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Conserved domains on  [gi|320542261|ref|NP_001188658|]
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forked, isoform H [Drosophila melanogaster]

Protein Classification

ankyrin repeat domain-containing protein( domain architecture ID 11429852)

ankyrin repeat domain-containing protein; ANK proteins mediate specific protein-protein interactions without necessarily recognizing specific primary sequences which allows for one ankyrin repeat domain to recognize and bind to a variety of intracellular substrates and may be involved in a wide array of functions

Gene Ontology:  GO:0005515
PubMed:  17176038
SCOP:  4000366

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
393-563 6.46e-38

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 144.71  E-value: 6.46e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  393 RPNGGALALHYAAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLvLEAGGSLYVRARDGMAPIHA 472
Cdd:COG0666    83 KDDGGNTLLHAAARNGDLEIVKLLLEAGADV--NARDKDGETPLHLAAYNGNLEIVKLL-LEAGADVNAQDNDGNTPLHL 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  473 ASQMGCLDCLKWMVqDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLSL-DKYGKSPINDAAENQQVECLNVL 551
Cdd:COG0666   160 AAANGNLEIVKLLL-EAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAkDNDGKTALDLAAENGNLEIVKLL 238

                         170
                  ....*....|..
gi 320542261  552 VQHGTSVDYNGK 563
Cdd:COG0666   239 LEAGADLNAKDK 250
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
393-563 6.46e-38

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 144.71  E-value: 6.46e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  393 RPNGGALALHYAAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLvLEAGGSLYVRARDGMAPIHA 472
Cdd:COG0666    83 KDDGGNTLLHAAARNGDLEIVKLLLEAGADV--NARDKDGETPLHLAAYNGNLEIVKLL-LEAGADVNAQDNDGNTPLHL 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  473 ASQMGCLDCLKWMVqDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLSL-DKYGKSPINDAAENQQVECLNVL 551
Cdd:COG0666   160 AAANGNLEIVKLLL-EAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAkDNDGKTALDLAAENGNLEIVKLL 238

                         170
                  ....*....|..
gi 320542261  552 VQHGTSVDYNGK 563
Cdd:COG0666   239 LEAGADLNAKDK 250
Ank_2 pfam12796
Ankyrin repeats (3 copies);
470-561 3.86e-19

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 83.63  E-value: 3.86e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261   470 IHAASQMGCLDCLKWMVQdQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHgAKLSLDKYGKSPINDAAENQQVECLN 549
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLE-NGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDNGRTALHYAARSGHLEIVK 78

                           90
                   ....*....|..
gi 320542261   550 VLVQHGTSVDYN 561
Cdd:pfam12796   79 LLLEKGADINVK 90
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 490-554 2.48e-10

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 65.30  E-value: 2.48e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 320542261  490 GVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLS-LDKYGKSPINDAAENQQVECLNVLVQH 554
Cdd:PTZ00322  105 GADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTlLDKDGKTPLELAEENGFREVVQLLSRH 170
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 499-526 3.81e-05

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 42.19  E-value: 3.81e-05
                            10        20
                    ....*....|....*....|....*...
gi 320542261    499 DGATPLHFAASRGHLSVVRWLLNHGAKL 526
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLDKGADI 28
trp TIGR00870
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...
 418-558 2.37e-04

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273311 [Multi-domain]  Cd Length: 743  Bit Score: 46.23  E-value: 2.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261   418 AASVDICANTQMDNDvtPVYLAAQEGHLEVLKFLVLEAGGSLYVrardGMAPIHAAS---QMGCLDCLKWMVQDQGVDPN 494
Cdd:TIGR00870   40 PKKLNINCPDRLGRS--ALFVAAIENENLELTELLLNLSCRGAV----GDTLLHAISleyVDAVEAILLHLLAAFRKSGP 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261   495 L-----RDGD----GATPLHFAASRGHLSVVRWLLNHGAKLSLD---------------KYGKSPINDAAENQQVECLNV 550
Cdd:TIGR00870  114 LelandQYTSeftpGITALHLAAHRQNYEIVKLLLERGASVPARacgdffvksqgvdsfYHGESPLNAAACLGSPSIVAL 193


                   ....*...
gi 320542261   551 LVQHGTSV 558
Cdd:TIGR00870  194 LSEDPADI 201
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
393-563 6.46e-38

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 144.71  E-value: 6.46e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  393 RPNGGALALHYAAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLvLEAGGSLYVRARDGMAPIHA 472
Cdd:COG0666    83 KDDGGNTLLHAAARNGDLEIVKLLLEAGADV--NARDKDGETPLHLAAYNGNLEIVKLL-LEAGADVNAQDNDGNTPLHL 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  473 ASQMGCLDCLKWMVqDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLSL-DKYGKSPINDAAENQQVECLNVL 551
Cdd:COG0666   160 AAANGNLEIVKLLL-EAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAkDNDGKTALDLAAENGNLEIVKLL 238

                         170
                  ....*....|..
gi 320542261  552 VQHGTSVDYNGK 563
Cdd:COG0666   239 LEAGADLNAKDK 250
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
394-564 2.29e-30

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 122.76  E-value: 2.29e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  394 PNGGALALHYAAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLvLEAGGSLYVRARDGMAPIHAA 473
Cdd:COG0666    51 DALGALLLLAAALAGDLLVALLLLAAGADI--NAKDDGGNTLLHAAARNGDLEIVKLL-LEAGADVNARDKDGETPLHLA 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  474 SQMGCLDCLKWMVqDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKL-SLDKYGKSPINDAAENQQVECLNVLV 552
Cdd:COG0666   128 AYNGNLEIVKLLL-EAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVnARDNDGETPLHLAAENGHLEIVKLLL 206

                         170
                  ....*....|....*
gi 320542261  553 QHG---TSVDYNGKS 564
Cdd:COG0666   207 EAGadvNAKDNDGKT 221
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
395-551 1.11e-27

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 115.05  E-value: 1.11e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  395 NGGALALHYAAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLvLEAGGSLYVRARDGMAPIHAAS 474
Cdd:COG0666   118 KDGETPLHLAAYNGNLEIVKLLLEAGADV--NAQDNDGNTPLHLAAANGNLEIVKLL-LEAGADVNARDNDGETPLHLAA 194

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 320542261  475 QMGCLDCLKWMVqDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLSL-DKYGKSPINDAAENQQVECLNVL 551
Cdd:COG0666   195 ENGHLEIVKLLL-EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAkDKDGLTALLLAAAAGAALIVKLL 271
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
395-537 1.17e-19

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 91.55  E-value: 1.17e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  395 NGGALALHYAAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLvLEAGGSLYVRARDGMAPIHAAS 474
Cdd:COG0666   151 NDGNTPLHLAAANGNLEIVKLLLEAGADV--NARDNDGETPLHLAAENGHLEIVKLL-LEAGADVNAKDNDGKTALDLAA 227

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 320542261  475 QMGCLDCLKwMVQDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLSLDKYGKSPIN 537
Cdd:COG0666   228 ENGNLEIVK-LLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
Ank_2 pfam12796
Ankyrin repeats (3 copies);
470-561 3.86e-19

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 83.63  E-value: 3.86e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261   470 IHAASQMGCLDCLKWMVQdQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHgAKLSLDKYGKSPINDAAENQQVECLN 549
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLE-NGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDNGRTALHYAARSGHLEIVK 78

                           90
                   ....*....|..
gi 320542261   550 VLVQHGTSVDYN 561
Cdd:pfam12796   79 LLLEKGADINVK 90
Ank_2 pfam12796
Ankyrin repeats (3 copies);
401-497 8.01e-17

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 77.08  E-value: 8.01e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261   401 LHYAAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLVLEAGGSLYVrarDGMAPIHAASQMGCLD 480
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADA--NLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNLKD---NGRTALHYAARSGHLE 75

                           90
                   ....*....|....*..
gi 320542261   481 CLKWMVqDQGVDPNLRD 497
Cdd:pfam12796   76 IVKLLL-EKGADINVKD 91
Ank_4 pfam13637
Ankyrin repeats (many copies);
466-520 4.56e-14

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 68.07  E-value: 4.56e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 320542261   466 GMAPIHAASQMGCLDCLKWMVQdQGVDPNLRDGDGATPLHFAASRGHLSVVRWLL 520
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLE-KGADINAVDGNGETALHFAASNGNVEVLKLLL 54
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
415-559 1.20e-12

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 70.75  E-value: 1.20e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  415 LLVAASVDICANTQMDNDVTPVYLAAQEGHLEVLKFLVLEAGGSLYVRARDGMAPIHAASQMGCLDCLKWMVQDQGVDPN 494
Cdd:COG0666     2 LLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADIN 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 320542261  495 LRDGDGATPLHFAASRGHLSVVRWLLNHGAKL-SLDKYGKSPINDAAENQQVECLNVLVQHGTSVD 559
Cdd:COG0666    82 AKDDGGNTLLHAAARNGDLEIVKLLLEAGADVnARDKDGETPLHLAAYNGNLEIVKLLLEAGADVN 147
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 490-554 2.48e-10

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 65.30  E-value: 2.48e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 320542261  490 GVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLS-LDKYGKSPINDAAENQQVECLNVLVQH 554
Cdd:PTZ00322  105 GADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTlLDKDGKTPLELAEENGFREVVQLLSRH 170
Ank_4 pfam13637
Ankyrin repeats (many copies);
400-452 7.77e-10

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 56.13  E-value: 7.77e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 320542261   400 ALHYAAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLV 452
Cdd:pfam13637    4 ALHAAAASGHLELLRLLLEKGADI--NAVDGNGETALHFAASNGNVEVLKLLL 54
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 434-563 1.01e-09

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 62.70  E-value: 1.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  434 TPVYLAAQEGHLEVLKFLVLEAGGSLYVRARDGMAPIHAASQMGCLDCLKWMVQdQGVDPNLRDGDGATPLHFAASRGHL 513
Cdd:PHA02875   70 SELHDAVEEGDVKAVEELLDLGKFADDVFYKDGMTPLHLATILKKLDIMKLLIA-RGADPDIPNTDKFSPLHLAVMMGDI 148

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 320542261  514 SVVRWLLNHGAKLSL-DKYGKSPINDAAENQQVECLNVLVQHGTSVDYNGK 563
Cdd:PHA02875  149 KGIELLIDHKACLDIeDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGK 199
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 401-555 3.13e-09

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 61.16  E-value: 3.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  401 LHYAAARGCLDCVQLLVAASVDIcantqmdNDV------TPVYLAAQEGHLEVLKFLvLEAGGSLYVRARDGMAPIHAAS 474
Cdd:PHA02875   72 LHDAVEEGDVKAVEELLDLGKFA-------DDVfykdgmTPLHLATILKKLDIMKLL-IARGADPDIPNTDKFSPLHLAV 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  475 QMGCLDCLKWMVqDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAklSLDKYGKSP----INDAAENQQVECLNV 550
Cdd:PHA02875  144 MMGDIKGIELLI-DHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGA--NIDYFGKNGcvaaLCYAIENNKIDIVRL 220


                  ....*
gi 320542261  551 LVQHG 555
Cdd:PHA02875  221 FIKRG 225
Ank_5 pfam13857
Ankyrin repeats (many copies);
485-536 9.17e-09

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 53.12  E-value: 9.17e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 320542261   485 MVQDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLSL-DKYGKSPI 536
Cdd:pfam13857    1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLkDEEGLTAL 53
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 401-539 1.33e-08

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 59.21  E-value: 1.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  401 LHYAAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLVlEAGGSLYVRARDGMAPIHAASQMGCLD 480
Cdd:PHA02874  128 LHYAIKKGDLESIKMLFEYGADV--NIEDDNGCYPIHIAIKHNFFDIIKLLL-EKGAYANVKDNNGESPLHNAAEYGDYA 204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  481 CLKWMVQ---------DQGVDP---------------------NLRDGDGATPLHFAASRG-HLSVVRWLLNHGAKLSL- 528
Cdd:PHA02874  205 CIKLLIDhgnhimnkcKNGFTPlhnaiihnrsaiellinnasiNDQDIDGSTPLHHAINPPcDIDIIDILLYHKADISIk 284

                         170
                  ....*....|.
gi 320542261  529 DKYGKSPINDA 539
Cdd:PHA02874  285 DNKGENPIDTA 295
Ank_2 pfam12796
Ankyrin repeats (3 copies);
397-452 1.96e-08

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 53.20  E-value: 1.96e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 320542261   397 GALALHYAAARGCLDCVQLLVA-ASVDICantqmDNDVTPVYLAAQEGHLEVLKFLV 452
Cdd:pfam12796   30 GRTALHLAAKNGHLEIVKLLLEhADVNLK-----DNGRTALHYAARSGHLEIVKLLL 81
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 411-539 2.40e-08

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 58.44  E-value: 2.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  411 DCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLvLEAGGSLYVRARDGMAPIHAASQMGCLDCLKWMVQdQG 490
Cdd:PHA02874  105 DMIKTILDCGIDV--NIKDAELKTFLHYAIKKGDLESIKML-FEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLE-KG 180

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 320542261  491 VDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLSLD-KYGKSPINDA 539
Cdd:PHA02874  181 AYANVKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKcKNGFTPLHNA 230
Ank_4 pfam13637
Ankyrin repeats (many copies);
502-552 1.78e-07

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 49.20  E-value: 1.78e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 320542261   502 TPLHFAASRGHLSVVRWLLNHGAKLS-LDKYGKSPINDAAENQQVECLNVLV 552
Cdd:pfam13637    3 TALHAAAASGHLELLRLLLEKGADINaVDGNGETALHFAASNGNVEVLKLLL 54
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 452-558 1.60e-06

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 52.66  E-value: 1.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  452 VLEAGGSLYVRARDGMAPIHAASQMGCLDCLKwMVQDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLSL-DK 530
Cdd:PHA02874  110 ILDCGIDVNIKDAELKTFLHYAIKKGDLESIK-MLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVkDN 188

                          90       100
                  ....*....|....*....|....*...
gi 320542261  531 YGKSPINDAAENQQVECLNVLVQHGTSV 558
Cdd:PHA02874  189 NGESPLHNAAEYGDYACIKLLIDHGNHI 216
PHA03095 PHA03095
ankyrin-like protein; Provisional
 397-527 2.15e-06

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 52.33  E-value: 2.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  397 GALALHYAAARGCLDC---VQLLVAASVDIcaNTQMDNDVTPVYLAAQEGH-LEVLKFLVlEAGGSLYVRARDGMAPIHA 472
Cdd:PHA03095   47 GKTPLHLYLHYSSEKVkdiVRLLLEAGADV--NAPERCGFTPLHLYLYNATtLDVIKLLI-KAGADVNAKDKVGRTPLHV 123

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 320542261  473 asqmgCL-------DCLKWMVqDQGVDPNLRDGDGATPLH-FAASRG-HLSVVRWLLNHGAKLS 527
Cdd:PHA03095  124 -----YLsgfninpKVIRLLL-RKGADVNALDLYGMTPLAvLLKSRNaNVELLRLLIDAGADVY 181
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 324-524 3.68e-06

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 52.18  E-value: 3.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  324 LSHNTKLNNLHSNKLLHSNQSHSSSINpstrmhshqLDSYLGGVGSMMNLGGMGQVGQMYHPGSVSGSErpngGALALHY 403
Cdd:PLN03192  498 LQHHKELHDLNVGDLLGDNGGEHDDPN---------MASNLLTVASTGNAALLEELLKAKLDPDIGDSK----GRTPLHI 564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  404 AAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGHLEVLKFLVLEAGGSLYVRARDGMApihAASQMGCLDCLK 483
Cdd:PLN03192  565 AASKGYEDCVLVLLKHACNV--HIRDANGNTALWNAISAKHHKIFRILYHFASISDPHAAGDLLC---TAAKRNDLTAMK 639

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 320542261  484 WMVQdQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGA 524
Cdd:PLN03192  640 ELLK-QGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGA 679
Ank_4 pfam13637
Ankyrin repeats (many copies);
434-486 9.01e-06

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 44.57  E-value: 9.01e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 320542261   434 TPVYLAAQEGHLEVLKFLvLEAGGSLYVRARDGMAPIHAASQMGCLDCLKWMV 486
Cdd:pfam13637    3 TALHAAAASGHLELLRLL-LEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 499-526 3.17e-05

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 42.28  E-value: 3.17e-05
                           10        20
                   ....*....|....*....|....*....
gi 320542261   499 DGATPLHFAASR-GHLSVVRWLLNHGAKL 526
Cdd:pfam00023    1 DGNTPLHLAAGRrGNLEIVKLLLSKGADV 29
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 424-564 3.20e-05

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 48.42  E-value: 3.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  424 CANTQMDNDVTPVYLAAQEGHLEVLKfLVLEAGGSLYVRARDGMAPIHAASQMGCLDCLKWMVQ---------------- 487
Cdd:PHA02874   27 CINISVDETTTPLIDAIRSGDAKIVE-LFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDngvdtsilpipciekd 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  488 ------DQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKLSL-DKYGKSPINDAAENQQVECLNVLVQHGTSV-- 558
Cdd:PHA02874  106 miktilDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIeDDNGCYPIHIAIKHNFFDIIKLLLEKGAYAnv 185


                  ....*..
gi 320542261  559 -DYNGKS 564
Cdd:PHA02874  186 kDNNGES 192
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 499-526 3.81e-05

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 42.19  E-value: 3.81e-05
                            10        20
                    ....*....|....*....|....*...
gi 320542261    499 DGATPLHFAASRGHLSVVRWLLNHGAKL 526
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLDKGADI 28
Ank_3 pfam13606
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 499-527 4.00e-05

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.


Pssm-ID: 463933 [Multi-domain]  Cd Length: 30  Bit Score: 42.24  E-value: 4.00e-05
                           10        20
                   ....*....|....*....|....*....
gi 320542261   499 DGATPLHFAASRGHLSVVRWLLNHGAKLS 527
Cdd:pfam13606    1 DGNTPLHLAARNGRLEIVKLLLENGADIN 29
PHA03095 PHA03095
ankyrin-like protein; Provisional
 400-521 4.48e-05

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 48.10  E-value: 4.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  400 ALHYAA--ARGCLDCVQLLVAASVDICANTQMDNdvTPVYLAAQEG---HLEVLKFLvlEAGGSLYVRARDGMAPIHAAS 474
Cdd:PHA03095  190 LLHHHLqsFKPRARIVRELIRAGCDPAATDMLGN--TPLHSMATGSsckRSLVLPLL--IAGISINARNRYGQTPLHYAA 265

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 320542261  475 ----QMGCLDCLKwmvqdQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLN 521
Cdd:PHA03095  266 vfnnPRACRRLIA-----LGADINAVSSDGNTPLSLMVRNNNGRAVRAALA 311
PHA02946 PHA02946
ankyin-like protein; Provisional
 489-559 8.26e-05

ankyin-like protein; Provisional


Pssm-ID: 165256 [Multi-domain]  Cd Length: 446  Bit Score: 47.36  E-value: 8.26e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 320542261  489 QGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKL-SLDKYGKSPIN--DAAENQQVECLNVLVQHGTSVD 559
Cdd:PHA02946   61 RGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPnACDKQHKTPLYylSGTDDEVIERINLLVQYGAKIN 134
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 426-559 1.50e-04

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 46.78  E-value: 1.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  426 NTQMDNDVTPVYLAAQEGHLEVLkflvLEAGGSLYVRARDGMAPIHAASQMGCLDCLKWMVQdQGVDPNLRDGDGATPLH 505
Cdd:PLN03192  522 DPNMASNLLTVASTGNAALLEEL----LKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLK-HACNVHIRDANGNTALW 596

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 320542261  506 FAASRGHLSVVrWLLNHGAKLSLDKYGKSPINDAAENQQVECLNVLVQHGTSVD 559
Cdd:PLN03192  597 NAISAKHHKIF-RILYHFASISDPHAAGDLLCTAAKRNDLTAMKELLKQGLNVD 649
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 413-559 1.52e-04

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 46.41  E-value: 1.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  413 VQLLVAASVDICANTQmDNDVTPVYLAAQEGHLEVLKFLVLEaGGSLYVRARDGMAPIHAASQMGCLDCLKWMVQDqGVD 492
Cdd:PHA02878  150 TKLLLSYGADINMKDR-HKGNTALHYATENKDQRLTELLLSY-GANVNIPDKTNNSPLHHAVKHYNKPIVHILLEN-GAS 226

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  493 PNLRDGDGATPLHFAASR-GHLSVVRWLLNHGAKLSLDKY--GKSPINDAAENQQVecLNVLVQHGTSVD 559
Cdd:PHA02878  227 TDARDKCGNTPLHISVGYcKDYDILKLLLEHGVDVNAKSYilGLTALHSSIKSERK--LKLLLEYGADIN 294
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 399-564 2.26e-04

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 45.81  E-value: 2.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  399 LALHYAAARGCLDCVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGH-----LEVLKFLvLEAGGSLYVRARDGMAPIHAA 473
Cdd:PHA03100   37 LPLYLAKEARNIDVVKILLDNGADI--NSSTKNNSTPLHYLSNIKYnltdvKEIVKLL-LEYGANVNAPDNNGITPLLYA 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  474 SQ--MGCLDCLKWMVqDQGVDPNLRDGDGATPLHFAASRGH--LSVVRWLLNHGAK----------LSL-------DKYG 532
Cdd:PHA03100  114 ISkkSNSYSIVEYLL-DNGANVNIKNSDGENLLHLYLESNKidLKILKLLIDKGVDinaknrvnylLSYgvpinikDVYG 192

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 320542261  533 KSPINDAAENQQVECLNVLVQHGTS---VDYNGKS 564
Cdd:PHA03100  193 FTPLHYAVYNNNPEFVKYLLDLGANpnlVNKYGDT 227
trp TIGR00870
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...
 418-558 2.37e-04

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273311 [Multi-domain]  Cd Length: 743  Bit Score: 46.23  E-value: 2.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261   418 AASVDICANTQMDNDvtPVYLAAQEGHLEVLKFLVLEAGGSLYVrardGMAPIHAAS---QMGCLDCLKWMVQDQGVDPN 494
Cdd:TIGR00870   40 PKKLNINCPDRLGRS--ALFVAAIENENLELTELLLNLSCRGAV----GDTLLHAISleyVDAVEAILLHLLAAFRKSGP 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261   495 L-----RDGD----GATPLHFAASRGHLSVVRWLLNHGAKLSLD---------------KYGKSPINDAAENQQVECLNV 550
Cdd:TIGR00870  114 LelandQYTSeftpGITALHLAAHRQNYEIVKLLLERGASVPARacgdffvksqgvdsfYHGESPLNAAACLGSPSIVAL 193


                   ....*...
gi 320542261   551 LVQHGTSV 558
Cdd:TIGR00870  194 LSEDPADI 201
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 401-526 4.28e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 45.05  E-value: 4.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  401 LHYAAARGCLD-CVQLLVAASVDIcaNTQMDNDVTPVYLAAQEGH-LEVLKFLVLEAGGslyVRARDGM--APIHAASQM 476
Cdd:PHA02876  277 LHHASQAPSLSrLVPKLLERGADV--NAKNIKGETPLYLMAKNGYdTENIRTLIMLGAD---VNAADRLyiTPLHQASTL 351

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 320542261  477 GCLDCLKWMVQDQGVDPNLRDGDGATPLHFAASRGHLSVVRWLLNHGAKL 526
Cdd:PHA02876  352 DRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADI 401
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 420-559 1.47e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 43.51  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542261  420 SVDICANTqmdndvtPVYLAAQEGHLEVLKFLVLEAGGSLYVRARDGMAPIHAASQMGC-LDCLKWMVQdQGVDPNLRDG 498
Cdd:PHA02876  268 SIDDCKNT-------PLHHASQAPSLSRLVPKLLERGADVNAKNIKGETPLYLMAKNGYdTENIRTLIM-LGADVNAADR 339

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 320542261  499 DGATPLHFAASRG-HLSVVRWLLNHGAKLSL-DKYGKSPINDAAENQQVECLNVLVQHGTSVD 559
Cdd:PHA02876  340 LYITPLHQASTLDrNKDIVITLLELGANVNArDYCDKTPIHYAAVRNNVVIINTLLDYGADIE 402
Ank_5 pfam13857
Ankyrin repeats (many copies);
458-507 2.45e-03

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 37.71  E-value: 2.45e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 320542261   458 SLYVRARDGMAPIHAASQMGCLDCLKWMVqDQGVDPNLRDGDGATPLHFA 507
Cdd:pfam13857    8 DLNRLDGEGYTPLHVAAKYGALEIVRVLL-AYGVDLNLKDEEGLTALDLA 56
Ank_2 pfam12796
Ankyrin repeats (3 copies);
395-426 6.84e-03

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 37.40  E-value: 6.84e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 320542261   395 NGGALALHYAAARGCLDCVQLLVAASVDICAN 426
Cdd:pfam12796   59 DNGRTALHYAARSGHLEIVKLLLEKGADINVK 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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