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Conserved domains on  [gi|334183669|ref|NP_001185326|]
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Translation initiation factor eIF3 subunit [Arabidopsis thaliana]

Protein Classification

eukaryotic translation initiation factor 3 subunit J( domain architecture ID 10554295)

eukaryotic translation initiation factor 3 (eIF3) subunit J is a component of the eIF3 complex that is required for several steps in the initiation of protein synthesis

CATH:  1.10.246.60
Gene Ontology:  GO:0003743|GO:0005852|GO:0006413|GO:0001732|GO:0042802

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
eIF3_subunit pfam08597
Translation initiation factor eIF3 subunit; This is a family of proteins which are subunits of ...
 1-185 1.82e-38

Translation initiation factor eIF3 subunit; This is a family of proteins which are subunits of the eukaryotic translation initiation factor 3 (eIF3). In yeast it is called Hcr1. The Saccharomyces cerevisiae protein Swiss:Q05775 has been shown to be required for processing of 20S pre-rRNA and binds to 18S rRNA and eIF3 subunits Rpg1p and Prt1p.


:

Pssm-ID: 462530  Cd Length: 239  Bit Score: 133.19  E-value: 1.82e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334183669    1 MDDWEDEKIAP--LPAKVELKSNWDDEDvDENEIKDSWEDDDDEPAQPPVINPAPEKAPKKA----APKTVEKKG--KAV 72
Cdd:pfam08597   1 MSDWDDEDFEPssPAPPPARRDKWDDED-EDEDVKDSWDAEEEEEEEKEKAAKAAAAKAKKKkkskKQKIAEKEAerKAE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334183669   73 EVPKEAPKEKPLDPIAEKLRQQRLVEEADYRATAELFG------VKDDDKNLDMFIPKSESDFLEYAEMISHRIKPYEKS 146
Cdd:pfam08597  80 EEAEEEEELTPEDEAARKLRLRKAEEESDLENAADLFGgagdptKDTDLSSLDLFNPKTKEDFEELRKALAPKLTKYEKK 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 334183669  147 Y-HYIALLKTIMRLSLTNMKAADVKDVASSITTIANEKLK 185
Cdd:pfam08597 160 SpHYSAFLEELIRDLAKPLSSEDIKKIASSLTVLANEKQK 199
 
Name Accession Description Interval E-value
eIF3_subunit pfam08597
Translation initiation factor eIF3 subunit; This is a family of proteins which are subunits of ...
 1-185 1.82e-38

Translation initiation factor eIF3 subunit; This is a family of proteins which are subunits of the eukaryotic translation initiation factor 3 (eIF3). In yeast it is called Hcr1. The Saccharomyces cerevisiae protein Swiss:Q05775 has been shown to be required for processing of 20S pre-rRNA and binds to 18S rRNA and eIF3 subunits Rpg1p and Prt1p.


Pssm-ID: 462530  Cd Length: 239  Bit Score: 133.19  E-value: 1.82e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334183669    1 MDDWEDEKIAP--LPAKVELKSNWDDEDvDENEIKDSWEDDDDEPAQPPVINPAPEKAPKKA----APKTVEKKG--KAV 72
Cdd:pfam08597   1 MSDWDDEDFEPssPAPPPARRDKWDDED-EDEDVKDSWDAEEEEEEEKEKAAKAAAAKAKKKkkskKQKIAEKEAerKAE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334183669   73 EVPKEAPKEKPLDPIAEKLRQQRLVEEADYRATAELFG------VKDDDKNLDMFIPKSESDFLEYAEMISHRIKPYEKS 146
Cdd:pfam08597  80 EEAEEEEELTPEDEAARKLRLRKAEEESDLENAADLFGgagdptKDTDLSSLDLFNPKTKEDFEELRKALAPKLTKYEKK 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 334183669  147 Y-HYIALLKTIMRLSLTNMKAADVKDVASSITTIANEKLK 185
Cdd:pfam08597 160 SpHYSAFLEELIRDLAKPLSSEDIKKIASSLTVLANEKQK 199
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 6-99 2.59e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 38.46  E-value: 2.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334183669   6 DEKIAPLPAKVE--------LKSNWDDEDVDENEIKDSWEDDDD---EPAQPPviNPAPEKAPKKAAPKTvekkgkavEV 74
Cdd:NF033838 368 EEKIKQAKAKVEskkaeatrLEKIKTDRKKAEEEAKRKAAEEDKvkeKPAEQP--QPAPAPQPEKPAPKP--------EK 437

                         90       100
                 ....*....|....*....|....*.
gi 334183669  75 PKEAPK-EKPLDPIAEKLRQQRLVEE 99
Cdd:NF033838 438 PAEQPKaEKPADQQAEEDYARRSEEE 463
 
Name Accession Description Interval E-value
eIF3_subunit pfam08597
Translation initiation factor eIF3 subunit; This is a family of proteins which are subunits of ...
 1-185 1.82e-38

Translation initiation factor eIF3 subunit; This is a family of proteins which are subunits of the eukaryotic translation initiation factor 3 (eIF3). In yeast it is called Hcr1. The Saccharomyces cerevisiae protein Swiss:Q05775 has been shown to be required for processing of 20S pre-rRNA and binds to 18S rRNA and eIF3 subunits Rpg1p and Prt1p.


Pssm-ID: 462530  Cd Length: 239  Bit Score: 133.19  E-value: 1.82e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334183669    1 MDDWEDEKIAP--LPAKVELKSNWDDEDvDENEIKDSWEDDDDEPAQPPVINPAPEKAPKKA----APKTVEKKG--KAV 72
Cdd:pfam08597   1 MSDWDDEDFEPssPAPPPARRDKWDDED-EDEDVKDSWDAEEEEEEEKEKAAKAAAAKAKKKkkskKQKIAEKEAerKAE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334183669   73 EVPKEAPKEKPLDPIAEKLRQQRLVEEADYRATAELFG------VKDDDKNLDMFIPKSESDFLEYAEMISHRIKPYEKS 146
Cdd:pfam08597  80 EEAEEEEELTPEDEAARKLRLRKAEEESDLENAADLFGgagdptKDTDLSSLDLFNPKTKEDFEELRKALAPKLTKYEKK 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 334183669  147 Y-HYIALLKTIMRLSLTNMKAADVKDVASSITTIANEKLK 185
Cdd:pfam08597 160 SpHYSAFLEELIRDLAKPLSSEDIKKIASSLTVLANEKQK 199
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 6-99 2.59e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 38.46  E-value: 2.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334183669   6 DEKIAPLPAKVE--------LKSNWDDEDVDENEIKDSWEDDDD---EPAQPPviNPAPEKAPKKAAPKTvekkgkavEV 74
Cdd:NF033838 368 EEKIKQAKAKVEskkaeatrLEKIKTDRKKAEEEAKRKAAEEDKvkeKPAEQP--QPAPAPQPEKPAPKP--------EK 437

                         90       100
                 ....*....|....*....|....*.
gi 334183669  75 PKEAPK-EKPLDPIAEKLRQQRLVEE 99
Cdd:NF033838 438 PAEQPKaEKPADQQAEEDYARRSEEE 463
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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