NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|383873113|ref|NP_001244430|]
View 

glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial [Macaca mulatta]

Protein Classification

amidase( domain architecture ID 10000643)

amidase catalyzes the hydrolysis of a monocarboxylic acid amide to form a monocarboxylate and ammonia; similar to aspartyl/glutamyl-tRNA synthase subunit A (GatA), which is part of a heterotrimeric complex that forms correctly charged Gln-tRNA(Gln) or Asn-tRNA(Asn) through the transamidation of misacylated Glu-tRNA(Gln) or Asp-tRNA(Asn)

CATH:  3.90.1300.10
Gene Ontology:  GO:0003824
SCOP:  3001251|4002446

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 1-496 3.42e-163

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


:

Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 471.56  E-value: 3.42e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   1 MLGRTLQEVSAALKQGQITPTELCQKCLSLIKKT-KFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNF 79
Cdd:COG0154    4 LAELSAAELAAALRAGEVSAVELVEAALARIEAVnPALNAFVTVDAERALAEARAADARRAAGEALGPLAGVPVAVKDLI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  80 STSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWsyskqyrekrkqNPHsk 159
Cdd:COG0154   84 DVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPW------------DPDrt 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 160 nedsdwlitggssggSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDD 239
Cdd:COG0154  152 pgg--------ssggSAAAVAAGLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVAD 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 240 AAIVLGALAGPDPKDSTTVHDPInKPFMLPSLADVSKLCIGIPKEYLIPE-LSSEVRSLWSKAADLFESEGAKVLEVSLP 318
Cdd:COG0154  224 AALLLDVLAGPDPRDPTSAPAPV-PDYLAALDRDLKGLRIGVPREYFGGDgVDPEVAAAVEAAAAALEALGAEVVEVDLP 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 319 HTSYSIVCYHVLCTSEVASNMArfdglqyghrcdinvsteAMYaATRREGFNDVVRGRILSGNFFllkenYENYFVKAQK 398
Cdd:COG0154  303 DLDEALAAYYTIAAAEAAANLA------------------DLL-RTRPEGFGPEVRRRILLGAYY-----SAADYLKAQR 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 399 VRRLIANDFVNAFNsGVDVLLTPTTLSEAVPYLEFIKEDN--RTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQ 476
Cdd:COG0154  359 VRALLRRDFAAAFE-DYDVLLTPTTPTPAPPIGELDADIDpaLAMNYLLDRFTAPANLAGLPALSVPAGFTADGLPVGLQ 437

                        490       500
                 ....*....|....*....|
gi 383873113 477 FIGRAFCDQQLLTVAKWFEK 496
Cdd:COG0154  438 LIGPPGDEATLLRLAAALEQ 457
 
Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 1-496 3.42e-163

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 471.56  E-value: 3.42e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   1 MLGRTLQEVSAALKQGQITPTELCQKCLSLIKKT-KFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNF 79
Cdd:COG0154    4 LAELSAAELAAALRAGEVSAVELVEAALARIEAVnPALNAFVTVDAERALAEARAADARRAAGEALGPLAGVPVAVKDLI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  80 STSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWsyskqyrekrkqNPHsk 159
Cdd:COG0154   84 DVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPW------------DPDrt 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 160 nedsdwlitggssggSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDD 239
Cdd:COG0154  152 pgg--------ssggSAAAVAAGLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVAD 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 240 AAIVLGALAGPDPKDSTTVHDPInKPFMLPSLADVSKLCIGIPKEYLIPE-LSSEVRSLWSKAADLFESEGAKVLEVSLP 318
Cdd:COG0154  224 AALLLDVLAGPDPRDPTSAPAPV-PDYLAALDRDLKGLRIGVPREYFGGDgVDPEVAAAVEAAAAALEALGAEVVEVDLP 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 319 HTSYSIVCYHVLCTSEVASNMArfdglqyghrcdinvsteAMYaATRREGFNDVVRGRILSGNFFllkenYENYFVKAQK 398
Cdd:COG0154  303 DLDEALAAYYTIAAAEAAANLA------------------DLL-RTRPEGFGPEVRRRILLGAYY-----SAADYLKAQR 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 399 VRRLIANDFVNAFNsGVDVLLTPTTLSEAVPYLEFIKEDN--RTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQ 476
Cdd:COG0154  359 VRALLRRDFAAAFE-DYDVLLTPTTPTPAPPIGELDADIDpaLAMNYLLDRFTAPANLAGLPALSVPAGFTADGLPVGLQ 437

                        490       500
                 ....*....|....*....|
gi 383873113 477 FIGRAFCDQQLLTVAKWFEK 496
Cdd:COG0154  438 LIGPPGDEATLLRLAAALEQ 457
gatA TIGR00132
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase ...
 11-496 2.98e-158

aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase is missing. tRNA(Gln) is misacylated with Glu after which a heterotrimeric amidotransferase converts Glu to Gln. This model represents the amidase chain of that heterotrimer, encoded by the gatA gene. In the Archaea, Asn--tRNA ligase is also missing. This amidase subunit may also function in the conversion of Asp-tRNA(Asn) to Asn-tRNA(Asn), presumably with a different recognition unit to replace gatB. Both Methanococcus jannaschii and Methanobacterium thermoautotrophicum have both authentic gatB and a gatB-related gene, but only one gene like gatA. It has been shown that gatA can be expressed only when gatC is also expressed. In most species expressing the amidotransferase, the gatC ortholog is about 90 residues in length, but in Mycoplasma genitalium and Mycoplasma pneumoniae the gatC equivalent is as the C-terminal domain of a much longer protein. Not surprisingly, the Mycoplasmas also represent the most atypical lineage of gatA orthology. This orthology group is more narrowly defined here than in Proc Natl Acad Aci USA 94, 11819-11826 (1997). In particular, a Rhodococcus homolog found in association with nitrile hydratase genes and described as an enantiomer-selective amidase active on several 2-aryl propionamides, is excluded here. It is likely, however, that the amidase subunit GatA is not exclusively a part of the Glu-tRNA(Gln) amidotransferase heterotrimer and restricted to that function in all species. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272925 [Multi-domain]  Cd Length: 460  Bit Score: 458.73  E-value: 2.98e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   11 AALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRykngqSLGDLDGIPVAVKDNFSTSGIETTCA 89
Cdd:TIGR00132   3 QLLKKKEISIKEVLEASLDRIEANKdKINAFLEVTVEKALKQAKKLDKA-----ILTPLAGIPIAVKDNISTKGIVTTCA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   90 SNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWsyskqyrekrkqnphskNEDsdwLITG 169
Cdd:TIGR00132  78 SKILENYIPPYDATVIERLKQAGALIIGKTNMDEFAMGSSTETSAFGPTKNPW-----------------NLD---RVPG 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  170 GSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAG 249
Cdd:TIGR00132 138 GSSGGSAAAVAADLAPFSLGSDTGGSIRQPASFCGVVGFKPTYGRVSRYGLVAYASSLDQIGPFARTVEDIALLLDVISG 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  250 PDPKDSTTVHDPInkPFMLPSLADVSK-LCIGIPKEyLIPELSSEVRSLWSKAADLFESEGAKVLEVSLPHTSYSIVCYH 328
Cdd:TIGR00132 218 HDKRDSTSAKVPD--PEFFEELKKDLKgLKVGVVKE-FSEEMDKEVQEKFENALEVLEELGAEIVEVSFPHVKYALPIYY 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  329 VLCTSEVASNMARFDGLQYGHRCDINVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFV 408
Cdd:TIGR00132 295 IISPSEASSNLARYDGIRYGYRIEEPNSLKELYAKTRAEGFGEEVKRRIMLGNYALSAGYYDKYYLKAQKVRTLIIDDFL 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  409 NAFnSGVDVLLTPTTlseavPYLEFI---KEDNRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQ 485
Cdd:TIGR00132 375 KLF-EEVDVIVSPTA-----PTLPFKigeKLDDPLEMYLSDILTVPANLAGLPAISVPCGVKEKGLPIGLQIIGKCFDDK 448

                         490
                  ....*....|.
gi 383873113  486 QLLTVAKWFEK 496
Cdd:TIGR00132 449 TLLQVSYAFEQ 459
Amidase pfam01425
Amidase;
37-488 2.74e-133

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 394.36  E-value: 2.74e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   37 LNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLM 116
Cdd:pfam01425  17 LNAFVTVFFDEALAQAAAADKQRAAGDPKGPLHGVPIAVKDNIDVKGVPTTAGSKALENYPAPYDATVVERLRKAGAVIL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  117 GKTNLDEFAMGSGSTDGIFGPVKNPWsyskqyrekrkqnphskneDSDW-----------LItggssggsaaavSAFTCY 185
Cdd:pfam01425  97 GKTNMDEFAMGSSTENSVFGPTRNPW-------------------DLSRtpggssggsaaAV------------AAGLVP 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  186 AALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAGPDPKDSTTVhDPINKP 265
Cdd:pfam01425 146 LAIGTDTGGSIRIPASFCGLVGLKPTYGRVSRYGVVGYASSLDQVGPLARSVEDAALLLRVISGYDPKDSTSL-PPPVPD 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  266 FMLPSLADVSKLCIGIPKEYLIPELSSEVRSLWSKAADLFESEGAKVLEVSLPHTSYSIVCYHVLCTSEVASNMARFDGl 345
Cdd:pfam01425 225 YAEPVKKSLKGLRIGVYREDGYFDLDPEVRRAVEEALAQLEALGHEVVEVDPPSLDYALPLYYLIAPAEASSNLARYDG- 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  346 qyghRCDINVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFVNAFNSgVDVLLTPTTLS 425
Cdd:pfam01425 304 ----VPSGPDDLSELYPRTRAEGLGDEVKRRIILGNYALSAGYYDKYYLKAQKVRRLIRREFAGLFEE-LDVLLSPTAPT 378

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 383873113  426 EAVPYLEFikEDNRTRSAQDDIFTQA---VNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLL 488
Cdd:pfam01425 379 PAPRLGEP--DDSPLVMYNLDDFTAGvvpVNLAGLPAISLPAGFTADGLPVGVQIIGKPGDEETLL 442
PRK07139 PRK07139
amidase; Provisional
 75-496 3.42e-76

amidase; Provisional


Pssm-ID: 235945 [Multi-domain]  Cd Length: 439  Bit Score: 246.88  E-value: 3.42e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  75 VKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWSYSKQYREKRKQ 154
Cdd:PRK07139  44 IKDNFATSEGPTHASSKSLENFKPSYNATVVQKLINAGAKPVAKVHCDELGLGGTGLFSAFGLIKNPLDSSKLVGGSSSG 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 155 NPHSKNEDSDWlitggssggsaaavsaftcyaALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILT 234
Cdd:PRK07139 124 SAATFNKNISF---------------------AIGSDTGDSVRLPASFIGKVGFKPSYGAISRYGLFAYASSLDTVAYFT 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 235 RCVDDAAIVLGALAGPDPKDSTTVHDPIN-----KPFMLPSLaDVSKlcigipkeylipELSSEVRSLWSKAADLFESEG 309
Cdd:PRK07139 183 HNVNDAIILSKVLFGKDENDLTSVDVKINnvkktKPKKVAYL-DCFK------------ELEEYVAKKYKKLINILKSEN 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 310 AKVLEVSLPH-------TSYSIVCYhvlctSEVASNMARFDGLQYGHRCDiNVSTEAMYAATRREGFNDVVRGRILSGNF 382
Cdd:PRK07139 250 IEVEKIKIDEkllkaikPVYKIISY-----SEASSNLANLNGIAFGNREK-GSSWEEIMINTRSEGFGKMVQKRLILGSY 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 383 FLLKENYENYFVKAQKVRRLIANDFVNAFNSgVDVLLTPTTLSEAvPYLEFIKEDNrtRSAQDDIFTQAvNMAGLPAVSI 462
Cdd:PRK07139 324 FLEEENQEKYFLKAKKVRRVIKNYYESIHNK-FDIVIYPAYADIA-PDIDENENKS--DNYMDYILTIS-NLVGNPSLSI 398

                        410       420       430
                 ....*....|....*....|....*....|....
gi 383873113 463 PVAlSNQGLPIGLQFIGRAFCDQQLLTVAKWFEK 496
Cdd:PRK07139 399 PLG-KYNNLPFNLAIDSKIYDDEKLLSYSLYIEE 431
 
Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 1-496 3.42e-163

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 471.56  E-value: 3.42e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   1 MLGRTLQEVSAALKQGQITPTELCQKCLSLIKKT-KFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNF 79
Cdd:COG0154    4 LAELSAAELAAALRAGEVSAVELVEAALARIEAVnPALNAFVTVDAERALAEARAADARRAAGEALGPLAGVPVAVKDLI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  80 STSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWsyskqyrekrkqNPHsk 159
Cdd:COG0154   84 DVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPW------------DPDrt 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 160 nedsdwlitggssggSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDD 239
Cdd:COG0154  152 pgg--------ssggSAAAVAAGLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVAD 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 240 AAIVLGALAGPDPKDSTTVHDPInKPFMLPSLADVSKLCIGIPKEYLIPE-LSSEVRSLWSKAADLFESEGAKVLEVSLP 318
Cdd:COG0154  224 AALLLDVLAGPDPRDPTSAPAPV-PDYLAALDRDLKGLRIGVPREYFGGDgVDPEVAAAVEAAAAALEALGAEVVEVDLP 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 319 HTSYSIVCYHVLCTSEVASNMArfdglqyghrcdinvsteAMYaATRREGFNDVVRGRILSGNFFllkenYENYFVKAQK 398
Cdd:COG0154  303 DLDEALAAYYTIAAAEAAANLA------------------DLL-RTRPEGFGPEVRRRILLGAYY-----SAADYLKAQR 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 399 VRRLIANDFVNAFNsGVDVLLTPTTLSEAVPYLEFIKEDN--RTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQ 476
Cdd:COG0154  359 VRALLRRDFAAAFE-DYDVLLTPTTPTPAPPIGELDADIDpaLAMNYLLDRFTAPANLAGLPALSVPAGFTADGLPVGLQ 437

                        490       500
                 ....*....|....*....|
gi 383873113 477 FIGRAFCDQQLLTVAKWFEK 496
Cdd:COG0154  438 LIGPPGDEATLLRLAAALEQ 457
gatA TIGR00132
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase ...
 11-496 2.98e-158

aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase is missing. tRNA(Gln) is misacylated with Glu after which a heterotrimeric amidotransferase converts Glu to Gln. This model represents the amidase chain of that heterotrimer, encoded by the gatA gene. In the Archaea, Asn--tRNA ligase is also missing. This amidase subunit may also function in the conversion of Asp-tRNA(Asn) to Asn-tRNA(Asn), presumably with a different recognition unit to replace gatB. Both Methanococcus jannaschii and Methanobacterium thermoautotrophicum have both authentic gatB and a gatB-related gene, but only one gene like gatA. It has been shown that gatA can be expressed only when gatC is also expressed. In most species expressing the amidotransferase, the gatC ortholog is about 90 residues in length, but in Mycoplasma genitalium and Mycoplasma pneumoniae the gatC equivalent is as the C-terminal domain of a much longer protein. Not surprisingly, the Mycoplasmas also represent the most atypical lineage of gatA orthology. This orthology group is more narrowly defined here than in Proc Natl Acad Aci USA 94, 11819-11826 (1997). In particular, a Rhodococcus homolog found in association with nitrile hydratase genes and described as an enantiomer-selective amidase active on several 2-aryl propionamides, is excluded here. It is likely, however, that the amidase subunit GatA is not exclusively a part of the Glu-tRNA(Gln) amidotransferase heterotrimer and restricted to that function in all species. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272925 [Multi-domain]  Cd Length: 460  Bit Score: 458.73  E-value: 2.98e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   11 AALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRykngqSLGDLDGIPVAVKDNFSTSGIETTCA 89
Cdd:TIGR00132   3 QLLKKKEISIKEVLEASLDRIEANKdKINAFLEVTVEKALKQAKKLDKA-----ILTPLAGIPIAVKDNISTKGIVTTCA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   90 SNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWsyskqyrekrkqnphskNEDsdwLITG 169
Cdd:TIGR00132  78 SKILENYIPPYDATVIERLKQAGALIIGKTNMDEFAMGSSTETSAFGPTKNPW-----------------NLD---RVPG 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  170 GSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAG 249
Cdd:TIGR00132 138 GSSGGSAAAVAADLAPFSLGSDTGGSIRQPASFCGVVGFKPTYGRVSRYGLVAYASSLDQIGPFARTVEDIALLLDVISG 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  250 PDPKDSTTVHDPInkPFMLPSLADVSK-LCIGIPKEyLIPELSSEVRSLWSKAADLFESEGAKVLEVSLPHTSYSIVCYH 328
Cdd:TIGR00132 218 HDKRDSTSAKVPD--PEFFEELKKDLKgLKVGVVKE-FSEEMDKEVQEKFENALEVLEELGAEIVEVSFPHVKYALPIYY 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  329 VLCTSEVASNMARFDGLQYGHRCDINVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFV 408
Cdd:TIGR00132 295 IISPSEASSNLARYDGIRYGYRIEEPNSLKELYAKTRAEGFGEEVKRRIMLGNYALSAGYYDKYYLKAQKVRTLIIDDFL 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  409 NAFnSGVDVLLTPTTlseavPYLEFI---KEDNRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQ 485
Cdd:TIGR00132 375 KLF-EEVDVIVSPTA-----PTLPFKigeKLDDPLEMYLSDILTVPANLAGLPAISVPCGVKEKGLPIGLQIIGKCFDDK 448

                         490
                  ....*....|.
gi 383873113  486 QLLTVAKWFEK 496
Cdd:TIGR00132 449 TLLQVSYAFEQ 459
Amidase pfam01425
Amidase;
37-488 2.74e-133

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 394.36  E-value: 2.74e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   37 LNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLM 116
Cdd:pfam01425  17 LNAFVTVFFDEALAQAAAADKQRAAGDPKGPLHGVPIAVKDNIDVKGVPTTAGSKALENYPAPYDATVVERLRKAGAVIL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  117 GKTNLDEFAMGSGSTDGIFGPVKNPWsyskqyrekrkqnphskneDSDW-----------LItggssggsaaavSAFTCY 185
Cdd:pfam01425  97 GKTNMDEFAMGSSTENSVFGPTRNPW-------------------DLSRtpggssggsaaAV------------AAGLVP 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  186 AALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAGPDPKDSTTVhDPINKP 265
Cdd:pfam01425 146 LAIGTDTGGSIRIPASFCGLVGLKPTYGRVSRYGVVGYASSLDQVGPLARSVEDAALLLRVISGYDPKDSTSL-PPPVPD 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  266 FMLPSLADVSKLCIGIPKEYLIPELSSEVRSLWSKAADLFESEGAKVLEVSLPHTSYSIVCYHVLCTSEVASNMARFDGl 345
Cdd:pfam01425 225 YAEPVKKSLKGLRIGVYREDGYFDLDPEVRRAVEEALAQLEALGHEVVEVDPPSLDYALPLYYLIAPAEASSNLARYDG- 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  346 qyghRCDINVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFVNAFNSgVDVLLTPTTLS 425
Cdd:pfam01425 304 ----VPSGPDDLSELYPRTRAEGLGDEVKRRIILGNYALSAGYYDKYYLKAQKVRRLIRREFAGLFEE-LDVLLSPTAPT 378

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 383873113  426 EAVPYLEFikEDNRTRSAQDDIFTQA---VNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLL 488
Cdd:pfam01425 379 PAPRLGEP--DDSPLVMYNLDDFTAGvvpVNLAGLPAISLPAGFTADGLPVGVQIIGKPGDEETLL 442
PRK07139 PRK07139
amidase; Provisional
 75-496 3.42e-76

amidase; Provisional


Pssm-ID: 235945 [Multi-domain]  Cd Length: 439  Bit Score: 246.88  E-value: 3.42e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  75 VKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWSYSKQYREKRKQ 154
Cdd:PRK07139  44 IKDNFATSEGPTHASSKSLENFKPSYNATVVQKLINAGAKPVAKVHCDELGLGGTGLFSAFGLIKNPLDSSKLVGGSSSG 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 155 NPHSKNEDSDWlitggssggsaaavsaftcyaALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILT 234
Cdd:PRK07139 124 SAATFNKNISF---------------------AIGSDTGDSVRLPASFIGKVGFKPSYGAISRYGLFAYASSLDTVAYFT 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 235 RCVDDAAIVLGALAGPDPKDSTTVHDPIN-----KPFMLPSLaDVSKlcigipkeylipELSSEVRSLWSKAADLFESEG 309
Cdd:PRK07139 183 HNVNDAIILSKVLFGKDENDLTSVDVKINnvkktKPKKVAYL-DCFK------------ELEEYVAKKYKKLINILKSEN 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 310 AKVLEVSLPH-------TSYSIVCYhvlctSEVASNMARFDGLQYGHRCDiNVSTEAMYAATRREGFNDVVRGRILSGNF 382
Cdd:PRK07139 250 IEVEKIKIDEkllkaikPVYKIISY-----SEASSNLANLNGIAFGNREK-GSSWEEIMINTRSEGFGKMVQKRLILGSY 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 383 FLLKENYENYFVKAQKVRRLIANDFVNAFNSgVDVLLTPTTLSEAvPYLEFIKEDNrtRSAQDDIFTQAvNMAGLPAVSI 462
Cdd:PRK07139 324 FLEEENQEKYFLKAKKVRRVIKNYYESIHNK-FDIVIYPAYADIA-PDIDENENKS--DNYMDYILTIS-NLVGNPSLSI 398

                        410       420       430
                 ....*....|....*....|....*....|....
gi 383873113 463 PVAlSNQGLPIGLQFIGRAFCDQQLLTVAKWFEK 496
Cdd:PRK07139 399 PLG-KYNNLPFNLAIDSKIYDDEKLLSYSLYIEE 431
PRK07488 PRK07488
indoleacetamide hydrolase;
5-496 1.96e-72

indoleacetamide hydrolase;


Pssm-ID: 236030 [Multi-domain]  Cd Length: 472  Bit Score: 237.95  E-value: 1.96e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   5 TLQEVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYKNGQSLGdLDGIPVAVKDNFSTSGI 84
Cdd:PRK07488  12 SLTEAAAALRSGRLSCLELVEALLARAAALAPLNAFTTVDAEGALAAARRIDAQRAAGAALL-LAGVPIVIKDNINTAGM 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  85 ETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWSYSkqyrekrkqnphsknedsd 164
Cdd:PRK07488  91 PTTAGTPALLGFVPATDAPVVQRLLDAGAVPLGKANMHELAFGITSNNGAFGAVRNPYDPA------------------- 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 165 wLITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVL 244
Cdd:PRK07488 152 -RIAGGSSGGTAAAVAARLAPAGLGTDTGGSVRIPAALCGVVGLRPTVGRYSGDGVVPISHTRDTVGPIARSVADLALLD 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 245 GALAGPDPkdsttvhdpinkpfmLPSLADVSKLCIGIPKEYLIPELSSEVRSLWSKAADLFESEGAKVLEVSLPH----- 319
Cdd:PRK07488 231 AVITGDAA---------------LPAPVALAGLRLGVPAAPFWDGLDPDVAAVAEAALAKLAAAGVTFVELDLPGlheln 295

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 320 --TSYSIVCYHvlctsevasnmARFDGLQYGHRCDINVSTEAMYAATR----REGFNDVVRGRILSGnffllkenyENYF 393
Cdd:PRK07488 296 eaVGFPIALYE-----------ALADLRAYLRENGAGVSFEELVARIAspdvRAIFRDLLDPPQISE---------DAYR 355

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 394 VKAQKVRRLIANDFVNAF-NSGVDVLLTPTTLSEAVPylefIKEDNRT--RSAQDDIFTQAV-NM-----AGLPAVSIPV 464
Cdd:PRK07488 356 AALDVGRPRLQAWYRQAFaRHGLDAILFPTTPLTAPP----IGDDDTVilNGAAVPTFARVIrNTdpasnAGLPGLSLPA 431

                        490       500       510
                 ....*....|....*....|....*....|..
gi 383873113 465 ALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEK 496
Cdd:PRK07488 432 GLTPHGLPVGLELDGPAGSDRRLLAIGRALER 463
PRK07235 PRK07235
amidase; Provisional
 62-498 1.09e-61

amidase; Provisional


Pssm-ID: 235979 [Multi-domain]  Cd Length: 502  Bit Score: 210.63  E-value: 1.09e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  62 GQSLGDLDGIPVAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNP 141
Cdd:PRK07235  82 GAAEGKLAGKTVALKDNVAVAGVPMMNGSSTLEGFVPSFDATVVTRLLDAGATIVGKATCEDLCFSGGSHTSDPGPVHNP 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 142 WsyskqyrekrkqNP-HSKNEDSdwlitggssGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGL 220
Cdd:PRK07235 162 R------------DPgYSAGGSS---------SGSAALVAAGEVDMAIGGDQGGSIRIPSAWCGIYGMKPTHGLVPYTGA 220

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 221 IPLVNSMDVPGILTRCVDDAAIVLGALAGPDPKDSTTVHDPINKPFMLPSLADVSKLCIGIPKE-YLIPELSSEVRSLWS 299
Cdd:PRK07235 221 FPIERTIDHLGPMTATVRDNALLLEVIAGRDGLDPRQPAQPPVDDYTAALDRGVKGLKIGILREgFGLPNSEPEVDEAVR 300

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 300 KAADLFESEGAKVLEVSLPHTSYSIVCYHVLCTSEVASNMARFDGlqYGHRCDINVSTEAM--YAATRRE---GFNDVVR 374
Cdd:PRK07235 301 AAAKRLEDLGATVEEVSIPLHRLALAIWNPIATEGATAQMMLGNG--YGFNWKGLYDTGLLdaFGAGWREradDLSETVK 378

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 375 GRILSGNFFLlkENYEN-YFVKAQKVRRLIANDFVNAFNSgVDVLLTPTTLSEAVPYLEfikednrTRSAQDDIFTQAVN 453
Cdd:PRK07235 379 LVMLLGQYGL--ERYHGrYYAKARNLARRLRAAYDEALRK-YDLLVMPTTPMVATPLPA-------PDASREEYVSRALE 448

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....
gi 383873113 454 M---------AGLPAVSIPVALSNqGLPIGLQFIGRAFCDQQLLTVAKWFEKQV 498
Cdd:PRK07235 449 MiantapfdvTGHPAMSVPCGLVD-GLPVGLMLVGRHFDEATILRAAAAFEASG 501
PRK09201 PRK09201
AtzE family amidohydrolase;
5-505 5.86e-57

AtzE family amidohydrolase;


Pssm-ID: 236409 [Multi-domain]  Cd Length: 465  Bit Score: 197.11  E-value: 5.86e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   5 TLQEVSAALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNFSTSG 83
Cdd:PRK09201   8 SAAEIAAAVRAGELSARAVAQATLARIARANpQLNAFTAVTAERALAEAARIDAARAAGEPLGPLAGVPFAVKNLFDVAG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  84 iETTCASNMLKGYIPP--YNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPwsyskqyrekrkqnpHSKNE 161
Cdd:PRK09201  88 -LTTLAGSKINRDRPPatRDATAVRRLEAAGAVLVGALNMDEYAYGFTTENSHYGATRNP---------------HDLTR 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 162 dsdwlITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAA 241
Cdd:PRK09201 152 -----IAGGSSGGSAAAVAAGLVPFTLGSDTNGSIRVPASLCGIFGLKPTYGRLSRAGSFPFVASLDHIGPFARSVADLA 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 242 IVLGALAGPDPKDSTTVHDPINKpfMLPSL-ADVSKLCIGIPKEYLIPELSSEVRSLWSKAADLFESEGakvlEVSLPHT 320
Cdd:PRK09201 227 LVYDVLQGPDPQDPFQADRPAEP--TAPLLdRGAEGLRIAVLGGYFAQWADPEARAAVDRVAKALGATR----EVELPEA 300

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 321 SYSIVCYHVLCTSEVASNmarfdglqygHRCDInvsteamyaATRREGFNDVVRGRILSGnfFLLKenyENYFVKAQKVR 400
Cdd:PRK09201 301 ARARAAAFIITASEGGNL----------HLPAL---------RTRPQDFDPASRDRLLAG--AMLP---AAWYVQAQRFR 356

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 401 RLIANDFVNAFNSgVDVLLTPTTLSEAvPYL--EFIKEDNRTRSAQDD--IFTQAVNMAGLPAVSIPVALSNqGLPIGLQ 476
Cdd:PRK09201 357 RWFRQAVLELFEH-VDVLIAPATPCSA-PLIgqETMRIDGVELPVRANlgILTQPISFIGLPVVAVPLRTPG-GLPIGVQ 433

                        490       500       510
                 ....*....|....*....|....*....|.
gi 383873113 477 FIGRAFCDQQLLTVAKWFEKQ--VQFPVIQL 505
Cdd:PRK09201 434 LIAAPWREDLALRAAAALEQQgvAAAPVPTV 464
PRK06169 PRK06169
putative amidase; Provisional
 5-496 1.59e-53

putative amidase; Provisional


Pssm-ID: 180437 [Multi-domain]  Cd Length: 466  Bit Score: 187.92  E-value: 1.59e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   5 TLQEVSAALKQGQITPTELCQKCLSLIKK-TKFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNFSTSG 83
Cdd:PRK06169   8 TAVELLAAYRRGELSPVEATQAVLDRIDRrDPAVNAFCLVDAEGALAAARASEERWRRGEPCGLLDGVPVSIKDIFLTRG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  84 IETTCASNMLKGYIP-PYNATVVQKLLDQGALLMGKTNLDEFAMgSGSTDG-IFGPVKNPWSYSKqyrekrkqNPHSKNE 161
Cdd:PRK06169  88 WPTLRGSRAIDADGPwDVDAPAVARLREAGAVLLGKTTTPEFGW-KGVTDSpLYGITRNPWDTRL--------TAGGSSG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 162 DSdwlitggssggsaaavsafTCYAAL-------GSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLvNSMDVPGILT 234
Cdd:PRK06169 159 GA-------------------AAAVALgmgplsvGTDGGGSVRIPASFCGTFGFKPTFGRVPLYPASPF-GTLAHVGPMT 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 235 RCVDDAAIVLGALAGPDPKDSTTVHdPINKPFMLPSLADVSKLCIGIPKEYLIPELSSEVRSLWSKAADLFESEGAKVLE 314
Cdd:PRK06169 219 RTVADAALLLDVIARPDARDWSALP-PPTTSFLDALDRDVRGLRIAYSPTLGYVDVDPEVAALVAQAVQRLAALGARVEE 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 315 VSLPHTSySIVCYHVLCTSEVASNMARFdGLQYGHRCDinvsteamyaatrrEGFNDVV-RGRILSGNFFLlkenyenyf 393
Cdd:PRK06169 298 VDPGFSD-PVEAFHVLWFAGAARLLRAL-PPGQRALLD--------------PGLRRIAeRGATYSASDYL--------- 352

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 394 vKAQKVRR-LIANdfVNAFNSGVDVLLTPTtlseaVPYLEF-IKEDNRTRSAQDDI-----FTQAVNMAGLPAVSIPVAL 466
Cdd:PRK06169 353 -DATAVRAaLGAR--MGAFHERYDLLLTPT-----LPIPAFeAGHDVPPGSGLTDWtqwtpFTYPFNLTQQPAASVPCGF 424

                        490       500       510
                 ....*....|....*....|....*....|
gi 383873113 467 SNQGLPIGLQFIGRAFCDQQLLTVAKWFEK 496
Cdd:PRK06169 425 TAAGLPVGLQIVGPRHSDDLVLRVARAYEQ 454
PRK08186 PRK08186
allophanate hydrolase; Provisional
 1-504 1.15e-52

allophanate hydrolase; Provisional


Pssm-ID: 236177 [Multi-domain]  Cd Length: 600  Bit Score: 188.51  E-value: 1.15e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   1 MLGRTLQEVSAALKQGQITPTELCQKCLSLIKKTKFLNAYIT-VSEEVALKQAEESEKRYkngQSLGDLDGIPVAVKDNF 79
Cdd:PRK08186   4 PTDLTLASLRAAYRAGTLTPRAVVAALYARIAAVDDPEVWIHlRPEADLLAQAAALEARD---PAALPLYGVPFAVKDNI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  80 STSGIETTCASNMLkGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWsyskqyrekrkqnphsk 159
Cdd:PRK08186  81 DVAGLPTTAACPAF-AYTPERDATVVARLRAAGAIVIGKTNLDQFATGLVGTRSPYGAVRNAF----------------- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 160 neDSDwlitggssggsaaavsaftcY-------------------AALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGL 220
Cdd:PRK08186 143 --DPE--------------------YvsggsssgsavavalglvsFALGTDTAGSGRVPAAFNNIVGLKPTLGLLSTRGV 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 221 IPLVNSMDVPGILTRCVDDAAIVLGALAGPDPKDSTTVHDPINKPFMLPsladvSKLCIGIP-KEYLIPELSSEVRSLWS 299
Cdd:PRK08186 201 VPACRTLDCVSVFALTVDDADAVLAVMAGFDPADPYSRANPADAPAALP-----AGPRVGVPrAAQLEFFGDAEAEAAFA 275

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 300 KAADLFESEGAKVLEVslphtsysivcyhvlctsevasnmarfdglqyghrcDINVSTEAM------------YAA---- 363
Cdd:PRK08186 276 AALARLEALGAELVEI------------------------------------DFSPFLEAArllyegpwvaerYAAvgef 319

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 364 --TRREGFNDVVRGRILSGNFF----LLKENYenyfvKAQKVRRLIANDFvnafnSGVDVLLTPTTlsEAVPYLEFIKED 437
Cdd:PRK08186 320 leAHPDAVDPVVRGIIAGAAAFsaadAFRALY-----RLAELRRAAEAVL-----AGIDALLVPTA--PTHPTIAEVAAD 387

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 383873113 438 NRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQFPVIQ 504
Cdd:PRK08186 388 PIGLNSRLGTYTNFVNLLDLCALAVPAGFRADGLPFGVTLIAPAFADQALADLAARLQAALALPLGG 454
PRK07042 PRK07042
amidase; Provisional
 8-495 1.85e-52

amidase; Provisional


Pssm-ID: 235915 [Multi-domain]  Cd Length: 464  Bit Score: 184.79  E-value: 1.85e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   8 EVSAALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNFSTSGIET 86
Cdd:PRK07042  11 ELLAGYRARSLSPVEVTEAVLAHIARWEpHLNALYAFDPEAARAAARASTARWAKGEPLGPLDGVPVTIKENIATRGVPV 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  87 T--CASNMLKgyIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWSYSkqyrekrkQNPHSKNEDSD 164
Cdd:PRK07042  91 PlgTAATDLP--PAAADAPPAARLREAGAVILAKTTMPDYGMLSSGLSSFHGLTRNPWDLD--------QNPGGSSAGAG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 165 wlitggssggsaaavsaftcyAA---------LGSDTGGSTRNPAAHCGLVGFKPSyglvsrHGLIPLvnsmDVP----- 230
Cdd:PRK07042 161 ---------------------AAaaagygplhLGTDIGGSVRLPAGWCGIVGLKPS------LGRIPI----DPPytgrc 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 231 -GILTRCVDDAAIVLGALAGPDPKDSTTVhdPINkPFMLPSLA-DVSKLCIGIpkeYLIP----ELSSEVRSLWSKAADL 304
Cdd:PRK07042 210 aGPMTRTVDDAALLMSVLSRPDARDGTSL--PPQ-DIDWSDLDiDVRGLRIGL---MLDAgcglAVDPEVRAAVEAAARR 283

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 305 FESEGAKVLEVSLphtsysivcyhVLctsevasNMARFDGLQ--YGHRC--DInvsteamyaatrrEGFNDVVRGRILSg 380
Cdd:PRK07042 284 FEAAGAIVEPVPP-----------FL-------TRAMLDGLDrfWRARLwsDL-------------AALPPERRAKVLP- 331

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 381 nffllkenyenYFVK-AQKVRRLIANDFVNAFN-------------SGVDVLLTPTTLSEAVPyLEFIKEDNRTRSAQDD 446
Cdd:PRK07042 332 -----------YIRRwAEGGADLSGVEAVRGFNqtfamraaaarlfAEFDYVLSPVAPVPAFP-AEWASPTNDPARPFEH 399

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|
gi 383873113 447 I-FTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFE 495
Cdd:PRK07042 400 IaFTVPWNMSEQPAASINCGFTRDGLPIGLQIVGPRFDDLGVLRLAKAFE 449
PRK06170 PRK06170
amidase; Provisional
 4-495 2.86e-51

amidase; Provisional


Pssm-ID: 235723 [Multi-domain]  Cd Length: 490  Bit Score: 182.16  E-value: 2.86e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   4 RTLQEVSAALKQGQITPTELCQKCLSLIKK-TKFLNAYITVSEEVALKQAEESEKRYKNGQsLGDLDGIPVAVKDNFSTS 82
Cdd:PRK06170  12 LPATELAAALAAGEVSSVELTDLAIARIERhDGKINAIVVRDFDRARAAARAADAARARGE-RGPLLGIPVTVKESFNVA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  83 GIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWSYSKqyrekrkqNPHSKNED 162
Cdd:PRK06170  91 GLPTTWGFPDLRDYVPAEDAVAVARLKAAGAVILGKTNVPLGLQDWQSYNEIYGTTNNPWDLAR--------TPGGSSGG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 163 SdwlitggssggSAAAVSAFTcYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVN-------SMDVPGILTR 235
Cdd:PRK06170 163 S-----------AAALAAGFG-ALSIGSDIGGSLRVPAHYCGVYAHKPTLGLVPLRGHIPPPApalpgqaDLAVAGPMAR 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 236 CVDDAAIVLGALAGPDPKDsttvhDPINKPFMLP-----SLADVSKLCIgiPKEYLIPeLSSEVRSLWSKAADLFESEGA 310
Cdd:PRK06170 231 SARDLALLLDVMAGPDPLD-----GGVAYRLALPparhgRLKDFRVLVL--DEHPLLP-TDAAVRAAIERLAAALADAGA 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 311 KVLEVS--LPHTSysiVCYHVLCTSEVASNMARFDGLQYGhrcdiNVSTEAM--------YAATRRegfndvvRGRILSG 380
Cdd:PRK06170 303 RVVRHSplLPDLA---ESARLYMRLLFAASAARFPPDAYA-----DAQARAAglsaddrsLAAERL-------RGAVLSH 367

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 381 NFFLLkenyenyfvkAQKVRRLIANDFVNAFNSgVDVLLTPTTLSEAVPYLEFIKEDNRTRS---AQDDIFTQAV----- 452
Cdd:PRK06170 368 RDWLF----------ADAAREELRAAWRRFFAE-FDVVLCPVTPTPAFPHDHAPDPLERRIDidgVSYPYWDQLVwagla 436

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|...
gi 383873113 453 NMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFE 495
Cdd:PRK06170 437 TLPGLPATAIPIGLSATGLPVGVQIVGPALEDRTPLRLAELLE 479
PRK08137 PRK08137
amidase; Provisional
 5-499 1.24e-46

amidase; Provisional


Pssm-ID: 236161 [Multi-domain]  Cd Length: 497  Bit Score: 169.95  E-value: 1.24e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   5 TLQEVSAALKQGQITPTELCQKCLSLIKKTK----FLNAYITVSEEvALKQAEESEKRYKNGQSLGDLDGIPVAVKDNF- 79
Cdd:PRK08137   7 RAGALQAAMPAGAAPASQLTRAYLQRIARIDrdgpRLNAVIELNPD-AEADAAALDAERKAGKVRGPLHGIPVLLKDNId 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  80 STSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFA-----MGSGSTDGIFGPVKNPwsyskqYREKRkq 154
Cdd:PRK08137  86 AADPMPTTAGSLALAGNRPTRDAFLVARLRDAGAVILGKANLSEWAnfrstRSSSGWSARGGLTRNP------YALDR-- 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 155 NPHSKNEDSDWLITGGSSGgsaaavsaftcyAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILT 234
Cdd:PRK08137 158 SPCGSSSGSGAAVAAGLAA------------VAIGTETDGSITCPAAINGLVGLKPTVGLVSRDGIVPISHSQDTAGPMT 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 235 RCVDDAAIVLGALAGPDPKDSTTVHDPINKPFMLPSL-ADVSK-LCIGIPKEYLipELSSEVRSLWSKAADLFESEGAKV 312
Cdd:PRK08137 226 RTVADAAAVLTAIAGGDPADPATASAPAPAVDYVAALdADALRgARLGVARNYL--GYHPEVDAQFERALAELKAAGAVV 303

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 313 LEVSLP-HTSYSIVCYHVLCTsEVASNMArfdglQYGHRCDINVSTEAMYAATrreGFNDVVRGRILS--GNFFLLKENY 389
Cdd:PRK08137 304 IDVVDLdDGDWGEAEKVVLLH-EFKAGLN-----AYLRSTAPHAPVRTLADLI---AFNRAQHAREMPyfGQELFEQAQA 374

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 390 EN------YFVKAQKVRRLIANDFVNAF--NSGVDVLLTPTTlSEAVPyLEFIKEDNRTRSaqddiFTQAVNMAGLPAVS 461
Cdd:PRK08137 375 APglddpaYLDALADAKRLAGPEGIDAAlkEHRLDALVAPTT-GPAWL-IDLINGDSFGGS-----SSTPAAVAGYPHLT 447

                        490       500       510
                 ....*....|....*....|....*....|....*...
gi 383873113 462 IPVALSnQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQ 499
Cdd:PRK08137 448 VPMGQV-QGLPVGLSFIGAAWSEARLLELGYAYEQATH 484
PRK06102 PRK06102
amidase;
3-491 2.70e-43

amidase;


Pssm-ID: 235698 [Multi-domain]  Cd Length: 452  Bit Score: 159.81  E-value: 2.70e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   3 GRTLQEVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNFSTS 82
Cdd:PRK06102   5 AKSAAQLAVLIQSGALDPVQVAEQALDAIASYADQAVFISLTEERAMREAEASSARWRAGRSLGLLDGIPIAWKDLFDVA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  83 GIETTCASNMLKGYIPP-YNATVVQKLLDQGALLMGKTNLDEFAMgSGStdGIfgpvkNPwsyskQYREKRkqNPHSKNE 161
Cdd:PRK06102  85 GSVTTAGSVVLANAAPAsRDAAVVALLARAGMVSIGRTNMSEFAF-SGL--GL-----NP-----HYGTPV--NPRSTDV 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 162 DSdwlITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAA 241
Cdd:PRK06102 150 PR---IPGGSSSGSAVAVAAGLVPVAMGTDTGGSVRIPAAFNGLVGYKATRGRYSMDGVFPLAKSLDSLGPLCRSVRDAV 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 242 IVLGALAGPDPKDSTTVhdpinkpfmlpSLADVSKLcigIPKEYLIPELSSEVRSLWSKAADLFESEGAKVLEVSLP--H 319
Cdd:PRK06102 227 WIDAAMRGLTAPDVVRR-----------PLAGLRLV---VPETVVFDDAEPGVRAAFEAAVERLQAAGALVERQAFPafQ 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 320 TSYSIVCYH-VLCTSEV-ASNMARFDG---LQYGHRcdinvsteamyaatrregfndvVRGRILSGNFFLLkenyENYFV 394
Cdd:PRK06102 293 EILDLIARHgWLVTAEAfALHQERLDGpdaARMDPR----------------------VVKRTRLGRKITA----SDYIA 346

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 395 KAQKVRRLIAndfvnAFNSGVD--VLLTPTTLSEAvPYLEFIKEDnrtrsaqDDIFTqAVNMAGL-----------PAVS 461
Cdd:PRK06102 347 LLEARERLIA-----QVTRELGgaLLATPTVAHVA-PPLAPLEAD-------DDLFF-ATNLKTLrntmpgnfldmCGVS 412

                        490       500       510
                 ....*....|....*....|....*....|
gi 383873113 462 IPVALSNQGLPIGLQFIGRAFCDQQLLTVA 491
Cdd:PRK06102 413 LPCGTGAAGMPVGLLLSAPAGRDERLLRAA 442
PRK06828 PRK06828
amidase; Provisional
 5-498 3.42e-43

amidase; Provisional


Pssm-ID: 180715 [Multi-domain]  Cd Length: 491  Bit Score: 160.37  E-value: 3.42e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   5 TLQEVSAALKQGQITPTELCQKCLSLI----KKTKFLNAYITVS-EEVALKQAEESEKRYKNgqSLGDLDGIPVAVKDNF 79
Cdd:PRK06828  14 TIHDIQTAMEDGKLTSKELVMYYLHRIakydQDGPKINSILEINpDAIFIAEALDHERKIKG--VRGPLHGIPVLLKDNI 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  80 STSG-IETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMgsgstdgiFGPVKNPWSYSKqyREKRKQNPHS 158
Cdd:PRK06828  92 ETNDsMHTSAGTIALEQHISSEDAFLVTKLREAGAVILGKANMTELAN--------FMSFEMWAGYSA--RGGQTINPYG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 159 KNEDsDWLITGGSSGGSAAAVSAFTCyAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVD 238
Cdd:PRK06828 162 TGED-DMFVGGSSTGSAIAVAANFTV-VSVGTETDGSILSPAVQNSVVGIKPTVGLISRRGIIPFTYSQDTAGPFARTVT 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 239 DAAIVLGALAGPDPKDSTTVHDPINKPFMLPSLADVSKLC---IGI----PKEYLipELSSEVRSLWSKAADLFESEGAK 311
Cdd:PRK06828 240 DAAILLGSLTGVDEKDVVTHKSEGIAEHDYTKYLDANGLNgakIGVynnaPKEYY--ESGEYDEKLFKETIEVLRSEGAT 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 312 VLE-VSLP--HTSYSIvcyHVLcTSEVASNMARF----------DGLQYGHRCDINVSTEAM-YAATRREGFNDVvrGRI 377
Cdd:PRK06828 318 VVEdIDIPsfHREWSW---GVL-LYELKHSLDNYlsklpstipvHSISELMEFNENIAERALkYGQTKLERRKDF--PNT 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 378 LSGNFFLLKENYENYFVKAQKVrrlianDFVNAfNSGVDVLLTPTTLSEAVPylefikednrtrsaqddiftqavNMAGL 457
Cdd:PRK06828 392 LRNPEYLNARLEDIYFSQEQGI------DFALE-KYNLDAILFPSYIGSTIC-----------------------AKAGY 441

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|.
gi 383873113 458 PAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQV 498
Cdd:PRK06828 442 PSIAIPAGYMEGGRPFGITLASTAFSEGTLIKLAYAFEQAT 482
PRK07056 PRK07056
amidase; Provisional
 5-499 3.71e-42

amidase; Provisional


Pssm-ID: 235921 [Multi-domain]  Cd Length: 454  Bit Score: 156.64  E-value: 3.71e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   5 TLQEVSAALKQGQITPTELCQKCLSLI--KKTKFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNFSTS 82
Cdd:PRK07056   7 TLAALAADLAAGRTTSRALVEAALARIadPAGEGARVFTHVDADAARAAADAADALRAAGAAPSPLAGIPVSVKDLFDVA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  83 GIETTCASNMLKGYIP-PYNATVVQKLLDQGALLMGKTNLDEFAMgSGStdGI---FGPVKNPWSYSKQyrEKRkqnphs 158
Cdd:PRK07056  87 GQVTRAGSRVLADAPPaAADAPAVARLRRAGAVLIGRTNMTEFAF-SGL--GLnphYGTPRNPWRRDVG--DGR------ 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 159 knedsdwlITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVD 238
Cdd:PRK07056 156 --------IPGGSSSGAAVSVADGMAAAALGTDTGGSIRIPAALCGLTGFKPTARRVPLQGAVPLSTTLDSIGPLARSVA 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 239 DAAIVLGALAGPDPKDsttvhdpinkpfmlPSLADVSKLCIGIPKEYLIPELSSEVRSLWSKAADLFESEGAKVLEVSLP 318
Cdd:PRK07056 228 CCALVDAVLAGEEPVV--------------PAARPLEGLRLAVPTTVVLDGLDATVAAAFERALKRLSAAGAIIEEIAFP 293

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 319 HtsysivcyhvlcTSEVASNMARFdGLQyghrcdinvSTEAmYA------ATRREGFNDVVRGRILSGNffllKENYENY 392
Cdd:PRK07056 294 E------------LAELAEINAKG-GFS---------AAES-YAwhrpllARHRDQYDPRVAARILRGE----PMSAADY 346

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 393 FVKAQKVRRLIANdfVNAFNSGVDVLLTPTTlseAV--PYLEFIKEDnrtrsaqDDIFTQA----------VNMAGLPAV 460
Cdd:PRK07056 347 IDLLAARAAWIAR--AAARLARFDALVMPTV---PIvpPRIADLEAD-------DAAFFRTnalllrnpslINFLDGCAL 414

                        490       500       510
                 ....*....|....*....|....*....|....*....
gi 383873113 461 SIPVALSNQgLPIGLQFIGRAFCDQQLLTVAKWFEKQVQ 499
Cdd:PRK07056 415 SLPCHAPGE-APVGLMLAGAPGRDDRLLAIALAVEAVLR 452
PRK06061 PRK06061
amidase; Provisional
 5-497 5.29e-41

amidase; Provisional


Pssm-ID: 235686 [Multi-domain]  Cd Length: 483  Bit Score: 154.09  E-value: 5.29e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   5 TLQEVSAALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRYKNGQSLgDLDGIPVAVKDNFSTSG 83
Cdd:PRK06061  19 GLTDQAYQLASGAVTSVELVRRSLRRIEASQpTLNAFRVVRAEAALAEAAEADRRRAAGDRL-PLLGVPIAVKDDVDVAG 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  84 IETT--CAsnmlkGYIPP--YNATVVQKLLDQGALLMGKTNLDE-----FAMGSGstdgiFGPVKNPWSyskqyREkrkq 154
Cdd:PRK06061  98 VPTAfgTA-----GEVPPatADSEVVRRLRAAGAVIVGKTNTCElgqwpFTSGPA-----FGHTRNPWS-----RD---- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 155 npHSKNEDSDwlitggssgGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILT 234
Cdd:PRK06061 159 --HTPGGSSG---------GSAAAVAAGLVTAAIGSDGAGSVRIPAAWTHLVGIKPQRGRISTWPLPEAFNGLTVNGPLA 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 235 RCVDDAAIVLGALAGPDPKDsttVHDPinKPFMLPSLA--DVSKLCIG----IPKEYLIPELSSEVRSLWSKAADLFESE 308
Cdd:PRK06061 228 RTVADAALLLDAASGNHPGD---RHRP--PPVTVSDAVgrAPGPLRIAlstrFPFTGFPAKLHPEIRAAVRRVAEQLALL 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 309 GAKVLEVSLPHTSYSIVCYHVLCTSEVASNMARF-DGLQYGHRCDINVSTeamyaatrregfndvvrGRILSGNFFLLKE 387
Cdd:PRK06061 303 GHTVVPADPDYGLRLGLNFLPRSTAGLRDWAERLgDPVLLDPRTVSNARM-----------------GRLLSQAILRLAR 365

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 388 NYEnyfVKAQkvRRLIAndfvnAFNSgVDVLLTPTTlseAVPYLEFIKEDNRTRSAQDDIFTQAV------NMAGLPAVS 461
Cdd:PRK06061 366 AAE---AAAQ--RRVGS-----IFDI-VDVVLAPTT---AQPPPRVGAFDRLGGWATDRAMIAACpytwpwNVLGWPSIN 431

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|...
gi 383873113 462 IPVALSNQGLPIGLQFIGRAFCDQQLLTVA-------KWFEKQ 497
Cdd:PRK06061 432 VPAGFTSDGLPIGAQLMGPANSEPLLISLAaqleavsGWAERQ 474
PRK05962 PRK05962
amidase; Validated
 39-499 1.50e-37

amidase; Validated


Pssm-ID: 168315 [Multi-domain]  Cd Length: 424  Bit Score: 143.38  E-value: 1.50e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  39 AYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNFSTSGiETTCASNMLKGYIPP--YNATVVQKLLDQGALLM 116
Cdd:PRK05962  17 VFSKLYAERARAEADAADARRRAGRSLGPLDGRIVSIKDLFDVAG-EPTLAGSVIRRDAPPagADALIVQRLRNAGAVII 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 117 GKTNLDEFAmgsgstdgiFGPVKnpwsyskqyrekrkQNPH---SKNEDSDWLITGGSSGGSAAAVSAFTCYAALGSDTG 193
Cdd:PRK05962  96 GKTHMTEFA---------FTPVG--------------LNPHygePGNAIDPARIPGGSSSGAAVSVAEGTSEIAIGSDTG 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 194 GSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAGPDPkdsttvhdpinKPFMLPSLAD 273
Cdd:PRK05962 153 GSVRIPAALNGLVGFKPTARRIPLEGAFPLSPSLDSIGPLARTVADCAAADAVMAGEKP-----------IPLEVLPVAG 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 274 vskLCIGIPKEYLIPELSSEVRSLWSKAADLFESEGAKVLEVslphtsysivcyhvlctsEVASNMARFD-GLQYGHRCD 352
Cdd:PRK05962 222 ---LRIGLPKGYLLADMEPDVAAAFEASLAALEKAGARIADL------------------AIDDLIARLAeATRIGSIAG 280

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 353 INVS-TEAMYAATRREGFNDVVRGRILSGnfflLKENYENYFVKAQKVRRLIANdfVNAFNSGVDVLLTPTTLSEAVPyL 431
Cdd:PRK05962 281 IEAShIHADWLADLDANVDIRVKRPLSRR----IKVPLEAYHRLMRTRAALARA--MDERLAGFDMFALPATPIVAPT-I 353

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 383873113 432 EFIKEDNRTRSAQDDIF---TQAVNMAGLPAVSIPvaLSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQ 499
Cdd:PRK05962 354 ASVSEDEEEYDRVENLLlrnTQVANQFDLCSITLP--MPGMALPAGLMLTARNGSDRRLLAAAASVEKLLE 422
PRK07486 PRK07486
amidase; Provisional
 8-501 6.41e-36

amidase; Provisional


Pssm-ID: 236028 [Multi-domain]  Cd Length: 484  Bit Score: 139.76  E-value: 6.41e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   8 EVSAALKQGQITPTELCQKCLSLIKK-TKFLNAYIT-VSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNFSTSGIE 85
Cdd:PRK07486  16 ALSRAIRRRQVSCVEVMRAYLAHIERvNPAVNAIVAlRDRDALLAEAAEKDAALARGEYRGWLHGMPQAPKDLAPTKGIR 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  86 TTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWSYSKqyrekrkqnphSKNEDSDw 165
Cdd:PRK07486  96 TTLGSPIFADQVPQEDAIVVERMRAAGAIFIGKTNTPEFGLGSHTYNPVYGATRNPYDPSR-----------SAGGSSG- 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 166 litggssggsaaavsafTCYAAL---------GSDTGGSTRNPAAHCGLVGFKPSYGLVSrHGLIP--LVNSMDVPGILT 234
Cdd:PRK07486 164 -----------------GAAAALalrmlpvadGSDMMGSLRNPAAFNNVYGFRPSQGRVP-HGPGGdvFVQQLGTEGPMG 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 235 RCVDDAAIVLGALAGPDPKDSTTV-HDPinKPFMLPSLADVSKLCIG--------IPKEylipelsSEVRSLWSKAADLF 305
Cdd:PRK07486 226 RTVEDVALLLAVQAGYDPRDPLSLaEDP--ARFAQPLEADLRGKRIAwlgdwggyLPME-------AGVLELCEAALATL 296

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 306 ESEGAKVLEVSLPHTSYSI-VCYHVLCTSEVASNMArfdglqyghrcdinvsteAMYA--ATRR----EGFNDVVRGRIL 378
Cdd:PRK07486 297 RELGCDVEAALPAFPPERLwRAWLTLRHFLVGGSLL------------------ALYRdpARRAllkpEAIWEIEGGLAL 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 379 SGnffllKENYENYFVKA---QKVRRLIANdfvnafnsgVDVLLTPTTlsEAVPYlefikeDNRTR-------SAQDDI- 447
Cdd:PRK07486 359 TA-----AQVYEASVIRSawyQALLRLFER---------YDFLALPTA--QVFPF------DAEWRwpraiagRAMDTYh 416

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 383873113 448 -FTQAV---NMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQFP 501
Cdd:PRK07486 417 rWMEVVvpaTLAGLPAISVPVGFNAAGLPMGMQIIGPPRADLAVLQLAHAYEQATDWV 474
PRK07487 PRK07487
amidase; Provisional
 8-482 3.10e-34

amidase; Provisional


Pssm-ID: 236029 [Multi-domain]  Cd Length: 469  Bit Score: 134.71  E-value: 3.10e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   8 EVSAALKQGQITPTELCQKCLSLIKK-TKFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAVKDNFSTSGIET 86
Cdd:PRK07487  12 ELAAAVRSRDVSAREAAEAALARLDAvNPAINAVVDHRPEEALAQADAVDAARARGDDPGPLAGVPVTVKVNVDQAGFAT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  87 TCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWsyskqyrekrkqNPHsknedsdwl 166
Cdd:PRK07487  92 TNGVRLQKDLIAPADSPVVDNLRKAGAVIIGRTNTPAFSYRWFTDNPLHGRTLNPW------------DPS--------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 167 itggssggsaaavsaFTC----------------YAALGSDTGGSTRNPAAHCGLVGFKPSYGLV-------SRHGLipL 223
Cdd:PRK07487 151 ---------------LTPggssggaaaavaagigAIAHGTDIGGSIRYPAYACGVHGLRPTLGRVpaynassPERPI--G 213

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 224 VNSMDVPGILTRCVDDAAIVLGALAGPDPKDSTTVHDPINKPFMLPSLAdvskLCIGIPKEYLIPELSSEVRSlwskAAD 303
Cdd:PRK07487 214 AQLMSVQGPLARTVADLRLALAAMAAPDPRDPWWVPAPLEGPPRPKRVA----LCVRPDGLDVDPEVEAALRD----AAR 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 304 LFESEGAKVLEVS-LPHTSYSIVCYHVLCTSEVASNMARfDGLQYGhrcdinvsTEAMYAATRreGFNDVVRGRILSGnf 382
Cdd:PRK07487 286 RLEDAGWTVEEVDdTPPLREAAELQERLWLGDGYEALLA-AAEAEG--------DPGALAALR--GQRAKARPLDLAG-- 352

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 383 fllkenyenyFVKAQKVRRLIANDFvNAFNSGVDVLLTPTTLSEAVPYLEFIKEDNRTRSAQDDIFTQ-AVNMAGLPAVS 461
Cdd:PRK07487 353 ----------YMNALARRATLTRQW-QLFFEDYPLLLMPVSAELPFPDDLDRQGAEGFRRVWEAQLPQiALPFMGLPGLS 421

                        490       500
                 ....*....|....*....|.
gi 383873113 462 IPVALSNqGLPIGLQFIGRAF 482
Cdd:PRK07487 422 VPTGLVG-GVPVGVQLVAGRF 441
PRK12470 PRK12470
amidase; Provisional
 8-501 7.78e-32

amidase; Provisional


Pssm-ID: 171524 [Multi-domain]  Cd Length: 462  Bit Score: 127.69  E-value: 7.78e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   8 EVSAALKQGQITPTELCQKCLSLIKK-TKFLNAYITVSEEVALKQAEESEKRYKNGQSLgDLDGIPVAVKDNFSTSGIET 86
Cdd:PRK12470  13 AQARMLADGELTAPMLLEVYLQRIERlDSHLRAYRVVLFDRARAEAEAAQQRLDAGERL-PLLGVPIAIKDDVDVAGEVT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  87 TCASnmlKGYIPPY--NATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWSYSKqyrekrkqNPHSKNEDSD 164
Cdd:PRK12470  92 TYGS---AGHGPAAtsDAEVVRRLRAAGAVIIGKTNVPELMIMPFTESLAFGATRNPWDPNR--------TPGGSSGGSA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 165 WLITGGSSGgsaaavsaftcyAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVL 244
Cdd:PRK12470 161 AAVAAGLAP------------VALGSDGGGSIRIPSTWCGLFGLKPQRDRISLEPHDGAWQGLSVNGPIARSVMDAALLL 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 245 GALagpdpkdsTTVHDPiNKPFMLPSLADVSKLCIGIPKEYLIP---ELSSEVRSLWSKAADLFESEGAKVLEVS--LPH 319
Cdd:PRK12470 229 DAT--------TTVPGP-EGEFVAAAAREPGRLRIALSTRVPTPlpvRCGKQELAAVHQAGALLRDLGHDVVVRDpdYPA 299

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 320 TSYSIVCYHVLctsevasNMARFDGLQYGHRCDINVSTEAMYaatrregfndvvrgRIlsGNFFLLKEnyenyfVKAQKV 399
Cdd:PRK12470 300 ATYANYLPRFF-------RGISDDADAQAHPDRLEARTRAIA--------------RL--GSFFSDRR------MAALRA 350

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 400 RRLIANDFVNAFNSGVDVLLTPTTLSEAVPylefIKEDNRT-------RSAQDDIFTQAVNMAGLPAVSIPVALSNQGLP 472
Cdd:PRK12470 351 AEVVLSARIQSIFDDVDVVVTPGTATGPSR----IGAYQRRgavstllLVVQRVPYFQVWNLTGQPAAVVPWDFDGDGLP 426

                        490       500
                 ....*....|....*....|....*....
gi 383873113 473 IGLQFIGRAFCDQQLLTVAKWFEKQVQFP 501
Cdd:PRK12470 427 MSVQLVGRPYDEATLLALAAQIESARPWA 455
PRK06707 PRK06707
amidase; Provisional
 5-499 2.24e-31

amidase; Provisional


Pssm-ID: 235855 [Multi-domain]  Cd Length: 536  Bit Score: 127.33  E-value: 2.24e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   5 TLQEVSAALKQGQITPTELCQKCLSLIKKTKF----LNAYITVSEEVALKQAEESEKRYKNGQSlgDLDGIPVAVKDNFS 80
Cdd:PRK06707  72 TVDELQKMIDDGKLSYEELTSIYLFRIQEHDQngitLNSVTEINPNAMEEARKLDQERSRNKKS--NLYGIPVVVKDNVQ 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  81 TSG-IETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFA------MGSGSTdGIFGPVKNPWSyskqyreKRK 153
Cdd:PRK06707 150 TAKvMPTSAGTYVLKDWIADQDATIVKQLKEEGAFVLGKANMSEWAnylsftMPSGYS-GKKGQNLNPYG-------PIK 221

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 154 QNPHSKNEDSDWLITGGSSGGsaaavsaftcyaALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGIL 233
Cdd:PRK06707 222 FDTSGSSSGSATVVAADFAPL------------AVGTETTGSIVAPAAQQSVVGLRPSLGMVSRTGIIPLAETLDTAGPM 289

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 234 TRCVDDAAIVLGALAGPDPKDSTT--VHDPINKPFMLPSLADVSK-LCIGIpkeYLIPELSSEVR-SLWSKAADLFESEG 309
Cdd:PRK06707 290 ARTVKDAATLFNAMIGYDEKDVMTekVKDKERIDYTKDLSIDGLKgKKIGL---LFSVDQQDENRkAVAEKIRKDLQDAG 366

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 310 AKVlevslphtsysivcyhvlcTSEVASNMARFDGLQ-------------YGHRCDINV-STEAMYAATRREGFNDVVRG 375
Cdd:PRK06707 367 AIL-------------------TDYIQLNNGGVDNLQtleyefkhnvndyFSQQKNVPVkSLEEIIAFNKKDSKRRIKYG 427

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 376 RIL---SGNFFLLKENYENYFVKAQK-VRRLIANDFVnafNSGVDVLLtpttlseavpyleFIKEDNRTRSAqddiftqa 451
Cdd:PRK06707 428 QTLieaSEKSAITKDEFEKVVQTSQEnAKKELDRYLV---EKGLDALV-------------MINNEEVLLSA-------- 483

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 383873113 452 vnMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQ 499
Cdd:PRK06707 484 --VAGYPELAVPAGYDNNGEPVGAVFVGKQFGEKELFNIGYAYEQQSK 529
PRK07869 PRK07869
amidase; Provisional
 8-504 3.80e-30

amidase; Provisional


Pssm-ID: 181154 [Multi-domain]  Cd Length: 468  Bit Score: 123.17  E-value: 3.80e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   8 EVSAALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEEsekrykNGQSLGDLDGIPVAVKDNFSTSGIET 86
Cdd:PRK07869  19 GLAEAIRAGRVSAAEVVEAAIARAEAVNpALNALAYAAFDRARDRAAR------PGSQGGFFSGVPTFIKDNVDVAGLPT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  87 TCASNMlkgyIPPYNAT----VVQKLLDQGALLMGKTNLDEFAMgSGSTDGI-FGPVKNPWsyskqyrekrkqnphskne 161
Cdd:PRK07869  93 MHGSDA----WTPRPAKadsdFARQFLATGLISLGKTQLPEFGF-SASTEHPrLGPVRNPW------------------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 162 DSDwlitggssggsaaavsaFTC------YAAL----------GSDTGGSTRNPAAHCGLVGFKPSYGlvsRHGLIPLVN 225
Cdd:PRK07869 149 NTD-----------------YSAgassggSAALvaagvvpiahANDGGGSIRIPAACCGLVGLKPSRG---RLPLDPELR 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 226 SMDV----PGILTRCVDDAAIVLGALAG--PDPKdsttvhdpinkpfmLPSLADVSK-----LCIGIPKEYLI-PELSSE 293
Cdd:PRK07869 209 RLPVnivaNGVLTRTVRDTAAFYREAERyyRNPK--------------LPPIGDVTGpgkqrLRIAVVTDSVTgREADPE 274

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 294 VRSLWSKAADLFESEGAKVLEVSLPHTSySIVCYHVLCTSEVASNMARFDGLQYG---HRCDINVSTEAMYAATRRegfn 370
Cdd:PRK07869 275 VREAVLATARLLEELGHRVEPVDLPVPA-SFVDDFLLYWGFLAFALVRGGRRTFGpsfDRTRLDNLTLGLARHARR---- 349

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 371 dvvrgRILSGNFFLLkenyenyfvkaqKVRRLIAnDFVNAFNSgVDVLLTPtTLSEAVPYLEFIKEDNRTRSAQDDI--- 447
Cdd:PRK07869 350 -----NLHRLPLAIA------------RLRRLRR-VYARFFGT-YDVVLTP-TLAHTTPEIGYLDPTQDFDTVLDRLisy 409

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 383873113 448 --FTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQFPVIQ 504
Cdd:PRK07869 410 vaFTPLQNATGEPAISLPLGQSSDGLPVGMMFSADVGDEATLLELAYELEEAQPWPRIQ 468
PRK08310 PRK08310
amidase; Provisional
 61-492 5.61e-29

amidase; Provisional


Pssm-ID: 181375 [Multi-domain]  Cd Length: 395  Bit Score: 118.55  E-value: 5.61e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  61 NGQSLGDLDGIPVAVKDNFSTSGIETTCASNMLKGYIPPYNAT--VVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFG-P 137
Cdd:PRK08310  19 PHAASGPLAGLRFAVKDVFDVAGYVTGCGNPDWLAESPVATRTapAVEKLLAAGARFVGKTQTDELAFSLNGQNAHYGtP 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 138 VknpwsyskqyrekrkqNPHSKNEdsdwlITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSR 217
Cdd:PRK08310  99 V----------------NPAAPDR-----VPGGSSSGSAAAVAGGLADFALGTDTGGSVRAPASFCGLYGLRPTHGRISL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 218 HGLIPLVNSMDVPGILTRCVDDAAIVLGALAGPDPKDsttvhDPINKPFMLPSLAdvsklcigipKEYLIPELSSEVRSL 297
Cdd:PRK08310 158 EGVMPLAPSFDTVGWFARDIALLERVGEVLLGDDAQE-----FPLTQRLLIPVDL----------FALLDPAVRAALEAA 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 298 WSKAADLF-ESEGAKVLEVSLPHTSYsivCYHVLCTSEVAsnmarfdgLQYGHRcdINvsteamyaATRREgFNDVVRGR 376
Cdd:PRK08310 223 LARLRPHLgPAKPASVPPLSLDEWYE---AFRVLQAAEAW--------ETHGAW--IS--------SGNPQ-LGPGVADR 280

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 377 ilsgnfFLLKENYENYFVKAQKVRRLIANDFVNAFNSGVDVLLTPTTLSEAvPYLefikedNRTRSAQDDIFTQAVNM-- 454
Cdd:PRK08310 281 ------FAAGAEVTADQVEAARARRAAFARELAALLGPDAVLLLPTVPGAA-PLR------GAPFEALEAYRERALRLlc 347

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 383873113 455 ----AGLPAVSIPVAlSNQGLPIGLQFIGRAFCDQQLLTVAK 492
Cdd:PRK08310 348 iaglAGLPQISLPLA-SVDGAPFGLSLIGPRGSDRSLLALAQ 388
PRK06529 PRK06529
amidase; Provisional
 12-500 6.63e-29

amidase; Provisional


Pssm-ID: 180608 [Multi-domain]  Cd Length: 482  Bit Score: 119.54  E-value: 6.63e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  12 ALKQGQITPTELCQKCLSLIKK-TKFLNAYITVSEEVALkqaEESEKRYKNGQSLGdldGIPVAVKD-NFSTSGIETTCA 89
Cdd:PRK06529  12 AVQQGQVTPLELVTQAIYKAKKlNPTLNAIVSERYEEAL---EEAKQRDFSGKPFA---GVPIFLKDlGQELKGQLSTSG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  90 SNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGPVKNPWSYSKqyrekrkqNPHSKNEDSDWLITG 169
Cdd:PRK06529  86 SRLFKNYQATKTDLYVKRLEDLGFIILGRSNTPEFGFKNISDSSLHGPVNLPFDNSR--------NAGGSSGGAAALVSS 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 170 GSSGGsaaavsaftcyaALGSDTGGSTRNPAAHCGLVGFKPSyglvsrHGLIPLVNS-------MDVPGILTRCVDDAAI 242
Cdd:PRK06529 158 GIVAL------------AAASDGGGSIRIPASFNGLIGLKPS------RGRIPVGPGsyrgwqgASVHFALTKSVRDTRR 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 243 VLGALA-----GPDP-----KDSttVHDPINKPFmlpSLADVSKLCIGIPkeylipeLSSEVRSLWSKAADLFESEGAKV 312
Cdd:PRK06529 220 LLYYLQmyqmeSPFPlatlsKES--LFQSLQRPL---KIAFYQRSPDGSP-------VSLDAAKALKQAVTFLREQGHEV 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 313 LEVS-LP-HTSYSIVCYHVLCTSEVAsnmARFDGLQ--YGH---RCDINVSTEAMYAATRRegfndvvrgrILSGNFFLL 385
Cdd:PRK06529 288 VELEeFPlDMTEVMRSYYIMNSVETA---AMFDDIEdaLGRpmtKDDMETMTWAIYQSGQD----------IPAKRYSQV 354

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 386 KENYENYfvKAQKVRrliandfvnaFNSGVDVLLTPTTLSEAVPYLEFI----------KEDNRTRSAQDDI-------- 447
Cdd:PRK06529 355 LQKWDTY--SATMAS----------FHETYDLLLTFTTNTPAPKHGQLDpdsklmanlaQAEIFSSEEQQNLvetmfeks 422

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 383873113 448 -----FTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQF 500
Cdd:PRK06529 423 laitpYTALANLTGQPAISLPTYETKEGLPMGVQLIAAKGREDLLLGIAEQFEAAGLL 480
PRK11910 PRK11910
amidase; Provisional
 1-247 1.18e-28

amidase; Provisional


Pssm-ID: 183377 [Multi-domain]  Cd Length: 615  Bit Score: 120.13  E-value: 1.18e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   1 MLGRTLQEVSAALKQGQITPTELCQKCLSLIKKTK----FLNAYITVSEEVaLKQAEESEKryKNGQSLGDLDGIPVAVK 76
Cdd:PRK11910 162 IIGADVTKLQQLIATKQLSYKELAGIYLNRIKKYDqnglNLNAITEINPTI-IAEAEQLDK--ENTTNKSALYGMPVLLK 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  77 DNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAmgSGSTDGIfgpvknPWSYSKqyREKRKQNP 156
Cdd:PRK11910 239 DNIGTKELPTSAGTVALKDWVIGKDATIVENLKANGALILGKTNMSEWA--AGMDEDL------PNGYSG--KKGQSKNP 308

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 157 HSKNEDSdwliTGGSSGGSAAAVSAFTCYAaLGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRC 236
Cdd:PRK11910 309 YSSNLDP----SGSSSGSATAATSDFAAIA-IGTETNGSIITPASAQSAVGYKPSQGLVNNKGIIPLSSRFDTPGPLTRT 383

                        250
                 ....*....|.
gi 383873113 237 VDDAAIVLGAL 247
Cdd:PRK11910 384 VNDAYLTTNAL 394
PRK06565 PRK06565
amidase; Validated
 3-495 1.44e-25

amidase; Validated


Pssm-ID: 180626  Cd Length: 566  Bit Score: 110.24  E-value: 1.44e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113   3 GRTLQEVSAALKQGQITPTELCQKCLSLIKK-------TKfLNAyITVSEEVALKQAEESEKRYKNGQSLGDLDGIPVAV 75
Cdd:PRK06565   6 EVSIAELRAALESGRTTAVELVKAYLARIDAydgpatgTA-LNA-VVVRNPDALKEAEASDARRARGETLGPLDGIPYTA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  76 KDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGsGSTDGIFGPVKNPwsYSKQYrekrkqn 155
Cdd:PRK06565  84 KDSYLVKGLTAASGSPAFKDLVAQRDAFTIERLRAAGAICLGKTNMPPMANG-GMQRGVYGRAESP--YNAAY------- 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 156 phsknedsdwlITGGSSGGSAAAVSAFTC--YAA--LGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPG 231
Cdd:PRK06565 154 -----------LTAPFASGSSNGAGTATAasFSAfgLAEETWSSGRGPASNNGLCAYTPSRGVISVRGNWPLTPTMDVVV 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 232 ILTRCVDDAAIVLGALAGPDPkdsTTVHD--------PINK-----PFMLPSLADVSKLC----IGIPKEYLIP------ 288
Cdd:PRK06565 223 PYARTMADLLEVLDVIVADDP---DTRGDlwrlqpwvPIPKasevrPASYLALAAGADALkgkrFGVPRMYINAdpdagt 299

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 289 --------------ELSSEVRSLWSKAADLFESEGAKVLEVSLPhtsysivcyhvlctseVASNmarFDGLQYGHRCDIN 354
Cdd:PRK06565 300 senpgiggptgqriHTRPSVIDLWEAARRALEAAGAEVIEVDFP----------------LVSN---CEGDRPGAPTVFN 360

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 355 ---VSTEAMyaatRRE-------GFNDVVRG---------------RILSGNFFLLKENYENY------FVKA------- 396
Cdd:PRK06565 361 rglVSPEFL----HDElwelsgwAFDDFLRAngdpklnrladvdgpQIFPHDPGTLPNREGDLaagmdeYVNMakrglks 436

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 397 --------------QKVRRLIANDFVNAFnsGVDVLLTPtTLSEAVPYLEFIKEDNRTRSAQDDIFTQAVNMA----GLP 458
Cdd:PRK06565 437 wdqiptlpdglrglEKTRKLDLEDWMDGL--GLDAVLFP-TVADVGPADADVNPASADIAWSNGVWVANGNLAirhlGVP 513

                        570       580       590
                 ....*....|....*....|....*....|....*...
gi 383873113 459 AVSIPV-ALSNQGLPIGLQFIGRAFCDQQLLTVAKWFE 495
Cdd:PRK06565 514 TVTVPMgVMADIGMPVGLTFAGRAYDDNALLRFAAAFE 551
PLN02722 PLN02722
indole-3-acetamide amidohydrolase
 68-298 2.46e-13

indole-3-acetamide amidohydrolase


Pssm-ID: 166363  Cd Length: 422  Bit Score: 71.84  E-value: 2.46e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113  68 LDGIPVAVKDNFSTSGIETtcasnmlkGYIPP----------YNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGIFGP 137
Cdd:PLN02722  27 LHGLTFAVKDIFDVEGYVT--------GFGNPdwarthsaatSTAPAVLAVLRGGATCVGKTIMDEMAYSINGENAHYGT 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 138 VKNPWSYSKQyrekrkqnPHSKNEDSDWLITGGSSGGsaaavsaftcyaALGSDTGGSTRNPAAHCGLVGFKPSYGLVSR 217
Cdd:PLN02722  99 PTNPIAPDRV--------PGGSSSGSAVAVGAKLVDF------------SLGTDTGGSVRVPASYCGIFGFRPSHGAVST 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 383873113 218 HGLIPLVNSMDVPGILTRcvdDAAIV--LGALAGPDPkdsttVHDPInKPFMLPSLADVSKLCiGIPKEYLIPELSSEVR 295
Cdd:PLN02722 159 VGVIPMAQSFDTVGWFAR---DPVILkrVGHVLLQQP-----DVNPI-KPSQIIIAEDCFQLS-SIPHDRLVQVLVKSVE 228


                 ...
gi 383873113 296 SLW 298
Cdd:PLN02722 229 KLF 231
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH