SIN3-like 1 [Arabidopsis thaliana]
Sin3 family protein( domain architecture ID 13432989)
Sin3 family protein similar to Homo sapiens paired amphipathic helix proteins Sin3a and Sin3b, which act as transcriptional repressors
List of domain hits
Name | Accession | Description | Interval | E-value | ||||||||||
Sin3 super family | cl35027 | Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]; |
13-660 | 4.82e-89 | ||||||||||
Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]; The actual alignment was detected with superfamily member COG5602: Pssm-ID: 227889 [Multi-domain] Cd Length: 1163 Bit Score: 314.93 E-value: 4.82e-89
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Sin3a_C | pfam16879 | C-terminal domain of Sin3a protein; Sin3a_C is a family of eukaryotic species. It is found at ... |
1088-1331 | 4.85e-52 | ||||||||||
C-terminal domain of Sin3a protein; Sin3a_C is a family of eukaryotic species. It is found at the C-terminus of the co-repressor Sin3a, and downstream of family Sin3_corepress, pfam08295. : Pssm-ID: 465294 Cd Length: 281 Bit Score: 184.73 E-value: 4.85e-52
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2A1904 super family | cl36772 | K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
919-1060 | 2.16e-03 | ||||||||||
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds] The actual alignment was detected with superfamily member TIGR00927: Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 42.68 E-value: 2.16e-03
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Name | Accession | Description | Interval | E-value | ||||||||||
Sin3 | COG5602 | Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]; |
13-660 | 4.82e-89 | ||||||||||
Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]; Pssm-ID: 227889 [Multi-domain] Cd Length: 1163 Bit Score: 314.93 E-value: 4.82e-89
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Sin3a_C | pfam16879 | C-terminal domain of Sin3a protein; Sin3a_C is a family of eukaryotic species. It is found at ... |
1088-1331 | 4.85e-52 | ||||||||||
C-terminal domain of Sin3a protein; Sin3a_C is a family of eukaryotic species. It is found at the C-terminus of the co-repressor Sin3a, and downstream of family Sin3_corepress, pfam08295. Pssm-ID: 465294 Cd Length: 281 Bit Score: 184.73 E-value: 4.85e-52
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HDAC_interact | smart00761 | Histone deacetylase (HDAC) interacting; This domain is found on transcriptional regulators. It ... |
455-551 | 5.38e-45 | ||||||||||
Histone deacetylase (HDAC) interacting; This domain is found on transcriptional regulators. It forms interactions with histone deacetylases. Pssm-ID: 214808 [Multi-domain] Cd Length: 102 Bit Score: 157.47 E-value: 5.38e-45
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Sin3_corepress | pfam08295 | Sin3 family co-repressor; This domain is found on transcriptional regulators. It forms ... |
457-550 | 1.61e-39 | ||||||||||
Sin3 family co-repressor; This domain is found on transcriptional regulators. It forms interactions with histone deacetylases. Pssm-ID: 462418 Cd Length: 97 Bit Score: 141.60 E-value: 1.61e-39
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Sin3 | COG5602 | Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]; |
1080-1329 | 5.09e-13 | ||||||||||
Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]; Pssm-ID: 227889 [Multi-domain] Cd Length: 1163 Bit Score: 74.18 E-value: 5.09e-13
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HN_RTEL1 | cd13932 | harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL); ... |
46-144 | 4.54e-04 | ||||||||||
harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL); Mouse Rtel is an essential protein required for the maintenance of both telomeric and genomic stability. RTEL1 appears to maintain genome stability by suppressing homologous recombination (HR). In vitro, purified human and insect RTEL1 have been shown to promote the disassembly of D loop recombination intermediates, in a reaction dependent upon ATP hydrolysis. Human RTEL1 is implicated in the etiology of Dyskeratosis congenital (DC, is an inherited bone marrow failure and cancer predisposition syndrome). Point mutations in its helicase domains, and truncations which result in loss of its C-terminus have been discovered in DC families. RTEL1 is also a candidate gene influencing glioma susceptibility. The C-terminal domain of RTEL1, represented here, appears similar to the N-terminal domain of the scaffolding protein harmonin. Pssm-ID: 259826 [Multi-domain] Cd Length: 99 Bit Score: 40.72 E-value: 4.54e-04
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2A1904 | TIGR00927 | K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
919-1060 | 2.16e-03 | ||||||||||
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds] Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 42.68 E-value: 2.16e-03
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PHA03169 | PHA03169 | hypothetical protein; Provisional |
874-1060 | 4.78e-03 | ||||||||||
hypothetical protein; Provisional Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 41.11 E-value: 4.78e-03
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Name | Accession | Description | Interval | E-value | ||||||||||
Sin3 | COG5602 | Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]; |
13-660 | 4.82e-89 | ||||||||||
Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]; Pssm-ID: 227889 [Multi-domain] Cd Length: 1163 Bit Score: 314.93 E-value: 4.82e-89
|
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Sin3a_C | pfam16879 | C-terminal domain of Sin3a protein; Sin3a_C is a family of eukaryotic species. It is found at ... |
1088-1331 | 4.85e-52 | ||||||||||
C-terminal domain of Sin3a protein; Sin3a_C is a family of eukaryotic species. It is found at the C-terminus of the co-repressor Sin3a, and downstream of family Sin3_corepress, pfam08295. Pssm-ID: 465294 Cd Length: 281 Bit Score: 184.73 E-value: 4.85e-52
|
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HDAC_interact | smart00761 | Histone deacetylase (HDAC) interacting; This domain is found on transcriptional regulators. It ... |
455-551 | 5.38e-45 | ||||||||||
Histone deacetylase (HDAC) interacting; This domain is found on transcriptional regulators. It forms interactions with histone deacetylases. Pssm-ID: 214808 [Multi-domain] Cd Length: 102 Bit Score: 157.47 E-value: 5.38e-45
|
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Sin3_corepress | pfam08295 | Sin3 family co-repressor; This domain is found on transcriptional regulators. It forms ... |
457-550 | 1.61e-39 | ||||||||||
Sin3 family co-repressor; This domain is found on transcriptional regulators. It forms interactions with histone deacetylases. Pssm-ID: 462418 Cd Length: 97 Bit Score: 141.60 E-value: 1.61e-39
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PAH | pfam02671 | Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The ... |
159-203 | 1.86e-15 | ||||||||||
Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions. Pssm-ID: 460645 [Multi-domain] Cd Length: 45 Bit Score: 71.30 E-value: 1.86e-15
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PAH | pfam02671 | Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The ... |
74-118 | 3.21e-15 | ||||||||||
Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions. Pssm-ID: 460645 [Multi-domain] Cd Length: 45 Bit Score: 70.53 E-value: 3.21e-15
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PAH | pfam02671 | Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The ... |
341-385 | 2.26e-13 | ||||||||||
Paired amphipathic helix repeat; This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions. Pssm-ID: 460645 [Multi-domain] Cd Length: 45 Bit Score: 65.52 E-value: 2.26e-13
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Sin3 | COG5602 | Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]; |
1080-1329 | 5.09e-13 | ||||||||||
Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]; Pssm-ID: 227889 [Multi-domain] Cd Length: 1163 Bit Score: 74.18 E-value: 5.09e-13
|
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HN_RTEL1 | cd13932 | harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL); ... |
46-144 | 4.54e-04 | ||||||||||
harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL); Mouse Rtel is an essential protein required for the maintenance of both telomeric and genomic stability. RTEL1 appears to maintain genome stability by suppressing homologous recombination (HR). In vitro, purified human and insect RTEL1 have been shown to promote the disassembly of D loop recombination intermediates, in a reaction dependent upon ATP hydrolysis. Human RTEL1 is implicated in the etiology of Dyskeratosis congenital (DC, is an inherited bone marrow failure and cancer predisposition syndrome). Point mutations in its helicase domains, and truncations which result in loss of its C-terminus have been discovered in DC families. RTEL1 is also a candidate gene influencing glioma susceptibility. The C-terminal domain of RTEL1, represented here, appears similar to the N-terminal domain of the scaffolding protein harmonin. Pssm-ID: 259826 [Multi-domain] Cd Length: 99 Bit Score: 40.72 E-value: 4.54e-04
|
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2A1904 | TIGR00927 | K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
919-1060 | 2.16e-03 | ||||||||||
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds] Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 42.68 E-value: 2.16e-03
|
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PHA03169 | PHA03169 | hypothetical protein; Provisional |
874-1060 | 4.78e-03 | ||||||||||
hypothetical protein; Provisional Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 41.11 E-value: 4.78e-03
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PHA03169 | PHA03169 | hypothetical protein; Provisional |
903-1043 | 5.31e-03 | ||||||||||
hypothetical protein; Provisional Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 40.72 E-value: 5.31e-03
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Blast search parameters | ||||
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