-domain]  Cd Length: 872  Bit Score: 309.77  E-value: 1.07e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  660 TYPFVFDAQAKTTLLQTD-----AVLQMQMAIDQ---AHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKN 731
Cdd:COG5021   458 LYRFYFVEHRKKTLTKNDsrlgsFISLNKLDIRRikeDKRRKLFYSLKQKAKIFDPYLHIKVRRDRVFEDSYREIMDESG 537

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  732 IDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIW----FSDKTFEDSDLFHLIGVICGLAIY 807
Cdd:COG5021   538 DDLKKTLEIEFVGEEGIDAGGLTREWLFLLSKEMFNPDYGLFEYITEDLYTLpinpLSSINPEHLSYFKFLGRVIGKAIY 617

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  808 NFTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDdiEETFCLNFTITVENFGATEVKELVLNGADTA 887
Cdd:COG5021   618 DSRILDVQFSKAFYKKLLGKPVSLVDLESLDPELYRSLVWLLNNDID--ETILDLTFTVEDDSFGESRTVELIPNGRNIS 695

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  888 VNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIG-NTNYDWKELEKNTEYKGeYWAEH 966
Cdd:COG5021   696 VTNENKKEYVKKVVDYKLNKRVEKQFSAFKSGFSEIIPPDLLQIFDESELELLIGGiPEDIDIDDWKSNTAYHG-YTEDS 774

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  967 PTIKIFWEVFHELPLEKKQQFLLFLTGSDRIPILGMKSL-------KLVIQSTGGGEEYLPVSHTCFNLLDLPKYTDKET 1039
Cdd:COG5021   775 PIIVWFWEIISEFDFEERAKLLQFVTGTSRIPINGFKDLqgsdgvrKFTIEKGGTDDDRLPSAHTCFNRLKLPEYSSKEK 854

                         410
                  ....*....|....*...
gi 383872260 1040 LRSKLIQAIDHNEGFSLI 1057
Cdd:COG5021   855 LRSKLLTAINEGAGFGLL 872
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 3-338 2.13e-85

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 279.55  E-value: 2.13e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    3 CWGNASFGQLGLGgiDEEIVLEPRKSDFFINkkVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVA 80
Cdd:COG5184    21 CWGDNSYGQLGDG--TTTDRSTPVRVPGLSN--VVAVAAGGDHTCALKADGTVWCWGNNSYGQLGdgTTTDRTTPVKVPG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   81 LDaqNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGlLGSEECIRVPRNI-KSLSDiqIIQVACGYYHSLALSKASEVF 159
Cdd:COG5184    97 LT--GVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLG-DGTTTNRLTPVQVdAGLSG--VVAIAAGGYHTCALKSDGTVW 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  160 CWGQNKYGQLGLGTDcKKQTSPQLIKSLLGIpfMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSL 239
Cdd:COG5184   172 CWGANSYGQLGDGTT-TDRPTPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCWGSNSSGQLGDGTTTDRATPVQVAGL 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  240 rsQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGsiVTQIACGRQHTSAfVPSSGRIYSF 319
Cdd:COG5184   249 --TGVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSG--VVAVAAGSSHTCA-LLTDGTVWCW 323

                         330
                  ....*....|....*....
gi 383872260  320 GLGGNGQLGTGSTSNRKSP 338
Cdd:COG5184   324 GDNAYGQLGDGTTTDRSTP 342
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 37-343 1.44e-81

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 269.15  E-value: 1.44e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   37 RDVGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVALDaqNIVAVSCGEAHTLALNDKGQVYAWGLDSDG 114
Cdd:COG5184     1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGdgTTTDRSTPVRVPGLS--NVVAVAAGGDHTCALKADGTVWCWGNNSYG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  115 QLGlLGSEECIRVPRNIKSLSDiqIIQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDcKKQTSPQLIKSLLGiPFMQ 194
Cdd:COG5184    79 QLG-DGTTTDRTTPVKVPGLTG--VVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTT-TNRLTPVQVDAGLS-GVVA 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260  195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSqkIVYICCGEDHTAALTKEGGVFTFGAGGYGQL 274
Cdd:COG5184   154 IAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSG--VVAVAAGGDHSCALKSDGTVWCWGSNSSGQL 231

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 383872260  275 GHNSTSHEINPRKVFELMGsiVTQIACGRQHTSAfVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKG 343
Cdd:COG5184   232 GDGTTTDRATPVQVAGLTG--VVAIAAGGSHTCA-LKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPG 297
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 1-182 1.45e-41

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 156.29  E-value: 1.45e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260    1 MLCWGNASFGQLGLGGIDEEIVlePRKSDFFINkkVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE--KSRKKPEQV 78
Cdd:COG5184   170 VWCWGANSYGQLGDGTTTDRPT--PVQVGGLSG--VVAVAAGGDHSCALKSDGTVWCWGSNSSGQLGDGttTDRATPVQV 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383872260   79 VALDaqNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGlLGSEECIRVPRNIKSLSDiqIIQVACGYYHSLALSKASEV 158
Cdd:COG5184   246 AGLT--GVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLG-DGTTTDRSTPVKVPGLSG--VVAVAAGSSHTCALLTDGTV 320

                         170       180
                  ....*....|....*....|....
gi 383872260  159 FCWGQNKYGQLGLGTDcKKQTSPQ 182
Cdd:COG5184   321 WCWGDNAYGQLGDGTT-TDRSTPV 343
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
208-257 4.64e-16

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 72.94  E-value: 4.64e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 383872260   208 SGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 257
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
102-152 3.49e-15

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 70.24  E-value: 3.49e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 383872260   102 KGQVYAWGLDSDGQLGLlGSEECIRVPRNIKSLSDIQIIQVACGYYHSLAL 152
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGL-GTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
157-205 1.57e-13

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 65.62  E-value: 1.57e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 383872260   157 EVFCWGQNKYGQLGLGTDcKKQTSPQLIKSLLGIPFMQVAAGGAHSFVL 205
Cdd:pfam00415    3 RVYTWGRNDYGQLGLGTT-ENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
52-99 2.51e-13

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 65.23  E-value: 2.51e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 383872260    52 DGTVYTCGCNDLGQLGH--EKSRKKPEQVVALDAQNIVAVSCGEAHTLAL 99
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLgtTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
260-308 2.66e-13

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 65.23  E-value: 2.66e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 383872260   260 EGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTQIACGRQHTSA 308
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVA 49
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
139-168 2.38e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 53.20  E-value: 2.38e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 383872260   139 IIQVACGYYHSLALSKASEVFCWGQNKYGQ 168
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
86-115 3.64e-08

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 50.12  E-value: 3.64e-08
                           10        20        30
                   ....*....|....*....|....*....|
gi 383872260    86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQ 115
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
36-65 1.21e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 48.57  E-value: 1.21e-07
                           10        20        30
                   ....*....|....*....|....*....|
gi 383872260    36 VRDVGCGLRHTVFVLDDGTVYTCGCNDLGQ 65
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
3-49 1.34e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 49.05  E-value: 1.34e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 383872260     3 CWGNASFGQLGLGgiDEEIVLEPRKSDFFINKKVRDVGCGLRHTVFV 49
Cdd:pfam00415    6 TWGRNDYGQLGLG--TTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
194-221 1.79e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 45.11  E-value: 1.79e-06
                           10        20
                   ....*....|....*....|....*...
gi 383872260   194 QVAAGGAHSFVLTLSGAIFGWGRNKFGQ 221
Cdd:pfam13540    3 SVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
313-343 1.45e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 43.27  E-value: 1.45e-05
                           10        20        30
                   ....*....|....*....|....*....|.
gi 383872260   313 SGRIYSFGLGGNGQLGTGSTSNRKSPFTVKG 343
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEG 31
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
244-273 1.55e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 42.41  E-value: 1.55e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 383872260   244 IVYICCGEDHTAALTKEGGVFTFGAGGYGQ 273
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
296-326 6.77e-04

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 37.79  E-value: 6.77e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 383872260   296 VTQIACGRQHTsAFVPSSGRIYSFGLGGNGQ 326
Cdd:pfam13540    1 VVSVAAGDNHT-LALTSDGRVYCWGDNSYGQ 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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