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Conserved domains on  [gi|334182701|ref|NP_001185041|]
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Mannose-binding lectin superfamily protein [Arabidopsis thaliana]

Protein Classification

jacalin family lectin( domain architecture ID 10176320)

jacalin family lectin is a sugar-binding protein containing a jacalin domain

Gene Ontology:  GO:0030246
PubMed:  15329359|28737678
SCOP:  4002758

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 24-152 1.76e-38

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


:

Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 138.08  E-value: 1.76e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  24 GHAWDDGMYTT-VKQIIIAHG-SGIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVkFDYPHEYLISVNGTYGSFdvWGTI 101
Cdd:cd09612    1 GSAWDDGVFPDgLRKITVRSGeNGIDSIKFEYDKDGQHVVGPWHGGGGGTPEEIV-LDYPDEYITSVSGTYGPV--SGSN 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 334182701 102 CVRSLTFESNRRKYGPFGVDSGTFFALPKSGSKIIGFHGKAGWYLDAIGVH 152
Cdd:cd09612   78 VITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVY 128
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 254-380 1.28e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


:

Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 133.08  E-value: 1.28e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 254 FDDGIY-TGIRQINLSRNV-GIVSMKVCYDFRGQAVWGSKHGGVGGFKhDKIVFDYPSEVLTHVTGTYGPlmYMGPNVIK 331
Cdd:cd09612    4 WDDGVFpDGLRKITVRSGEnGIDSIKFEYDKDGQHVVGPWHGGGGGTP-EEIVLDYPDEYITSVSGTYGP--VSGSNVIT 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 334182701 332 SLTFRTNRGKHGPYGEEQGPSFTHQMDEGKVVGFLGREGLFLDSIGVHV 380
Cdd:cd09612   81 SLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYV 129
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 450-582 2.43e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


:

Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 132.30  E-value: 2.43e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 450 QAWDDGVF-SGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHGGdsNGVATHRIKFEYPDESITCISGYYGPLNnsdRY 528
Cdd:cd09612    2 SAWDDGVFpDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGG--GGGTPEEIVLDYPDEYITSVSGTYGPVS---GS 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 334182701 529 NVVKSLSFYTSRGRYGPYGEETGTFFTSTTTQGKVLGFHGRSSFHLDAIGVHMQ 582
Cdd:cd09612   77 NVITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
 
Name Accession Description Interval E-value
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 24-152 1.76e-38

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 138.08  E-value: 1.76e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  24 GHAWDDGMYTT-VKQIIIAHG-SGIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVkFDYPHEYLISVNGTYGSFdvWGTI 101
Cdd:cd09612    1 GSAWDDGVFPDgLRKITVRSGeNGIDSIKFEYDKDGQHVVGPWHGGGGGTPEEIV-LDYPDEYITSVSGTYGPV--SGSN 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 334182701 102 CVRSLTFESNRRKYGPFGVDSGTFFALPKSGSKIIGFHGKAGWYLDAIGVH 152
Cdd:cd09612   78 VITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVY 128
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 254-380 1.28e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 133.08  E-value: 1.28e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 254 FDDGIY-TGIRQINLSRNV-GIVSMKVCYDFRGQAVWGSKHGGVGGFKhDKIVFDYPSEVLTHVTGTYGPlmYMGPNVIK 331
Cdd:cd09612    4 WDDGVFpDGLRKITVRSGEnGIDSIKFEYDKDGQHVVGPWHGGGGGTP-EEIVLDYPDEYITSVSGTYGP--VSGSNVIT 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 334182701 332 SLTFRTNRGKHGPYGEEQGPSFTHQMDEGKVVGFLGREGLFLDSIGVHV 380
Cdd:cd09612   81 SLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYV 129
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 450-582 2.43e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 132.30  E-value: 2.43e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 450 QAWDDGVF-SGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHGGdsNGVATHRIKFEYPDESITCISGYYGPLNnsdRY 528
Cdd:cd09612    2 SAWDDGVFpDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGG--GGGTPEEIVLDYPDEYITSVSGTYGPVS---GS 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 334182701 529 NVVKSLSFYTSRGRYGPYGEETGTFFTSTTTQGKVLGFHGRSSFHLDAIGVHMQ 582
Cdd:cd09612   77 NVITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 24-155 1.80e-32

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 121.61  E-value: 1.80e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701   24 GHAWDDGMYTTVKQI-IIAHGSGIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVKFDYPHEYLISVNGTYGSFDVWGTIC 102
Cdd:pfam01419   1 GASWDDGVYDGVRKVyVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 334182701  103 VRSLTFESNRRKYGP-FGVDSGTFFALPKSGSKIIGFHGKAGWYLDAIGVHTQP 155
Cdd:pfam01419  81 ITSLTFKTNKGRTSPfFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 251-380 4.78e-31

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 117.33  E-value: 4.78e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701   251 GIMFDDGIYTGIRQINLSRN-VGIVSMKVCYDFrGQAVWGSKHGGVGGfkHDKIVFDYPSEVLTHVTGTYGPLmymgpNV 329
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGgEGIKSIQFDYDK-GGKVWGDEHGGKGG--TGEEILLYPGEYITSVEGTYDKS-----GV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 334182701   330 IKSLTFRTNRGKHGP-YGEEQGPSFTHQMDEG-KVVGFLGRE-GLFLDSIGVHV 380
Cdd:smart00915  73 ITSLTFKTNKGRTSPfGGYEGGTKFVLESKEGkKIVGFHGRSsGDGLDSLGAYF 126
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 24-155 2.07e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 115.40  E-value: 2.07e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701    24 GHAWDDGMYTTVKQIIIAHG-SGIDSIQIEYDKNGsSVWSEkrGGKGGKKFDKVKFDYPHEYLISVNGTYGSfdvwgTIC 102
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGgEGIKSIQFDYDKGG-KVWGD--EHGGKGGTGEEILLYPGEYITSVEGTYDK-----SGV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 334182701   103 VRSLTFESNRRKYGP-FGVDSGTFFALP-KSGSKIIGFHG-KAGWYLDAIGVHTQP 155
Cdd:smart00915  73 ITSLTFKTNKGRTSPfGGYEGGTKFVLEsKEGKKIVGFHGrSSGDGLDSLGAYFSP 128
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 452-580 6.13e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 114.25  E-value: 6.13e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701   452 WDDGVFSGIKQIFVTRGNDAITSIQIEYDrNGQSVWSIKHGGDSNgvaTHRIKFEYPDESITCISGYYGPlnnsdrYNVV 531
Cdd:smart00915   4 WDDGAFDGVRKIYVGQGGEGIKSIQFDYD-KGGKVWGDEHGGKGG---TGEEILLYPGEYITSVEGTYDK------SGVI 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 334182701   532 KSLSFYTSRGRYGP-YGEETGTFFTSTTTQGKVL-GFHGRSS-FHLDAIGVH 580
Cdd:smart00915  74 TSLTFKTNKGRTSPfGGYEGGTKFVLESKEGKKIvGFHGRSSgDGLDSLGAY 125
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 451-580 3.11e-28

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 109.67  E-value: 3.11e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  451 AWDDGVFSGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHgGDSNGVATHRIKFEYPDESITCISGYYGPLNNSDrYNV 530
Cdd:pfam01419   3 SWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEH-GKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSD-SEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 334182701  531 VKSLSFYTSRGRYGPYGEETGTFFTSTTTQG-KVLGFHGRSSFHLDAIGVH 580
Cdd:pfam01419  81 ITSLTFKTNKGRTSPFFGTPSGTKFSLEVKGkKIVGFHGRAGNALNALGAY 131
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 254-380 4.80e-27

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 106.21  E-value: 4.80e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  254 FDDGIYTGIRQINLSR-NVGIVSMKVCYDFRGQAVWGSKHGGVGGFKHDKIVFDYPSEVLTHVTGTYGPLMYMGPNVIKS 332
Cdd:pfam01419   4 WDDGVYDGVRKVYVGQgGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEVITS 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 334182701  333 LTFRTNRGKHGP-YGEEQGPSFTHQMDEGKVVGFLGREGLFLDSIGVHV 380
Cdd:pfam01419  84 LTFKTNKGRTSPfFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYF 132
PLN02193 PLN02193
nitrile-specifier protein
 451-581 9.00e-10

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 61.12  E-value: 9.00e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 451 AWDDGVFSGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHGGDSN-GVATHRIKfeyPDESITCISGYYGPLNNSDRyN 529
Cdd:PLN02193  15 VWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTElGVEEFEID---ADDYIVYVEGYREKVNDMTS-E 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 334182701 530 VVKSLSFYTSRGRYGPYGEETGTFFTSTTTqGKVLGFHGRSSFHLDAIGVHM 581
Cdd:PLN02193  91 MITFLSFKTYKGKTSHPIEKRPGVKFVLQG-GKIVGFHGRSTDVLHSLGAYI 141
PLN02193 PLN02193
nitrile-specifier protein
 247-380 3.71e-09

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 59.20  E-value: 3.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 247 GGTGGIMFDDGIYTGIRQINLSR-NVGIVSMKVCYDFRGQAVWGSKHG-----GVGGFKHDkivfdyPSEVLTHVTGTYG 320
Cdd:PLN02193   9 GGETGDVWDDGVYDNVRKVYVGQgQYGIAFVKFEYVNGSQVVVGDEHGkktelGVEEFEID------ADDYIVYVEGYRE 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334182701 321 PLMYMGPNVIKSLTFRTNRGKHG-PYGEEQGPSFTHQmdEGKVVGFLGREGLFLDSIGVHV 380
Cdd:PLN02193  83 KVNDMTSEMITFLSFKTYKGKTShPIEKRPGVKFVLQ--GGKIVGFHGRSTDVLHSLGAYI 141
PLN02193 PLN02193
nitrile-specifier protein
 20-166 4.15e-08

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 56.12  E-value: 4.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  20 GGQSGHAWDDGMYTTVKQIIIAHGS-GIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVKFDyPHEYLISVNGTYGSFDVW 98
Cdd:PLN02193   9 GGETGDVWDDGVYDNVRKVYVGQGQyGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEID-ADDYIVYVEGYREKVNDM 87

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334182701  99 GTICVRSLTFESNRRKYG-PFGVDSGTFFALpkSGSKIIGFHGKAGWYLDAIG--VHTQPIPKENNPSSKI 166
Cdd:PLN02193  88 TSEMITFLSFKTYKGKTShPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGayISLPSTPKLLGKWIKV 156
 
Name Accession Description Interval E-value
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 24-152 1.76e-38

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 138.08  E-value: 1.76e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  24 GHAWDDGMYTT-VKQIIIAHG-SGIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVkFDYPHEYLISVNGTYGSFdvWGTI 101
Cdd:cd09612    1 GSAWDDGVFPDgLRKITVRSGeNGIDSIKFEYDKDGQHVVGPWHGGGGGTPEEIV-LDYPDEYITSVSGTYGPV--SGSN 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 334182701 102 CVRSLTFESNRRKYGPFGVDSGTFFALPKSGSKIIGFHGKAGWYLDAIGVH 152
Cdd:cd09612   78 VITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVY 128
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 254-380 1.28e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 133.08  E-value: 1.28e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 254 FDDGIY-TGIRQINLSRNV-GIVSMKVCYDFRGQAVWGSKHGGVGGFKhDKIVFDYPSEVLTHVTGTYGPlmYMGPNVIK 331
Cdd:cd09612    4 WDDGVFpDGLRKITVRSGEnGIDSIKFEYDKDGQHVVGPWHGGGGGTP-EEIVLDYPDEYITSVSGTYGP--VSGSNVIT 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 334182701 332 SLTFRTNRGKHGPYGEEQGPSFTHQMDEGKVVGFLGREGLFLDSIGVHV 380
Cdd:cd09612   81 SLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYV 129
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 450-582 2.43e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 132.30  E-value: 2.43e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 450 QAWDDGVF-SGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHGGdsNGVATHRIKFEYPDESITCISGYYGPLNnsdRY 528
Cdd:cd09612    2 SAWDDGVFpDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGG--GGGTPEEIVLDYPDEYITSVSGTYGPVS---GS 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 334182701 529 NVVKSLSFYTSRGRYGPYGEETGTFFTSTTTQGKVLGFHGRSSFHLDAIGVHMQ 582
Cdd:cd09612   77 NVITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 24-155 1.80e-32

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 121.61  E-value: 1.80e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701   24 GHAWDDGMYTTVKQI-IIAHGSGIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVKFDYPHEYLISVNGTYGSFDVWGTIC 102
Cdd:pfam01419   1 GASWDDGVYDGVRKVyVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 334182701  103 VRSLTFESNRRKYGP-FGVDSGTFFALPKSGSKIIGFHGKAGWYLDAIGVHTQP 155
Cdd:pfam01419  81 ITSLTFKTNKGRTSPfFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 251-380 4.78e-31

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 117.33  E-value: 4.78e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701   251 GIMFDDGIYTGIRQINLSRN-VGIVSMKVCYDFrGQAVWGSKHGGVGGfkHDKIVFDYPSEVLTHVTGTYGPLmymgpNV 329
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGgEGIKSIQFDYDK-GGKVWGDEHGGKGG--TGEEILLYPGEYITSVEGTYDKS-----GV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 334182701   330 IKSLTFRTNRGKHGP-YGEEQGPSFTHQMDEG-KVVGFLGRE-GLFLDSIGVHV 380
Cdd:smart00915  73 ITSLTFKTNKGRTSPfGGYEGGTKFVLESKEGkKIVGFHGRSsGDGLDSLGAYF 126
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 24-155 2.07e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 115.40  E-value: 2.07e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701    24 GHAWDDGMYTTVKQIIIAHG-SGIDSIQIEYDKNGsSVWSEkrGGKGGKKFDKVKFDYPHEYLISVNGTYGSfdvwgTIC 102
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGgEGIKSIQFDYDKGG-KVWGD--EHGGKGGTGEEILLYPGEYITSVEGTYDK-----SGV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 334182701   103 VRSLTFESNRRKYGP-FGVDSGTFFALP-KSGSKIIGFHG-KAGWYLDAIGVHTQP 155
Cdd:smart00915  73 ITSLTFKTNKGRTSPfGGYEGGTKFVLEsKEGKKIVGFHGrSSGDGLDSLGAYFSP 128
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 452-580 6.13e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 114.25  E-value: 6.13e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701   452 WDDGVFSGIKQIFVTRGNDAITSIQIEYDrNGQSVWSIKHGGDSNgvaTHRIKFEYPDESITCISGYYGPlnnsdrYNVV 531
Cdd:smart00915   4 WDDGAFDGVRKIYVGQGGEGIKSIQFDYD-KGGKVWGDEHGGKGG---TGEEILLYPGEYITSVEGTYDK------SGVI 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 334182701   532 KSLSFYTSRGRYGP-YGEETGTFFTSTTTQGKVL-GFHGRSS-FHLDAIGVH 580
Cdd:smart00915  74 TSLTFKTNKGRTSPfGGYEGGTKFVLESKEGKKIvGFHGRSSgDGLDSLGAY 125
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 451-580 3.11e-28

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 109.67  E-value: 3.11e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  451 AWDDGVFSGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHgGDSNGVATHRIKFEYPDESITCISGYYGPLNNSDrYNV 530
Cdd:pfam01419   3 SWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEH-GKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSD-SEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 334182701  531 VKSLSFYTSRGRYGPYGEETGTFFTSTTTQG-KVLGFHGRSSFHLDAIGVH 580
Cdd:pfam01419  81 ITSLTFKTNKGRTSPFFGTPSGTKFSLEVKGkKIVGFHGRAGNALNALGAY 131
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 254-380 4.80e-27

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 106.21  E-value: 4.80e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  254 FDDGIYTGIRQINLSR-NVGIVSMKVCYDFRGQAVWGSKHGGVGGFKHDKIVFDYPSEVLTHVTGTYGPLMYMGPNVIKS 332
Cdd:pfam01419   4 WDDGVYDGVRKVYVGQgGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEVITS 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 334182701  333 LTFRTNRGKHGP-YGEEQGPSFTHQMDEGKVVGFLGREGLFLDSIGVHV 380
Cdd:pfam01419  84 LTFKTNKGRTSPfFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYF 132
PLN02193 PLN02193
nitrile-specifier protein
 451-581 9.00e-10

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 61.12  E-value: 9.00e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 451 AWDDGVFSGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHGGDSN-GVATHRIKfeyPDESITCISGYYGPLNNSDRyN 529
Cdd:PLN02193  15 VWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTElGVEEFEID---ADDYIVYVEGYREKVNDMTS-E 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 334182701 530 VVKSLSFYTSRGRYGPYGEETGTFFTSTTTqGKVLGFHGRSSFHLDAIGVHM 581
Cdd:PLN02193  91 MITFLSFKTYKGKTSHPIEKRPGVKFVLQG-GKIVGFHGRSTDVLHSLGAYI 141
PLN02193 PLN02193
nitrile-specifier protein
 247-380 3.71e-09

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 59.20  E-value: 3.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 247 GGTGGIMFDDGIYTGIRQINLSR-NVGIVSMKVCYDFRGQAVWGSKHG-----GVGGFKHDkivfdyPSEVLTHVTGTYG 320
Cdd:PLN02193   9 GGETGDVWDDGVYDNVRKVYVGQgQYGIAFVKFEYVNGSQVVVGDEHGkktelGVEEFEID------ADDYIVYVEGYRE 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334182701 321 PLMYMGPNVIKSLTFRTNRGKHG-PYGEEQGPSFTHQmdEGKVVGFLGREGLFLDSIGVHV 380
Cdd:PLN02193  83 KVNDMTSEMITFLSFKTYKGKTShPIEKRPGVKFVLQ--GGKIVGFHGRSTDVLHSLGAYI 141
PLN02193 PLN02193
nitrile-specifier protein
 20-166 4.15e-08

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 56.12  E-value: 4.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  20 GGQSGHAWDDGMYTTVKQIIIAHGS-GIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVKFDyPHEYLISVNGTYGSFDVW 98
Cdd:PLN02193   9 GGETGDVWDDGVYDNVRKVYVGQGQyGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEID-ADDYIVYVEGYREKVNDM 87

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334182701  99 GTICVRSLTFESNRRKYG-PFGVDSGTFFALpkSGSKIIGFHGKAGWYLDAIG--VHTQPIPKENNPSSKI 166
Cdd:PLN02193  88 TSEMITFLSFKTYKGKTShPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGayISLPSTPKLLGKWIKV 156
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 454-579 9.61e-08

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 50.86  E-value: 9.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 454 DGVFSGIKQIFVtRGNDAITSIQIEYDrngqSVWSIKHGGdsNGVATHRIKFEYPDESITCISGYYGplnNSDRYNVVKS 533
Cdd:cd09302    8 GGDGARLTEIRV-RSGGAVDAIRVVLR----DYTDGRHGG--NGGPNTSSVFLDPGEYITITSVSSG---DNGGGTRIDA 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 334182701 534 LSFYTSRGRYGPYGEETGTFFTSTTTQ--GKVLGFHGRSSFHLDAIGV 579
Cdd:cd09302   78 IQFTTNKGRSGTYGTTSGALGTEFTVPvgGEIVGIYGRAGDDVDAFGF 125
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 33-151 2.50e-07

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 49.71  E-value: 2.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  33 TTVKQIIIAHGSGIDSIQIEYDkngsSVWSEKRGGKGGKKFDKVKFDyPHEYLISVNGTYGsfDVWGTICVRSLTFESNR 112
Cdd:cd09302   12 ARLTEIRVRSGGAVDAIRVVLR----DYTDGRHGGNGGPNTSSVFLD-PGEYITITSVSSG--DNGGGTRIDAIQFTTNK 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 334182701 113 RKYGPFGVDS---GTFFALPkSGSKIIGFHGKAGWYLDAIGV 151
Cdd:cd09302   85 GRSGTYGTTSgalGTEFTVP-VGGEIVGIYGRAGDDVDAFGF 125
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 251-378 2.03e-06

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 47.40  E-value: 2.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 251 GIMFDD--GIYTGIRQINLSRNVGIVSMKVCYDfrgqAVWGSKHGGVGGFKHDKIVFDyPSEVLTHVTGTYGplMYMGPN 328
Cdd:cd09302    1 GKPFSDtgGDGARLTEIRVRSGGAVDAIRVVLR----DYTDGRHGGNGGPNTSSVFLD-PGEYITITSVSSG--DNGGGT 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 334182701 329 VIKSLTFRTNRGKHGPYGEEQGPS-FTHQMDEG-KVVGFLGREGLFLDSIGV 378
Cdd:cd09302   74 RIDAIQFTTNKGRSGTYGTTSGALgTEFTVPVGgEIVGIYGRAGDDVDAFGF 125
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 21-152 6.69e-06

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 45.85  E-value: 6.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  21 GQSGHAWDDGMYTTVKQIIIAHGSGIDSIQIEY-DKNGSSVWSEKRGGKGGKKFDKVkfdYPHEYLISVNGTYGSFdvwg 99
Cdd:cd09614    1 GFGGSPGSDFDILTVSAIQLRSGSYVDQIITDYqDLNGTQNFHHGGGGGNLSPTLNF---SSGEYITEVTGRSGDR---- 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 334182701 100 ticVRSLTFESNR-RKYGPFGVDSGTFFAL-PKSGSKIIGFHGKAGWYLDAIGVH 152
Cdd:cd09614   74 ---VDQVQFTTNYgGRTLPGGGGGGSAFTWtVPDNQKVIGFAGRSGSYLDQLQVY 125
Jacalin_ZG16_like cd09611
Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a ...
 460-543 1.27e-05

Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a conserved secreted vertebrate protein with tissue-specific expression profiles, which might play a role in glycoprotein secretion, perhaps as a linker protein that participates in the formation and/or transport of the zymogen granule. Its paralog ZG16b (PAUF) has been associated with roles in gene regulation and cancer. This domain family also contains mammalian proteins labelled as prostatic spermine-binding protein (SBP) and salivary-gland specific secreted proteins.


Pssm-ID: 187707 [Multi-domain]  Cd Length: 128  Bit Score: 45.01  E-value: 1.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 460 IKQIFVTRGNDAITSIQIEYDrngqSVWSIKHGGDSnGVATHRikFEYPDESITCISGYYgplnnsdrYNVVKSLSFYTS 539
Cdd:cd09611   18 ITGIRVSVGNNYIKGIQVRYG----SNWSDVYGGRG-GNEQEI--VLEPGESITKVSGSY--------KIYLHGLVFTTN 82


                 ....
gi 334182701 540 RGRY 543
Cdd:cd09611   83 KGRY 86
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 248-380 1.30e-05

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 45.08  E-value: 1.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 248 GTGGIMFDDGIYTGIRQINLSRNVGIVSMKVCYDFRGQAVWGsKHGGVGGFKHDKIVFdYPSEVLTHVTGTYGplmymgp 327
Cdd:cd09614    1 GFGGSPGSDFDILTVSAIQLRSGSYVDQIITDYQDLNGTQNF-HHGGGGGNLSPTLNF-SSGEYITEVTGRSG------- 71

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 334182701 328 NVIKSLTFRTNRG-KHGPYGEEQGPSFTHQMDEG-KVVGFLGREGLFLDSIGVHV 380
Cdd:cd09614   72 DRVDQVQFTTNYGgRTLPGGGGGGSAFTWTVPDNqKVIGFAGRSGSYLDQLQVYY 126
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 452-580 2.93e-03

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 38.15  E-value: 2.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701 452 WDDgvFSGIKQIFVT-RGNDAITSIQIEY-DRNGQSvwSIKHGGdsNGVATHRIKFEYPDESITCISGYYGplnnsdryN 529
Cdd:cd09614    7 GSD--FDILTVSAIQlRSGSYVDQIITDYqDLNGTQ--NFHHGG--GGGNLSPTLNFSSGEYITEVTGRSG--------D 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 334182701 530 VVKSLSFYTSRG-RYGPYGEETGTFFTSTTTQG-KVLGFHGRSSFHLDAIGVH 580
Cdd:cd09614   73 RVDQVQFTTNYGgRTLPGGGGGGSAFTWTVPDNqKVIGFAGRSGSYLDQLQVY 125
Jacalin_ZG16_like cd09611
Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a ...
 46-152 9.13e-03

Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a conserved secreted vertebrate protein with tissue-specific expression profiles, which might play a role in glycoprotein secretion, perhaps as a linker protein that participates in the formation and/or transport of the zymogen granule. Its paralog ZG16b (PAUF) has been associated with roles in gene regulation and cancer. This domain family also contains mammalian proteins labelled as prostatic spermine-binding protein (SBP) and salivary-gland specific secreted proteins.


Pssm-ID: 187707 [Multi-domain]  Cd Length: 128  Bit Score: 36.53  E-value: 9.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182701  46 IDSIQIEYDKNGSSVWSekrggkGGKKFDKVKFDYPHEYLISVNGTYGsfdvwgtICVRSLTFESNRRKYGPFGVDSGTF 125
Cdd:cd09611   30 IKGIQVRYGSNWSDVYG------GRGGNEQEIVLEPGESITKVSGSYK-------IYLHGLVFTTNKGRYLSFGKLRGRS 96

                         90       100       110
                 ....*....|....*....|....*....|
gi 334182701 126 F--ALPKSGSKIIGFHGKAGW-YLDAIGVH 152
Cdd:cd09611   97 FnaTPPPSNYVLRGISGRYGGlGIKSIGFH 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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