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Conserved domains on  [gi|374532817|ref|NP_001243415|]
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golgin subfamily B member 1 isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1906-2778 2.51e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.51e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1906 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1975
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1976 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2048
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2049 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2125
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2126 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2203
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2204 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2281
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2282 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2358
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2359 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2430
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2431 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2510
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2511 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2590
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2591 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2670
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2671 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2746
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 374532817  2747 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2778
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1358-2185 2.76e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.76e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1358 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1437
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1438 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1514
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1515 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1594
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1595 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1674
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1675 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1754
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1755 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1834
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1835 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1908
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1909 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1988
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1989 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2067
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2068 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2147
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 374532817  2148 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 764-1538 7.34e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 7.34e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   764 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 843
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 923
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 1003
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1004 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1082
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1083 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1148
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1149 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1204
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1205 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1255
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1256 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1330
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1331 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1400
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1401 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1468
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 374532817  1469 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1538
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1024 1.78e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   190 QQLQEKEEFISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   270 EESLVGRaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHH 349
Cdd:TIGR02168  283 IEELQKE---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   350 LLEQFEQAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLE 429
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   430 DQLQQKSKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKL 509
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   510 SSQITLLEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLl 569
Cdd:TIGR02168  488 QARLDSLERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK- 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   570 emKEAQEEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEH 649
Cdd:TIGR02168  567 --QNELGRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALEL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   650 QSRTSEEISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEIS 724
Cdd:TIGR02168  638 AKKLRPGYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   725 NLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIH 804
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   805 SLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMD 884
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   885 QLLLEKKRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVS 961
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 374532817   962 SGLKQNYDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1024
Cdd:TIGR02168  932 EGLEVRIDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2459-3192 2.26e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.26e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2459 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2528
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2529 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2602
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2603 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2665
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2666 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2729
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2730 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2801
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2802 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2881
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2882 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2961
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2962 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3041
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  3042 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3121
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 374532817  3122 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3192
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-307 6.79e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 6.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKakltslnkyieemkaqggtvlpte 125
Cdd:COG1196   271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA------------------------ 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  126 pQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQaQ 205
Cdd:COG1196   327 -ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE-E 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  206 LSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ 285
Cdd:COG1196   405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                         250       260
                  ....*....|....*....|..
gi 374532817  286 ELTAAEQRNQILSQQLQQMEAE 307
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGF 506
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1906-2778 2.51e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.51e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1906 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1975
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1976 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2048
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2049 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2125
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2126 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2203
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2204 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2281
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2282 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2358
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2359 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2430
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2431 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2510
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2511 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2590
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2591 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2670
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2671 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2746
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 374532817  2747 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2778
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1358-2185 2.76e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.76e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1358 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1437
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1438 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1514
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1515 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1594
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1595 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1674
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1675 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1754
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1755 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1834
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1835 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1908
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1909 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1988
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1989 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2067
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2068 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2147
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 374532817  2148 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 764-1538 7.34e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 7.34e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   764 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 843
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 923
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 1003
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1004 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1082
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1083 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1148
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1149 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1204
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1205 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1255
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1256 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1330
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1331 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1400
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1401 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1468
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 374532817  1469 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1538
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1024 1.78e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   190 QQLQEKEEFISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   270 EESLVGRaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHH 349
Cdd:TIGR02168  283 IEELQKE---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   350 LLEQFEQAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLE 429
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   430 DQLQQKSKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKL 509
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   510 SSQITLLEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLl 569
Cdd:TIGR02168  488 QARLDSLERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK- 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   570 emKEAQEEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEH 649
Cdd:TIGR02168  567 --QNELGRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALEL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   650 QSRTSEEISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEIS 724
Cdd:TIGR02168  638 AKKLRPGYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   725 NLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIH 804
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   805 SLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMD 884
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   885 QLLLEKKRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVS 961
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 374532817   962 SGLKQNYDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1024
Cdd:TIGR02168  932 EGLEVRIDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1839-2384 1.45e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.45e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1839 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVtkmNLLNQQIQEELSRVTKLKE 1918
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIARLEE 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1919 TAEEEKDDLEeRLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1998
Cdd:COG1196   310 RRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1999 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2078
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2079 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALR 2154
Cdd:COG1196   469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAAL 548

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2155 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2234
Cdd:COG1196   549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2235 EDNC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHS 2307
Cdd:COG1196   629 AARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 374532817 2308 SQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLhEEINM 2384
Cdd:COG1196   709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL-GPVNL 784
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1375-1942 2.32e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.51  E-value: 2.32e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1375 LQQKLESSQLQIAGLeHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1454
Cdd:COG1196   218 LKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1455 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1534
Cdd:COG1196   297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1535 QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEstewQEKHK 1614
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1615 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE------KQLQEAEQEMEEMKEKMRKFAK 1688
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGV 532

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1689 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM----------SEKDSLS 1758
Cdd:COG1196   533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGaigaavdlvaSDLREAD 612

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1759 EEVQDLKHQIEGNVSKQANLEATEKHDNQTN-----VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKD 1833
Cdd:COG1196   613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlreVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1834 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1913
Cdd:COG1196   693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 374532817 1914 TKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1942
Cdd:COG1196   773 EREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2459-3192 2.26e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.26e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2459 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2528
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2529 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2602
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2603 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2665
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2666 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2729
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2730 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2801
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2802 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2881
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2882 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2961
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2962 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3041
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  3042 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3121
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 374532817  3122 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3192
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 764-1125 3.67e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 3.67e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  764 VTELRAQVKQLEmnlAEAERQRRldYesqtahdnllteqihsLSIEAKSKDVKIEVLQNELDDVQLQfseqstlIRSLQS 843
Cdd:COG1196   195 LGELERQLEPLE---RQAEKAER--Y----------------RELKEELKELEAELLLLKLRELEAE-------LEELEA 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 923
Cdd:COG1196   247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRkLQAA 1003
Cdd:COG1196   327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-LEEL 405

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1004 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEysekcvtskcqeieiylkqtisEKEVELQHIRK 1083
Cdd:COG1196   406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA----------------------ELEEEEEALLE 463

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 374532817 1084 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1125
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1500-2093 1.17e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 1.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1500 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD---RSLLENQSLSSSCES 1576
Cdd:PRK03918  163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1577 LKLALEGLTEDKEKL---VKEIESLKSSKIAESTEWQEKHKELQ------KEYEILLQSYENVSNEAERIQHVVEAVRQE 1647
Cdd:PRK03918  243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1648 KQELYGKLRstEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPagdtakecmetllssna 1727
Cdd:PRK03918  323 INGIEERIK--ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG----------------- 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1728 smkEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvSKQANLEATEKHDNQTNV-----TEEGTQSIPGET 1802
Cdd:PRK03918  384 ---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK---ELKKAIEELKKAKGKCPVcgrelTEEHRKELLEEY 457

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1803 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKEriagLEEE-KQKNKEFSQTLENEKNTLLSQ 1881
Cdd:PRK03918  458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE----LEEKlKKYNLEELEKKAEEYEKLKEK 533

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1882 ISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLES 1961
Cdd:PRK03918  534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYN 602

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1962 EMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKI 2040
Cdd:PRK03918  603 EYLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSREL 675

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 374532817 2041 SALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2093
Cdd:PRK03918  676 AGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 640-1235 5.51e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 5.51e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   640 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 719
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   720 AKEISNLNQLIEEFKKNADNNssaftaLSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLL 799
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDK------IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   800 TEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL-------EGAERVRHISSKVEELSQA 872
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   873 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 952
Cdd:pfam15921  477 LRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   953 QVEEDNEVSSGLKQNYDEMSP----------AGQISKEELQ----------HEFDLLKKENEQRKRKLQAAL----INRK 1008
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEkeindrrlelQEFKILKDKKDAKIRELEARVsdleLEKV 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1009 ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY---LKQTISEKEVELQHIRKDL 1085
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTL 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1086 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEisenqaiIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1165
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK-------IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1166 ELEEKILALEkekeqlQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1235
Cdd:pfam15921  789 AGELEVLRSQ------ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPG 852
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1844-2344 8.58e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.70  E-value: 8.58e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1844 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLKETAEEE 1923
Cdd:PRK03918  230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDE 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1924 KDDLEERLMNQLAELNGsIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE------EEKQQLVKEKTKVESEIRKEYLE 1997
Cdd:PRK03918  309 LREIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTPE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1998 KIQGAQKEPGNKShaKELQELLKEKQQEVKQLQKDCIRYQEKISALER------------TVKALEFVQTESQKDLEITK 2065
Cdd:PRK03918  388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIE 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2066 ENLAQAVEHRKKAQAELASFKVLLddtqsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2145
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2146 MQ------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL----QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2215
Cdd:PRK03918  541 IKslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2216 werkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHdkqiweskaqtevqlqqkvcdtlqgenkell 2295
Cdd:PRK03918  621 --------LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY------------------------------- 661

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 374532817 2296 sqlEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2344
Cdd:PRK03918  662 ---EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 48-613 9.41e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 9.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   48 EDVQERLAyaeqlvvELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:COG1196   182 EATEENLE-------RLEDILGELERQL----EPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEE 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:COG1196   251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  208 QTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 287
Cdd:COG1196   331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  288 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKL--SFHNLQEEMHHLLEQFEQAGQAQAELE 365
Cdd:COG1196   411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALleLLAELLEEAALLEAALAELLEELAEAA 490

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  366 SRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQA---------VQSAQTIQQLEDQLQQKS 436
Cdd:COG1196   491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAlaaalqnivVEDDEVAAAAIEYLKAAK 570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  437 KEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELK--AENEKLSSQIT 514
Cdd:COG1196   571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRraVTLAGRLREVT 650

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  515 LLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEAD 594
Cdd:COG1196   651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                         570
                  ....*....|....*....
gi 374532817  595 HEVLDQKEMKQMEGEGIAP 613
Cdd:COG1196   731 EAEREELLEELLEEEELLE 749
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1306-2184 4.95e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 4.95e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1306 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1385
Cdd:pfam02463  161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1386 IagLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1465
Cdd:pfam02463  241 L--LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1466 LCEMKQKpeeigeesrakqqIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1545
Cdd:pfam02463  319 SEKEKKK-------------AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1546 LALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1625
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1626 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1705
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1706 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1785
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1786 NQTNVTEEGTQSIPGETEEQDSLSMstrptcsesVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1865
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRK---------GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1866 EFSQTLENEKNTLLSQISTKDGELKMLQEEVT-KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1944
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQeAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1945 YCQDVTDAQIKNElLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepgnKSHAKELQELLKEKQQ 2024
Cdd:pfam02463  777 AEEREKTEKLKVE-EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK--------EEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2025 EVKQLQKDCIRYQEKISALERTVKALEfvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL 2104
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLL----KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2105 KLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2184
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2643-2946 9.30e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 9.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2643 EEEVHRLSALFSSSQKRIAELEEelvcvQKEAAKKVGEIEDKLKK--------ELKHLHHDAGIMRNETETAEERVAELA 2714
Cdd:COG1196   185 EENLERLEDILGELERQLEPLER-----QAEKAERYRELKEELKEleaellllKLRELEAELEELEAELEELEAELEELE 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2715 RDLVEME-------QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2787
Cdd:COG1196   260 AELAELEaeleelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2788 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR----KS 2863
Cdd:COG1196   340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerleRL 419

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2864 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEEL 2943
Cdd:COG1196   420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499


                  ...
gi 374532817 2944 RQE 2946
Cdd:COG1196   500 EAD 502
PTZ00121 PTZ00121
MAEBL; Provisional
 707-1234 2.73e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.73e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  707 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQ 784
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  785 RRLDYESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 857
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  858 RVRHISSKVEELSQA--LSQKELEITKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 933
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  934 KTLKEqlnlLSRAEEAKKEQVEEDNEVssglKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1013
Cdd:PTZ00121 1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1014 VSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE 1093
Cdd:PTZ00121 1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1094 QFQAlvKQMNQTLQDKTNQIDLLQAEISENQaiiqklitsntdasdgdsvalvketvvisppctgssehwKPELEEKILA 1173
Cdd:PTZ00121 1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 374532817 1174 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1234
Cdd:PTZ00121 1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1952-2708 8.41e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 8.41e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1952 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2031
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2032 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2111
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2112 SNKESVKSQMKQKDEDLERRL------EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2186 dstvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHD 2265
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2266 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK--DQLTDLSNSLEKCKEQKGNL 2343
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2344 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS 2423
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2424 QEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLI 2503
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2504 QEAAAE--NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKL 2581
Cdd:pfam02463  727 VQEAQDkiNEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2582 KESEEANEDLRRSFNALQE-EKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEvhrlsalfsSSQKRI 2660
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEqEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQE---------LLLKEE 877

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 374532817  2661 AELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEE 2708
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE 925
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 35-621 5.18e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 5.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817    35 HQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEM 114
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   115 KAQG--------------------------------GTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHK-LQEKEELIS 161
Cdd:pfam15921  155 EAAKclkedmledsntqieqlrkmmlshegvlqeirSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKiLRELDTEIS 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   162 TLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEK-EEFISTLQAQLS------QTQAEQAAQLSSMQQVVREKDARFETQ 234
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRiEQLISEHEVEITgltekaSSARSQANSIQSQLEIIQEQARNQNSM 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   235 VRLHEDELLQLVTQadVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 314
Cdd:pfam15921  315 YMRQLSDLESTVSQ--LRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   315 VETEREESKILLEK-----MELEVAERKLSFHNLQ-EEMHHLLEQFEQagQAQAELESRYSALEQKHKAeMEEKTSHILS 388
Cdd:pfam15921  393 LSLEKEQNKRLWDRdtgnsITIDHLRRELDDRNMEvQRLEALLKAMKS--ECQGQMERQMAAIQGKNES-LEKVSSLTAQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   389 LQKTGQELQSACDALKDQnsKLLQDKNEQAVQS-AQTIQQLEDQLQQKSKEISQFLNRLPLQ----QHETASQTSFPDVY 463
Cdd:pfam15921  470 LESTKEMLRKVVEELTAK--KMTLESSERTVSDlTASLQEKERAIEATNAEITKLRSRVDLKlqelQHLKNEGDHLRNVQ 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   464 NE---------GTQAVTE---ENIASLQKRVVELENEKGALLLSS-----------IELEELKAENEKLSSQITLLEAQn 520
Cdd:pfam15921  548 TEcealklqmaEKDKVIEilrQQIENMTQLVGQHGRTAGAMQVEKaqlekeindrrLELQEFKILKDKKDAKIRELEAR- 626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   521 rtgEADREVSEISIVDIANKRSSSAEESGQ--DVLENTFSQKHKELSVLLLEM---------KEAQEEIAFLKLQLQGKR 589
Cdd:pfam15921  627 ---VSDLELEKVKLVNAGSERLRAVKDIKQerDQLLNEVKTSRNELNSLSEDYevlkrnfrnKSEEMETTTNKLKMQLKS 703

                          650       660       670
                   ....*....|....*....|....*....|..
gi 374532817   590 AEEADHEVldQKEMKQMEGEGIAPIKMKVFLE 621
Cdd:pfam15921  704 AQSELEQT--RNTLKSMEGSDGHAMKVAMGMQ 733
PRK11281 PRK11281
mechanosensitive channel MscK;
151-513 9.40e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.84  E-value: 9.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  151 HKLQEKEEliSTLQAQLTQAQA--EQPAQSSTEMEEfvmMKQQLQEkeefistLQAQLSQTQAEQAAQLSSMQQVVREkd 228
Cdd:PRK11281   51 QKLLEAED--KLVQQDLEQTLAllDKIDRQKEETEQ---LKQQLAQ-------APAKLRQAQAELEALKDDNDEETRE-- 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  229 aRFETqvrLHEDELLQLVTQadVETEMQQklrvLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEH 308
Cdd:PRK11281  117 -TLST---LSLRQLESRLAQ--TLDQLQN----AQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGG 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  309 NTLRNTVETERE------ESKILLEKMELEVAERKLSFHNLQeemHHLLEqfEQAGQAQAELESRYSALEQKHKAEMEek 382
Cdd:PRK11281  187 KALRPSQRVLLQaeqallNAQNDLQRKSLEGNTQLQDLLQKQ---RDYLT--ARIQRLEHQLQLLQEAINSKRLTLSE-- 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  383 tshilslqKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQT-IQQLE--DQLQQKSKEISQFLNRlpLQQhetasqtsf 459
Cdd:PRK11281  260 --------KTVQEAQSQDEAARIQANPLVAQELEINLQLSQRlLKATEklNTLTQQNLRVKNWLDR--LTQ--------- 320

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 374532817  460 pdvynegTQAVTEENIASLQkrvvelenekGALLLSSIELEELKA-----ENEKLSSQI 513
Cdd:PRK11281  321 -------SERNIKEQISVLK----------GSLLLSRILYQQQQAlpsadLIEGLADRI 362
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1829-2067 5.67e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 5.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1829 AVSKDFSSHDEINNYLQQIDQLKERIAgleeEKQKNKEFSQTLENEKNTLLSQISTKDGELkmlqeEVTKMNLLNQQIQE 1908
Cdd:NF012221 1536 ATSESSQQADAVSKHAKQDDAAQNALA----DKERAEADRQRLEQEKQQQLAAISGSQSQL-----ESTDQNALETNGQA 1606

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1909 ELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGN-YCQDVTDAQIKNelLESEMKNLKKCVSE-LEEEKQQLVKEK 1984
Cdd:NF012221 1607 QRDAILEESRAVTKELTTLAQGLdaLDSQATYAGESGDqWRNPFAGGLLDR--VQEQLDDAKKISGKqLADAKQRHVDNQ 1684

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1985 TKVESEIRKEYLEKIQGAQKEPG-------NKSHAKELQELLKEKQQEVKQLQKDC-IRYQEKISALERTVKALEFVQTE 2056
Cdd:NF012221 1685 QKVKDAVAKSEAGVAQGEQNQANaeqdiddAKADAEKRKDDALAKQNEAQQAESDAnAAANDAQSRGEQDASAAENKANQ 1764

                         250
                  ....*....|.
gi 374532817 2057 SQKDLEITKEN 2067
Cdd:NF012221 1765 AQADAKGAKQD 1775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-307 6.79e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 6.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKakltslnkyieemkaqggtvlpte 125
Cdd:COG1196   271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA------------------------ 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  126 pQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQaQ 205
Cdd:COG1196   327 -ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE-E 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  206 LSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ 285
Cdd:COG1196   405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                         250       260
                  ....*....|....*....|..
gi 374532817  286 ELTAAEQRNQILSQQLQQMEAE 307
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGF 506
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2042-2211 7.07e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 41.52  E-value: 7.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2042 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2117
Cdd:NF033928   88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2118 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2174
Cdd:NF033928  165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 374532817 2175 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2211
Cdd:NF033928  245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1906-2778 2.51e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.51e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1906 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1975
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1976 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2048
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2049 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2125
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2126 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2203
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2204 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2281
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2282 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2358
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2359 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2430
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2431 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2510
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2511 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2590
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2591 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2670
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2671 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2746
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 374532817  2747 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2778
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1358-2185 2.76e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.76e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1358 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1437
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1438 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1514
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1515 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1594
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1595 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1674
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1675 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1754
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1755 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1834
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1835 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1908
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1909 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1988
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1989 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2067
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2068 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2147
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 374532817  2148 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1307-2092 4.86e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.05  E-value: 4.86e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1307 TSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGL-EIESLKTVSHEAEVHAESLQQKLESSQLQ 1385
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1386 iaglehLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1462
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1463 QVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARGTIERLTKSLADVESQ 1531
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1532 VSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGL--------------------------- 1584
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtvaqlgsvgeryataievaagnrln 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1585 ---TEDKEKLVKEIESLKSSKIAEST-----EWQEKHKELQKEYE-----ILL------QSYENVSNEAERIQHVVEAVr 1645
Cdd:TIGR02169  551 nvvVEDDAVAKEAIELLKRRKAGRATflplnKMRDERRDLSILSEdgvigFAVdlvefdPKYEPAFKYVFGDTLVVEDI- 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1646 QEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMrkFAKSKQQKILELEEENDRLRAEVhpagdtakecmetllss 1725
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGIL--FSRSEPAELQRLRERLEGLKREL----------------- 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1726 nASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEatekhdnqtnvteegtqsipgetEEQ 1805
Cdd:TIGR02169  691 -SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE-----------------------EDL 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1806 DSLSmstrptcsesvpsaksanpavskdfsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTllSQISTK 1885
Cdd:TIGR02169  747 SSLE----------------------------QEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEI 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1886 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKN 1965
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1966 LKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR---------- 2035
Cdd:TIGR02169  873 LEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeels 952

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2036 ---YQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDT 2092
Cdd:TIGR02169  953 ledVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 764-1538 7.34e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 7.34e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   764 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 843
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 923
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 1003
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1004 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1082
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1083 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1148
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1149 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1204
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1205 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1255
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1256 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1330
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1331 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1400
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1401 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1468
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 374532817  1469 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1538
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 768-1651 2.13e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 2.13e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   768 RAQVKQLEMNLAEAERQ-RRLDYESQTAHDNL-LTEQIHSLSIEAKSKDvkIEVLQNELDDVQLQFSEQSTLIRSLQSQL 845
Cdd:TIGR02168  185 RENLDRLEDILNELERQlKSLERQAEKAERYKeLKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   846 QNKESEvlegaervrhisskveelsqaLSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLNEE 925
Cdd:TIGR02168  263 QELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   926 KFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAgqisKEELQHEFDLLKKENEQRKRKLQAALI 1005
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1006 NRKELLQRVSRLEEELANLKDESKKEiplsETERGEVEEDKENKEYSEkcvtskcqeieiyLKQTISEKEVELQHIRKDL 1085
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQEEL 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1086 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASdgdSVALVKETVVISPPCTGSSEHWKP 1165
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK---ALLKNQSGLSGILGVLSELISVDE 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1166 ELEEKILALekekeqLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIGDQL 1238
Cdd:TIGR02168  534 GYEAAIEAA------LGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAKDL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1239 RQLQIQVRESIDGKLpstdqqescsSTPGLEEPLFKATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQIKA 1314
Cdd:TIGR02168  608 VKFDPKLRKALSYLL----------GGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1315 QLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE 1394
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1395 lqpkldELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALhtqlemqakehDERIKQLQVELCEMKqkpE 1474
Cdd:TIGR02168  758 ------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL-----------REALDELRAELTLLN---E 817

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1475 EIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERD 1554
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE 897

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1555 KLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEstewqekhkELQKEYEILLQSYENVSNEA 1634
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIEDDE 967

                          890
                   ....*....|....*..
gi 374532817  1635 ERIQHVVEAVRQEKQEL 1651
Cdd:TIGR02168  968 EEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2021-2789 2.22e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 2.22e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2021 EKQQEVKQLQKDC----IRYQEKISALERTVKALEFVQTESQkdLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEA 2096
Cdd:TIGR02168  199 ERQLKSLERQAEKaeryKELKAELRELELALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2097 ARVLADNLKLKKELQSnkesvksqMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDK 2176
Cdd:TIGR02168  277 SELEEEIEELQKELYA--------LANEISRLEQQKQILRER----LANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2177 EVQQLQENLDStvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEirlkedncSVLKDQLRQMSIHMEELK 2256
Cdd:TIGR02168  345 KLEELKEELES---LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2257 INISRLEHDKQIWESKAQ-TEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEK 2335
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2336 CKEQKGNLEGIIRQQEADIQN-SKFSY------EQLETDLQASRELTSRLHEEINM-------KEQKIISLLSgKEEAIQ 2401
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNqSGLSGilgvlsELISVDEGYEAAIEAALGGRLQAvvvenlnAAKKAIAFLK-QNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2402 VAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETL--KTIKKENIQQKAQL--------------- 2464
Cdd:TIGR02168  573 VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNALELakklrpgyrivtldg 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2465 -------------DSFVKSMSSLQNDRDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSEN 2531
Cdd:TIGR02168  653 dlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEK----IAELEKALAELRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2532 AKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQN-------------KELENKYAKLEEKLKESEEANEDLRRSFNAL 2598
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2599 QEEKQDLSKEIESLKVSISQLTRQVTALQEEgtLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqkeaaKKV 2678
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERR--LEDLEEQIEELSEDIESLAAEIEELEELIEELESEL--------EAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2679 GEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFgrsmssLQNSRDHANEE 2758
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL------QERLSEEYSLT 952

                          810       820       830
                   ....*....|....*....|....*....|..
gi 374532817  2759 LDELKRKYDASLKELAQLKEQ-GLLNRERDAL 2789
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRlKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1311-2192 7.87e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 7.87e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1311 QIKAQLKEIE-----AEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1385
Cdd:TIGR02168  217 ELKAELRELElallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1386 IAGLEH-LRELQPKLDELQKLISKKEEdvsylsgQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQv 1464
Cdd:TIGR02168  297 ISRLEQqKQILRERLANLERQLEELEA-------QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE- 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1465 elcEMKQKPEEigeesrakqqiqrkLQAALISRKEALKEnksLQEELSLARGTIERLTKSLADVESqvsaqnkekdtvlg 1544
Cdd:TIGR02168  369 ---ELESRLEE--------------LEEQLETLRSKVAQ---LELQIASLNNEIERLEARLERLED-------------- 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1545 RLALLQEERDKLITEMDRSllENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQkEYEILL 1624
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1625 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1704
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1705 RAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLkhqiegnvsKQANLEATEKH 1784
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDL---------DNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1785 DNQTNVTEEGTQSIPGETeeqdslsmstrptcsesvpSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKN 1864
Cdd:TIGR02168  643 PGYRIVTLDGDLVRPGGV-------------------ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1865 KEFSQTLENEKNTLLSQISTKDGELKMLQEEV----TKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQLAELNG 1940
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLarleAEVEQLEERIAQLSKELTELEAEIEELEERLEE-AEEELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1941 SIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLK 2020
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2021 EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT-------KENLAQAVEHRKKAQAELASFKVLLDDTQ 2093
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskrselRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2094 SEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ---------AEEKHLKEKKN-MQEKLDALRREKVHLEET 2163
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaaiEEYEELKERYDfLTAQKEDLTEAKETLEEA 1022

                          890       900       910
                   ....*....|....*....|....*....|
gi 374532817  2164 IGEI-QVTLNKKDKEVQQLQENLDSTVTQL 2192
Cdd:TIGR02168 1023 IEEIdREARERFKDTFDQVNENFQRVFPKL 1052
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2124-2960 8.42e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 8.42e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2124 KDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLN------KKDKEVQQLQENLDSTvtQLAAF 2195
Cdd:TIGR02168  153 KPEERRAIFEEAAgiSKYKERRKETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELREL--ELALL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2196 TKSMSSLQDDRDRVIDEAKKWERKFSDA---IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK 2272
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELtaeLQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2273 AQTEVQLQQKVCDTLQgenkELLSQLEETrhlyhssQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2352
Cdd:TIGR02168  311 LANLERQLEELEAQLE----ELESKLDEL-------AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2353 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQ----VAIAELRQQHDKEIKELENLLSQEeee 2428
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKkleeAELKELQAELEELEEELEELQEEL--- 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2429 nivleeenkkavdktNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsiilekdqlIQEAAA 2508
Cdd:TIGR02168  457 ---------------ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG------------FSEGVK 509

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2509 ENNKLKEEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEA 2587
Cdd:TIGR02168  510 ALLKNQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGN 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2588 NEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQV-------TALQ-----------------------------EEGT 2631
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddldNALElakklrpgyrivtldgdlvrpggvitggsAKTN 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2632 LGLYHAQLKVKE--EEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETETAEER 2709
Cdd:TIGR02168  670 SSILERRREIEEleEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL-SRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2710 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDAL 2789
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2790 LSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqr 2869
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELS-------- 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2870 saaqpstspAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELhpLKAQLQEYQDKTKAFQIMQEELRQENLS 2949
Cdd:TIGR02168  901 ---------EELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEE 969

                          890
                   ....*....|.
gi 374532817  2950 WQHELHQLRME 2960
Cdd:TIGR02168  970 ARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1309-2178 2.73e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 83.19  E-value: 2.73e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1309 VAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQgLEIESLKTVSHEAEVHA-----ESLQQKLESSQ 1383
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEGYEllkekEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1384 LQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEK-EAALTKIQTEIIEQEDLIKALHTQL---EMQAKEHDER 1458
Cdd:TIGR02169  244 RQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIaekERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1459 IKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEalkenkslqeELSLARGTIERLTKSLADVESQVSAQNKE 1538
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE----------ELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1539 KDTvlgrlalLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDkeklVKEIESLKSSKIAESTEWQEKHKELQK 1618
Cdd:TIGR02169  394 LEK-------LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK----INELEEEKEDKALEIKKQEWKLEQLAA 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1619 EYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELE 1698
Cdd:TIGR02169  463 DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1699 -EENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVqDLKHQIEgNVSKQA- 1776
Cdd:TIGR02169  543 vAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLV-EFDPKYE-PAFKYVf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1777 -------NLEATEKH-DNQTNVTEEGtqsipgeteeqDSLSMSTRPTCSESVPSAKSANPAvskdfsshdeinNYLQQID 1848
Cdd:TIGR02169  621 gdtlvveDIEAARRLmGKYRMVTLEG-----------ELFEKSGAMTGGSRAPRGGILFSR------------SEPAELQ 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1849 QLKERIAGLEEEKQKNKEFSQTLENEKNTLLS-------QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1921
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIENRLDELSQelsdasrKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1922 EEKDDLEERlmnqLAELNGSIGNYCQDVTDaqIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG 2001
Cdd:TIGR02169  758 SELKELEAR----IEELEEDLHKLEEALND--LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2002 AQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAE 2081
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2082 LASFKVLLDDTQsEAARVLADNLK----LKKELQSNKESVKS--QMKQKDEDLERRLEQAE----------EKHLKEKKN 2145
Cdd:TIGR02169  912 IEKKRKRLSELK-AKLEALEEELSeiedPKGEDEEIPEEELSleDVQAELQRVEEEIRALEpvnmlaiqeyEEVLKRLDE 990

                          890       900       910
                   ....*....|....*....|....*....|...
gi 374532817  2146 MQEKLDALRREKVHLEETIGEiqvtLNKKDKEV 2178
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEE----YEKKKREV 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1837-2534 4.44e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.44e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1837 HDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKL 1916
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1917 KETAEEEKDDLEERLMNQLAELNGS---IGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1993
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1994 EYLE-KIQGAQKEPGNKSHAKELQELLK-EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTEsqkdLEITKENLAQA 2071
Cdd:TIGR02168  398 LNNEiERLEARLERLEDRRERLQQEIEElLKKLEEAELKELQAELEELEEELEELQEELERLEEA----LEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2072 VEHRKKAQAELASFKVLLDDTQSEAARVL-----ADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK----E 2142
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEgfsegVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavvvE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2143 KKNMQEK-LDALRREKVH----LEETI---GEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSL------QDDRDR 2208
Cdd:TIGR02168  554 NLNAAKKaIAFLKQNELGrvtfLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2209 VIDEAKKW-----------------------ERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLE-- 2263
Cdd:TIGR02168  634 ALELAKKLrpgyrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEee 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2264 ---------------HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTD 2328
Cdd:TIGR02168  714 leqlrkeleelsrqiSALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2329 LSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLlsgkeeaiQVAIAELR 2408
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL--------AAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2409 QQHDKEIKELENLLSQEEEENIVLEEENKKAvdktNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2488
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 374532817  2489 EERhlsiILEKDQLIQEAAAEN-NKLKEEIRGLRSHMDDLNSENAKL 2534
Cdd:TIGR02168  942 QER----LSEEYSLTLEEAEALeNKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1024 1.78e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   190 QQLQEKEEFISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   270 EESLVGRaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHH 349
Cdd:TIGR02168  283 IEELQKE---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   350 LLEQFEQAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLE 429
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   430 DQLQQKSKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKL 509
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   510 SSQITLLEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLl 569
Cdd:TIGR02168  488 QARLDSLERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK- 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   570 emKEAQEEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEH 649
Cdd:TIGR02168  567 --QNELGRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALEL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   650 QSRTSEEISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEIS 724
Cdd:TIGR02168  638 AKKLRPGYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   725 NLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIH 804
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   805 SLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMD 884
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   885 QLLLEKKRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVS 961
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 374532817   962 SGLKQNYDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1024
Cdd:TIGR02168  932 EGLEVRIDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1839-2384 1.45e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.45e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1839 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVtkmNLLNQQIQEELSRVTKLKE 1918
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIARLEE 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1919 TAEEEKDDLEeRLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1998
Cdd:COG1196   310 RRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1999 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2078
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2079 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALR 2154
Cdd:COG1196   469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAAL 548

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2155 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2234
Cdd:COG1196   549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2235 EDNC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHS 2307
Cdd:COG1196   629 AARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 374532817 2308 SQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLhEEINM 2384
Cdd:COG1196   709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL-GPVNL 784
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1843-2626 1.46e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.40  E-value: 1.46e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1843 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEE 1922
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1923 EKDDLEerlmNQLAELNGSIgnycqdvtdaqiknELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEylekiqgA 2002
Cdd:TIGR02168  310 RLANLE----RQLEELEAQL--------------EELESKLDELAEELAELEEKLEELKEELESLEAELEEL-------E 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2003 QKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqTESQKDLEITKENLAQAVEHRKKA-QAE 2081
Cdd:TIGR02168  365 AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DRRERLQQEIEELLKKLEEAELKElQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2082 LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKS------QMKQKDEDLERRLEQAEEKHLKEKKNMQEKLD---- 2151
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAaerelaQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgi 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2152 -ALRREKVH--------LEETIGE-----IQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRD---------- 2207
Cdd:TIGR02168  522 lGVLSELISvdegyeaaIEAALGGrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDReilkniegfl 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2208 RVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLkDQLRQM------------------SIHMEELKINISRLEHDKQIW 2269
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNAL-ELAKKLrpgyrivtldgdlvrpggVITGGSAKTNSSILERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2270 ESKAQtevqlqqkvCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ 2349
Cdd:TIGR02168  681 ELEEK---------IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2350 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2429
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI--------EQLKEELKALREALDELRAELTLLNEEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2430 IVLEEENKKAVDKTNQLMETLKTIKKENIQQK---AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL---I 2503
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIEslaAEIEELEELIEELESELEALLNERASLEEALALLRSELEELseeL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2504 QEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLN--QVITIKDSQQKQLLEVQLQQN-----KELENKYAK 2576
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSeeYSLTLEEAEALENKIEDDEEEarrrlKRLENKIKE 983

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 374532817  2577 LEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2626
Cdd:TIGR02168  984 LGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1375-1942 2.32e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.51  E-value: 2.32e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1375 LQQKLESSQLQIAGLeHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1454
Cdd:COG1196   218 LKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1455 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1534
Cdd:COG1196   297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1535 QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEstewQEKHK 1614
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1615 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE------KQLQEAEQEMEEMKEKMRKFAK 1688
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGV 532

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1689 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM----------SEKDSLS 1758
Cdd:COG1196   533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGaigaavdlvaSDLREAD 612

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1759 EEVQDLKHQIEGNVSKQANLEATEKHDNQTN-----VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKD 1833
Cdd:COG1196   613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlreVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1834 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1913
Cdd:COG1196   693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 374532817 1914 TKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1942
Cdd:COG1196   773 EREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1311-1600 7.65e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 7.65e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1311 QIKAQLKEIEAEKVELELKvssttsELTKKSEEvfqLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL- 1389
Cdd:COG1196   217 ELKEELKELEAELLLLKLR------ELEAELEE---LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAq 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1390 EHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1469
Cdd:COG1196   288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1470 KQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALL 1549
Cdd:COG1196   368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 374532817 1550 QEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS 1600
Cdd:COG1196   448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 799-1769 8.42e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 8.42e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   799 LTEQIHSLSIEAKsKDVKIEVLQNELDDVQLQFSEQStlIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKEL 878
Cdd:TIGR02168  198 LERQLKSLERQAE-KAERYKELKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   879 EITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDN 958
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   959 EVSSGLKQNYDEMSPAgqisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEiplsETE 1038
Cdd:TIGR02168  351 EELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL----QQE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1039 RGEVEEDKENKEYSEkcvtskcqeieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQA 1118
Cdd:TIGR02168  423 IEELLKKLEEAELKE-------------LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1119 EISENQAIIQKLITSNTDASdgdSVALVKETVVISPPCTGSSEHWKPELEEKILALekekeqLQKKLQEALTSRKAILKK 1198
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVK---ALLKNQSGLSGILGVLSELISVDEGYEAAIEAA------LGGRLQAVVVENLNAAKK 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1199 AQEkerhlreelkqqkddynrlqeqFDEQSKenenigdqLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLfkateq 1278
Cdd:TIGR02168  561 AIA----------------------FLKQNE--------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA------ 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1279 hhtqpvleSNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTseltkkseevfqlqEQINKQGLei 1358
Cdd:TIGR02168  605 --------KDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDG--------------DLVRPGGV-- 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1359 eslkTVSHEAEVHAESLQQKLEssqlqiaglehLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQE 1438
Cdd:TIGR02168  661 ----ITGGSAKTNSSILERRRE-----------IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1439 DLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqaalisrKEALKENKSLQEELSLARGTI 1518
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-------AEAEAEIEELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1519 ERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESL 1598
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1599 ksskiaestewQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEkqlqeaeqemee 1678
Cdd:TIGR02168  879 -----------LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE------------ 935

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1679 mkekmrkfakskqqkiLELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKM--------------EYETLS 1744
Cdd:TIGR02168  936 ----------------VRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaaieEYEELK 999

                          970       980
                   ....*....|....*....|....*
gi 374532817  1745 KKFQSLMSEKDSLSEEVQDLKHQIE 1769
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTEAKETLEEAIE 1024
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2459-3192 2.26e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.26e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2459 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2528
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2529 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2602
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2603 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2665
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2666 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2729
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2730 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2801
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2802 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2881
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2882 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2961
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2962 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3041
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  3042 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3121
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 374532817  3122 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3192
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1970-2794 2.47e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.56  E-value: 2.47e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1970 VSELEEEKQQLVKEKTKVESEIRKEYL---EKIQGAQKEPGNKSHAKELQELLKEKQQ-EVKQLQKDCIRYQEKISALER 2045
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2046 TVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAsfkvllDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKD 2125
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK------DLGEEEQLRVKEKIGELEAEIASLERSIAEK-EREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2126 EDLERRLEQAEE---KHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK-------KDKEVQQLQENLDSTVTQLAAF 2195
Cdd:TIGR02169  318 EDAEERLAKLEAeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDlraeleeVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2196 TKSMSSLQDDRDRVIDEAKKWERKFSDAiqskEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQT 2275
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADL----NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2276 EVQLQQKVCDTLQGENKElLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQ---------KGNLEGI 2346
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRE-LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaaGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2347 IRQQEADIQN----------SKFSYEQLeTDLQASRELTSRLHE-----------EINMKEQKII-----------SLLS 2394
Cdd:TIGR02169  553 VVEDDAVAKEaiellkrrkaGRATFLPL-NKMRDERRDLSILSEdgvigfavdlvEFDPKYEPAFkyvfgdtlvveDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2395 GKEEAIQVAIAELrqqhDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEniqqkaqLDSFVKSMSSL 2474
Cdd:TIGR02169  632 ARRLMGKYRMVTL----EGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRE-------LSSLQSELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2475 QNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE---EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITI 2551
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEleeDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2552 KDSQQKQLLEVQLQqnkELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-- 2629
Cdd:TIGR02169  781 LNDLEARLSHSRIP---EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEie 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2630 ---GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqKEAAKKVGEIEDKLKKELKHLhhdaGIMRNETETA 2706
Cdd:TIGR02169  858 nlnGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL----RELERKIEELEAQIEKKRKRL----SELKAKLEAL 929

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2707 EERVAELARDLVEMEQKLLMVTKENKgLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEqgllnrER 2786
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEE------ER 1002


                   ....*...
gi 374532817  2787 DALLSETA 2794
Cdd:TIGR02169 1003 KAILERIE 1010
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1575-2383 9.39e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 9.39e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1575 ESLKLALegLTEDKEKLVKEIESLKSSKIAESTEW---QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQEL 1651
Cdd:TIGR02168  223 RELELAL--LVLRLEELREELEELQEELKEAEEELeelTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1652 YGKLRSTEANKKETEKQLQEAEQEMEEMkekmrkfakskQQKILELEEENDRLRAEVhpagDTAKECMETLLSSNASMKE 1731
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQLEEL-----------ESKLDELAEELAELEEKL----EELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1732 ELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEAtEKHDNQTNVTEEGTQSIPGETEEQDSLSMS 1811
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED-RRERLQQEIEELLKKLEEAELKELQAELEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1812 TRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQ----QIDQLKERIAGLEEEKQKNKEFSQTLENEKN----------T 1877
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDaaerELAQLQARLDSLERLQENLEGFSEGVKALLKnqsglsgilgV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1878 LLSQISTKDG---------ELKMLQEEVTKMNLLNQQI----QEELSRVTKLKETAEEEkDDLEERLMNQLAELNGSIGn 1944
Cdd:TIGR02168  525 LSELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIaflkQNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1945 YCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHA---------KEL 2015
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2016 QELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvlLDDTQSE 2095
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2096 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2175
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2176 KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWerkfSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2255
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2256 KINISRL-EHDKQIWESKAQTEVQLQQkvcdTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSN--- 2331
Cdd:TIGR02168  914 RRELEELrEKLAQLELRLEGLEVRIDN----LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnl 989

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|...
gi 374532817  2332 -SLEKCKEQKGNLEgIIRQQEADIQNSKFSYEQLETDLqaSRELTSRLHEEIN 2383
Cdd:TIGR02168  990 aAIEEYEELKERYD-FLTAQKEDLTEAKETLEEAIEEI--DREARERFKDTFD 1039
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1170-1993 1.41e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 1.41e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1170 KILALEKEKEQLQKKLQEALTSRKAILKKAQEKErhlrEELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsi 1249
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-- 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1250 dgklpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASAlqggtSVAQIKAQLKEIEAEKVELELK 1329
Cdd:TIGR02168  307 --------LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE-----ELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1330 VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKK 1409
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-LKELQAELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1410 EEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMqAKEHDERIKQLQVELCEMKQKPEEI-GEESRAKQQIQR 1488
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLsGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1489 K--------------LQAALISRKEALKENKSLQEELSLARGTIERLT-KSLADVESQVSAQNKEKDTVLGRLALLQEER 1553
Cdd:TIGR02168  532 DegyeaaieaalggrLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDsIKGTEIQGNDREILKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1554 DKLITEMDRSLlenqSLSSSCESLKLALEGL----------TEDKEKL---------VKEIESLKSSKIAESTEWQEKHK 1614
Cdd:TIGR02168  612 PKLRKALSYLL----GGVLVVDDLDNALELAkklrpgyrivTLDGDLVrpggvitggSAKTNSSILERRREIEELEEKIE 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1615 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKI 1694
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1695 LELEEENDRLrAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvsk 1774
Cdd:TIGR02168  768 ERLEEAEEEL-AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----- 841

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1775 qanlEATEKHDNQTNVTEEGTQSIPGETEEQDSLsmstrptcsesvpsaksanpavskdfssHDEINNYLQQIDQLKERI 1854
Cdd:TIGR02168  842 ----DLEEQIEELSEDIESLAAEIEELEELIEEL----------------------------ESELEALLNERASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1855 AGLEEEKQKnkefsqtLENEKNTLLSQISTKDGELKMLQEEVTKMNL----LNQQIQEELSRVTKLKETAEEEKDDLEER 1930
Cdd:TIGR02168  890 ALLRSELEE-------LSEELRELESKRSELRRELEELREKLAQLELrlegLEVRIDNLQERLSEEYSLTLEEAEALENK 962

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 374532817  1931 LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1993
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 814-1655 2.02e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 2.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   814 DVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEvLEGAERVRHISSKVEELSQALSQKELEitKMDQLLLEKKRD 893
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEKE--ALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   894 VETLQQTIEEKDQQVTEISFSMTEKMVQLNE-----------EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSS 962
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEElnkkikdlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   963 GLKQNYDEMspagQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESK---KEIPLSETER 1039
Cdd:TIGR02169  326 KLEAEIDKL----LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKdyrEKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1040 GEVEEDKENKEYSEKCVTSKCQEIEIYLKQtISEKEVELQHIRKDLEEKLAAEE----QFQALVKQMNQTLQDKTNQIDL 1115
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAIAG-IEAKINELEEEKEDKALEIKKQEwkleQLAADLSKYEQELYDLKEEYDR 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1116 LQAEISENQAIIQKLITSNTDASD--GDSVALVKETVVISPPCTGSSEHWKPELEEKILALEK-----------EKEQLQ 1182
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEErvRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVaagnrlnnvvvEDDAVA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1183 KKLQEALTSRKA------ILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKE--NENIGDQL--------RQLQIQVR 1246
Cdd:TIGR02169  561 KEAIELLKRRKAgratflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafKYVFGDTLvvedieaaRRLMGKYR 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1247 E-SIDGKLpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESnLCPDWPSHSEDASALQGGTS-----VAQIKAQLKEIE 1320
Cdd:TIGR02169  641 MvTLEGEL----FEKSGAMTGGSRAPRGGILFSRSEPAELQR-LRERLEGLKRELSSLQSELRrienrLDELSQELSDAS 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1321 AEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHlRELQPKLD 1400
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA-RLSHSRIP 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1401 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIGEES 1480
Cdd:TIGR02169  795 EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI----DLKEQIKSIEKEIENLNGKKEELEEEL 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1481 RAKQQIQRKLQAALISRKealKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERdklitem 1560
Cdd:TIGR02169  871 EELEAALRDLESRLGDLK---KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK------- 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1561 dRSLLENQSLSSSCESLKLALEGLTEDKEKL----VKEIESLKSSKiAESTEWQEKHKELQKEYEILLQSYENVSNEAER 1636
Cdd:TIGR02169  941 -GEDEEIPEEELSLEDVQAELQRVEEEIRALepvnMLAIQEYEEVL-KRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018

                          890       900
                   ....*....|....*....|
gi 374532817  1637 I-QHVVEAVRQEKQELYGKL 1655
Cdd:TIGR02169 1019 VfMEAFEAINENFNEIFAEL 1038
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2012-2612 2.75e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.97  E-value: 2.75e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2012 AKELQELLKEKQQEVKQLQKDciRYQEKISALERTVKALEfvqtesqkdleitkENLAQAVEHRKKAQAELASFKVLLDD 2091
Cdd:COG1196   215 YRELKEELKELEAELLLLKLR--ELEAELEELEAELEELE--------------AELEELEAELAELEAELEELRLELEE 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2092 TQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV 2169
Cdd:COG1196   279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2170 TLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRvideakkwerkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMS 2249
Cdd:COG1196   359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEEL 423

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2250 IHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDL 2329
Cdd:COG1196   424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2330 SNSLEKCKEQKGNLE-GIIRQQEADIQNSKFSYEQ-LETDLQASRELTSRLHEEInmkEQKIISLLSGKEEAiQVAIAEL 2407
Cdd:COG1196   504 EGFLEGVKAALLLAGlRGLAGAVAVLIGVEAAYEAaLEAALAAALQNIVVEDDEV---AAAAIEYLKAAKAG-RATFLPL 579

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2408 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLktikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQ 2487
Cdd:COG1196   580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL----LGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2488 LEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDsQQKQLLEVQLQQN 2567
Cdd:COG1196   656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL-EEEALEEQLEAER 734

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*
gi 374532817 2568 KELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESL 2612
Cdd:COG1196   735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 764-1125 3.67e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 3.67e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  764 VTELRAQVKQLEmnlAEAERQRRldYesqtahdnllteqihsLSIEAKSKDVKIEVLQNELDDVQLQfseqstlIRSLQS 843
Cdd:COG1196   195 LGELERQLEPLE---RQAEKAER--Y----------------RELKEELKELEAELLLLKLRELEAE-------LEELEA 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 923
Cdd:COG1196   247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRkLQAA 1003
Cdd:COG1196   327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-LEEL 405

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1004 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEysekcvtskcqeieiylkqtisEKEVELQHIRK 1083
Cdd:COG1196   406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA----------------------ELEEEEEALLE 463

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 374532817 1084 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1125
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 48-930 4.94e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 4.94e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817    48 EDVQERLAYAEQLVVELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQpaqsstemEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI--------SRLEQQKQILRERLANLERQLEELE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   208 QTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLvtqadveTEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 287
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELESLEAEL-------EELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   288 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREE-SKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELES 366
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   367 RYSALEQKHKAEMEEKTShILSLQKTGQELQSACDALKDQNSKLLQDKN------------EQAVQSA--QTIQQLEDQL 432
Cdd:TIGR02168  476 ALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGvlselisvdegyEAAIEAAlgGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   433 QQKSKEISQFLnrlplQQHETASQTSFPdvynegtqaVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQ 512
Cdd:TIGR02168  555 LNAAKKAIAFL-----KQNELGRVTFLP---------LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSY 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   513 I--------TLLEAQNRTGEADREVSEISIV-DIANKRSSSAEESGQDVLeNTFSQKhKELSVLLLEMKEAQEEIAFLKL 583
Cdd:TIGR02168  621 LlggvlvvdDLDNALELAKKLRPGYRIVTLDgDLVRPGGVITGGSAKTNS-SILERR-REIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   584 QLQgkRAEEADHEVLDQKEMKQMEGEGIapikmkvfledtgqdfplmpNEESSLPAVEKEQASTEHQSRTSEEISLndag 663
Cdd:TIGR02168  699 ALA--ELRKELEELEEELEQLRKELEEL--------------------SRQISALRKDLARLEAEVEQLEERIAQL---- 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   664 velkstkqdgdkslsavpdigqchQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSA 743
Cdd:TIGR02168  753 ------------------------SKELTELEAEIEELEERLEEAEE----ELAEAEAEIEELEAQIEQLKEELKALREA 804

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   744 FTALSEErdqlLSQVKELsmVTELRAQVKQLEMNLAEAERQ-RRLDYESQTahdnlLTEQIHSLSIEAKSKDVKIEVLQN 822
Cdd:TIGR02168  805 LDELRAE----LTLLNEE--AANLRERLESLERRIAATERRlEDLEEQIEE-----LSEDIESLAAEIEELEELIEELES 873

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   823 ELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKR----DVETLQ 898
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLTL 953

                          890       900       910
                   ....*....|....*....|....*....|..
gi 374532817   899 QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLG 930
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIKELG 985
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1500-2093 1.17e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 1.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1500 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD---RSLLENQSLSSSCES 1576
Cdd:PRK03918  163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1577 LKLALEGLTEDKEKL---VKEIESLKSSKIAESTEWQEKHKELQ------KEYEILLQSYENVSNEAERIQHVVEAVRQE 1647
Cdd:PRK03918  243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1648 KQELYGKLRstEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPagdtakecmetllssna 1727
Cdd:PRK03918  323 INGIEERIK--ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG----------------- 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1728 smkEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvSKQANLEATEKHDNQTNV-----TEEGTQSIPGET 1802
Cdd:PRK03918  384 ---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK---ELKKAIEELKKAKGKCPVcgrelTEEHRKELLEEY 457

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1803 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKEriagLEEE-KQKNKEFSQTLENEKNTLLSQ 1881
Cdd:PRK03918  458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE----LEEKlKKYNLEELEKKAEEYEKLKEK 533

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1882 ISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLES 1961
Cdd:PRK03918  534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYN 602

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1962 EMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKI 2040
Cdd:PRK03918  603 EYLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSREL 675

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 374532817 2041 SALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2093
Cdd:PRK03918  676 AGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 688-1261 1.69e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  688 QDELERLKSQILELElnfhKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKelsmvtEL 767
Cdd:COG1196   238 EAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------RL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  768 RAQVKQLEMNLAEAERQRrldyESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN 847
Cdd:COG1196   308 EERRRELEERLEELEEEL----AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  848 KESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKF 927
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEAELEEEEE 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  928 SLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEelqhefdllkKENEQRKRKLQAALInr 1007
Cdd:COG1196   460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA----------ALLLAGLRGLAGAVA-- 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1008 kELLQRVSRLEEELANLKDESKKEIPLSETERGE--VEEDKENKEysekcvtskcqeieiyLKQTISEKEVELQHIRKDL 1085
Cdd:COG1196   528 -VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAaaIEYLKAAKA----------------GRATFLPLDKIRARAALAA 590

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1086 EEKLAAEEQFQALVKQMNQTLQDK-TNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWK 1164
Cdd:COG1196   591 ALARGAIGAAVDLVASDLREADARyYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1165 PELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQ 1244
Cdd:COG1196   671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750

                         570
                  ....*....|....*..
gi 374532817 1245 VRESIDGKLPSTDQQES 1261
Cdd:COG1196   751 EALEELPEPPDLEELER 767
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1847-2629 3.40e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.24  E-value: 3.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1847 IDQLKERIAGLEEEKQKNKEFSQTLE-----------NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTK 1915
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKekreyegyellKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1916 LKETAEEEKDDLEERLMNQLaelngsignycqdvtdaQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEy 1995
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1996 lekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHR 2075
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD-------KEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2076 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsQMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRR 2155
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWK----LEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2156 EKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRV---IDEAKKWERKFSDAIQS------ 2226
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVaagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2227 -----------KEEEIRLKEDNCS--------VLKDQLRQMSIHMEE--LKINISRLEHDKQ-------------IWESK 2272
Cdd:TIGR02169  550 nnvvveddavaKEAIELLKRRKAGratflplnKMRDERRDLSILSEDgvIGFAVDLVEFDPKyepafkyvfgdtlVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2273 AQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2352
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2353 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQqhdkEIKELENLLSQEEEenivl 2432
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL--------SSLEQEIENVKS----ELKELEARIEELEE----- 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2433 eeenkkavdKTNQLMETLKTIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL---IQEAAAE 2509
Cdd:TIGR02169  773 ---------DLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQELQEQ 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2510 NNKLKEEIRGLRSHMDDLNSENAKLDAELiqyredlnqvitikdsqqkqllevqlqqnKELENKYAKLEEKLKESEEANE 2589
Cdd:TIGR02169  842 RIDLKEQIKSIEKEIENLNGKKEELEEEL-----------------------------EELEAALRDLESRLGDLKKERD 892

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 374532817  2590 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE 2629
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 640-1235 5.51e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 5.51e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   640 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 719
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   720 AKEISNLNQLIEEFKKNADNNssaftaLSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLL 799
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDK------IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   800 TEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL-------EGAERVRHISSKVEELSQA 872
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   873 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 952
Cdd:pfam15921  477 LRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   953 QVEEDNEVSSGLKQNYDEMSP----------AGQISKEELQ----------HEFDLLKKENEQRKRKLQAAL----INRK 1008
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEkeindrrlelQEFKILKDKKDAKIRELEARVsdleLEKV 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1009 ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY---LKQTISEKEVELQHIRKDL 1085
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTL 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1086 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEisenqaiIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1165
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK-------IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1166 ELEEKILALEkekeqlQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1235
Cdd:pfam15921  789 AGELEVLRSQ------ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPG 852
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 761-1492 7.96e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 7.96e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   761 LSMVTELRAQVKQLEMNLAEAER-----QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVlQNELDDVQLQFSEQS 835
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEeleklTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRV-KEKIGELEAEIASLE 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   836 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEisfsM 915
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE----T 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   916 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQnydemspagqiSKEELQHEFDLLKKENEQ 995
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-----------KINELEEEKEDKALEIKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   996 RKRKLQAALINRKELLQRVSRLEEELANLKDE---SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTIS 1072
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEYDRVEKElskLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGS 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1073 EKE-----VE------LQHIRKDLEEKLAAEEQFQALVK----------QMNQTLQDKT---------NQIDLL----QA 1118
Cdd:TIGR02169  533 VGEryataIEvaagnrLNNVVVEDDAVAKEAIELLKRRKagratflplnKMRDERRDLSilsedgvigFAVDLVefdpKY 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1119 EISENQAIIQKLITSNTDASD--GDSVALVK---ETVVISPPCTGSS------EHWKPELEEKILALEKEKEQLQKKLQE 1187
Cdd:TIGR02169  613 EPAFKYVFGDTLVVEDIEAARrlMGKYRMVTlegELFEKSGAMTGGSraprggILFSRSEPAELQRLRERLEGLKRELSS 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1188 ALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKlpsTDQQESCSSTPG 1267
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK---SELKELEARIEE 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1268 LEEPLFKATEQhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQL 1347
Cdd:TIGR02169  770 LEEDLHKLEEA------------------LNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1348 QEqinkqglEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAA 1426
Cdd:TIGR02169  832 EK-------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 374532817  1427 LTKIQTEIIEQEDLIKALHTQLEMQAkehdERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQA 1492
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALE----EELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1844-2344 8.58e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.70  E-value: 8.58e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1844 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLKETAEEE 1923
Cdd:PRK03918  230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDE 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1924 KDDLEERLMNQLAELNGsIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE------EEKQQLVKEKTKVESEIRKEYLE 1997
Cdd:PRK03918  309 LREIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTPE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1998 KIQGAQKEPGNKShaKELQELLKEKQQEVKQLQKDCIRYQEKISALER------------TVKALEFVQTESQKDLEITK 2065
Cdd:PRK03918  388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIE 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2066 ENLAQAVEHRKKAQAELASFKVLLddtqsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2145
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2146 MQ------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL----QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2215
Cdd:PRK03918  541 IKslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2216 werkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHdkqiweskaqtevqlqqkvcdtlqgenkell 2295
Cdd:PRK03918  621 --------LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY------------------------------- 661

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 374532817 2296 sqlEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2344
Cdd:PRK03918  662 ---EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 48-613 9.41e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 9.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   48 EDVQERLAyaeqlvvELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:COG1196   182 EATEENLE-------RLEDILGELERQL----EPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEE 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:COG1196   251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  208 QTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 287
Cdd:COG1196   331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  288 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKL--SFHNLQEEMHHLLEQFEQAGQAQAELE 365
Cdd:COG1196   411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALleLLAELLEEAALLEAALAELLEELAEAA 490

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  366 SRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQA---------VQSAQTIQQLEDQLQQKS 436
Cdd:COG1196   491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAlaaalqnivVEDDEVAAAAIEYLKAAK 570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  437 KEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELK--AENEKLSSQIT 514
Cdd:COG1196   571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRraVTLAGRLREVT 650

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  515 LLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEAD 594
Cdd:COG1196   651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                         570
                  ....*....|....*....
gi 374532817  595 HEVLDQKEMKQMEGEGIAP 613
Cdd:COG1196   731 EAEREELLEELLEEEELLE 749
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2225-2776 1.34e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 1.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2225 QSKEEEIRLKEDNCSVLKDQLRQMSIhmEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2304
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2305 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2384
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2385 KEQKIISLLSGKEEA-------------IQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLK 2451
Cdd:COG1196   370 AEAELAEAEEELEELaeellealraaaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2452 TIKK---ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSII-LEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2527
Cdd:COG1196   450 EEAEleeEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2528 NSENAKLDAELIQYREDLNQVITIKDSQQ-KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2606
Cdd:COG1196   530 IGVEAAYEAALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2607 KEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLK 2686
Cdd:COG1196   610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2687 KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKY 2766
Cdd:COG1196   690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769

                         570
                  ....*....|
gi 374532817 2767 DASLKELAQL 2776
Cdd:COG1196   770 ERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2056-2667 1.80e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2056 ESQKDLEITKENLAQA----VEHRK-----KAQAELAsfkvllddtqsEAARVLADNLKLKK-ELQSNKESVKSQMKQKD 2125
Cdd:COG1196   176 EAERKLEATEENLERLedilGELERqleplERQAEKA-----------ERYRELKEELKELEaELLLLKLRELEAELEEL 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2126 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAftksmssLQDD 2205
Cdd:COG1196   245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE-------LEER 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2206 RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2285
Cdd:COG1196   318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2286 TLQgENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE 2365
Cdd:COG1196   398 LAA-QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2366 TDLQASRELTSRLHEEINMKEQkIISLLSGKEEAIQvAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQ 2445
Cdd:COG1196   477 AALAELLEELAEAAARLLLLLE-AEADYEGFLEGVK-AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2446 LMETLKTIKKENIQQKAQLDSF-----VKSMSSLQNDRDRIVGDYQQLEERHLSIILE-KDQLIQEAAAENNKLKEEIRG 2519
Cdd:COG1196   555 DDEVAAAAIEYLKAAKAGRATFlpldkIRARAALAAALARGAIGAAVDLVASDLREADaRYYVLGDTLLGRTLVAARLEA 634

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2520 LRSHMDDLNSENAKLDAELIQyREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQ 2599
Cdd:COG1196   635 ALRRAVTLAGRLREVTLEGEG-GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 374532817 2600 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRlsalfSSSQKRIAELEEEL 2667
Cdd:COG1196   714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-----EELERELERLEREI 776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1838-2622 2.17e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 2.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1838 DEINNYLQQIDQLKERIAGLEEEKQKN-KEFSQTLENEKNTLLSQISTKDGELKMLQEEVTK-----------MNLLNQQ 1905
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAKleaeidkllaeIEELERE 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1906 IQEELSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKT 1985
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELED-LRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1986 KVESEIrkeylEKIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEItK 2065
Cdd:TIGR02169  424 DLNAAI-----AGIEAKINE--LEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE-A 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2066 ENLAQAVEHRkkaQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ----KDEDL---------ERRL 2132
Cdd:TIGR02169  496 EAQARASEER---VRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvvEDDAVakeaiellkRRKA 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2133 EQAEEKHLKEKKNMQEKLDALRREKVHleetigEIQVTLNKKDKEVQQ----------LQENLDSTVTQLAAFtkSMSSL 2202
Cdd:TIGR02169  573 GRATFLPLNKMRDERRDLSILSEDGVI------GFAVDLVEFDPKYEPafkyvfgdtlVVEDIEAARRLMGKY--RMVTL 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2203 QDD----RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDncsvLKDQLRQMSIHMEELKiNISRLEHDKQIWESKAQTEVQ 2278
Cdd:TIGR02169  645 EGElfekSGAMTGGSRAPRGGILFSRSEPAELQRLRER----LEGLKRELSSLQSELR-RIENRLDELSQELSDASRKIG 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2279 LQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEadIQNSK 2358
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEIQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2359 FSYEQLETDLQASRELTSRLHEEINMKEQKiisllsgkeeaiqvaiaelRQQHDKEIKELENLLsqeeEENIVLEEENKK 2438
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLE-------------------KEYLEKEIQELQEQR----IDLKEQIKSIEK 854

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2439 AVDKTNQLMETLKTIKKENIQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAENNKLKEEIR 2518
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLE---SRLGDLKKERDELEAQLRELERK-----------IEELEAQIEKKRKRLS 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2519 GLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK-QLLEVQLQQNKELENKYAKLEeklkeseeanEDLRRSFNA 2597
Cdd:TIGR02169  921 ELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAElQRVEEEIRALEPVNMLAIQEY----------EEVLKRLDE 990

                          810       820
                   ....*....|....*....|....*
gi 374532817  2598 LQEEKQDLSKEIESLKVSISQLTRQ 2622
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1632-2407 3.69e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 3.69e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1632 NEAERIQHVVEAVRQ-EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHP 1710
Cdd:TIGR02169  208 EKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1711 AGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDnqtnv 1790
Cdd:TIGR02169  288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL----- 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1791 tEEGTQSIPGETEEQDSLSMSTRptcsesvpsaksanpavskdfsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1870
Cdd:TIGR02169  363 -KEELEDLRAELEEVDKEFAETR------------------------DELKDYREKLEKLKREINELKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1871 LENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLmnqlaelngsignycqdvt 1950
Cdd:TIGR02169  418 LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY------------------- 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1951 daqiknELLESEMKNLKKCVSELEEEKQQLVKEKT--KVESEIRKEYLEKIQGAQKEPG--NKSHAKELQELLKEKQQEV 2026
Cdd:TIGR02169  479 ------DRVEKELSKLQRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGTVAQLGsvGERYATAIEVAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2027 ----KQLQKDCIRYQEKISALERTVKALEFVQTEsQKDLEITKEN-----LAQAVEHRKKAQaelASFKVLLDDT----Q 2093
Cdd:TIGR02169  553 vvedDAVAKEAIELLKRRKAGRATFLPLNKMRDE-RRDLSILSEDgvigfAVDLVEFDPKYE---PAFKYVFGDTlvveD 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2094 SEAARVLADNLKL--------------------KKELQSNKESVKSQMKQKDEDLErRLEQAEEKHLKEKKNMQEKLDAL 2153
Cdd:TIGR02169  629 IEAARRLMGKYRMvtlegelfeksgamtggsraPRGGILFSRSEPAELQRLRERLE-GLKRELSSLQSELRRIENRLDEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2154 RREKVHLEETIGEIQvtlnkkdKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQSKEEEIRL 2233
Cdd:TIGR02169  708 SQELSDASRKIGEIE-------KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR----IEELEEDLHK 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2234 KEDNCSVLKDQLRQMSI-----HMEELKINISRLE----HDKQIWESKAQTEVQLQQKVcDTLQGENKELLSQLEETRHL 2304
Cdd:TIGR02169  777 LEEALNDLEARLSHSRIpeiqaELSKLEEEVSRIEarlrEIEQKLNRLTLEKEYLEKEI-QELQEQRIDLKEQIKSIEKE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2305 YHSSQNELAKLESELKSLKDQLTDLSnslekckEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2384
Cdd:TIGR02169  856 IENLNGKKEELEEELEELEAALRDLE-------SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928

                          810       820
                   ....*....|....*....|...
gi 374532817  2385 KEQKIISLLSGKEEAIQVAIAEL 2407
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPEEEL 951
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 560-1250 4.53e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.77  E-value: 4.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   560 KHKELSVLLLEMKEAQEEIAFLKLQLqgkraEEADHEVLDQKEMKQMEGEGIAPIKMKVFledtgqdfplmpneesslpa 639
Cdd:TIGR02168  223 RELELALLVLRLEELREELEELQEEL-----KEAEEELEELTAELQELEEKLEELRLEVS-------------------- 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   640 vEKEQASTEHQSR---TSEEISlndagvELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYE--- 713
Cdd:TIGR02168  278 -ELEEEIEELQKElyaLANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEelk 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   714 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEmnlaeaERQRRLDYESQ 792
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLE------DRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   793 TAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQ- 871
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGf 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   872 -----ALSQKELEITKMDQLLLEK-------KRDVET-----LQQTIEEKDQQVTEISFSMTEK-----------MVQLN 923
Cdd:TIGR02168  505 segvkALLKNQSGLSGILGVLSELisvdegyEAAIEAalggrLQAVVVENLNAAKKAIAFLKQNelgrvtflpldSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   924 EEKFSLGVEIKTLKEQLNLLSRAEEAKK----------------EQVEEDNEVSSGLKQNY-------DEMSPAGQISKE 980
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvDDLDNALELAKKLRPGYrivtldgDLVRPGGVITGG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   981 ELQHEFDLLK-----KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKC 1055
Cdd:TIGR02168  665 SAKTNSSILErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1056 VTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAE---EQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLit 1132
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL-- 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1133 SNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI---LKKAQEKERHLREE 1209
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLeeaLALLRSELEELSEE 902

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 374532817  1210 LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESID 1250
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2175-2928 4.63e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 4.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2175 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERkfSDAIQSKEEEIRLKEdncsvLKDQLRQMSIHMEE 2254
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYE-----LLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2255 LKINISRLEhdkqiwESKAQTEVQLQQKVCDTlqGENKELLSQLEEtrHLYHSSQNELAKLESELKSLKDQLTDLSNSLE 2334
Cdd:TIGR02169  242 IERQLASLE------EELEKLTEEISELEKRL--EEIEQLLEELNK--KIKDLGEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2335 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSgKEEAIQVAIAELRQQHDKE 2414
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-ELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2415 IKELENL-----------------LSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQND 2477
Cdd:TIGR02169  391 REKLEKLkreinelkreldrlqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2478 RDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENA---KLDAELIQYRED---------- 2544
Cdd:TIGR02169  471 LYDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaag 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2545 --LNQVITIKDSQQKQLLEVqLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQ 2622
Cdd:TIGR02169  547 nrLNNVVVEDDAVAKEAIEL-LKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2623 VTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSqkRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNE 2702
Cdd:TIGR02169  626 VEDIEAARRLMGKYRMVTLEGELFEKSGAMTGGS--RAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2703 TETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKrkydaslKELAQLKEQglL 2782
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELE-------ARIEELEED--L 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2783 NRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRK 2862
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK 854

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2863 SEEG----KQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQE 2928
Cdd:TIGR02169  855 EIENlngkKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA 924
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-531 7.97e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 7.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   47 QEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGgtvlptep 126
Cdd:COG1196   332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE-------- 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  127 QSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQpAQSSTEMEEFVMMKQQLQEKEEFISTLQAQL 206
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE-AELEEEEEALLELLAELLEEAALLEAALAEL 482

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  207 SQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQ-------------ADVETEMQQKL--------RVLQRK 265
Cdd:COG1196   483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGavavligveaayeAALEAALAAALqnivveddEVAAAA 562

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  266 LEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEkmELEVAERKLSFHNLQE 345
Cdd:COG1196   563 IEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLG--RTLVAARLEAALRRAV 640

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  346 EMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTI 425
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  426 QQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVynegtqavTEENIASLQKRVVELENEKGAL----LLSSIELEE 501
Cdd:COG1196   721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEELP--------EPPDLEELERELERLEREIEALgpvnLLAIEEYEE 792

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 374532817  502 LKAENEKLSSQI-TLLEA----QNRTGEADREVSE 531
Cdd:COG1196   793 LEERYDFLSEQReDLEEAretlEEAIEEIDRETRE 827
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1837-2550 8.76e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 61.99  E-value: 8.76e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1837 HDEINNYLQQIDQL-KERIAGLEEEKQKNKEFSQTLENEKNTLLSQIS----TKDGELKMlQEEVTKMN----LLNQQIQ 1907
Cdd:TIGR01612 1050 HTSIYNIIDEIEKEiGKNIELLNKEILEEAEINITNFNEIKEKLKHYNfddfGKEENIKY-ADEINKIKddikNLDQKID 1128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1908 EELSRVTKLKETAEEEKDDLEERLmnqlaelngsigNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK------QQLV 1981
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKAQI------------NDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKniydeiKKLL 1196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1982 KEKTKVESEirKEYLEKIQGAqkepgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERTVKALEFVQTESQKD 2060
Cdd:TIGR01612 1197 NEIAEIEKD--KTSLEEVKGI-----NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAyIEDLDEIKEKSPEIENEMGIE 1269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2061 LEITKENLAQAVEHRKKAQAELASFK--VLLDDTQSEAARVLADNLK------LKKELQSNKesvkSQMKQKDEDLERRL 2132
Cdd:TIGR01612 1270 MDIKAEMETFNISHDDDKDHHIISKKhdENISDIREKSLKIIEDFSEesdindIKKELQKNL----LDAQKHNSDINLYL 1345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2133 EQ-AEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDstvtqLAAFTKSMSSLQDDRDrvID 2211
Cdd:TIGR01612 1346 NEiANIYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDIN-----LEECKSKIESTLDDKD--ID 1418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2212 EAKKWERKFSDAIQSKEEEI-----RLKEDNCSVLK-----DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEvqlQQ 2281
Cdd:TIGR01612 1419 ECIKKIKELKNHILSEESNIdtyfkNADENNENVLLlfkniEMADNKSQHILKIKKDNATNDHDFNINELKEHID---KS 1495

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2282 KVCDTLQGENKEllsQLEETRHLYHSSQNELAKL-----ESELKSLKDQLTDLSNSL-EKCKEQKGNL---EGIIRQQEA 2352
Cdd:TIGR01612 1496 KGCKDEADKNAK---AIEKNKELFEQYKKDVTELlnkysALAIKNKFAKTKKDSEIIiKEIKDAHKKFileAEKSEQKIK 1572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2353 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISllsgkeeaiqvaIAELRQQHDKEIKELENLLSQEEE----E 2428
Cdd:TIGR01612 1573 EIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLK------------ISDIKKKINDCLKETESIEKKISSfsidS 1640

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2429 NIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQqleerhLSIIlekDQLIQEAAA 2508
Cdd:TIGR01612 1641 QDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYE------IGII---EKIKEIAIA 1711

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 374532817  2509 ENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVIT 2550
Cdd:TIGR01612 1712 NKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNT 1753
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2309-2778 1.10e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.19  E-value: 1.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2309 QNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE--EINMKE 2386
Cdd:TIGR04523  151 EKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISElkKQNNQL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2387 QKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDS 2466
Cdd:TIGR04523  231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2467 FVKSmsSLQNDRDRIVGDYQQLEERHLSIilekdqliqeaaaenNKLKEEIRGLRSHMDDLNSENAKLDAELiqyREDLN 2546
Cdd:TIGR04523  311 ELKS--ELKNQEKKLEEIQNQISQNNKII---------------SQLNEQISQLKKELTNSESENSEKQREL---EEKQN 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2547 QVITIKDSQQKQLlevqlQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2626
Cdd:TIGR04523  371 EIEKLKKENQSYK-----QEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2627 QEEGTlglyhaqlkVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETETA 2706
Cdd:TIGR04523  446 TNQDS---------VKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK-EKELKKLNEEKKELEEKVKDL 515

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 374532817  2707 EERVAELARDLVEMEQKLLMVTKENKGLTAQIQS--FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2778
Cdd:TIGR04523  516 TKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQE 589
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1847-2162 1.15e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1847 IDQLKERIAGLEEEKQKNKEFsQTLENEKNTL-----LSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1921
Cdd:COG1196   195 LGELERQLEPLERQAEKAERY-RELKEELKELeaellLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1922 EEKDDLEERLmnqlaelngsignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG 2001
Cdd:COG1196   274 LELEELELEL------------------EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2002 AQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITK---ENLAQAVEHRKKA 2078
Cdd:COG1196   336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAaqlEELEEAEEALLER 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2079 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKV 2158
Cdd:COG1196   416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495


                  ....
gi 374532817 2159 HLEE 2162
Cdd:COG1196   496 LLEA 499
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 688-1216 1.20e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  688 QDELERLKSQILELELNFHKAQE---IYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SM 763
Cdd:COG1196   266 EAELEELRLELEELELELEEAQAeeyELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELeEE 345

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  764 VTELRAQVKQLEMNLAEAERQRRLDYESQTAHDnlltEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 843
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAE----EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM-TEKMVQL 922
Cdd:COG1196   422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLlLLLEAEA 501

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  923 NEEKFSLGVEIKTLKEQLNLLSRA------EEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISkeelqhefDLLKKENEQR 996
Cdd:COG1196   502 DYEGFLEGVKAALLLAGLRGLAGAvavligVEAAYEAALEAALAAALQNIVVEDDEVAAAAI--------EYLKAAKAGR 573

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  997 KRKLQAALINRKELLQRVSRLEEEL-------ANLKDESKKEIPLSETERGE--VEEDKENKEYSEKCVTSKCQEIEIYL 1067
Cdd:COG1196   574 ATFLPLDKIRARAALAAALARGAIGaavdlvaSDLREADARYYVLGDTLLGRtlVAARLEAALRRAVTLAGRLREVTLEG 653

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1068 KQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVK 1147
Cdd:COG1196   654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 374532817 1148 ETVVISPPCTGSSEHwkPELEEKILALEKEKEQLQKKLQEALTSRK--------AILKKAQEKERHlrEELKQQKDD 1216
Cdd:COG1196   734 REELLEELLEEEELL--EEEALEELPEPPDLEELERELERLEREIEalgpvnllAIEEYEELEERY--DFLSEQRED 806
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 871-1768 1.79e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 60.76  E-value: 1.79e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   871 QALSQKELEITKMDQLL---LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKfslgVEIKTLKEQLNLLSRAE 947
Cdd:pfam02463  146 IIAMMKPERRLEIEEEAagsRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKE----QAKKALEYYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   948 EAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 1027
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1028 SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTIS--EKEVELQHIRKDLEEKLAAEEQFQALVKQMNQT 1105
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKEleIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1106 LQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDsvalvketvvisppctgssEHWKPELEEKILALEKEKEQLQKKL 1185
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL-------------------EDLLKEEKKEELEILEEEEESIELK 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1186 QEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSST 1265
Cdd:pfam02463  443 QGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGG 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1266 PGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVF 1345
Cdd:pfam02463  523 RIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1346 QLQEQINKQGLEIESLKTVSHEAEVHAESLQQK--LESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVS--YLSGQLS 1421
Cdd:pfam02463  603 LNLAQLDKATLEADEDDKRAKVVEGILKDTELTklKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKelLEIQELQ 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1422 EKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL 1501
Cdd:pfam02463  683 EKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1502 KENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTvlgrLALLQEERDKLITEMDRSLLENQSLSSSCESLKLAL 1581
Cdd:pfam02463  763 EEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE----LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEEL 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1582 EGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERiqhvvEAVRQEKQELYGKLRSTEAN 1661
Cdd:pfam02463  839 ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE-----KEKEEKKELEEESQKLNLLE 913

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1662 KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHpaGDTAKECMETLLSSNASMKEELERVKMEYE 1741
Cdd:pfam02463  914 EKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER--NKRLLLAKEELGKVNLMAIEEFEEKEERYN 991

                          890       900
                   ....*....|....*....|....*..
gi 374532817  1742 TLSKKFQSLMSEKDSLSEEVQDLKHQI 1768
Cdd:pfam02463  992 KDELEKERLEEEKKKLIRAIIEETCQR 1018
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1166-1657 2.01e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 2.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1166 ELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKerhlREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQV 1245
Cdd:PRK02224  217 ELDEEIERYEEQREQARETRDEA----DEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1246 ---RESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpDWPSHSEDASALQGgtSVAQIKAQLKEIEAE 1322
Cdd:PRK02224  289 eelEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRV--AAQAHNEEAESLRE--DADDLEERAEELREE 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1323 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDE 1401
Cdd:PRK02224  365 AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTARERVEE 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1402 LQKL---------------------ISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKA------LHTQLEMQAK- 1453
Cdd:PRK02224  445 AEALleagkcpecgqpvegsphvetIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAedrierLEERREDLEEl 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1454 --EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVES- 1530
Cdd:PRK02224  525 iaERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADa 604

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1531 ---------QVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLEN-----QSLSSSCESLKLALEGLTEDKEKLVKEIE 1596
Cdd:PRK02224  605 edeierlreKREALAELNDERRERLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERDDLQAEIG 684

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 374532817 1597 SLKSSkIAESTEWQEKHKELQKEYEILLQSYENVSneaeriqhvveavrqEKQELYGKLRS 1657
Cdd:PRK02224  685 AVENE-LEELEELRERREALENRVEALEALYDEAE---------------ELESMYGDLRA 729
PTZ00121 PTZ00121
MAEBL; Provisional
 1593-2387 2.14e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 2.14e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1593 KEIESLKSSKIAESTEWQEKHKELQKEYEilLQSYENVsNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1672
Cdd:PTZ00121 1164 RKAEEARKAEDAKKAEAARKAEEVRKAEE--LRKAEDA-RKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAE 1240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1673 EQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERV---------KMEYETL 1743
Cdd:PTZ00121 1241 EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKAdeakkkaeeAKKADEA 1320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1744 SKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQanleatEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTcSESVPSA 1823
Cdd:PTZ00121 1321 KKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA------EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK-AEEKKKA 1393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1824 KSANPAVSKDFSSHDEINNYL---QQIDQLK---ERIAGLEEEKQKNKEFSQTLENEKNtllSQISTKDGELKMLQEEVT 1897
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAaakKKADEAKkkaEEKKKADEAKKKAEEAKKADEAKKK---AEEAKKAEEAKKKAEEAK 1470

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1898 KMNLLNQQiQEELSRVTKLKETAEEEKDDLEErlmnqlAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK 1977
Cdd:PTZ00121 1471 KADEAKKK-AEEAKKADEAKKKAEEAKKKADE------AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAE 1543

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1978 QQLVKEKTKVESEIRK-EYLEKIQGAQKEpgnkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTE 2056
Cdd:PTZ00121 1544 EKKKADELKKAEELKKaEEKKKAEEAKKA-------EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE 1616

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2057 SQKdleITKENLAQAVEHRKKaqAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK---ESVKSQMKQKDEDLERRLE 2133
Cdd:PTZ00121 1617 EAK---IKAEELKKAEEEKKK--VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKaeeDKKKAEEAKKAEEDEKKAA 1691

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2134 QAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD---KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVI 2210
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEeakKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2211 DEAKKWERKFSDAIQSKEEEIRLKEDNcsVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDtlqgE 2290
Cdd:PTZ00121 1772 EIRKEKEAVIEEELDEEDEKRRMEVDK--KIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLE----E 1845

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2291 NKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQA 2370
Cdd:PTZ00121 1846 ADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYI 1925

                         810
                  ....*....|....*..
gi 374532817 2371 SRELTSRLHEEINMKEQ 2387
Cdd:PTZ00121 1926 KRDAEETREEIIKISKK 1942
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1834-2051 2.17e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.39  E-value: 2.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1834 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEvtkMNLLNQQIQEELSRV 1913
Cdd:COG4942    16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE---LAALEAELAELEKEI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1914 TKLKETAEEEKDDLEERL-----MNQLAELNGSIGNycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1988
Cdd:COG4942    93 AELRAELEAQKEELAELLralyrLGRQPPLALLLSP--EDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 374532817 1989 SEiRKEYLEKIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALE 2051
Cdd:COG4942   171 AE-RAELEALLAELEEE------RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2218-2778 2.18e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 2.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2218 RKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQiwesKAQTEVQLQQKvcdTLQGENKELLSQ 2297
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE----EAQAEEYELLA---ELARLEQDIARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2298 LEETRHLyhssQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSR 2377
Cdd:COG1196   308 EERRREL----EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2378 LHEEINMKEQKIISLLSGKEEAIQV--AIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKK 2455
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAeeALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2456 ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsiiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLD 2535
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLE------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2536 AELIQYREDLNQVITIKDSQQ-KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKV 2614
Cdd:COG1196   538 AALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2615 SISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHH 2694
Cdd:COG1196   618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2695 DAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFG---------------------RSMSSLQNSRD 2753
Cdd:COG1196   698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEelleeealeelpeppdleeleRELERLEREIE 777

                         570       580       590
                  ....*....|....*....|....*....|..
gi 374532817 2754 H-------ANEELDELKRKYDASLKELAQLKE 2778
Cdd:COG1196   778 AlgpvnllAIEEYEELEERYDFLSEQREDLEE 809
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1420-1939 4.09e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 4.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1420 LSEKEAALTKIQTEI--IEQEDLIKALHTqLEMQAKEHDERIKQLQVE---LCEMKQKPEEIGEESRAKQQIQRKLQAAL 1494
Cdd:PRK02224  182 LSDQRGSLDQLKAQIeeKEEKDLHERLNG-LESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELETLEAEI 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1495 ----ISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSL 1570
Cdd:PRK02224  261 edlrETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1571 SSSCESLK---LALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1647
Cdd:PRK02224  341 NEEAESLRedaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE 420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1648 KQELYGKLRSTEANKKETEKQLQEAEQEMEE----------MKEKMRKFAKSKQQKILELEEENDRLRAEVhpagdtake 1717
Cdd:PRK02224  421 RDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEV--------- 491

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1718 cmetllssnASMKEELERVKMEYETlSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANL-EATEKHDNQTNVTEEGTQ 1796
Cdd:PRK02224  492 ---------EEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRETIEEKRERAEELrERAAELEAEAEEKREAAA 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1797 SIPGETEEqdslSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN 1876
Cdd:PRK02224  562 EAEEEAEE----AREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKR 637

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 374532817 1877 TLLSQIStkDGELKMLQEEvtkmnllNQQIQEELSRVTKLKETAEEEKDDLEER---LMNQLAELN 1939
Cdd:PRK02224  638 ELEAEFD--EARIEEARED-------KERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELE 694
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1166-1707 4.54e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 4.54e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1166 ELEEKILALEKEKEQLQK--KLQEALTSRKAILKKAqeKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQI 1243
Cdd:COG1196   197 ELERQLEPLERQAEKAERyrELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1244 QVRESIDgklpstdqqescsstpgleeplfkateqhhtqpvlesnlcpdwpshsedasalqggtSVAQIKAQLKEIEAEK 1323
Cdd:COG1196   275 ELEELEL---------------------------------------------------------ELEEAQAEEYELLAEL 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1324 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHlrelqpKLDELQ 1403
Cdd:COG1196   298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE------ALLEAE 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1404 KLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAK 1483
Cdd:COG1196   372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1484 QQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRS 1563
Cdd:COG1196   452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1564 LLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS-----------SKIAESTEWQEKHKELQKEYEILLQSYENVSN 1632
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 374532817 1633 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1707
Cdd:COG1196   612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 48-960 4.78e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 4.78e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817    48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQkdeaLQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVlptepq 127
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLER----LRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAI------ 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   128 sEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEfvmmkqqlqekeefistLQAQLS 207
Cdd:TIGR02169  243 -ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGE-----------------LEAEIA 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   208 QTQAEQAAQLSSMQQVVREkdaRFETQVRLHEdellqlvtqadvetemqqklrvLQRKLEEHEESLVGRAQVVDLLQQEL 287
Cdd:TIGR02169  305 SLERSIAEKERELEDAEER---LAKLEAEIDK----------------------LLAEIEELEREIEEERKRRDKLTEEY 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   288 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMElevaerklsfhNLQEEMHHLLEQFEQAGQAQAELESR 367
Cdd:TIGR02169  360 AELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN-----------ELKRELDRLQEELQRLSEELADLNAA 428

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   368 YSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEqavqsaqtIQQLEDQLQQKSKEISQFLNRLP 447
Cdd:TIGR02169  429 IAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE--------YDRVEKELSKLQRELAEAEAQAR 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   448 LQQHETASQTSFPDVYNEGTQAV---TEENIASLQKRVVELENEKGAlllssiELEELKAENEKLSSQITLLEAQNRTGE 524
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVAAGN------RLNNVVVEDDAVAKEAIELLKRRKAGR 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   525 AdrevSEISIVDIANKRSSSAEESGQDVLentfsqkhkELSVLLLEMKEAQEEIAFLKLQLQG-KRAEEADHEVLDQKEM 603
Cdd:TIGR02169  575 A----TFLPLNKMRDERRDLSILSEDGVI---------GFAVDLVEFDPKYEPAFKYVFGDTLvVEDIEAARRLMGKYRM 641

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   604 KQMEGEGIAP---IKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAV 680
Cdd:TIGR02169  642 VTLEGELFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEI 721

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   681 PDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKE 760
Cdd:TIGR02169  722 EKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS 801

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   761 lsmvtELRAQVKQLEMNLAEAERQ-RRLDYESQTAHDnllteqihslsiEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 839
Cdd:TIGR02169  802 -----KLEEEVSRIEARLREIEQKlNRLTLEKEYLEK------------EIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   840 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEkM 919
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE-D 943

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|.
gi 374532817   920 VQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEV 960
Cdd:TIGR02169  944 EEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEV 984
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1306-2184 4.95e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 4.95e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1306 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1385
Cdd:pfam02463  161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1386 IagLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1465
Cdd:pfam02463  241 L--LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1466 LCEMKQKpeeigeesrakqqIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1545
Cdd:pfam02463  319 SEKEKKK-------------AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1546 LALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1625
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1626 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1705
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1706 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1785
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1786 NQTNVTEEGTQSIPGETEEQDSLSMstrptcsesVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1865
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRK---------GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1866 EFSQTLENEKNTLLSQISTKDGELKMLQEEVT-KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1944
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQeAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1945 YCQDVTDAQIKNElLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepgnKSHAKELQELLKEKQQ 2024
Cdd:pfam02463  777 AEEREKTEKLKVE-EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK--------EEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2025 EVKQLQKDCIRYQEKISALERTVKALEfvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL 2104
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLL----KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2105 KLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2184
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1064-1929 7.07e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 7.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1064 EIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDAsDGDSV 1143
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL-QKELY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1144 ALVKEtvvisppctgssehwKPELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQ 1223
Cdd:TIGR02168  292 ALANE---------------ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELAEELAELEEKLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1224 FDEQSKENENIGDQLRQLQIQVREsidgklpstDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpSHSEDasal 1303
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEE---------LEEQLETLRSKVAQLELQIASLNNEIERLEARL-----ERLED---- 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1304 qggtSVAQIKAQLKEIEAEKVELELKVSSTtsELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQ 1383
Cdd:TIGR02168  415 ----RRERLQQEIEELLKKLEEAELKELQA--ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1384 LQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEK-------EAALtkiqtEIIEQEDLIKALHTQLE--MQAKE 1454
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAI-----EAALGGRLQAVVVENLNaaKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1455 HDERIKQLQVELCEMKQKPEeigeesrakQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1534
Cdd:TIGR02168  564 FLKQNELGRVTFLPLDSIKG---------TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1535 QNKEK-------------DTVLGRLALLQ--EERDKLITEMDRSLLENQS----LSSSCESLKLALEGLTEDKEKLVKEI 1595
Cdd:TIGR02168  635 LELAKklrpgyrivtldgDLVRPGGVITGgsAKTNSSILERRREIEELEEkieeLEEKIAELEKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1596 ESLKSSKIAESTewqeKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEkqlqeaeQE 1675
Cdd:TIGR02168  715 EQLRKELEELSR----QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE-------AE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1676 MEEMKEKMRKFAKSKQQKILELEEENDRLRAevhpagdtakecmetLLSSNASMKEELERVKMEYETLSKKFQSLMSEKD 1755
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTL---------------LNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1756 SLSEEVQDLKHQIEGNVSKQANLE-ATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKdf 1834
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELEsELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ-- 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1835 sSHDEINNYLQQIDQLKERIAgleEEKQKNKEFSQTLENEKNTLLSQIstkDGELKMLQEEVTKMNLLNQQIQEELSRVT 1914
Cdd:TIGR02168  927 -LELRLEGLEVRIDNLQERLS---EEYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKELGPVNLAAIEEYEELK 999

                          890
                   ....*....|....*
gi 374532817  1915 KLKETAEEEKDDLEE 1929
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTE 1014
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2643-2946 9.30e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 9.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2643 EEEVHRLSALFSSSQKRIAELEEelvcvQKEAAKKVGEIEDKLKK--------ELKHLHHDAGIMRNETETAEERVAELA 2714
Cdd:COG1196   185 EENLERLEDILGELERQLEPLER-----QAEKAERYRELKEELKEleaellllKLRELEAELEELEAELEELEAELEELE 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2715 RDLVEME-------QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2787
Cdd:COG1196   260 AELAELEaeleelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2788 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR----KS 2863
Cdd:COG1196   340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerleRL 419

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2864 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEEL 2943
Cdd:COG1196   420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499


                  ...
gi 374532817 2944 RQE 2946
Cdd:COG1196   500 EAD 502
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1438-2183 9.77e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.21  E-value: 9.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1438 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1514
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKfylRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1515 RGT-IERLTKSLADVESQVSAqnkekdtVLGRLALLQEERDKLITEMDR-SLLENQSLSSSCESLKLALEgltedkeklv 1592
Cdd:pfam15921  168 SNTqIEQLRKMMLSHEGVLQE-------IRSILVDFEEASGKKIYEHDSmSTMHFRSLGSAISKILRELD---------- 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1593 KEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYEnvsneaERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1672
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEII 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1673 EQEMEEMKEKMrkfakskQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLms 1752
Cdd:pfam15921  305 QEQARNQNSMY-------MRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNL-- 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1753 eKDSLSEEVQDL-KHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVS 1831
Cdd:pfam15921  376 -DDQLQKLLADLhKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1832 KDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM----NLLNQQIQ 1907
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLrsrvDLKLQELQ 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1908 EELSRVTKLKETAEE---------EKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQ 1978
Cdd:pfam15921  535 HLKNEGDHLRNVQTEcealklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKD 614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1979 QLVKEKTKVESEIRKEYLEKIQ----GAQKEPGNKSHAKELQELLKE---KQQEVKQLQKDC----IRYQEKISALERTV 2047
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKlvnaGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTT 694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2048 KALEFVQTESQKDLEITKENL-------AQAVEHRKKAQAELASFKVLLDDTQSEaarvladnLKLKKELQSNKESVKSQ 2120
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLksmegsdGHAMKVAMGMQKQITAKRGQIDALQSK--------IQFLEEAMTNANKEKHF 766

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 374532817  2121 MKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQE 2183
Cdd:pfam15921  767 LKEEKNKLSQELSTVA----TEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 551-1441 1.60e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 1.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   551 DVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQkemkqmegegiapikmkvfledtgqdfplm 630
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS------------------------------ 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   631 pneesslpavEKEQASTEHQSR---TSEEISlndagvELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHK 707
Cdd:TIGR02168  278 ----------ELEEEIEELQKElyaLANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   708 AQEIYE---KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEmnlaeaER 783
Cdd:TIGR02168  342 LEEKLEelkEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLE------DR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   784 QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHIS 863
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   864 SKVEELSQalsqkeleITKMDQLLLEKKRDVETLQQTIEEKdqqvteISFsmtekmvqlnEEKFSLGVEIkTLKEQLN-L 942
Cdd:TIGR02168  496 RLQENLEG--------FSEGVKALLKNQSGLSGILGVLSEL------ISV----------DEGYEAAIEA-ALGGRLQaV 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   943 LSRAEEAKKEQVEEDNEVSSG------LKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 1016
Cdd:TIGR02168  551 VVENLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1017 LEEELANLKDESKKEIPLSE-----TERGEVEEDKENKEYSekcVTSKCQEIEIyLKQTISEKEVELQHIRKDLEEKLAA 1091
Cdd:TIGR02168  631 LDNALELAKKLRPGYRIVTLdgdlvRPGGVITGGSAKTNSS---ILERRREIEE-LEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1092 EEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVisppctgssEHWKPELEEKI 1171
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL---------EERLEEAEEEL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1172 LALEKEKEQLQ---KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1248
Cdd:TIGR02168  778 AEAEAEIEELEaqiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES- 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1249 idgklpSTDQQEScsstpgLEEPLFKATEQHHtqpvlesnlcpdwpSHSEDASALQggTSVAQIKAQLKEIEAEKVELEL 1328
Cdd:TIGR02168  857 ------LAAEIEE------LEELIEELESELE--------------ALLNERASLE--EALALLRSELEELSEELRELES 908

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1329 KVSSTTSELTKKSEEVFQLQEQINKQGLEIESLK-TVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKL- 1405
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQeRLSEEYSLTLEEAEALENKIEDDEEEARrRLKRLENKIKELGPVn 988

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|..
gi 374532817  1406 ------ISKKEEDVSYLSGQLSEKEAALTKIQtEIIEQEDLI 1441
Cdd:TIGR02168  989 laaieeYEELKERYDFLTAQKEDLTEAKETLE-EAIEEIDRE 1029
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1392-1608 1.70e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 1.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1392 LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1471
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1472 KPEEIGEESRAKQQIQRKLQAALI----SRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLA 1547
Cdd:COG4942   102 QKEELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 374532817 1548 LLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE 1608
Cdd:COG4942   182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PTZ00121 PTZ00121
MAEBL; Provisional
 1310-1866 2.00e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 2.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1310 AQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTvsHEAEVHAESLQQKLESSQLQIAGL 1389
Cdd:PTZ00121 1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK--EEAKKKADAAKKKAEEKKKADEAK 1397

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1390 EHLRELQPKLDELQKLIS--KKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelc 1467
Cdd:PTZ00121 1398 KKAEEDKKKADELKKAAAakKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD---- 1473

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1468 EMKQKPEEI--GEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1545
Cdd:PTZ00121 1474 EAKKKAEEAkkADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1546 LALLQEERDKLITEMDRSLLENQSLSS-SCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILL 1624
Cdd:PTZ00121 1554 AEELKKAEEKKKAEEAKKAEEDKNMALrKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK 1633

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1625 QSYENVSNEAERIQHvVEAVRQEKQELYGKlRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1704
Cdd:PTZ00121 1634 KVEQLKKKEAEEKKK-AEELKKAEEENKIK-AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1705 RAEVHPAGDTAKECMETLL-SSNASMKEELERVKMEY----ETLSKKFQSLMSEKDSLSEEVQDLKHQI------EGNVS 1773
Cdd:PTZ00121 1712 AEEKKKAEELKKAEEENKIkAEEAKKEAEEDKKKAEEakkdEEEKKKIAHLKKEEEKKAEEIRKEKEAVieeeldEEDEK 1791

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1774 KQANLEATEK--HDNQTNVTEEGTQSIP----------GETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEIN 1841
Cdd:PTZ00121 1792 RRMEVDKKIKdiFDNFANIIEGGKEGNLvindskemedSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFN 1871

                         570       580
                  ....*....|....*....|....*
gi 374532817 1842 NYLQQIDQLKERIAGLEEEKQKNKE 1866
Cdd:PTZ00121 1872 KEKDLKEDDEEEIEEADEIEKIDKD 1896
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1320-1983 2.07e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.95  E-value: 2.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1320 EAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL-EHLRELQPK 1398
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1399 LDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEhderIKQLQVELCEMKQKPEEIGE 1478
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQ----KEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1479 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLIT 1558
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1559 EMDRSLLEnqslsssCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTewQEKHKELQKEYEILLQSYENVSNEAERIQ 1638
Cdd:TIGR04523  268 QLSEKQKE-------LEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWN--KELKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1639 HVVEAVRQEKQELYGKLRSTEANKKETEKqlqeaeqemeemkekmrkfaksKQQKILELEEENDRLraevhpagdtaKEC 1718
Cdd:TIGR04523  339 QLNEQISQLKKELTNSESENSEKQRELEE----------------------KQNEIEKLKKENQSY-----------KQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1719 METLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLeatEKHDNQTNVTEEGTQSI 1798
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL---TNQDSVKELIIKNLDNT 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1799 PGETEEQDSlsmstrpTCSESVPSAKSANPAVSKDFSSH-DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNT 1877
Cdd:TIGR04523  463 RESLETQLK-------VLSRSINKIKQNLEQKQKELKSKeKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKE 535

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1878 LLSQISTKDGELKMLQEEVTKMNL------LNQQIQEELSRVTKLKETAEEEKDDLEER------LMNQLAELNGSIGNY 1945
Cdd:TIGR04523  536 KESKISDLEDELNKDDFELKKENLekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKekekkdLIKEIEEKEKKISSL 615

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 374532817  1946 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKE 1983
Cdd:TIGR04523  616 EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653
PTZ00121 PTZ00121
MAEBL; Provisional
 707-1234 2.73e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.73e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  707 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQ 784
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  785 RRLDYESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 857
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  858 RVRHISSKVEELSQA--LSQKELEITKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 933
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  934 KTLKEqlnlLSRAEEAKKEQVEEDNEVssglKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1013
Cdd:PTZ00121 1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1014 VSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE 1093
Cdd:PTZ00121 1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1094 QFQAlvKQMNQTLQDKTNQIDLLQAEISENQaiiqklitsntdasdgdsvalvketvvisppctgssehwKPELEEKILA 1173
Cdd:PTZ00121 1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 374532817 1174 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1234
Cdd:PTZ00121 1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1585-2162 4.72e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.84  E-value: 4.72e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1585 TEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIqhvvEAVRQEKQELYGKLRSTEANKKE 1664
Cdd:PRK03918  188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI----EELEKELESLEGSKRKLEEKIRE 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1665 TEKQLQEAEQEMEEMKEKM----------------RKFAKSKQQKILELEEENDRLRAEVhpagdtakECMETLLSSNAS 1728
Cdd:PRK03918  264 LEERIEELKKEIEELEEKVkelkelkekaeeyiklSEFYEEYLDELREIEKRLSRLEEEI--------NGIEERIKELEE 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1729 MKEELERVKMEYETLSKKFQSLmSEKDSLSEEVQDLKHQIEGNVSKQANL---EATEKHDNQTNVTEEGTQSIPGETEEQ 1805
Cdd:PRK03918  336 KEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTGLtpeKLEKELEELEKAKEEIEEEISKITARI 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1806 DSLS--MSTRPTCSESVPSAKSANPAVSKDFSSHDE---INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN---T 1877
Cdd:PRK03918  415 GELKkeIKELKKAIEELKKAKGKCPVCGRELTEEHRkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKkesE 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1878 LLSQISTKDgELKMLQEEVTKMNLlnqqiqEELSRVTKLKETAEEEKDDLEERLMNQLAELNgsignycqdvtdaqiKNE 1957
Cdd:PRK03918  495 LIKLKELAE-QLKELEEKLKKYNL------EELEKKAEEYEKLKEKLIKLKGEIKSLKKELE---------------KLE 552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1958 LLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIqgaqkepgnkshaKELQELLKEkQQEVKQLQKDCIRYQ 2037
Cdd:PRK03918  553 ELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL-------------KELEPFYNE-YLELKDAEKELEREE 618

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2038 EKISALERTVKALEFVQTESQKDLEITKENLAQAveHRKKAQAELASFKVLLDDTQSEAARVLADnlklKKELQSNKESV 2117
Cdd:PRK03918  619 KELKKLEEELDKAFEELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAE----LEELEKRREEI 692

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*..
gi 374532817 2118 KSQMKQKDEDLERRLEQAEEKHLKEK--KNMQEKLDALRREKVHLEE 2162
Cdd:PRK03918  693 KKTLEKLKEELEEREKAKKELEKLEKalERVEELREKVKKYKALLKE 739
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 994-1598 6.22e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 6.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  994 EQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEiplsETERGEVEEDKENkeysekcvtskcqeieiyLKQTISE 1073
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEEL----EAELAELEAELEE------------------LRLELEE 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1074 KEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSntdasdgdsvalvketvvis 1153
Cdd:COG1196   279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE-------------------- 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1154 ppctgssehwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQ----------KDDYNRLQEQ 1223
Cdd:COG1196   339 ----------LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELlealraaaelAAQLEELEEA 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1224 FDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASAL 1303
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL--------LEAALA 480

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1304 QGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKK-----SEEVFQLQEQINKQGLEIE-----SLKTVSHEAEVHAE 1373
Cdd:COG1196   481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglAGAVAVLIGVEAAYEAALEaalaaALQNIVVEDDEVAA 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1374 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAK 1453
Cdd:COG1196   561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1454 EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVS 1533
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 374532817 1534 AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQslssscESLKLALEGLTEDKEKLVKEIESL 1598
Cdd:COG1196   721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEE------LPEPPDLEELERELERLEREIEAL 779
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1952-2708 8.41e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 8.41e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1952 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2031
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2032 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2111
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2112 SNKESVKSQMKQKDEDLERRL------EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2186 dstvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHD 2265
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2266 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK--DQLTDLSNSLEKCKEQKGNL 2343
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2344 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS 2423
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2424 QEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLI 2503
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2504 QEAAAE--NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKL 2581
Cdd:pfam02463  727 VQEAQDkiNEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2582 KESEEANEDLRRSFNALQE-EKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEvhrlsalfsSSQKRI 2660
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEqEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQE---------LLLKEE 877

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 374532817  2661 AELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEE 2708
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE 925
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 327-1142 8.85e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 8.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   327 EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHkaemEEKTSHILSLQKTGQELQSACDALKdq 406
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEIEELQKELYALA-- 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   407 nsKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQtsfpdvynEGTQAVTEENIASLQKRVVELE 486
Cdd:TIGR02168  295 --NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL--------EEKLEELKEELESLEAELEELE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   487 NEKGALLLSSIELEElkaENEKLSSQITLLEAQNRTGEADREVSEISIVDIA---NKRSSSAEESGQDVLENTFSQKHKE 563
Cdd:TIGR02168  365 AELEELESRLEELEE---QLETLRSKVAQLELQIASLNNEIERLEARLERLEdrrERLQQEIEELLKKLEEAELKELQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   564 LSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEgEGIAPIKMKVFLEDTGQDFPlmpneESSLPAVEKE 643
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLEGFS-----EGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   644 QASTEHQSRTSEEISLnDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKsqilelELNFHKAQEIYEKNLDEKAKEI 723
Cdd:TIGR02168  516 SGLSGILGVLSELISV-DEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLK------QNELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   724 SNLNQL--IEEFKKNADNNSSAFTALSEERDQLLSQVKelsMVTelraqvkqlemNLAEAERQRRLDYESQtahdNLLTE 801
Cdd:TIGR02168  589 NDREILknIEGFLGVAKDLVKFDPKLRKALSYLLGGVL---VVD-----------DLDNALELAKKLRPGY----RIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   802 QIHSLSIE------AKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVlegaervrhisskvEELSQALSQ 875
Cdd:TIGR02168  651 DGDLVRPGgvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL--------------EELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   876 KELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQlnllsraeEAKKEQVE 955
Cdd:TIGR02168  717 LRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA--------EAEIEELE 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   956 EDNEVSSGLKQNYDEMSpagqiskEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLkdesKKEIPLS 1035
Cdd:TIGR02168  789 AQIEQLKEELKALREAL-------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL----SEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1036 ETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL---VKQMNQTLQDKTNQ 1112
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELrekLAQLELRLEGLEVR 937

                          810       820       830
                   ....*....|....*....|....*....|
gi 374532817  1113 IDLLQAEISENQAIIQKLITSNTDASDGDS 1142
Cdd:TIGR02168  938 IDNLQERLSEEYSLTLEEAEALENKIEDDE 967
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 151-1020 9.37e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 9.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   151 HKLQEKEELISTLQAQLTQAQAEQpAQSSTEMEEFVmmkQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREKDAR 230
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEEL-EKLTEEISELE---KRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIAS 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   231 FETQVRLHEDELLQLVTQadvETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNT 310
Cdd:TIGR02169  306 LERSIAEKERELEDAEER---LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   311 LRNTVETEREESKILLEKMElevaerklsfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQ 390
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREIN-----------ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIK 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   391 KTGQELQSACDALKDQNSKLLQDKNEqavqsaqtIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAV 470
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEE--------YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGV 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   471 ---TEENIASLQKRVVELENEKGAlllssiELEELKAENEKLSSQITLLEAQNRTGEAdrevSEISIVDIANKRSSSAEE 547
Cdd:TIGR02169  524 hgtVAQLGSVGERYATAIEVAAGN------RLNNVVVEDDAVAKEAIELLKRRKAGRA----TFLPLNKMRDERRDLSIL 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   548 SGQDVLEntfsqkhkeLSVLLLEMKEAQEEIAFLKLQLQG-KRAEEADHEVLDQKEMKQMEGEgiapikmkvFLEDTGqd 626
Cdd:TIGR02169  594 SEDGVIG---------FAVDLVEFDPKYEPAFKYVFGDTLvVEDIEAARRLMGKYRMVTLEGE---------LFEKSG-- 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   627 fpLMPNEESSLPAVEKEQASTEHQSRtseeislndagvELKSTKQDGDKSLSAVpdigqchQDELERLKSQILELELNFH 706
Cdd:TIGR02169  654 --AMTGGSRAPRGGILFSRSEPAELQ------------RLRERLEGLKRELSSL-------QSELRRIENRLDELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   707 KAqeiyEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEMNLAEAERQR 785
Cdd:TIGR02169  713 DA----SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELeARIEELEEDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   786 RLDYESQtahdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSK 865
Cdd:TIGR02169  789 SHSRIPE------IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGK 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   866 VEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEekfsLGVEIKTLKEQLNLLSR 945
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSE----LKAKLEALEEELSEIED 938

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 374532817   946 AEEAKKEQVEED---NEVSSGLKQNYDEMSPAGQISKEELQhEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE 1020
Cdd:TIGR02169  939 PKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNMLAIQ-EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1421-2914 1.18e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.06  E-value: 1.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1421 SEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAAL--ISRK 1498
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELE----EENEDSIHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIknISDK 615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1499 -EALKENKSLQEELSLARGTIERLTK-SLADVESQVSAQNKEKDTVLGRLA-LLQEERDKLITEMDRSLLENQSLSssce 1575
Cdd:TIGR01612  616 nEYIKKAIDLKKIIENNNAYIDELAKiSPYQVPEHLKNKDKIYSTIKSELSkIYEDDIDALYNELSSIVKENAIDN---- 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1576 slklaleglTEDKEKLvkeiESLKSSKIAESTEWQEKHKELQKEYeilLQSYENVSNEAERIqhVVEAVRQEKQELYGKL 1655
Cdd:TIGR01612  692 ---------TEDKAKL----DDLKSKIDKEYDKIQNMETATVELH---LSNIENKKNELLDI--IVEIKKHIHGEINKDL 753

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1656 RSTEANKKETEKQLQEAEQEMEEMKEKMRKFakskQQKILELEEE-NDRLR------AEVHPAGDTAKECMETLLSSNAS 1728
Cdd:TIGR01612  754 NKILEDFKNKEKELSNKINDYAKEKDELNKY----KSKISEIKNHyNDQINidnikdEDAKQNYDKSKEYIKTISIKEDE 829

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1729 MKEELERVK-MEYETLSK-----KFQSLMSEK-DSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIpge 1801
Cdd:TIGR01612  830 IFKIINEMKfMKDDFLNKvdkfiNFENNCKEKiDSEHEQFAELTNKIKAEISDDKLNDYEKKFNDSKSLINEINKSI--- 906

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1802 teEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQ-IDQLKEriAGLEEEKQKNKeFSQTLENEKNTL-- 1878
Cdd:TIGR01612  907 --EEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKnIDTIKE--SNLIEKSYKDK-FDNTLIDKINELdk 981

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1879 ------LSQISTKDGEL----KMLQEEV--TKMNLLNQQIQEELSRVTKLketaEEEKDDLEERLMNQLAELNGSIGNYC 1946
Cdd:TIGR01612  982 afkdasLNDYEAKNNELikyfNDLKANLgkNKENMLYHQFDEKEKATNDI----EQKIEDANKNIPNIEIAIHTSIYNII 1057

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1947 QDVTDAQIKN-ELLESE-MKNLKKCVSELEEEKQQL----VKEKTKVESEIRKEYLEKIQGAQKEPGNK--SHAKELQEL 2018
Cdd:TIGR01612 1058 DEIEKEIGKNiELLNKEiLEEAEINITNFNEIKEKLkhynFDDFGKEENIKYADEINKIKDDIKNLDQKidHHIKALEEI 1137

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2019 LKEKQQEVKQLQKdciryqeKISALERTVKALefVQTESQKDLEITKENLAQAVEHRKKAQAELasfKVLLddtqSEAAR 2098
Cdd:TIGR01612 1138 KKKSENYIDEIKA-------QINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEI---KKLL----NEIAE 1201

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2099 VLADNLKLKK----ELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV--T 2170
Cdd:TIGR01612 1202 IEKDKTSLEEvkgiNLSYGKNLGKLFLEKIDEEKKKseHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETfnI 1281

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2171 LNKKDKEVQQLQENLDSTVTQLAafTKSMSSLQDD-RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLkdqlrqms 2249
Cdd:TIGR01612 1282 SHDDDKDHHIISKKHDENISDIR--EKSLKIIEDFsEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANI-------- 1351

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2250 ihmeelkINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyhSSQNELAKLESELKSLKDQLtdl 2329
Cdd:TIGR01612 1352 -------YNILKLNKIKKIID-------------------EVKEYTKEIEENNK---NIKDELDKSEKLIKKIKDDI--- 1399

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2330 snSLEKCKEQkgnLEGIIRQQEAD--IQNSKFSYEQL---ETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAI 2404
Cdd:TIGR01612 1400 --NLEECKSK---IESTLDDKDIDecIKKIKELKNHIlseESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKK 1474

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2405 AELRQQHDKEIKELENLLSQEEEENIVLEEeNKKAVDKTNQLMETLKTIKKENIQQKAQLdSFVKSMSSLQNDRDRIVgd 2484
Cdd:TIGR01612 1475 DNATNDHDFNINELKEHIDKSKGCKDEADK-NAKAIEKNKELFEQYKKDVTELLNKYSAL-AIKNKFAKTKKDSEIII-- 1550

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2485 yQQLEERHLSIILE------------KDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDaeliQYREDLNQVITI 2551
Cdd:TIGR01612 1551 -KEIKDAHKKFILEaekseqkikeikKEKFrIEDDAAKNDKSNKAAIDIQLSLENFENKFLKIS----DIKKKINDCLKE 1625

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2552 KDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEdlRRSFNALQEEKQDLSKEIESLKVSISQLTRQVtalqEE 2629
Cdd:TIGR01612 1626 TESIEKKIssFSIDSQDTELKENGDNLNSLQEFLESLKDQ--KKNIEDKKKELDELDSEIEKIEIDVDQHKKNY----EI 1699

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2630 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEER 2709
Cdd:TIGR01612 1700 GIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSKE 1779

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2710 ---VAELARDLVEMEQKLLMVTKENKGLTA-----QIQSFGRSMSSLQNSRDHAN----EELDELKRKYDASLKELAQLK 2777
Cdd:TIGR01612 1780 pitYDEIKNTRINAQNEFLKIIEIEKKSKSylddiEAKEFDRIINHFKKKLDHVNdkftKEYSKINEGFDDISKSIENVK 1859

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2778 EQ-------GLLNRERDAL---------------------LSETAFSMNSTEENS--LSHLEKLNQQLLSkdeqllHLSS 2827
Cdd:TIGR01612 1860 NStdenllfDILNKTKDAYagiigkkyysykdeaekifinISKLANSINIQIQNNsgIDLFDNINIAILS------SLDS 1933

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2828 QLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSA---------AQPSTSPAEVQSLKKAMSSLQNDRDRL 2898
Cdd:TIGR01612 1934 EKEDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQdtlniifenQQLYEKIQASNELKDTLSDLKYKKEKI 2013

                         1610
                   ....*....|....*.
gi 374532817  2899 LKELKNLQQQYLQINQ 2914
Cdd:TIGR01612 2014 LNDVKLLLHKFDELNK 2029
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1313-1923 1.21e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 1.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1313 KAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHL 1392
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1393 RELQPKLDELQKLISKKeedVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1472
Cdd:TIGR04523  203 LSNLKKKIQKNKSLESQ---ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1473 PEEIGEESRAKQQIQRKLQAAlisrkealkENKSLQEELSLARGTIERLTKSLADVESQVSAQNKekdtvlgRLALLQEE 1552
Cdd:TIGR04523  280 NKKIKELEKQLNQLKSEISDL---------NNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNK-------IISQLNEQ 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1553 RDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKiaestewqekhkelqKEYEILLQSYENVSN 1632
Cdd:TIGR04523  344 ISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQI---------------NDLESKIQNQEKLNQ 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1633 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKIleleeendrlraevhpag 1712
Cdd:TIGR04523  409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL------------------ 470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1713 dtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTnvte 1792
Cdd:TIGR04523  471 -------KVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESK---- 539

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1793 egTQSIPGETEEQDSlsmstrptcsesvpsaksanpaVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLE 1872
Cdd:TIGR04523  540 --ISDLEDELNKDDF----------------------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKE 595

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 374532817  1873 NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEE 1923
Cdd:TIGR04523  596 KEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQE 646
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1311-2158 1.21e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 1.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1311 QIKAQLKEIEAEKvELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLES----SQLQI 1386
Cdd:TIGR00606  225 QITSKEAQLESSR-EIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1387 AGLEH-----LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTK-------IQTEIIEQEDLIKALHTQLEMQAKE 1454
Cdd:TIGR00606  304 NDLYHnhqrtVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRlqlqadrHQEHIRARDSLIQSLATRLELDGFE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1455 HDERIKQLQVELCEMKQKPEEigEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLARGTIERLTKSLADVESQvsa 1534
Cdd:TIGR00606  384 RGPFSERQIKNFHTLVIERQE--DEAKTAAQLCADLQSKERLKQEQADE---IRDEKKGLGRTIELKKEILEKKQEE--- 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1535 qnkekdtvlgrLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALE-GLTEDKEKLVKEIESLKSSKIAESTEWQEKH 1613
Cdd:TIGR00606  456 -----------LKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKnSLTETLKKEVKSLQNEKADLDRKLRKLDQEM 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1614 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLrSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQk 1693
Cdd:TIGR00606  525 EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLL-GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELAS- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1694 ileLEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEE--LERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGN 1771
Cdd:TIGR00606  603 ---LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEEsdLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSC 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1772 VSKQANLEATEKHDNQ-TNVTEEGTQSIPGETEEQDSLSMSTRptcsesvpsaKSANPAVSKDFSSHDEINNYLQQIDQL 1850
Cdd:TIGR00606  680 CPVCQRVFQTEAELQEfISDLQSKLRLAPDKLKSTESELKKKE----------KRRDEMLGLAPGRQSIIDLKEKEIPEL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1851 KERIAGLEEEKQKNKEFSQtlenEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE--------- 1921
Cdd:TIGR00606  750 RNKLQKVNRDIQRLKNDIE----EQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQgsdldrtvq 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1922 ------EEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1995
Cdd:TIGR00606  826 qvnqekQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIK 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1996 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKEN-------- 2067
Cdd:TIGR00606  906 DAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETelntvnaq 985

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2068 LAQAVEHRKKAQAELASFKVLLdDTQSEAARVLADNLKLKK---ELQSNKESVKSQMKQKDEDLERRLEQAEEKhlkekk 2144
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQDI-DTQKIQERWLQDNLTLRKrenELKEVEEELKQHLKEMGQMQVLQMKQEHQK------ 1058

                          890
                   ....*....|....
gi 374532817  2145 nMQEKLDALRREKV 2158
Cdd:TIGR00606 1059 -LEENIDLIKRNHV 1071
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1300-1536 2.71e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 2.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1300 ASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKL 1379
Cdd:COG4942    13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1380 ESSQLQIAGLEHlrELQPKLDELQKLISKKEEDV---SYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHD 1456
Cdd:COG4942    93 AELRAELEAQKE--ELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1457 ERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELslaRGTIERLTKSLADVESQVSAQN 1536
Cdd:COG4942   171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL---EALIARLEAEAAAAAERTPAAG 247
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1384-1659 3.34e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 53.01  E-value: 3.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1384 LQIAGLEhlRELQPKLDELQKL-----ISKKEED----VSYLSGQLSEKEAALTKIQTeIIEQEDLIKALhtQLEMQAKE 1454
Cdd:PRK05771    9 VLIVTLK--SYKDEVLEALHELgvvhiEDLKEELsnerLRKLRSLLTKLSEALDKLRS-YLPKLNPLREE--KKKVSVKS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1455 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQaaliSRKEALKENKSLQEELSLAR---------GTI-----ER 1520
Cdd:PRK05771   84 LEELIKDVEEELEKIEKEIKELEEEISELENEIKELE----QEIERLEPWGNFDLDLSLLLgfkyvsvfvGTVpedklEE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1521 LTKSLADVESQVSAQNKEKDTVLgrLALLQEERDKLITEMDRSLLENQSLSSScESLKLALEGLTEDKEKLVKEIESLKs 1600
Cdd:PRK05771  160 LKLESDVENVEYISTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESLL- 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 374532817 1601 SKIAESTEwqekhkelqKEYEILLQSYENVSNEAERiqhvveavrqekQELYGKLRSTE 1659
Cdd:PRK05771  236 EELKELAK---------KYLEELLALYEYLEIELER------------AEALSKFLKTD 273
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2356-3014 3.55e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 3.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2356 NSKFSYEQLETDLQaSRELTSRLHEEINMKEQKiisllsgkeEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEE 2435
Cdd:TIGR02169  208 EKAERYQALLKEKR-EYEGYELLKEKEALERQK---------EAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2436 NKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2515
Cdd:TIGR02169  278 NKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2516 EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEAnEDLRRSF 2595
Cdd:TIGR02169  358 EYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI-AGIEAKI 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2596 NALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-----GTLGLYHAQLKVKEEEVHRLSALFSSSQKR----------- 2659
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQElydlkEEYDRVEKELSKLQRELAEAEAQARASEERvrggraveevl 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2660 ----------IAEL------------------------EEELV---CVQKEAAKKVG----------------------- 2679
Cdd:TIGR02169  517 kasiqgvhgtVAQLgsvgeryataievaagnrlnnvvvEDDAVakeAIELLKRRKAGratflplnkmrderrdlsilsed 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2680 ----------EIEDKLKKELKHLHHDAGIMRNeTETAEE-----RVAELARDLVE----------MEQKLLMVTKENKG- 2733
Cdd:TIGR02169  597 gvigfavdlvEFDPKYEPAFKYVFGDTLVVED-IEAARRlmgkyRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAe 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2734 ---LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQL-KEQGLLNRERDALLSETafsmnsteENSLSHLE 2809
Cdd:TIGR02169  676 lqrLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERL--------EELEEDLS 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2810 KLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHlwnelEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMS 2889
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-----SRIPEIQAELSKLEEEVSRIEARLREIEQKLN 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2890 SLQNDRDRLLKELKNLQQQYL----QINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWE 2965
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIdlkeQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELE 902

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2966 IHERRMKEQY----------LMAISDKDQQLSHLQNLIRELRSSSSQTQPL-KVQYQRQA 3014
Cdd:TIGR02169  903 RKIEELEAQIekkrkrlselKAKLEALEEELSEIEDPKGEDEEIPEEELSLeDVQAELQR 962
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1332-2263 3.61e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.13  E-value: 3.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1332 STTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEE 1411
Cdd:TIGR00606  166 SEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYEN 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1412 DVSYLSGQLSEKEAALTKIQteiiEQEDLIKALH-TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKL 1490
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIM----KLDNEIKALKsRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKEREL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1491 QAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLIT------------ 1558
Cdd:TIGR00606  322 VDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErqiknfhtlvie 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1559 -EMDRSLLENQSLSSSCESLKLALEGLTE--------------DKEKLVKEIESLKSSK------IAESTEWQEKHKELQ 1617
Cdd:TIGR00606  402 rQEDEAKTAAQLCADLQSKERLKQEQADEirdekkglgrtielKKEILEKKQEELKFVIkelqqlEGSSDRILELDQELR 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1618 KEYEILLQSYENVSNEAERIQhvVEAVRQEKQELYGKLRSTEanKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILEL 1697
Cdd:TIGR00606  482 KAERELSKAEKNSLTETLKKE--VKSLQNEKADLDRKLRKLD--QEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSR 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1698 EEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1777
Cdd:TIGR00606  558 HSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1778 LEATEKHDNQTNVTEEGTQSIPGETEEQDSLsmstrptCSESVPSAKSANPAVSKDFSSHDEINNYlqqIDQLKERIAGL 1857
Cdd:TIGR00606  638 ESDLERLKEEIEKSSKQRAMLAGATAVYSQF-------ITQLTDENQSCCPVCQRVFQTEAELQEF---ISDLQSKLRLA 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1858 EEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDL--EERLMNQL 1935
Cdd:TIGR00606  708 PDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpEEESAKVC 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1936 AELNGSIGNYCQDVTDAQIKNELLESEMK--NLKKCVSELEEEKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPG 2007
Cdd:TIGR00606  788 LTDVTIMERFQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIElnrkliQDQQEQIQHLKSKTN 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2008 N-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAElasfk 2086
Cdd:TIGR00606  868 ElKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK----- 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2087 vlLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALrrEKVHLEETIGE 2166
Cdd:TIGR00606  943 --VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI--DTQKIQERWLQ 1018

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2167 IQVTLNKKDKEVQQLQENLDSTVTQLAAF-TKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEI-----RLKEDNCSV 2240
Cdd:TIGR00606 1019 DNLTLRKRENELKEVEEELKQHLKEMGQMqVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIkhfkkELREPQFRD 1098

                          970       980
                   ....*....|....*....|...
gi 374532817  2241 LKDQLRQMSIHMEELKINISRLE 2263
Cdd:TIGR00606 1099 AEEKYREMMIVMRTTELVNKDLD 1121
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
208-384 3.88e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 3.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  208 QTQAEQAAQLssmqQVVREKDARFEtQVRLHEDELLQLVTQADVETEmQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 287
Cdd:COG4913   245 EDAREQIELL----EPIRELAERYA-AARERLAELEYLRAALRLWFA-QRRLELLEAELEELRAELARLEAELERLEARL 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  288 TAAEQ-----RNQILS---QQLQQMEAEHNTL---RNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQ 356
Cdd:COG4913   319 DALREeldelEAQIRGnggDRLEQLEREIERLereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEE 398

                         170       180       190
                  ....*....|....*....|....*....|..
gi 374532817  357 ----AGQAQAELESRYSALEQKHKAEMEEKTS 384
Cdd:COG4913   399 eleaLEEALAEAEAALRDLRRELRELEAEIAS 430
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 35-621 5.18e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 5.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817    35 HQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEM 114
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   115 KAQG--------------------------------GTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHK-LQEKEELIS 161
Cdd:pfam15921  155 EAAKclkedmledsntqieqlrkmmlshegvlqeirSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKiLRELDTEIS 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   162 TLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEK-EEFISTLQAQLS------QTQAEQAAQLSSMQQVVREKDARFETQ 234
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRiEQLISEHEVEITgltekaSSARSQANSIQSQLEIIQEQARNQNSM 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   235 VRLHEDELLQLVTQadVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 314
Cdd:pfam15921  315 YMRQLSDLESTVSQ--LRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   315 VETEREESKILLEK-----MELEVAERKLSFHNLQ-EEMHHLLEQFEQagQAQAELESRYSALEQKHKAeMEEKTSHILS 388
Cdd:pfam15921  393 LSLEKEQNKRLWDRdtgnsITIDHLRRELDDRNMEvQRLEALLKAMKS--ECQGQMERQMAAIQGKNES-LEKVSSLTAQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   389 LQKTGQELQSACDALKDQnsKLLQDKNEQAVQS-AQTIQQLEDQLQQKSKEISQFLNRLPLQ----QHETASQTSFPDVY 463
Cdd:pfam15921  470 LESTKEMLRKVVEELTAK--KMTLESSERTVSDlTASLQEKERAIEATNAEITKLRSRVDLKlqelQHLKNEGDHLRNVQ 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   464 NE---------GTQAVTE---ENIASLQKRVVELENEKGALLLSS-----------IELEELKAENEKLSSQITLLEAQn 520
Cdd:pfam15921  548 TEcealklqmaEKDKVIEilrQQIENMTQLVGQHGRTAGAMQVEKaqlekeindrrLELQEFKILKDKKDAKIRELEAR- 626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   521 rtgEADREVSEISIVDIANKRSSSAEESGQ--DVLENTFSQKHKELSVLLLEM---------KEAQEEIAFLKLQLQGKR 589
Cdd:pfam15921  627 ---VSDLELEKVKLVNAGSERLRAVKDIKQerDQLLNEVKTSRNELNSLSEDYevlkrnfrnKSEEMETTTNKLKMQLKS 703

                          650       660       670
                   ....*....|....*....|....*....|..
gi 374532817   590 AEEADHEVldQKEMKQMEGEGIAPIKMKVFLE 621
Cdd:pfam15921  704 AQSELEQT--RNTLKSMEGSDGHAMKVAMGMQ 733
PTZ00121 PTZ00121
MAEBL; Provisional
 945-1649 6.41e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 6.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  945 RAEEAKK-EQVEEDNEVSSGLK-------QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 1016
Cdd:PTZ00121 1177 KAEAARKaEEVRKAEELRKAEDarkaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK 1256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1017 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE-QF 1095
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAaKK 1336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1096 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNtDASDGDSVALVKETVVISPPCTGSSEHWKPELEE--KILA 1173
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE-AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElkKAAA 1415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1174 LEKEKEQLQKKLQEAltsRKAILKKAQEKERHLREELKQQKDDYNRLQEQfdEQSKENENIGDQLRQLQIQVRESIDGKL 1253
Cdd:PTZ00121 1416 AKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEA--KKKAEEAKKADEAKKKAEEAKKADEAKK 1490

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1254 PSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESnlcpDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVElelkvsst 1333
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELK-------- 1558

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1334 TSELTKKSEEVFQLQEQINKQGLEIESLKTVshEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELqklisKKEEDV 1413
Cdd:PTZ00121 1559 KAEEKKKAEEAKKAEEDKNMALRKAEEAKKA--EEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL-----KKAEEE 1631

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1414 SYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQ--RKLQ 1491
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEelKKKE 1711

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1492 AALISRKEALK------------------ENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRlaLLQEER 1553
Cdd:PTZ00121 1712 AEEKKKAEELKkaeeenkikaeeakkeaeEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE--ELDEED 1789

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1554 DKLITEMDRSLLENQSLSSSCES----LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYEN 1629
Cdd:PTZ00121 1790 EKRRMEVDKKIKDIFDNFANIIEggkeGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869

                         730       740
                  ....*....|....*....|
gi 374532817 1630 VSNEAERIQHVVEAVRQEKQ 1649
Cdd:PTZ00121 1870 FNKEKDLKEDDEEEIEEADE 1889
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2501-2909 7.57e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 7.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2501 QLIQEAAAENNKLKEEIRGLrshmDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELEnkyakleek 2580
Cdd:TIGR02169  146 DFISMSPVERRKIIDEIAGV----AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--------- 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2581 lkeseeanedlrrsFNALQEEKQD-----LSKEIESLKVSISQLTRQVTALqeegtlglyhaqlkvkEEEVHRLSALFSS 2655
Cdd:TIGR02169  213 --------------YQALLKEKREyegyeLLKEKEALERQKEAIERQLASL----------------EEELEKLTEEISE 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2656 SQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHhdagimrNETETAEERVAELARDLVEMEQKLLMVTKENKGLT 2735
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELE-------AEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2736 AQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAfsmnsteENSLSHLEKLNQQL 2815
Cdd:TIGR02169  336 AEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL-------EKLKREINELKREL 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2816 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKfrksEEGKQRSAAqpstspAEVQSLKKAMSSLQNDR 2895
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK----QEWKLEQLA------ADLSKYEQELYDLKEEY 478

                          410
                   ....*....|....
gi 374532817  2896 DRLLKELKNLQQQY 2909
Cdd:TIGR02169  479 DRVEKELSKLQREL 492
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1395-1940 8.30e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 8.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1395 LQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQT--EIIEQ----------------EDLIKALHTQLEMQAKEHD 1456
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSqlEIIQEqarnqnsmymrqlsdlESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1457 ERIKQLQ-------VELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL----KENKSLQEELSLARGTIERLTKSL 1525
Cdd:pfam15921  342 DKIEELEkqlvlanSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELslekEQNKRLWDRDTGNSITIDHLRREL 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1526 ADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAE 1605
Cdd:pfam15921  422 DDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDL 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1606 STEWQEKHK----------ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ---EA 1672
Cdd:pfam15921  502 TASLQEKERaieatnaeitKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQH 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1673 EQEMEEMKEKMRKFAKSKQQKILELEE-------ENDRLRAEVHPAGDTAKECMEtLLSSNASMKEELERVKMEYETLSK 1745
Cdd:pfam15921  582 GRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkKDAKIRELEARVSDLELEKVK-LVNAGSERLRAVKDIKQERDQLLN 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1746 KFQSLMSEKDSLSEEVQDLKHQIEGNvskqanleaTEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKS 1825
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLKRNFRNK---------SEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMG 731

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1826 ANPAVSKDFSSHDEINNYLQQIDQL-----KERiAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMN 1900
Cdd:pfam15921  732 MQKQITAKRGQIDALQSKIQFLEEAmtnanKEK-HFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 374532817  1901 LLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNG 1940
Cdd:pfam15921  811 VALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2115-2797 9.11e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 9.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2115 ESVKSQMKQKDEDLERRLEQAEEKHLKEK--------------KNMQEKLDAL----RREKVHLEETIGEIQVTLNKKDK 2176
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKfylrqsvidlqtklQEMQMERDAMadirRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2177 EVQQLQENLDSTVTQLAAFTKSMSS----LQDDRDRVIDEAKKWERKFSDAIQSKEEEIRlkeDNCSVLKDQLRQMSIHM 2252
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLShegvLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---SLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2253 EELKINISRLEHDKQIWESKAQTEVQL----QQKVCDTLQGENKELLSQLEETRHlyhSSQNELAKLESELKSLKDQLTD 2328
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNKIELllqqHQDRIEQLISEHEVEITGLTEKAS---SARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2329 lSNSLEKCkeQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ-----ASRELTSRLHEEINMKE---------QKIISLLS 2394
Cdd:pfam15921  311 -QNSMYMR--QLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlANSELTEARTERDQFSQesgnlddqlQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2395 GKEEAIQ-----------------VAIAELRQQHDK---EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIK 2454
Cdd:pfam15921  388 KREKELSlekeqnkrlwdrdtgnsITIDHLRRELDDrnmEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLT 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2455 KENIQQKAQLDSFVKSMSSLQ---NDRDRIVGDYQqleerhlSIILEKDQLIQEAAAENNKLK-------EEIRGLRSHM 2524
Cdd:pfam15921  468 AQLESTKEMLRKVVEELTAKKmtlESSERTVSDLT-------ASLQEKERAIEATNAEITKLRsrvdlklQELQHLKNEG 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2525 DDLNSENAKLDAELIQYREDlNQVITIKDSQQKQLLEVQLQQNKELenkyAKLEEKLKESEEANEDLRRSFNALQEEKQD 2604
Cdd:pfam15921  541 DHLRNVQTECEALKLQMAEK-DKVIEILRQQIENMTQLVGQHGRTA----GAMQVEKAQLEKEINDRRLELQEFKILKDK 615

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2605 LSKEIESLKVSISQLTRQVTALQEEGTLGLyHAQLKVKEEEVHRLSALfSSSQKRIAELEEELVCVQKEAAKKVGEIE-- 2682
Cdd:pfam15921  616 KDAKIRELEARVSDLELEKVKLVNAGSERL-RAVKDIKQERDQLLNEV-KTSRNELNSLSEDYEVLKRNFRNKSEEMEtt 693

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2683 -DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2761
Cdd:pfam15921  694 tNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNK 773

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 374532817  2762 LKRKYDASLKELAQLKEQGLLNRERDALLSETAFSM 2797
Cdd:pfam15921  774 LSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809
PRK11281 PRK11281
mechanosensitive channel MscK;
151-513 9.40e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.84  E-value: 9.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  151 HKLQEKEEliSTLQAQLTQAQA--EQPAQSSTEMEEfvmMKQQLQEkeefistLQAQLSQTQAEQAAQLSSMQQVVREkd 228
Cdd:PRK11281   51 QKLLEAED--KLVQQDLEQTLAllDKIDRQKEETEQ---LKQQLAQ-------APAKLRQAQAELEALKDDNDEETRE-- 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  229 aRFETqvrLHEDELLQLVTQadVETEMQQklrvLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEH 308
Cdd:PRK11281  117 -TLST---LSLRQLESRLAQ--TLDQLQN----AQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGG 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  309 NTLRNTVETERE------ESKILLEKMELEVAERKLSFHNLQeemHHLLEqfEQAGQAQAELESRYSALEQKHKAEMEek 382
Cdd:PRK11281  187 KALRPSQRVLLQaeqallNAQNDLQRKSLEGNTQLQDLLQKQ---RDYLT--ARIQRLEHQLQLLQEAINSKRLTLSE-- 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  383 tshilslqKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQT-IQQLE--DQLQQKSKEISQFLNRlpLQQhetasqtsf 459
Cdd:PRK11281  260 --------KTVQEAQSQDEAARIQANPLVAQELEINLQLSQRlLKATEklNTLTQQNLRVKNWLDR--LTQ--------- 320

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 374532817  460 pdvynegTQAVTEENIASLQkrvvelenekGALLLSSIELEELKA-----ENEKLSSQI 513
Cdd:PRK11281  321 -------SERNIKEQISVLK----------GSLLLSRILYQQQQAlpsadLIEGLADRI 362
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 242-458 1.14e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  242 LLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLR---NTVETE 318
Cdd:COG4942    12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAELEKE 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  319 REESKILLEKMELEVAE--RKLSFHNLQEEMHHLL-----EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQK 391
Cdd:COG4942    92 IAELRAELEAQKEELAEllRALYRLGRQPPLALLLspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 374532817  392 TGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLE------DQLQQKSKEISQFLNRLPLQQHETASQTS 458
Cdd:COG4942   172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAelaaelAELQQEAEELEALIARLEAEAAAAAERTP 244
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1307-1465 1.16e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1307 TSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLktvsheaevhaESLQQKLESSQLQI 1386
Cdd:COG1579    17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEV-----------EARIKKYEEQLGNV 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 374532817 1387 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1465
Cdd:COG1579    86 RNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2298-3062 1.22e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 1.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2298 LEETRHLYHSSQ---NELAKLESELK-SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2373
Cdd:pfam15921   80 LEEYSHQVKDLQrrlNESNELHEKQKfYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKC 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2374 LTSRLHEEINMKEQKIISLLSGKE---EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETl 2450
Cdd:pfam15921  160 LKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG- 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2451 KTIKKENIQQKAQLDSFVKSMSSLQNDRDRIvgdyQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNS- 2529
Cdd:pfam15921  239 RIFPVEDQLEALKSESQNKIELLLQQHQDRI----EQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSm 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2530 ---ENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2606
Cdd:pfam15921  315 ymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELS 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2607 KEIESLKVSISQLTRQVTalqeegTLGLYHAQLKVKEEEVHRLSALFSSSQKRI-AELEEELVCVQ--KEAAKKVGEIED 2683
Cdd:pfam15921  395 LEKEQNKRLWDRDTGNSI------TIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQgkNESLEKVSSLTA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2684 KLkkelkhlhhdagimrnetETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSlqnsrdhANEELDELK 2763
Cdd:pfam15921  469 QL------------------ESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEA-------TNAEITKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2764 RKYDASLKELAQLKEQGllnrerDALlsetafsmnsteENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAM 2843
Cdd:pfam15921  524 SRVDLKLQELQHLKNEG------DHL------------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTA 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2844 ASLQNERDHLWNELE---------KFRKSEEGKQRSAAQPSTSPAEVQSLK---------KAMSSLQNDRDRLLKELKNL 2905
Cdd:pfam15921  586 GAMQVEKAQLEKEINdrrlelqefKILKDKKDAKIRELEARVSDLELEKVKlvnagserlRAVKDIKQERDQLLNEVKTS 665

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2906 QQQYLQINQEITELHplkaqlQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWE---IHERRMKEQYLMAISDK 2982
Cdd:pfam15921  666 RNELNSLSEDYEVLK------RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdGHAMKVAMGMQKQITAK 739

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2983 DQQLSHLQNLIR---ELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSN 3059
Cdd:pfam15921  740 RGQIDALQSKIQfleEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQ 819


                   ...
gi 374532817  3060 FSQ 3062
Cdd:pfam15921  820 FAE 822
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2396-3105 1.23e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2396 KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDsfvKSMSSLQ 2475
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELE---KLTEEIS 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2476 NDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQ 2555
Cdd:TIGR02169  262 ELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2556 QKQLLEVQLQQNK------ELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLtrQVTALQEE 2629
Cdd:TIGR02169  342 EREIEEERKRRDKlteeyaELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL--QEELQRLS 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2630 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqKEAAKKVGEIEDKLKKelkhlhhdagiMRNETETAEER 2709
Cdd:TIGR02169  420 EELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL----EQLAADLSKYEQELYD-----------LKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2710 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRdhanEELDELKRKYDASLkELAQLKEQGLLNRERDAL 2789
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTV----AQLGSVGERYATAI-EVAAGNRLNNVVVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2790 LSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQV---QSFSKA----------MASLQNERDHLWN- 2855
Cdd:TIGR02169  560 AKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVefdPKYEPAfkyvfgdtlvVEDIEAARRLMGKy 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2856 -----ELEKFRKS------EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH---- 2920
Cdd:TIGR02169  640 rmvtlEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASrkig 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2921 PLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLR--MEKSSWEIHERRMK-EQYLMAISDKDQQLSH--------- 2988
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKseLKELEARIEELEEDlHKLEEALNDLEARLSHsripeiqae 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2989 LQNLIRELRSSSSQTQPLKVQYQRQASPETSASpDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKN 3068
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE-KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 374532817  3069 TLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQEL 3105
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
707-912 1.29e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.17  E-value: 1.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  707 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADnnssaFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEMNLAEAERQr 785
Cdd:COG3206   175 KALEFLEEQLPELRKELEEAEAALEEFRQKNG-----LVDLSEEAKLLLQQLSELeSQLAEARAELAEAEARLAALRAQ- 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  786 rLDYESQTAHDNLLTEQIHSLSIEakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRH---- 861
Cdd:COG3206   249 -LGSGPDALPELLQSPVIQQLRAQ-------LAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAslea 320

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 374532817  862 ----ISSKVEELSQALSQKELEITKMDQL---LLEKKRDVETLQQTIEEKDQQVTEIS 912
Cdd:COG3206   321 eleaLQAREASLQAQLAQLEARLAELPELeaeLRRLEREVEVARELYESLLQRLEEAR 378
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2354-2909 1.88e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 1.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2354 IQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI--ISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQEEEENIV 2431
Cdd:PRK03918  171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLreINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELES 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2432 LEEENKKAVDKTNQLMETLKTIKKEniqqKAQLDSFVKSMSSLQNDRDRivgdYQQLEERHLSIILEKDQLIQEAAaenn 2511
Cdd:PRK03918  250 LEGSKRKLEEKIRELEERIEELKKE----IEELEEKVKELKELKEKAEE----YIKLSEFYEEYLDELREIEKRLS---- 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2512 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK----QLLEVQLQQNKELENKYAKL--EEKLKESE 2585
Cdd:PRK03918  318 RLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeeaKAKKEELERLKKRLTGLTPEklEKELEELE 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2586 EANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT----------RQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSS 2655
Cdd:PRK03918  398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2656 SQKRIAELEEEL-----VCVQKEAAKKVGEIEDKLKK-----------ELKHLHHDAGIMRNETETAE---ERVAELARD 2716
Cdd:PRK03918  478 LRKELRELEKVLkkeseLIKLKELAEQLKELEEKLKKynleelekkaeEYEKLKEKLIKLKGEIKSLKkelEKLEELKKK 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2717 LVEMEQKLLMVTKENKGLTAQIQSFGRSmsslqnSRDHANEELDELKRKYDA--SLKELAQLKEQGLLNRERDALLSETA 2794
Cdd:PRK03918  558 LAELEKKLDELEEELAELLKELEELGFE------SVEELEERLKELEPFYNEylELKDAEKELEREEKELKKLEEELDKA 631

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2795 FSMNSTEENSLSHLEKLNQQLLSKDEQLLHlssqlEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQP 2874
Cdd:PRK03918  632 FEELAETEKRLEELRKELEELEKKYSEEEY-----EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                         570       580       590
                  ....*....|....*....|....*....|....*
gi 374532817 2875 STSPAEVQSLKKAMSSLQNDRDRlLKELKNLQQQY 2909
Cdd:PRK03918  707 EKAKKELEKLEKALERVEELREK-VKKYKALLKER 740
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 998-1875 1.88e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   998 RKLQAALinrkELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE-NKEYSEKCVTSKCQEIEIYLKQT------ 1070
Cdd:TIGR02169  170 RKKEKAL----EELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQKeaierq 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1071 ISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKT-NQIDLLQAEISENQAIIQKLITSNTDASDgdSVALVKET 1149
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGeEEQLRVKEKIGELEAEIASLERSIAEKER--ELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1150 VVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKE---RHLREELKQQKDDYNRLQEQFDE 1226
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDkefAETRDELKDYREKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1227 QSKENENIGDQLRQLQIQVREsIDGKLPSTDQQ--ESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQ 1304
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELAD-LNAAIAGIEAKinELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1305 GGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEE-----VFQLQEQINKQGLEIES-----LKTVSHEAEVHAES 1374
Cdd:TIGR02169  483 KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtVAQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1375 LQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKI---QTEIIEQEDLIKALHTQLEMQ 1451
Cdd:TIGR02169  563 AIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYvfgDTLVVEDIEAARRLMGKYRMV 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1452 AKEHDERIK---------QLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLT 1522
Cdd:TIGR02169  643 TLEGELFEKsgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1523 KSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRsllenqslssscesLKLALEGLTEDKEKLVKEIESLKSSK 1602
Cdd:TIGR02169  723 KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE--------------LEARIEELEEDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1603 IAEstEWQEKHKELQKEYEIlLQSYENVSNEAERI----QHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAeqemee 1678
Cdd:TIGR02169  789 SHS--RIPEIQAELSKLEEE-VSRIEARLREIEQKlnrlTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL------ 859

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1679 mkekmrkfakskQQKILELEEENDRLRAEVhpagdtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLS 1758
Cdd:TIGR02169  860 ------------NGKKEELEEELEELEAAL-----------RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1759 EEVQDLKHQIEGNVSKQANLEATEKHDnqtnvteegtQSIPGETEEQDSLSMsTRPTCSESVPSAKSANpavskdFSSHD 1838
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGED----------EEIPEEELSLEDVQA-ELQRVEEEIRALEPVN------MLAIQ 979

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 374532817  1839 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEK 1875
Cdd:TIGR02169  980 EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1836-2538 1.94e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1836 SHDEINNYLQQIDQlkerIAGLEEEKQKnkefSQTLENEKNTLLSQIStkdgELKMLQEEVTKMNLlnqQIQEELSRVTK 1915
Cdd:pfam12128  219 NRQQVEHWIRDIQA----IAGIMKIRPE----FTKLQQEFNTLESAEL----RLSHLHFGYKSDET---LIASRQEERQE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1916 LKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcvSELEEEKQQLVKEKTkVESEIrkEY 1995
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLPS-WQSEL--EN 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1996 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQL----QKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2071
Cdd:pfam12128  359 LEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIagikDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2072 VEHRKKAQAELasfKVLLDDTQSEaarvladnlklkKELQSNKESVKSQMKQKDEDLERR---LEQAEEKHLKEKKNMQE 2148
Cdd:pfam12128  439 EYRLKSRLGEL---KLRLNQATAT------------PELLLQLENFDERIERAREEQEAAnaeVERLQSELRQARKRRDQ 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2149 KLDALRREKVHLEETIGEIqvtlnkkdkevQQLQENLDSTVTQLAAFTKSMSSL-QDDRDRVIDEAKKWErkfSDAIQSK 2227
Cdd:pfam12128  504 ASEALRQASRRLEERQSAL-----------DELELQLFPQAGTLLHFLRKEAPDwEQSIGKVISPELLHR---TDLDPEV 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2228 EEEIRLKEDNCSVLKDQLRQMSI-----HMEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETR 2302
Cdd:pfam12128  570 WDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKAEEALQ----SAREKQAAAEEQLVQANGELEKASREETFAR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2303 HLYHSSQNELAKLESELKSLKDQLTD-LSNSLEKCKEQKGNLEGIIRQQEADIQNSkfsyeqletdLQASRELTSRLHEE 2381
Cdd:pfam12128  646 TALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSLEAQLKQLDKKHQAW----------LEEQKEQKREARTE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2382 INMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKeNIQQK 2461
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAV-RRQEV 794

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 374532817  2462 AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKdqLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAEL 2538
Cdd:pfam12128  795 LRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLAR--LIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM 869
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1588-2916 2.05e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 50.82  E-value: 2.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1588 KEKLVKEIESLKSSKIAESTEWQEKHKELQKEYE-------ILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTeA 1660
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEeenedsiHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNI-S 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1661 NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRaevhpagdtakecmetllssnASMKEELERV-KME 1739
Cdd:TIGR01612  614 DKNEYIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIY---------------------STIKSELSKIyEDD 672

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1740 YETLSKKFQSLMSEKDSLSEE----VQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPT 1815
Cdd:TIGR01612  673 IDALYNELSSIVKENAIDNTEdkakLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKD 752

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1816 CSESVPSAKSANPAVSKDFSSH----DEINNYLQQIDQLKERIAG-LEEEKQKNKEFSQTLENEKNtLLSQISTKDGELK 1890
Cdd:TIGR01612  753 LNKILEDFKNKEKELSNKINDYakekDELNKYKSKISEIKNHYNDqINIDNIKDEDAKQNYDKSKE-YIKTISIKEDEIF 831

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1891 MLQEEVTKMNllnqqiQEELSRVTKLKETAEEEKDDLEERlMNQLAELNGSIGNycqdvtdaQIKNELLESEMKNLKKCV 1970
Cdd:TIGR01612  832 KIINEMKFMK------DDFLNKVDKFINFENNCKEKIDSE-HEQFAELTNKIKA--------EISDDKLNDYEKKFNDSK 896

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1971 SELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKE--LQELLKEKQQEVKQLQKDCIRYQ--------EKI 2040
Cdd:TIGR01612  897 SLINEINKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQniLKEILNKNIDTIKESNLIEKSYKdkfdntliDKI 976

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2041 SALERTVKALEFVQTESQKDLEIT-----KENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKL--KKELQSN 2113
Cdd:TIGR01612  977 NELDKAFKDASLNDYEAKNNELIKyfndlKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIaiHTSIYNI 1056

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2114 KESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeiqvtlnKKDKEVQQLQENLDSTVTQLA 2193
Cdd:TIGR01612 1057 IDEIEKEIGKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDFGKEENI--------KYADEINKIKDDIKNLDQKID 1128

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2194 AFTKSMSSLQDDRDRVIDEAK----KWERKFSDAIQSKE-EEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQI 2268
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKaqinDLEDVADKAISNDDpEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTS 1208

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2269 WESKAQTEVQLQQKVcdtlqgeNKELLSQLEEtrhlyhssqnELAKLESELKSLKDQLTDLSNSLEKCKEQKgNLEGIIR 2348
Cdd:TIGR01612 1209 LEEVKGINLSYGKNL-------GKLFLEKIDE----------EKKKSEHMIKAMEAYIEDLDEIKEKSPEIE-NEMGIEM 1270

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2349 QQEADIQNSKFSYEQLETDLQASRELTSRLhEEINMKEQKIISLLSGK------EEAIQVAIAElRQQHDKEIKELENLL 2422
Cdd:TIGR01612 1271 DIKAEMETFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEEsdindiKKELQKNLLD-AQKHNSDINLYLNEI 1348

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2423 SQEEEENIVLEEEN--KKAVDKTNQLMETLKTIKKEnIQQKAQLDSFVKSMSSLQNDRDRIVG--DYQQLEERHLSIILE 2498
Cdd:TIGR01612 1349 ANIYNILKLNKIKKiiDEVKEYTKEIEENNKNIKDE-LDKSEKLIKKIKDDINLEECKSKIEStlDDKDIDECIKKIKEL 1427

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2499 KDQLIQEAAAENNKLKEEirglrshmdDLNSENAKLDAELIQYREDLNQ-VITIKDSQQKQLLEV---QLQQNKELENKY 2574
Cdd:TIGR01612 1428 KNHILSEESNIDTYFKNA---------DENNENVLLLFKNIEMADNKSQhILKIKKDNATNDHDFninELKEHIDKSKGC 1498

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2575 AKLEEKLKESEEANEDLRRSFNalQEEKQDLSKEIE-SLKVSISQLTRQVTALQEEgtLGLYHAQLKVKEEevhrlsalf 2653
Cdd:TIGR01612 1499 KDEADKNAKAIEKNKELFEQYK--KDVTELLNKYSAlAIKNKFAKTKKDSEIIIKE--IKDAHKKFILEAE--------- 1565

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2654 sSSQKRIAELEEELVCVQKEAAK-------------KVGEIEDKLKKeLKHLHHDAGIMRNETETAEERVAELARDLVEM 2720
Cdd:TIGR01612 1566 -KSEQKIKEIKKEKFRIEDDAAKndksnkaaidiqlSLENFENKFLK-ISDIKKKINDCLKETESIEKKISSFSIDSQDT 1643

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2721 EqkllmvTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDEL--------------KRKYDASLKElaQLKEQGLLNRER 2786
Cdd:TIGR01612 1644 E------LKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELdseiekieidvdqhKKNYEIGIIE--KIKEIAIANKEE 1715

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2787 dalLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMAS--------------LQNERDH 2852
Cdd:TIGR01612 1716 ---IESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGcletvskepitydeIKNTRIN 1792

                         1370      1380      1390      1400      1410      1420
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 374532817  2853 LWNELEKFRKSEegKQRSAAQPSTSPAEVQSLKKAM-SSLQNDRDRLLKELKNLQQQYLQINQEI 2916
Cdd:TIGR01612 1793 AQNEFLKIIEIE--KKSKSYLDDIEAKEFDRIINHFkKKLDHVNDKFTKEYSKINEGFDDISKSI 1855
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1581-2187 2.21e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 2.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1581 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEIL---LQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1657
Cdd:TIGR04523   98 INKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIdkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNL 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1658 TEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQ------KILELEEENDRLRAEVHPAGD----------TAKECMET 1721
Cdd:TIGR04523  178 LEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKnkslesQISELKKQNNQLKDNIEKKQQeinektteisNTQTQLNQ 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1722 LLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGE 1801
Cdd:TIGR04523  258 LKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKII 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1802 TEEQDSLSmstrptcsesvpsaksanpAVSKDFSSHDEINNYLQ-QIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1880
Cdd:TIGR04523  338 SQLNEQIS-------------------QLKKELTNSESENSEKQrELEEKQNEIEKLKKENQSYKQEIKNLESQINDLES 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1881 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEerlmNQLAELNGSIGNYCQDVTDAQIKNELLE 1960
Cdd:TIGR04523  399 KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT----NQDSVKELIIKNLDNTRESLETQLKVLS 474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1961 SEMKNLKkcvSELEEEKQQLVKEktkvESEIRKEYLEKIQGAQKepgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKI 2040
Cdd:TIGR04523  475 RSINKIK---QNLEQKQKELKSK----EKELKKLNEEKKELEEK-------VKDLTKKISSLKEKIEKLESEKKEKESKI 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2041 SALERTVKALEFvqtesqkdlEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQ 2120
Cdd:TIGR04523  541 SDLEDELNKDDF---------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK 611

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 374532817  2121 MKQKDEDLErRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDS 2187
Cdd:TIGR04523  612 ISSLEKELE-KAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1169-1398 2.77e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1169 EKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1248
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAEL----EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1249 idgklpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTS------VAQIKAQLKEIEAE 1322
Cdd:COG4942    95 ---------LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAparreqAEELRADLAELAAL 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 374532817 1323 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPK 1398
Cdd:COG4942   166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
46 PHA02562
endonuclease subunit; Provisional
 1838-1998 3.14e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 49.63  E-value: 3.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1838 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLK 1917
Cdd:PHA02562  227 EEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCT-QQISEGPDRITKIK 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1918 E---------TAEEEKDDLEERLMNQLA-------ELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLV 1981
Cdd:PHA02562  306 DklkelqhslEKLDTAIDELEEIMDEFNeqskkllELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQ 385

                         170
                  ....*....|....*..
gi 374532817 1982 KEKTKVESEIRKEYLEK 1998
Cdd:PHA02562  386 DELDKIVKTKSELVKEK 402
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2243-2859 3.94e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 3.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2243 DQLRQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHlyHSSQNELAKLESELK 2320
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELE 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2321 SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ-EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEA 2399
Cdd:COG4913   313 RLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF--------AA 384

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2400 IQVAIAELRQQHDKEIKELENLLSQEEEENivleeenKKAVDKTNQLMETLKTIKkeniQQKAQLDSFVKSM-----SSL 2474
Cdd:COG4913   385 LRAEAAALLEALEEELEALEEALAEAEAAL-------RDLRRELRELEAEIASLE----RRKSNIPARLLALrdalaEAL 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2475 QNDRD--RIVGDYQQLEERH---------------LSIILEKDQLIQEAAA-ENNKLKEEIRGLRSHMDDLNSENAKLDA 2536
Cdd:COG4913   454 GLDEAelPFVGELIEVRPEEerwrgaiervlggfaLTLLVPPEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDP 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2537 EliqyreDLNQVITIKDSQQKQLLEVQLQqnkelenkyakleeklkeseeanedlrRSFNALQEEkqdlskeieslkvSI 2616
Cdd:COG4913   534 D------SLAGKLDFKPHPFRAWLEAELG---------------------------RRFDYVCVD-------------SP 567

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2617 SQLTRQVTALQEEGTL-GLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKkVGEIEDKLKKELKHLH-- 2693
Cdd:COG4913   568 EELRRHPRAITRAGQVkGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAE-AEERLEALEAELDALQer 646

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2694 HDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAqiqsfgrsmssLQNSRDHANEELDELKRKYDASLKEL 2773
Cdd:COG4913   647 REALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA-----------LEEQLEELEAELEELEEELDELKGEI 715

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2774 AQL-KEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLsKDEQLLHLSSQLEDSYnqvqsfskamASLQNERDH 2852
Cdd:COG4913   716 GRLeKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL-GDAVERELRENLEERI----------DALRARLNR 784


                  ....*..
gi 374532817 2853 LWNELEK 2859
Cdd:COG4913   785 AEEELER 791
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1313-1521 4.18e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 4.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1313 KAQLKEIEAEKVELELKVSsttsELTKKSEEVFQLQEQINKQGLEIESLKTVShEAEVHAESLQQKLESSQLQiagLEHL 1392
Cdd:COG4913   609 RAKLAALEAELAELEEELA----EAEERLEALEAELDALQERREALQRLAEYS-WDEIDVASAEREIAELEAE---LERL 680

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1393 RELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEmKQK 1472
Cdd:COG4913   681 DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----AAEDLARLELRALLE-ERF 755

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 374532817 1473 PEEIGEESRakQQIQRKLQAALisrkealkenKSLQEELSLARGTIERL 1521
Cdd:COG4913   756 AAALGDAVE--RELRENLEERI----------DALRARLNRAEEELERA 792
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1389-2031 5.22e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 5.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1389 LEHLRELQPKLDELQKLISKKEEdvsyLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDerikqlqvELCE 1468
Cdd:PRK03918  168 GEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK--------ELEE 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1469 MKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSladvesqvsaqnkekdtvlgrlal 1548
Cdd:PRK03918  236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK------------------------ 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1549 lQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLtedkEKLVKEIESLKSskiaESTEWQEKHKELQKEYEILlqsye 1628
Cdd:PRK03918  292 -AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI----EERIKELEEKEE----RLEELKKKLKELEKRLEEL----- 357

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1629 nvsneaeriqhvveavrQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSK-QQKILELEEENDRLRAE 1707
Cdd:PRK03918  358 -----------------EERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEiEEEISKITARIGELKKE 420

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1708 VhpagDTAKECMETLLSSNAS--------MKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLE 1779
Cdd:PRK03918  421 I----KELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1780 ATEKHDNQTNVTEEGTQSIPGETEEQDslsmstrptcSESVPSAKSANPAVSKDFSShdeINNYLQQIDQLKERIAGLEE 1859
Cdd:PRK03918  497 KLKELAEQLKELEEKLKKYNLEELEKK----------AEEYEKLKEKLIKLKGEIKS---LKKELEKLEELKKKLAELEK 563

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1860 EKQKNKEFSQTLENEKNTL----LSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQL 1935
Cdd:PRK03918  564 KLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAE-TEKRL 642

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1936 AELNGSIGNYCQDVTDAQIKNelLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR--KEYLEKIQGAQKEPGNKSHAK 2013
Cdd:PRK03918  643 EELRKELEELEKKYSEEEYEE--LREEYLELSRELAGLRAELEELEKRREEIKKTLEklKEELEEREKAKKELEKLEKAL 720

                         650
                  ....*....|....*...
gi 374532817 2014 ELQELLKEKQQEVKQLQK 2031
Cdd:PRK03918  721 ERVEELREKVKKYKALLK 738
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1836-2353 5.26e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.35  E-value: 5.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1836 SHDEINNYLQQ-IDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQistkdgeLKMLQEEVTKMN-LLNQQIQEELSRV 1913
Cdd:pfam15921  254 SQNKIELLLQQhQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQ-------LEIIQEQARNQNsMYMRQLSDLESTV 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1914 TKLKETAEEEKDDLEERLmnqlAELNGSIGNYCQDVTDAQIKNELLESEMKNLkkcvselEEEKQQLVKEKTKVESEIRK 1993
Cdd:pfam15921  327 SQLRSELREAKRMYEDKI----EELEKQLVLANSELTEARTERDQFSQESGNL-------DDQLQKLLADLHKREKELSL 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1994 EYLEKIQGAQKEPGNKSHAKELQELLKEKQQEV-------KQLQKDCI-RYQEKISALERTVKALEFVQTESQKdLEITK 2065
Cdd:pfam15921  396 EKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVqrleallKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQ-LESTK 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2066 ENLAQAVEHRKKAQAELASFKVLLDD--------------TQSEAARVLAD-NLKLK------------KELQSNKESVK 2118
Cdd:pfam15921  475 EMLRKVVEELTAKKMTLESSERTVSDltaslqekeraieaTNAEITKLRSRvDLKLQelqhlknegdhlRNVQTECEALK 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2119 SQMKQKDEDLERrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK----KDKEVQQLQEnLDSTVTQLAA 2194
Cdd:pfam15921  555 LQMAEKDKVIEI-LRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilKDKKDAKIRE-LEARVSDLEL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2195 FTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHME--------ELKINISRLEHDK 2266
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEtttnklkmQLKSAQSELEQTR 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2267 QIWESKA-------------QTEVQLQQKVCDTLQGENK---ELLSQLEETRHLYHSSQNELAK---------------- 2314
Cdd:pfam15921  713 NTLKSMEgsdghamkvamgmQKQITAKRGQIDALQSKIQfleEAMTNANKEKHFLKEEKNKLSQelstvateknkmagel 792

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 374532817  2315 --LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEAD 2353
Cdd:pfam15921  793 evLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 157-446 5.27e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.18  E-value: 5.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  157 EELISTLQAQLTQAQAEQPAQSSTEMEefvmMKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREK-DARFETQ- 234
Cdd:COG3096   835 EAELAALRQRRSELERELAQHRAQEQQ----LRQQLDQLKEQLQLLNKLLPQANLLADETLADRLEELREElDAAQEAQa 910

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  235 -VRLHEDELLQLVTQADVetemqqklrvLQRKLEEHEEslvgraqvvdlLQQELTAAEQRNQILSQQLQQME-----AEH 308
Cdd:COG3096   911 fIQQHGKALAQLEPLVAV----------LQSDPEQFEQ-----------LQADYLQAKEQQRRLKQQIFALSevvqrRPH 969

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  309 NTLRNTVETeREESKILLEKME--LEVAERKLSfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKtshi 386
Cdd:COG3096   970 FSYEDAVGL-LGENSDLNEKLRarLEQAEEARR--EAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQEL---- 1042

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 374532817  387 lslqktgQELQSACDALKDQNSKLLQDK-NEQAVQSAQTIQQLEDQLQQKSKEISQFLNRL 446
Cdd:COG3096  1043 -------EELGVQADAEAEERARIRRDElHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRL 1096
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1829-2067 5.67e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 5.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1829 AVSKDFSSHDEINNYLQQIDQLKERIAgleeEKQKNKEFSQTLENEKNTLLSQISTKDGELkmlqeEVTKMNLLNQQIQE 1908
Cdd:NF012221 1536 ATSESSQQADAVSKHAKQDDAAQNALA----DKERAEADRQRLEQEKQQQLAAISGSQSQL-----ESTDQNALETNGQA 1606

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1909 ELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGN-YCQDVTDAQIKNelLESEMKNLKKCVSE-LEEEKQQLVKEK 1984
Cdd:NF012221 1607 QRDAILEESRAVTKELTTLAQGLdaLDSQATYAGESGDqWRNPFAGGLLDR--VQEQLDDAKKISGKqLADAKQRHVDNQ 1684

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1985 TKVESEIRKEYLEKIQGAQKEPG-------NKSHAKELQELLKEKQQEVKQLQKDC-IRYQEKISALERTVKALEFVQTE 2056
Cdd:NF012221 1685 QKVKDAVAKSEAGVAQGEQNQANaeqdiddAKADAEKRKDDALAKQNEAQQAESDAnAAANDAQSRGEQDASAAENKANQ 1764

                         250
                  ....*....|.
gi 374532817 2057 SQKDLEITKEN 2067
Cdd:NF012221 1765 AQADAKGAKQD 1775
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 924-1642 5.94e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 5.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEfDLLKKENEQRKRKLQAA 1003
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK-REAQEEQLKKQQLLKQL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1004 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRK 1083
Cdd:TIGR00618  266 RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRR 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1084 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHW 1163
Cdd:TIGR00618  346 LLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1164 KPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDdynrlQEQFDEQSKENENIGDQLRQLQI 1243
Cdd:TIGR00618  426 LAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-----KEQIHLQETRKKAVVLARLLELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1244 QVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNlcpdwpshSEDASALQGGTSVAQIKAQLKEIEAEK 1323
Cdd:TIGR00618  501 EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE--------DVYHQLTSERKQRASLKEQMQEIQQSF 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1324 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE----------SLQQKLESSQLQIAGLEHLR 1393
Cdd:TIGR00618  573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdlqdvrlHLQQCSQELALKLTALHALQ 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1394 ELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDL--IKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1471
Cdd:TIGR00618  653 LTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLaqCQTLLRELETHIEEYDREFNEIENASSSLGS 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1472 kpeEIGEESRAKQQIQRKLQAaliSRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1551
Cdd:TIGR00618  733 ---DLAAREDALNQSLKELMH---QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1552 ERDklitemdrsllenqslssscESLKLALEGLTEDKEKLVKEIESLKsSKIAESTEWQEKHKELQKEYEILLQSYENVS 1631
Cdd:TIGR00618  807 EIG--------------------QEIPSDEDILNLQCETLVQEEEQFL-SRLEEKSATLGEITHQLLKYEECSKQLAQLT 865

                          730
                   ....*....|.
gi 374532817  1632 NEAERIQHVVE 1642
Cdd:TIGR00618  866 QEQAKIIQLSD 876
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1771-2187 6.45e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 49.13  E-value: 6.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1771 NVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTC-SESVPSAKSANPAVSKDFSSHDEINNYLQQIDQ 1849
Cdd:PLN02939   41 GFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELpQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSK 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1850 LKERIAGLEEEkqknkEFSQTLEN-EKNTLLsqistkdgelkmlqeevtkMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1928
Cdd:PLN02939  121 DGEQLSDFQLE-----DLVGMIQNaEKNILL-------------------LNQARLQALEDLEKILTEKEALQGKINILE 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1929 ERLMNQLAELNGSignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEkiqgaqkepgn 2008
Cdd:PLN02939  177 MRLSETDARIKLA--------AQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENML----------- 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2009 kshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL----EITKENLAQAVEhrkkaqaelaS 2084
Cdd:PLN02939  238 ---LKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVsklsPLQYDCWWEKVE----------N 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2085 FKVLLDDTQSE---AARVLADNLKLKKELQSNKESVKSQMKQKD-----EDLERRLEQAEEKHLKEKKNMQEKLDAlrre 2156
Cdd:PLN02939  305 LQDLLDRATNQvekAALVLDQNQDLRDKVDKLEASLKEANVSKFssykvELLQQKLKLLEERLQASDHEIHSYIQL---- 380

                         410       420       430
                  ....*....|....*....|....*....|...
gi 374532817 2157 kvhLEETIGEIQVTLNK--KDKEVQQLQENLDS 2187
Cdd:PLN02939  381 ---YQESIKEFQDTLSKlkEESKKRSLEHPADD 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2012-2230 7.01e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 7.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2012 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDD 2091
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2092 TQSEAARVLADNLKLkkelqSNKESVKSQMKQKD-EDLERR---LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEI 2167
Cdd:COG4942   102 QKEELAELLRALYRL-----GRQPPLALLLSPEDfLDAVRRlqyLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 374532817 2168 QVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2230
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 832-1074 7.54e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 48.39  E-value: 7.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  832 SEQSTLIRSLQSQ--LQNKESEVLEGAERVRHISSKVEELSQALSQ----KELEITKMDQLLLEKKRDVETLQQTIEEKD 905
Cdd:PRK05771   16 SYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDKlrsyLPKLNPLREEKKKVSVKSLEELIKDVEEEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  906 QQVTEISFSMTEKMVQLNEEKFSL-------------GVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSG-----LKQN 967
Cdd:PRK05771   96 EKIEKEIKELEEEISELENEIKELeqeierlepwgnfDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVenveyISTD 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  968 YDEMSPAGQISKEELQHEFDLLKKENEQRKRklqaaLINRKELLQRVSRLEEELANLKDeskkeiplsetERGEVEED-- 1045
Cdd:PRK05771  176 KGYVYVVVVVLKELSDEVEEELKKLGFERLE-----LEEEGTPSELIREIKEELEEIEK-----------ERESLLEElk 239

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 374532817 1046 KENKEYSEKCVTSKC------QEIEIYLKQTISEK 1074
Cdd:PRK05771  240 ELAKKYLEELLALYEyleielERAEALSKFLKTDK 274
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2306-2543 8.41e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 8.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2306 HSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMK 2385
Cdd:COG4942    16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2386 EQKIISLlsgKEEAIQVAIAELRQQHDKEIKELenLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLD 2465
Cdd:COG4942    96 RAELEAQ---KEELAELLRALYRLGRQPPLALL--LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 374532817 2466 SFVKSMSSLQNDRdrivgdyQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYRE 2543
Cdd:COG4942   171 AERAELEALLAEL-------EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 188-1053 8.94e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.43  E-value: 8.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   188 MKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVEtEMQQKLRVLQRKLE 267
Cdd:pfam02463  190 IDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIE-SSKQEIEKEEEKLA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   268 EHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNtvetEREESKILLEKMELEVAERKLSFHNLQEEM 347
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEE----KLKESEKEKKKAEKELKKEKEEIEELEKEL 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   348 HHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQEL-QSACDALKDQNSKLLQDKNEQAVQSAQTIQ 426
Cdd:pfam02463  345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKeEELELKSEEEKEAQLLLELARQLEDLLKEE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   427 QLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPdvYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAEN 506
Cdd:pfam02463  425 KKEELEILEEEEESIELKQGKLTEEKEELEKQEL--KLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKE 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   507 EKLSSQITLLEAQNRTGEADRevseISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQ 586
Cdd:pfam02463  503 SKARSGLKVLLALIKDGVGGR----IISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGAR 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   587 GKRAEEADHEVLDQKEMKqmegEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVEL 666
Cdd:pfam02463  579 KLRLLIPKLKLPLKSIAV----LEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   667 KSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLiEEFKKNADNNSSAFTA 746
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKL-EAEELLADRVQEAQDK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   747 LSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHS--------LSIEAKSKDVKIE 818
Cdd:pfam02463  734 INEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKeeklkaqeEELRALEEELKEE 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   819 VLQNELDDV---------QLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLE 889
Cdd:pfam02463  814 AELLEEEQLlieqeekikEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE 893

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   890 KKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQN-- 967
Cdd:pfam02463  894 KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEElg 973

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   968 YDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE 1047
Cdd:pfam02463  974 KVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLELGGSAELRLEDP 1053


                   ....*.
gi 374532817  1048 NKEYSE 1053
Cdd:pfam02463 1054 DDPFSG 1059
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2601-3194 9.74e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 9.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2601 EKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGE 2680
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELT---------AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2681 IEdKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELD 2760
Cdd:TIGR02168  304 KQ-ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2761 ELKRKYdaslkelAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDsynqvqsfs 2840
Cdd:TIGR02168  383 TLRSKV-------AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELE--------- 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2841 KAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH 2920
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2921 PLKAQLQEYQ-----------------DKTKAFQImQEELRQENLSWQH--ELHQLRMEKSSWEIHERRMK-EQYLMAIS 2980
Cdd:TIGR02168  527 ELISVDEGYEaaieaalggrlqavvveNLNAAKKA-IAFLKQNELGRVTflPLDSIKGTEIQGNDREILKNiEGFLGVAK 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2981 DKDQQLSHLQNLIRELRSSSS------QTQPLKVQYQRQASPET----SASPDGSQN----------LVYETEL--LRTQ 3038
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLvvddldNALELAKKLRPGYRIVTldgdLVRPGGVITggsaktnssiLERRREIeeLEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  3039 LNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAVSKEKgpLNID 3118
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL--EAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  3119 VAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERD---------------------QRVAA 3177
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlrerleslerriaaterRLEDL 843

                          650
                   ....*....|....*..
gi 374532817  3178 ENALSVAEEQIRRLEHS 3194
Cdd:TIGR02168  844 EEQIEELSEDIESLAAE 860
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
679-1130 1.25e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 1.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  679 AVPDIGQCHQDELERLKSQILELE-LNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLlsq 757
Cdd:PRK02224  177 GVERVLSDQRGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL--- 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  758 vkelsmvTELRAQVKQLEMNLAEAERQRR-LDYESQTAHDNLLT--EQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQ 834
Cdd:PRK02224  254 -------ETLEAEIEDLRETIAETEREREeLAEEVRDLRERLEEleEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  835 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV------ 908
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFgdapvd 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  909 ----TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK----EQVEEDNEVSSGLKQNYDEmspagqisKE 980
Cdd:PRK02224  407 lgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVETIEEDRER--------VE 478

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  981 ELQHEFDLLKKENEQRKRKLQAAlINRKELLQRVSRLEEELANLKDeskkeipLSETERGEVEEDKEnkeysekcvtsKC 1060
Cdd:PRK02224  479 ELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEE-------LIAERRETIEEKRE-----------RA 539

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 374532817 1061 QEieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLL------QAEISENQAIIQKL 1130
Cdd:PRK02224  540 EE----LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLerirtlLAAIADAEDEIERL 611
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 716-910 1.26e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  716 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELS-MVTELRAQVKQLEMNLAEAERQRRLDYESQTA 794
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALArRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  795 HDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 874
Cdd:COG4942   102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 374532817  875 QKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTE 910
Cdd:COG4942   182 ELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2290-2510 1.29e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2290 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ 2369
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2370 ASRE-LTSRLHEEINMKEQKIISLLSGKEEAIQVA-----IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2443
Cdd:COG4942   101 AQKEeLAELLRALYRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 374532817 2444 NQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAEN 2510
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1853-2389 1.29e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.15  E-value: 1.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1853 RIAGLEEEKQKNKEFSQT-LENEKNTLLSQIS-TKDGELKMLQEEVTKMNLLNQQIQ-EELSRVTKLKETAE----EEKD 1925
Cdd:COG5022   870 YLQSAQRVELAERQLQELkIDVKSISSLKLVNlELESEIIELKKSLSSDLIENLEFKtELIARLKKLLNNIDleegPSIE 949

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1926 DLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLE-------SEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK--EYL 1996
Cdd:COG5022   950 YVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVregnkanSELKNFKKELAELSKQYGALQESTKQLKELPVEvaELQ 1029

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1997 EKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT-KENLAQAVEHR 2075
Cdd:COG5022  1030 SASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINvKDLEVTNRNLV 1109

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2076 KKAQAE----LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDeDLERRLEQAEEKHLKEKKNMQEK-L 2150
Cdd:COG5022  1110 KPANVLqfivAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEA-NLEALPSPPPFAALSEKRLYQSAlY 1188

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2151 DALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQ---SK 2227
Cdd:COG5022  1189 DEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSllnSI 1268

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2228 EEEIRLKEDNCSVLKDQLRQMSIHMEELKINisRLEHDKQIWESKAQTEVQLQQKVCDT--LQGENKEL---LSQLEETR 2302
Cdd:COG5022  1269 DNLLSSYKLEEEVLPATINSLLQYINVGLFN--ALRTKASSLRWKSATEVNYNSEELDDwcREFEISDVdeeLEELIQAV 1346

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2303 HLYHSSQNELAKLESELKSLKDQLTDLSNSLeKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEI 2382
Cdd:COG5022  1347 KVLQLLKDDLNKLDELLDACYSLNPAEIQNL-KSRYDPADKENNLPKEILKKIEALLIKQELQLSLEGKDETEVHLSEIF 1425


                  ....*..
gi 374532817 2383 NMKEQKI 2389
Cdd:COG5022  1426 SEEKSLI 1432
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1945-2682 1.47e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 1.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1945 YCQDVTDAQIK----NELLESEMKNLKKCVSELEEEKQQLVKEKTKVeSEIRKEYLEKIQGAQKEPGNKSH----AKELQ 2016
Cdd:pfam15921   83 YSHQVKDLQRRlnesNELHEKQKFYLRQSVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHeleaAKCLK 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2017 E-LLKEKQQEVKQLQKDCIRYQEKISALERTVkaLEFVQTESQKdleITKENLAQAVEHRKKAQAelasFKVLLDDTQSE 2095
Cdd:pfam15921  162 EdMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL--VDFEEASGKK---IYEHDSMSTMHFRSLGSA----ISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2096 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2175
Cdd:pfam15921  233 ISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2176 KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDeaKKWERKFSDAIQSKEEEIRLKEDNCSvLKDQLRQM--SIHME 2253
Cdd:pfam15921  313 SMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELE--KQLVLANSELTEARTERDQFSQESGN-LDDQLQKLlaDLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2254 ELKINISRlEHDKQIWESKAQTEVQLQ-------------QKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELK 2320
Cdd:pfam15921  390 EKELSLEK-EQNKRLWDRDTGNSITIDhlrrelddrnmevQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2321 SLKDQLTDLSNSLEKCKEQKGNLEgiirQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKE--- 2397
Cdd:pfam15921  469 QLESTKEMLRKVVEELTAKKMTLE----SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDhlr 544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2398 ------EAIQVAIAE-------LRQQhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL 2464
Cdd:pfam15921  545 nvqtecEALKLQMAEkdkvieiLRQQ----IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKI 620

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2465 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQE---AAAENNKLKEEI----RGLRSHMDDLNSENAKLDAE 2537
Cdd:pfam15921  621 RELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTTNKLKMQ 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2538 LIQYREDLNQVITIKDSQQK---QLLEVQLQQNKELENKYAKLEEKLKESEEANEDL---RRSFNALQEEKQDLSKEIES 2611
Cdd:pfam15921  701 LKSAQSELEQTRNTLKSMEGsdgHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMtnaNKEKHFLKEEKNKLSQELST 780

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 374532817  2612 LKVSISQLTRQVTALQEEgtlglyHAQLKVK----EEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIE 2682
Cdd:pfam15921  781 VATEKNKMAGELEVLRSQ------ERRLKEKvanmEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
705-957 1.56e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  705 FHKAQeiyeknldeKAKEISNLNQLIEEF-------KKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMN 777
Cdd:COG4913   197 LHKTQ---------SFKPIGDLDDFVREYmleepdtFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAA 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  778 LAEAERQRRLD-----YESQTAHDnLLTEQIHSLSIEakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV 852
Cdd:COG4913   268 RERLAELEYLRaalrlWFAQRRLE-LLEAELEELRAE-------LARLEAELERLEARLDALREELDELEAQIRGNGGDR 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  853 LEGAER--------VRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNE 924
Cdd:COG4913   340 LEQLEReierlereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRR 419

                         250       260       270
                  ....*....|....*....|....*....|...
gi 374532817  925 EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEED 957
Cdd:COG4913   420 ELRELEAEIASLERRKSNIPARLLALRDALAEA 452
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1992-2185 1.99e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1992 RKEYLEKIQGaQKEPGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERTVKALEFVQTESQKDLEITK--ENLA 2069
Cdd:COG4717    54 EADELFKPQG-RKPELNLKELKELEEELKEAEEKEEEYAEL----QEELEELEEELEELEAELEELREELEKLEklLQLL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2070 QAVEHRKKAQAELASFKVLLDDTQSEAARVladnlklkKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2149
Cdd:COG4717   129 PLYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 374532817 2150 LDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:COG4717   201 LEELQQRLAELEEELEEAQEELEELEEELEQLENEL 236
PTZ00121 PTZ00121
MAEBL; Provisional
 704-1248 2.25e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 2.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  704 NFHKAQEIYEKNLDEKAKEISNlnqlIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMV---TELRAQVKQLEMNLAE 780
Cdd:PTZ00121 1210 EERKAEEARKAEDAKKAEAVKK----AEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFArrqAAIKAEEARKADELKK 1285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  781 AERQRRLDyESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAE 857
Cdd:PTZ00121 1286 AEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  858 RvrhisSKVEELSQALSQKELEITKMDQlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlneekfslgvEIKTLK 937
Cdd:PTZ00121 1365 K-----AEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAKK------------KADEAK 1424

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  938 EQLNLLSRAEEAKKEQveEDNEVSSGLKQNYDEMSPAGQISKE-ELQHEFDLLKKENEQRKRKLQAalinrKELLQRVSR 1016
Cdd:PTZ00121 1425 KKAEEKKKADEAKKKA--EEAKKADEAKKKAEEAKKAEEAKKKaEEAKKADEAKKKAEEAKKADEA-----KKKAEEAKK 1497

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1017 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQfq 1096
Cdd:PTZ00121 1498 KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED-- 1575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1097 alvKQMNQTLQDKTNQIDllQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISppctGSSEHWKPELEEKILALEK 1176
Cdd:PTZ00121 1576 ---KNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK----AEEEKKKVEQLKKKEAEEK 1646

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 374532817 1177 EKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1248
Cdd:PTZ00121 1647 KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
687-1050 2.31e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 2.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  687 HQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVT 765
Cdd:PRK02224  354 LEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELrEREA 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  766 ELRAQVKQLEMNLAEAERQRRLDYESQTAHDnlLTEQIHSLSIEakSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSqL 845
Cdd:PRK02224  430 ELEATLRTARERVEEAEALLEAGKCPECGQP--VEGSPHVETIE--EDRERVEELEAELEDLEEEVEEVEERLERAED-L 504

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  846 QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDqlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEE 925
Cdd:PRK02224  505 VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELR----ERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK 580

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  926 KFSLGVEIKTLKEQLNLLSRAEEAKkEQVEEDNEVSSGLKQNYDEmspagqiSKEELQHEFD----LLKKENEQRKRKLQ 1001
Cdd:PRK02224  581 LAELKERIESLERIRTLLAAIADAE-DEIERLREKREALAELNDE-------RRERLAEKRErkreLEAEFDEARIEEAR 652

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 374532817 1002 AALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1050
Cdd:PRK02224  653 EDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERRE 701
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1473-1712 2.40e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1473 PEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEE 1552
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1553 RDKLITEMDRSLLENQSLSSScESLKLALEGltEDKEKLVKEIESLKSSkiaestewQEKHKELQKEYEILLQSYENVSN 1632
Cdd:COG4942    99 LEAQKEELAELLRALYRLGRQ-PPLALLLSP--EDFLDAVRRLQYLKYL--------APARREQAEELRADLAELAALRA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1633 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAG 1712
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
152-330 2.44e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.93  E-value: 2.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  152 KLQEKEELISTLQAQLTQAQAEQpAQSSTEMEEF------VMMKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVR 225
Cdd:COG3206   169 RREEARKALEFLEEQLPELRKEL-EEAEAALEEFrqknglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRA 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  226 EKDARFETQVRLHEDELLQLVTQ--ADVETEMQQ----------KLRVLQRKLEEHEESLVGRAQ-VVDLLQQELTAAEQ 292
Cdd:COG3206   248 QLGSGPDALPELLQSPVIQQLRAqlAELEAELAElsarytpnhpDVIALRAQIAALRAQLQQEAQrILASLEAELEALQA 327

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 374532817  293 RNQILSQQLQQM----------EAEHNTLRNTVETEREESKILLEKME 330
Cdd:COG3206   328 REASLQAQLAQLearlaelpelEAELRRLEREVEVARELYESLLQRLE 375
PLN02939 PLN02939
transferase, transferring glycosyl groups
 631-998 3.07e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 3.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  631 PNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDeleRLKSQILELelNFHKAQE 710
Cdd:PLN02939   40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHN---RASMQRDEA--IAAIDNE 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  711 IYEKNLDEKakEISNLNqlIEEFKKNADNNSSAFTALSEERDQLLSQV-KELSMVTELRAQVKQLEMNLAEAERQRRLDY 789
Cdd:PLN02939  115 QQTNSKDGE--QLSDFQ--LEDLVGMIQNAEKNILLLNQARLQALEDLeKILTEKEALQGKINILEMRLSETDARIKLAA 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  790 ESQtAHDNLLTEQI----HSLSIEAKSKDVKIEVLQNELDDVQlqfsEQSTLIRSLQSQLQNKESEVLEGAERV------ 859
Cdd:PLN02939  191 QEK-IHVEILEEQLeklrNELLIRGATEGLCVHSLSKELDVLK----EENMLLKDDIQFLKAELIEVAETEERVfkleke 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  860 -RHISSKVEELSQALSQKELEITKMDQLLLEKKRD-VETLQQTIEEKDQQVTEISFSMT-----EKMVQLNEEKFSLGVE 932
Cdd:PLN02939  266 rSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEkVENLQDLLDRATNQVEKAALVLDqnqdlRDKVDKLEASLKEANV 345

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 374532817  933 IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiSKEELQHEFDLLKKENEQRKR 998
Cdd:PLN02939  346 SKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQE-------SIKEFQDTLSKLKEESKKRSL 404
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1849-2180 3.15e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.66  E-value: 3.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1849 QLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQIST-KDGELKMLQEEVTKMNLLNQQIQEELSRVTKlketaEEEKDDL 1927
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKaRQAEMDRQAAIYAEQERMAMERERELERIRQ-----EERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1928 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepg 2007
Cdd:pfam17380  363 ERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRAEQEEARQ------- 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2008 nkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALErtvkalefvqtesQKDLEITKENLAQAVEHRKKAQAELASFKV 2087
Cdd:pfam17380  435 -----REVRRLEEERAREMERVRLEEQERQQQVERLR-------------QQEEERKRKKLELEKEKRDRKRAEEQRRKI 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2088 LLDDTQSEAARVLADNLK---LKKELQSNKESVKSQMKQKDEDLERRleqaEEKHLKEKKNMQEKLDALRREKVHLEETI 2164
Cdd:pfam17380  497 LEKELEERKQAMIEEERKrklLEKEMEERQKAIYEEERRREAEEERR----KQQEMEERRRIQEQMRKATEERSRLEAME 572

                          330
                   ....*....|....*.
gi 374532817  2165 GEIQVTLNKKDKEVQQ 2180
Cdd:pfam17380  573 REREMMRQIVESEKAR 588
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 282-519 3.90e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  282 LLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEkmELEVAERKLSfhNLQEEMHHLLEQFEQAGQAQ 361
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLK--QLAALERRIA--ALARRIRALEQELAALEAEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  362 AELESRYSALEQKHKAEMEEKTSHILSLQKTGQelQSACDALkdqnskLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 441
Cdd:COG4942    86 AELEKEIAELRAELEAQKEELAELLRALYRLGR--QPPLALL------LSPEDFLDAVRRLQYLKYLAPARREQAEELRA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 374532817  442 FLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQ 519
Cdd:COG4942   158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
mukB PRK04863
chromosome partition protein MukB;
154-441 4.20e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 4.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  154 QEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS---------QTQA----------EQA 214
Cdd:PRK04863  347 QEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLAdyqqaldvqQTRAiqyqqavqalERA 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  215 AQLSSMQQVVREKDARFETQVRLHEDELLQLVTQAdvetemQQKLRVLQRKLEEHEESL---------VGRAQVVDLLQQ 285
Cdd:PRK04863  427 KQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSL------EQKLSVAQAAHSQFEQAYqlvrkiageVSRSEAWDVARE 500

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  286 ELTAAEQRnQILSQQLQQMEAEHNTLRNTVETEREESKILLE-KMELEVAErkLSFHNLQEEMHHLLEQFEQAGQAQAEL 364
Cdd:PRK04863  501 LLRRLREQ-RHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEfCKRLGKNL--DDEDELEQLQEELEARLESLSESVSEA 577

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 374532817  365 ESRYSALEQkhkaEMEEKTSHILSLQKTGQELQSACDALKDqnsklLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 441
Cdd:PRK04863  578 RERRMALRQ----QLEQLQARIQRLAARAPAWLAAQDALAR-----LREQSGEEFEDSQDVTEYMQQLLERERELTV 645
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
978-1608 4.39e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.21  E-value: 4.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  978 SKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLkDESKKEIPLSETERGEVEEDKENKEysekcvt 1057
Cdd:PRK03918  187 RTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKLE------- 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1058 SKCQEIEIYLKQTISEKEvELQHIRKDLEEKLAAEEQFQALVKQMNQTLqDKTNQIDLLQAEISENQAIIQKLITSNTda 1137
Cdd:PRK03918  259 EKIRELEERIEELKKEIE-ELEEKVKELKELKEKAEEYIKLSEFYEEYL-DELREIEKRLSRLEEEINGIEERIKELE-- 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1138 sdgdsvalvketvvisppctgSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDY 1217
Cdd:PRK03918  335 ---------------------EKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKEL 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1218 NRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCsstPGLEEPLfkaTEQHhtqpvlESNLCPDWPSHS 1297
Cdd:PRK03918  394 EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKC---PVCGREL---TEEH------RKELLEEYTAEL 461

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1298 EDASAlqggtSVAQIKAQLKEIEAEKVELElKVSSTTSELTKKSEEVFQLQEQINK-QGLEIESLKTVSHEAEVHAESLQ 1376
Cdd:PRK03918  462 KRIEK-----ELKEIEEKERKLRKELRELE-KVLKKESELIKLKELAEQLKELEEKlKKYNLEELEKKAEEYEKLKEKLI 535

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1377 qKLESSQLQIAG-LEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEH 1455
Cdd:PRK03918  536 -KLKGEIKSLKKeLEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKEL 614

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1456 DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqaalisrkEALKENKSlQEELSLARGTIERLTKSLADVESQVSAQ 1535
Cdd:PRK03918  615 EREEKELKKLEEELDKAFEELAETEKRLEELRKEL--------EELEKKYS-EEEYEELREEYLELSRELAGLRAELEEL 685

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 374532817 1536 NKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE 1608
Cdd:PRK03918  686 EKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEELTE 758
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2105-2690 5.66e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 5.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2105 KLKKELQSNKESVKSQMKQKDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVH-------LEETIGEIQVTLNKKD 2175
Cdd:PRK03918  193 ELIKEKEKELEEVLREINEISSELPELREELEklEKEVKELEELKEEIEELEKELESlegskrkLEEKIRELEERIEELK 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2176 KEVQQLQENLDStVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2255
Cdd:PRK03918  273 KEIEELEEKVKE-LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSR-LEEEINGIEERIKELEEKEERLEELKKKLKEL 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2256 KINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyHSSQNELAKLESELKSLKDQLTDLSNSLEK 2335
Cdd:PRK03918  351 EKRLEELEERHELYE-------------------EAKAKKEELERLKK--RLTGLTPEKLEKELEELEKAKEEIEEEISK 409

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2336 CKEQKGNLEGIIRQQEADIQNSKFSYEQLETdlqASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRqqhdKEI 2415
Cdd:PRK03918  410 ITARIGELKKEIKELKKAIEELKKAKGKCPV---CGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLR----KEL 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2416 KELENLLSqeeeeNIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQldsfvksmsslqndrdrivgDYQQLEERhlSI 2495
Cdd:PRK03918  483 RELEKVLK-----KESELIKLKELAEQLKELEEKLKKYNLEELEKKAE--------------------EYEKLKEK--LI 535

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2496 ILEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQyredlnqvitiKDSQQKQLLEVQLQQNKELENKY 2574
Cdd:PRK03918  536 KLKGEIKsLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEE-----------LGFESVEELEERLKELEPFYNEY 604

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2575 AKLEEKLKESeeanEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEegtlglyhaqlKVKEEEVHRLSALFS 2654
Cdd:PRK03918  605 LELKDAEKEL----EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK-----------KYSEEEYEELREEYL 669

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 374532817 2655 SSQKRIAELEEELvcvqKEAAKKVGEIE---DKLKKELK 2690
Cdd:PRK03918  670 ELSRELAGLRAEL----EELEKRREEIKktlEKLKEELE 704
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1310-1781 5.71e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 5.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1310 AQIKAQLKEIEAEKVELELK---VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQI 1386
Cdd:PRK03918  203 EEVLREINEISSELPELREElekLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1387 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDlikalhtqLEMQAKEHDERIKQLQVEL 1466
Cdd:PRK03918  283 KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE--------KEERLEELKKKLKELEKRL 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1467 CEMKQKPEEIgEESRAKQQIQRKLQAALISR---------KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNK 1537
Cdd:PRK03918  355 EELEERHELY-EEAKAKKEELERLKKRLTGLtpeklekelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK 433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1538 EKDT--VLGRLaLLQEERDKLITEMDRSLLE-NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE------ 1608
Cdd:PRK03918  434 AKGKcpVCGRE-LTEEHRKELLEEYTAELKRiEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKeleekl 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1609 ---WQEKHKELQKEYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1682
Cdd:PRK03918  513 kkyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEkleELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1683 MRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKEcMETLLSSNASMKEELERVKMEYETLSKKF-----QSLMSEKDSL 1757
Cdd:PRK03918  593 RLKELEPFYNEYLELKDAEKELEREEKELKKLEEE-LDKAFEELAETEKRLEELRKELEELEKKYseeeyEELREEYLEL 671

                         490       500
                  ....*....|....*....|....
gi 374532817 1758 SEEVQDLKHQIEGNVSKQANLEAT 1781
Cdd:PRK03918  672 SRELAGLRAELEELEKRREEIKKT 695
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1166-1651 5.85e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 5.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1166 ELEEKILALEKEKEQLQK---KLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1242
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDnieKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1243 IQVREsidgklpsTDQQESCSSTPGLEEPLFKATEQhhtqpvlesnlcpdwpshsedasalqggtsVAQIKAQLKEIEAE 1322
Cdd:TIGR04523  295 SEISD--------LNNQKEQDWNKELKSELKNQEKK------------------------------LEEIQNQISQNNKI 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1323 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTvsheaevHAESLQQKLESSQLQIaglehlRELQPKLDEL 1402
Cdd:TIGR04523  337 ISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK-------ENQSYKQEIKNLESQI------NDLESKIQNQ 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1403 QKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALH---TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEE 1479
Cdd:TIGR04523  404 EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTnqdSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1480 SRAKQQ---IQRKLQAALISRKEALKEN-KSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRL--ALLQEER 1553
Cdd:TIGR04523  484 LEQKQKelkSKEKELKKLNEEKKELEEKvKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkkENLEKEI 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1554 DKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIES---LKSSKIAESTEWQEKHKELQKEYEILLQSYENV 1630
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEkekKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643

                          490       500
                   ....*....|....*....|.
gi 374532817  1631 SNEAERIQHVVEAVRQEKQEL 1651
Cdd:TIGR04523  644 KQEVKQIKETIKEIRNKWPEI 664
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1908-2424 6.36e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 6.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1908 EELSRVTKLKETAEEEKDDLE---------ERLMNQLAELNgsignYCQDVTD---AQIKNELLESEMKNLKKCVSELEE 1975
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEpirelaeryAAARERLAELE-----YLRAALRlwfAQRRLELLEAELEELRAELARLEA 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1976 EKQQLVKEKTKVESEIR--KEYLEKIQGAQKEpgnkshakELQELLKEKQQEVKQLQKDCIRYQEKISALERTV----KA 2049
Cdd:COG4913   310 ELERLEARLDALREELDelEAQIRGNGGDRLE--------QLEREIERLERELEERERRRARLEALLAALGLPLpasaEE 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2050 LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDL- 2128
Cdd:COG4913   382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELp 461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2129 -----------ERRLEQA--------------EEKHLK------EKKNMQEKLDALR-REKVHLEET--------IGEIQ 2168
Cdd:COG4913   462 fvgelievrpeEERWRGAiervlggfaltllvPPEHYAaalrwvNRLHLRGRLVYERvRTGLPDPERprldpdslAGKLD 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2169 VTLNKKDKEVQQ-LQENLD----STVTQLAAFTKSMSSL----QDDRDRVIDEAKKWERK----FS--DAIQSKEEEIRL 2233
Cdd:COG4913   542 FKPHPFRAWLEAeLGRRFDyvcvDSPEELRRHPRAITRAgqvkGNGTRHEKDDRRRIRSRyvlgFDnrAKLAALEAELAE 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2234 KEDNCSVLKDQLRQMSIHMEELKINISRLEH-DKQIWESKAQTEVQLQqkvcdtlqgenkelLSQLEETRHLYHSSQNEL 2312
Cdd:COG4913   622 LEEELAEAEERLEALEAELDALQERREALQRlAEYSWDEIDVASAERE--------------IAELEAELERLDASSDDL 687

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2313 AKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE--TDLQASRELTSRLHEEINMKEQKII 2390
Cdd:COG4913   688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEdlARLELRALLEERFAAALGDAVEREL 767

                         570       580       590
                  ....*....|....*....|....*....|....
gi 374532817 2391 SllsgkeEAIQVAIAELRQQHDKEIKELENLLSQ 2424
Cdd:COG4913   768 R------ENLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 863-1112 6.67e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  863 SSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKFSLGVEIKTLKEQLNL 942
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKEIAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  943 LSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELA 1022
Cdd:COG4942    95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1023 NLKDESKKEiplsETERGEVEEDKENKEysekcvtskcqeieiylkQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQM 1102
Cdd:COG4942   175 ELEALLAEL----EEERAALEALKAERQ------------------KLLARLEKELAELAAELAELQQEAEELEALIARL 232

                         250
                  ....*....|
gi 374532817 1103 NQTLQDKTNQ 1112
Cdd:COG4942   233 EAEAAAAAER 242
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 48-384 6.74e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 6.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817    48 EDVQERLAYAEQLVVELKDIIR---QKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPT 124
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSdasRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   125 EPQ-SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLtqAQAEQPAQSSTEMEEFvmMKQQLQEKEEFISTLQ 203
Cdd:TIGR02169  771 EEDlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARL--REIEQKLNRLTLEKEY--LEKEIQELQEQRIDLK 846

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   204 AQLSQTQAEQA---AQLSSMQQVVREKdarfETQVRLHEDELLQLVTQADvetEMQQKLRVLQRKLEEHEESlvgraqvV 280
Cdd:TIGR02169  847 EQIKSIEKEIEnlnGKKEELEEELEEL----EAALRDLESRLGDLKKERD---ELEAQLRELERKIEELEAQ-------I 912

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   281 DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLqeemhhlleqfeQAGQA 360
Cdd:TIGR02169  913 EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNM------------LAIQE 980

                          330       340
                   ....*....|....*....|....
gi 374532817   361 QAELESRYSALEQKHKAEMEEKTS 384
Cdd:TIGR02169  981 YEEVLKRLDELKEKRAKLEEERKA 1004
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1312-1779 6.76e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 6.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1312 IKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKtvSHEAEVHAESLQQKLESSQlqiaglEH 1391
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN--NQKEQDWNKELKSELKNQE------KK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1392 LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQVELCEMKQ 1471
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNLESQINDLES 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1472 KPEEIGEESrakQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1551
Cdd:TIGR04523  399 KIQNQEKLN---QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1552 ERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKEL-QKEYEILLQSYENV 1630
Cdd:TIGR04523  476 SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIsDLEDELNKDDFELK 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1631 SNEaeriqhvVEAVRQEKQELYGKLRSTEANKKETEKQlqeaeqemeemkekmrkfaksKQQKILELEEENDRLRAEVhp 1710
Cdd:TIGR04523  556 KEN-------LEKEIDEKNKEIEELKQTQKSLKKKQEE---------------------KQELIDQKEKEKKDLIKEI-- 605

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 374532817  1711 agdtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLE 1779
Cdd:TIGR04523  606 ---------EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEII 665
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-307 6.79e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 6.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKakltslnkyieemkaqggtvlpte 125
Cdd:COG1196   271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA------------------------ 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  126 pQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQaQ 205
Cdd:COG1196   327 -ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE-E 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  206 LSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ 285
Cdd:COG1196   405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                         250       260
                  ....*....|....*....|..
gi 374532817  286 ELTAAEQRNQILSQQLQQMEAE 307
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGF 506
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2683-2908 6.85e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2683 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDEL 2762
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2763 KRKYDASLKELAQLKEQGLLNrerdALLSETAFsmnSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKA 2842
Cdd:COG4942   103 KEELAELLRALYRLGRQPPLA----LLLSPEDF---LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 374532817 2843 MASLQNERDHLWNELEKFRKSEEGKQRSAAQpstspaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2908
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
PRK12704 PRK12704
phosphodiesterase; Provisional
 2074-2236 6.97e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.15  E-value: 6.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2074 HRKKAQAELASFKVLLDDTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERR--LEQAEEKHLKEKKNMQEKLD 2151
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2152 ALRREKVHLEETIGEiqvtLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDD--RDRVIDEAK-KWERKFSDAIQSKE 2228
Cdd:PRK12704  104 LLEKREEELEKKEKE----LEQKQQELEKKEEELEELIEEQLQELERISGLTAEeaKEILLEKVEeEARHEAAVLIKEIE 179


                  ....*...
gi 374532817 2229 EEIRLKED 2236
Cdd:PRK12704  180 EEAKEEAD 187
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1373-1602 7.40e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 7.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1373 ESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALtkIQTEIIEQEDLIKALHTQLEmqa 1452
Cdd:COG4913   238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELE--- 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1453 kEHDERIKQLQVELCEMKQKPEEIGeeSRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQV 1532
Cdd:COG4913   313 -RLEARLDALREELDELEAQIRGNG--GDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1533 SAqnkekdtvlgRLALLQEERDKLITEMDRsllenqslssscesLKLALEGLTEDKEKLVKEIESLKSSK 1602
Cdd:COG4913   390 AA----------LLEALEEELEALEEALAE--------------AEAALRDLRRELRELEAEIASLERRK 435
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 152-370 8.28e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 8.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  152 KLQEKEELISTLQAQLTQAQAeQPAQSSTEMEEfvmMKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVRekdarf 231
Cdd:COG4942    42 ELAALKKEEKALLKQLAALER-RIAALARRIRA---LEQELAALEAELAELEKEIAELRAELEAQKEELAELLR------ 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  232 eTQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEEslvgRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTL 311
Cdd:COG4942   112 -ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEELRADLAELAALRAELEAERAELEALLAELEEE 186

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 374532817  312 RNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSA 370
Cdd:COG4942   187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1061-1523 8.65e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 8.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1061 QEIEIYLKQTISEKEVELQHIrKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDG 1140
Cdd:COG4717    53 KEADELFKPQGRKPELNLKEL-KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLY 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1141 DSVALVKETVVISPPCtgssehwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRL 1220
Cdd:COG4717   132 QELEALEAELAELPER-------LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1221 QEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQ--ESCSSTPGLEEPLFKATEQHHTQPVLESN---------- 1288
Cdd:COG4717   205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlKEARLLLLIAAALLALLGLGGSLLSLILTiagvlflvlg 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1289 -LCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKS-EEVFQLQEQINKQGLEIESLKtvsH 1366
Cdd:COG4717   285 lLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEElLELLDRIEELQELLREAEELE---E 361

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1367 EAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEdlikalHT 1446
Cdd:COG4717   362 ELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE------LE 435

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 374532817 1447 QLEMQAKEHDERIKQLQVELCEMKQKPEEIgEESRAKQQIQRKLQAALISRKEALKENKSLQeelsLARGTIERLTK 1523
Cdd:COG4717   436 ELEEELEELEEELEELREELAELEAELEQL-EEDGELAELLQELEELKAELRELAEEWAALK----LALELLEEARE 507
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1450-1739 9.44e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.28  E-value: 9.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1450 MQAKEHDERIKQLQVE-LCEMKQKPEE-IGEESRAKQQIQRKLQAALiSRKEAL-KENKSLQEELSLARGTIERLTKSLA 1526
Cdd:PLN02939  116 QTNSKDGEQLSDFQLEdLVGMIQNAEKnILLLNQARLQALEDLEKIL-TEKEALqGKINILEMRLSETDARIKLAAQEKI 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1527 DVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKE---KLVKEIESLKSS-- 1601
Cdd:PLN02939  195 HVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEErvfKLEKERSLLDASlr 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1602 ----KIAESTEWQEKHKELQkeYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETekqlqeaeq 1674
Cdd:PLN02939  275 elesKFIVAQEDVSKLSPLQ--YDCWWEKVENLQDLLDRATNQVEkaaLVLDQNQDLRDKVDKLEASLKEA--------- 343

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 374532817 1675 emeEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKME 1739
Cdd:PLN02939  344 ---NVSKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSLE 405
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1314-1777 9.57e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 9.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1314 AQLKEIEAEKVELElkvsSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQiaglEHLR 1393
Cdd:COG4717    71 KELKELEEELKEAE----EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALE----AELA 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1394 ELQPKLDELQ---KLISKKEEDVSYLSGQLSEKEAALTKI--QTEIIEQEDLIKAL--HTQLEMQAKEHDERIKQLQVEL 1466
Cdd:COG4717   143 ELPERLEELEerlEELRELEEELEELEAELAELQEELEELleQLSLATEEELQDLAeeLEELQQRLAELEEELEEAQEEL 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1467 CEMKQKPEEIGEESRAKQQIQR----KLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKekdtv 1542
Cdd:COG4717   223 EELEEELEQLENELEAAALEERlkeaRLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREK----- 297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1543 lgrlALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSS-KIAESTEWQEKHKELQKEYE 1621
Cdd:COG4717   298 ----ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELlREAEELEEELQLEELEQEIA 373

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1622 ILLQSYeNVSNEAERIQHVVEAvrQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRkfAKSKQQKILELEEEN 1701
Cdd:COG4717   374 ALLAEA-GVEDEEELRAALEQA--EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE--LEELEEELEELEEEL 448

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 374532817 1702 DRLRAEVhpagDTAKECMETLLSSN--ASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1777
Cdd:COG4717   449 EELREEL----AELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2105-2619 9.63e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 9.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2105 KLKKELQSNKESVKSQMKQKDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQ 2182
Cdd:PRK02224  199 KEEKDLHERLNGLESELAELDEEIERYEEQREqaRETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELA 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2183 EnldstvtQLAAFTKSMSSLQDDRDRVIDEAKkwerkFSDA-IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISR 2261
Cdd:PRK02224  279 E-------EVRDLRERLEELEEERDDLLAEAG-----LDDAdAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAES 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2262 LEHDKQIWESKAqtevqlqqkvcDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK-------DQLTDLSNSLE 2334
Cdd:PRK02224  347 LREDADDLEERA-----------EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRerfgdapVDLGNAEDFLE 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2335 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSrlheeinmkEQKIisllsgKEEAIQVAIAELRQQHDKE 2414
Cdd:PRK02224  416 ELREERDELREREAELEATLRTARERVEEAEALLEAGKCPEC---------GQPV------EGSPHVETIEEDRERVEEL 480

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2415 IKELENLLSQEEEENIVLEEEN--KKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERH 2492
Cdd:PRK02224  481 EAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2493 LSIILEKDQLIQEAAAENNKL---KEEIRGLRSHMDDLnSENAKLDAELIQYREDLNQVITIKDsQQKQLLEVQLQQNKE 2569
Cdd:PRK02224  561 AEAEEEAEEAREEVAELNSKLaelKERIESLERIRTLL-AAIADAEDEIERLREKREALAELND-ERRERLAEKRERKRE 638

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 374532817 2570 LENKYAKLEEKLKESEEAN-----EDLRRSFNALQEEKQDLSKEIESLKVSISQL 2619
Cdd:PRK02224  639 LEAEFDEARIEEAREDKERaeeylEQVEEKLDELREERDDLQAEIGAVENELEEL 693
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2012-2536 9.79e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 9.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2012 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERtvkalefvqtesqkdleiTKENLAQAVEHRKKAQAELASFKVLLDD 2091
Cdd:PRK02224  201 EKDLHERLNGLESELAELDEEIERYEEQREQARE------------------TRDEADEVLEEHEERREELETLEAEIED 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2092 TQSEAARVladnlklKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK--EKKNMQEKLDALRREKVHLEETIGEIQV 2169
Cdd:PRK02224  263 LRETIAET-------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDdaDAEAVEARREELEDRDEELRDRLEECRV 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2170 TLNKKDKEVQQLQENLDstvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMS 2249
Cdd:PRK02224  336 AAQAHNEEAESLREDAD----DLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2250 IHMEELKINISRLEhdkqiwESKAQTEVQLQQkVCDTLQgENKELLSQ---------LEETRHL--YHSSQNELAKLESE 2318
Cdd:PRK02224  412 DFLEELREERDELR------EREAELEATLRT-ARERVE-EAEALLEAgkcpecgqpVEGSPHVetIEEDRERVEELEAE 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2319 LKSLKDQLTDLSNSL-------------EKCKEQKGNLEGIIRQQEADIQNSKFSYEQ-------LETDLQASRELTSRL 2378
Cdd:PRK02224  484 LEDLEEEVEEVEERLeraedlveaedriERLEERREDLEELIAERRETIEEKRERAEElreraaeLEAEAEEKREAAAEA 563

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2379 HEEINMKEQKIISLlsgkeEAIQVAIAELRQQHDKeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENI 2458
Cdd:PRK02224  564 EEEAEEAREEVAEL-----NSKLAELKERIESLER-IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKR 637

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 374532817 2459 QQKAQLDSfvKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLkEEIRGLRSHMDDLNSENAKLDA 2536
Cdd:PRK02224  638 ELEAEFDE--ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL-EELEELRERREALENRVEALEA 712
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 798-1029 9.85e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 9.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  798 LLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 877
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  878 LEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEI----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAE 947
Cdd:COG4942    90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  948 EAKKEQVEEDNEVSSGLKQNYDEMspagqisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 1027
Cdd:COG4942   170 EAERAELEALLAELEEERAALEAL-------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242


                  ..
gi 374532817 1028 SK 1029
Cdd:COG4942   243 TP 244
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
48-532 1.01e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQKD-EALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGtvlptep 126
Cdd:COG4913   265 AAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG------- 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  127 QSEEQLSKhdkssteeemEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAqsstEMEEFVMMKQQLQEKEEFISTLQAQL 206
Cdd:COG4913   338 DRLEQLER----------EIERLERELEERERRRARLEALLAALGLPLPA----SAEEFAALRAEAAALLEALEEELEAL 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  207 SQTQAEQAAQLSSMQQVVREKdarfetqvrlhEDELLQLVTQAD-VETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ 285
Cdd:COG4913   404 EEALAEAEAALRDLRRELREL-----------EAEIASLERRKSnIPARLLALRDALAEALGLDEAELPFVGELIEVRPE 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  286 EL---TAAE-----QRNQIL--SQQLQQMEA--EHNTLRNTVETEREESKILLEKMELEVAE---RKLSF--HNLQEEMH 348
Cdd:COG4913   473 EErwrGAIErvlggFALTLLvpPEHYAAALRwvNRLHLRGRLVYERVRTGLPDPERPRLDPDslaGKLDFkpHPFRAWLE 552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  349 HLL------------EQFEQAGQA-----QAelesrysaleqKHKAEMEEK--TSHILSLQKTGQelqsacdalkdQNSK 409
Cdd:COG4913   553 AELgrrfdyvcvdspEELRRHPRAitragQV-----------KGNGTRHEKddRRRIRSRYVLGF-----------DNRA 610

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  410 LLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRlpLQQHETASQTSFPDVynegtqavteeNIASLQKRVVELENEK 489
Cdd:COG4913   611 KLAALEAELAELEEELAEAEERLEALEAELDALQER--REALQRLAEYSWDEI-----------DVASAEREIAELEAEL 677

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 374532817  490 GALLLSSIELEELKAENEKLSSQITllEAQNRTGEADREVSEI 532
Cdd:COG4913   678 ERLDASSDDLAALEEQLEELEAELE--ELEEELDELKGEIGRL 718
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1821-2056 1.01e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.92  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1821 PSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK-----EFSQTLENEKNTLLSQISTKDGELKMLQEE 1895
Cdd:PRK05771   36 LKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEELEKIEKEIKELEEEISELENE 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1896 VTKmnllnqqIQEELSRVTKLKETAEEEKDDLEERLMNQLAelnGSI--GNYCQDVTDAQIKNELLESEMKN-------- 1965
Cdd:PRK05771  116 IKE-------LEQEIERLEPWGNFDLDLSLLLGFKYVSVFV---GTVpeDKLEELKLESDVENVEYISTDKGyvyvvvvv 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1966 LKKCVSELEEE--KQQLVKEKTKVE---SEIRKEYLEKIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQ--- 2037
Cdd:PRK05771  186 LKELSDEVEEElkKLGFERLELEEEgtpSELIREIKEELEEIEKE------RESLLEELKELAKKYLEELLALYEYLeie 259

                         250       260
                  ....*....|....*....|
gi 374532817 2038 -EKISALERTVKALEFVQTE 2056
Cdd:PRK05771  260 lERAEALSKFLKTDKTFAIE 279
PRK12704 PRK12704
phosphodiesterase; Provisional
 197-368 1.06e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.77  E-value: 1.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  197 EFISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQvrlheDELLQLVTQADVE-TEMQQKLRVLQRKLEEHEESLVG 275
Cdd:PRK12704   26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAK-----EEIHKLRNEFEKElRERRNELQKLEKRLLQKEENLDR 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  276 RAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETE--------REESK-ILLEKMELEvaerklsfhnLQEE 346
Cdd:PRK12704  101 KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQElerisgltAEEAKeILLEKVEEE----------ARHE 170

                         170       180
                  ....*....|....*....|..
gi 374532817  347 MHHLLEQFEQAGQAQAELESRY 368
Cdd:PRK12704  171 AAVLIKEIEEEAKEEADKKAKE 192
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2290-2667 1.09e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2290 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFS--YEQLETD 2367
Cdd:COG4717    75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerLEELEER 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2368 LQASREL---TSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHD---KEIKELENLLSQEEEENIVLEEeNKKAVD 2441
Cdd:COG4717   155 LEELRELeeeLEELEAELAELQEELEELLEQLSLATEEELQDLAEELEelqQRLAELEEELEEAQEELEELEE-ELEQLE 233

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2442 KTNQLMETLKTIKKENIQQKA------------QLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAE 2509
Cdd:COG4717   234 NELEAAALEERLKEARLLLLIaaallallglggSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2510 NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKElenkyakleEKLKESEEANE 2589
Cdd:COG4717   314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA---------ALLAEAGVEDE 384

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 374532817 2590 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEEL 2667
Cdd:COG4717   385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAEL 462
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2896-3191 1.10e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2896 DRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKE-- 2973
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRErl 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2974 -----QYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdgsqnlvyETELLRTQLNDSLKEIHQ 3048
Cdd:TIGR02168  312 anlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA---------------ELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  3049 KELRIQQLNSNFSQLLEEKNTLSIQLcdtsQSLRENQQHygdllnhcavLEKQVQELQavskekgplnidvapgapQEKN 3128
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEI----ERLEARLER----------LEDRRERLQ------------------QEIE 424

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 374532817  3129 GVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRL 3191
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1335-1767 1.16e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1335 SELTKKSEEVFQLQEQINKQGL-EIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDV 1413
Cdd:COG4717    49 ERLEKEADELFKPQGRKPELNLkELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1414 SYLSgQLSEKEAALTKIQTEIIEQEDLIKALHtQLEMQAKEHDERIKQLQVELCEMKQKPEEigEESRAKQQIQRKLQAA 1493
Cdd:COG4717   129 PLYQ-ELEALEAELAELPERLEELEERLEELR-ELEEELEELEAELAELQEELEELLEQLSL--ATEEELQDLAEELEEL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1494 LISRKEALKENKSLQEELSLARGTIERLTKSLADVESQvsAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSS 1573
Cdd:COG4717   205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALE--ERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1574 CESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELyg 1653
Cdd:COG4717   283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE-- 360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1654 klrsTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLlsSNASMKEEL 1733
Cdd:COG4717   361 ----EELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL--DEEELEEEL 434

                         410       420       430
                  ....*....|....*....|....*....|....
gi 374532817 1734 ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQ 1767
Cdd:COG4717   435 EELEEELEELEEELEELREELAELEAELEQLEED 468
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
688-1120 1.20e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  688 QDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADN-------NSSAFTALSEERDQLLSQVKE 760
Cdd:PRK02224  250 REELETLEAEIEDLRETIAET----EREREELAEEVRDLRERLEELEEERDDllaeaglDDADAEAVEARREELEDRDEE 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  761 L-SMVTELRAQVKQLEmNLAEAERQRRLDYESQTAHdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 839
Cdd:PRK02224  326 LrDRLEECRVAAQAHN-EEAESLREDADDLEERAEE---LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG 401

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  840 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKK-----RDVE--TLQQTIEEKDQQVTEis 912
Cdd:PRK02224  402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEgsPHVETIEEDRERVEE-- 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  913 fsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK--EQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLK 990
Cdd:PRK02224  480 ---------LEAELEDLEEEVEEVEERLERAEDLVEAEDriERLEERREDLEELIAERRETIEEKRERAEELRERAAELE 550

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  991 KENEQRKRKLQAALINRKELLQRVSRLEEELANLKD--ESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLK 1068
Cdd:PRK02224  551 AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKEriESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLA 630

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 374532817 1069 QT---ISEKEVELQHIRkdLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEI 1120
Cdd:PRK02224  631 EKrerKRELEAEFDEAR--IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEI 683
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1581-1993 1.26e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1581 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEillqSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1660
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEE----EYAELQEELEELEEELEELEAELEELREELEKLEK 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1661 NKKETEKQLQEAEQEMEEMKEKMR-KFAKSKQQKILELEEENDRLRAEVHpagDTAKECMETLLSSNASMKEELERVKME 1739
Cdd:COG4717   124 LLQLLPLYQELEALEAELAELPERlEELEERLEELRELEEELEELEAELA---ELQEELEELLEQLSLATEEELQDLAEE 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1740 YETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTN----------VTEEGTQSIPGETEEQDSLS 1809
Cdd:COG4717   201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallaLLGLGGSLLSLILTIAGVLF 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1810 MSTRPTCSESVPSAKSANPAVSK----DFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLEnEKNTLLSQISTK 1885
Cdd:COG4717   281 LVLGLLALLFLLLAREKASLGKEaeelQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEEL 359

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1886 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER--LMNQLAELNGSIGNYCQDVTDAQIKNELLESEM 1963
Cdd:COG4717   360 EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELeeLEEQLEELLGELEELLEALDEEELEEELEELEE 439

                         410       420       430
                  ....*....|....*....|....*....|
gi 374532817 1964 KnlkkcVSELEEEKQQLVKEKTKVESEIRK 1993
Cdd:COG4717   440 E-----LEELEEELEELREELAELEAELEQ 464
46 PHA02562
endonuclease subunit; Provisional
 1850-2139 1.34e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 1.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1850 LKERIAGLEEEkqknkefSQTLENEKNTLLSQISTKdgelKMLQEEVTKMNllNQQIQEELSRVTKLKETAEEEKDDLEE 1929
Cdd:PHA02562  172 NKDKIRELNQQ-------IQTLDMKIDHIQQQIKTY----NKNIEEQRKKN--GENIARKQNKYDELVEEAKTIKAEIEE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1930 rLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEE------KQQLVKEKTKVESeirkeylekiqgaq 2003
Cdd:PHA02562  239 -LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITK-------------- 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2004 kepgNKSHAKELQ---ELLKEKQQEVKQLqkdciryqeKISALERTVKALEFvqtesQKDLEITKENLAQAVEHRKKAQA 2080
Cdd:PHA02562  304 ----IKDKLKELQhslEKLDTAIDELEEI---------MDEFNEQSKKLLEL-----KNKISTNKQSLITLVDKAKKVKA 365

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 374532817 2081 ELAsfkvllddtqseaarvladnlKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKH 2139
Cdd:PHA02562  366 AIE---------------------ELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKY 403
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2019-2230 1.38e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2019 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAAR 2098
Cdd:COG3883    18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2099 VLADNLKLKKELQS-------NKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTL 2171
Cdd:COG3883    98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 374532817 2172 NKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2230
Cdd:COG3883   178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2805-3093 1.73e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2805 LSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQpstspaevqsL 2884
Cdd:COG1196   231 LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR----------L 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2885 KKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELhplKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSW 2964
Cdd:COG1196   301 EQDIARLEERRRELEERLEELEEELAELEEELEEL---EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2965 EIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPdgsqnlvyETELLRTQLNDSLK 3044
Cdd:COG1196   378 EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE--------EEEEEEEALEEAAE 449

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 374532817 3045 EIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLN 3093
Cdd:COG1196   450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1316-1783 1.86e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.28  E-value: 1.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1316 LKEIEAEKVELElkvssttsELTKKSEEVfqlQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLREl 1395
Cdd:PRK03918  171 IKEIKRRIERLE--------KFIKRTENI---EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE- 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1396 qpKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALhTQLEMQAKEH-------------------- 1455
Cdd:PRK03918  239 --EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYiklsefyeeyldelreiekr 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1456 ----DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqAALISRKEALKENKSLQEEL-----SLARGTIERLTKSLA 1526
Cdd:PRK03918  316 lsrlEEEINGIEERIKELEEKEERLEELKKKLKELEKRL-EELEERHELYEEAKAKKEELerlkkRLTGLTPEKLEKELE 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1527 DVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRsllenqsLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIA-E 1605
Cdd:PRK03918  395 ELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEkE 467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1606 STEWQEKHKELQKEyeilLQSYENVSNEAERIQHVVEAVRQEKqELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK 1685
Cdd:PRK03918  468 LKEIEEKERKLRKE----LRELEKVLKKESELIKLKELAEQLK-ELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIK 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1686 FAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLK 1765
Cdd:PRK03918  543 SLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELK 622

                         490
                  ....*....|....*...
gi 374532817 1766 HQIEGNVSKQANLEATEK 1783
Cdd:PRK03918  623 KLEEELDKAFEELAETEK 640
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1498-2266 1.94e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.19  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1498 KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESL 1577
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1578 KLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1657
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1658 TEAN----KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTaKECMETLLSSNASMKEEL 1733
Cdd:pfam02463  336 EIEElekeLKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEE-LELKSEEEKEAQLLLELA 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1734 ERVKMEYETLSKK-------------FQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHdnqtNVTEEGTQSIPG 1800
Cdd:pfam02463  415 RQLEDLLKEEKKEeleileeeeesieLKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ----LVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1801 ETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1880
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1881 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLK------ETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQI 1954
Cdd:pfam02463  571 TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQldkatlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1955 KNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCI 2034
Cdd:pfam02463  651 GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2035 RYQEKISALERTVKALEFVQTEsqkDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK 2114
Cdd:pfam02463  731 QDKINEELKLLKQKIDEEEEEE---EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2115 ESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeiqvTLNKKDKEVQQLQENLDSTVTQLAA 2194
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELE-----RLEEEITKEELLQELLLKEEELEEQ 882

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 374532817  2195 FTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDK 2266
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENN 954
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2271-2480 1.97e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2271 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ 2350
Cdd:COG4942    30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2351 EADIQ-NSKFSYEQL----ETDLQASRELtsRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQE 2425
Cdd:COG4942   110 LRALYrLGRQPPLALllspEDFLDAVRRL--QYLKYLAPARREQAEELRADLAELAALRAELEAER-AELEALLAELEEE 186

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 374532817 2426 EEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDR 2480
Cdd:COG4942   187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2448-2666 2.04e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2448 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2527
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2528 NSENAKLDAELIQ-----YREDLNQVITIKDSQQ------------KQLLEVQLQQNKELENKYAKLEEKLKESEEANED 2590
Cdd:COG4942    96 RAELEAQKEELAEllralYRLGRQPPLALLLSPEdfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 374532817 2591 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhAQLKVKEEEVHRLSALFSSSQKRIAELEEE 2666
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEKELAELA---------AELAELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1067-1251 2.07e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1067 LKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL---ITSNTDASDGDSV 1143
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELraeLEAQKEELAELLR 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1144 ALVKETVVISPPCTGSSEHWK-------------PELEEKILALEKEKEQLQkKLQEALTSRKAILKKAQEKERHLREEL 1210
Cdd:COG4942   112 ALYRLGRQPPLALLLSPEDFLdavrrlqylkylaPARREQAEELRADLAELA-ALRAELEAERAELEALLAELEEERAAL 190

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 374532817 1211 KQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1251
Cdd:COG4942   191 EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1338-1765 2.25e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 2.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1338 TKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE-SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYL 1416
Cdd:pfam15921  408 TGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAK 487

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1417 SGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelcEMKQKpeeiGEESRAKQQIQRKLQAALIS 1496
Cdd:pfam15921  488 KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ----HLKNE----GDHLRNVQTECEALKLQMAE 559

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1497 RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLlenqslsSSCES 1576
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARV-------SDLEL 632

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1577 LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLR 1656
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1657 STEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHpagdtakecmeTLLSSNASMKEELERV 1736
Cdd:pfam15921  713 NTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKH-----------FLKEEKNKLSQELSTV 781

                          410       420
                   ....*....|....*....|....*....
gi 374532817  1737 KMEYETLSKKFQSLMSEKDSLSEEVQDLK 1765
Cdd:pfam15921  782 ATEKNKMAGELEVLRSQERRLKEKVANME 810
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 284-1089 2.45e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.81  E-value: 2.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   284 QQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEvaerklsfhnlQEEMHHLLEQFEQAGQAQAE 363
Cdd:pfam02463  215 LKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKE-----------EEKLAQVLKENKEEEKEKKL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   364 LESRYSALEQKHKAEMEEKTSHILSLQKTGQELQsacdALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFL 443
Cdd:pfam02463  284 QEEELKLLAKEEEELKSELLKLERRKVDDEEKLK----ESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   444 NRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTG 523
Cdd:pfam02463  360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   524 EADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEM 603
Cdd:pfam02463  440 ELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDG 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   604 KQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDI 683
Cdd:pfam02463  520 VGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEI 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   684 GQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK------------AKEISNLNQLIEEFKKNADNNSSAFTALSEER 751
Cdd:pfam02463  600 DPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTklkesakakesgLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   752 DQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQF 831
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   832 SEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQT-IEEKDQQVTE 910
Cdd:pfam02463  760 EEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEkIKEEELEELA 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   911 ISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLK 990
Cdd:pfam02463  840 LELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEI 919

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   991 KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDES-KKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQ 1069
Cdd:pfam02463  920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEeEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKER 999

                          810       820
                   ....*....|....*....|
gi 374532817  1070 TISEKEVELQHIRKDLEEKL 1089
Cdd:pfam02463 1000 LEEEKKKLIRAIIEETCQRL 1019
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2310-2935 2.62e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.47  E-value: 2.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2310 NELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI 2389
Cdd:TIGR04523   40 KKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQK 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2390 ISLlsgkeeaiqvaiaelrqqhDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVK 2469
Cdd:TIGR04523  120 NKL-------------------EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2470 SMSSLQNDRDRIVGDYQQLEERhLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVI 2549
Cdd:TIGR04523  181 EKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLK 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2550 TIKDSQQKQLLEVQLQQNKElenkyakleeklkeseeanedlrrsfnalQEEKQDLSKEIESLKVSISQLTRQvtalQEE 2629
Cdd:TIGR04523  260 DEQNKIKKQLSEKQKELEQN-----------------------------NKKIKELEKQLNQLKSEISDLNNQ----KEQ 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2630 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEiEDKLKKELKHLHHDAGIMRNETETAEER 2709
Cdd:TIGR04523  307 DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESE-NSEKQRELEEKQNEIEKLKKENQSYKQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2710 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK-EQGLLNRERDA 2788
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKElIIKNLDNTRES 465

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2789 L---LSETAFSMNSTEENslshLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL-------- 2857
Cdd:TIGR04523  466 LetqLKVLSRSINKIKQN----LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKkekeskis 541

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2858 ---EKFRKSEEGKQRSA--AQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDK 2932
Cdd:TIGR04523  542 dleDELNKDDFELKKENleKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEK 621


                   ...
gi 374532817  2933 TKA 2935
Cdd:TIGR04523  622 AKK 624
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2701-2928 2.75e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2701 NETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQg 2780
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE- 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2781 lLNRERDALlsetafsmnsteENSLSHLEKLNQQllsKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKF 2860
Cdd:COG4942    99 -LEAQKEEL------------AELLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 374532817 2861 RKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKEL----KNLQQQYLQINQEITELHPLKAQLQE 2928
Cdd:COG4942   163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLekelAELAAELAELQQEAEELEALIARLEA 234
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
254-441 2.77e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  254 EMQQKLRVLQRKLEEH--EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMEL 331
Cdd:COG3206   186 ELRKELEEAEAALEEFrqKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVI 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  332 EVAERKLSfhNLQEEMHHLLEQF----EQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQN 407
Cdd:COG3206   266 QQLRAQLA--ELEAELAELSARYtpnhPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARL 343

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 374532817  408 SKLLQDKNEQAV--QSAQTIQQLEDQLQQKSKEISQ 441
Cdd:COG3206   344 AELPELEAELRRleREVEVARELYESLLQRLEEARL 379
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1845-2084 2.87e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1845 QQIDQLKERIAGLEEE----KQKNKEFSqtLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRvtKLKETA 1920
Cdd:COG3206   182 EQLPELRKELEEAEAAleefRQKNGLVD--LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS--GPDALP 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1921 EEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQiknelleSEMKNLKkcvSELEEEKQQLVKEKTKVESEIRKEYLekiq 2000
Cdd:COG3206   258 ELLQSPVIQQLRAQLAELEAELAELSARYTPNH-------PDVIALR---AQIAALRAQLQQEAQRILASLEAELE---- 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2001 gaqkepGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERtvkalefvqtesqkDLEITKENLAQAVEHRKKAQA 2080
Cdd:COG3206   324 ------ALQAREASLQAQLAQLEARLAELPEL----EAELRRLER--------------EVEVARELYESLLQRLEEARL 379


                  ....
gi 374532817 2081 ELAS 2084
Cdd:COG3206   380 AEAL 383
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 837-1240 2.95e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 2.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   837 LIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKM------DQLLLEKKRDVETLQQTIEEKDQQVTE 910
Cdd:pfam05483  364 LLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELkkilaeDEKLLDEKKQFEKIAEELKGKEQELIF 443

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   911 ISFSMTEKMVQLNEEKFSLGV-EIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLL 989
Cdd:pfam05483  444 LLQAREKEIHDLEIQLTAIKTsEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDII 523

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   990 --KKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYL 1067
Cdd:pfam05483  524 ncKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQI 603

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1068 KQTISEKEvELQHIRKDLEEKLAAEE--------QFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASd 1139
Cdd:pfam05483  604 ENKNKNIE-ELHQENKALKKKGSAENkqlnayeiKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAK- 681

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1140 gdsvALVKETVVISPPCTGSSEHwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKER---HLREELKQQKDD 1216
Cdd:pfam05483  682 ----AIADEAVKLQKEIDKRCQH---KIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSakaALEIELSNIKAE 754

                          410       420
                   ....*....|....*....|....
gi 374532817  1217 YNRLQEQFDEQSKENENIGDQLRQ 1240
Cdd:pfam05483  755 LLSLKKQLEIEKEEKEKLKMEAKE 778
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1838-2071 3.09e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 3.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1838 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKmnlLNQQIQEelsRVTKLK 1917
Cdd:COG3883    16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAE---AEAEIEE---RREELG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1918 ETAEEEKddLEERLMNQLAELNGSignycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEirkeyLE 1997
Cdd:COG3883    90 ERARALY--RSGGSVSYLDVLLGS-----ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAK-----LA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 374532817 1998 KIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2071
Cdd:COG3883   158 ELEALKAE--LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2408-2625 3.14e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2408 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDY-- 2485
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELae 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2486 -----QQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdaeliqyrEDLNQVITIKDSQQKQLL 2560
Cdd:COG4942   109 llralYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 374532817 2561 EVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTA 2625
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 665-1241 3.19e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 43.50  E-value: 3.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   665 ELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAqeIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAF 744
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLL 1196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   745 TALSE-ERDQL-LSQVKELSMVTELRAQVKQLEmNLAEAERQRRLDYESQTAH----DNLLTEQIHSLSIEAKSKDVK-- 816
Cdd:TIGR01612 1197 NEIAEiEKDKTsLEEVKGINLSYGKNLGKLFLE-KIDEEKKKSEHMIKAMEAYiedlDEIKEKSPEIENEMGIEMDIKae 1275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   817 IEVLQNELDDVQLQFSEQSTLIRSLqSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVET 896
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNI 1354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   897 LQ-QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLlsRAEEAKKEQVEEDNEVSsGLKQNYDEMSPAG 975
Cdd:TIGR01612 1355 LKlNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINL--EECKSKIESTLDDKDID-ECIKKIKELKNHI 1431

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   976 QISKEELQHEFDLLKKENEQrkrklqaALINRKELLQRVSRLEEELANLKDESKKEIPLSetergeVEEDKENKEYSEKC 1055
Cdd:TIGR01612 1432 LSEESNIDTYFKNADENNEN-------VLLLFKNIEMADNKSQHILKIKKDNATNDHDFN------INELKEHIDKSKGC 1498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1056 VTskcqEIEIYLKQTISEKEVELQHiRKDLEE------KLAAEEQFQALVKQMNQTL---QDKTNQIdLLQAEISENQ-- 1124
Cdd:TIGR01612 1499 KD----EADKNAKAIEKNKELFEQY-KKDVTEllnkysALAIKNKFAKTKKDSEIIIkeiKDAHKKF-ILEAEKSEQKik 1572

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1125 AIIQKLITSNTDASDGD--SVALVKETVVISPpctgssehwkpeLEEKILALEkekeQLQKKLQEALTSRKAILKKAQEK 1202
Cdd:TIGR01612 1573 EIKKEKFRIEDDAAKNDksNKAAIDIQLSLEN------------FENKFLKIS----DIKKKINDCLKETESIEKKISSF 1636

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 374532817  1203 ERHLRE-ELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1241
Cdd:TIGR01612 1637 SIDSQDtELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1962-2394 3.21e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.53  E-value: 3.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1962 EMKNLKKCVSEL--EEEKQQLVKEKTKVESEIRKEYLekIQGAQKEPGNKSHAKEL--QELLKEKQQEVKQLQKDCIRYQ 2037
Cdd:COG5022   811 EYRSYLACIIKLqkTIKREKKLRETEEVEFSLKAEVL--IQKFGRSLKAKKRFSLLkkETIYLQSAQRVELAERQLQELK 888

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2038 E---KISALERTVKALEFVQTESQKDLEitkENLAQAVEHRKKAQAELasfKVLLDDTQSEaarvladnlklkkeLQSNK 2114
Cdd:COG5022   889 IdvkSISSLKLVNLELESEIIELKKSLS---SDLIENLEFKTELIARL---KKLLNNIDLE--------------EGPSI 948

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2115 ESVKSQMKQKDEDLERRLEQAEEkhlkEKKNMQEKLDALRREkvhleetigeiqvtLNKKDKEVQQLQENLDSTVTQLAA 2194
Cdd:COG5022   949 EYVKLPELNKLHEVESKLKETSE----EYEDLLKKSTILVRE--------------GNKANSELKNFKKELAELSKQYGA 1010

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2195 FTKSMSSLQDdRDRVIDEAKKWERKFSDaiQSKEEEIRLKEDNC-SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKA 2273
Cdd:COG5022  1011 LQESTKQLKE-LPVEVAELQSASKIISS--ESTELSILKPLQKLkGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLE 1087

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2274 QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESElKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ---- 2349
Cdd:COG5022  1088 STENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEIS-KFLSQLVNTLEPVFQKLSVLQLELDGLFWEanle 1166

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 374532817 2350 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLS 2394
Cdd:COG5022  1167 ALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLKNELIALFS 1211
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2112-2724 3.30e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.29  E-value: 3.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2112 SNKESVKSQMKQKDEDLERRLEqaEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQvTLNKKDKEVQQLQENLDSTV-T 2190
Cdd:pfam12128  207 EDDGVVPPKSRLNRQQVEHWIR--DIQAIAGIMKIRPEFTKLQQEFNTLESAELRLS-HLHFGYKSDETLIASRQEERqE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2191 QLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKD-----------QLRQMSIHMEELKINI 2259
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDadietaaadqeQLPSWQSELENLEERL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2260 SRLEHDKQIWESKAQTEVQLQQKVC-DTLQGENKELLSQLEETRHLYHSSQNELAKLESELKS-LKDQLTDLSNSLEKCK 2337
Cdd:pfam12128  364 KALTGKHQDVTAKYNRRRSKIKEQNnRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREqLEAGKLEFNEEEYRLK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2338 EQKGNLEGIIRQQEADiqnskfsyEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQQHDKEIKE 2417
Cdd:pfam12128  444 SRLGELKLRLNQATAT--------PELLLQLENFDERIERAREEQEAANAEV--------ERLQSELRQARKRRDQASEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2418 LENLLSQEEEENIVLEEENKKAVDKTNQLMETLKtikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHL-SII 2496
Cdd:pfam12128  508 LRQASRRLEERQSALDELELQLFPQAGTLLHFLR---KEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLyGVK 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2497 LEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYredlnqvitikdsqqkqllevqlqqNKELENKYA 2575
Cdd:pfam12128  585 LDLKRIdVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQA-------------------------NGELEKASR 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2576 KLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLK----VSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLS- 2650
Cdd:pfam12128  640 EETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKdsanERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAy 719

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 374532817  2651 --ALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDagimrnetetaEERVAELARDLVEMEQKL 2724
Cdd:pfam12128  720 wqVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVD-----------PDVIAKLKREIRTLERKI 784
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 463-1250 3.40e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 3.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   463 YNEGTQAVTEENIASLQKRVVELENEKGALLLS----SIELEELKAENEKLSSQITLLEAQNrtGEADREVSEIsivdia 538
Cdd:TIGR02168  215 YKELKAELRELELALLVLRLEELREELEELQEElkeaEEELEELTAELQELEEKLEELRLEV--SELEEEIEEL------ 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   539 nkrsssaeesgQDVLENTfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEgiapikmkv 618
Cdd:TIGR02168  287 -----------QKELYAL-ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK--------- 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   619 fLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTsEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQI 698
Cdd:TIGR02168  346 -LEELKEELESLEAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   699 LELELNFHKAQ-EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMN 777
Cdd:TIGR02168  424 EELLKKLEEAElKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   778 LAEAERQRRLDYESQTAHDNLLTEQIH-----SLSIEA----KSKDVKIEVLQNELDDVQLQFSEQS------------- 835
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILGVLSELISvdegyEAAIEAalggRLQAVVVENLNAAKKAIAFLKQNELgrvtflpldsikg 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   836 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRdvETLQQTIEEKDQQVTEISFSM 915
Cdd:TIGR02168  584 TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDGDLVRPGGVI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   916 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEdnevSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQ 995
Cdd:TIGR02168  662 TGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   996 RKRKLQAalinrkeLLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIyLKQTISEKE 1075
Cdd:TIGR02168  738 LEAEVEQ-------LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA-LREALDELR 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1076 VELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPP 1155
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1156 CTGSSEhwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1235
Cdd:TIGR02168  890 ALLRSE--LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE 967

                          810
                   ....*....|....*
gi 374532817  1236 DQLRQLQIQVRESID 1250
Cdd:TIGR02168  968 EEARRRLKRLENKIK 982
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1166-1242 3.50e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 3.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1166 ELEEKILALEKEKEQLQKKLQEALTSRKAILKK----AQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1241
Cdd:COG0542   415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDelaeLEEELEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494


                  .
gi 374532817 1242 Q 1242
Cdd:COG0542   495 A 495
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1919-2150 3.71e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 3.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1919 TAEEEKDDLEERLMN----QLAELNGSIGNYcqdvtdaqiKNELLESEMKNLKKCVSELEEEKQqlvKEKTKVESEIRKE 1994
Cdd:PRK05771   13 TLKSYKDEVLEALHElgvvHIEDLKEELSNE---------RLRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1995 YLEKIQGAQKEPGNKShakELQELLKEKQQEVKQLQKDCIRYQEKISALE---------------RTVKA---------- 2049
Cdd:PRK05771   81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlslllgfKYVSVfvgtvpedkl 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2050 LEFVQTESQKDLEITKEN-------LAQAVEHRKKAQAELASFKVLLDDTQSE--AARVLADNLKLKKELQSNKESVKSQ 2120
Cdd:PRK05771  158 EELKLESDVENVEYISTDkgyvyvvVVVLKELSDEVEEELKKLGFERLELEEEgtPSELIREIKEELEEIEKERESLLEE 237

                         250       260       270
                  ....*....|....*....|....*....|..
gi 374532817 2121 MKQKDEDLERRLEQAEEK--HLKEKKNMQEKL 2150
Cdd:PRK05771  238 LKELAKKYLEELLALYEYleIELERAEALSKF 269
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1385-1566 4.05e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 4.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1385 QIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQV 1464
Cdd:COG1579     5 DLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIK----RLELEIEEVEARIKKYEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1465 ELcEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTvlg 1544
Cdd:COG1579    81 QL-GNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA--- 156

                         170       180
                  ....*....|....*....|..
gi 374532817 1545 RLALLQEERDKLITEMDRSLLE 1566
Cdd:COG1579   157 ELEELEAEREELAAKIPPELLA 178
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 714-1251 4.07e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 4.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   714 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELsmvtelRAQVKQLEMNLAEAERQRrLDYESQT 793
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDL------KKQKEELENELNLLEKEK-LNIQKNI 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   794 AHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQAL 873
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   874 SQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKF---------------SLGVEIKTLKE 938
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLeeiqnqisqnnkiisQLNEQISQLKK 349

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   939 QLNLLSRAEEAKKEQVEEDNEVSSGLK---QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS 1015
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKkenQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1016 RLEEELANLKDESKkeiplsetergeveeDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQF 1095
Cdd:TIGR04523  430 RLKETIIKNNSEIK---------------DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1096 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL----ITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEE-- 1169
Cdd:TIGR04523  495 EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLesekKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEElk 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1170 -KILALEKEKEQLQKKLQEALTSRKAILKKAQEKERhLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1248
Cdd:TIGR04523  575 qTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEK-KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653


                   ...
gi 374532817  1249 IDG 1251
Cdd:TIGR04523  654 IKE 656
PRK09039 PRK09039
peptidoglycan -binding protein;
2698-2832 4.09e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.26  E-value: 4.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2698 IMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK 2777
Cdd:PRK09039   43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELA 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 374532817 2778 EQglLNRERDalLSETAfsmnsteensLSHLEKLNQQLLSKDEQLLHLSSQLEDS 2832
Cdd:PRK09039  123 QE--LDSEKQ--VSARA----------LAQVELLNQQIAALRRQLAALEAALDAS 163
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2288-2919 4.30e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.97  E-value: 4.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2288 QGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLegiiRQQEADIQNSKFSYEQLETD 2367
Cdd:PRK01156  137 QGEMDSLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKL----KSSNLELENIKKQIADDEKS 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2368 LQASRELTSRLHEEINMKEQKIISLLSGKEEAIqvAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLM 2447
Cdd:PRK01156  213 HSITLKEIERLSIEYNNAMDDYNNLKSALNELS--SLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPV 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2448 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDrdrivgdyqqleerhlsiiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2527
Cdd:PRK01156  291 YKNRNYINDYFKYKNDIENKKQILSNIDAE-------------------INKYHAIIKKLSVLQKDYNDYIKKKSRYDDL 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2528 NSENAKLDAELIQYREDLNQVITIKDSQQkqllevqlQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSK 2607
Cdd:PRK01156  352 NNQILELEGYEMDYNSYLKSIESLKKKIE--------EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISS 423

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2608 EIESLKVSISQLTRQVTALQEEGTLGLYHAQLKV-----KEEEVHRLSALFSSSQKRiaeLEEELVCVQKEAAKkvgeIE 2682
Cdd:PRK01156  424 KVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVcgttlGEEKSNHIINHYNEKKSR---LEEKIREIEIEVKD----ID 496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2683 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVtKENKGLTAQIQSFGRSMsslqnsrdhaneELDEL 2762
Cdd:PRK01156  497 EKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINEL-KDKHDKYEEIKNRYKSL------------KLEDL 563

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2763 KRKYDASLKELAQLKEQGLLN-----RERDALLSETAFSMNSTEENsLSHLEKLNQQLLSKDEQLLHLssqLEDSYNQVQ 2837
Cdd:PRK01156  564 DSKRTSWLNALAVISLIDIETnrsrsNEIKKQLNDLESRLQEIEIG-FPDDKSYIDKSIREIENEANN---LNNKYNEIQ 639

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2838 SFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT 2917
Cdd:PRK01156  640 ENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRIN 719


                  ..
gi 374532817 2918 EL 2919
Cdd:PRK01156  720 DI 721
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 694-1485 4.35e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 4.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   694 LKSQILELELNFHKAQEIYEKNLDEkAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQ 773
Cdd:TIGR00606  222 IRDQITSKEAQLESSREIVKSYENE-LDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTD 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   774 LEMNLAEAERQRRLDYESQTAHDnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV- 852
Cdd:TIGR00606  301 EQLNDLYHNHQRTVREKERELVD--CQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLe 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   853 LEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQtieekdQQVTEISFSMTEKMVQLNEEKFSLGVE 932
Cdd:TIGR00606  379 LDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQ------EQADEIRDEKKGLGRTIELKKEILEKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   933 IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQ--NYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINR-KE 1009
Cdd:TIGR00606  453 QEELKFVIKELQQLEGSSDRILELDQELRKAERElsKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHhTT 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1010 LLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY------LKQTISEKEVELQHIRK 1083
Cdd:TIGR00606  533 TRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTrdrlakLNKELASLEQNKNHINN 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1084 DLEEKLAAEEQFQALVKQMNQTlQDKTNQIDLLQAEIsENQAIIQKLITSNTDASDGDSVALVKETVVISPPC------T 1157
Cdd:TIGR00606  613 ELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEI-EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCqrvfqtE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1158 GSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQ 1237
Cdd:TIGR00606  691 AELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQ 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1238 LRQLqiqvrESIDGKLPSTdqqESCSSTPGLEEPLFKATEQHHTQpvlesnlcpdWPSHSEDASALQGGTSVAQIKAQLK 1317
Cdd:TIGR00606  771 ETLL-----GTIMPEEESA---KVCLTDVTIMERFQMELKDVERK----------IAQQAAKLQGSDLDRTVQQVNQEKQ 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1318 EIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE-LQ 1396
Cdd:TIGR00606  833 EKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEqDS 912

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1397 PKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE----IIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1472
Cdd:TIGR00606  913 PLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKvkniHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKH 992

                          810
                   ....*....|...
gi 374532817  1473 PEEIGEESRAKQQ 1485
Cdd:TIGR00606  993 QEKINEDMRLMRQ 1005
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1300-1493 4.42e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1300 ASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLeieslktvsheaevhaeslqQKL 1379
Cdd:COG4913   281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG--------------------DRL 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1380 ESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDER 1458
Cdd:COG4913   341 EQLEREIERLErELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 374532817 1459 IKQLQVELCEMKQKPEEIGEES-RAKQQIQRKLQAA 1493
Cdd:COG4913   421 LRELEAEIASLERRKSNIPARLlALRDALAEALGLD 456
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
281-538 4.81e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 4.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  281 DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSfhnlqeemhHLLEQFEQAGQA 360
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLS---------ELESQLAEARAE 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  361 QAELESRYSALEQKHKAEMEEKTSHILS--LQKTGQELQSAcDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKE 438
Cdd:COG3206   235 LAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAEL-EAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQR 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  439 ISQFLnrlplqqhetasqtsfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEklSSQITLLEA 518
Cdd:COG3206   314 ILASL---------------------EAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVE--VARELYESL 370

                         250       260
                  ....*....|....*....|....
gi 374532817  519 QNRTGEAD----REVSEISIVDIA 538
Cdd:COG3206   371 LQRLEEARlaeaLTVGNVRVIDPA 394
PTZ00121 PTZ00121
MAEBL; Provisional
 1976-2515 4.86e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 4.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1976 EKQQLVKEKTKVESEIRKEylEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQT 2055
Cdd:PTZ00121 1221 EDAKKAEAVKKAEEAKKDA--EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKA 1298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2056 ESQKDLEITK----------ENLAQAVEHRKKAQA--ELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ 2123
Cdd:PTZ00121 1299 EEKKKADEAKkkaeeakkadEAKKKAEEAKKKADAakKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2124 KDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEiqvTLNKKDKEVQQLQEnLDSTVTQLAAFTKSMSSLQ 2203
Cdd:PTZ00121 1379 KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD---EAKKKAEEKKKADE-AKKKAEEAKKADEAKKKAE 1454

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2204 DDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDncsvLKDQLRQMSIHMEELKiniSRLEHDKQIWESKAQTEVQLQQKV 2283
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE----AKKKAEEAKKKADEAK---KAAEAKKKADEAKKAEEAKKADEA 1527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2284 CDTLQGENKELLSQLEETRhlyhsSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQ 2363
Cdd:PTZ00121 1528 KKAEEAKKADEAKKAEEKK-----KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE 1602

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2364 LETDLQASReltSRLHEEINMKEQKIisllsGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2443
Cdd:PTZ00121 1603 EEKKMKAEE---AKKAEEAKIKAEEL-----KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 374532817 2444 NQLMETLKT--IKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2515
Cdd:PTZ00121 1675 KKAEEAKKAeeDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2589-2999 4.97e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 4.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2589 EDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhaqlkvKEEEVHRLSALFSSSQKRIAELEEELv 2668
Cdd:COG4717    84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLE--------------KLLQLLPLYQELEALEAELAELPERL- 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2669 cvqkeaakkvgeieDKLKKELKHLHHdagiMRNETETAEERVAELARDLVEMEQKLLMVTKEnkgltaQIQSFGRSMSSL 2748
Cdd:COG4717   149 --------------EELEERLEELRE----LEEELEELEAELAELQEELEELLEQLSLATEE------ELQDLAEELEEL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2749 QNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQ 2828
Cdd:COG4717   205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLG 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2829 LEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSE--EGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQ 2906
Cdd:COG4717   285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEEleELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2907 QQYLQINQE----------ITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYL 2976
Cdd:COG4717   365 LEELEQEIAallaeagvedEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEEL 444

                         410       420
                  ....*....|....*....|....
gi 374532817 2977 MA-ISDKDQQLSHLQNLIRELRSS 2999
Cdd:COG4717   445 EEeLEELREELAELEAELEQLEED 468
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1308-1508 5.06e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 5.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1308 SVAQIKAQLKEIEAEKVELELKVSS--TTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1385
Cdd:COG3206   176 ALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1386 IAGLEHLRELQPKLDELQKLISKKEEdvsyLSGQLSEKEAALTKIQTEIIEQEDLIKA----LHTQLEMQAKEHDERIKQ 1461
Cdd:COG3206   256 LPELLQSPVIQQLRAQLAELEAELAE----LSARYTPNHPDVIALRAQIAALRAQLQQeaqrILASLEAELEALQAREAS 331

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 374532817 1462 LQVELCEMKQKPEEIGEESRAKQQIQRKLQAA------LISRKEALKENKSLQ 1508
Cdd:COG3206   332 LQAQLAQLEARLAELPELEAELRRLEREVEVArelyesLLQRLEEARLAEALT 384
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1456-1708 5.49e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 5.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1456 DERIKQLQ----VELCEMKQkpEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGT-----IERLTKSLA 1526
Cdd:PRK05771   19 DEVLEALHelgvVHIEDLKE--ELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKsleelIKDVEEELE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1527 DVESQVSAQNKEkdtvlgrLALLQEERDKLITEMDR-SLLENQSLS----SSCESLKLALEGLTEDKEKLVKEIESLKSS 1601
Cdd:PRK05771   97 KIEKEIKELEEE-------ISELENEIKELEQEIERlEPWGNFDLDlsllLGFKYVSVFVGTVPEDKLEELKLESDVENV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1602 KIAESTEwqEK-------HKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrstEANKKETEKQLqeaeq 1674
Cdd:PRK05771  170 EYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL-------EEIEKERESLL----- 235

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 374532817 1675 emeemkEKMRKFAKSKQQKILELEE--ENDRLRAEV 1708
Cdd:PRK05771  236 ------EELKELAKKYLEELLALYEylEIELERAEA 265
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2520-2722 5.85e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 5.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2520 LRSHMDDLNSENAKLDAELIQYREDLNQvitikdsqqkqlLEVQLQQNKElENKYAKLEEKLKESEEANEDLRRSFNALQ 2599
Cdd:COG3206   166 LELRREEARKALEFLEEQLPELRKELEE------------AEAALEEFRQ-KNGLVDLSEEAKLLLQQLSELESQLAEAR 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2600 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVG 2679
Cdd:COG3206   233 AELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 374532817 2680 EIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2722
Cdd:COG3206   313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
46 PHA02562
endonuclease subunit; Provisional
 2543-2779 6.02e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 6.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2543 EDL--NQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQD----LSKEIESLKVSI 2616
Cdd:PHA02562  157 EDLldISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKTIKAEI 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2617 SQLTRQVTALQEEGtlGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVC------------VQKEAAKKVGEIEDK 2684
Cdd:PHA02562  237 EELTDELLNLVMDI--EDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCptctqqisegpdRITKIKDKLKELQHS 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2685 LKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQsfgrsmsSLQNSRDHANEELDELKR 2764
Cdd:PHA02562  315 LEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQD 386

                         250
                  ....*....|....*
gi 374532817 2765 KYDASLKELAQLKEQ 2779
Cdd:PHA02562  387 ELDKIVKTKSELVKE 401
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
816-1219 6.18e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 6.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  816 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELS--QALSQKELEITKMDQLLLEKKRD 893
Cdd:PRK03918  232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELRE 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  894 VETLQQTIEEKDQQVTEisfsmteKMVQLNEEKfslgVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSP 973
Cdd:PRK03918  312 IEKRLSRLEEEINGIEE-------RIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKR 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  974 AGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKdESKKEIPLSETERGEVEEDKENKEYse 1053
Cdd:PRK03918  381 LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK-KAKGKCPVCGRELTEEHRKELLEEY-- 457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1054 kcvTSKCQEIEIYLKqTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQ--TLQDKTNQIDL--LQAEISENQAIIQK 1129
Cdd:PRK03918  458 ---TAELKRIEKELK-EIEEKERKLRKELRELEKVLKKESELIKLKELAEQlkELEEKLKKYNLeeLEKKAEEYEKLKEK 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1130 LITSntdasDGDSVALVKETvvisppctgssehwkpeleEKILALEKEKEQLQKKLQEALTSRKAILKKAQEK----ERH 1205
Cdd:PRK03918  534 LIKL-----KGEIKSLKKEL-------------------EKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEE 589

                         410
                  ....*....|....
gi 374532817 1206 LREELKQQKDDYNR 1219
Cdd:PRK03918  590 LEERLKELEPFYNE 603
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2225-2985 6.45e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.34  E-value: 6.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2225 QSKEEEIRLKEDNCSVLKDQLRQMsihmEELKINISRLEHDKQIWESkaqTEVQLQQKVCDTLQGENKELLSQLEETRHL 2304
Cdd:TIGR00606  234 ESSREIVKSYENELDPLKNRLKEI----EHNLSKIMKLDNEIKALKS---RKKQMEKDNSELELKMEKVFQGTDEQLNDL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2305 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEgiIRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEEINM 2384
Cdd:TIGR00606  307 YHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL--VEQGRLQLQADRHQEHIRARDSLI---QSLATRLELDG 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2385 KEQKIISllsgkEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL 2464
Cdd:TIGR00606  382 FERGPFS-----ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2465 DSFVKSMSSLQNDRDRIVGDYQQL--EERHLSIiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE----- 2537
Cdd:TIGR00606  457 KFVIKELQQLEGSSDRILELDQELrkAERELSK-AEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtttrt 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2538 ----LIQYREDLNQVITIKDSQQKQLLEVQL---QQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIE 2610
Cdd:TIGR00606  536 qmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2611 SLKVSISQLTRQV----TALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKeAAKKVGEIEDKLK 2686
Cdd:TIGR00606  616 SKEEQLSSYEDKLfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCP-VCQRVFQTEAELQ 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2687 KELKHLHHDAGIMRNETETAEERVAELARD------LVEMEQKLL-MVTKENKGLTAQIQSFGRSMSSLQNSRDHANEEL 2759
Cdd:TIGR00606  695 EFISDLQSKLRLAPDKLKSTESELKKKEKRrdemlgLAPGRQSIIdLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2760 D------ELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEEnslshLEKLNQQLLSKDEQLLHLSSQLEDSY 2833
Cdd:TIGR00606  775 GtimpeeESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRT-----VQQVNQEKQEKQHELDTVVSKIELNR 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2834 NQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ-I 2912
Cdd:TIGR00606  850 KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEElI 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2913 NQEITELHPLKAQLQEYQDKTKA--------FQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQ 2984
Cdd:TIGR00606  930 SSKETSNKKAQDKVNDIKEKVKNihgymkdiENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDT 1009


                   .
gi 374532817  2985 Q 2985
Cdd:TIGR00606 1010 Q 1010
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 836-1050 6.66e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 6.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  836 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM 915
Cdd:COG3883    16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  916 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNydemspagQISKEELQHEFDLLKKENE 994
Cdd:COG3883    96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKADKAELEAK--------KAELEAKLAELEALKAELE 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 374532817  995 QRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1050
Cdd:COG3883   168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1063-1242 6.76e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 6.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1063 IEIYLKQTISEK-----------EVELQHIRKDLEEKLAAEEQFQA---------LVKQMNQTLQDKTNQIDLLQAEISE 1122
Cdd:COG3206   158 AEAYLEQNLELRreearkaleflEEQLPELRKELEEAEAALEEFRQknglvdlseEAKLLLQQLSELESQLAEARAELAE 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1123 NQAIIQKLitSNTDASDGDSVALVKETVVISppctgssehwkpELEEKILALEKEKEQ--------------LQKKLQEA 1188
Cdd:COG3206   238 AEARLAAL--RAQLGSGPDALPELLQSPVIQ------------QLRAQLAELEAELAElsarytpnhpdviaLRAQIAAL 303

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 374532817 1189 LTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1242
Cdd:COG3206   304 RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2042-2211 7.07e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 41.52  E-value: 7.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2042 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2117
Cdd:NF033928   88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2118 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2174
Cdd:NF033928  165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 374532817 2175 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2211
Cdd:NF033928  245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 699-1413 7.38e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.35  E-value: 7.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   699 LELELNFHKAQEIYEKnLDEKAKEISNLNQLIEEFKKNADNNSSAFTA----LSEERDQLLSQVKElSMVTELRAQVKQL 774
Cdd:TIGR01612 1005 LKANLGKNKENMLYHQ-FDEKEKATNDIEQKIEDANKNIPNIEIAIHTsiynIIDEIEKEIGKNIE-LLNKEILEEAEIN 1082

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   775 EMNLAE-AERQRRLDYESQTAHDNL-LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV 852
Cdd:TIGR01612 1083 ITNFNEiKEKLKHYNFDDFGKEENIkYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA 1162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   853 LEGaERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRdVETLQQTIEEkdqqVTEISFSMTEKM-----VQLNEEKF 927
Cdd:TIGR01612 1163 ISN-DDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAE-IEKDKTSLEE----VKGINLSYGKNLgklflEKIDEEKK 1236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   928 SLGVEIKTLKEQLNLLsraEEAKKEQVEEDNEVSSGLKQNyDEMSPAgQISKEELQHEFDLLKKENEQRKRKLQAALinr 1007
Cdd:TIGR01612 1237 KSEHMIKAMEAYIEDL---DEIKEKSPEIENEMGIEMDIK-AEMETF-NISHDDDKDHHIISKKHDENISDIREKSL--- 1308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1008 kELLQRVSRlEEELANLKDESKKEIplsetergeVEEDKENkeysekcvtskcQEIEIYLKQTISEKEV-ELQHIRKDLE 1086
Cdd:TIGR01612 1309 -KIIEDFSE-ESDINDIKKELQKNL---------LDAQKHN------------SDINLYLNEIANIYNIlKLNKIKKIID 1365

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1087 EKlaaeEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAI--IQKLITSNTDASDGDSV---ALVKETVVISPPcTGSSE 1161
Cdd:TIGR01612 1366 EV----KEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLeeCKSKIESTLDDKDIDECikkIKELKNHILSEE-SNIDT 1440

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1162 HWK--PELEEKILALEKEKEQLQKKLQEALTSRKailKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLR 1239
Cdd:TIGR01612 1441 YFKnaDENNENVLLLFKNIEMADNKSQHILKIKK---DNATNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFE 1517

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1240 QLQIQVRESIDgKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLES-------NLCPDWPSHSEDASALQGGTSVAQI 1312
Cdd:TIGR01612 1518 QYKKDVTELLN-KYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAekseqkiKEIKKEKFRIEDDAAKNDKSNKAAI 1596

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1313 KAQLKEIEAEKVELELkvssttSELTKKSEEVFQLQEQINKQ--GLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE 1390
Cdd:TIGR01612 1597 DIQLSLENFENKFLKI------SDIKKKINDCLKETESIEKKisSFSIDSQDTELKENGDNLNSLQEFLESLKDQKKNIE 1670

                          730       740
                   ....*....|....*....|...
gi 374532817  1391 hlrELQPKLDELQKLISKKEEDV 1413
Cdd:TIGR01612 1671 ---DKKKELDELDSEIEKIEIDV 1690
46 PHA02562
endonuclease subunit; Provisional
 2436-2681 7.51e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 7.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2436 NKKAVDKTNQLMETLkTIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2515
Cdd:PHA02562  172 NKDKIRELNQQIQTL-DMKIDHIQQ--QIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVM 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2516 EIRGLRSHMDDLNSENAKLDAELIQYREDlnqvitIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSF 2595
Cdd:PHA02562  249 DIEDPSAALNKLNTAAAKIKSKIEQFQKV------IKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAI 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2596 NALQE---EKQDLSKEIESLKVSISQLTRQVTAlqeegtlglYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK 2672
Cdd:PHA02562  323 DELEEimdEFNEQSKKLLELKNKISTNKQSLIT---------LVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVK 393


                  ....*....
gi 374532817 2673 EAAKKVGEI 2681
Cdd:PHA02562  394 TKSELVKEK 402
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 165-513 7.72e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 7.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  165 AQLTQAQA--EQPAQSSTEMEEFVMMKQQLQEKeefISTLQAQLSQTQAEQAAQlssmQQVVREKD---ARFETQVRLHE 239
Cdd:COG3096   316 EELSARESdlEQDYQAASDHLNLVQTALRQQEK---IERYQEDLEELTERLEEQ----EEVVEEAAeqlAEAEARLEAAE 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  240 DELLQLVTQ-ADVetemQQKLRVLQRKLEEHEESL--VGRAQVV-DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTV 315
Cdd:COG3096   389 EEVDSLKSQlADY----QQALDVQQTRAIQYQQAVqaLEKARALcGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKL 464

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  316 E------TEREESKILLEKMELEVaERKLSFHNLQE------EMHHLLEQFEQAGQAQAELESRysaLEQKHKA-----E 378
Cdd:COG3096   465 SvadaarRQFEKAYELVCKIAGEV-ERSQAWQTAREllrryrSQQALAQRLQQLRAQLAELEQR---LRQQQNAerlleE 540

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  379 MEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSK------EISQFLNRLPLQQHE 452
Cdd:COG3096   541 FCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAArapawlAAQDALERLREQSGE 620

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 374532817  453 TAsqtsfpdvynEGTQAVTEEniaslqkRVVELENEKGAlllsSIELEELKAENEKLSSQI 513
Cdd:COG3096   621 AL----------ADSQEVTAA-------MQQLLEREREA----TVERDELAARKQALESQI 660
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 247-926 7.77e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.34  E-value: 7.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   247 TQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNtlrntvetereesKILL 326
Cdd:TIGR00606  409 TAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSD-------------RILE 475

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   327 EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQkhkaEMEEKTSHILSLQKTGQELQSACDA---L 403
Cdd:TIGR00606  476 LDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQ----EMEQLNHHTTTRTQMEMLTKDKMDKdeqI 551

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   404 KDQNSKLLQDKNEQAVQSAQTiQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEE---------N 474
Cdd:TIGR00606  552 RKIKSRHSDELTSLLGYFPNK-KQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQlssyedklfD 630

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   475 IASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQN--------RTGEADREVSEIsIVDIANKRSSSAE 546
Cdd:TIGR00606  631 VCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENqsccpvcqRVFQTEAELQEF-ISDLQSKLRLAPD 709

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   547 EsgQDVLENTFSQKHKELSVLLL-------EMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVF 619
Cdd:TIGR00606  710 K--LKSTESELKKKEKRRDEMLGlapgrqsIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVC 787

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   620 LEDTGqdfpLMPNEESSLPAVEKEqasTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIG--------------Q 685
Cdd:TIGR00606  788 LTDVT----IMERFQMELKDVERK---IAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIelnrkliqdqqeqiQ 860

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   686 CHQDELERLKSQILELELNFHKAQEiYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVT 765
Cdd:TIGR00606  861 HLKSKTNELKSEKLQIGTNLQRRQQ-FEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKA 939

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   766 ELRAQ---------------------------VKQLEMNLA-----------------EAERQRRLDYESQTAHDNLLTE 801
Cdd:TIGR00606  940 QDKVNdikekvknihgymkdienkiqdgkddyLKQKETELNtvnaqleecekhqekinEDMRLMRQDIDTQKIQERWLQD 1019

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817   802 QIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIT 881
Cdd:TIGR00606 1020 NLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDA 1099

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 374532817   882 KmdqlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEK 926
Cdd:TIGR00606 1100 E------EKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMK 1138
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1845-1998 8.11e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.68  E-value: 8.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1845 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKE------ 1918
Cdd:COG1579    17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 1919 ---TAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1995
Cdd:COG1579    97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                  ...
gi 374532817 1996 LEK 1998
Cdd:COG1579   177 LAL 179
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1852-2388 8.21e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 8.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1852 ERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERL 1931
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  1932 MNQLAELNGsignycqdvtdAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSH 2011
Cdd:pfam01576   85 EEEEERSQQ-----------LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2012 AKELQEL-------LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAS 2084
Cdd:pfam01576  154 RKLLEERiseftsnLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAE 233

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2085 FKVLLDDTQSEAARVLA---DNLKLKKELQSNKESVKSQMKQKDEDLERRlEQAEEKHLKEKKNMQEKLDALRREKVHLE 2161
Cdd:pfam01576  234 LRAQLAKKEEELQAALArleEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEALKTELEDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2162 ETIGEIQVTLNKKDKEVQQLQENLDSTV----TQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEE-------E 2230
Cdd:pfam01576  313 DTTAAQQELRSKREQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenaelqaE 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2231 IRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWE---SKAQTEVQ-------LQQKVCDTLQGENKELLSQLEE 2300
Cdd:pfam01576  393 LRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAeklSKLQSELEsvssllnEAEGKNIKLSKDVSSLESQLQD 472

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  2301 TRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE 2380
Cdd:pfam01576  473 TQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQR 552


                   ....*...
gi 374532817  2381 EINMKEQK 2388
Cdd:pfam01576  553 ELEALTQQ 560
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
152-586 8.85e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 8.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  152 KLQEKEELISTLQAQLTQAQAEQPAQSSTEmEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQA-----AQLSSMQQVVRE 226
Cdd:COG4717    72 ELKELEEELKEAEEKEEEYAELQEELEELE-EELEELEAELEELREELEKLEKLLQLLPLYQElealeAELAELPERLEE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  227 KDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVD----LLQQELTAAEQRNQILSQQLQ 302
Cdd:COG4717   151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQqrlaELEEELEEAQEELEELEEELE 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  303 QMEAEHntlrntvETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEK 382
Cdd:COG4717   231 QLENEL-------EAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKE 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  383 TSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQflnrLPLQQHETASQTSFpdv 462
Cdd:COG4717   304 AEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE----LQLEELEQEIAALL--- 376

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  463 ynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEIS--IVDIANK 540
Cdd:COG4717   377 --AEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEeeLEELREE 454

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 374532817  541 RSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQ 586
Cdd:COG4717   455 LAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALE 500
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2476-2762 8.97e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 8.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2476 NDRDRIVGDY-------QQLEErhlsiileKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdAELIQYREDLNQV 2548
Cdd:COG4913   593 DDRRRIRSRYvlgfdnrAKLAA--------LEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV 663

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2549 itikDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2626
Cdd:COG4913   664 ----ASAEREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817 2627 QEEGTLGLyHAQLkvkeeEVHRLSALFSSSQKRIAE-LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET 2705
Cdd:COG4913   740 EDLARLEL-RALL-----EERFAAALGDAVERELREnLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLES 813

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 374532817 2706 AEERVAELAR----DLVEMEQKLLMVTKENkgltaQIQSFGRSMSSLQNSRDHANEELDEL 2762
Cdd:COG4913   814 LPEYLALLDRleedGLPEYEERFKELLNEN-----SIEFVADLLSKLRRAIREIKERIDPL 869
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
816-1006 9.59e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 9.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  816 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN--KESEVLEGAERVRHISSKVEELSQALSQKELEITKmdqlLLEKKRD 893
Cdd:COG4913   611 KLAALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  894 VETLQQTIEEKDQQVTEisfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEE-DNEVSSGLKQNYDEMS 972
Cdd:COG4913   687 LAALEEQLEELEAELEE-----------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLARLELRALLEERF 755

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 374532817  973 PAGQISK--EELQHEFDLLKKENEQRKRKLQAALIN 1006
Cdd:COG4913   756 AAALGDAveRELRENLEERIDALRARLNRAEEELER 791
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 248-358 9.98e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.86  E-value: 9.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374532817  248 QADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLR-NTVETEREeskill 326
Cdd:PRK11448  140 PENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQeKAAETSQE------ 213

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 374532817  327 EKMEL-EVAERKLSFHNLQEEMHHLL--EQFEQAG 358
Cdd:PRK11448  214 RKQKRkEITDQAAKRLELSEEETRILidQQLRKAG 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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