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Conserved domains on  [gi|379642579|ref|NP_001243817|]
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calcium homeostasis modulator protein 4 isoform b [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ca_hom_mod super family cl20714
Calcium homeostasis modulator; This family of proteins control cytosolic calcium concentration. ...
 14-113 1.03e-30

Calcium homeostasis modulator; This family of proteins control cytosolic calcium concentration. They are transmembrane proteins which may be pore-forming ion channels.


The actual alignment was detected with superfamily member pfam14798:

Pssm-ID: 464320  Cd Length: 248  Bit Score: 111.57  E-value: 1.03e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379642579   14 PNVAANLSAPSDVILVRDEIALLHRYQSQMLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAE 93
Cdd:pfam14798 149 AKVPCKKSVLPPVDDEREELLRYLRAQSQILGWLLIAVIILLAFLATCLSRCFSPVSYLQLKYWKNYLEKEQELFEETAK 228

                          90       100
                  ....*....|....*....|
gi 379642579   94 QHSRLLMMHRIKKLFGFIPG 113
Cdd:pfam14798 229 EHARQLAKRNVKCFFESSQP 248
 
Name Accession Description Interval E-value
Ca_hom_mod pfam14798
Calcium homeostasis modulator; This family of proteins control cytosolic calcium concentration. ...
 14-113 1.03e-30

Calcium homeostasis modulator; This family of proteins control cytosolic calcium concentration. They are transmembrane proteins which may be pore-forming ion channels.


Pssm-ID: 464320  Cd Length: 248  Bit Score: 111.57  E-value: 1.03e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379642579   14 PNVAANLSAPSDVILVRDEIALLHRYQSQMLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAE 93
Cdd:pfam14798 149 AKVPCKKSVLPPVDDEREELLRYLRAQSQILGWLLIAVIILLAFLATCLSRCFSPVSYLQLKYWKNYLEKEQELFEETAK 228

                          90       100
                  ....*....|....*....|
gi 379642579   94 QHSRLLMMHRIKKLFGFIPG 113
Cdd:pfam14798 229 EHARQLAKRNVKCFFESSQP 248
 
Name Accession Description Interval E-value
Ca_hom_mod pfam14798
Calcium homeostasis modulator; This family of proteins control cytosolic calcium concentration. ...
 14-113 1.03e-30

Calcium homeostasis modulator; This family of proteins control cytosolic calcium concentration. They are transmembrane proteins which may be pore-forming ion channels.


Pssm-ID: 464320  Cd Length: 248  Bit Score: 111.57  E-value: 1.03e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379642579   14 PNVAANLSAPSDVILVRDEIALLHRYQSQMLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAE 93
Cdd:pfam14798 149 AKVPCKKSVLPPVDDEREELLRYLRAQSQILGWLLIAVIILLAFLATCLSRCFSPVSYLQLKYWKNYLEKEQELFEETAK 228

                          90       100
                  ....*....|....*....|
gi 379642579   94 QHSRLLMMHRIKKLFGFIPG 113
Cdd:pfam14798 229 EHARQLAKRNVKCFFESSQP 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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