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Conserved domains on  [gi|334187330|ref|NP_001190969|]
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shikimate kinase 2 [Arabidopsis thaliana]

Protein Classification

shikimate kinase( domain architecture ID 11476529)

shikimate kinase catalyzes the specific phosphorylation of the 3-hydroxylgroup of shikimic acid using ATP as a cosubstrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02199 PLN02199
shikimate kinase
 1-307 0e+00

shikimate kinase


:

Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 570.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330   1 MEAATVQRFQYSSWNDLRNFEGKP-RGSLRYnTQRIKEDKRFRVVALT--LDKRRDHRLRSV------SDKNSSALLETG 71
Cdd:PLN02199   1 MEAAITQRIQYPSWVDCRKVECKPqRGSLRY-SQQVKVDRRFRGLSLArlQPERRNDQRRAVspavscSDNNSSALLETG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  72 SLLhsPFDEEQqiLKKKAEEVKPYLNGRSMYLLnsflvnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMKGTSVA 151
Cdd:PLN02199  80 SVY--PFDEDI--LKRKAEEVKPYLNGRSMYLV--------GMMGSGKTTVGKLMSKVLGYTFFDCDTLIEQAMNGTSVA 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 152 EIFEHFGESVFREKETEALKKLSLMYhQVVVSTGGGAVIRPINWKYMHKGISIWLDVPLEALAHRIAAVGTGSRPLLHDd 231
Cdd:PLN02199 148 EIFVHHGENFFRGKETDALKKLSSRY-QVVVSTGGGAVIRPINWKYMHKGISIWLDVPLEALAHRIAAVGTDSRPLLHD- 225

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 334187330 232 ESGDTYTAALNRLSTIWDARGEAYTKASARVSLENITLKLGYRSVSDLTPAEIAIEAFEQVQSYLEKEDGMARPDG 307
Cdd:PLN02199 226 ESGDAYSVAFKRLSAIWDERGEAYTNANARVSLENIAAKRGYKNVSDLTPTEIAIEAFEQVLSFLEKEETMEIPDG 301
 
Name Accession Description Interval E-value
PLN02199 PLN02199
shikimate kinase
 1-307 0e+00

shikimate kinase


Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 570.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330   1 MEAATVQRFQYSSWNDLRNFEGKP-RGSLRYnTQRIKEDKRFRVVALT--LDKRRDHRLRSV------SDKNSSALLETG 71
Cdd:PLN02199   1 MEAAITQRIQYPSWVDCRKVECKPqRGSLRY-SQQVKVDRRFRGLSLArlQPERRNDQRRAVspavscSDNNSSALLETG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  72 SLLhsPFDEEQqiLKKKAEEVKPYLNGRSMYLLnsflvnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMKGTSVA 151
Cdd:PLN02199  80 SVY--PFDEDI--LKRKAEEVKPYLNGRSMYLV--------GMMGSGKTTVGKLMSKVLGYTFFDCDTLIEQAMNGTSVA 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 152 EIFEHFGESVFREKETEALKKLSLMYhQVVVSTGGGAVIRPINWKYMHKGISIWLDVPLEALAHRIAAVGTGSRPLLHDd 231
Cdd:PLN02199 148 EIFVHHGENFFRGKETDALKKLSSRY-QVVVSTGGGAVIRPINWKYMHKGISIWLDVPLEALAHRIAAVGTDSRPLLHD- 225

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 334187330 232 ESGDTYTAALNRLSTIWDARGEAYTKASARVSLENITLKLGYRSVSDLTPAEIAIEAFEQVQSYLEKEDGMARPDG 307
Cdd:PLN02199 226 ESGDAYSVAFKRLSAIWDERGEAYTNANARVSLENIAAKRGYKNVSDLTPTEIAIEAFEQVLSFLEKEETMEIPDG 301
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 107-271 1.09e-51

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 167.35  E-value: 1.09e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 107 FLVnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMkGTSVAEIFEHFGESVFREKETEALKKLSLMyHQVVVSTGG 186
Cdd:cd00464    3 VLI---GMMGAGKTTVGRLLAKALGLPFVDLDELIEQRA-GMSIPEIFAEEGEEGFRELEREVLLLLLTK-ENAVIATGG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 187 GAVIRPINWKYM-HKGISIWLDVPLEALAHRIAAvgTGSRPLLHDDESGdtytaalnRLSTIWDARGEAYTK-ASARVSL 264
Cdd:cd00464   78 GAVLREENRRLLlENGIVVWLDASPEELLERLAR--DKTRPLLQDEDPE--------RLRELLEEREPLYREvADLTIDT 147


                 ....*..
gi 334187330 265 ENITLKL 271
Cdd:cd00464  148 DELSPEE 154
SKI pfam01202
Shikimate kinase;
115-293 1.10e-49

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 162.37  E-value: 1.10e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  115 MGSGKTTVGKIMARSLGYTFFDCDTLIEQAMkGTSVAEIFEHFGESVFREKETEALKKLsLMYHQVVVSTGGGAVIRPIN 194
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRT-GMSIAEIFEEEGEEGFRRLESEVLKEL-LAEHGLVIATGGGAVLSEEN 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  195 WKYMHK-GISIWLDVPLEALAHRIAAvgTGSRPLLHDDESgdtytaALNRLSTIWDARGEAYTKASARVSLENitlklgy 273
Cdd:pfam01202  79 RDLLKErGIVIYLDAPLEVLLERLKR--DKTRPLLQNKDP------EEELLELLFEERDPLYEEAADIVIDTD------- 143

                         170       180
                  ....*....|....*....|
gi 334187330  274 rsvsDLTPAEIAIEAFEQVQ 293
Cdd:pfam01202 144 ----ESSPEEVATEILEALE 159
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 107-294 3.75e-49

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 161.06  E-value: 3.75e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 107 FLVnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMkGTSVAEIFEHFGESVFREKETEALKKLsLMYHQVVVSTGG 186
Cdd:COG0703    2 VLI---GMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERA-GMSIPEIFAEEGEAGFRELEREVLAEL-LEEENAVIATGG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 187 GAVIRPINWKYMHK-GISIWLDVPLEALAHRIAAvgTGSRPLLHDDESGDtytaalnRLSTIWDARGEAYTKASarvsle 265
Cdd:COG0703   77 GAVLSPENRELLKEhGTVVYLDASPETLLERLRR--DDNRPLLQGEDPRE-------RLEELLAEREPLYREVA------ 141

                        170       180
                 ....*....|....*....|....*....
gi 334187330 266 NITLklgyrSVSDLTPAEIAIEAFEQVQS 294
Cdd:COG0703  142 DITV-----DTDGRSPEEVVDEILEALEE 165
TIGR00152 TIGR00152
dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, ...
 108-210 9.56e-05

dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, guanylate, uridine, and thymidylate kinases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A]


Pssm-ID: 272931  Cd Length: 190  Bit Score: 42.38  E-value: 9.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  108 LVNALGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAM--KGTSVAEIFEHFGESVFREKET--------------EALK 171
Cdd:TIGR00152   1 LIALTGGIGSGKSTVLQYLADKYHFPVIDADKIAHQVVepGQPAYHAIADHFGANILNQDGEldrkalgnyvfndpEELK 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 334187330  172 KLSLMYHQVVvstggGAVIRPINWKYMHKGISIWLDVPL 210
Cdd:TIGR00152  81 WLNALTHPLI-----RQWMKKLIAQFQSKYALVLLDVPL 114
 
Name Accession Description Interval E-value
PLN02199 PLN02199
shikimate kinase
 1-307 0e+00

shikimate kinase


Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 570.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330   1 MEAATVQRFQYSSWNDLRNFEGKP-RGSLRYnTQRIKEDKRFRVVALT--LDKRRDHRLRSV------SDKNSSALLETG 71
Cdd:PLN02199   1 MEAAITQRIQYPSWVDCRKVECKPqRGSLRY-SQQVKVDRRFRGLSLArlQPERRNDQRRAVspavscSDNNSSALLETG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  72 SLLhsPFDEEQqiLKKKAEEVKPYLNGRSMYLLnsflvnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMKGTSVA 151
Cdd:PLN02199  80 SVY--PFDEDI--LKRKAEEVKPYLNGRSMYLV--------GMMGSGKTTVGKLMSKVLGYTFFDCDTLIEQAMNGTSVA 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 152 EIFEHFGESVFREKETEALKKLSLMYhQVVVSTGGGAVIRPINWKYMHKGISIWLDVPLEALAHRIAAVGTGSRPLLHDd 231
Cdd:PLN02199 148 EIFVHHGENFFRGKETDALKKLSSRY-QVVVSTGGGAVIRPINWKYMHKGISIWLDVPLEALAHRIAAVGTDSRPLLHD- 225

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 334187330 232 ESGDTYTAALNRLSTIWDARGEAYTKASARVSLENITLKLGYRSVSDLTPAEIAIEAFEQVQSYLEKEDGMARPDG 307
Cdd:PLN02199 226 ESGDAYSVAFKRLSAIWDERGEAYTNANARVSLENIAAKRGYKNVSDLTPTEIAIEAFEQVLSFLEKEETMEIPDG 301
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 107-271 1.09e-51

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 167.35  E-value: 1.09e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 107 FLVnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMkGTSVAEIFEHFGESVFREKETEALKKLSLMyHQVVVSTGG 186
Cdd:cd00464    3 VLI---GMMGAGKTTVGRLLAKALGLPFVDLDELIEQRA-GMSIPEIFAEEGEEGFRELEREVLLLLLTK-ENAVIATGG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 187 GAVIRPINWKYM-HKGISIWLDVPLEALAHRIAAvgTGSRPLLHDDESGdtytaalnRLSTIWDARGEAYTK-ASARVSL 264
Cdd:cd00464   78 GAVLREENRRLLlENGIVVWLDASPEELLERLAR--DKTRPLLQDEDPE--------RLRELLEEREPLYREvADLTIDT 147


                 ....*..
gi 334187330 265 ENITLKL 271
Cdd:cd00464  148 DELSPEE 154
SKI pfam01202
Shikimate kinase;
115-293 1.10e-49

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 162.37  E-value: 1.10e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  115 MGSGKTTVGKIMARSLGYTFFDCDTLIEQAMkGTSVAEIFEHFGESVFREKETEALKKLsLMYHQVVVSTGGGAVIRPIN 194
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRT-GMSIAEIFEEEGEEGFRRLESEVLKEL-LAEHGLVIATGGGAVLSEEN 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  195 WKYMHK-GISIWLDVPLEALAHRIAAvgTGSRPLLHDDESgdtytaALNRLSTIWDARGEAYTKASARVSLENitlklgy 273
Cdd:pfam01202  79 RDLLKErGIVIYLDAPLEVLLERLKR--DKTRPLLQNKDP------EEELLELLFEERDPLYEEAADIVIDTD------- 143

                         170       180
                  ....*....|....*....|
gi 334187330  274 rsvsDLTPAEIAIEAFEQVQ 293
Cdd:pfam01202 144 ----ESSPEEVATEILEALE 159
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 107-294 3.75e-49

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 161.06  E-value: 3.75e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 107 FLVnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMkGTSVAEIFEHFGESVFREKETEALKKLsLMYHQVVVSTGG 186
Cdd:COG0703    2 VLI---GMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERA-GMSIPEIFAEEGEAGFRELEREVLAEL-LEEENAVIATGG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 187 GAVIRPINWKYMHK-GISIWLDVPLEALAHRIAAvgTGSRPLLHDDESGDtytaalnRLSTIWDARGEAYTKASarvsle 265
Cdd:COG0703   77 GAVLSPENRELLKEhGTVVYLDASPETLLERLRR--DDNRPLLQGEDPRE-------RLEELLAEREPLYREVA------ 141

                        170       180
                 ....*....|....*....|....*....
gi 334187330 266 NITLklgyrSVSDLTPAEIAIEAFEQVQS 294
Cdd:COG0703  142 DITV-----DTDGRSPEEVVDEILEALEE 165
aroK PRK00131
shikimate kinase; Reviewed
 105-298 3.14e-45

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 151.50  E-value: 3.14e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 105 NSFLVnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMkGTSVAEIFEHFGESVFREKETEALKKLsLMYHQVVVST 184
Cdd:PRK00131   6 NIVLI---GFMGAGKSTIGRLLAKRLGYDFIDTDHLIEARA-GKSIPEIFEEEGEAAFRELEEEVLAEL-LARHNLVIST 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 185 GGGAVIRPINWKYM-HKGISIWLDVPLEALAHRIAavGTGSRPLLHDDESGDtytaalnRLSTIWDARGEAYTKASarvs 263
Cdd:PRK00131  81 GGGAVLREENRALLrERGTVVYLDASFEELLRRLR--RDRNRPLLQTNDPKE-------KLRDLYEERDPLYEEVA---- 147

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 334187330 264 leNITLKlgyrsVSDLTPAEIAIEAFEQVQSYLEK 298
Cdd:PRK00131 148 --DITVE-----TDGRSPEEVVNEILEKLEAAWRR 175
PRK13946 PRK13946
shikimate kinase; Provisional
 113-299 2.31e-29

shikimate kinase; Provisional


Pssm-ID: 184411 [Multi-domain]  Cd Length: 184  Bit Score: 110.40  E-value: 2.31e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 113 GMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAmKGTSVAEIFEHFGESVFREKETEALKKLsLMYHQVVVSTGGGAVIRP 192
Cdd:PRK13946  17 GLMGAGKSTVGRRLATMLGLPFLDADTEIERA-ARMTIAEIFAAYGEPEFRDLERRVIARL-LKGGPLVLATGGGAFMNE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 193 INWKYMH-KGISIWLDVPLEALAHRIAAVGTgsRPLLHDDESGDTytaalnrLSTIWDARGEAYTKAsarvsleNITLKL 271
Cdd:PRK13946  95 ETRAAIAeKGISVWLKADLDVLWERVSRRDT--RPLLRTADPKET-------LARLMEERYPVYAEA-------DLTVAS 158

                        170       180
                 ....*....|....*....|....*...
gi 334187330 272 GyrsvsDLTPAEIAIEAFEQVQSYLEKE 299
Cdd:PRK13946 159 R-----DVPKEVMADEVIEALAAYLEKE 181
PRK13947 PRK13947
shikimate kinase; Provisional
 113-295 2.83e-28

shikimate kinase; Provisional


Pssm-ID: 184412 [Multi-domain]  Cd Length: 171  Bit Score: 107.10  E-value: 2.83e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 113 GMMGSGKTTVGKIMARSLGYTFFDCDTLIEQaMKGTSVAEIFEHFGESVFREKETEALKKLSLMYHQvVVSTGGGAVIRP 192
Cdd:PRK13947   8 GFMGTGKTTVGKRVATTLSFGFIDTDKEIEK-MTGMTVAEIFEKDGEVRFRSEEKLLVKKLARLKNL-VIATGGGVVLNP 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 193 INWKYMHK-GISIWLDVPLEALAHRIAAvgTGSRPLLHDDEsgdtytaALNRLSTIWDARGEAYTKASARVslenitlkl 271
Cdd:PRK13947  86 ENVVQLRKnGVVICLKARPEVILRRVGK--KKSRPLLMVGD-------PEERIKELLKEREPFYDFADYTI--------- 147

                        170       180
                 ....*....|....*....|....*..
gi 334187330 272 gyrSVSDLTPAEIA---IEAFEQVQSY 295
Cdd:PRK13947 148 ---DTGDMTIDEVAeeiIKAYLKLKNG 171
aroL PRK03731
shikimate kinase AroL;
107-219 2.81e-26

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 101.94  E-value: 2.81e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 107 FLVnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIeQAMKGTSVAEIFEHFGESVFREKETEALKKLSLmyHQVVVSTGG 186
Cdd:PRK03731   6 FLV---GARGCGKTTVGMALAQALGYRFVDTDQWL-QSTSNMTVAEIVEREGWAGFRARESAALEAVTA--PSTVIATGG 79

                         90       100       110
                 ....*....|....*....|....*....|....
gi 334187330 187 GAVIRPINWKYMH-KGISIWLDVPLEALAHRIAA 219
Cdd:PRK03731  80 GIILTEENRHFMRnNGIVIYLCAPVSVLANRLEA 113
PRK13948 PRK13948
shikimate kinase; Provisional
 113-266 2.52e-23

shikimate kinase; Provisional


Pssm-ID: 184413 [Multi-domain]  Cd Length: 182  Bit Score: 94.47  E-value: 2.52e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 113 GMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMkGTSVAEIFEHFGESVFREKETEALKKLSLMYHqVVVSTGGGAVIRP 192
Cdd:PRK13948  17 GFMGTGKSRIGWELSRALMLHFIDTDRYIERVT-GKSIPEIFRHLGEAYFRRCEAEVVRRLTRLDY-AVISLGGGTFMHE 94

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 334187330 193 IN-WKYMHKGISIWLDVPLEALAHRIAAvgtGSRPLLhddESGDtytaALNRLSTIWDARGEAYTKASARVSLEN 266
Cdd:PRK13948  95 ENrRKLLSRGPVVVLWASPETIYERTRP---GDRPLL---QVED----PLGRIRTLLNEREPVYRQATIHVSTDG 159
PRK13949 PRK13949
shikimate kinase; Provisional
 107-259 5.55e-23

shikimate kinase; Provisional


Pssm-ID: 140006 [Multi-domain]  Cd Length: 169  Bit Score: 93.26  E-value: 5.55e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 107 FLVnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMKGTsVAEIFEHFGESVFREKETEALKKLSLMyHQVVVSTGG 186
Cdd:PRK13949   5 FLV---GYMGAGKTTLGKALARELGLSFIDLDFFIENRFHKT-VGDIFAERGEAVFRELERNMLHEVAEF-EDVVISTGG 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 334187330 187 GAVIRPINWKYMHK-GISIWLDVPLEALAHRIaAVGTGSRPLLHD---DESGDTYTAALNRlstiwdaRGEAYTKAS 259
Cdd:PRK13949  80 GAPCFFDNMELMNAsGTTVYLKVSPEVLFVRL-RLAKQQRPLLKGksdEELLDFIIEALEK-------RAPFYRQAK 148
PRK13951 PRK13951
bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;
107-257 3.17e-22

bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;


Pssm-ID: 172457 [Multi-domain]  Cd Length: 488  Bit Score: 96.51  E-value: 3.17e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 107 FLVnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAmKGTSVAEIFEHFGESVFREKETEALKKLsLMYHQVVVSTGG 186
Cdd:PRK13951   4 FLV---GMMGSGKSTIGKRVSEVLDLQFIDMDEEIERR-EGRSVRRIFEEDGEEYFRLKEKELLREL-VERDNVVVATGG 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334187330 187 GAVIRPINWKYMHKGISIWLDVPLEALAHRiaaVGTGSRPLLHDDESgdtytaalnRLSTIWDARGEAYTK 257
Cdd:PRK13951  79 GVVIDPENRELLKKEKTLFLYAPPEVLMER---VTTENRPLLREGKE---------RIREIWERRKQFYTE 137
aroK PRK05057
shikimate kinase AroK;
105-233 1.18e-14

shikimate kinase AroK;


Pssm-ID: 235335 [Multi-domain]  Cd Length: 172  Bit Score: 70.51  E-value: 1.18e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 105 NSFLVnalGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQaMKGTSVAEIFEHFGESVFREKETEALKKLSlMYHQVVVST 184
Cdd:PRK05057   6 NIFLV---GPMGAGKSTIGRQLAQQLNMEFYDSDQEIEK-RTGADIGWVFDVEGEEGFRDREEKVINELT-EKQGIVLAT 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 334187330 185 GGGAVIRPINWKYMH-KGISIWLDVPLEALAHRIAAvgTGSRPLLHDDES 233
Cdd:PRK05057  81 GGGSVKSRETRNRLSaRGVVVYLETTIEKQLARTQR--DKKRPLLQVDDP 128
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 112-288 6.15e-14

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 70.75  E-value: 6.15e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 112 LGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQaMKGTSVAEIFEHFGESVFREKETEALKKLSLMYHQVVVSTGGGAVIR 191
Cdd:PRK08154 139 IGLRGAGKSTLGRMLAARLGVPFVELNREIER-EAGLSVSEIFALYGQEGYRRLERRALERLIAEHEEMVLATGGGIVSE 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 192 PINWKYM-HKGISIWLDV-PLEALAhRIAAVGTgSRPLLHDDEsgdtytaALNRLSTIWDARGEAYTKASARVSLENITL 269
Cdd:PRK08154 218 PATFDLLlSHCYTVWLKAsPEEHMA-RVRAQGD-LRPMADNRE-------AMEDLRRILASREPLYARADAVVDTSGLTV 288

                        170
                 ....*....|....*....
gi 334187330 270 KLGYRSVSDLTPAEIAIEA 288
Cdd:PRK08154 289 AQSLARLRELVRPALGLPA 307
PRK14021 PRK14021
bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional
 112-231 2.25e-12

bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional


Pssm-ID: 184458 [Multi-domain]  Cd Length: 542  Bit Score: 67.19  E-value: 2.25e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 112 LGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMkGTSVAEIFEHFGESVFREKETEALKKLsLMYHQVVVSTGGGAVIR 191
Cdd:PRK14021  12 IGMMGAGKTRVGKEVAQMMRLPFADADVEIEREI-GMSIPSYFEEYGEPAFREVEADVVADM-LEDFDGIFSLGGGAPMT 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 334187330 192 PINWK----YM-HKGISIWLDV-PLEALAHriaAVGTGSRPLLHDD 231
Cdd:PRK14021  90 PSTQHalasYIaHGGRVVYLDAdPKEAMER---ANRGGGRPMLNGD 132
PRK00625 PRK00625
shikimate kinase; Provisional
 113-249 9.04e-11

shikimate kinase; Provisional


Pssm-ID: 134335 [Multi-domain]  Cd Length: 173  Bit Score: 59.77  E-value: 9.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 113 GMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMKG---TSVAEIFEHFGESVFREKETEALKKLSLMyHQVVVSTGGGAV 189
Cdd:PRK00625   7 GLPTVGKTSFGKALAKFLSLPFFDTDDLIVSNYHGalySSPKEIYQAYGEEGFCREEFLALTSLPVI-PSIVALGGGTLM 85

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 190 IRPINWKYMHKGISIWLDVPLEALAHRIAAVGTGSRpLLHDDESGDTYTAALNRLSTIWD 249
Cdd:PRK00625  86 IEPSYAHIRNRGLLVLLSLPIATIYQRLQKRGLPER-LKHAPSLEEILSQRIDRMRSIAD 144
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
113-218 6.25e-08

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 51.75  E-value: 6.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 113 GMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMK-GTSVAEiFEHFGESVFREKETEALKKLSLMYHQ------------ 179
Cdd:COG1102    7 REPGSGGTTIAKRLAEKLGLPLYDGEILREAAKErGLSEEE-FEKLDEKAPSLLYRDTAEEDEIDRALdkvirelarkgn 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 334187330 180 -VVVSTGGGAVIRPinwkyMHKGISIWLDVPLEALAHRIA 218
Cdd:COG1102   86 cVIVGRLADWILRD-----RPNVLKVFLTAPLEVRVKRIA 120
DPCK cd02022
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of ...
 113-181 5.18e-07

Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.


Pssm-ID: 238980  Cd Length: 179  Bit Score: 49.05  E-value: 5.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 113 GMMGSGKTTVGKIMaRSLGYTFFDCDTLIEQAM-KGTSV-AEIFEHFGESVFREKET--------------EALKKLSLM 176
Cdd:cd02022    6 GGIGSGKSTVAKLL-KELGIPVIDADKIAHEVYePGGPAlQAIVEAFGPDILLEDGEldrkklgeivfadpEKRKKLEAI 84


                 ....*
gi 334187330 177 YHQVV 181
Cdd:cd02022   85 THPLI 89
CoaE COG0237
Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the ...
 113-164 6.85e-06

Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 440007  Cd Length: 193  Bit Score: 45.83  E-value: 6.85e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 334187330 113 GMMGSGKTTVGKIMARsLGYTFFDCDTLIEQAM-KGTSV-AEIFEHFGESVFRE 164
Cdd:COG0237    8 GGIGSGKSTVARMFAE-LGAPVIDADAIARELVePGGPAlAAIVEAFGEEILDA 60
AAA_18 pfam13238
AAA domain;
113-225 1.42e-05

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 43.96  E-value: 1.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  113 GMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAMKGTSVAEIFEHFGesVFREKETEALKKL----SLMYHQVVVSTGGGA 188
Cdd:pfam13238   5 GTPGVGKTTLAKELSKRLGFGDNVRDLALENGLVLGDDPETRESKR--LDEDKLDRLLDLLeenaALEEGGNLIIDGHLA 82

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 334187330  189 VIRPINWKYMHkgiSIWLDVPLEALAHRIAAVGTGSR 225
Cdd:pfam13238  83 ELEPERAKDLV---GIVLRASPEELLERLEKRGYEEA 116
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 116-146 6.23e-05

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 42.42  E-value: 6.23e-05
                         10        20        30
                 ....*....|....*....|....*....|.
gi 334187330 116 GSGKTTVGKIMARSLGYTFFDCDTLIEQAMK 146
Cdd:COG3265   11 GSGKSTVGQALAERLGWPFIDGDDFHPPANI 41
TIGR00152 TIGR00152
dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, ...
 108-210 9.56e-05

dephospho-CoA kinase; This model produces scores in the range of 0-25 bits against adenylate, guanylate, uridine, and thymidylate kinases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A]


Pssm-ID: 272931  Cd Length: 190  Bit Score: 42.38  E-value: 9.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  108 LVNALGMMGSGKTTVGKIMARSLGYTFFDCDTLIEQAM--KGTSVAEIFEHFGESVFREKET--------------EALK 171
Cdd:TIGR00152   1 LIALTGGIGSGKSTVLQYLADKYHFPVIDADKIAHQVVepGQPAYHAIADHFGANILNQDGEldrkalgnyvfndpEELK 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 334187330  172 KLSLMYHQVVvstggGAVIRPINWKYMHKGISIWLDVPL 210
Cdd:TIGR00152  81 WLNALTHPLI-----RQWMKKLIAQFQSKYALVLLDVPL 114
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 113-218 1.39e-04

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 41.64  E-value: 1.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330  113 GMMGSGKTTVGKIMARSLGYTFFDCDTLIEQ--AMKGTSVAEIFEHFGES------VFREKETEALKKLSLmyhqVVVST 184
Cdd:TIGR02173   7 GPPGSGKTTVAKILAEKLSLKLISAGDIFRElaAKMGLDLIEFLNYAEENpeidkkIDRRIHEIALKEKNV----VLESR 82

                          90       100       110
                  ....*....|....*....|....*....|....
gi 334187330  185 GGGAVIRPInwkymhKGISIWLDVPLEALAHRIA 218
Cdd:TIGR02173  83 LAGWIVREY------ADVKIWLKAPLEVRARRIA 110
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 116-219 1.19e-03

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 38.62  E-value: 1.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 116 GSGKTTVGKIMARSLGYTFFdcDT----LIEQAMKGTSVAEIFEhfgesvFREKETEALKKLSlMYHQVVV-STGGGAVI 190
Cdd:cd02020    9 GSGKSTVAKLLAKKLGLPYL--DTggirTEEVGKLASEVAAIPE------VRKALDERQRELA-KKPGIVLeGRDIGTVV 79

                         90       100
                 ....*....|....*....|....*....
gi 334187330 191 RPINwkymhkGISIWLDVPLEALAHRIAA 219
Cdd:cd02020   80 FPDA------DLKIFLTASPEVRAKRRAK 102
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 116-140 1.88e-03

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 38.00  E-value: 1.88e-03
                         10        20
                 ....*....|....*....|....*
gi 334187330 116 GSGKTTVGKIMARSLGYTFFDCDTL 140
Cdd:cd02021    9 GSGKSTVGKALAERLGAPFIDGDDL 33
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
113-219 6.59e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 36.81  E-value: 6.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187330 113 GMMGSGKTTVGKIMARSLGYTFFDCDTlIEQAMKGTSVAEiFEHFGEsvFREKETEALKKLSLMY----HQVVV-STGGG 187
Cdd:COG0645    6 GLPGSGKSTLARALAERLGAVRLRSDV-VRKRLFGAGLAP-LERSPE--ATARTYARLLALARELlaagRSVILdATFLR 81

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 334187330 188 AVIRPinwKYMH----KGIS---IWLDVPLEALAHRIAA 219
Cdd:COG0645   82 RAQRE---AFRAlaeeAGAPfvlIWLDAPEEVLRERLEA 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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