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Conserved domains on  [gi|332801077|ref|NP_001193926|]
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cilia- and flagella-associated protein 299 isoform 1 [Homo sapiens]

Protein Classification

CFAP299 family protein( domain architecture ID 10631528)

CFAP299 family protein is a DUF4464 domain-containing protein; similar to Homo sapiens Cilia- and flagella-associated protein 299 (CFAP299) that may be involved in spermatogenesis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF4464 pfam14713
Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins ...
13-249 8.48e-123

Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins in this family are typically between 224 and 241 amino acids in length. There is a conserved YID sequence motif.


:

Pssm-ID: 464276  Cd Length: 229  Bit Score: 348.39  E-value: 8.48e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332801077   13 IVTQFNAYEDFLDSQITTVDLYYLEDETLARQLVELGYRGTGERVKREDFEARKAAIEIARLAERAQQKTLTSAGKDL-Q 91
Cdd:pfam14713   1 SLLEFNTYEDYLDSFITPEDLRYLENEELARQLVELGYRGTGEVLTREEFEARKKAAEEALLPKGLKPKQLFSAGLDLsK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332801077   92 DNFLTALAMREEDNRSGKLSlnqqetdaahilkkqlaSVIFIRDRNSHGQEISGYIDYAHRLK-------TEDFEVYFTG 164
Cdd:pfam14713  81 DPFLQALAEREEPNRNGKLS-----------------TIIFIRDRNSKGQEISGYIDYAHRLRncrdaskSEDWKAIFEG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332801077  165 KKRLLPRPTDISFYNWDADIAVSNSSPNYQVIADNPEGLLFRYKRDRKILNVDPKAQ-PGDNSTRITILTELYVQAVIFD 243
Cdd:pfam14713 144 KKRLLPRPTDLSYYNWRTGTVTSNDSDNYQVIADNERGLLFKHKGDRKIINVDPGAPnPGDNSTRTMIESPKYGQVVLYD 223

                  ....*.
gi 332801077  244 HISRRK 249
Cdd:pfam14713 224 HVVRRK 229
 
Name Accession Description Interval E-value
DUF4464 pfam14713
Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins ...
13-249 8.48e-123

Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins in this family are typically between 224 and 241 amino acids in length. There is a conserved YID sequence motif.


Pssm-ID: 464276  Cd Length: 229  Bit Score: 348.39  E-value: 8.48e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332801077   13 IVTQFNAYEDFLDSQITTVDLYYLEDETLARQLVELGYRGTGERVKREDFEARKAAIEIARLAERAQQKTLTSAGKDL-Q 91
Cdd:pfam14713   1 SLLEFNTYEDYLDSFITPEDLRYLENEELARQLVELGYRGTGEVLTREEFEARKKAAEEALLPKGLKPKQLFSAGLDLsK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332801077   92 DNFLTALAMREEDNRSGKLSlnqqetdaahilkkqlaSVIFIRDRNSHGQEISGYIDYAHRLK-------TEDFEVYFTG 164
Cdd:pfam14713  81 DPFLQALAEREEPNRNGKLS-----------------TIIFIRDRNSKGQEISGYIDYAHRLRncrdaskSEDWKAIFEG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332801077  165 KKRLLPRPTDISFYNWDADIAVSNSSPNYQVIADNPEGLLFRYKRDRKILNVDPKAQ-PGDNSTRITILTELYVQAVIFD 243
Cdd:pfam14713 144 KKRLLPRPTDLSYYNWRTGTVTSNDSDNYQVIADNERGLLFKHKGDRKIINVDPGAPnPGDNSTRTMIESPKYGQVVLYD 223

                  ....*.
gi 332801077  244 HISRRK 249
Cdd:pfam14713 224 HVVRRK 229
 
Name Accession Description Interval E-value
DUF4464 pfam14713
Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins ...
13-249 8.48e-123

Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins in this family are typically between 224 and 241 amino acids in length. There is a conserved YID sequence motif.


Pssm-ID: 464276  Cd Length: 229  Bit Score: 348.39  E-value: 8.48e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332801077   13 IVTQFNAYEDFLDSQITTVDLYYLEDETLARQLVELGYRGTGERVKREDFEARKAAIEIARLAERAQQKTLTSAGKDL-Q 91
Cdd:pfam14713   1 SLLEFNTYEDYLDSFITPEDLRYLENEELARQLVELGYRGTGEVLTREEFEARKKAAEEALLPKGLKPKQLFSAGLDLsK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332801077   92 DNFLTALAMREEDNRSGKLSlnqqetdaahilkkqlaSVIFIRDRNSHGQEISGYIDYAHRLK-------TEDFEVYFTG 164
Cdd:pfam14713  81 DPFLQALAEREEPNRNGKLS-----------------TIIFIRDRNSKGQEISGYIDYAHRLRncrdaskSEDWKAIFEG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332801077  165 KKRLLPRPTDISFYNWDADIAVSNSSPNYQVIADNPEGLLFRYKRDRKILNVDPKAQ-PGDNSTRITILTELYVQAVIFD 243
Cdd:pfam14713 144 KKRLLPRPTDLSYYNWRTGTVTSNDSDNYQVIADNERGLLFKHKGDRKIINVDPGAPnPGDNSTRTMIESPKYGQVVLYD 223

                  ....*.
gi 332801077  244 HISRRK 249
Cdd:pfam14713 224 HVVRRK 229
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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