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Conserved domains on  [gi|359807067|ref|NP_001240845|]
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seizure 6-like protein isoform 1 precursor [Mus musculus]

Protein Classification

CUB domain-containing protein; beta-2-glycoprotein 1( domain architecture ID 12870547)

CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein| beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 568-676 1.91e-25

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 101.72  E-value: 1.91e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 568 CGGELSA-VAGVVLSPNWPEPYAEGEDCVWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYDGDEVVPHVLGQYFGHS 641
Cdd:cd00041    1 CGGTLTAsTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 359807067 642 SPQKLYSSTPDLTIQFHSDPAglifGKGQGFIMNY 676
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSS----VTGRGFKATY 111
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 392-501 2.01e-13

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 67.44  E-value: 2.01e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 392 CGGAVHNATIGRVLSPSFPGTANGSQLCVWTIEAPEGQK-----LHLHLERLLLHEKDRMIVYSGRTNTSALLyDSLRTE 466
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRirltfEDFDLESSPNCSYDYLEIYDGPSTSSPLL-GRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 359807067 467 SVPFEgLLSEGSSIRIEFTSDQGQAASAFNIRFEA 501
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 685-741 2.74e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 65.18  E-value: 2.74e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 359807067 685 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 741
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 685-870 3.51e-13

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 70.84  E-value: 3.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 685 CSDLPEIQNGWKTTSHTELvrGARITYQCDPGYDIVGSDTLTCQW----DLSWSSDPPFCEKIMyCTDPGEVEHSTRLIS 760
Cdd:PHA02927  86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESVK-CQSPPSISNGRHNGY 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 761 DPVLLVGTTIQYTCSPGFVLEGSSLLTCYSRETGTPiwtsrlPHCvseESLACDNPGLpENGY-QILYKRLYLPGESLTF 839
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP------PTC---QIVKCPHPTI-SNGYlSSGFKRSYSYNDNVDF 232

                        170       180       190
                 ....*....|....*....|....*....|.
gi 359807067 840 MCYEGFELMGEVTIRCILGqpSHWSGPLPIC 870
Cdd:PHA02927 233 KCKYGYKLSGSSSSTCSPG--NTWQPELPKC 261
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 221-328 1.26e-10

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 59.35  E-value: 1.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 221 CGVSFSDP-EGYIDSSDFPpQPYSSFLECTYNVTVYTGYGVELQVKSVNLSEGEL-----LSIRGVDGPTLTVLANQTLL 294
Cdd:cd00041    1 CGGTLTAStSGTISSPNYP-NNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....
gi 359807067 295 VEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA 328
Cdd:cd00041   80 TLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
Sushi pfam00084
Sushi repeat (SCR repeat);
507-564 3.20e-09

Sushi repeat (SCR repeat);


:

Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.66  E-value: 3.20e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 359807067  507 CYEP-YIQNGNFTTSDPTYNIGTIVEFTCDPGHSLeQGPAVIECVNvrDPYWNDTEPLC 564
Cdd:pfam00084   1 CPPPpDIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 333-388 6.53e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 6.53e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 359807067   333 CPFPRRPDAGEVTVM--DLHSGGVAHFHCHLGYELQGAKTLTCINASKphWSSQEPVC 388
Cdd:smart00032   1 CPPPPDIENGTVTSSsgTYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 2-186 1.82e-07

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.71  E-value: 1.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067    2 PVARPQAAGPDRISLFLVAFLLGS-PAAAQAEDGGPEGEMHPSTAYLLPSASLESSLEEGVTSAAPGLLPSQEaleameE 80
Cdd:PHA03247 2771 PPAAPAAGPPRRLTRPAVASLSESrESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP------G 2844

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   81 SLPPALPDEASVQHTPALRK--------GLPSLKQLNSARRQLRPLATPTTlQRLGSPASATTKLREPEDPEQPTAPAPL 152
Cdd:PHA03247 2845 PPPPSLPLGGSVAPGGDVRRrppsrspaAKPAAPARPPVRRLARPAVSRST-ESFALPPDQPERPPQPQAPPPPQPQPQP 2923

                         170       180       190
                  ....*....|....*....|....*....|....
gi 359807067  153 QIAPFTALATTLPHSPQPAQAPDDSSPGSPLDKG 186
Cdd:PHA03247 2924 PPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 568-676 1.91e-25

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 101.72  E-value: 1.91e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 568 CGGELSA-VAGVVLSPNWPEPYAEGEDCVWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYDGDEVVPHVLGQYFGHS 641
Cdd:cd00041    1 CGGTLTAsTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 359807067 642 SPQKLYSSTPDLTIQFHSDPAglifGKGQGFIMNY 676
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSS----VTGRGFKATY 111
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 577-676 2.81e-19

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 83.59  E-value: 2.81e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   577 GVVLSPNWPEPYAEGEDCVWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYDGDEVVPHVLGQYFGHSSPQKLYSS-T 650
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSsS 80

                           90       100
                   ....*....|....*....|....*.
gi 359807067   651 PDLTIQFHSDPAglifGKGQGFIMNY 676
Cdd:smart00042  81 NSLTLTFVSDSS----VQKRGFSARY 102
CUB pfam00431
CUB domain;
568-663 3.60e-17

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 78.11  E-value: 3.60e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067  568 CGGELSAVAGVVLSPNWPEPYAEGEDCVWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYDGDEVVPHVLGQYFGHSS 642
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHdecgyDYVEIRDGPSASSPLLGRFCGSGI 80

                          90       100
                  ....*....|....*....|.
gi 359807067  643 PQKLYSSTPDLTIQFHSDPAG 663
Cdd:pfam00431  81 PEDIVSSSNQMTIKFVSDASV 101
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 392-501 2.01e-13

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 67.44  E-value: 2.01e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 392 CGGAVHNATIGRVLSPSFPGTANGSQLCVWTIEAPEGQK-----LHLHLERLLLHEKDRMIVYSGRTNTSALLyDSLRTE 466
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRirltfEDFDLESSPNCSYDYLEIYDGPSTSSPLL-GRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 359807067 467 SVPFEgLLSEGSSIRIEFTSDQGQAASAFNIRFEA 501
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 685-741 2.74e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 65.18  E-value: 2.74e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 359807067 685 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 741
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 685-740 3.30e-13

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 64.86  E-value: 3.30e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 359807067   685 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 740
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 685-870 3.51e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 70.84  E-value: 3.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 685 CSDLPEIQNGWKTTSHTELvrGARITYQCDPGYDIVGSDTLTCQW----DLSWSSDPPFCEKIMyCTDPGEVEHSTRLIS 760
Cdd:PHA02927  86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESVK-CQSPPSISNGRHNGY 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 761 DPVLLVGTTIQYTCSPGFVLEGSSLLTCYSRETGTPiwtsrlPHCvseESLACDNPGLpENGY-QILYKRLYLPGESLTF 839
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP------PTC---QIVKCPHPTI-SNGYlSSGFKRSYSYNDNVDF 232

                        170       180       190
                 ....*....|....*....|....*....|.
gi 359807067 840 MCYEGFELMGEVTIRCILGqpSHWSGPLPIC 870
Cdd:PHA02927 233 KCKYGYKLSGSSSSTCSPG--NTWQPELPKC 261
Sushi pfam00084
Sushi repeat (SCR repeat);
685-740 3.50e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 62.13  E-value: 3.50e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 359807067  685 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 740
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 813-871 4.19e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 61.71  E-value: 4.19e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 359807067 813 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGqpSHWSGPLPICK 871
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN--GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 813-870 2.65e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.46  E-value: 2.65e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 359807067   813 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGqpSHWSGPLPIC 870
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN--GTWSPPPPTC 56
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 221-328 1.26e-10

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 59.35  E-value: 1.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 221 CGVSFSDP-EGYIDSSDFPpQPYSSFLECTYNVTVYTGYGVELQVKSVNLSEGEL-----LSIRGVDGPTLTVLANQTLL 294
Cdd:cd00041    1 CGGTLTAStSGTISSPNYP-NNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....
gi 359807067 295 VEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA 328
Cdd:cd00041   80 TLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
Sushi pfam00084
Sushi repeat (SCR repeat);
507-564 3.20e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.66  E-value: 3.20e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 359807067  507 CYEP-YIQNGNFTTSDPTYNIGTIVEFTCDPGHSLeQGPAVIECVNvrDPYWNDTEPLC 564
Cdd:pfam00084   1 CPPPpDIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 402-499 1.76e-08

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 53.16  E-value: 1.76e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   402 GRVLSPSFPGTANGSQLCVWTIEAPEGQK-----LHLHLERLLLHEKDRMIVYSGRTNTSALLYDSLRTESvPFEGLLSE 476
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRielqfTDFDLESSDNCEYDYVEIYDGPSASSPLLGRFCGSEA-PPPVISSS 79

                           90       100
                   ....*....|....*....|...
gi 359807067   477 GSSIRIEFTSDQGQAASAFNIRF 499
Cdd:smart00042  80 SNSLTLTFVSDSSVQKRGFSARY 102
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 510-564 3.59e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.60  E-value: 3.59e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 359807067   510 PYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLeQGPAVIECVNvrDPYWNDTEPLC 564
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITCLE--NGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 333-388 6.53e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 6.53e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 359807067   333 CPFPRRPDAGEVTVM--DLHSGGVAHFHCHLGYELQGAKTLTCINASKphWSSQEPVC 388
Cdd:smart00032   1 CPPPPDIENGTVTSSsgTYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 507-565 8.95e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.38  E-value: 8.95e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 359807067 507 CYEPY-IQNGNFTTSDPTYNIGTIVEFTCDPGHSLeQGPAVIECV-NVRdpyWNDTEPLCR 565
Cdd:cd00033    1 CPPPPvPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCTeNGG---WSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 333-388 1.55e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.00  E-value: 1.55e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 359807067 333 CPFPRRPDAGEVTVM--DLHSGGVAHFHCHLGYELQGAKTLTCInaSKPHWSSQEPVC 388
Cdd:cd00033    1 CPPPPVPENGTVTGSkgSYSYGSTVTYSCNEGYTLVGSSTITCT--ENGGWSPPPPTC 56
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2-186 1.82e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.71  E-value: 1.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067    2 PVARPQAAGPDRISLFLVAFLLGS-PAAAQAEDGGPEGEMHPSTAYLLPSASLESSLEEGVTSAAPGLLPSQEaleameE 80
Cdd:PHA03247 2771 PPAAPAAGPPRRLTRPAVASLSESrESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP------G 2844

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   81 SLPPALPDEASVQHTPALRK--------GLPSLKQLNSARRQLRPLATPTTlQRLGSPASATTKLREPEDPEQPTAPAPL 152
Cdd:PHA03247 2845 PPPPSLPLGGSVAPGGDVRRrppsrspaAKPAAPARPPVRRLARPAVSRST-ESFALPPDQPERPPQPQAPPPPQPQPQP 2923

                         170       180       190
                  ....*....|....*....|....*....|....
gi 359807067  153 QIAPFTALATTLPHSPQPAQAPDDSSPGSPLDKG 186
Cdd:PHA03247 2924 PPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957
Sushi pfam00084
Sushi repeat (SCR repeat);
813-870 2.40e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 2.40e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 359807067  813 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL-GQpshWSGPLPIC 870
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGT---WSPPFPEC 56
CUB pfam00431
CUB domain;
392-499 3.14e-07

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 49.60  E-value: 3.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067  392 CGGAVHNATiGRVLSPSFPGTANGSQLCVWTIEAPEGQK-----LHLHLERLLLHEKDRMIVYSGRTNTSALL--Ydslr 464
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRvkltfQDFELEDHDECGYDYVEIRDGPSASSPLLgrF---- 75

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 359807067  465 TESVPFEGLLSEGSSIRIEFTSDQGQAASAFNIRF 499
Cdd:pfam00431  76 CGSGIPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 230-326 1.06e-05

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 45.07  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   230 GYIDSSDFPpQPYSSFLECTYNVTVYTGYGVELQVKSVNLSEGEL-----LSIRgvDGPTLTVLANQTL---LVEGQVIR 301
Cdd:smart00042   1 GTITSPNYP-QSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDNceydyVEIY--DGPSASSPLLGRFcgsEAPPPVIS 77

                           90       100
                   ....*....|....*....|....*
gi 359807067   302 SPTNTISVYFRTFQDDGLGTFQLHY 326
Cdd:smart00042  78 SSSNSLTLTFVSDSSVQKRGFSARY 102
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 54-303 2.58e-05

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 48.35  E-value: 2.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067    54 ESSLEEGVTSAAPGLLPSQEALeameesLPPALPdeasvqhTPAlrkglPSLKQL-NSARRQLRPLATPTTLQRLGSPAS 132
Cdd:pfam15324  962 EAQREPPVAASVPGDLPTKETL------LPTPVP-------TPQ-----PTPPCSpPSPLKEPSPVKTPDSSPCVSEHDF 1023

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   133 ATTKLREPEDPEQPTAPAPLQIAPFTALATT-----LPHSPQPAQAPDD---SSPGSPLDKGDNELtgSASEES----QE 200
Cdd:pfam15324 1024 FPVKEIPPEKGADTGPAVSLVITPTVTPIATpppaaTPTPPLSENSIDKlksPSPELPKPWEDSDL--PLEEENpnseQE 1101

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   201 TTTSTIVTTTIITTEQAPALcgVSFSDPEGYIDSSDFP-----------PQPYSSFLECTYNVTVytgygVELQVKSVNL 269
Cdd:pfam15324 1102 ELHPRAVVMSVARDEEPESV--VLPASPPEPKPLAPPPlgaappsppqsPSSSSSTLESSSSLTV-----TETETADRPI 1174

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 359807067   270 SEGELL-------SIR-----GVDGPTLTVLANQTLL----------VEGQVIRSP 303
Cdd:pfam15324 1175 SEGEILfsygqmlAVRaleegGLFLPNLNDSLSSSLHdaqemdydppSEGQVIRRP 1230
Sushi pfam00084
Sushi repeat (SCR repeat);
333-388 1.55e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 40.56  E-value: 1.55e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 359807067  333 CPFPRRPDAGEVTV-MDLHS-GGVAHFHCHLGYELQGAKTLTCINASKphWSSQEPVC 388
Cdd:pfam00084   1 CPPPPDIPNGKVSAtKNEYNyGASVSYECDPGYRLVGSPTITCQEDGT--WSPPFPEC 56
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 1-187 2.30e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 41.76  E-value: 2.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   1 MPVARPQAAGPDRISLFLVAFLLGSPAAAQAEDGGPEGEmhPSTAYLLPSASLESSLEEGVTSAAPGLLPSQEALEAMEE 80
Cdd:COG3266  174 LQALGAVAALLGLRKAEEALALRAGSAAADALALLLLLL--ASALGEAVAAAAELAALALLAAGAAEVLTARLVLLLLII 251

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067  81 SLPPALPDEASVQHTPALRKGLPSLKQLNSARRQLRPLATPTTLQRLGSPASATTKLREPEDPEQPTAPAPLQIAPfTAL 160
Cdd:COG3266  252 GSALKAPSQASSASAPATTSLGEQQEVSLPPAVAAQPAAAAAAQPSAVALPAAPAAAAAAAAPAEAAAPQPTAAKP-VVT 330

                        170       180
                 ....*....|....*....|....*..
gi 359807067 161 ATTLPHSPQPAQAPDDSSPGSPLDKGD 187
Cdd:COG3266  331 ETAAPAAPAPEAAAAAAAPAAPAVAKK 357
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 568-676 1.91e-25

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 101.72  E-value: 1.91e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 568 CGGELSA-VAGVVLSPNWPEPYAEGEDCVWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYDGDEVVPHVLGQYFGHS 641
Cdd:cd00041    1 CGGTLTAsTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 359807067 642 SPQKLYSSTPDLTIQFHSDPAglifGKGQGFIMNY 676
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSS----VTGRGFKATY 111
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 577-676 2.81e-19

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 83.59  E-value: 2.81e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   577 GVVLSPNWPEPYAEGEDCVWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYDGDEVVPHVLGQYFGHSSPQKLYSS-T 650
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSsS 80

                           90       100
                   ....*....|....*....|....*.
gi 359807067   651 PDLTIQFHSDPAglifGKGQGFIMNY 676
Cdd:smart00042  81 NSLTLTFVSDSS----VQKRGFSARY 102
CUB pfam00431
CUB domain;
568-663 3.60e-17

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 78.11  E-value: 3.60e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067  568 CGGELSAVAGVVLSPNWPEPYAEGEDCVWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYDGDEVVPHVLGQYFGHSS 642
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHdecgyDYVEIRDGPSASSPLLGRFCGSGI 80

                          90       100
                  ....*....|....*....|.
gi 359807067  643 PQKLYSSTPDLTIQFHSDPAG 663
Cdd:pfam00431  81 PEDIVSSSNQMTIKFVSDASV 101
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 392-501 2.01e-13

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 67.44  E-value: 2.01e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 392 CGGAVHNATIGRVLSPSFPGTANGSQLCVWTIEAPEGQK-----LHLHLERLLLHEKDRMIVYSGRTNTSALLyDSLRTE 466
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRirltfEDFDLESSPNCSYDYLEIYDGPSTSSPLL-GRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 359807067 467 SVPFEgLLSEGSSIRIEFTSDQGQAASAFNIRFEA 501
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 685-741 2.74e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 65.18  E-value: 2.74e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 359807067 685 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 741
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 685-740 3.30e-13

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 64.86  E-value: 3.30e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 359807067   685 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 740
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 685-870 3.51e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 70.84  E-value: 3.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 685 CSDLPEIQNGWKTTSHTELvrGARITYQCDPGYDIVGSDTLTCQW----DLSWSSDPPFCEKIMyCTDPGEVEHSTRLIS 760
Cdd:PHA02927  86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESVK-CQSPPSISNGRHNGY 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 761 DPVLLVGTTIQYTCSPGFVLEGSSLLTCYSRETGTPiwtsrlPHCvseESLACDNPGLpENGY-QILYKRLYLPGESLTF 839
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP------PTC---QIVKCPHPTI-SNGYlSSGFKRSYSYNDNVDF 232

                        170       180       190
                 ....*....|....*....|....*....|.
gi 359807067 840 MCYEGFELMGEVTIRCILGqpSHWSGPLPIC 870
Cdd:PHA02927 233 KCKYGYKLSGSSSSTCSPG--NTWQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 684-872 1.35e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 68.91  E-value: 1.35e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 684 SCSDLP------EIQNGWKTTSHTELVRGARITYQCDPGY--DIVGSDTLTCQ---WDLswssdppFCEKIMY-CTDPGE 751
Cdd:PHA02927  19 SCCTIPsrpinmKFKNSVETDANANYNIGDTIEYLCLPGYrkQKMGPIYAKCTgtgWTL-------FNQCIKRrCPSPRD 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 752 VEHSTRLISDpvLLVGTTIQYTCSPGFVLEGSSLLTCYSRETGTPIWTSRLPHCvseESLACDNPGLPENGYQILYKRLY 831
Cdd:PHA02927  92 IDNGQLDIGG--VDFGSSITYSCNSGYQLIGESKSYCELGSTGSMVWNPEAPIC---ESVKCQSPPSISNGRHNGYEDFY 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 359807067 832 LPGESLTFMCYEGFELMGEVTIRCILGQpshWSGPlPICKV 872
Cdd:PHA02927 167 TDGSVVTYSCNSGYSLIGNSGVLCSGGE---WSDP-PTCQI 203
Sushi pfam00084
Sushi repeat (SCR repeat);
685-740 3.50e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 62.13  E-value: 3.50e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 359807067  685 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 740
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 813-871 4.19e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 61.71  E-value: 4.19e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 359807067 813 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGqpSHWSGPLPICK 871
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN--GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 813-870 2.65e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.46  E-value: 2.65e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 359807067   813 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGqpSHWSGPLPIC 870
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN--GTWSPPPPTC 56
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 221-328 1.26e-10

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 59.35  E-value: 1.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 221 CGVSFSDP-EGYIDSSDFPpQPYSSFLECTYNVTVYTGYGVELQVKSVNLSEGEL-----LSIRGVDGPTLTVLANQTLL 294
Cdd:cd00041    1 CGGTLTAStSGTISSPNYP-NNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....
gi 359807067 295 VEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA 328
Cdd:cd00041   80 TLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
PHA02639 PHA02639
EEV host range protein; Provisional
 676-874 4.84e-10

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 61.99  E-value: 4.84e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 676 YIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLS---WSSDPPFCeKIMYCTDPGEV 752
Cdd:PHA02639  13 YVHGVKSIYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNnaiWSNKAPFC-MLKECNDPPSI 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 753 EHSTRLISDPVLLVGTTIQYTCSP----GFVLEGSSLLTCYSRETgtpiWTSRLPHCvseESLACDNPGLpENGY--QIL 826
Cdd:PHA02639  92 INGKIYNKREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKS----WKPDPPIC---KMINCRFPAL-QNGYinGIP 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 359807067 827 YKRLYLPGESLTFMCYEGFELMGEVTIRCILGqpSHWSGPLPICKVNQ 874
Cdd:PHA02639 164 SNKKFYYKTRVGFSCKSGFDLVGEKYSTCNIN--ATWFPSIPTCVRNK 209
PHA02639 PHA02639
EEV host range protein; Provisional
 685-811 1.08e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 60.83  E-value: 1.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 685 CSDLPEIQNGwKTTSHTELVR-GARITYQCDP----GYDIVGSDTLTCQWDLSWSSDPPFCeKIMYCTDPG-EVEHSTRL 758
Cdd:PHA02639  85 CNDPPSIING-KIYNKREMYKvGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKPDPPIC-KMINCRFPAlQNGYINGI 162

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 359807067 759 ISDPVLLVGTTIQYTCSPGFVLEGSSLLTCYSRETgtpiWTSRLPHCVSEESL 811
Cdd:PHA02639 163 PSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINAT----WFPSIPTCVRNKPI 211
PHA02817 PHA02817
EEV Host range protein; Provisional
 683-806 1.84e-09

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 58.80  E-value: 1.84e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 683 DSCSDLPEIQNGWKTTSHTELVRGARITYQCDPG-----YDIVGSDTLTCQWDLSWSSDPPFCEkIMYCTDPG-EVEHST 756
Cdd:PHA02817  22 NKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCK-IIRCRFPAlQNGFVN 100

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 359807067 757 RLISDPVLLVGTTIQYTCSPGFVLEGSSLLTCYSRETgtpiWTSRLPHCV 806
Cdd:PHA02817 101 GIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSS----WIPKVPICS 146
Sushi pfam00084
Sushi repeat (SCR repeat);
507-564 3.20e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.66  E-value: 3.20e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 359807067  507 CYEP-YIQNGNFTTSDPTYNIGTIVEFTCDPGHSLeQGPAVIECVNvrDPYWNDTEPLC 564
Cdd:pfam00084   1 CPPPpDIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 685-806 5.50e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.13  E-value: 5.50e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 685 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC---QWdlswsSDPPFCEkIMYCTDPGevehstrlISD 761
Cdd:PHA02927 148 CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCsggEW-----SDPPTCQ-IVKCPHPT--------ISN 213

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 359807067 762 PVLLVG--------TTIQYTCSPGFVLEGSSLLTCYSRETgtpiWTSRLPHCV 806
Cdd:PHA02927 214 GYLSSGfkrsysynDNVDFKCKYGYKLSGSSSSTCSPGNT----WQPELPKCV 262
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 746-805 6.48e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.91  E-value: 6.48e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   746 CTDPGEVEHSTRLISDPVLLVGTTIQYTCSPGFVLEGSSLLTCysRETGTpiWTSRLPHC 805
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITC--LENGT--WSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 746-806 6.94e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.85  E-value: 6.94e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 359807067 746 CTDPGEVEHSTRLISDPVLLVGTTIQYTCSPGFVLEGSSLLTCysreTGTPIWTSRLPHCV 806
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITC----TENGGWSPPPPTCE 57
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 402-499 1.76e-08

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 53.16  E-value: 1.76e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   402 GRVLSPSFPGTANGSQLCVWTIEAPEGQK-----LHLHLERLLLHEKDRMIVYSGRTNTSALLYDSLRTESvPFEGLLSE 476
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRielqfTDFDLESSDNCEYDYVEIYDGPSASSPLLGRFCGSEA-PPPVISSS 79

                           90       100
                   ....*....|....*....|...
gi 359807067   477 GSSIRIEFTSDQGQAASAFNIRF 499
Cdd:smart00042  80 SNSLTLTFVSDSSVQKRGFSARY 102
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 510-564 3.59e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.60  E-value: 3.59e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 359807067   510 PYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLeQGPAVIECVNvrDPYWNDTEPLC 564
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITCLE--NGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 333-388 6.53e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 6.53e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 359807067   333 CPFPRRPDAGEVTVM--DLHSGGVAHFHCHLGYELQGAKTLTCINASKphWSSQEPVC 388
Cdd:smart00032   1 CPPPPDIENGTVTSSsgTYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 507-565 8.95e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.38  E-value: 8.95e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 359807067 507 CYEPY-IQNGNFTTSDPTYNIGTIVEFTCDPGHSLeQGPAVIECV-NVRdpyWNDTEPLCR 565
Cdd:cd00033    1 CPPPPvPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCTeNGG---WSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 333-388 1.55e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.00  E-value: 1.55e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 359807067 333 CPFPRRPDAGEVTVM--DLHSGGVAHFHCHLGYELQGAKTLTCInaSKPHWSSQEPVC 388
Cdd:cd00033    1 CPPPPVPENGTVTGSkgSYSYGSTVTYSCNEGYTLVGSSTITCT--ENGGWSPPPPTC 56
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2-186 1.82e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.71  E-value: 1.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067    2 PVARPQAAGPDRISLFLVAFLLGS-PAAAQAEDGGPEGEMHPSTAYLLPSASLESSLEEGVTSAAPGLLPSQEaleameE 80
Cdd:PHA03247 2771 PPAAPAAGPPRRLTRPAVASLSESrESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP------G 2844

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   81 SLPPALPDEASVQHTPALRK--------GLPSLKQLNSARRQLRPLATPTTlQRLGSPASATTKLREPEDPEQPTAPAPL 152
Cdd:PHA03247 2845 PPPPSLPLGGSVAPGGDVRRrppsrspaAKPAAPARPPVRRLARPAVSRST-ESFALPPDQPERPPQPQAPPPPQPQPQP 2923

                         170       180       190
                  ....*....|....*....|....*....|....
gi 359807067  153 QIAPFTALATTLPHSPQPAQAPDDSSPGSPLDKG 186
Cdd:PHA03247 2924 PPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957
Sushi pfam00084
Sushi repeat (SCR repeat);
813-870 2.40e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 2.40e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 359807067  813 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL-GQpshWSGPLPIC 870
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGT---WSPPFPEC 56
CUB pfam00431
CUB domain;
392-499 3.14e-07

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 49.60  E-value: 3.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067  392 CGGAVHNATiGRVLSPSFPGTANGSQLCVWTIEAPEGQK-----LHLHLERLLLHEKDRMIVYSGRTNTSALL--Ydslr 464
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRvkltfQDFELEDHDECGYDYVEIRDGPSASSPLLgrF---- 75

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 359807067  465 TESVPFEGLLSEGSSIRIEFTSDQGQAASAFNIRF 499
Cdd:pfam00431  76 CGSGIPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
Sushi pfam00084
Sushi repeat (SCR repeat);
746-805 8.43e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.72  E-value: 8.43e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067  746 CTDPGEVEHSTRLISDPVLLVGTTIQYTCSPGFVLEGSSLLTCysRETGTpiWTSRLPHC 805
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITC--QEDGT--WSPPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 706-806 4.67e-06

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 49.70  E-value: 4.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 706 GARITYQCDPGYDIVGSDTLTCQWDlSWSSDPPFCEKimyCTDPgevEHSTRLISDPVLLVGTTIQYTCSPGFVLEGSSL 785
Cdd:PHA02954 150 GEHITINCDVGYEVIGASYISCTAN-SWNVIPSCQQK---CDIP---SLSNGLISGSTFSIGGVIHLSCKSGFTLTGSPS 222

                         90       100
                 ....*....|....*....|.
gi 359807067 786 LTCYSREtgtpiWTSRLPHCV 806
Cdd:PHA02954 223 STCIDGK-----WNPVLPICV 238
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 230-326 1.06e-05

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 45.07  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   230 GYIDSSDFPpQPYSSFLECTYNVTVYTGYGVELQVKSVNLSEGEL-----LSIRgvDGPTLTVLANQTL---LVEGQVIR 301
Cdd:smart00042   1 GTITSPNYP-QSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDNceydyVEIY--DGPSASSPLLGRFcgsEAPPPVIS 77

                           90       100
                   ....*....|....*....|....*
gi 359807067   302 SPTNTISVYFRTFQDDGLGTFQLHY 326
Cdd:smart00042  78 SSSNSLTLTFVSDSSVQKRGFSARY 102
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 54-303 2.58e-05

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 48.35  E-value: 2.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067    54 ESSLEEGVTSAAPGLLPSQEALeameesLPPALPdeasvqhTPAlrkglPSLKQL-NSARRQLRPLATPTTLQRLGSPAS 132
Cdd:pfam15324  962 EAQREPPVAASVPGDLPTKETL------LPTPVP-------TPQ-----PTPPCSpPSPLKEPSPVKTPDSSPCVSEHDF 1023

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   133 ATTKLREPEDPEQPTAPAPLQIAPFTALATT-----LPHSPQPAQAPDD---SSPGSPLDKGDNELtgSASEES----QE 200
Cdd:pfam15324 1024 FPVKEIPPEKGADTGPAVSLVITPTVTPIATpppaaTPTPPLSENSIDKlksPSPELPKPWEDSDL--PLEEENpnseQE 1101

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   201 TTTSTIVTTTIITTEQAPALcgVSFSDPEGYIDSSDFP-----------PQPYSSFLECTYNVTVytgygVELQVKSVNL 269
Cdd:pfam15324 1102 ELHPRAVVMSVARDEEPESV--VLPASPPEPKPLAPPPlgaappsppqsPSSSSSTLESSSSLTV-----TETETADRPI 1174

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 359807067   270 SEGELL-------SIR-----GVDGPTLTVLANQTLL----------VEGQVIRSP 303
Cdd:pfam15324 1175 SEGEILfsygqmlAVRaleegGLFLPNLNDSLSSSLHdaqemdydppSEGQVIRRP 1230
PHA02831 PHA02831
EEV host range protein; Provisional
 708-870 9.54e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 45.37  E-value: 9.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 708 RITYQCDPGYDIVgsdTLTCQwDLSWSSDPpFCEKIMYCTDP-----GEVEHSTRLISdpvllVGTTIQYTCSPG----F 778
Cdd:PHA02831  45 NLEYKCNNNFDKV---FVTCN-NGSWSTKN-MCIGKRNCKDPvtilnGYIKNKKDQYS-----FGDSVTYACKVNklekY 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067 779 VLEGSSLLTCYSREtgtpiWTSRLPHCvseESLACDNPGLpENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCilG 858
Cdd:PHA02831 115 SIVGNETVKCINKQ-----WVPKYPVC---KLIRCKYPAL-QNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTC--D 183

                        170
                 ....*....|..
gi 359807067 859 QPSHWSGPLPIC 870
Cdd:PHA02831 184 INSIWYPGIPKC 195
Sushi pfam00084
Sushi repeat (SCR repeat);
333-388 1.55e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 40.56  E-value: 1.55e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 359807067  333 CPFPRRPDAGEVTV-MDLHS-GGVAHFHCHLGYELQGAKTLTCINASKphWSSQEPVC 388
Cdd:pfam00084   1 CPPPPDIPNGKVSAtKNEYNyGASVSYECDPGYRLVGSPTITCQEDGT--WSPPFPEC 56
PHA03247 PHA03247
large tegument protein UL36; Provisional
 26-194 1.33e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   26 PAAAQAEDGGPEGEMHPSTAYLLPSASLESSLE-------EGVTSAAPGLLPSQEALEAMEESLPPALPDEASVQHTPAL 98
Cdd:PHA03247 2554 PLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRArrpdappQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSP 2633

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   99 RKGLPSLKQLNSARRQLRPLATP-----TTLQRLGSPASATTKLREPEDPEQPTAPAPlqIAPFTALATTLPHSPQPAQA 173
Cdd:PHA03247 2634 AANEPDPHPPPTVPPPERPRDDPapgrvSRPRRARRLGRAAQASSPPQRPRRRAARPT--VGSLTSLADPPPPPPTPEPA 2711

                         170       180
                  ....*....|....*....|.
gi 359807067  174 PDDSSPGSPLDKGDNELTGSA 194
Cdd:PHA03247 2712 PHALVSATPLPPGPAAARQAS 2732
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 1-187 2.30e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 41.76  E-value: 2.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   1 MPVARPQAAGPDRISLFLVAFLLGSPAAAQAEDGGPEGEmhPSTAYLLPSASLESSLEEGVTSAAPGLLPSQEALEAMEE 80
Cdd:COG3266  174 LQALGAVAALLGLRKAEEALALRAGSAAADALALLLLLL--ASALGEAVAAAAELAALALLAAGAAEVLTARLVLLLLII 251

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067  81 SLPPALPDEASVQHTPALRKGLPSLKQLNSARRQLRPLATPTTLQRLGSPASATTKLREPEDPEQPTAPAPLQIAPfTAL 160
Cdd:COG3266  252 GSALKAPSQASSASAPATTSLGEQQEVSLPPAVAAQPAAAAAAQPSAVALPAAPAAAAAAAAPAEAAAPQPTAAKP-VVT 330

                        170       180
                 ....*....|....*....|....*..
gi 359807067 161 ATTLPHSPQPAQAPDDSSPGSPLDKGD 187
Cdd:COG3266  331 ETAAPAAPAPEAAAAAAAPAAPAVAKK 357
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
34-182 4.44e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 4.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067  34 GGPEGEMHPSTAYLLPSASLESSLEEGVTSAAPGLLPSQEALEAMEESLPPALPDEASVQHTPAlRKGLPSLKQLNSARR 113
Cdd:PRK12323 366 GQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPA-PEALAAARQASARGP 444

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 359807067 114 QLRPLATPTtlqrlgsPASAttklrepedPEQPTAPAPLQIAPFTALATTLPHSPQPAQAPDDSSPGSP 182
Cdd:PRK12323 445 GGAPAPAPA-------PAAA---------PAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPP 497
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
4-195 4.80e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.99  E-value: 4.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067   4 ARPQAAGPDRISLFLVAflLGSPAAAQAEDGGPEGEMHPSTAYLLPSASLESSLEEGVTSAAPGLLPSQEALEAMeeSLP 83
Cdd:PRK07003 410 LAPKAAAAAAATRAEAP--PAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPAS--DAP 485

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359807067  84 PALPDEAS---VQHTPALRKGLPSLKQLNSARR--QLRPLATPTTLQRLGSPASATTK-----------------LREPE 141
Cdd:PRK07003 486 PDAAFEPApraAAPSAATPAAVPDARAPAAASRedAPAAAAPPAPEARPPTPAAAAPAaraggaaaaldvlrnagMRVSS 565

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 359807067 142 DPEQPTAPAPLQIAPftALATTLPHSPQPA-QAPddsSPGSPLDKGDNELTGSAS 195
Cdd:PRK07003 566 DRGARAAAAAKPAAA--PAAAPKPAAPRVAvQVP---TPRARAATGDAPPNGAAR 615
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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