NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|334848145|ref|NP_001229348|]
View 

sushi domain-containing protein 6 isoform 1 precursor [Mus musculus]

Protein Classification

CCP domain-containing protein( domain architecture ID 10034019)

complement control protein (CCP) domain-containing proteins are important as cytokine receptors and in neurotransmission, cell adhesion, blood clotting, extracellular matrix formation, hemoglobin metabolism and development, and in the vertebrate complement system

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 63-119 5.55e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.39  E-value: 5.55e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 334848145  63 CPLPPEPENGGYICHprpcKDPLTAGSVIEYLCAEGYMLKGDyKYLTC-KNGEWTPAM 119
Cdd:cd00033    1 CPPPPVPENGTVTGS----KGSYSYGSTVTYSCNEGYTLVGS-STITCtENGGWSPPP 53
 
Name Accession Description Interval E-value
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 63-119 5.55e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.39  E-value: 5.55e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 334848145  63 CPLPPEPENGGYICHprpcKDPLTAGSVIEYLCAEGYMLKGDyKYLTC-KNGEWTPAM 119
Cdd:cd00033    1 CPPPPVPENGTVTGS----KGSYSYGSTVTYSCNEGYTLVGS-STITCtENGGWSPPP 53
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 63-119 2.11e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.91  E-value: 2.11e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 334848145    63 CPLPPEPENGGYICHprpcKDPLTAGSVIEYLCAEGYMLKGDyKYLTC-KNGEWTPAM 119
Cdd:smart00032   1 CPPPPDIENGTVTSS----SGTYSYGDTVTYSCDPGYTLIGS-STITClENGTWSPPP 53
Sushi pfam00084
Sushi repeat (SCR repeat);
63-121 6.70e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.87  E-value: 6.70e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 334848145   63 CPLPPEPENGGYICHprpcKDPLTAGSVIEYLCAEGYMLKGDYKyLTC-KNGEWTPAMEV 121
Cdd:pfam00084   1 CPPPPDIPNGKVSAT----KNEYNYGASVSYECDPGYRLVGSPT-ITCqEDGTWSPPFPE 55
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 63-116 8.61e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 40.41  E-value: 8.61e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 334848145  63 CPLPPEPENG---GYichprpcKDPLTAGSVIEYLCAEGYMLKGDYKYLtCKNGEWT 116
Cdd:PHA02927 148 CQSPPSISNGrhnGY-------EDFYTDGSVVTYSCNSGYSLIGNSGVL-CSGGEWS 196
 
Name Accession Description Interval E-value
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 63-119 5.55e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.39  E-value: 5.55e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 334848145  63 CPLPPEPENGGYICHprpcKDPLTAGSVIEYLCAEGYMLKGDyKYLTC-KNGEWTPAM 119
Cdd:cd00033    1 CPPPPVPENGTVTGS----KGSYSYGSTVTYSCNEGYTLVGS-STITCtENGGWSPPP 53
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 63-119 2.11e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.91  E-value: 2.11e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 334848145    63 CPLPPEPENGGYICHprpcKDPLTAGSVIEYLCAEGYMLKGDyKYLTC-KNGEWTPAM 119
Cdd:smart00032   1 CPPPPDIENGTVTSS----SGTYSYGDTVTYSCDPGYTLIGS-STITClENGTWSPPP 53
Sushi pfam00084
Sushi repeat (SCR repeat);
63-121 6.70e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.87  E-value: 6.70e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 334848145   63 CPLPPEPENGGYICHprpcKDPLTAGSVIEYLCAEGYMLKGDYKyLTC-KNGEWTPAMEV 121
Cdd:pfam00084   1 CPPPPDIPNGKVSAT----KNEYNYGASVSYECDPGYRLVGSPT-ITCqEDGTWSPPFPE 55
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 63-116 8.61e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 40.41  E-value: 8.61e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 334848145  63 CPLPPEPENG---GYichprpcKDPLTAGSVIEYLCAEGYMLKGDYKYLtCKNGEWT 116
Cdd:PHA02927 148 CQSPPSISNGrhnGY-------EDFYTDGSVVTYSCNSGYSLIGNSGVL-CSGGEWS 196
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH