NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|347921162|ref|NP_001231665|]
View 

CCHC-type zinc finger, nucleic acid binding protein a [Danio rerio]

Protein Classification

CCHC-type zinc finger protein( domain architecture ID 1000253)

CCHC-type zinc finger protein similar to human cellular nucleic acid-binding protein, a single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PTZ00368 super family cl31762
universal minicircle sequence binding protein (UMSBP); Provisional
 40-157 8.93e-27

universal minicircle sequence binding protein (UMSBP); Provisional


The actual alignment was detected with superfamily member PTZ00368:

Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 98.34  E-value: 8.93e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347921162  40 CYRCGEQGHIARDCEQTEDA-------CYNCHRSGHISRDC-KEPKKEREQCCYNCGKAGHVARDCDHA----NEQKCYS 107
Cdd:PTZ00368   3 CYRCGGVGHQSRECPNSAPAgaakarpCYKCGEPGHLSRECpSAPGGRGERSCYNCGKTGHLSRECPEAppgsGPRSCYN 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 347921162 108 CGGFGHIQKLC--------DKVKCYRCGEIGHVAVQCSKAT-----EVNCYNCGKTGHLARDC 157
Cdd:PTZ00368  83 CGQTGHISRECpnrakggaARRACYNCGGEGHISRDCPNAGkrpggDKTCYNCGQTGHLSRDC 145
COG5222 super family cl34947
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
8-22 1.25e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


The actual alignment was detected with superfamily member COG5222:

Pssm-ID: 227547 [Multi-domain]  Cd Length: 427  Bit Score: 38.19  E-value: 1.25e-03
                         10
                 ....*....|....*
gi 347921162   8 CFGCGRSGHWIKNCP 22
Cdd:COG5222  179 CYRCGQKGHWIQNCP 193
 
Name Accession Description Interval E-value
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 40-157 8.93e-27

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 98.34  E-value: 8.93e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347921162  40 CYRCGEQGHIARDCEQTEDA-------CYNCHRSGHISRDC-KEPKKEREQCCYNCGKAGHVARDCDHA----NEQKCYS 107
Cdd:PTZ00368   3 CYRCGGVGHQSRECPNSAPAgaakarpCYKCGEPGHLSRECpSAPGGRGERSCYNCGKTGHLSRECPEAppgsGPRSCYN 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 347921162 108 CGGFGHIQKLC--------DKVKCYRCGEIGHVAVQCSKAT-----EVNCYNCGKTGHLARDC 157
Cdd:PTZ00368  83 CGQTGHISRECpnrakggaARRACYNCGGEGHISRDCPNAGkrpggDKTCYNCGQTGHLSRDC 145
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 39-162 1.94e-20

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 82.98  E-value: 1.94e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347921162  39 FCYRCGEQGHIARDCeqTEDACYNCHRSGHISRDCKEPKKereqcCYNCGKAGHVARDCDHANEQK--CYSCGGFGHIQK 116
Cdd:COG5082   62 VCFNCGQNGHLRRDC--PHSICYNCSWDGHRSNHCPKPKK-----CYNCGETGHLSRDCNPSKDQQksCFDCNSTRHSSE 134

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 347921162 117 LCDKVKCYRCGEIGHVAVQcskatEVNCYNCGKTGHLARDCSIEAS 162
Cdd:COG5082  135 DCPSIWKHYVLNNGDGHPI-----KKFCYSCGSAGHFGDDCKEPRS 175
COG5222 COG5222
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
8-22 1.25e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227547 [Multi-domain]  Cd Length: 427  Bit Score: 38.19  E-value: 1.25e-03
                         10
                 ....*....|....*
gi 347921162   8 CFGCGRSGHWIKNCP 22
Cdd:COG5222  179 CYRCGQKGHWIQNCP 193
 
Name Accession Description Interval E-value
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 40-157 8.93e-27

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 98.34  E-value: 8.93e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347921162  40 CYRCGEQGHIARDCEQTEDA-------CYNCHRSGHISRDC-KEPKKEREQCCYNCGKAGHVARDCDHA----NEQKCYS 107
Cdd:PTZ00368   3 CYRCGGVGHQSRECPNSAPAgaakarpCYKCGEPGHLSRECpSAPGGRGERSCYNCGKTGHLSRECPEAppgsGPRSCYN 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 347921162 108 CGGFGHIQKLC--------DKVKCYRCGEIGHVAVQCSKAT-----EVNCYNCGKTGHLARDC 157
Cdd:PTZ00368  83 CGQTGHISRECpnrakggaARRACYNCGGEGHISRDCPNAGkrpggDKTCYNCGQTGHLSRDC 145
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 39-162 1.94e-20

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 82.98  E-value: 1.94e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347921162  39 FCYRCGEQGHIARDCeqTEDACYNCHRSGHISRDCKEPKKereqcCYNCGKAGHVARDCDHANEQK--CYSCGGFGHIQK 116
Cdd:COG5082   62 VCFNCGQNGHLRRDC--PHSICYNCSWDGHRSNHCPKPKK-----CYNCGETGHLSRDCNPSKDQQksCFDCNSTRHSSE 134

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 347921162 117 LCDKVKCYRCGEIGHVAVQcskatEVNCYNCGKTGHLARDCSIEAS 162
Cdd:COG5082  135 DCPSIWKHYVLNNGDGHPI-----KKFCYSCGSAGHFGDDCKEPRS 175
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 3-118 4.20e-19

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 78.70  E-value: 4.20e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347921162   3 MSTSECFGCGRSGHWIKNCPNAGRGRGrgrgrgkDLFCYRCGEQGHIARDCEQTED-----ACYNCHRSGHISRDCKEPK 77
Cdd:PTZ00368  25 AKARPCYKCGEPGHLSRECPSAPGGRG-------ERSCYNCGKTGHLSRECPEAPPgsgprSCYNCGQTGHISRECPNRA 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 347921162  78 K--EREQCCYNCGKAGHVARDCDHAN-----EQKCYSCGGFGHIQKLC 118
Cdd:PTZ00368  98 KggAARRACYNCGGEGHISRDCPNAGkrpggDKTCYNCGQTGHLSRDC 145
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 8-152 8.61e-15

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 68.34  E-value: 8.61e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347921162   8 CFGCGRSGHWIKNCPNAgrgrgrgrgrgkdlFCYRCGEQGHIARDCEQTEdACYNCHRSGHISRDCkEPKKEREQCCYNC 87
Cdd:COG5082   63 CFNCGQNGHLRRDCPHS--------------ICYNCSWDGHRSNHCPKPK-KCYNCGETGHLSRDC-NPSKDQQKSCFDC 126

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 347921162  88 GKAGHVARDCDHANEQKCYSCGGFGHIQKLcdkvkCYRCGEIGHVAVQCSKATEVNC-YNCGKTGH 152
Cdd:COG5082  127 NSTRHSSEDCPSIWKHYVLNNGDGHPIKKF-----CYSCGSAGHFGDDCKEPRSSRVpYVCGKKGY 187
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 69-157 9.90e-14

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 65.26  E-value: 9.90e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347921162  69 ISRDCKEPKKEREQCCYNCGKAGHVARDCDHAneqKCYSCGGFGHIQKLCDK-VKCYRCGEIGHVAVQC--SKATEVNCY 145
Cdd:COG5082   48 RSVEDVSAIREENPVCFNCGQNGHLRRDCPHS---ICYNCSWDGHRSNHCPKpKKCYNCGETGHLSRDCnpSKDQQKSCF 124

                         90
                 ....*....|..
gi 347921162 146 NCGKTGHLARDC 157
Cdd:COG5082  125 DCNSTRHSSEDC 136
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 102-158 1.47e-10

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 56.78  E-value: 1.47e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 347921162 102 EQKCYSCGGFGHIQKLCDKVKCYRCGEIGHVAVQCSKAteVNCYNCGKTGHLARDCS 158
Cdd:COG5082   60 NPVCFNCGQNGHLRRDCPHSICYNCSWDGHRSNHCPKP--KKCYNCGETGHLSRDCN 114
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 8-75 1.79e-09

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 53.27  E-value: 1.79e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 347921162   8 CFGCGRSGHWIKNCPNAGRGRGRGRGrgkdlfCYRCGEQGHIARDCEQTED------ACYNCHRSGHISRDCKE 75
Cdd:PTZ00368  80 CYNCGQTGHISRECPNRAKGGAARRA------CYNCGGEGHISRDCPNAGKrpggdkTCYNCGQTGHLSRDCPD 147
COG5222 COG5222
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
8-22 1.25e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227547 [Multi-domain]  Cd Length: 427  Bit Score: 38.19  E-value: 1.25e-03
                         10
                 ....*....|....*
gi 347921162   8 CFGCGRSGHWIKNCP 22
Cdd:COG5222  179 CYRCGQKGHWIQNCP 193
PRK14280 PRK14280
molecular chaperone DnaJ;
57-116 5.71e-03

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 36.24  E-value: 5.71e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 347921162  57 EDACYNCHRSGhisrdcKEPKKEREQCCYnCGKAGHVA-------------RDCDHAN------EQKCYSCGGFGHIQK 116
Cdd:PRK14280 143 EETCDTCHGSG------AKPGTSKETCSH-CGGSGQVSveqntpfgrvvnrQTCPHCNgtgqeiKEKCPTCHGKGKVRK 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH