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Conserved domains on  [gi|334184821|ref|NP_001189711|]
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CAP-gly domain linker [Arabidopsis thaliana]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1005088)

coiled-coil domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CCDC158 super family cl37899
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 203-801 2.27e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


The actual alignment was detected with superfamily member pfam15921:

Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 2.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   203 LDSNSDVLAnvvVPLTEEYEPVNEYYPDDQTELQY-----------QQFFLHG---------KDMCKEDDVSSELEKRYK 262
Cdd:pfam15921   61 LDSPRKIIA---YPGKEHIERVLEEYSHQVKDLQRrlnesnelhekQKFYLRQsvidlqtklQEMQMERDAMADIRRRES 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   263 EAEK----RVKLLSEEMEEKKFL-SDCDFDISSLVGDIRQMEEERVGLAFEVLSLLrsqMDERASTREDIRRVKNDWDLL 337
Cdd:pfam15921  138 QSQEdlrnQLQNTVHELEAAKCLkEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL---VDFEEASGKKIYEHDSMSTMH 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   338 LKRLEKEKTELQVQLETE---LDRRSSEWTSKVESFKVEEKRLRERVreLAEHNVSLQREISTfHEKE----TERIDMIR 410
Cdd:pfam15921  215 FRSLGSAISKILRELDTEisyLKGRIFPVEDQLEALKSESQNKIELL--LQQHQDRIEQLISE-HEVEitglTEKASSAR 291

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   411 HLDETV-TELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNFEEKdmeCKELHKSVtrLLRTCKEQEKTIQgl 489
Cdd:pfam15921  292 SQANSIqSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDK---IEELEKQL--VLANSELTEARTE-- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   490 RDGFSEE--------------IKKQPSEHVDKKLQMEQL--RLVGVELS---LRKEVESMKLEAESLRRENNCLLNRVKG 550
Cdd:pfam15921  365 RDQFSQEsgnlddqlqklladLHKREKELSLEKEQNKRLwdRDTGNSITidhLRRELDDRNMEVQRLEALLKAMKSECQG 444

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   551 NGEEAdiMTTFKLDNEMKMRVCHLQDQgismLNESTQLCYKFLKIIKEKSVNSGWSEQFLIESEMRVHGIRRGTESLKRS 630
Cdd:pfam15921  445 QMERQ--MAAIQGKNESLEKVSSLTAQ----LESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAE 518

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   631 LQTVTSLLLEKSNEMASNSESSCSSAARPSSRsveKSLRAELRAETLVTSLLReklyskeQEIEQLHAEVAAGVRGNEVL 710
Cdd:pfam15921  519 ITKLRSRVDLKLQELQHLKNEGDHLRNVQTEC---EALKLQMAEKDKVIEILR-------QQIENMTQLVGQHGRTAGAM 588

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   711 QCEIQNVLDNLSLNNHQLKDLKLQMVKKDENINRME----------INLQEAAKELLTLPK-VLEEREEMWKEVKECRKR 779
Cdd:pfam15921  589 QVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEarvsdlelekVKLVNAGSERLRAVKdIKQERDQLLNEVKTSRNE 668

                          650       660
                   ....*....|....*....|....*.
gi 334184821   780 NMDLESEKEMLKK----KVEKLEEDT 801
Cdd:pfam15921  669 LNSLSEDYEVLKRnfrnKSEEMETTT 694
 
Name Accession Description Interval E-value
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 203-801 2.27e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 2.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   203 LDSNSDVLAnvvVPLTEEYEPVNEYYPDDQTELQY-----------QQFFLHG---------KDMCKEDDVSSELEKRYK 262
Cdd:pfam15921   61 LDSPRKIIA---YPGKEHIERVLEEYSHQVKDLQRrlnesnelhekQKFYLRQsvidlqtklQEMQMERDAMADIRRRES 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   263 EAEK----RVKLLSEEMEEKKFL-SDCDFDISSLVGDIRQMEEERVGLAFEVLSLLrsqMDERASTREDIRRVKNDWDLL 337
Cdd:pfam15921  138 QSQEdlrnQLQNTVHELEAAKCLkEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL---VDFEEASGKKIYEHDSMSTMH 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   338 LKRLEKEKTELQVQLETE---LDRRSSEWTSKVESFKVEEKRLRERVreLAEHNVSLQREISTfHEKE----TERIDMIR 410
Cdd:pfam15921  215 FRSLGSAISKILRELDTEisyLKGRIFPVEDQLEALKSESQNKIELL--LQQHQDRIEQLISE-HEVEitglTEKASSAR 291

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   411 HLDETV-TELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNFEEKdmeCKELHKSVtrLLRTCKEQEKTIQgl 489
Cdd:pfam15921  292 SQANSIqSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDK---IEELEKQL--VLANSELTEARTE-- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   490 RDGFSEE--------------IKKQPSEHVDKKLQMEQL--RLVGVELS---LRKEVESMKLEAESLRRENNCLLNRVKG 550
Cdd:pfam15921  365 RDQFSQEsgnlddqlqklladLHKREKELSLEKEQNKRLwdRDTGNSITidhLRRELDDRNMEVQRLEALLKAMKSECQG 444

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   551 NGEEAdiMTTFKLDNEMKMRVCHLQDQgismLNESTQLCYKFLKIIKEKSVNSGWSEQFLIESEMRVHGIRRGTESLKRS 630
Cdd:pfam15921  445 QMERQ--MAAIQGKNESLEKVSSLTAQ----LESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAE 518

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   631 LQTVTSLLLEKSNEMASNSESSCSSAARPSSRsveKSLRAELRAETLVTSLLReklyskeQEIEQLHAEVAAGVRGNEVL 710
Cdd:pfam15921  519 ITKLRSRVDLKLQELQHLKNEGDHLRNVQTEC---EALKLQMAEKDKVIEILR-------QQIENMTQLVGQHGRTAGAM 588

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   711 QCEIQNVLDNLSLNNHQLKDLKLQMVKKDENINRME----------INLQEAAKELLTLPK-VLEEREEMWKEVKECRKR 779
Cdd:pfam15921  589 QVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEarvsdlelekVKLVNAGSERLRAVKdIKQERDQLLNEVKTSRNE 668

                          650       660
                   ....*....|....*....|....*.
gi 334184821   780 NMDLESEKEMLKK----KVEKLEEDT 801
Cdd:pfam15921  669 LNSLSEDYEVLKRnfrnKSEEMETTT 694
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 256-538 3.97e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 3.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   256 ELEKRYKEAEKRVKLLSEEMEEKKflsdcdfdisslvGDIRQMEEERVGLAFEVLSLLRSQMDERASTREDIRRVKNdWD 335
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELR-------------KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   336 LLLKRLEKEKTELQVQLETELDRRSSEWTSKVESfKVEEKRLRERVRELAEHNVSLQREISTFHEKETERIDMIRHLDET 415
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEA-EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   416 VTELSATAEEMREENLFLMQNLSKLQEsytgstdDLDYVRRNFEEKDMECKELHKSVTRLLRTCKEQEKTIQGLRDGFSE 495
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSE-------DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE 898

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 334184821   496 EIKKQpSEHVDKKLQMEQLRlvgveLSLRKEVESMKLEAESLR 538
Cdd:TIGR02168  899 LSEEL-RELESKRSELRREL-----EELREKLAQLELRLEGLE 935
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 256-805 6.11e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 6.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 256 ELEKRYKEAEKRVKLLSEEMEEKKF-LSDCDFDISSLVGDIRQMEEERVGLAFEvlslLRSQMDERASTREDIRRVKNDW 334
Cdd:COG1196  250 ELEAELEELEAELAELEAELEELRLeLEELELELEEAQAEEYELLAELARLEQD----IARLEERRRELEERLEELEEEL 325

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 335 DLLLKRLEKEKTELQvQLETELDRRSSEWTSKVESFKVEEKRLRERVRELAEHNVSLQREISTFHEKETERIDM---IRH 411
Cdd:COG1196  326 AELEEELEELEEELE-ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELaaqLEE 404

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 412 LDETVTELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNFEEKDMECKELHKSVTRLLRTCKEQEKTIQGLRD 491
Cdd:COG1196  405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 492 gfsEEIKKQPSEHVDKKLQ---------------MEQLRLVGVELSLRKEVESmKLEAESLRRENNCLLNRVKGNGEEAD 556
Cdd:COG1196  485 ---ELAEAAARLLLLLEAEadyegflegvkaallLAGLRGLAGAVAVLIGVEA-AYEAALEAALAAALQNIVVEDDEVAA 560

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 557 IMT-----------TFKLDNEMKmrvchlQDQGISMLNESTQLCYKFLKIIKEKSVNSGWSEQFLIESEMRVHGIRRGtE 625
Cdd:COG1196  561 AAIeylkaakagraTFLPLDKIR------ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL-E 633

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 626 SLKRSLQTVTSLLLEKSNEMASNSESSCSSAARPSSRSvEKSLRAELRAETLVTSLLREKLYSKEQEIEQLHAEVAAGVR 705
Cdd:COG1196  634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL-AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 706 GNEVLQCEIQnvldnlslnnhQLKDLKLQMVKKDENINRMEINLQEAAKELLTLPKVLEEREEMWKEVKECRKR------ 779
Cdd:COG1196  713 EEERLEEELE-----------EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREiealgp 781

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|
gi 334184821 780 -NM---------------------DLESEKEMLKKKVEKLEEDT--LFKE 805
Cdd:COG1196  782 vNLlaieeyeeleerydflseqreDLEEARETLEEAIEEIDRETreRFLE 831
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
249-486 8.57e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.11  E-value: 8.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 249 KEDDVSSELEkRYKEAEKRVK--------LLSEEMEEKKFLSDCDFDISSLVGDIRQMEEERVGLAFEVlSLLRSQMDER 320
Cdd:PRK02224 214 ELAELDEEIE-RYEEQREQARetrdeadeVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEV-RDLRERLEEL 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 321 ASTREDIRRVKNDWDLLLKRLEKEKTELQVQlETELDRRSSEWTSKVESFKVEEKRLRERVRELAEHNVSLQREISTfhe 400
Cdd:PRK02224 292 EEERDDLLAEAGLDDADAEAVEARREELEDR-DEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAE--- 367

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 401 keteridmirhLDETVTELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNFEEKDMECKELHKSVTRLLRTCK 480
Cdd:PRK02224 368 -----------LESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR 436


                 ....*.
gi 334184821 481 EQEKTI 486
Cdd:PRK02224 437 TARERV 442
 
Name Accession Description Interval E-value
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 203-801 2.27e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 2.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   203 LDSNSDVLAnvvVPLTEEYEPVNEYYPDDQTELQY-----------QQFFLHG---------KDMCKEDDVSSELEKRYK 262
Cdd:pfam15921   61 LDSPRKIIA---YPGKEHIERVLEEYSHQVKDLQRrlnesnelhekQKFYLRQsvidlqtklQEMQMERDAMADIRRRES 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   263 EAEK----RVKLLSEEMEEKKFL-SDCDFDISSLVGDIRQMEEERVGLAFEVLSLLrsqMDERASTREDIRRVKNDWDLL 337
Cdd:pfam15921  138 QSQEdlrnQLQNTVHELEAAKCLkEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL---VDFEEASGKKIYEHDSMSTMH 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   338 LKRLEKEKTELQVQLETE---LDRRSSEWTSKVESFKVEEKRLRERVreLAEHNVSLQREISTfHEKE----TERIDMIR 410
Cdd:pfam15921  215 FRSLGSAISKILRELDTEisyLKGRIFPVEDQLEALKSESQNKIELL--LQQHQDRIEQLISE-HEVEitglTEKASSAR 291

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   411 HLDETV-TELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNFEEKdmeCKELHKSVtrLLRTCKEQEKTIQgl 489
Cdd:pfam15921  292 SQANSIqSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDK---IEELEKQL--VLANSELTEARTE-- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   490 RDGFSEE--------------IKKQPSEHVDKKLQMEQL--RLVGVELS---LRKEVESMKLEAESLRRENNCLLNRVKG 550
Cdd:pfam15921  365 RDQFSQEsgnlddqlqklladLHKREKELSLEKEQNKRLwdRDTGNSITidhLRRELDDRNMEVQRLEALLKAMKSECQG 444

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   551 NGEEAdiMTTFKLDNEMKMRVCHLQDQgismLNESTQLCYKFLKIIKEKSVNSGWSEQFLIESEMRVHGIRRGTESLKRS 630
Cdd:pfam15921  445 QMERQ--MAAIQGKNESLEKVSSLTAQ----LESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAE 518

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   631 LQTVTSLLLEKSNEMASNSESSCSSAARPSSRsveKSLRAELRAETLVTSLLReklyskeQEIEQLHAEVAAGVRGNEVL 710
Cdd:pfam15921  519 ITKLRSRVDLKLQELQHLKNEGDHLRNVQTEC---EALKLQMAEKDKVIEILR-------QQIENMTQLVGQHGRTAGAM 588

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   711 QCEIQNVLDNLSLNNHQLKDLKLQMVKKDENINRME----------INLQEAAKELLTLPK-VLEEREEMWKEVKECRKR 779
Cdd:pfam15921  589 QVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEarvsdlelekVKLVNAGSERLRAVKdIKQERDQLLNEVKTSRNE 668

                          650       660
                   ....*....|....*....|....*.
gi 334184821   780 NMDLESEKEMLKK----KVEKLEEDT 801
Cdd:pfam15921  669 LNSLSEDYEVLKRnfrnKSEEMETTT 694
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 256-538 3.97e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 3.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   256 ELEKRYKEAEKRVKLLSEEMEEKKflsdcdfdisslvGDIRQMEEERVGLAFEVLSLLRSQMDERASTREDIRRVKNdWD 335
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELR-------------KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   336 LLLKRLEKEKTELQVQLETELDRRSSEWTSKVESfKVEEKRLRERVRELAEHNVSLQREISTFHEKETERIDMIRHLDET 415
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEA-EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   416 VTELSATAEEMREENLFLMQNLSKLQEsytgstdDLDYVRRNFEEKDMECKELHKSVTRLLRTCKEQEKTIQGLRDGFSE 495
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSE-------DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE 898

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 334184821   496 EIKKQpSEHVDKKLQMEQLRlvgveLSLRKEVESMKLEAESLR 538
Cdd:TIGR02168  899 LSEEL-RELESKRSELRREL-----EELREKLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 250-475 1.63e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 1.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   250 EDDVSSELEKRYKEAEKRVKLLSEEMEEKKFLSDCDFDISSLVGDIRQMEEE------RVGLAFEVLSLLRSQMDERAST 323
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElkalreALDELRAELTLLNEEAANLRER 825

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   324 REDIRRVKNDWDLLLKRLEKEKTELQVQLE------TELDRRSSEWTSKVESFKVEEKRLRERVRELAEHNVSLQREIst 397
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIEslaaeiEELEELIEELESELEALLNERASLEEALALLRSELEELSEEL-- 903

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 334184821   398 fHEKETERIDMIRHLDETVTELSATAEEMREENLFLMQNLSKLQESYtgsTDDLDYVRRNFEEKDMECKELHKSVTRL 475
Cdd:TIGR02168  904 -RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY---SLTLEEAEALENKIEDDEEEARRRLKRL 977
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 255-799 2.30e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 2.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   255 SELEKRYKEAEKRVKLLSEEmeekkfLSDCDFDISSLVGDIRQMEEERVGLAFEVLSLLRS---QMDERASTREDIRRVK 331
Cdd:TIGR02168  277 SELEEEIEELQKELYALANE------ISRLEQQKQILRERLANLERQLEELEAQLEELESKldeLAEELAELEEKLEELK 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   332 NDWDLLLKRLEKEKTELQV------QLETELDRRSSEW---TSKVESFKVEEKRLRERVRELAEHNVSLQREISTfHEKE 402
Cdd:TIGR02168  351 EELESLEAELEELEAELEElesrleELEEQLETLRSKVaqlELQIASLNNEIERLEARLERLEDRRERLQQEIEE-LLKK 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   403 TERIDMiRHLDETVTELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNFEEKDMECKEL------HKSVTRLL 476
Cdd:TIGR02168  430 LEEAEL-KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLerlqenLEGFSEGV 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   477 RTCKEQEKTIQGLRDGFSEEIKKQP----------SEHVDKKL---------------QMEQLRLVGVELSLRKEVESMK 531
Cdd:TIGR02168  509 KALLKNQSGLSGILGVLSELISVDEgyeaaieaalGGRLQAVVvenlnaakkaiaflkQNELGRVTFLPLDSIKGTEIQG 588

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   532 LEAESLRRENNCL--LNRVKGNGEEADIMTTFKLDNemkMRVCHLQDQGISMLNestQLCYKFLKIIKE-KSVNSGWSEQ 608
Cdd:TIGR02168  589 NDREILKNIEGFLgvAKDLVKFDPKLRKALSYLLGG---VLVVDDLDNALELAK---KLRPGYRIVTLDgDLVRPGGVIT 662

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   609 FliESEMRVHGI---RRGTESLKRSLQTVTSLLLEKSNEMASNSESSCSSAARpssrsvEKSLRAELRAETLVTSLLREK 685
Cdd:TIGR02168  663 G--GSAKTNSSIlerRREIEELEEKIEELEEKIAELEKALAELRKELEELEEE------LEQLRKELEELSRQISALRKD 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   686 LYSKEQEIEQLHAEVAAGVRGNEVLQCEIQNVLDNLSLNNHQLKDLKLQMVKKDENINRMEINLQEAAKELLTLPKVL-- 763
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELtl 814

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 334184821   764 ---------EEREEMWKEVKECRKRNMDLESEKEMLKKKVEKLEE 799
Cdd:TIGR02168  815 lneeaanlrERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 338-556 5.62e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 5.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   338 LKRLEKEKTELQVQLEtELDRRSSEWTSKVESFKVEEKRLRERVRELAEHNVSLQREISTFHEketeridMIRHLDETVT 417
Cdd:TIGR02168  241 LEELQEELKEAEEELE-ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQ-------QKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   418 ELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNFEEKDMECKELHKSVTRLLRTCKEQEKTIQGLRDGFSEei 497
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-- 390

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 334184821   498 kkqpsehvdKKLQMEQlrlvgvelsLRKEVESMKLEAESLRRENNCLLNRVKGNGEEAD 556
Cdd:TIGR02168  391 ---------LELQIAS---------LNNEIERLEARLERLEDRRERLQQEIEELLKKLE 431
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 256-805 6.11e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 6.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 256 ELEKRYKEAEKRVKLLSEEMEEKKF-LSDCDFDISSLVGDIRQMEEERVGLAFEvlslLRSQMDERASTREDIRRVKNDW 334
Cdd:COG1196  250 ELEAELEELEAELAELEAELEELRLeLEELELELEEAQAEEYELLAELARLEQD----IARLEERRRELEERLEELEEEL 325

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 335 DLLLKRLEKEKTELQvQLETELDRRSSEWTSKVESFKVEEKRLRERVRELAEHNVSLQREISTFHEKETERIDM---IRH 411
Cdd:COG1196  326 AELEEELEELEEELE-ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELaaqLEE 404

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 412 LDETVTELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNFEEKDMECKELHKSVTRLLRTCKEQEKTIQGLRD 491
Cdd:COG1196  405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 492 gfsEEIKKQPSEHVDKKLQ---------------MEQLRLVGVELSLRKEVESmKLEAESLRRENNCLLNRVKGNGEEAD 556
Cdd:COG1196  485 ---ELAEAAARLLLLLEAEadyegflegvkaallLAGLRGLAGAVAVLIGVEA-AYEAALEAALAAALQNIVVEDDEVAA 560

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 557 IMT-----------TFKLDNEMKmrvchlQDQGISMLNESTQLCYKFLKIIKEKSVNSGWSEQFLIESEMRVHGIRRGtE 625
Cdd:COG1196  561 AAIeylkaakagraTFLPLDKIR------ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL-E 633

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 626 SLKRSLQTVTSLLLEKSNEMASNSESSCSSAARPSSRSvEKSLRAELRAETLVTSLLREKLYSKEQEIEQLHAEVAAGVR 705
Cdd:COG1196  634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL-AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 706 GNEVLQCEIQnvldnlslnnhQLKDLKLQMVKKDENINRMEINLQEAAKELLTLPKVLEEREEMWKEVKECRKR------ 779
Cdd:COG1196  713 EEERLEEELE-----------EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREiealgp 781

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|
gi 334184821 780 -NM---------------------DLESEKEMLKKKVEKLEEDT--LFKE 805
Cdd:COG1196  782 vNLlaieeyeeleerydflseqreDLEEARETLEEAIEEIDRETreRFLE 831
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
249-486 8.57e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.11  E-value: 8.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 249 KEDDVSSELEkRYKEAEKRVK--------LLSEEMEEKKFLSDCDFDISSLVGDIRQMEEERVGLAFEVlSLLRSQMDER 320
Cdd:PRK02224 214 ELAELDEEIE-RYEEQREQARetrdeadeVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEV-RDLRERLEEL 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 321 ASTREDIRRVKNDWDLLLKRLEKEKTELQVQlETELDRRSSEWTSKVESFKVEEKRLRERVRELAEHNVSLQREISTfhe 400
Cdd:PRK02224 292 EEERDDLLAEAGLDDADAEAVEARREELEDR-DEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAE--- 367

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 401 keteridmirhLDETVTELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNFEEKDMECKELHKSVTRLLRTCK 480
Cdd:PRK02224 368 -----------LESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR 436


                 ....*.
gi 334184821 481 EQEKTI 486
Cdd:PRK02224 437 TARERV 442
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 251-555 1.97e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 1.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   251 DDVSSELEKRYK------EAEKRVKLLSEEMEEKkflsdcdfDISSLVGDIRQMEEERVGLAFEV--------------- 309
Cdd:TIGR02168  192 EDILNELERQLKslerqaEKAERYKELKAELREL--------ELALLVLRLEELREELEELQEELkeaeeeleeltaelq 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   310 -----LSLLRSQMDERASTREDIRRVKNDWDLLLKRLEKEKTELQVQLE------TELDRRSSEWTSKVESFKVEEKRLR 378
Cdd:TIGR02168  264 eleekLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnlerqlEELEAQLEELESKLDELAEELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   379 ERVRELAEHNVSLQREISTFHEKETERIDMIRHLDETVTELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNF 458
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   459 EE--KDMECKELHKSVTRLLRTCKEQEKTIQGLRDGfsEEIKKQPSEHVDKKLQMEQlrlvgvelSLRKEVESMKLEAES 536
Cdd:TIGR02168  424 EEllKKLEEAELKELQAELEELEEELEELQEELERL--EEALEELREELEEAEQALD--------AAERELAQLQARLDS 493

                          330
                   ....*....|....*....
gi 334184821   537 LRRenncLLNRVKGNGEEA 555
Cdd:TIGR02168  494 LER----LQENLEGFSEGV 508
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
296-428 2.90e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 2.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 296 RQMEEERVGLAFEVLSLLRSQMDERASTREDIRRVkndwDLLLKRLEKEKTELQVQLEtELDRRSSEWTSKVESFKVEEK 375
Cdd:COG2433  384 ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRL----EEQVERLEAEVEELEAELE-EKDERIERLERELSEARSEER 458

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 334184821 376 RLRERVRELaehnVSLQREISTFhEKEteridmIRHLDETVTELSATAEEMRE 428
Cdd:COG2433  459 REIRKDREI----SRLDREIERL-ERE------LEEERERIEELKRKLERLKE 500
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 249-500 3.22e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.21  E-value: 3.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   249 KEDDVSSELEKRYKEAEK--RVKLLSEEMEEKKF------LSDCDFDISSLVGDIRQMEEERVGLAFEvLSLLRSQMDER 320
Cdd:TIGR02169  192 IIDEKRQQLERLRREREKaeRYQALLKEKREYEGyellkeKEALERQKEAIERQLASLEEELEKLTEE-ISELEKRLEEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   321 ASTREDI-RRVKNDWDLLLKRLEKEKTELQVQLEtELDRRSSEWTSKVESFKVEEKRLRERVRELAEHNVSLQREISTFH 399
Cdd:TIGR02169  271 EQLLEELnKKIKDLGEEEQLRVKEKIGELEAEIA-SLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   400 EKETERIDMIRHLDETVTELSATAEEMREENLFLMQNLSKLQESYTGSTDDLDYVRRNFEEKDMECKELHKSVTRL---L 476
Cdd:TIGR02169  350 KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLnaaI 429

                          250       260
                   ....*....|....*....|....
gi 334184821   477 RTCKEQEKTIQGLRDGFSEEIKKQ 500
Cdd:TIGR02169  430 AGIEAKINELEEEKEDKALEIKKQ 453
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 255-815 3.39e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.21  E-value: 3.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   255 SELEKRYKEAEKRVKLLSEEMEE---------KKFLSDCDFDISSLVGDI----RQME--EERVGLAFEVLSLLRSQMDE 319
Cdd:TIGR02169  261 SELEKRLEEIEQLLEELNKKIKDlgeeeqlrvKEKIGELEAEIASLERSIaekeRELEdaEERLAKLEAEIDKLLAEIEE 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   320 RASTREDIRRVKNDWDLLLKRLEKEKTELQVQLEtELDRRSSEWtskVESFKVEEKRLRERVRELAEHNVSLQREISTFH 399
Cdd:TIGR02169  341 LEREIEEERKRRDKLTEEYAELKEELEDLRAELE-EVDKEFAET---RDELKDYREKLEKLKREINELKRELDRLQEELQ 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   400 EKETERIDM---IRHLDETVTELSATAEEMREENLFLMQNLSKLQEsytgstdDLDYVRRNFEEKDMECKELHKSVTRLL 476
Cdd:TIGR02169  417 RLSEELADLnaaIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAA-------DLSKYEQELYDLKEEYDRVEKELSKLQ 489

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   477 RTCKEQEKTIQGLRDgfsEEIKKQPSEHVDKKL------QMEQLRLVGVELSLRKEV------ESMKLEAESLRRENNCL 544
Cdd:TIGR02169  490 RELAEAEAQARASEE---RVRGGRAVEEVLKASiqgvhgTVAQLGSVGERYATAIEVaagnrlNNVVVEDDAVAKEAIEL 566

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   545 LNRVKGNGeeadiMTTFKLDnemKMRVCHLqDQGISMLNESTQLCYKFLKIIK--EKSVNSGWSEQFL---IESEMRVHG 619
Cdd:TIGR02169  567 LKRRKAGR-----ATFLPLN---KMRDERR-DLSILSEDGVIGFAVDLVEFDPkyEPAFKYVFGDTLVvedIEAARRLMG 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   620 IRRgteslkrsLQTVTSLLLEKSNEMASNSESSCSSAARPSSRSVE-KSLRAELRAETLVTSLLREKLYSKEQEIEQLHA 698
Cdd:TIGR02169  638 KYR--------MVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAElQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821   699 EVAAGVRGNEVLQCEIQNVLDNLSLNNHQLKDLKLQMVKKDENINRMEINLQEAAKELLTL------------------- 759
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELeedlhkleealndlearls 789

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 334184821   760 ----PKVLEEREEMWKEVKECRKRNMDLES-------EKEMLKKKVEKLEEDTLFKEGQITILKDTL 815
Cdd:TIGR02169  790 hsriPEIQAELSKLEEEVSRIEARLREIEQklnrltlEKEYLEKEIQELQEQRIDLKEQIKSIEKEI 856
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 306-539 4.05e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 40.59  E-value: 4.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 306 AFEVLSLLRSQMDErasTREDIRRVKNdwdlLLKRLekeKTELQVQL------------------ETELDRRSSEWTSKV 367
Cdd:PRK04778 196 AREILDQLEEELAA---LEQIMEEIPE----LLKEL---QTELPDQLqelkagyrelveegyhldHLDIEKEIQDLKEQI 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 368 ESFKVEEKRLRerVRELAEHNVSLQREISTFHEKETERIDMIRHLDETVTELSATAEEMREENLFLMQNLSKLQESYTGS 447
Cdd:PRK04778 266 DENLALLEELD--LDEAEEKNEEIQERIDQLYDILEREVKARKYVEKNSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLN 343

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 448 TDDLDYVrRNFEEkdmECKELHKSVTRLLRTCKEQEKTIQGLRDGFsEEIKKQPSE----HVDKKLQMEQLRLvgVELSL 523
Cdd:PRK04778 344 ESELESV-RQLEK---QLESLEKQYDEITERIAEQEIAYSELQEEL-EEILKQLEEiekeQEKLSEMLQGLRK--DELEA 416

                        250
                 ....*....|....*.
gi 334184821 524 RKEVESMKLEAESLRR 539
Cdd:PRK04778 417 REKLERYRNKLHEIKR 432
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
255-423 4.93e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 4.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 255 SELEKRYKEAEKRVKLLSEEMEEKKFLSDcdfdISSLVGDIRQMEEERVGLAfEVLSLLRSQMDERASTREDIRRvkndw 334
Cdd:COG4717   98 EELEEELEELEAELEELREELEKLEKLLQ----LLPLYQELEALEAELAELP-ERLEELEERLEELRELEEELEE----- 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 335 dlllkrLEKEKTELQVQLETELDRRSSEWTSKVESFKVEEKRLRERVRELAEHNVSLQREISTfHEKETERIDMIRHLDE 414
Cdd:COG4717  168 ------LEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEE-LEEELEQLENELEAAA 240


                 ....*....
gi 334184821 415 TVTELSATA 423
Cdd:COG4717  241 LEERLKEAR 249
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 295-540 5.52e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.31  E-value: 5.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 295 IRQMEE--ERVGLafeVLSLLRSQMD------ERAST----REDIRRVKNDWDLL-LKRLEKEKTELQVQLEtELDRRSS 361
Cdd:COG1196  181 LEATEEnlERLED---ILGELERQLEplerqaEKAERyrelKEELKELEAELLLLkLRELEAELEELEAELE-ELEAELE 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 362 EWTSKVESFKVEEKRLRERVRELAEHNVSLQREISTFHEKETERIDMIRHLDETVTELSATAEEMREENLFLMQNLSKLQ 441
Cdd:COG1196  257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 442 ESYTGSTDDLDYVRRNFEEKDMECKELHKSVTRLLRTCKEQEKTIQGLRDGFSEEIKKQpsehvdKKLQMEQLRLVGVEL 521
Cdd:COG1196  337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA------AELAAQLEELEEAEE 410

                        250
                 ....*....|....*....
gi 334184821 522 SLRKEVESMKLEAESLRRE 540
Cdd:COG1196  411 ALLERLERLEEELEELEEA 429
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
257-800 6.23e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 40.05  E-value: 6.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 257 LEKRYKEAEKRVKLLSEEMEEKKFLSDCDFDISSLvgdIRQMEEERVglafEVLSLLRSQMDERASTREDIRRVKNdwdl 336
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEEL---IKEKEKELE----EVLREINEISSELPELREELEKLEK---- 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 337 LLKRLEKEKTELqvqleTELDRRssewtskVESFKVEEKRLRERVRELAEHNVSLQREISTFHEKEtERIDMIRHLDETV 416
Cdd:PRK03918 229 EVKELEELKEEI-----EELEKE-------LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV-KELKELKEKAEEY 295

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 417 TELSATAEEMREEnlflMQNLSKLQESYTGSTDDLDYVRRNFEEKDMECKELHKSVTRLLRTCKEQE---------KTIQ 487
Cdd:PRK03918 296 IKLSEFYEEYLDE----LREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyeeaKAKK 371

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 488 GLRDGFSEEIKKQPSEHVDKKLQMEQLRLVGVELSLrKEVESMKLEAESLRRENNCLLNRVKG-------------NGEE 554
Cdd:PRK03918 372 EELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEI-SKITARIGELKKEIKELKKAIEELKKakgkcpvcgreltEEHR 450

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 555 ADIMTTFKLD-NEMKMRVCHLQDQGISMLNESTQLcYKFLKIIKEKSVNSGWSEQFL-IESEMRVHGIRRgTESLKRSLQ 632
Cdd:PRK03918 451 KELLEEYTAElKRIEKELKEIEEKERKLRKELREL-EKVLKKESELIKLKELAEQLKeLEEKLKKYNLEE-LEKKAEEYE 528

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 633 TVTSLLLEKSNEMASNSESSCSSAA-RPSSRSVEKSLR-AELRAETLVTSLLR------EKLYSKEQEIEQLHAEVAagv 704
Cdd:PRK03918 529 KLKEKLIKLKGEIKSLKKELEKLEElKKKLAELEKKLDeLEEELAELLKELEElgfesvEELEERLKELEPFYNEYL--- 605

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 705 rgnevlqcEIQNVLDNLSLNNHQLKDLKLQMVKKDENINRMEINLQEAAKELLTLPKVL--EEREEMWKEVKECRKRNMD 782
Cdd:PRK03918 606 --------ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYseEEYEELREEYLELSRELAG 677

                        570
                 ....*....|....*...
gi 334184821 783 LESEKEMLKKKVEKLEED 800
Cdd:PRK03918 678 LRAELEELEKRREEIKKT 695
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
341-484 7.31e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 39.84  E-value: 7.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334184821 341 LEKEKTELQVQLETELDRRSSEWTSKVESFKVEEKRLRERVRELAEHNVSLQREIstfHEKETEridmIRHLDETVTEL- 419
Cdd:COG2433  382 LEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEL---EEKDER----IERLERELSEAr 454

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 334184821 420 SATAEEMREENlflmqNLSKLQEsytgstdDLDYVRRNFEEKDMECKELHKSVTRLLRTCKEQEK 484
Cdd:COG2433  455 SEERREIRKDR-----EISRLDR-------EIERLERELEEERERIEELKRKLERLKELWKLEHS 507
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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