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Conserved domains on  [gi|339276075|ref|NP_001229846|]
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AN1-type zinc finger protein 6 isoform b [Homo sapiens]

Protein Classification

zinc finger A20 and AN1 domain-containing stress-associated protein( domain architecture ID 10484704)

zinc finger A20 and AN1 domain-containing stress-associated protein similar to Homo sapiens AN1-type zinc finger protein that is involved in protein degradation via the ubiquitin-proteasome system

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_AN1 smart00154
AN1-like Zinc finger; Zinc finger at the C-terminus of An1, a ubiquitin-like protein in ...
 137-174 8.00e-12

AN1-like Zinc finger; Zinc finger at the C-terminus of An1, a ubiquitin-like protein in Xenopus laevis.


:

Pssm-ID: 197545  Cd Length: 39  Bit Score: 57.40  E-value: 8.00e-12
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 339276075   137 CFMCRKKVGLTGFECR-CGNVYCGVHRYSDVHNCSYNYK 174
Cdd:smart00154   1 CHFCRKKVGLTGFKCRhCGNLFCGEHRLPEDHDCPGDYK 39
zf-A20 pfam01754
A20-like zinc finger; The A20 Zn-finger of bovine/human Rabex5/rabGEF1 is a Ubiquitin Binding ...
 12-35 9.11e-09

A20-like zinc finger; The A20 Zn-finger of bovine/human Rabex5/rabGEF1 is a Ubiquitin Binding Domain. The zinc finger mediates self-association in A20. These fingers also mediate IL-1-induced NF-kappa B activation.


:

Pssm-ID: 460313  Cd Length: 24  Bit Score: 49.04  E-value: 9.11e-09
                          10        20
                  ....*....|....*....|....
gi 339276075   12 MLCSTGCGFYGNPRTNGMCSVCYK 35
Cdd:pfam01754   1 LLCRNGCGFYGSPATNGLCSKCYK 24
 
Name Accession Description Interval E-value
ZnF_AN1 smart00154
AN1-like Zinc finger; Zinc finger at the C-terminus of An1, a ubiquitin-like protein in ...
 137-174 8.00e-12

AN1-like Zinc finger; Zinc finger at the C-terminus of An1, a ubiquitin-like protein in Xenopus laevis.


Pssm-ID: 197545  Cd Length: 39  Bit Score: 57.40  E-value: 8.00e-12
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 339276075   137 CFMCRKKVGLTGFECR-CGNVYCGVHRYSDVHNCSYNYK 174
Cdd:smart00154   1 CHFCRKKVGLTGFKCRhCGNLFCGEHRLPEDHDCPGDYK 39
zf-A20 pfam01754
A20-like zinc finger; The A20 Zn-finger of bovine/human Rabex5/rabGEF1 is a Ubiquitin Binding ...
 12-35 9.11e-09

A20-like zinc finger; The A20 Zn-finger of bovine/human Rabex5/rabGEF1 is a Ubiquitin Binding Domain. The zinc finger mediates self-association in A20. These fingers also mediate IL-1-induced NF-kappa B activation.


Pssm-ID: 460313  Cd Length: 24  Bit Score: 49.04  E-value: 9.11e-09
                          10        20
                  ....*....|....*....|....
gi 339276075   12 MLCSTGCGFYGNPRTNGMCSVCYK 35
Cdd:pfam01754   1 LLCRNGCGFYGSPATNGLCSKCYK 24
zf-AN1 pfam01428
AN1-like Zinc finger; Zinc finger at the C-terminus of An1, a ubiquitin-like protein in ...
 140-171 1.11e-05

AN1-like Zinc finger; Zinc finger at the C-terminus of An1, a ubiquitin-like protein in Xenopus laevis. The following pattern describes the zinc finger. C-X2-C-X(9-12)-C-X(1-2)-C-X4-C-X2-H-X5-H-X-C Where X can be any amino acid, and numbers in brackets indicate the number of residues.


Pssm-ID: 460208  Cd Length: 37  Bit Score: 40.75  E-value: 1.11e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 339276075  140 CRKKVGLTgFECR-CGNVYCGVHRYSDVHNCSY 171
Cdd:pfam01428   6 CKKKDFLP-FKCRfCGKNFCLKHRLPEDHDCSG 37
ZnF_A20 smart00259
A20-like zinc fingers; A20- (an inhibitor of cell death)-like zinc fingers. The zinc finger ...
 11-35 1.63e-05

A20-like zinc fingers; A20- (an inhibitor of cell death)-like zinc fingers. The zinc finger mediates self-association in A20. These fingers also mediate IL-1-induced NF-kappaB activation.


Pssm-ID: 128555  Cd Length: 26  Bit Score: 40.26  E-value: 1.63e-05
                           10        20
                   ....*....|....*....|....*.
gi 339276075    11 PMLC-STGCGFYGNPRTNGMCSVCYK 35
Cdd:smart00259   1 PIKCrRPGCGFFGNPATEGLCSKCFK 26
 
Name Accession Description Interval E-value
ZnF_AN1 smart00154
AN1-like Zinc finger; Zinc finger at the C-terminus of An1, a ubiquitin-like protein in ...
 137-174 8.00e-12

AN1-like Zinc finger; Zinc finger at the C-terminus of An1, a ubiquitin-like protein in Xenopus laevis.


Pssm-ID: 197545  Cd Length: 39  Bit Score: 57.40  E-value: 8.00e-12
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 339276075   137 CFMCRKKVGLTGFECR-CGNVYCGVHRYSDVHNCSYNYK 174
Cdd:smart00154   1 CHFCRKKVGLTGFKCRhCGNLFCGEHRLPEDHDCPGDYK 39
zf-A20 pfam01754
A20-like zinc finger; The A20 Zn-finger of bovine/human Rabex5/rabGEF1 is a Ubiquitin Binding ...
 12-35 9.11e-09

A20-like zinc finger; The A20 Zn-finger of bovine/human Rabex5/rabGEF1 is a Ubiquitin Binding Domain. The zinc finger mediates self-association in A20. These fingers also mediate IL-1-induced NF-kappa B activation.


Pssm-ID: 460313  Cd Length: 24  Bit Score: 49.04  E-value: 9.11e-09
                          10        20
                  ....*....|....*....|....
gi 339276075   12 MLCSTGCGFYGNPRTNGMCSVCYK 35
Cdd:pfam01754   1 LLCRNGCGFYGSPATNGLCSKCYK 24
zf-AN1 pfam01428
AN1-like Zinc finger; Zinc finger at the C-terminus of An1, a ubiquitin-like protein in ...
 140-171 1.11e-05

AN1-like Zinc finger; Zinc finger at the C-terminus of An1, a ubiquitin-like protein in Xenopus laevis. The following pattern describes the zinc finger. C-X2-C-X(9-12)-C-X(1-2)-C-X4-C-X2-H-X5-H-X-C Where X can be any amino acid, and numbers in brackets indicate the number of residues.


Pssm-ID: 460208  Cd Length: 37  Bit Score: 40.75  E-value: 1.11e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 339276075  140 CRKKVGLTgFECR-CGNVYCGVHRYSDVHNCSY 171
Cdd:pfam01428   6 CKKKDFLP-FKCRfCGKNFCLKHRLPEDHDCSG 37
ZnF_A20 smart00259
A20-like zinc fingers; A20- (an inhibitor of cell death)-like zinc fingers. The zinc finger ...
 11-35 1.63e-05

A20-like zinc fingers; A20- (an inhibitor of cell death)-like zinc fingers. The zinc finger mediates self-association in A20. These fingers also mediate IL-1-induced NF-kappaB activation.


Pssm-ID: 128555  Cd Length: 26  Bit Score: 40.26  E-value: 1.63e-05
                           10        20
                   ....*....|....*....|....*.
gi 339276075    11 PMLC-STGCGFYGNPRTNGMCSVCYK 35
Cdd:smart00259   1 PIKCrRPGCGFFGNPATEGLCSKCFK 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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